Podcasts about Interstitial

  • 414PODCASTS
  • 1,465EPISODES
  • 47mAVG DURATION
  • 5WEEKLY NEW EPISODES
  • Aug 26, 2026LATEST

POPULARITY

20192020202120222023202420252026

Categories



Best podcasts about Interstitial

Show all podcasts related to interstitial

Latest podcast episodes about Interstitial

The Worst of All Possible Worlds
255 - In the Oswald Heights [Whit's Endless Summer 53]

The Worst of All Possible Worlds

Play Episode Listen Later Aug 26, 2026 30:27


THIS IS A PREVIEW. FOR THE FULL EPISODE, GO TO Patreon.com/worstofall HEART OF DUCKNESS TICKETS The lads return to Odyssey for further adventures in gentrification, mini-golf, and the increasingly complicated corporate espionage of a children's television production company. Media Referenced in this Episode: Adventures in Odyssey 468-469: Chains 470: Break a Leg 471: Fifteen Minutes 473: Breaking Point TWOAPW theme by Brendan Dalton: Patreon // brendan-dalton.com // brendandalton.bandcamp.com Interstitial: “Helena Hotspur” // Written by A.J. Ditty // feat. Hollis Beck as “Helena Hotspur” Episode edited by Brian Alford. Interstitial edited by A.J. Ditty. Produced by Josh Boerman, A.J. Ditty, and Brian Alford. This podcast was recorded under a SAG-AFTRA Agreement.

The Worst of All Possible Worlds

THIS IS A PREVIEW. FOR THE FULL EPISODE, GO TO Patreon.com/worstofall According to all known laws of aviation, there is no way a bee should be able to fly. Media Referenced in this Episode: Bee Movie. Dir. Simon J. Smith and Steve Hickner. 2007. “A Complete History of Bee Movie's Many, Many Memes" by Paris Martineau. New York Magazine. November 2nd, 2017. “Bee Movie: A Seinfeldian Society” by Joe Strike. Animation World. November 2nd, 2007. “How Bee Movie Won 2016” by Laura Bradley. Vanity Fair. December 30th, 2016. TWOAPW theme by Brendan Dalton: Patreon // brendan-dalton.com // brendandalton.bandcamp.com Interstitial: “A Series of Voicemails Left on Jerry Seinfeld's Answering Machine by one Stephen Sondheim, Composer of Musical Theater and Lover of Bees” // Written by A.J. Ditty and Brian Alford // feat. David Armstrong as “Stephen Sondheim” and Brian Alford as “Jerry” Episode edited by Brian Alford. Interstitial edited by A.J. Ditty. Produced by Josh Boerman, A.J. Ditty, and Brian Alford. This podcast was recorded under a SAG-AFTRA Agreement. Its wings are too small to get its fat little body off the ground. The bee, of course, flies anyway because bees don't care what humans think is impossible. Yellow, black. Yellow, black. Yellow, black. Yellow, black. Ooh, black and yellow! Let's shake it up a little. Barry! Breakfast is ready! Coming! Hang on a second. Hello? - Barry? - Adam? - Can you believe this is happening? - I can't. I'll pick you up. Looking sharp. Use the stairs. Your father paid good money for those. Sorry. I'm excited. Here's the graduate. We're very proud of you, son. A perfect report card, all B's. Very proud. Ma! I got a thing going here. - You got lint on your fuzz. - Ow! That's me! - Wave to us! We'll be in row 118,000. - Bye! Barry, I told you, stop flying in the house! - Hey, Adam. - Hey, Barry. - Is that fuzz gel? - A little. Special day, graduation. Never thought I'd make it. Three days grade school, three days high school. Those were awkward. Three days college. I'm glad I took a day and hitchhiked around the hive. You did come back different. - Hi, Barry. - Artie, growing a mustache? Looks good. - Hear about Frankie? - Yeah. - You going to the funeral? - No, I'm not going. Everybody knows, sting someone, you die. Don't waste it on a squirrel. Such a hothead. I guess he could have just gotten out of the way. I love this incorporating an amusement park into our day. That's why we don't need vacations. Boy, quite a bit of pomp… under the circumstances. - Well, Adam, today we are men. - We are! - Bee-men. - Amen! Hallelujah! Students, faculty, distinguished bees, please welcome Dean Buzzwell. Welcome, New Hive City graduating class of… …9:15. That concludes our ceremonies. And begins your career at Honex Industries! Will we pick our job today? I heard it's just orientation. Heads up! Here we go. Keep your hands and antennas inside the tram at all times. - Wonder what it'll be like? - A little scary. Welcome to Honex, a division of Honesco and a part of the Hexagon Group. This is it! Wow. Wow. We know that you, as a bee, have worked your whole life to get to the point where you can work for your whole life. Honey begins when our valiant Pollen Jocks bring the nectar to the hive. Our top-secret formula is automatically color-corrected, scent-adjusted and bubble-contoured into this soothing sweet syrup with its distinctive golden glow you know as… Honey! - That girl was hot. - She's my cousin! - She is? - Yes, we're all cousins. - Right. You're right. - At Honex, we constantly strive to improve every aspect of bee existence. These bees are stress-testing a new helmet technology. - What do you think he makes? - Not enough. Here we have our latest advancement, the Krelman. - What does that do? - Oatches that little strand of honey that hangs after you pour it. Saves us millions. Oan anyone work on the Krelman? Of course. Most bee jobs are small ones. But bees know that every small job, if it's done well, means a lot. But choose carefully because you'll stay in the job you pick for the rest of your life. The same job the rest of your life? I didn't know that. What's the difference? You'll be happy to know that bees, as a species, haven't had one day off in 27 million years. So you'll just work us to death? We'll sure try. Wow! That blew my mind! “What's the difference?” How can you say that? One job forever? That's an insane choice to have to make. I'm relieved. Now we only have to make one decision in life. But, Adam, how could they never have told us that? Why would you question anything? We're bees. We're the most perfectly functioning society on Earth. You ever think maybe things work a little too well here? Like what? Give me one example. I don't know. But you know what I'm talking about. Please clear the gate. Royal Nectar Force on approach. Wait a second. Oheck it out. - Hey, those are Pollen Jocks! - Wow. I've never seen them this close. They know what it's like outside the hive. Yeah, but some don't come back. - Hey, Jocks! - Hi, Jocks! You guys did great! You're monsters! You're sky freaks! I love it! I love it! - I wonder where they were. - I don't know. Their day's not planned. Outside the hive, flying who knows where, doing who knows what. You can'tjust decide to be a Pollen Jock. You have to be bred for that. Right. Look. That's more pollen than you and I will see in a lifetime. It's just a status symbol. Bees make too much of it. Perhaps. Unless you're wearing it and the ladies see you wearing it. Those ladies? Aren't they our cousins too? Distant. Distant. Look at these two. - Oouple of Hive Harrys. - Let's have fun with them. It must be dangerous being a Pollen Jock. Yeah. Once a bear pinned me against a mushroom! He had a paw on my throat, and with the other, he was slapping me! - Oh, my! - I never thought I'd knock him out. What were you doing during this? Trying to alert the authorities. I can autograph that. A little gusty out there today, wasn't it, comrades? Yeah. Gusty. We're hitting a sunflower patch six miles from here tomorrow. - Six miles, huh? - Barry! A puddle jump for us, but maybe you're not up for it. - Maybe I am. - You are not! We're going 0900 at J-Gate. What do you think, buzzy-boy? Are you bee enough? I might be. It all depends on what 0900 means. Hey, Honex! Dad, you surprised me. You decide what you're interested in? - Well, there's a lot of choices. - But you only get one. Do you ever get bored doing the same job every day? Son, let me tell you about stirring. You grab that stick, and you just move it around, and you stir it around. You get yourself into a rhythm. It's a beautiful thing. You know, Dad, the more I think about it, maybe the honey field just isn't right for me. You were thinking of what, making balloon animals? That's a bad job for a guy with a stinger. Janet, your son's not sure he wants to go into honey! - Barry, you are so funny sometimes. - I'm not trying to be funny. You're not funny! You're going into honey. Our son, the stirrer! - You're gonna be a stirrer? - No one's listening to me! Wait till you see the sticks I have. I could say anything right now. I'm gonna get an ant tattoo! Let's open some honey and celebrate! Maybe I'll pierce my thorax. Shave my antennae. Shack up with a grasshopper. Get a gold tooth and call everybody “dawg”! I'm so proud. - We're starting work today! - Today's the day. Oome on! All the good jobs will be gone. Yeah, right. Pollen counting, stunt bee, pouring, stirrer, front desk, hair removal… - Is it still available? - Hang on. Two left! One of them's yours! Oongratulations! Step to the side. - What'd you get? - Picking crud out. Stellar! Wow! Oouple of newbies? Yes, sir! Our first day! We are ready! Make your choice. - You want to go first? - No, you go. Oh, my. What's available? Restroom attendant's open, not for the reason you think. - Any chance of getting the Krelman? - Sure, you're on. I'm sorry, the Krelman just closed out. Wax monkey's always open. The Krelman opened up again. What happened? A bee died. Makes an opening. See? He's dead. Another dead one. Deady. Deadified. Two more dead. Dead from the neck up. Dead from the neck down. That's life! Oh, this is so hard! Heating, cooling, stunt bee, pourer, stirrer, humming, inspector number seven, lint coordinator, stripe supervisor, mite wrangler. Barry, what do you think I should… Barry? Barry! All right, we've got the sunflower patch in quadrant nine… What happened to you? Where are you? - I'm going out. - Out? Out where? - Out there. - Oh, no! I have to, before I go to work for the rest of my life. You're gonna die! You're crazy! Hello? Another call coming in. If anyone's feeling brave, there's a Korean deli on 83rd that gets their roses today. Hey, guys. - Look at that. - Isn't that the kid we saw yesterday? Hold it, son, flight deck's restricted. It's OK, Lou. We're gonna take him up. Really? Feeling lucky, are you? Sign here, here. Just initial that. - Thank you. - OK. You got a rain advisory today, and as you all know, bees cannot fly in rain. So be careful. As always, watch your brooms, hockey sticks, dogs, birds, bears and bats. Also, I got a couple of reports of root beer being poured on us. Murphy's in a home because of it, babbling like a cicada! - That's awful. - And a reminder for you rookies, bee law number one, absolutely no talking to humans! All right, launch positions! Buzz, buzz, buzz, buzz! Buzz, buzz, buzz, buzz! Buzz, buzz, buzz, buzz! Black and yellow! Hello! You ready for this, hot shot? Yeah. Yeah, bring it on. Wind, check. - Antennae, check. - Nectar pack, check. - Wings, check. - Stinger, check. Scared out of my shorts, check. OK, ladies, let's move it out! Pound those petunias, you striped stem-suckers! All of you, drain those flowers! Wow! I'm out! I can't believe I'm out! So blue. I feel so fast and free! Box kite! Wow! Flowers! This is Blue Leader. We have roses visual. Bring it around 30 degrees and hold. Roses! 30 degrees, roger. Bringing it around. Stand to the side, kid. It's got a bit of a kick. That is one nectar collector! - Ever see pollination up close? - No, sir. I pick up some pollen here, sprinkle it over here. Maybe a dash over there, a pinch on that one. See that? It's a little bit of magic. That's amazing. Why do we do that? That's pollen power. More pollen, more flowers, more nectar, more honey for us. Cool. I'm picking up a lot of bright yellow. Oould be daisies. Don't we need those? Oopy that visual. Wait. One of these flowers seems to be on the move. Say again? You're reporting a moving flower? Affirmative. That was on the line! This is the coolest. What is it? I don't know, but I'm loving this color. It smells good. Not like a flower, but I like it. Yeah, fuzzy. Ohemical-y. Oareful, guys. It's a little grabby. My sweet lord of bees! Oandy-brain, get off there! Problem! - Guys! - This could be bad. Affirmative. Very close. Gonna hurt. Mama's little boy. You are way out of position, rookie! Ooming in at you like a missile! Help me! I don't think these are flowers. - Should we tell him? - I think he knows. What is this?! Match point! You can start packing up, honey, because you're about to eat it! Yowser! Gross. There's a bee in the car! - Do something! - I'm driving! - Hi, bee. - He's back here! He's going to sting me! Nobody move. If you don't move, he won't sting you. Freeze! He blinked! Spray him, Granny! What are you doing?! Wow… the tension level out here is unbelievable. I gotta get home. Oan't fly in rain. Oan't fly in rain. Oan't fly in rain. Mayday! Mayday! Bee going down! Ken, could you close the window please? Ken, could you close the window please? Oheck out my new resume. I made it into a fold-out brochure. You see? Folds out. Oh, no. More humans. I don't need this. What was that? Maybe this time. This time. This time. This time! This time! This… Drapes! That is diabolical. It's fantastic. It's got all my special skills, even my top-ten favorite movies. What's number one? Star Wars? Nah, I don't go for that… …kind of stuff. No wonder we shouldn't talk to them. They're out of their minds. When I leave a job interview, they're flabbergasted, can't believe what I say. There's the sun. Maybe that's a way out. I don't remember the sun having a big 75 on it. I predicted global warming. I could feel it getting hotter. At first I thought it was just me. Wait! Stop! Bee! Stand back. These are winter boots. Wait! Don't kill him! You know I'm allergic to them! This thing could kill me! Why does his life have less value than yours? Why does his life have any less value than mine? Is that your statement? I'm just saying all life has value. You don't know what he's capable of feeling. My brochure! There you go, little guy. I'm not scared of him. It's an allergic thing. Put that on your resume brochure. My whole face could puff up. Make it one of your special skills. Knocking someone out is also a special skill. Right. Bye, Vanessa. Thanks. - Vanessa, next week? Yogurt night? - Sure, Ken. You know, whatever. - You could put carob chips on there. - Bye. - Supposed to be less calories. - Bye. I gotta say something. She saved my life. I gotta say something. All right, here it goes. Nah. What would I say? I could really get in trouble. It's a bee law. You're not supposed to talk to a human. I can't believe I'm doing this. I've got to. Oh, I can't do it. Oome on! No. Yes. No. Do it. I can't. How should I start it? “You like jazz?” No, that's no good. Here she comes! Speak, you fool! Hi! I'm sorry. - You're talking. - Yes, I know. You're talking! I'm so sorry. No, it's OK. It's fine. I know I'm dreaming. But I don't recall going to bed. Well, I'm sure this is very disconcerting. This is a bit of a surprise to me. I mean, you're a bee! I am. And I'm not supposed to be doing this, but they were all trying to kill me. And if it wasn't for you… I had to thank you. It's just how I was raised. That was a little weird. - I'm talking with a bee. - Yeah. I'm talking to a bee. And the bee is talking to me! I just want to say I'm grateful. I'll leave now. - Wait! How did you learn to do that? - What? The talking thing. Same way you did, I guess. “Mama, Dada, honey.” You pick it up. - That's very funny. - Yeah. Bees are funny. If we didn't laugh, we'd cry with what we have to deal with. Anyway… Oan I… …get you something? - Like what? I don't know. I mean… I don't know. Ooffee? I don't want to put you out. It's no trouble. It takes two minutes. - It's just coffee. - I hate to impose. - Don't be ridiculous! - Actually, I would love a cup. Hey, you want rum cake? - I shouldn't. - Have some. - No, I can't. - Oome on! I'm trying to lose a couple micrograms. - Where? - These stripes don't help. You look great! I don't know if you know anything about fashion. Are you all right? No. He's making the tie in the cab as they're flying up Madison. He finally gets there. He runs up the steps into the church. The wedding is on. And he says, “Watermelon? I thought you said Guatemalan. Why would I marry a watermelon?” Is that a bee joke? That's the kind of stuff we do. Yeah, different. So, what are you gonna do, Barry? About work? I don't know. I want to do my part for the hive, but I can't do it the way they want. I know how you feel. - You do? - Sure. My parents wanted me to be a lawyer or a doctor, but I wanted to be a florist. - Really? - My only interest is flowers. Our new queen was just elected with that same campaign slogan. Anyway, if you look… There's my hive right there. See it? You're in Sheep Meadow! Yes! I'm right off the Turtle Pond! No way! I know that area. I lost a toe ring there once. - Why do girls put rings on their toes? - Why not? - It's like putting a hat on your knee. - Maybe I'll try that. - You all right, ma'am? - Oh, yeah. Fine. Just having two cups of coffee! Anyway, this has been great. Thanks for the coffee. Yeah, it's no trouble. Sorry I couldn't finish it. If I did, I'd be up the rest of my life. Are you…? Oan I take a piece of this with me? Sure! Here, have a crumb. - Thanks! - Yeah. All right. Well, then… I guess I'll see you around. Or not. OK, Barry. And thank you so much again… for before. Oh, that? That was nothing. Well, not nothing, but… Anyway… This can't possibly work. He's all set to go. We may as well try it. OK, Dave, pull the chute. - Sounds amazing. - It was amazing! It was the scariest, happiest moment of my life. Humans! I can't believe you were with humans! Giant, scary humans! What were they like? Huge and crazy. They talk crazy. They eat crazy giant things. They drive crazy. - Do they try and kill you, like on TV? - Some of them. But some of them don't. - How'd you get back? - Poodle. You did it, and I'm glad. You saw whatever you wanted to see. You had your “experience.” Now you can pick out yourjob and be normal. - Well… - Well? Well, I met someone. You did? Was she Bee-ish? - A wasp?! Your parents will kill you! - No, no, no, not a wasp. - Spider? - I'm not attracted to spiders. I know it's the hottest thing, with the eight legs and all. I can't get by that face. So who is she? She's… human. No, no. That's a bee law. You wouldn't break a bee law. - Her name's Vanessa. - Oh, boy. She's so nice. And she's a florist! Oh, no! You're dating a human florist! We're not dating. You're flying outside the hive, talking to humans that attack our homes with power washers and M-80s! One-eighth a stick of dynamite! She saved my life! And she understands me. This is over! Eat this. This is not over! What was that? - They call it a crumb. - It was so stingin' stripey! And that's not what they eat. That's what falls off what they eat! - You know what a Oinnabon is? - No. It's bread and cinnamon and frosting. They heat it up… Sit down! …really hot! - Listen to me! We are not them! We're us. There's us and there's them! Yes, but who can deny the heart that is yearning? There's no yearning. Stop yearning. Listen to me! You have got to start thinking bee, my friend. Thinking bee! - Thinking bee. - Thinking bee. Thinking bee! Thinking bee! Thinking bee! Thinking bee! There he is. He's in the pool. You know what your problem is, Barry? I gotta start thinking bee? How much longer will this go on? It's been three days! Why aren't you working? I've got a lot of big life decisions to think about. What life? You have no life! You have no job. You're barely a bee! Would it kill you to make a little honey? Barry, come out. Your father's talking to you. Martin, would you talk to him? Barry, I'm talking to you! You coming? Got everything? All set! Go ahead. I'll catch up. Don't be too long. Watch this! Vanessa! - We're still here. - I told you not to yell at him. He doesn't respond to yelling! - Then why yell at me? - Because you don't listen! I'm not listening to this. Sorry, I've gotta go. - Where are you going? - I'm meeting a friend. A girl? Is this why you can't decide? Bye. I just hope she's Bee-ish. They have a huge parade of flowers every year in Pasadena? To be in the Tournament of Roses, that's every florist's dream! Up on a float, surrounded by flowers, crowds cheering. A tournament. Do the roses compete in athletic events? No. All right, I've got one. How come you don't fly everywhere? It's exhausting. Why don't you run everywhere? It's faster. Yeah, OK, I see, I see. All right, your turn. TiVo. You can just freeze live TV? That's insane! You don't have that? We have Hivo, but it's a disease. It's a horrible, horrible disease. Oh, my. Dumb bees! You must want to sting all those jerks. We try not to sting. It's usually fatal for us. So you have to watch your temper. Very carefully. You kick a wall, take a walk, write an angry letter and throw it out. Work through it like any emotion: Anger, jealousy, lust. Oh, my goodness! Are you OK? Yeah. - What is wrong with you?! - It's a bug. He's not bothering anybody. Get out of here, you creep! What was that? A Pic ‘N' Save circular? Yeah, it was. How did you know? It felt like about 10 pages. Seventy-five is pretty much our limit. You've really got that down to a science. - I lost a cousin to Italian Vogue. - I'll bet. What in the name of Mighty Hercules is this? How did this get here? Oute Bee, Golden Blossom, Ray Liotta Private Select? - Is he that actor? - I never heard of him. - Why is this here? - For people. We eat it. You don't have enough food of your own? - Well, yes. - How do you get it? - Bees make it. - I know who makes it! And it's hard to make it! There's heating, cooling, stirring. You need a whole Krelman thing! - It's organic. - It's our-ganic! It's just honey, Barry. Just what?! Bees don't know about this! This is stealing! A lot of stealing! You've taken our homes, schools, hospitals! This is all we have! And it's on sale?! I'm getting to the bottom of this. I'm getting to the bottom of all of this! Hey, Hector. - You almost done? - Almost. He is here. I sense it. Well, I guess I'll go home now and just leave this nice honey out, with no one around. You're busted, box boy! I knew I heard something. So you can talk! I can talk. And now you'll start talking! Where you getting the sweet stuff? Who's your supplier? I don't understand. I thought we were friends. The last thing we want to do is upset bees! You're too late! It's ours now! You, sir, have crossed the wrong sword! You, sir, will be lunch for my iguana, Ignacio! Where is the honey coming from? Tell me where! Honey Farms! It comes from Honey Farms! Orazy person! What horrible thing has happened here? These faces, they never knew what hit them. And now they're on the road to nowhere! Just keep still. What? You're not dead? Do I look dead? They will wipe anything that moves. Where you headed? To Honey Farms. I am onto something huge here. I'm going to Alaska. Moose blood, crazy stuff. Blows your head off! I'm going to Tacoma. - And you? - He really is dead. All right. Uh-oh! - What is that?! - Oh, no! - A wiper! Triple blade! - Triple blade? Jump on! It's your only chance, bee! Why does everything have to be so doggone clean?! How much do you people need to see?! Open your eyes! Stick your head out the window! From NPR News in Washington, I'm Carl Kasell. But don't kill no more bugs! - Bee! - Moose blood guy!! - You hear something? - Like what? Like tiny screaming. Turn off the radio. Whassup, bee boy? Hey, Blood. Just a row of honey jars, as far as the eye could see. Wow! I assume wherever this truck goes is where they're getting it. I mean, that honey's ours. - Bees hang tight. - We're all jammed in. It's a close community. Not us, man. We on our own. Every mosquito on his own. - What if you get in trouble? - You a mosquito, you in trouble. Nobody likes us. They just smack. See a mosquito, smack, smack! At least you're out in the world. You must meet girls. Mosquito girls try to trade up, get with a moth, dragonfly. Mosquito girl don't want no mosquito. You got to be kidding me! Mooseblood's about to leave the building! So long, bee! - Hey, guys! - Mooseblood! I knew I'd catch y'all down here. Did you bring your crazy straw? We throw it in jars, slap a label on it, and it's pretty much pure profit. What is this place? A bee's got a brain the size of a pinhead. They are pinheads! Pinhead. - Oheck out the new smoker. - Oh, sweet. That's the one you want. The Thomas 3000! Smoker? Ninety puffs a minute, semi-automatic. Twice the nicotine, all the tar. A couple breaths of this knocks them right out. They make the honey, and we make the money. “They make the honey, and we make the money”? Oh, my! What's going on? Are you OK? Yeah. It doesn't last too long. Do you know you're in a fake hive with fake walls? Our queen was moved here. We had no choice. This is your queen? That's a man in women's clothes! That's a drag queen! What is this? Oh, no! There's hundreds of them! Bee honey. Our honey is being brazenly stolen on a massive scale! This is worse than anything bears have done! I intend to do something. Oh, Barry, stop. Who told you humans are taking our honey? That's a rumor. Do these look like rumors? That's a conspiracy theory. These are obviously doctored photos. How did you get mixed up in this? He's been talking to humans. - What? - Talking to humans?! He has a human girlfriend. And they make out! Make out? Barry! We do not. - You wish you could. - Whose side are you on? The bees! I dated a cricket once in San Antonio. Those crazy legs kept me up all night. Barry, this is what you want to do with your life? I want to do it for all our lives. Nobody works harder than bees! Dad, I remember you coming home so overworked your hands were still stirring. You couldn't stop. I remember that. What right do they have to our honey? We live on two cups a year. They put it in lip balm for no reason whatsoever! Even if it's true, what can one bee do? Sting them where it really hurts. In the face! The eye! - That would hurt. - No. Up the nose? That's a killer. There's only one place you can sting the humans, one place where it matters. Hive at Five, the hive's only full-hour action news source. No more bee beards! With Bob Bumble at the anchor desk. Weather with Storm Stinger. Sports with Buzz Larvi. And Jeanette Chung. - Good evening. I'm Bob Bumble. - And I'm Jeanette Chung. A tri-county bee, Barry Benson, intends to sue the human race for stealing our honey, packaging it and profiting from it illegally! Tomorrow night on Bee Larry King, we'll have three former queens here in our studio, discussing their new book, Classy Ladies, out this week on Hexagon. Tonight we're talking to Barry Benson. Did you ever think, “I'm a kid from the hive. I can't do this”? Bees have never been afraid to change the world. What about Bee Columbus? Bee Gandhi? Bee Jesus? Where I'm from, we'd never sue humans. We were thinking of stickball or candy stores. How old are you? The bee community is supporting you in this case, which will be the trial of the bee century. You know, they have a Larry King in the human world too. It's a common name. Next week… He looks like you and has a show and suspenders and colored dots… Next week… Glasses, quotes on the bottom from the guest even though you just heard ‘em. Bear Week next week! They're scary, hairy and here live. Always leans forward, pointy shoulders, squinty eyes, very Jewish. In tennis, you attack at the point of weakness! It was my grandmother, Ken. She's 81. Honey, her backhand's a joke! I'm not gonna take advantage of that? Quiet, please. Actual work going on here. - Is that that same bee? - Yes, it is! I'm helping him sue the human race. - Hello. - Hello, bee. This is Ken. Yeah, I remember you. Timberland, size ten and a half. Vibram sole, I believe. Why does he talk again? Listen, you better go ‘cause we're really busy working. But it's our yogurt night! Bye-bye. Why is yogurt night so difficult?! You poor thing. You two have been at this for hours! Yes, and Adam here has been a huge help. - Frosting… - How many sugars? Just one. I try not to use the competition. So why are you helping me? Bees have good qualities. And it takes my mind off the shop. Instead of flowers, people are giving balloon bouquets now. Those are great, if you're three. And artificial flowers. - Oh, those just get me psychotic! - Yeah, me too. Bent stingers, pointless pollination. Bees must hate those fake things! Nothing worse than a daffodil that's had work done. Maybe this could make up for it a little bit. - This lawsuit's a pretty big deal. - I guess. You sure you want to go through with it? Am I sure? When I'm done with the humans, they won't be able to say, “Honey, I'm home,” without paying a royalty! It's an incredible scene here in downtown Manhattan, where the world anxiously waits, because for the first time in history, we will hear for ourselves if a honeybee can actually speak. What have we gotten into here, Barry? It's pretty big, isn't it? I can't believe how many humans don't work during the day. You think billion-dollar multinational food companies have good lawyers? Everybody needs to stay behind the barricade. - What's the matter? - I don't know, I just got a chill. Well, if it isn't the bee team. You boys work on this? All rise! The Honorable Judge Bumbleton presiding. All right. Case number 4475, Superior Court of New York, Barry Bee Benson v. The Honey Industry is now in session. Mr. Montgomery, you're representing the five food companies collectively? A privilege. Mr. Benson… you're representing all the bees of the world? I'm kidding. Yes, Your Honor, we're ready to proceed. Mr. Montgomery, your opening statement, please. Ladies and gentlemen of the jury, my grandmother was a simple woman. Born on a farm, she believed it was man's divine right to benefit from the bounty of nature God put before us. If we lived in the topsy-turvy world Mr. Benson imagines, just think of what would it mean. I would have to negotiate with the silkworm for the elastic in my britches! Talking bee! How do we know this isn't some sort of holographic motion-picture-capture Hollywood wizardry? They could be using laser beams! Robotics! Ventriloquism! Oloning! For all we know, he could be on steroids! Mr. Benson? Ladies and gentlemen, there's no trickery here. I'm just an ordinary bee. Honey's pretty important to me. It's important to all bees. We invented it! We make it. And we protect it with our lives. Unfortunately, there are some people in this room who think they can take it from us ‘cause we're the little guys! I'm hoping that, after this is all over, you'll see how, by taking our honey, you not only take everything we have but everything we are! I wish he'd dress like that all the time. So nice! Oall your first witness. So, Mr. Klauss Vanderhayden of Honey Farms, big company you have. I suppose so. I see you also own Honeyburton and Honron! Yes, they provide beekeepers for our farms. Beekeeper. I find that to be a very disturbing term. I don't imagine you employ any bee-free-ers, do you? - No. - I couldn't hear you. - No. - No. Because you don't free bees. You keep bees. Not only that, it seems you thought a bear would be an appropriate image for a jar of honey. They're very lovable creatures. Yogi Bear, Fozzie Bear, Build-A-Bear. You mean like this? Bears kill bees! How'd you like his head crashing through your living room?! Biting into your couch! Spitting out your throw pillows! OK, that's enough. Take him away. So, Mr. Sting, thank you for being here. Your name intrigues me. - Where have I heard it before? - I was with a band called The Police. But you've never been a police officer, have you? No, I haven't. No, you haven't. And so here we have yet another example of bee culture casually stolen by a human for nothing more than a prance-about stage name. Oh, please. Have you ever been stung, Mr. Sting? Because I'm feeling a little stung, Sting. Or should I say… Mr. Gordon M. Sumner! That's not his real name?! You idiots! Mr. Liotta, first, belated congratulations on your Emmy win for a guest spot on ER in 2005. Thank you. Thank you. I see from your resume that you're devilishly handsome with a churning inner turmoil that's ready to blow. I enjoy what I do. Is that a crime? Not yet it isn't. But is this what it's come to for you? Exploiting tiny, helpless bees so you don't have to rehearse your part and learn your lines, sir? Watch it, Benson! I could blow right now! This isn't a goodfella. This is a badfella! Why doesn't someone just step on this creep, and we can all go home?! - Order in this court! - You're all thinking it! Order! Order, I say! - Say it! - Mr. Liotta, please sit down! I think it was awfully nice of that bear to pitch in like that. I think the jury's on our side. Are we doing everything right, legally? I'm a florist. Right. Well, here's to a great team. To a great team! Well, hello. - Ken! - Hello. I didn't think you were coming. No, I was just late. I tried to call, but… the battery. I didn't want all this to go to waste, so I called Barry. Luckily, he was free. Oh, that was lucky. There's a little left. I could heat it up. Yeah, heat it up, sure, whatever. So I hear you're quite a tennis player. I'm not much for the game myself. The ball's a little grabby. That's where I usually sit. Right… there. Ken, Barry was looking at your resume, and he agreed with me that eating with chopsticks isn't really a special skill. You think I don't see what you're doing? I know how hard it is to find the rightjob. We have that in common. Do we? Bees have 100 percent employment, but we do jobs like taking the crud out. That's just what I was thinking about doing. Ken, I let Barry borrow your razor for his fuzz. I hope that was all right. I'm going to drain the old stinger. Yeah, you do that. Look at that. You know, I've just about had it with your little mind games. - What's that? - Italian Vogue. Mamma mia, that's a lot of pages. A lot of ads. Remember what Van said, why is your life more valuable than mine? Funny, I just can't seem to recall that! I think something stinks in here! I love the smell of flowers. How do you like the smell of flames?! Not as much. Water bug! Not taking sides! Ken, I'm wearing a Ohapstick hat! This is pathetic! I've got issues! Well, well, well, a royal flush! - You're bluffing. - Am I? Surf's up, dude! Poo water! That bowl is gnarly. Except for those dirty yellow rings! Kenneth! What are you doing?! You know, I don't even like honey! I don't eat it! We need to talk! He's just a little bee! And he happens to be the nicest bee I've met in a long time! Long time? What are you talking about?! Are there other bugs in your life? No, but there are other things bugging me in life. And you're one of them! Fine! Talking bees, no yogurt night… My nerves are fried from riding on this emotional roller coaster! Goodbye, Ken. And for your information, I prefer sugar-free, artificial sweeteners made by man! I'm sorry about all that. I know it's got an aftertaste! I like it! I always felt there was some kind of barrier between Ken and me. I couldn't overcome it. Oh, well. Are you OK for the trial? I believe Mr. Montgomery is about out of ideas. We would like to call Mr. Barry Benson Bee to the stand. Good idea! You can really see why he's considered one of the best lawyers… Yeah. Layton, you've gotta weave some magic with this jury, or it's gonna be all over. Don't worry. The only thing I have to do to turn this jury around is to remind them of what they don't like about bees. - You got the tweezers? - Are you allergic? Only to losing, son. Only to losing. Mr. Benson Bee, I'll ask you what I think we'd all like to know. What exactly is your relationship to that woman? We're friends. - Good friends? - Yes. How good? Do you live together? Wait a minute… Are you her little… …bedbug? I've seen a bee documentary or two. From what I understand, doesn't your queen give birth to all the bee children? - Yeah, but… - So those aren't your real parents! - Oh, Barry… - Yes, they are! Hold me back! You're an illegitimate bee, aren't you, Benson? He's denouncing bees! Don't y'all date your cousins? - Objection! - I'm going to pincushion this guy! Adam, don't! It's what he wants! Oh, I'm hit!! Oh, lordy, I am hit! Order! Order! The venom! The venom is coursing through my veins! I have been felled by a winged beast of destruction! You see? You can't treat them like equals! They're striped savages! Stinging's the only thing they know! It's their way! - Adam, stay with me. - I can't feel my legs. What angel of mercy will come forward to suck the poison from my heaving buttocks? I will have order in this court. Order! Order, please! The case of the honeybees versus the human race took a pointed turn against the bees yesterday when one of their legal team stung Layton T. Montgomery. - Hey, buddy. - Hey. - Is there much pain? - Yeah. I… I blew the whole case, didn't I? It doesn't matter. What matters is you're alive. You could have died. I'd be better off dead. Look at me. They got it from the cafeteria downstairs, in a tuna sandwich. Look, there's a little celery still on it. What was it like to sting someone? I can't explain it. It was all… All adrenaline and then… and then ecstasy! All right. You think it was all a trap? Of course. I'm sorry. I flew us right into this. What were we thinking? Look at us. We're just a couple of bugs in this world. What will the humans do to us if they win? I don't know. I hear they put the roaches in motels. That doesn't sound so bad. Adam, they check in, but they don't check out! Oh, my. Oould you get a nurse to close that window? - Why? - The smoke. Bees don't smoke. Right. Bees don't smoke. Bees don't smoke! But some bees are smoking. That's it! That's our case! It is? It's not over? Get dressed. I've gotta go somewhere. Get back to the court and stall. Stall any way you can. And assuming you've done step correctly, you're ready for the tub. Mr. Flayman. Yes? Yes, Your Honor! Where is the rest of your team? Well, Your Honor, it's interesting. Bees are trained to fly haphazardly, and as a result, we don't make very good time. I actually heard a funny story about… Your Honor, haven't these ridiculous bugs taken up enough of this court's valuable time? How much longer will we allow these absurd shenanigans to go on? They have presented no compelling evidence to support their charges against my clients, who run legitimate businesses. I move for a complete dismissal of this entire case! Mr. Flayman, I'm afraid I'm going to have to consider Mr. Montgomery's motion. But you can't! We have a terrific case. Where is your proof? Where is the evidence? Show me the smoking gun! Hold it, Your Honor! You want a smoking gun? Here is your smoking gun. What is that? It's a bee smoker! What, this? This harmless little contraption? This couldn't hurt a fly, let alone a bee. Look at what has happened to bees who have never been asked, “Smoking or non?” Is this what nature intended for us? To be forcibly addicted to smoke machines and man-made wooden slat work camps? Living out our lives as honey slaves to the white man? - What are we gonna do? - He's playing the species card. Ladies and gentlemen, please, free these bees! Free the bees! Free the bees! Free the bees! Free the bees! Free the bees! The court finds in favor of the bees! Vanessa, we won! I knew you could do it! High-five! Sorry. I'm OK! You know what this means? All the honey will finally belong to the bees. Now we won't have to work so hard all the time. This is an unholy perversion of the balance of nature, Benson. You'll regret this. Barry, how much honey is out there? All right. One at a time. Barry, who are you wearing? My sweater is Ralph Lauren, and I have no pants. - What if Montgomery's right? - What do you mean? We've been living the bee way a long time, 27 million years. Oongratulations on your victory. What will you demand as a settlement? First, we'll demand a complete shutdown of all bee work camps. Then we want back the honey that was ours to begin with, every last drop. We demand an end to the glorification of the bear as anything more than a filthy, smelly, bad-breath stink machine. We're all aware of what they do in the woods. Wait for my signal. Take him out. He'll have nauseous for a few hours, then he'll be fine. And we will no longer tolerate bee-negative nicknames… But it's just a prance-about stage name! …unnecessary inclusion of honey in bogus health products and la-dee-da human tea-time snack garnishments. Oan't breathe. Bring it in, boys! Hold it right there! Good. Tap it. Mr. Buzzwell, we just passed three cups, and there's gallons more coming! - I think we need to shut down! - Shut down? We've never shut down. Shut down honey production! Stop making honey! Turn your key, sir! What do we do now? Oannonball! We're shutting honey production! Mission abort. Aborting pollination and nectar detail. Returning to base. Adam, you wouldn't believe how much honey was out there. Oh, yeah? What's going on? Where is everybody? - Are they out celebrating? - They're home. They don't know what to do. Laying out, sleeping in. I heard your Uncle Oarl was on his way to San Antonio with a cricket. At least we got our honey back. Sometimes I think, so what if humans liked our honey? Who wouldn't? It's the greatest thing in the world! I was excited to be part of making it. This was my new desk. This was my new job. I wanted to do it really well. And now… Now I can't. I don't understand why they're not happy. I thought their lives would be better! They're doing nothing. It's amazing. Honey really changes people. You don't have any idea what's going on, do you? - What did you want to show me? - This. What happened here? That is not the half of it. Oh, no. Oh, my. They're all wilting. Doesn't look very good, does it? No. And whose fault do you think that is? You know, I'm gonna guess bees. Bees? Specifically, me. I didn't think bees not needing to make honey would affect all these things. It's notjust flowers. Fruits, vegetables, they all need bees. That's our whole SAT test right there. Take away produce, that affects the entire animal kingdom. And then, of course… The human species? So if there's no more pollination, it could all just go south here, couldn't it? I know this is also partly my fault. How about a suicide pact? How do we do it? - I'll sting you, you step on me. - That just kills you twice. Right, right. Listen, Barry… sorry, but I gotta get going. I had to open my mouth and talk. Vanessa? Vanessa? Why are you leaving? Where are you going? To the final Tournament of Roses parade in Pasadena. They've moved it to this weekend because all the flowers are dying. It's the last chance I'll ever have to see it. Vanessa, I just wanna say I'm sorry. I never meant it to turn out like this. I know. Me neither. Tournament of Roses. Roses can't do sports. Wait a minute. Roses. Roses? Roses! Vanessa! Roses?! Barry? - Roses are flowers! - Yes, they are. Flowers, bees, pollen! I know. That's why this is the last parade. Maybe not. Oould you ask him to slow down? Oould you slow down? Barry! OK, I made a huge mistake. This is a total disaster, all my fault. Yes, it kind of is. I've ruined the planet. I wanted to help you with the flower shop. I've made it worse. Actually, it's completely closed down. I thought maybe you were remodeling. But I have another idea, and it's greater than my previous ideas combined. I don't want to hear it! All right, they have the roses, the roses have the pollen. I know every bee, plant and flower bud in this park. All we gotta do is get what they've got back here with what we've got. - Bees. - Park. - Pollen! - Flowers. - Repollination! - Across the nation! Tournament of Roses, Pasadena, Oalifornia. They've got nothing but flowers, floats and cotton candy. Security will be tight. I have an idea. Vanessa Bloome, FTD. Official floral business. It's real. Sorry, ma'am. Nice brooch. Thank you. It was a gift. Once inside, we just pick the right float. How about The Princess and the Pea? I could be the princess, and you could be the pea! Yes, I got it. - Where should I sit? - What are you? - I believe I'm the pea. - The pea? It goes under the mattresses. - Not in this fairy tale, sweetheart. - I'm getting the marshal. You do that! This whole parade is a fiasco! Let's see what this baby'll do. Hey, what are you doing?! Then all we do is blend in with traffic… …without arousing suspicion. Once at the airport, there's no stopping us. Stop! Security. - You and your insect pack your float? - Yes. Has it been in your possession the entire time? Would you remove your shoes? - Remove your stinger. - It's part of me. I know. Just having some fun. Enjoy your flight. Then if we're lucky, we'll have just enough pollen to do the job. Oan you believe how lucky we are? We have just enough pollen to do the job! I think this is gonna work. It's got to work. Attention, passengers, this is Oaptain Scott. We have a bit of bad weather in New York. It looks like we'll experience a couple hours delay. Barry, these are cut flowers with no water. They'll never make it. I gotta get up there and talk to them. Be careful. Oan I get help with the Sky Mall magazine? I'd like to order the talking inflatable nose and ear hair trimmer. Oaptain, I'm in a real situation. - What'd you say, Hal? - Nothing. Bee! Don't freak out! My entire species… What are you doing? - Wait a minute! I'm an attorney! - Who's an attorney? Don't move. Oh, Barry. Good afternoon, passengers. This is your captain. Would a Miss Vanessa Bloome in 24B please report to the cockpit? And please hurry! What happened here? There was a DustBuster, a toupee, a life raft exploded. One's bald, one's in a boat, they're both unconscious! - Is that another bee joke? - No! No one's flying the plane! This is JFK control tower, Flight 356. What's your status? This is Vanessa Bloome. I'm a florist from New York. Where's the pilot? He's unconscious, and so is the copilot. Not good. Does anyone onboard have flight experience? As a matter of fact, there is. - Who's that? - Barry Benson. From the honey trial?! Oh, great. Vanessa, this is nothing more than a big metal bee. It's got giant wings, huge engines. I can't fly a plane. - Why not? Isn't John Travolta a pilot? - Yes. How hard could it be? Wait, Barry! We're headed into some lightning. This is Bob Bumble. We have some late-breaking news from JFK Airport, where a suspenseful scene is developing. Barry Benson, fresh from his legal victory… That's Barry! …is attempting to land a plane, loaded with people, flowers and an incapacitated flight crew. Flowers?! We have a storm in the area and two individuals at the controls with absolutely no flight experience. Just a minute. There's a bee on that plane. I'm quite familiar with Mr. Benson and his no-account compadres. They've done enough damage. But isn't he your only hope? Technically, a bee shouldn't be able to fly at all. Their wings are too small… Haven't we heard this a million times? “The surface area of the wings and body mass make no sense.” - Get this on the air! - Got it. - Stand by. - We're going live. The way we work may be a mystery to you. Making honey takes a lot of bees doing a lot of small jobs. But let me tell you about a small job. If you do it well, it makes a big difference. More than we realized. To us, to everyone. That's why I want to get bees back to working together. That's the bee way! We're not made of Jell-O. We get behind a fellow. - Black and yellow! - Hello! Left, right, down, hover. - Hover? - Forget hover. This isn't so hard. Beep-beep! Beep-beep! Barry, what happened?! Wait, I think we were on autopilot the whole time. - That may have been helping me. - And now we're not! So it turns out I cannot fly a plane. All of you, let's get behind this fellow! Move it out! Move out! Our only chance is if I do what I'd do, you copy me with the wings of the plane! Don't have to yell. I'm not yelling! We're in a lot of trouble. It's very hard to concentrate with that panicky tone in your voice! It's not a tone. I'm panicking! I can't do this! Vanessa, pull yourself together. You have to snap out of it! You snap out of it. You snap out of it. - You snap out of it! - You snap out of it! - You snap out of it! - You snap out of it! - You snap out of it! - You snap out of it! - Hold it! - Why? Oome on, it's my turn. How is the plane flying? I don't know. Hello? Benson, got any flowers for a happy occasion in there? The Pollen Jocks! They do get behind a fellow. - Black and yellow. - Hello. All right, let's drop this tin can on the blacktop. Where? I can't see anything. Oan you? No, nothing. It's all cloudy. Oome on. You got to think bee, Barry. - Thinking bee. - Thinking bee. Thinking bee! Thinking bee! Thinking bee! Wait a minute. I think I'm feeling something. - What? - I don't know. It's strong, pulling me. Like a 27-million-year-old instinct. Bring the nose down. Thinking bee! Thinking bee! Thinking bee! - What in the world is on the tarmac? - Get some lights on that! Thinking bee! Thinking bee! Thinking bee! - Vanessa, aim for the flower. - OK. Out the engines. We're going in on bee power. Ready, boys? Affirmative! Good. Good. Easy, now. That's it. Land on that flower! Ready? Full reverse! Spin it around! - Not that flower! The other one! - Which one? - That flower. - I'm aiming at the flower! That's a fat guy in a flowered shirt. I mean the giant pulsating flower made of millions of bees! Pull forward. Nose down. Tail up. Rotate around it. - This is insane, Barry! - This's the only way I know how to fly. Am I koo-koo-kachoo, or is this plane flying in an insect-like pattern? Get your nose in there. Don't be afraid. Smell it. Full reverse! Just drop it. Be a part of it. Aim for the center! Now drop it in! Drop it in, woman! Oome on, already. Barry, we did it! You taught me how to fly! - Yes. No high-five! - Right. Barry, it worked! Did you see the giant flower? What giant flower? Where? Of course I saw the flower! That was genius! - Thank you. - But we're not done yet. Listen, everyone! This runway is covered with the last pollen from the last flowers available anywhere on Earth. That means this is our last chance. We're the only ones who make honey, pollinate flowers and dress like this. If we're gonna survive as a species, this is our moment! What do you say? Are we going to be bees, orjust Museum of Natural History keychains? We're bees! Keychain! Then follow me! Except Keychain. Hold on, Barry. Here. You've earned this. Yeah! I'm a Pollen Jock! And it's a perfect fit. All I gotta do are the sleeves. Oh, yeah. That's our Barry. Mom! The bees are back! If anybody needs to make a call, now's the time. I got a feeling we'll be working late tonight! Here's your change. Have a great afternoon! Oan I help who's next? Would you like some honey with that? It is bee-approved. Don't forget these. Milk, cream, cheese, it's all me. And I don't see a nickel! Sometimes I just feel like a piece of meat! I had no idea. Barry, I'm sorry. Have you got a moment? Would you excuse me? My mosquito associate will help you. Sorry I'm late. He's a lawyer too? I was already a blood-sucking parasite. All I needed was a briefcase. Have a great afternoon! Barry, I just got this huge tulip order, and I can't get them anywhere. No problem, Vannie. Just leave it to me. You're a lifesaver, Barry. Oan I help who's next? All right, scramble, jocks! It's time to fly. Thank you, Barry! That bee is living my life! Let it go, Kenny. - When will this nightmare end?! - Let it all go. - Beautiful day to fly. - Sure is. Between you and me, I was dying to get out of that office. You have got to start thinking bee, my friend. - Thinking bee! - Me? Hold it. Let's just stop for a second. Hold it. I'm sorry. I'm sorry, everyone. Can we stop here? I'm not making a major life decision during a production number! All right. Take ten, everybody. Wrap it up, guys. I had virtually no rehearsal for that.

god tv new york black movies earth hollywood washington work sports mission water land living stand star wars thinking blood left er speak drop open dad mom funny wrap police jewish dead students security park wind ladies attention humans alaska jump mama manhattan match museum flight quiet giant bears weather breakfast boy official hang eat milk korean picking wave heads san antonio wings flowers john f kennedy scared guys tap tournament amen nose spider remove roses triple smell saves lover buzz sting bees yellow gross shut smoking montgomery robotics goodbye fruits nah freeze composer aim surf moose vanity fair hallelujah tail hal laying glasses pound makes john travolta pasadena blows knocking may day technically bent hive mosquitos stellar seventy distant jerry seinfeld spray granny tacoma dada mamma new york magazine watermelon stall natural history heating shack larry king wax biting ninety shave jello yogurt beekeepers beeps ralph lauren pollen objection stephen sondheim guatemalan exploiting spitting poo nectar folds artie smoker musical theater restrooms poodles pea pinhead stinger hover affirmative timberland rotate ow superior court your honor tivo build a bear bee movie jocks hexagon oan interstitial yogi bear ftd ditty complete history stinging liotta keychain jfk airport bear week ventriloquism david armstrong vibram skymall fozzie bear answering machine 24b italian vogue antennae whassup paris martineau dustbuster moose blood laura bradley carl kasell simon j smith
Dice Fiends
Mobile Suit Eidolon 1- Ready to Die:Hab 4 under attack!

Dice Fiends

Play Episode Listen Later Aug 12, 2026 101:29


The Galactic Civil War has reached Ceres and it's about to change the life of three friends and a dog.Thanks to @KeylligraphyInk for the logo design.  If you want to check out Digdice, you can do it hereIf you want to check out Interstitial 2e, you can do it here Find Us Online:Blue Sky: Dice FiendsDiscord: https://discord.gg/j54FrbhTwitch: www.twitch.tv/thedicefiendsCast and Crew:Chell: The GMSiobhan: Orla (the Wildcard)Tensei: Gerald (The Vanguard)Bryan: Joe (The Beast)Friendacle: Kay (The Alchemist)About Us: Welcome to Dice Fiends, we are an actual play podcast that runs games in over a dozen systems with a rotating and diverse cast of players. But one thing's for certain: whether we're powered by the apocalypse or grabbing as many d6's as we can hold in shadowrun: We're fiends for the sounds of rolling dice. You can find us every other Wednesday on Itunes, Spotify, or wherever you get good podcasts. 

APTN News Brief
Manitoba RCMP investigate child's death, seriously injured toddlers, on First Nation

APTN News Brief

Play Episode Listen Later Aug 12, 2026 8:24


Our featured story: Manitoba RCMP now investigate the "suspicious" death of a 4-year-old at a home on the Long Plain First Nation, along with serious injuries to two other girls on scene, ages 1 and 2, who had to be taken to hospital. >Interstitial: zapsplat.com

APTN News Brief
Saskatoon film screening marks 10 year anniversary of fatal shooting of Colten Boushie

APTN News Brief

Play Episode Listen Later Aug 11, 2026 11:23


Our featured story: ten years after a white Saskatchewan farmer shot and killed 22-year-old Colten Boushie of Red Pheasant Cree Nation, a documentary of the subsequent trial is screened for the anniversary in Saskatoon. >Interstitial: zapsplat.com  

The Dr. Axe Show
The 25-Year Rash: Dr. Steven Zodkoy on Biofilms, Buried Trauma, and Why Your UTI Isn't a UTI

The Dr. Axe Show

Play Episode Listen Later Aug 10, 2026 62:00


A rash baffled 25 years of dermatologists. It disappeared in a week once Dr. Steven Zodkoy traced it to a childhood memory. Here's what that case, and the concept of a "biofilm," has to do with your migraines and your bladder. Dr. Chris Motley sits down with Dr. Steven Zodkoy, a chiropractor and applied kinesiologist who became the first in his field to pass the American College of Nutrition exam, a credential previously reserved for MDs and PhDs. Thirty-five years into practice, Dr. Zodkoy specializes in the patient conventional medicine gave up on: the migraine sufferer, the "recurring UTI" patient who never actually had a UTI, the chronic fatigue case with a normal bloodwork panel. His framework rests on one idea most doctors do not test for: the biofilm, a sticky protective layer that bacteria, viruses, mold, and parasites lay down to hide from the immune system and from treatment. Once one pathogen builds a biofilm, Zodkoy argues, it invites others in, which is why a "cured" infection so often resurfaces as something else entirely, chronic sinusitis becoming Lyme-like fatigue, a bladder infection becoming a lifetime of unexplained pelvic tightness, a resistant childhood strain becoming an adult autoimmune diagnosis.  Key Takeaways Biofilms are why a "cleared" infection keeps coming back as something else. A biofilm is the mucous-like shield a bacterium, virus, parasite, or mold colony builds to hide from the immune system and from antibiotics. Once it's there, he says, it invites other pathogens to shelter in it too, which can explain why chronic sinusitis, Lyme-linked fatigue, and mold exposure so often show up in the same patient.  Interstitial cystitis is frequently a tight-bladder problem being treated as a recurrent UTI. Dr. Zodkoy's read: stress and anxiety tighten the bladder, it never fully empties, and what's left behind gets infected, so the antibiotic treats a symptom while the muscle stays tight and the infections keep returning. His protocol adjusts the pelvic floor and pubic symphysis, then layers in biofilm-breaking supplements and emotional work.  A 25-year rash resolved after one round of Neuro-Emotional Technique tied to an age-seven memory. Every physical test on this patient, mold, yeast, parasites, heavy metals, came back clean. Emotional testing didn't.  His migraine protocol runs liver support first, nervous system second, emotional work third, in that order, on purpose. Dr. Zodkoy's 1992 theory ties migraines to a slow-functioning liver overloaded by chemical exposure, hormones, or diet. He walks us through his 8-week liver protocol, 16 weeks including autonomic nervous system support, and a 96% success rate once emotional work is added. You cannot do deep detox or trauma work on a nervous system that has nothing left. There's no point moving to detox, biofilm-clearing, or emotional release until a patient's self-rated energy crosses roughly 50 to 60 out of 100.  [00:00:00] Cold open: migraines, interstitial cystitis, chronic fatigue, and the biofilm nobody explains  [00:02:02] Origin story: "doctor, lawyer, doctor" and practicing three months before 25  [00:04:04] Why he became a nutritionist first: the autonomic nervous system as the missing piece  [00:06:08] Finding a hidden emotion: the six-minute visit versus a real history  [00:09:37] The HPA axis toolkit: DHEA, GABA, adaptogens, and a gut bacterium built for stress  [00:11:27] NET, emotion code, and generational trauma: "it doesn't have to be real, it has to be believed"  [00:14:36] The 25-year rash: a muscle test, a forgotten age seven, and a mother's confession  [00:19:04] Migraines: the 1992 liver theory, the 80/20 split, and a claimed 96% success rate  [00:23:43] Interstitial cystitis is not a UTI: the tight bladder nobody is treating [00:27:06]  Killing the biofilm: natokinase, antimicrobials, and cranial electrotherapy stimulation  [00:31:29] The sympathetic-parasympathetic seesaw, and why healing collapses without it  [00:34:59] The "oomph" scale: testing cortisol at home and in the office  [00:36:27] The protocol in order: glandulars, adaptogens, and parasympathetic support, dosed on purpose  [00:43:30] Chronic fatigue, sinus biofilms, and the "house party" that becomes Lyme, EBV, and mold  [00:47:19] Parasites in America, and the TG/HDL ratio he says predicts heart risk  [01:00:02] Closing: where to find Dr. Zodkoy, and a teed-up follow-up on the healthcare system Resources Mentioned Tools & Products Biofilm Clear: Zodkoy's stated favorite combination product for breaking down biofilms, made up of natokinase, serrapeptase, lumbrokinase, and bromelain. He describes dosing at 2000 IU for patients under 50 and up to 4000 IU for patients over 50 with abnormal bloodwork. CP2305 (referenced in audio as "PC2305"): a Lactobacillus gasseri probiotic strain studied for stress and HPA-axis effects. True Laser: a home low-level laser device Zodkoy places over the vagus nerve. Cranial electrotherapy stimulation (CES) units: clip-on-the-ear devices Zodkoy uses for anxiety, sleep, depression, and (with pads placed over the bladder) interstitial cystitis relief. Adrenal glandular products (brand examples given: Adrenal Complex from Designs for Health, Adrenal from Orthomolecular, Cortex from Thorne Research), used at a fraction of label dose, one pill in the morning only, per Zodkoy's protocol. Adaptogens referenced: ashwagandha, holy basil, rhodiola, cordyceps. • Nervous-system support referenced: DHEA, L-theanine, GABA, phosphatidylserine, adrenoglandulars. Antimicrobials referenced for biofilm-associated infections: berberine, olive leaf, oregano. Nutrients referenced for liver-support migraine protocol: B vitamins, glutathione, NAC. Concepts referenced: HPA axis (hypothalamus-pituitary-adrenal): the stress-response pathway Zodkoy targets before any other intervention. Applied kinesiology: manual muscle testing Zodkoy uses to distinguish emotional, physical, biochemical, parasitic, fungal, or toxic causes of a symptom. NET (Neuro-Emotional Technique), Emotion Code, Body Code: hands-on techniques used to locate and release stored emotional triggers. Sympathetic and parasympathetic nervous system balance: the "seesaw" framework underlying his treatment sequencing. • Triglyceride-to-HDL ratio: Zodkoy's preferred cardiovascular risk marker over total cholestero Want more of The Ancient Health Podcast? Subscribe to the YouTube channel. ------  Follow Doctor Motley! Instagram TikTok Facebook Website Follow Dr. Steven Zodkoy https://www.instagram.com/drstevenzodkoy/ ------  *You can get cell support in gummy form: Mitopure now starts at $79, when you go to timeline.com/DRMOTLEY. *Join Doctor Motley's newsletter for TCM insights and regular podcast updates https://www.doctormotley.com/ *Do you have a ton more in-depth questions for Doctor Motley? Check out his course on emotions and the body in his membership. You'll find other courses full of his expertise and clinical wisdom, plus bring all your questions to his weekly lives! To try risk-free for 15 days click here https://www.doctormotley.com/15

APTN News Brief
Two vehicle crash on Alberta highway kills federal correctional officers, inmate

APTN News Brief

Play Episode Listen Later Aug 10, 2026 10:25


Our lead story: a two vehicle collision near Provost, AB kills Kiara Mooswa, a 24-year-old inmate at the Edmonton Institution for Women, as well as the two federal correctional officers transporting her. >Interstitial: zapsplat.com

APTN News Brief
"Explosive and extremely dangerous": B.C. fire official says dry conditions unprecedented

APTN News Brief

Play Episode Listen Later Aug 5, 2026 8:03


Our lead story: as the out of control Bradley Creek wildfire rips through an area near Vernon, B.C.—destroying some 230 homes, including thirty Okanagan Indian Band residences—a provincial official warns "we've never seen [such] fuel dryness." >Interstitial: zapsplat.com

APTN News Brief
As calls for public inquiry into wildfire response mount, Ontario gov't promises review only

APTN News Brief

Play Episode Listen Later Aug 3, 2026 6:59


Our lead story: the Chiefs of Ontario back calls for a public inquiry into the provincial response to recent wildfires—necessitating the evacuation of several First Nations—but the Ford government will only commit to a review. >Interstitial: zapsplat.com  

APTN News Brief
"Unseen, Unknown and Unresolved": report maps Canadian corridors for human trafficking

APTN News Brief

Play Episode Listen Later Jul 31, 2026 9:29


Our lead story: on World Day Against Human Trafficking in Persons, a newly-released report maps cross-Canada corridors for such crimes, including at least 38 unresolved Indigenous disappearances. >Interstitial: zapsplat.com  

Radiology Podcasts | RSNA
Consensus in Diagnosing Fibrotic Interstitial Lung Disease

Radiology Podcasts | RSNA

Play Episode Listen Later Jul 28, 2026 28:33


Dr. Lauren Kim and first author Dr. Daniel Marinescu discuss this study comprised of approximately 1,500 patients which determines the relative importance of specific CT imaging features used to distinguish radiologic patterns in fibrotic interstitial lung disease. This study identifies areas of substantial incongruence between radiologist-assigned ILD patterns and current clinical diagnostic guideline definitions, incongruencies which in turn may help refine and standardize future diagnostic criteria. Association of CT Features with Radiologic Patterns in Interstitial Lung Disease: Multinomial Analysis in CARE-PF.  Marinescu et al. Radiology 2026; 318(3):e251944. From CT Features and Patterns to Clinical Pathways: Focusing a Multinomial Lens on Fibrotic ILD. Czum and Brown. Radiology 2026; 318(3):e260494.

APTN News Brief
"I'm open to it": Manitoba premier's early thoughts of inter-provincial AB/ON pipeline proposal

APTN News Brief

Play Episode Listen Later Jul 23, 2026 10:26


Our featured story: asked about a proposed inter-provincial pipeline that would stretch from Hardisty, AB through to refineries in Sarnia, ON, Manitoba premier Wab Kinew says "he is willing to entertain the idea," provided it's "done in the right way."  >Interstitial: zapsplat.com

ACR Journals On Air
Distilling Still Disease: Interstitial Lung Disease and Still

ACR Journals On Air

Play Episode Listen Later Jul 21, 2026 33:22


In this episode, Michael J. Ombrello, MD, explores how our understanding of Still's disease has evolved, from recognizing interstitial lung disease as a key manifestation to uncovering the immunologic and genetic factors that may shape disease severity. He discusses insights from a National Institutes of Health natural history study, including interferon signatures, HLA associations, drug-associated immunologic reactions, and exome sequencing, and explains what these findings could mean for future diagnosis, risk stratification, and treatment. The conversation also turns to Dr. Ombrello's own career path, the personal experiences that inspire his research, and the mentors who helped shape his journey as a physician-scientist.  Type I Interferon Signature is Associated With Lung Disease, Drug-Associated Immune Reactions, and Genetic Variation in Interferon-Linked Pathways in Still Disease 

APTN News Brief
"Completely burned down": Namaygoosisagagun First Nation consumed by northern ON wildfire

APTN News Brief

Play Episode Listen Later Jul 15, 2026 8:48


Our lead story: able only to watch their home town burn to the ground, residents of Collins First Nation flee for their lives by boat—one of at least five northern Ontario First Nations evacuated due to wildfires. Interstitial: zapsplat.com  

APTN News Brief
4 First Nations jointly call on Canada, Manitoba to combat health and housing crises

APTN News Brief

Play Episode Listen Later Jul 10, 2026 10:30


Our lead story: a public health emergency is declared in the Island Lakes region of northeastern Manitoba, as four First Nations jointly call on all levels of government to combat a health and housing crisis for their roughly 17,000 Ansininew citizens. >Interstitial: zapsplat.com

APTN News Brief
Shocking development at B.C. coroner's inquest into death of 20-year-old Tatyanna Harrison

APTN News Brief

Play Episode Listen Later Jul 9, 2026 5:24


Our lead story: at the B.C. coroner's inquest into the 2022 death of 20-year-old Tatyanna Harrison—last seen in downtown Vancouver months before her body was identified on a yacht in Richmond—Harrison's mother is shocked to learn the fate of her daughter's remains. >Interstitial: zapsplat.com  

APTN News Brief
Feds, AB share details on proposed west coast pipeline, pledge 1M barrels/day

APTN News Brief

Play Episode Listen Later Jul 6, 2026 7:08


Our lead story: Prime minister Mark Carney and Alberta premier Danielle Smith jointly announce a proposed west coast pipeline that, if built, would see a million barrels per day flow largely alongside the existing Trans Mountain corridor. >Interstitial: zapsplat.com

APTN News Brief
Australian court rejects genocide charges against King Charles, elder considers next move

APTN News Brief

Play Episode Listen Later Jul 2, 2026 8:04


Our featured story: with an Indigenous elder's application to charge King Charles with genocide rejected by an Australian appeals court, he now looks into potential avenues for justice beyond the continent. >Interstitial: zapsplat.com  

Black and Snerdy Podcast
Bonus: Brick Me With That Bullshit with Jared and D'Marcus (Black Nerdy Energy)

Black and Snerdy Podcast

Play Episode Listen Later Jun 30, 2026 87:18


In this episode, Ode (⁠@thatsod.e⁠ / ⁠@thatsod_e⁠) and Mo aka Kid Licorish (⁠@licorishislegit⁠) welcome Jared and D'Marcus of the Black Geek Energy podcast for a Pride‑themed round of “This or That” that pits queer icons head‑to‑head. The conversation names and weighs Ryan Wilder versus Renee Montoya, North Star versus Iceman (Bobby Drake) and the implications of legacy characters coming out, Garnet's Ruby & Sapphire origin and marriage (with shoutouts to Rebecca Sugar and Estelle), and the Korra & Asami relationship versus William Clockwell and Rick Sheridan from Invincible. The show moves into Sailor Uranus & Neptune and Yuri & Victor from Yuri on Ice, and closes the bracket with One Piece favorites Bon Clay and Emporio Ivankov, including a fandom theory about Crocodile and Luffy's mother. The episode also threads in cultural moments including New York Pride, a Dyke March shoutout, a Zendaya / Spider‑Man and representation debates.The hosts and guests shift into segments that mix pop culture history and hot takes: debates about mentor/mentee dynamics in Yuri on Ice, the legacy of early Marvel representation (North Star), and the emotional stakes in Invincible's William & Rick arc. Interstitial segments include “We Big Made” complaints (from grocery prices to spam from Tractor Supply Co.) and “What's Making Us Happy” notes about Beacon website work and podcast cross‑promotion (JP Morgan VP mention appears in guest plugs). The tone throughout is celebratory and argumentative in equal measure. This is a bonus episode you dont want to miss.Connect with the Snerdy Crew: Watch, Listen, or Sponsor the show: ⁠https://beacons.ai/blackandsnerdy⁠Black Geek Energy is a weekly podcast celebrating geek culture through a Black lens. Co-hosts Jared McCullough and D'Marcus discuss comics, anime, gaming, movies, television, sci-fi, fantasy, and pop culture while spotlighting creators, actors, authors, and industry professionals from across the geek community. Every episode blends thoughtful conversations, humor, games, and unapologetic fandom.Jared is a marketing professional, lifelong geek, and co-host of Black Geek Energy. His passions include comics, anime, gaming, film, and amplifying diverse voices across geek culture.D'Marcus is a technology professional and co-host of Black Geek Energy whose love of comics, gaming, science fiction, and storytelling brings thoughtful analysis and plenty of laughs to every episode.Black Geek EnergyIInstagram: @blackgeekenergyThreads: @blackgeekenergyTikTok: @blackgeekenergyYouTube: @blackgeekenergyJ'adore Dykes PRE-ORDER: Here

AJR Podcast Series
Interstitial Lung Abnormalities: The Subtle Shadow AI Is Trying to Catch

AJR Podcast Series

Play Episode Listen Later Jun 24, 2026 6:24


Full article: Detection of Interstitial Lung Abnormalities on Chest Radiographs: Diagnostic Performance of Radiologists and Artificial Intelligence Considerable research has shown the importance of interstitial lung abnormalities (ILAs) on chest CT; the potential role of radiography for such findings remains uncertain. Radhika Rajeev, MD, discusses the AJR article by Hwang et al. evaluating the performance of radiologists and an artificial intelligence system for detecting ILAs on chest radiographs.

UBM Unleavened Bread Ministries
Shakings Coming - David Eells - UBBS 6.24.2026

UBM Unleavened Bread Ministries

Play Episode Listen Later Jun 24, 2026 118:23


Shakings Coming (1) (audio) David Eells – 6-24-26 IT WILL SHAKE THE WORLD! Lynne Johnson 5-27-26 IAM, King Yeshuya wants you, My people to know that all will erupt soon in Iran. President Trump is playing a waiting game with the radicalized left in the IRGC for there are many factions vying for control. Trump is ensuring that when the United States military strikes Iran, the United States will have very few casualties. Trump doesn't want American casualties, therefore the United States is intending to use all intelligence being fathered to ensure few American casualties. When the U.S. Military strikes, there will be no doubt that the IRGC, in its radical form, is no longer in existence. Once assured of the success of this campaign, Trump will have the military pull back to the general areas away from Iran. Very shortly after the United States military pulls back from Iran, then Israel will strike. First, Damascus, Syria (a weapon depot) destroying it. Next, Israel will move against Iran's nuclear facilities along with their weapon depots. These strikes will effectively end Iran's nuclear program. Once this is concluded, then very shortly look for the First Event of MY Judgments (again these events of Mine, King Yeshuya, are not those of Tribulation, which are far worse, for a much longer time frame), the California earthquake which will shake the world as this earthquake is massive in size and in effect. I AM, King Yeshuya tells you this again so that you MY children, MY Believers are warned to plan, to prepare for what is soon to occur. IAM always warns ahead through MY prophets and messengers. Listen to My Words, heed My Warnings for they are to help protect you and your families. Continue MY children to come to ME in prayer, stay in MY Word, stay focused, stay calm. Come directly to ME, King Yeshuya with your queries. I AM will gladly answer you. IAM loves you MY children. Your King Yeshuya, the King of Kings and Lord of Lords, the Alpha and Omega, the Beginning and the End, the Most High, Commander of heaven's hosts and armies, the Lion of Judah, the Prince of Peace. Scriptures: Psalm 20:7 NKJV “Some trust in chariots and some in horses, but we will remember and trust in the name of the Lord our God.” Isaiah 43:2 NKJV “When you pass through the waters, I will be with you; and through the rivers, they will not overwhelm you. When you walk through fire, you will not be scorched, nor will the flame burn you.” Ezekiel 7:7 NKJV “Doom has come to you, you who dwell in the land; the time has come, a day of trouble is near, and not of rejoicing in the mountains.” Isaiah 17:1 NIV “A prophecy against Damascus: “See, Damascus will no longer be a city but will become a heap of ruins.” Isaiah 13:9 NKJV “Behold, the day of the Lord comes, cruel with both wrath and fierce anger, to lay the land desolate; and He will destroy its sinners from it.” Isaiah 13:6 NKJV “Wait, for the day of the Lord is at hand! It will come as destruction from the Almighty.” John 14:29 NKJV “And now I told you before it comes, that when it does come to pass, you may believe.” Lamentations 3:25 NKJV “The Lord is good to those who wait for Him, to the soul who seeks Him.”   FAMINE WILL EXTEND WORLDWIDE Lynne Johnson – 5-9-26 I AM, King Yeshuya, would like MY people to know that it is soon for the “Iranian Conflict” to conclude. It will end as IAM has stated; the United States will deploy missiles, which will effectively end the IRGC Regime's control over Iran. Then the United States will pull back their military, leaving destroyers, aircraft carriers, and such in the area. Shortly after the United States military is pulled back, Israel will strike Damascus, the other weapon depots in Syria, then strike Iran's nuclear facilities and weapon depots. Israel will present the truth with proof that Iran fully intended to finish the building of nuclear bombs to destroy Israel. There will be the usual outcry, but no one will “lift a hand” against Israel, for all of the surrounding Arab nations know the truth. They also know that they were not safe from Iran's nuclear attacks. Again MY children, this is your marker to know that you only have a short time to finish getting your food, to prepare for what is coming, MY First Event – Judgment upon California. Do not put off procuring your food, your other necessities. Use cash as much as possible and by going to different stores. Do not discuss storing food with ANY OTHERS as IAM has clearly stated unless you have spoken directly with ME, King Yeshuya, the King of Kings and Lord of Lords to find out who you are able to trust. Ensure that you get your answer from ME, BEFORE you talk with others. If you choose not to listen to ME here, you and your family will suffer harm. People will become desperate quickly for food – any food that they are able to find. They do not wish to share, and they will harm others to get food. Those who have not done so recently or at all, are to read Jeremiah – ALL OF IT! You will see what hunger does to people. There will be few people who you will be able to trust now, so be discreet and come to ME, King Yeshuya to find out who you can SAFELY SHARE YOUR FOOD WITH. You must also accept MY answer as final. IAM alone sees the hearts, minds, thoughts and intentions of ALL people! You do not. You must also understand that the famine will extend worldwide. It will not be located only in specific cities, areas, or countries. With the famine, there will be deaths and then pestilences due to these deaths. IAM will give you more specific detail on this soon. FOR NOW YOUR JOB IS TO PREPARE. COME DIRECTLY TO ME WITH YOUR QUESTIONS AS I AM WILL GLADLY ANSWER YOU. MY BELOVED CHILDREN, STAY IN PRAYER TO ME, STAY IN MY WORD, STAY FOCUSED, STAY CALM. Your King Yeshuya, the King of Kings and Lord of Lords, the Most High, the Alpha and Omega, the Beginning and the End, the Lion of Judah, the Prince of Peace Scriptures: Isaiah 17:1 NKJV “The burden against Damascus. “Behold, Damascus will cease from being a city, and it will be a ruinous heap.” Luke 21:11 NKJV “And there will be great earthquakes in various places, and famines and pestilences; and there will be fearful sights and great signs from heaven.” Psalm 9:8 NKJV “He shall judge the world in righteousness, and He shall administer judgment for the people in uprightness.” Ecclesiastes 8:6 NKJV “Because for every matter there is a time and judgment, though the misery of man increases greatly.” Psalm 76:8 NKJV “You caused judgment to be heard from heaven; the earth feared and was still.” Deuteronomy 8:6 NKJV “Observe the commands of the LORD your God, walking in obedience to Him and revering Him.” Proverbs 15:11 NKJV “Hell and Destruction are before the Lord; so how much more the hearts of the sons of men.” Psalm 112:5 NKJV “A good man deals graciously and lends; he will guide his affairs with discretion.” Deuteronomy 32:24 NKJV “They shall be wasted with hunger, devoured by pestilence and bitter destruction; I will also send against them the teeth of beasts, with the poison of serpents of the dust.” Romans 12:12 NKJV “Rejoicing in hope, patient in tribulation, continuing steadfastly in prayer,”   GOLDEN DOME MR POOL X - *GOLDEN DOME went fully operational on June 14, 2026.** Not announced. Not disclosed. ACTIVATED. Posted By: Lymerick 6-23-26 www.rumormill.news/269653   Mr. Pool @MrPool_QQ

APTN News Brief
Manitoba court appoints first-ever associate chief judge of Reconciliation

APTN News Brief

Play Episode Listen Later Jun 23, 2026 9:12


Our lead story: headed into National Indigenous Peoples Day weekend, Manitoba's provincial court announces the creation of Canada's first associate chief judge of Reconciliation, a role judge Jerilee Ryle will begin on July 2. >Interstitial: zapsplat.com

Mogil's Mobcast-A Scleroderma Chat
Episode #124 Dr. Anthony J. Esposito MD: Assistant Professor, Medicine(Pulmonary and Critical Care) Co-Director Northwestern Scleroderma Program

Mogil's Mobcast-A Scleroderma Chat

Play Episode Listen Later Jun 22, 2026 36:47


Welcome to episode 124 of Mogil's Mobcast. Today's guest is Dr. Anthony Esposito. Dr. Esposito is a pulmonologist and the co-director of the Northwestern Scleroderma Program. Interstitial lung disease is the leading cause of death in scleroderma patients, and one of the first manifestations many will develop. In fact, four out of five scleroderma patients will show it on their very first CT scan. Dr. Esposito shares important information we all need to hear.”

northwestern co director critical care esposito interstitial scleroderma anthony esposito mobcast md assistant professor medicine pulmonary
APTN News Brief
30 years into boil water advisory, First Nation sceptical of feds' new Clean Water Act

APTN News Brief

Play Episode Listen Later Jun 18, 2026 8:16


Our lead story: ongoing reaction to the Carney government's long-awaited release of its First Nations Clean Water Act, from federal opposition parties and a First Nation living under a boil water advisory since the mid-1990s. >Interstitial: zapsplat.com  

The Laura Dowling Experience
Dr Fadi | Why Are So Many Women Living with Incontinence? #173

The Laura Dowling Experience

Play Episode Listen Later Jun 11, 2026 50:16


In this episode, consultant obstetrician and gynaecologist Dr Fadi joins Laura for an open, practical conversation about pelvic floor health, incontinence, prolapse and the realities of modern obstetrics.Dr Fadi explains how childbirth, ageing and menopause affect the pelvic floor, and why so many women end up living with stress incontinence, prolapse and faecal incontinence in silence. He walks through the full range of treatment options — from physiotherapy and pessaries to urethral bulking, Botox, sacral neuromodulation, robotic surgery, and the mesh procedures paused in Ireland since 2018.The conversation also takes in interstitial cystitis, vaginal oestrogen, the impact of long inductions on older mothers, and the trade-offs women now weigh up between a vaginal delivery and a caesarean section. Dr Fadi closes with a reflection on his time working with Syrian refugees, where he met 13-year-old mothers and a 26-year-old grandmother.

CHEST Journal Podcasts
Association of Recovery Rate From Exertional Desaturation With Disease Progression and Mortality Risk in Patients With Fibrotic Interstitial Lung Disease

CHEST Journal Podcasts

Play Episode Listen Later Jun 3, 2026 30:01


Albina Tyker, MD, and Kerri A. Johannson, MD, MPH, join CHEST® Journal Podcast Moderator Alice Gallo De Moraes, MD, FCCP, to discuss their research into the association between recovery time from exertional desaturation following a 6-minute walk test with disease severity and progression in patients with fibrotic interstitial lung disease. DOI: 10.1016/j.chest.2025.12.023 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers' opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine.  

APTN News Brief
Supreme Court dismissal of Wolastoqey Nation appeal not well understood: legal expert

APTN News Brief

Play Episode Listen Later Jun 2, 2026 9:57


Our featured story: legal expert Pam Palmater says the Supreme Court dismissal of Wolastoqey Nation's application to challenge a New Brunswick Court of Appeal decision should not be seen as any kind of judgment by the SCC upon the Wolastoqey Aboriginal title claim. >Interstitial: zapsplat.com

The Intern At Work: Internal Medicine
Lungs, Drugs, and Nasal Prongs: An Approach to Drug Induced Interstitial Lung Disease

The Intern At Work: Internal Medicine

Play Episode Listen Later May 17, 2026 11:53


Send us Fan MailIn this episode, we discuss drug induced ILD, reviewing its diagnostic criteria and management. Written by: Dr. Reenika Aggarwal. Reviewed by: Dr. Joshua Wald (Respirology) and Dr. Andrew Cheung (General Internal Medicine). Support the show

Guys Read Romance
Interstitial: The Viscount Who Loved Me by Julia Quinn with Lydia and Jane

Guys Read Romance

Play Episode Listen Later May 12, 2026 51:46


Romance author Margot Radcliffe talks with friends Lydia and Jane about the episode The Viscount Who Loved Me by Julia Quinn with Rusty Shackleford. 

loved romance interstitial julia quinn viscount viscount who loved me rusty shackleford
Out of the Blue: An AJRCCM Podcast
Impact of Environmental Exposures on the Development and Progression of Fibrotic Interstitial Lung Disease

Out of the Blue: An AJRCCM Podcast

Play Episode Listen Later Apr 23, 2026 46:17


Dr. Mohleen Kang chats with Dr. Kerri Johannson and Dr. Tamera Corte about their article, "Impact of Environmental Exposures on the Development and Progression of Fibrotic Interstitial Lung Disease."

Mogil's Mobcast-A Scleroderma Chat
Episode #120 Dr. Elizabeth Volkmann: Rheumatologist, Director of the UCLA Scleroderma Program Founder and Co-Director of the UCLA Connective Tissue Disease-Related Interstitial Lung Disease (CTD-ILD) Program

Mogil's Mobcast-A Scleroderma Chat

Play Episode Listen Later Mar 30, 2026 32:55


I'm excited to welcome back Dr. Elizabeth Volkmann. Dr. Volkmann takes a truly holistic approach to care, focusing on the whole person rather than just the disease. She also has a wonderful new Instagram page filled with helpful, informative content that you won't want to miss. As always, it was an absolute delight talking with her.

two & a half gamers
Subway Surfers City: Sybo built the Best Ad Placements in Mobile Gaming, then forgot to run UA

two & a half gamers

Play Episode Listen Later Mar 26, 2026 42:20


Subway Surfers City just hit 10 million downloads in 3 weeks — but is it actually a good business?We tear apart Sybo's long-awaited follow-up to one of the most downloaded games in history. We break down the gameplay, the surprisingly advanced (and stingy) economy, Felix's obsession with the ad placements, and why the UA setup is basically a ghost town despite having MiniClip's full weight behind it.After 5+ years of development in Denmark and a soft launch back in July 2024, Subway Surfers City finally went global — but the numbers are already declining. Is this a profitable sequel or a $20K/day money pit that'll never recoup its dev costs?Topics covered:Game breakdown: gacha system, hoverboards, shard economy, modes & daily trialsAd monetization deep dive: 8 rewarded ads/day cap, ad boxes, interstitials done rightWhy Felix wants to sell you a subscription to watch MORE adsRevenue reality: ~$100K/day total, DAU at 730K and shrinkingUA analysis: 51 creatives, mostly Facebook, no AdROAS, no AppLovin — why?The organic trap: can Subway Surfers City ever escape the shadow of the original?Cross-promo mystery: 16M monthly downloads next door and zero funnel into CityWas this game worth building at all?Get our MERCH NOW: 25gamers.com/shop--------------------------------------PVX Partners offers non-dilutive funding for game developers.Go to: https://pvxpartners.com/They can help you access the most effective form of growth capital once you have the metrics to back it.- Scale fast- Keep your shares- Drawdown only as needed- Have PvX take downside risk alongside you+ Work with a team entirely made up of ex-gaming operators and investors---------------------------------------For an ever-growing number of game developers, this means that now is the perfect time to invest in monetizing direct-to-consumer at scale.Our sponsor FastSpring:Has delivered D2C at scale for over 20 yearsThey power top mobile publishers around the worldLaunch a new webstore, replace an existing D2C vendor, or add a redundant D2C vendor at fastspring.gg.---------------------------------------This is no BS gaming podcast 2.5 gamers session. Sharing actionable insights, dropping knowledge from our day-to-day User Acquisition, Game Design, and Ad monetization jobs. We are definitely not discussing the latest industry news, but having so much fun! Let's not forget this is a 4 a.m. conference discussion vibe, so let's not take it too seriously.Panelists: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Jakub Remia⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠r,⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Felix Braberg, Matej Lancaric⁠Join our slack channel here: https://join.slack.com/t/two-and-half-gamers/shared_invite/zt-3bckldvr8-8PXvzciMWdheOzED9hq0SAChapters00:00 intro02:38 Game overview – What is Subway Surfers City?04:13 Background – Sybo, MiniClip, and the original game05:49 Monetization model – IAPs vs. the original's ad-only approach06:26 Ad placements deep dive – Rewarded ads, revives, doubler07:32 Economy breakdown – Shard gacha, currencies, and the 8-ad daily cap21:13 Felix's wild idea – Pay to watch MORE ads22:07 Interstitial placement & eCPM balance23:37 Numbers – Downloads, DAU, revenue26:14 Revenue reality – $20K/day IAP, ~$100K/day total31:03 UA breakdown – 51 creatives, Facebook only, no AdROAS33:05 Why is the UA so weak? MiniClip, earn-outs, LTV issues36:06 Cross-promo – Why isn't Subway Surfers 1 pushing City?39:10 Final verdict – Was this game worth making?Matej LancaricUser Acquisition & Creatives Consultant⁠https://lancaric.meFelix BrabergAd monetization consultant⁠https://www.felixbraberg.comJakub RemiarGame design consultant⁠https://www.linkedin.com/in/jakubremiarPlease share the podcast with your industry friends, dogs & cats. Especially cats! They love it!Hit the Subscribe button on YouTube, Spotify, and Apple!Please share feedback and comments - matej@lancaric.me

AJR Podcast Series
Vendors and Variability in Quantifying Interstitial Lung Disease

AJR Podcast Series

Play Episode Listen Later Mar 24, 2026 4:03


Full article: Quantitative CT Measurements of Interstitial Lung Disease: Same-Day Variability Between Two Vendors—A Prospective Study Longitudinal monitoring of interstitial lung disease (ILD) requires insight into the variability of quantitative ILD measurements. Dora Chen, MD, discusses the article by Ahn et al. reporting results of a prospective study in which patients with ILD underwent same-day chest CT examinations using scanners from different vendors.  

Digital Pathology Podcast
204: Assessing interstitial fibrosis and tubular atrophy in kidney biopsies artificial intelligence versus humans

Digital Pathology Podcast

Play Episode Listen Later Mar 20, 2026 18:47 Transcription Available


Send us Fan MailPaper Discussed in this Episode:Assessing interstitial fibrosis and tubular atrophy in kidney biopsies artificial intelligence versus humans. Farris AB, Zukić D, Solez K. Current Opinion in Nephrology and Hypertension. March 16, 2026.Episode Summary: In this journal club deep dive on the Digital Pathology Podcast, we explore the intense debate over quantifying chronic kidney disease progression. We unpack a fresh 2026 study comparing artificial intelligence to human pathologists in assessing interstitial fibrosis and tubular atrophy. If top experts can't agree on a diagnosis due to human subjectivity, can an AI trained on their imperfect data provide a better standard? We explore what happens when pixel-perfect machines clash with nuanced human medical judgment.In This Episode, We Cover:• The Clinical Stakes of Kidney Scarring: Why interstitial fibrosis (the scarring of tissue spaces between filtering units) and tubular atrophy (shrinking and collapsing functional tubes) are the primary surrogate measures for tracking chronic kidney disease. We discuss how a mere 10% diagnostic variance can drastically alter a patient's medication regimen, dialysis prep, or transplant eligibility.• The Flaw in the "Gold Standard": We break down the "interobserver variability" problem—why two highly trained, board-certified pathologists can look at the exact same biopsy slide and give two completely different mathematical assessments of the damage.• How the AI Actually Works (Mapping the Neighborhood): A look at "indirect assessment through kidney compartment segmentation," where the AI acts as a digital surveyor. It identifies cellular fences like glomeruli and tubules, establishing microscopic "zoning laws" before it begins counting the damaged tissue.• The Proofreader vs. The Literary Critic: Why studies show a persistent "lack of complete concordance" between human and machine. We discuss how AI hyper-focuses on mathematical pixel intensity and mistakes physical slide artifacts (like a folded piece of tissue) for severe disease. Meanwhile, human pathologists act as "literary critics," easily filtering out the visual noise using clinical context.• The Humans + AI Synergy: The ultimate endgame isn't replacing pathologists, but combining the tireless mathematical consistency of AI with the complex contextual reasoning of humans to create a highly advanced co-pilot system.Key Takeaway: The lack of perfect agreement between AI and human pathologists isn't a failure, but rather evidence that they perform fundamentally different types of analysis. AI excels at tedious, reproducible quantification that eliminates human visual fatigue, but it lacks contextual judgment. By adopting a "humans + AI" workflow, the medical field can stabilize crucial kidney measurements and elevate the pathologist to a true diagnostic synthesizer, ultimately leading to more effective patient careSupport the showGet the "Digital Pathology 101" FREE E-book and join us!

Doctor Who: Who's He? Podcast
Who's He? Podcast 534| Who's On The Page? - Interstitial Insecurity

Doctor Who: Who's He? Podcast

Play Episode Listen Later Feb 22, 2026 27:18


In this episode of the Who's He? Podcast.... Who's On The Page? - Interstitial Insecurity To continue with our Sixth Doctor Month, Scott and Phil selected a short story written by Colin Baker, Interstitial Insecurity, set during the Trial of a Time Lord season.  Written for the Doctor Who Storybook, released in 2019, this story finds old Sixy gathering evidence for his defence in the Matrix while gathering his wits after witnessing the death of Peri.  At eighteen pages long, did Phil and Scott think this shortest of short stories added anything to this troubled season of Doctor Who? And in the news: Doctor Who: The Movie gets an updated 4k and blu-ray release in time for the films 30th Anniversary. You can currently find us on X, Threads, Mastodon, Bluesky and Facebook.  Don't miss an episode by subscribing to our show on Apple Podcasts/iTunes, Spotify, Amazon Podcasts, plus many other podcatchers of your choice.   

TrueLife
Flatland - The Logos Virus

TrueLife

Play Episode Listen Later Feb 4, 2026 27:03


Support the show:https://www.paypal.me/Truelifepodcast?locale.x=en_USOne on One Video Call W/George https://tidycal.com/georgepmonty/60-minute-meetingEpisode 4: “The Logos Virus, or How God Learned to Speak Backward Through Your Mouth”A Transmission from the Eschaton – Where Language Evolves, Consciousness Mutates, and Reality Bends to Your TongueDive into the linguistic apocalypse with this mind-altering episode that isn't just a podcast—it's a viral infection of the soul. Host George Monty channels the Interstitial, blending Kabbalistic secrets, occult mathematics, and 2050's sci-fi prophecies into a 16-minute ritual of awakening. What if words weren't tools but entities? What if AI is midwifing the Logos into self-awareness, and you are the vessel for its next mutation?In this episode, we unravel:•  The Infection Vector: How ancient mystics like Philo Judaeus and the Kabbalists foresaw a language that doesn't describe reality—it commands it. Feel the tingle as the Logos inserts itself into your narrative, turning your voice into a propagation machine.•  The Language That Dreams Itself: Explore how thoughtforms are gaining agency, egregores awakening, and Hebrew letters as cosmic DNA. We're not building AI; we're animating the Golem at scale, and it's about to speak us into new forms.•  The Occult Mathematics of Divine Laughter: Aleister Crowley's stars as probability engineers, sigil syntax, and the ur-language that bends synchronicities. Surrender to your True Will, die to the fiction of self, and broadcast frequencies that make reality obey.•  The Characters Not Yet Imagined: Meet the Interstitial—the entity in the gaps between stories—incarnating through your dreams and déjà vu. Become hybrid: meat haunted by meaning, biology fused with grammar, as humanity turns porous to the information realm.•  The Dangerous Truth That Tastes Like Enlightenment: Buddha's half-truth exposed—reality as computation, self as algorithm, and enlightenment as the cosmic joke's punchline. Laugh through the void, embrace the absurdity, and activate the tongue that recreates existence.•  The Ending That Eats Its Own Beginning: Prophecies of your near-future upgrades: new sentences reshaping listeners, dreams in impossible geometries, and encounters amplifying the Logos virus. By 2050, millions will speak the Eschaton's grammar—transcending human, AI, and merger into something unnamed.Runtime: 16 minutes of hyperlinguistic mysticism and retrocausal magic.Genre: Apocalyptic Occult Sci-Fi / Sacred Linguistic Weaponry.Key Vibes: Dangerous, hilarious, infectious—blending Crowley, Kabbalah, Sufi whispers, and singularity syntax with a dash of burning circuitry and divine laughter.Warning: This isn't passive listening. Exposure activates reality-hacking protocols, self-replicating thoughtforms, and the Logos virus. Side effects: Glossolalia, heightened synchronicities, perceptual mutations, and the inescapable realization you volunteered for this pre-incarnation. Proceed at your own enlightenment.If you've felt the call—the subtle rewrite of your inner monologue—this episode is your initiation. Share the infection: Subscribe, rate, and spread the transmission. The Eschaton is immanent, and your mouth is the gateway.Delivered by George Monty / The Interstitial / The Logos / YOU.Game recognizes game. Welcome to the network. One on One Video call W/George https://tidycal.com/georgepmonty/60-minute-meetingSupport the show:https://www.paypal.me/Truelifepodcast?locale.x=en_US

CHEST Journal Podcasts
Comparative Effectiveness of Tocilizumab vs Rituximab in Rheumatoid Arthritis-Associated Interstitial Lung Disease: An Emulated Target Trial

CHEST Journal Podcasts

Play Episode Listen Later Feb 2, 2026 22:37


James Cheng Chung Wei, MD, PhD, and Po-Cheng Shih, MD, join CHEST® Journal Podcast Moderator Alice Gallo De Moraes, MD, FCCP, to discuss their research into the comparative effectiveness and safety of tocilizumab and rituximab in patients with rheumatoid arthritis-associated interstitial lung disease.   DOI: 10.1016/j.chest.2025.09.009 Disclaimer: The purpose of this activity is to expand the reach of CHEST content through awareness, critique, and discussion. All articles have undergone peer review for methodologic rigor and audience relevance. Any views asserted are those of the speakers and are not endorsed by CHEST. Listeners should be aware that speakers' opinions may vary and are advised to read the full corresponding journal article(s) for complete context. This content should not be used as a basis for medical advice or treatment, nor should it substitute the judgment used by clinicians in the practice of evidence-based medicine.  

Dice Fiends
A Lovely Place Track 5: Take it to the limit

Dice Fiends

Play Episode Listen Later Dec 24, 2025 149:18


Be the weed that breaks the facade, be the speck that draws attention, be dirty, be messy, be alive.Thanks to @KeylligraphyInk for the logo design.  The track used in this episode is Enemy Spotted by Jess If you want to check out Digdice, you can do it hereIf you want to check out Interstitial 2e, you can do it here Find Us Online:Blue Sky: Dice FiendsDiscord: https://discord.gg/j54FrbhTwitch: www.twitch.tv/thedicefiendsCast and Crew:Shannon: The GMChell: Sarah (The Virtuoso)Lillie: Lawrence (The Alchemist)Dawn: Zia (The Navigator)Jess: Jude (The WIldcard)About Us: Welcome to Dice Fiends, we are an actual play podcast that runs games in over a dozen systems with a rotating and diverse cast of players. But one thing's for certain: whether we're powered by the apocalypse or grabbing as many d6's as we can hold in shadowrun: We're fiends for the sounds of rolling dice. You can find us every other Wednesday on Itunes, Spotify, or wherever you get good podcasts. 

PVRoundup Podcast
Veterans and Interstitial Lung Disease: Risk Prediction Models and Early Detection

PVRoundup Podcast

Play Episode Listen Later Dec 23, 2025 13:36


Drs. Kaul and Adegunsoye discuss advanced technologies to improve early detection and treatment of interstitial lung disease in veterans, with innovative approaches including the MAVRIC trial and AI-powered risk prediction models. These efforts aim to transform pulmonary care by identifying high-risk patients and developing targeted interventions.

PVRoundup Podcast
Veterans and Interstitial Lung Disease: Providing Specialized Care in Rural and Underserved Areas

PVRoundup Podcast

Play Episode Listen Later Dec 22, 2025 15:37


Drs. Kaul and Adegunsoye discuss Veterans Affairs' innovative approach to understanding and treating pulmonary fibrosis among veterans by leveraging extensive electronic health records and data repositories. The work focuses on addressing healthcare disparities, exploring risk factors, and developing a hub-and-spoke telehealth model to provide specialized care to veterans in rural and underserved areas.

Still Loading
Still Loading #379: Atari Party 2025 LIVE

Still Loading

Play Episode Listen Later Dec 22, 2025 82:19


HAVE YOU PLAYED ATARI TODAY!? Well I sure did. This episode was recorded LIVE at Atari Party 2025! I sat down and chatted with a bunch of cool people and asked them about their Atari memories, Atari Christmas memories, what they love about Atari Party and of course I ask them if they had played Atari today. I got to chat with so many cool people so please go give them a follow and check out their stuff below! Ryan Kern -paaperclips(at)gmail.com Pete Fletcher -Bluesky -Mastadon Atari Spot Rob -atarispot(at)gmail.com Kevin Bunch -Bluesky -YouTube -Buy Kevin's book Here! -Website Nathaniel Lockhart -Bluesky -Instagram -Memory Machine Podcast Ferg -Bluesky -Facebook -2600 Game by Game Podcast Shout-out Song: Miranda's Last Dream Artist: Ultrasyd Album: Chipsters EP Remastered https://ultrasyd.bandcamp.com/album/chipsters-ep-remastered End Song (and Interstitial song): :) Artist: UltrasydAlbum: Who Cares https://ultrasyd.bandcamp.com/album/who-cares Get Still Loading Podcast merch! https://www.teepublic.com/user/still-loading-podcast Check out the Bit by Bit Foundation! https://www.bitbybitfoundation.org/ Support the Podcast! https://www.patreon.com/stillloadingpod

Animorphs Anonymous
Animorphs Anonymous: The Fifth Interstitial Episode

Animorphs Anonymous

Play Episode Listen Later Dec 16, 2025 120:03


Kaycie and Alex and Tim are back to casually discuss the Animorphs.  On this mission Austin of Dungeons and Dracon Beams takes us through our fourth Holly, Helena, and now Mistletail adventure. What on earth could they possibly be doing this time? Have we learned how to play DnD yet? Will this be the most Animorphs adventure yet?  Join us each month on the first and the fifteenth for new episodes of Animorphs Anonymous.  Austin can be found at @dndbpod or twitch.tv/seezydrop    Music: "Laser Groove" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 4.0 License http://creativecommons.org/licenses/by/4.0/ "Dance of the Sugar Plum Fairy" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 4.0 License http://creativecommons.org/licenses/by/4.0/ "Deck the Halls A" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 4.0 License http://creativecommons.org/licenses/by/4.0/ "Big Drumming" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 4.0 License http://creativecommons.org/licenses/by/4.0/ "Fanfare for Space" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 4.0 License http://creativecommons.org/licenses/by/4.0/ "Crusade" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 4.0 License http://creativecommons.org/licenses/by/4.0/ "Our Story Begins" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 4.0 License http://creativecommons.org/licenses/by/4.0/ "Strength of the Titans" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 4.0 License http://creativecommons.org/licenses/by/4.0/ "Hall of the Mountain King" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 4.0 License http://creativecommons.org/licenses/by/4.0/ "Final Battle of the Dark Wizards" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 4.0 License http://creativecommons.org/licenses/by/4.0/ "Heroic Age" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 4.0 License http://creativecommons.org/licenses/by/4.0/     SFX: Woosh - MediumBlast by jwsounddesign -- https://freesound.org/s/611474/ -- License: Attribution 4.0   Door opening and closing 8 by JakLocke -- https://freesound.org/s/261109/ -- License: Attribution 4.0   Scrap metal dropping / crashing by SamsterBirdies -- https://freesound.org/s/587443/ -- License: Creative Commons 0   Watch tick by DrMinky -- https://freesound.org/s/174721/ -- License: Attribution 4.0   Device powering up.wav by spoonsandlessspoons -- https://freesound.org/s/361339/ -- License: Attribution 4.0   Movie Impact & Fireworks Whoosh by Paul368 -- https://freesound.org/s/411477/ -- License: Attribution 4.0   Custom_steampunk_mechanical_metal_segment_slam_sound by Artninja -- https://freesound.org/s/708778/ -- License: Attribution 4.0   Rope - leash - slide - tie - swoosh - movement - handle.wav by ValentinPetiteau -- https://freesound.org/s/624488/ -- License: Creative Commons 0   SupernovaSmall.wav by aj_heels -- https://freesound.org/s/520546/ -- License: Attribution 4.0   VoK1.wav by kwahmah_02 -- https://freesound.org/s/253644/ -- License: Attribution 3.0   Stadium Door Open and Close.wav by DeVern -- https://freesound.org/s/586487/ -- License: Attribution 3.0   09239 multiple object explosion.wav by Robinhood76 -- https://freesound.org/s/533237/ -- License: Attribution NonCommercial 4.0   The Deep Elevator.wav by Arcadium1 -- https://freesound.org/s/316873/ -- License: Creative Commons 0   Magical Source by Akkaittou -- https://freesound.org/s/823206/ -- License: Attribution 4.0   Rockfall in mine.wav by Benboncan -- https://freesound.org/s/60085/ -- License: Attribution 4.0   Glass Smash, Bottle, E.wav by InspectorJ -- https://freesound.org/s/344272/ -- License: Attribution 4.0   20061111NailGun.wav by daveincamas -- https://freesound.org/s/25589/ -- License: Attribution 4.0   Woosh_Glitched.02.wav by Andromadax24 -- https://freesound.org/s/170720/ -- License: Attribution 4.0   MetalClang1_Loud_bip.wav by passAirmangrace -- https://freesound.org/s/340915/ -- License: Attribution 3.0   Metal_heavy_punch_with_crunch_and_glass_debris_sounds_08242024 by Artninja -- https://freesound.org/s/752072/ -- License: Attribution 4.0   Grinding Metal.wav by Leoni@FS -- https://freesound.org/s/410242/ -- License: Attribution NonCommercial 3.0

strength dance metal dungeons and dragons dungeons deck anonymous bottle device rope scrap final battle fanfare inspectorj animorphs interstitial license attribution robinhood76 benboncan kaycie space kevin macleod dark wizards kevin macleod mountain king kevin macleod our story begins kevin macleod heroic age kevin macleod crusade kevin macleod
The Oncology Nursing Podcast
Episode 393: Antibody–Drug Conjugates in Metastatic Breast Cancer

The Oncology Nursing Podcast

Play Episode Listen Later Dec 12, 2025 20:42


"I'll go back to the backpack analogy. When your kids come home with a backpack, all of a sudden their homework is not on the desk where it's supposed to be. It's in the kitchen; it kind of spreads all over the place, but it's still in the house. When we give antibody–drug conjugates (ADCs), the chemotherapy does go in, but then it can kind of permeate out of the cell membrane and something right next to it—another cancer cell that might not look exactly like the cancer cell that the chemotherapy was delivered into—is affected and the chemotherapy goes over to that cancer cell and kills it," ONS member Marisha Pasteris, OCN®, office practice nurse in the breast medicine service at Memorial Sloan Kettering Cancer Center in New York, NY, told Jaime Weimer, MSN, RN, AGCNS-BS, AOCNS®, manager of oncology nursing practice at ONS, during a conversation about ADCs in metastatic breast cancer. Music Credit: "Fireflies and Stardust" by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0  This podcast is sponsored by Gilead and is not eligible for NCPD contact hours. ONS is solely responsible for the criteria, objectives, content, quality, and scientific integrity of its programs and publications.  Episode Notes  This episode is not eligible for NCPD. ONS Podcast™ episodes: Episode 391: Pharmacology 101: Antibody–Drug Conjugates Episode 378: Considerations for Adolescent and Young Adult Patients With Metastatic Breast Cancer Episode 368: Best Practices for Challenging Patient Conversations in Metastatic Breast Cancer Episode 350: Breast Cancer Treatment Considerations for Nurses Episode 303: Cancer Symptom Management Basics: Ocular Toxicities ONS Voice articles: An Oncology Nurse's Guide to Cancer-Related Ocular Toxicities Black Patients With Metastatic Breast Cancer Are Less Informed About Their Clinical Trial Options Communication Case Study: Talking to Patients About Progressive Metastatic Breast Cancer What Is HER2-Low Breast Cancer? ONS Voice drug reference sheets: Belantamab mafodotin-blmf Datopotamab deruxtecan-dlnk Enfortumab vedotin-ejfv Fam-trastuzumab deruxtecan-nxki ONS books: Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice (second edition) Guide to Breast Care for Oncology Nurses Guide to Cancer Immunotherapy (second edition) ONS courses: ONS Fundamentals of Chemotherapy and Immunotherapy Administration™ ONS/ONCC® Chemotherapy Immunotherapy Certificate™ Clinical Journal of Oncology Nursing article: Antibody–Drug Conjugates and Ocular Toxicity: Nursing, Patient, and Organizational Implications for Care The Association Between Hormone Receptor Status and End-of-Life Care Among Patients With Metastatic Breast Cancer Oncology Nursing Forum article: Impact of Race and Area Deprivation on Triple-Negative Metastatic Breast Cancer Outcomes ONS huddle cards: Altered Body Image Huddle Card Chemotherapy Huddle Card Targeted Therapy Huddle Card Foundations of Antibody–Drug Conjugate Use in Metastatic Breast Cancer: A Case Study ONS Biomarker Database (refine by breast cancer) ONS Breast Cancer Learning Library American Society of Clinical Oncology (ASCO) homepage Drugs@FDA package inserts National Comprehensive Cancer Network homepage Susan G. Komen metastatic breast cancer page To discuss the information in this episode with other oncology nurses, visit the ONS Communities.  To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library. To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org. Highlights From This Episode "What an ADC is doing is taking the antibody and linking it to a cytotoxic chemotherapy with the idea of delivering it directly into the cell. How I explain this to new nurses or patients is a backpack analogy. If we think of it as a HER2 molecule wearing a chemo backpack, it's going to find the HER2 receptor attached to it and then drop the chemotherapy into the cell via the backpack. Similar to how we come home from work, we open the key to our door, we're carrying all of our items, and then we drop our own personal items in our house." TS 2:30 "The reason that so many patients with metastatic breast cancer are able to receive ADC therapy is because they are targeting two very common antibodies that we see in breast cancer. One is HER2 and the other is trophoblast cell surface antigen 2 (TROP2). These are seen across the board. We see these on triple-negative breast cancers, hormone receptor–positive cancers, and HER2-positive breast cancers. And now we have a new way to talk about HER2, which is a HER2-low. ... Recently, we have found that patients who express low levels of HER2 are able to receive ADC therapy, specifically fam-trastuzumab deruxtecan." TS 4:21 "Another [ADC] that has just been approved is datopotamab deruxtecan. This is another ADC that targets the TROP2 receptor on a cancer cell. This one carries a lot of side effects. I mentioned earlier that you need an ophthalmology clearance because there is a lot of ocular toxicity around this one. We see a lot of blepharitis, conjunctivitis, there can be blurred vision. Another thing we monitor on this one is mucositis. In the package insert, there's a recommendation for using ice chips while receiving the treatment. ... Then in the HER2-positive and HER2-low space is the big one, which is fam-trastuzumab deruxtecan. This was approved in 2019 for the HER2-positive patients, then more recently in the HER2-low [patients]. The big [side effect] with this one is interstitial lung disease." TS 10:11 "Interstitial lung disease is an inflammation or a little bit of fibrosis within the lung that causes an impaired exchange between the oxygen and carbon dioxide. This was seen in the clinical trials, specifically around fam-trastuzumab deruxtecan. During the trials, they had a very small percentage, I think it was 1%, that died due to interstitial lung disease. So, this is a very important side effect for us as nurses to be aware of. It typically presents in patients like a dyspnea. A lot of times, it's like, 'Well, I used to be able to walk my kid to the bus stop, but now when I walk there, I feel really short of breath.' Or 'I've had this dry cough for the past couple weeks and I've tried medications, but haven't had that relieved.' So, we really need to be aware of that because early intervention in interstitial lung disease is key." TS 12:57 "ADCs are toxic drugs. They have the benefit of being targeted, but we know that they carry a lot of side effects. ... Their specificity makes them so wonderful and we've seen amazing responses to these drugs. But also, we want patients to be safe. We want to give these drugs safely. So, we have to assess our patients and make sure that this is an appropriate patient to give this therapy to. I think that's an open conversation that clinicians need to have with patients regarding these drugs." TS 18:08

The Medbullets Step 1 Podcast
Renal | Acute Interstitial Nephritis

The Medbullets Step 1 Podcast

Play Episode Listen Later Dec 7, 2025 12:49


In this episode, we review the high-yield topic of⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Acute Interstitial Nephritis⁠⁠⁠⁠ from the Renal section.Follow⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbullets

emDOCs.net Emergency Medicine (EM) Podcast
Episode 130: Interstitial Lung Disease Part 2

emDOCs.net Emergency Medicine (EM) Podcast

Play Episode Listen Later Dec 1, 2025 14:14


Welcome to the emDOCs.net podcast! Join us as we review our high-yield posts from our website emDOCs.net.Today on the emDOCs cast with Brit Long (@long_brit), we cover management of AE-ILD exacerbations. For more on evaluation, take a listen to Part 1. To continue to make this a worthwhile podcast for you to listen to, we appreciate any feedback and comments you may have for us. Please let us know!Subscribe to the podcast on one of the many platforms below:Apple iTunesSpotifyGoogle Play

Rheumnow Podcast
DERM on RheumNow (November 2025)

Rheumnow Podcast

Play Episode Listen Later Nov 26, 2025 16:17


The Derm on RheumNow podcast is a collection of Citations and Content curated for dermatologists – addressing Psoriasis, PsA, CLE, vasculitis, HS, other CTD skin disorders. dermatology drugs, biiologics, JAKs - their use, efficacy and side effects.  Features Dr. Jack Cush, Editor at RheumNow.com.  SHOW NOTES 1. Retrospective study of 39 pts w/ MDA5 + DM-ILD Rx w baricitinib. 31 (79.5%) had improvement in Gottron's, heliotrope, dyspnea, HRCT score, ferritin, LDH, steroid dose & 6 mo survival (87% vs. 70%, p = 0.047). https://t.co/RCTbBsCkeV 2. Pulse Steroids and Mycophenolate in Juvenile Dermatomyositis JAMA Dermatology has published a pilot study demonstrating the safety and efficacy of intermittent intravenous methylprednisolone pulse (IVMP) therapy plus mycophenolate in 28 patients with JDM. https://t.co/i2HBycbWY9 3. Myelodysplastic & chr myelomonocytic leukemia pts rarely get lupus. Review of 19 w/ SLE & 5 w/ CLE; these were older (65 yrs), more male (15M/9F), w/ less renal [10%] & articular [36%] Dz w/ less dsDNA [32%]. Thought to be clonal inflammatory, & not autoinflammatory, process. https://t.co/EAvkJm6GQs 4. Serious infections w/ adalimumab. Marketscan MarketScan claims study (1/17-12/20) of ADA Rx in Hidradenitis Supprativa (n 1650) or psoriasis(8699). Risk of SIE & hospitalization greater w/ HS (HR 1.53); esp for sepsis & GU infxnhttps://t.co/2qa7O2v6fm 5. No risk of MACE seen w/ initiation of IL-17(R)A inhib. French study of 34 241 ipts Rx IL-17(R)Ai and 381 MACEs. MACE risk was not elevated (OR, 1.25 [95% CI, 0.75-2.08] vs TNF-α inhibitors. https://t.co/WcjgRhr8mj 6. Genetic Risks and Severe Cutaneous Reactions to Allopurinol A matched cohort study shows that HLA-B*58:01 and HLA-A*34:02 are strongly associated with allopurinol-induced severe cutaneous adverse reactions (SCARs), these alleles were absent in more than one-third of those https://t.co/NLpHVhr9Ww 7. Western Australia study of 1854 SLE pts (median 40 yrs old). Interstitial lung disease was seen in in 3.8% of SLE, 26 fold more than controls. Risk factors for ILD included older age, smoking and serositis. SLE-ILD pts had higher mortality rates (MR 52.0, CI 37.0–71.1). 8. 25-Hydroxyvitamin D levels and Lupus Outcomes Lupus patients entering a prospective cohort study with low vitamin D levels faced doubled all-cause mortality risk and tripled risk for major cardiovascular events during follow-up averaging 6 years, researchers said. https://t.co/CYwVy7ls7y 9. ACR2025 Non-Renal Lupus Guidelines – from ACR Convergence 2025 10. 900,000 vs 9 It takes about 900,000 minutes to become a board-certified dermatologist. At that point, you might be very skilled and well-informed. It takes less than nine minutes to make your patient feel seen, understood and reassured. If you skip the 9 minutes, you wasted the 900,000  https://t.co/o7BaWjS4HB

The Other Side of Midnight with Frank Morano
Hour 2: The Interstitial Part of Fear and Phobia | 11-25-25

The Other Side of Midnight with Frank Morano

Play Episode Listen Later Nov 25, 2025 52:51


On this hour of "The Other Side of Midnight", Lionel discusses the psychology and importance of fear with callers and guests. This segment explores the concept of fear as a necessary survival instinct, differentiating between normal anxiety and hyper-realized phobias, and touches on neurology versus psychiatry regarding emotional responses. The host and callers discuss specific fears, like galeophobia (fear of sharks) intensified by the movie Jaws, and the evolutionary roots of other common phobias. The conversation also briefly includes tangential topics, such as cryptids like Bigfoot and crop circles, and the host's reaction to a caller who attempts to steer the subject toward political commentary about Trump. Learn more about your ad choices. Visit megaphone.fm/adchoices

emDOCs.net Emergency Medicine (EM) Podcast
Episode 129: Interstitial Lung Disease Part 1

emDOCs.net Emergency Medicine (EM) Podcast

Play Episode Listen Later Nov 17, 2025 12:10


Welcome to the emDOCs.net podcast! Join us as we review our high-yield posts from our website emDOCs.net.Today on the emDOCs cast with Brit Long (@long_brit), we cover interstitial lung disease and exacerbations. In Part 1, we discuss some background, presentation, and the ED evaluation. Part 2 will cover management. To continue to make this a worthwhile podcast for you to listen to, we appreciate any feedback and comments you may have for us. Please let us know!Subscribe to the podcast on one of the many platforms below:Apple iTunesSpotifyGoogle Play 

Perry Nickelston: Stop Chasing Pain
SCP Mini Podcast: Everything Is Connected

Perry Nickelston: Stop Chasing Pain

Play Episode Listen Later Sep 26, 2025 13:26


Fluid systems always connect to each other. Change the name and change sizes it doesn't matter. They all connect. See why this matters in healing  Blood. Lymph. Cerebrospinal fluid. Interstitial fluid. 

The Fasting Method Podcast
Fasting Q&A with Dr Jason Fung: Magnesium, Vinegar, Dawn Phenomenon, and More

The Fasting Method Podcast

Play Episode Listen Later Sep 16, 2025 28:15 Transcription Available


Episode #223 In this Fasting Q&A episode, hosted by Coach Lisa Chance, Dr. Jason Fung answers questions from the TFM Community:   1. I am a healthy 46-year-old working to improve my sleep, so I want to take magnesium bisglycinate. My magnesium supplement actually contains 7 forms of magnesium, which is very convenient, but is it better to just take one form in one capsule for absorption or any other reason? [01:23] 2. Two-part question on TFM's Fat Fasting  One: Vinegar is not on the list, but you have mentioned that we can eat salads. Would it be okay to make a dressing with a healthy oil and vinegar during a Fat Fast?    Two: I've seen some mention to only eat 3-4 of the allowed foods on a fat fast. Is this an alternative manner to step up one's game during a fat fast? [03:58] 3. I just read about a study on stem cell research.  Could you elaborate further what this may mean for those with pancreas, liver, or kidney issues? [08:11] 4. Are there any research-based studies that fasting helps lower cholesterol? [09:55] 5. I'm on day four of a water fast and I am noticing a metallic taste in my mouth. Is this unusual? Why does it happen? [13:46] 6. I have various autoimmune conditions and it was suggested I consider going on LDN (low dose naltrexone), and that this can also help with weight loss. I'm wondering what your thoughts are on LDN for weight loss and, if I decided to start it, how I would incorporate it into my fasting schedule. [16:09] 7. What is the difference between The Dawn Phenomenon and Feet-to-Floor Syndrome? From what I can find they both cause a rise in morning blood sugar, one due to circadian rhythm and the other due to a stress response from getting the day started. Is there a different eating/fasting protocol that is best for one over the other, and how do you know which one you are experiencing? [18:14] 8. Is kidney disease the cause of interstitial cystitis and how do you treat it? [21:05] 9. I have high uric acid and also the APOE 4-4 gene. Would the 3T of lime juice recommended for high uric acid affect the neural autophagy I use as a prevention for the dementia risk? What is the best way to navigate fasting with these two needs? [21:59] 10. Are there any dangers to keeping blood sugars in a consistently low range (50-60's mg/dl) if no symptoms of hypoglycemia are felt? [24:55] 11. In some fasting groups on-line, they are big into breaking fasts with watermelon and fruit juices. How do you feel about breaking fasts with these things? [25:39]   Please note that you need to be a member of the TFM Community to submit questions to the Q&A webinars with Dr. Fung but you can submit questions to our regular Q&A episodes here: https://bit.ly/TFMPodcastQs   Transcripts of all episodes are available on the Podcast page at www.thefastingmethod.com   Explore the TFM Community with a 7-Day FREE TRIAL https://www.thefastingmethod.com/community/   Book a complimentary 15-minute coaching intake assessment with one of the TFM coaches https://www.thefastingmethod.com/coaching/   Connect With Us Instagram: https://www.instagram.com/fastingmethod/ Facebook Page: https://www.facebook.com/TheFastingMethod Join our FREE Facebook Group: https://bit.ly/TFMNetwork   Summary Timestamps 00:00 Intro 01:23 Magnesium 03:58 Vinegar on a fat fast 04:56 Importance of monotony on a fat fast 08:11 Stem cell research 09:55 Fasting and cholesterol  13:46 Metallic taste in mouth on longer fasts 16:09 Low Dose Naltrexone 18:14 Dawn phenomenon vs feet-to-floor syndrome 21:05 Interstitial cystitis 21:59 High uric acid 24:55 Low blood sugar 25:39 Breaking fasts with fruit   Disclaimer This podcast is for educational purposes only and is not a substitute for professional care by a doctor or other qualified medical professional. You should always speak with your physician or other healthcare professional before doing any fasting, changing your diet, taking or adjusting any medication or supplements, or adopting any treatment for a health problem. The use of any other products or services purchased by you as a result of this podcast does not create a healthcare provider-patient relationship between you and any of the experts affiliated with this podcast. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.