Solving the Puzzle with Dr. Datis Kharrazian

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Solving the Puzzle with Dr. Datis Kharrazian is based on more than 20 years of Dr. Kharrazian's experience working with autoimmune and brain health patients throughout the U.S. and Europe, exhaustive review of the scientific research, and protocols he has

Datis Kharrazian, PhD, DHSc, DC, MS, MMSc, FACN


    • May 6, 2025 LATEST EPISODE
    • monthly NEW EPISODES
    • 50m AVG DURATION
    • 50 EPISODES

    Ivy Insights

    The Solving the Puzzle with Dr. Datis Kharrazian podcast is an incredibly informative and helpful resource for individuals seeking to gain a deeper understanding of their health issues and find ways to improve their well-being. Dr. Datis Kharrazian, through his extensive knowledge and expertise in functional medicine, provides listeners with valuable insights on various topics such as causes, symptoms, testing, and remedies for a wide range of health conditions.

    One of the best aspects of this podcast is Dr. Kharrazian's ability to explain complex medical concepts in a simple and easy-to-understand manner. His explanations are clear, concise, and accessible to both healthcare professionals and individuals without a medical background. This makes the information presented in the podcast highly relatable and applicable to everyday life.

    Another great aspect of the podcast is the emphasis on addressing root causes rather than just treating symptoms. Dr. Kharrazian explores the underlying factors that contribute to different health conditions, allowing listeners to gain a deeper understanding of why they may be experiencing certain symptoms or problems. This approach empowers individuals to take control of their own health by addressing the underlying causes rather than simply relying on medications or quick fixes.

    However, one potential drawback of this podcast is that it may not cater to everyone's specific health concerns or interests. While Dr. Kharrazian covers a wide range of topics, there may be some individuals who are seeking information on more specialized or niche areas within functional medicine. It would be beneficial if the podcast could occasionally delve into these specific areas to provide even more comprehensive coverage.

    In conclusion, The Solving the Puzzle with Dr. Datis Kharrazian podcast is an invaluable resource for anyone looking to gain a deeper understanding of their health and explore natural approaches to improving well-being. Dr. Kharrazian's ability to explain complex medical concepts in a simple and relatable way sets this podcast apart from others in the field. Although it may not cover every specialized topic, the podcast provides a solid foundation of knowledge and guidance for individuals on their health journeys.



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    Latest episodes from Solving the Puzzle with Dr. Datis Kharrazian

    Episode 50: The Role of Relationships and Support in Managing Autoimmunity

    Play Episode Listen Later May 6, 2025 75:49


    In this episode, we dive into the environmental and lifestyle factors that impact autoimmunity. From evaluating case reviews to understanding the significance of relationships, stress, and sleep, we explore how these elements shape autoimmune diseases. Discover how proper lifestyle medicine is crucial, and why it's more than just about supplements. Learn about sleep disorders, chemical exposures, and the role of circadian rhythms in modulating the immune system. For more details, visit drknews.com.For patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 Patient Screening and Case Review Process07:55 Sleep's Impact on Immune Function11:27 Rheumatoid Arthritis: Sleep's Vital Role16:15 Stress, Autoimmunity, and IL-17 Dynamics22:13 Exercise & Autoimmunity: Personalized Approach26:57 Chemical Bio-Transformation: Can vs. Can't31:17 Chemical Sensitivity and Immune Response37:45 BPA Study on Autoimmunity Impact44:16 "Identifying Active Heavy Metal Exposure"50:48 Chemical & Immune Tolerance Issues54:42 Avoiding Challenge Tests: Prioritize Immune Reactivity01:01:47 Optimizing Liver Detox and Nutrition01:06:54 Glutathione Protocol for Heavy Metals01:11:03 Glutathione Inhalation for Lung Health01:14:38 Dr. Kharrazian Podcast ResourcesSupport this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

    Episode 49: Navigating Parasitic Infections

    Play Episode Listen Later Feb 10, 2025 86:17


    In this episode of "Solving the Puzzle with Dr. Datis Kharrazian," we dive into the intricate world of gastrointestinal health, focusing specifically on the common pathogen Helicobacter pylori (H. pylori) and various parasites affecting the human body. Dr. Kharrazian as explores the pathophysiological mechanisms of these infections, their clinical presentations, and the potential systemic health issues they can trigger, including autoimmune diseases, cardiovascular risks, and gastrointestinal disturbances. Learn more at drknews.comFor patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 H. Pylori Pathogenesis Explained05:45 H. Pylori: Symptoms and Risks11:58 H. Pylori's Broad Health Impact19:24 Urea Breath Test for H. Pylori25:40 Digestive Health Supplement Strategies32:05 Malaria Symptoms and Transmission Overview36:49 Dormant Malaria Parasite Reactivation39:24 Asymptomatic Malaria: Hidden Transmission Risk46:07 Parasite Transmission Via Poor Hygiene51:12 Deworming Benefits for HIV Patients57:24 Mixed Results in Autoimmune Disease Treatment01:04:05 "Chronic Infections and Immune Function"01:06:46 Sleep's Role in Immunity01:14:47 Bile Acids: Key Immune Regulators01:21:25 Mucosal Immunity and Microbiome Health01:22:37 Factors Affecting Microbiome DiversitySupport this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

    Episode 48: Neurological Health and Interventions with Randy Vawdry

    Play Episode Listen Later Feb 7, 2025 40:05


    Welcome to Solving the Puzzle with Dr. Datis Kharrazian. In today's episode, we are joined by Randy Vawdry, a respected nurse practitioner who has carved a niche in the realm of complex medicine. With a vast background ranging from nursing home care to urgent care, Randy brings a wealth of practical experience to our discussion. We'll dive into his innovative approaches to neurological health, exploring how metabolic health, hormone optimization, and understanding traumatic brain injuries can revolutionize patient care. Randy shares invaluable insights from his clinical practice and educational endeavors, shedding light on how practitioners can master the complexities of brain health to improve outcomes for themselves, their patients, and even their loved ones.Learn more at drknews.comFor patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 Master Class with Expert Clinician04:26 Optimizing Neurological Health Priorities06:35 Value of Mastering Functional Medicine10:16 Prioritize Brain Health for Practitioners13:18 Simplifying Complex Concepts17:40 Lifestyle Medicine and Hormone Optimization20:41 Rethinking Functional Medicine Approach24:35 Functional Medicine's Inexperience Problem28:33 "Symptoms Are the Disease"29:17 Lifestyle Choices and Alzheimer's Prevention33:59 "Promoting Continuous Glucose Monitoring"37:19 Master Class on Neurological Care39:27 Podcast Disclaimer and Dr. Karazigan's DisclosuresSupport this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

    Episode 47: Chronic Lyme Disease and Mold Illnesses

    Play Episode Listen Later Jan 4, 2025 55:11


    This episode dives into the complex world of chronic infections, with a particular focus on the far-reaching impacts of Lyme disease and mold-related illnesses. We explore the debilitating symptoms of chronic Lyme disease, from severe fatigue and chronic joint pain to the potential for neurological damage and heart complications. Our discussion highlights the often-misunderstood overlap between ongoing infections and autoimmune responses, revealing how mismanagement of Lyme can lead to persistent health challenges. Mold illness and mycotoxins are also discussed.Learn more at drknews.comFor patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 Ticks must be removed quickly to prevent Lyme.03:13 Bull's-eye rash indicates Lyme disease; treat immediately.08:29 Chronic Lyme disease severely impacts daily functioning.10:31 Lyme disease disrupts metabolism, causing persistent symptoms.16:05 Infection triggers lasting brain inflammation, causing issues.17:06 Bacteria location influences Lyme disease symptoms severity.20:19 Post Lyme syndrome involves neurological autoimmune issues.25:21 Chronic Lyme impacts include autoimmunity, microbiome issues.29:01 Mold triggers allergies; toxic mold releases mycotoxins.33:14 Sensitivity to mold varies; immune reactions differ.33:54 Common cleaning methods can't completely remove mold.39:37 Mycotoxins influence intestinal permeability and healing.42:48 Mycotoxins trigger immune reactions, affecting mold-sensitive individuals.45:11 Gut dysbiosis is influenced by mycotoxins and immunity.48:42 Mold sensitization can cause lifelong health issues.52:02 Mold spores cause symptoms; mycotoxins affect everyone.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

    Episode 46: Navigating Chronic Infections

    Play Episode Listen Later Nov 12, 2024 80:31


    In this episode, Dr. Kharrazian discusses chronic infections and antibiotic resistance. Topics include hidden pathogen reservoirs, the role of biofilms in persistent illnesses, and why future generations may struggle with basic bacterial treatment. Hear about innovative strategies like probiotics, fecal transplants, and natural disruptors combating resistant strains. Discover how maintaining immune health is key to battling evolving bacteria and learn practical tips to protect yourself. Learn more at drknews.comFor patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 Bacteria classified by Gram stain, cause illness.07:25 Intestinal permeability leads to severe systemic inflammation.10:58 Systemic inflammation, endotoxemia: barrier breakdown, severe illness.20:21 Mycobacterium tuberculosis can reactivate when immunocompromised.26:06 Biofilms cause 80% of chronic bacterial infections.28:25 Biofilms influence IBS and ulcerative colitis severity.33:04 Biofilms cause persistent infections and antibiotic resistance.38:51 Combine medication and natural medicine for bacterial biofilms.45:30 Genetic predisposition causes recurrent E. coli infections.50:48 Poor hygiene impacts multiple body systems significantly.55:28 Bacteria developed resistance, antibiotics became ineffective.01:05:44 Probiotics with antibiotics reduce post-surgery complications.01:11:30 Antibiotics disrupt crucial short chain fatty acid levels.01:13:13 Use antibiotics, probiotics, and short-chain fatty acids.01:18:06 Candida aids immunity but causes problems if overpopulated.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

    Episode 45: Understanding Chronic Viral Infections

    Play Episode Listen Later Oct 21, 2024 67:35


    In this episode Dr. Kharrazian explores the world of chronic infections, such as Epstein-Barr Virus (EBV), Hepatitis C, Covid, and Human Cytomegalovirus (CMV), and their impact on our immune system. He explores how some pathogens hide within our bodies and reemerge when our immunity is compromised.He discusses the latest research linking these infections to autoimmune diseases and even cancer, and emphasizes the importance of enhancing our immune defenses rather than just relying on antiviral treatments. He covers a wide range of topics from the basics of virology, the dynamics of long COVID, and the sobering realities of Hepatitis C and Human Papillomavirus (HPV), to the ripple effects of viral infections on our overall health.Learn more at drknews.comFor patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 MHC proteins activate cells to fight infection.06:16 Long COVID factors: comorbidities, age, severity, inflammation, genetics13:50 Viral infection can trigger chronic inflammatory conditions.17:27 Long COVID linked to persistent antinuclear antibodies.22:53 Autoantibodies may form due to SARS-CoV-2 infection.27:28 Hepatitis B virus vaccine increases MS risk.33:58 Alphaviruses include herpes, 53% exhibit antibodies.39:30 Cytomegalovirus linked to autoimmune diseases, immune manipulation.45:39 Chronic Epstein Barr causes inflammation, cancer risk.52:02 Hepatitis C symptoms: diverse and system-wide impacts.57:33 High treatment costs spark global protests, denials.01:00:33 PCR measures viral load; biomarkers assess liver damage.01:06:08 Identify underlying health issues causing recurring infections.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

    Episode 44: Chronic Infections and the Immune System

    Play Episode Listen Later May 19, 2024 62:50


    This episode explores the world of the immune system's response to pathogens and chronic infections. Dr. Kharrazian discusses the intricate mechanisms pathogens use to evade the immune system, leading to chronic infections and reactivations. He speaks on the impact of immune compromise, genetic factors, and other environmental influences on the severity of infections and autoimmune diseases. He also discusses the pivotal role of protein intake, the formation of antibodies, and the potential link between pathogen-induced inflammation and neurodegenerative diseases.Learn more at drknews.comFor patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 Different pathogens have unique effects on health.06:30 Local infection can trigger widespread systemic inflammation.10:32 Chronic infections can reactivate and cause autoimmunity.18:51 Pathogens can lead to Alzheimer's disease development.24:38 Inflam aging causes inflammation and body pain.27:47 Blood contains complement systems, T and B cells, and innate adaptive immunity. Persistent pathogens hide in tissues, evade immune barriers. Chronic infections indicate immune system issues.33:02 Complement proteins indicate pathogenic load in blood.40:40 Importance of proteins in immune system activation.46:00 Genetics impacts response to viral infections.49:28 Weakened immunity can cause severe cytokine storms.55:02 Tick and pathogen invasion into tissues explained.58:53 Micronutrient deficiencies can impact immune compromise significantly.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

    Episode 43: Hormonal Imbalance Recap/Overview

    Play Episode Listen Later Apr 30, 2024 24:09


    In this episode, Dr. Datis Kharrazian discusses hormone disorders and their impact on puberty, perimenopause, menopause, and andropause. He discusses the onset of hormone-related issues, such as puberty and perimenopausal transition, and provides evidence-based strategies for addressing menstrual irregularities, hormone imbalances, adrenal function, and more. Dr. Kharrazian also delves into the effects of hormone replacement therapy (HRT), the role of essential fatty acids and seed oils, and the impacts of stress on hormone levels. Additionally, he answers questions on hormone therapy, hormone depletion, and the evaluation of pituitary tumors. Listeners will gain insights into managing hormone-related health conditions and understanding the complexities of the endocrine system.Learn more at drknews.comFor patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 Addressing imbalances, electrolyte depletion, and functional medicine.04:42 Underweight PCOS patients need specific health care.07:17 Chart discussed general symptoms, diagnostic steps, treatment.10:32 Analyze protein and fat intake for health.15:30 Weight loss can release stored toxins and hormones.18:29 Steroids and sleep, light, sound sensitivity strategies.20:14 Perimenopausal insomnia and low testosterone concerns addressed.23:31 Podcast content not a substitute for medical advice.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

    Episode 42: Hormone Therapy Strategies

    Play Episode Listen Later Mar 11, 2024 83:10


    In this episode, Dr. Kharrazian provides insights on growth hormone deficiency, testosterone replacement therapy, strategies for PCOS and infertility, and much more. From discussing the use of growth hormone stimulating peptides to addressing heavy menstrual bleeding and gallbladder issues, this episode offers evidence-based approaches to optimizing endocrine function. Learn more at drknews.comFor patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 Gradual use of HRT therapy based on age.08:27 Customized hormone therapy starts with low doses.13:03 Testosterone therapy aids weight loss in men.20:15 Testosterone replacement therapy may benefit men with diabetes.23:10 Testosterone replacement therapy in men is safe.30:20 Men with low testosterone treated with injections.35:05 Managing testosterone levels in men, potential issues.38:09 Dietary and lifestyle strategies impact hormones clinically.48:13 Music therapy, blood sugar, ketogenic diet, sleep issues.52:33 Nutraceuticals impact insulin resistance; fasting benefits.56:09 Women in menopause may experience gallbladder issues.01:03:26 Nutraceutical protocols, insulin signaling, PCOS treatment options.01:10:20 Evaluate hypoglycemia, insulin resistance, and dietary history.01:16:18 Decide on hormone therapy based on risks.01:17:43 Understanding aging and its impact on health.01:22:32 Podcast content not a substitute for medical advice.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

    Episode 41: Understanding Hormone Disorders

    Play Episode Listen Later Mar 5, 2024 89:48


    In this episode we dive into the intricate web of hormone imbalances, menstrual disorders, and andropause. We explore the impact of estrogen and progesterone imbalances on the menstrual cycle, as well as the role of prostaglandin imbalances in conditions like dysmenorrhea and PMS. We also uncover the complexities of andropause in males and address the various symptoms and treatment options available.Learn more at drknews.comFor patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com00:00 Female and male hormone transition patterns summarized.08:51 BMI impacts endocrine system, genetic factors matter.12:40 Excessive estrogen production causes gynecomastia in men.18:51 Prostaglandins influence menstrual pain and discomfort.26:21 Causes of heavy or light menstrual bleeding.32:24 High DHE and testosterone levels suggest PCOS.33:24 PCOS symptoms can normalize with metabolic control.38:45 PCOS pathophysiology, treatment, and clinical manifestations.45:19 Adrenal glands help manage perimenopausal symptoms.49:33 Hormonal changes in perimenopause cause inflammatory response.59:03 Inflammation and hormones affect women's health.01:03:18 Menopause can worsen underlying health conditions.01:06:44 Adulthood: decline in male function and symptoms.01:13:49 LH levels range indicates potential hormone balance.01:16:27 Free testosterone is crucial, especially as we age.01:25:04 Normal range testosterone, relative hypogonad men, DHT.01:27:26 Male and female hormone disorders patterns explained.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

    Episode 40: Hormone Balancing through Gut Health

    Play Episode Listen Later Feb 19, 2024 59:42


    In this episode, Dr. Kharrazian delves into the world of hormone imbalances, microbiome diversity, and the impact of polyphenols and phytoestrogens. He discusses evidence-based strategies for autoimmune disease, brain health issues, and chronic health conditions, and sheds light on the pivotal role of gut health in estrogen metabolism. He also addresses nutraceutical support for insulin resistance and regulating testosterone. For patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 Transitioning off HRT may benefit from modulators.06:05 Flavonoids affect estrogen receptor, 4 key foods.10:05 Healthy microbiome diversity enhances effectiveness of soy products.11:16 Carbs impact conversion of phytoestrogens efficiently.16:29 Gut health crucial for managing estrogen disorders.18:57 Diet, lifestyle, supplements affect microbiome diversity.20:53 Liver pathways detoxifying hormones, potential competition. Nutrients aid hepatic inflammation support.26:51 Essential fatty acids are critical for health.30:29 Prostate glands cause pelvic issues, need support.34:19 Men's testosterone, estrogen testing, insulin resistance, obesity, blood sugar imbalances, hypoglycemia, insulin resistance, dietary guidelines.36:02 Optimize diet to prevent blood sugar crashes.39:41 Review found herbal medicines improve PCOS symptoms.42:41 Aggressive protocol for PCOS using nutraceuticals.47:19 Nutraceuticals may protect serotonin cells, boost testosterone.50:44 Botanicals boost testosterone levels but may vary.53:42 Glial cells switch to pro-inflammatory state. Hormone changes amplify neuroinflammation.56:35 Peptides stimulate hormones, potential for endocrine treatment.58:37 Dr. Kharrazian's podcast and blog information.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

    Episode 39: Hormone Imbalance & Obesity

    Play Episode Listen Later Jan 31, 2024 89:43


    In this episode, Dr. Kharrazian provides insight into the impact of obesity on male and female hormone imbalances, infertility, and the body's endocrine system. From the role of adipose tissue to the effects of hormone replacement therapy, this episode explores the complexities of hormone balance and offers evidence-based strategies for managing these crucial aspects of health. Dr. Kharrazian discusses blood glucose management, gut health, and the impact of hormone deficiencies on mitochondrial function and other aspects of physiology.For patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/Learn more at drknews.comTimestamps:00:00 Hormones impact mitochondria, affecting cellular function.09:31 Mitochondrial health affects recovery and signaling pathways.12:00 Hormone replacement may fix mitochondrial dysfunction. Stress affects mitochondria.16:22 Certain genetic factors can increase health risks.25:26 Aromatization causes body fat increase, vicious cycle.31:00 Estrogen drop in women leads to fat tissue.32:52 Steroid use can disrupt endocrine system balance.42:35 Healthy adrenal function is crucial in perimenopause.48:03 Adrenal gland imbalances and stress responses summarized.53:04 Insulin resistance causes blood sugar roller coaster.57:10 Symptom patterns indicating early stages of insulin resistance.01:02:30 Gut bacteria convert chemicals and hormones.01:08:19 Hormone deficiency causes leaky gut, affecting health.01:12:26 Inflammatory diets cause low testosterone levels.01:20:18 Hormones critical for health and disease prevention.01:23:28 Hormone imbalances affect brain recovery and health.01:28:20 For more info visit drknews.com/podcast.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

    Hormone Imbalance and Environmental Toxins

    Play Episode Listen Later Jan 17, 2024 87:14


    In today's episode, we dive into the impact of hormone imbalance on overall health. From the critical role of adequate sleep in hormone regulation to the potential effects of environmental chemicals on endocrine function, Dr. Kharrazian shares valuable insights and evidence-based strategies for managing hormone imbalances.For patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/Learn more at drknews.com00:00 Toxic chemicals in everyday products, impacts on health.09:13 Endocrine disrupting chemicals impact female reproductive function.12:57 Endocrine disrupting chemicals impact PCOS in females.18:47 Endocrine disrupting chemicals impact serious health conditions.22:17 Inflammation impacts male testosterone and female infertility.32:18 Aquifers impact water supply with hormones, pharmaceuticals.34:54 Use multiple layers of water filtering systems.43:10 Air pollution impacts cortisol and microbiome health.48:26 Intense exercise is important for hormonal balance.52:57 Low or high body mass affects hormones.58:06 Injections are crucial for male obesity issues.01:03:36 Muscle mass affects health risks in obesity.01:08:32 Suppressed FSH, low TSH, hormone-related issues.01:12:27 Hormones, sleep, and strategies for better rest.01:19:50 Minimum needed protein is 1g/lb body weight.01:24:18 Blood sugar: Hypoglycemia vs insulin resistance management.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

    Personalized Strategies for Balancing Hormones

    Play Episode Listen Later Jan 2, 2024 83:13


    In this episode, we take a deep dive into the intricate world of hormone imbalances and hormone replacement therapy. Dr. Kharrazian discusses the latest research findings, revealing a clear linear dose-response relationship between oral contraceptive use and the risk of hypertension, as well as the links between hormone replacement therapy and various health concerns. We explore the complexities of hormone disorders and the need for a personalized approach to treatment, discussing the impact of hormones on clinical function, the liver, and the gut microbiome. Join us as we uncover the vital connection between hormones and overall health, as well as the challenges individuals face in receiving appropriate evaluation and treatment for hormone-related issues in the current healthcare system.Learn more at drknews.com00:00 Hormone disorders treated with diverse approaches.08:13 Hormone replacement therapies and over-the-counter options.14:10 Different types of hormonal contraceptives can cause weight gain and mood disorders.18:50 Glial cells produce main hormone for synaptic activity.25:45 Hormone replacement therapy not recommended for everyone.30:43 Testosterone therapy shows health benefits with low risk.37:49 Variety of lifestyle strategies for hormone balance.39:54 Viral infection may require immediate symptom management.48:43 Stimulating dysfunctional gland, hormones, pituitary issues, hormones.53:18 Protein pathways impact hormone levels causing symptoms.58:19 Androgel may not effectively metabolize into hormones.01:02:16 Microbiome dysbiosis consequences, particularly linked to hormones.01:08:23 Estradiol strongest, estrone not as strong.01:11:19 Urinary labs may not accurately test hormones.01:16:20 Maintain resiliency for hormone levels, health longevity.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

    How chronic systemic inflammation impacts the body and brain

    Play Episode Listen Later Oct 31, 2022 62:53


    In this talk, Dr. Kharrazian reviews the many pathways through which inflammation impacts the body. In a nutshell, inflammation is like throwing fuel onto the fire. Wherever you already have issues with pain or inflammation, an inflammatory diet and other triggers will simply worsen those conditions. Aging is another consideration — as we age we naturally become more prone to inflammation due to the gradual decline of the body's antioxidant systems. You will learn about these mechanisms, how to find triggers of inflammation, and anti-inflammatory and antioxidant strategies to mitigate the damage. Find out more on drknews.com.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

    Is it really SIBO?

    Play Episode Listen Later Aug 24, 2022 62:13


    The concept of small intestinal bacterial overgrowth is one that is becoming very popular but also widely misunderstood and confusing. Compared to the large intestine, there are very few bacterial species in the small intestine. When SIBO happens, the bacteria in the large intestine translocate to the small intestine causing fermentation, bloating, and excessive distension. Foods that commonly trigger SIBO symptoms include fibrous foods, sugar, sweeteners, prebiotics, and fermented foods.However, not all bloating and distension is SIBO. This is where confusion comes from. In this episode, I discuss how to tell it really is SIBO, SIBO tests, what causes it, and what to do about it.Find out more on drknews.com.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    Brain problems cause gut problems

    Play Episode Listen Later Aug 17, 2022 63:04


    Chronic gut health problems some people face can stem from brain-related dysfunction. Key groups of brain-related problems can cause gut problems: neurodegeneration, traumatic brain injury, neurological autoimmunity, and neurodevelopment disorders.In this episode, I discuss these key categories of brain-related problems and how they affect the gut through the vagus nerve as one of its functions is activating the gastrointestinal tract. Find out more on our website at Drknews.com.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    Glutathione: Your Most Important Defense

    Play Episode Listen Later Apr 22, 2022 62:11


    Glutathione is the body's master antioxidant, meaning it helps protect your cells from pathogens such as viruses. It also lowers the risk of developing food and chemical sensitivities, and is a powerful ally in managing autoimmunity and preventing tissue destruction.Unfortunately, environmental toxins, chronic stress, unhealthy diets, inflammation, medications, alcohol, aging, and many other factors continually deplete glutathione. Making sure your glutathione status is strong and reducing glutathione depletion can play a profound role in immune resilience to viruses and in managing autoimmune disease, inflammation, chemical sensitivities, food sensitivities, and other chronic health issues.In this podcast, Dr Kharrazian discusses what glutathione really is, and the supplements and precursors that come in many different forms. How do you know which one to take? How much should you take? How can you tell it's working?Find out more on our website at Drknews.comSupport this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    What thyroid lab tests really tell you

    Play Episode Listen Later Apr 15, 2022 21:56


    A complete thyroid panel can tell you about thyroid function, feedback loops, and how thyroid hormones are converting. The main thyroid markers are TSH, the pituitary hormone-stimulating gland, and T4 and T3, which are produced by the thyroid gland. Thyroid hormones are bound to proteins called thyroid hormone-binding globulins. Those are total T4 and total T3. T4 is converted to T3, which also makes reverse T3. At some point, thyroid-binding globulin levels release the T3 and T4, which then become free T3 and free T4. You can have defects all along these pathways, which I discuss in this podcast.To learn more, visit the site or the online Hashimoto's: Solving the Puzzle course page.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    Hypothyroidism and gallbladder function

    Play Episode Listen Later Apr 1, 2022 17:02


    If you have hypothyroidism, the first question you have to ask yourself is how long did it take to finally get diagnosed? Most people do not receive a diagnosis immediately after symptoms appear. What happens to most people instead is they struggle with symptoms for months or years: Hair loss, constipation, cold hands and feet, fatigue – symptoms get worse and worse and they keep developing new ones. Yet their doctor says their lab tests are normal until their thyroid function is bad enough to receive a diagnosis or they find a knowledgeable doctor. By then their body has been deprived of thyroid hormone for quite some time. One problem that can lead to is gallbladder sludge and gallstones. Gallbladder congestion in turns leads to poor absorption of fat-soluble vitamins such as vitamin D, which cascades into other health problems.This is one reason gallbladder issues are so common among hypothyroid patients.To learn more, visit the site or the online Hashimoto's: Solving the Puzzle course page.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    Common autoimmune diseases among thyroid patients

    Play Episode Listen Later Mar 30, 2022 15:50


    If you have hypothyroidism, there is a greater than 90% chance that Hashimoto's, an autoimmune disease, is the cause of your hypothyroidism. If you have one autoimmune disease, then you probably have other autoimmune diseases.Researchers once believed that autoimmunity was an isolated dysfunction of the gland from an autoimmune response that had no other systemic effects.Current research shows autoimmunity stems from immune dysregulation and loss of immune tolerance – meaning the immune system loses tolerance to foods, chemicals, and its own body tissue.This means that any tissue in the body is vulnerable to autoimmunity, and that the mechanisms that set into motion one autoimmune disease can lead to another.The goal is to regulate immune function and drive autoimmune expression into remission, which will lower your risk of developing future autoimmune diseases.You do this by identifying your triggers and following strategies that dampen inflammation and boost immune *regulation.* How you do this makes up the bulk of my content on my site (drknews.com) and in my books (on amazon).To learn more, visit the site or the online Hashimoto's: Solving the Puzzle course page.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    What thyroid antibody levels tell you about Hashimoto's

    Play Episode Listen Later Mar 17, 2022 11:10


    The two main antibodies to screen for Hashimoto's are thyroid peroxidase (TPO) antibodies and thyroglobulin (Tg) antibodies. It's important to check both because either one can be elevated, although TPO is more commonly elevated. An important thing to understand about thyroid antibodies, which are used to screen for autoimmune Hashimoto's hypothyroidism, is that the antibody itself isn't directly related to the severity of the disease. The T cell immune response, which attacks tissue tagged by antibodies, also plays a role. To learn more, visit the site or the online Hashimoto's: Solving the Puzzle course page.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    Why is it so hard to get a hypothyroidism diagnosis

    Play Episode Listen Later Mar 10, 2022 18:34


    Why is it so difficult to get diagnosed with hypothyroidism and Hashimoto's in the current healthcare system? As a healthcare practitioner, it's pretty rare when a patient says, "Yeah, I had symptoms and right away they diagnosed me with hypothyroidism.” Several reasons go into why it's hard to get a hypothyroidism diagnosis:• The disease comes on slowly so it can go misdiagnosed for years.• Doctors do not screen for thyroid antibodies that would catch early Hashimoto's because it's not covered by insurance or considered standard of care.• Conventional lab ranges are too wide.• TSH can fluctuate up and down and may be normal at the time of the test.• HMO doctors are assessed based on how much each of their patients cost and avoid tests they feel are unnecessary.To learn more, visit the site or the online Hashimoto's: Solving the Puzzle course page.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    Which thyroid medication is the best?

    Play Episode Listen Later Feb 25, 2022 17:28


    In this episode Dr. Kharrazian discusses the commonly asked question, which thyroid hormone replacement works best? The important thing to understand is there is not one optimal thyroid replacement. Issues exist with all types of replacement depending on the person and their unique situation and needs. Each person must figure out what their challenges and needs are and which thyroid hormone is most appropriate for them.To learn more, visit the site or the online Hashimoto's: Solving the Puzzle course page.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    How hypothyroidism affects blood sugar stability

    Play Episode Listen Later Feb 16, 2022 11:25


    Do you feel sleepy after you eat? Or do you feel energized after eating? Both responses indicate blood sugar instability. Chronically high blood sugar, low blood sugar, or swings between the two cause Hashimoto's flare ups and make the condition difficult to manage. At the same time, if you're in a low thyroid state from undiagnosed or poorly managed Hashimoto's, you're also susceptible to poor blood sugar handling. Low thyroid states both prevent uptake of glucose and promote insulin resistance. Subscribe to be notified of the free Hashimoto's webinar at drknews.com.To learn more, visit the site or the online Hashimoto's: Solving the Puzzle course page.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    Chelation therapy risks

    Play Episode Listen Later Dec 26, 2021 62:55


    Today's world is very toxic, and we all carry toxic chemicals and heavy metals in our bodies. Chelation is a popular therapy to lower heavy metal levels, however it's important to be aware of the risks—chelation can significantly worsen health in vulnerable people. Factors to consider include your antioxidant status, blood-brain barrier permeability, immune tolerance, gut health, autoimmune status, microbiome, and more. In this talk, Dr. Kharrazian covers heavy metal and chemical toxicity, risk factors to consider before chelation, forms of heavy metal testing, and daily strategies to lower the burden of toxins on your body.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    Endotoxemia: A hidden landmine for multiple health disorders

    Play Episode Listen Later Dec 15, 2021 62:03


    Endotoxemia happens when toxic byproducts from harmful gut bacteria escape through a leaky gut wall into the bloodstream. Here, they trigger significant inflammation throughout the body. Endotoxemia is linked with major depressive disorder, autoimmunity, joint disease, skin problems, poor immune resilience, difficulty recovering, aging poorly, and more. In fact, one thing people who live to 100 have in common is low levels of endotoxemia. Research also shows people with endotoxemia have a lower chance of surviving a critical illness or sepsis. In this talk, Dr. Kharrazian talks about the factors that cause endotoxemia, why it is considered the most severe form of leaky gut, and strategies for recovery. A Q&A with viewers follow. (From his Facebook Live 12-17-2020). To learn more about improving gut health, visit the online course Gut Health: Solving the Puzzle.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    How gluten impacts Hashimoto's & hypothyroidism

    Play Episode Listen Later Dec 8, 2021 27:57


    Contrary to popular belief, gluten intolerance is not a fad. Rates of gluten intolerance have risen dramatically due to many factors of industrialization. Unsurprisingly, significant links exist between gluten and autoimmunity, particularly Hashimoto's hypothyroidism. People with Hashimoto's low thyroid are more genetically prone to gluten sensitivity and celiac disease. Standard gluten sensitivity testing misses about 20% of positive cases because they only test for alpha gliadin. In truth, people can react to multiple compounds in wheat, which should be included in immune reactivity testing. Testing should also screen for the transglutaminase antibodies typically seen in celiac disease, a more destructive form of gluten sensitivity. Learn more in this podcast about how to correctly identify a gluten sensitivity and follow a gluten-free diet to better manage your Hashimoto's or other autoimmune disease.To learn more, visit the site or the online Hashimoto's: Solving the Puzzle course page.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    Hashimoto's and hypothyroidism Q&A -- Part 3

    Play Episode Listen Later Dec 1, 2021 47:52


    In this video, Dr. Kharrazian answers questions from members of the course Hashimoto's: Solving the Puzzle (drknews.com). Topics include:The role of thyroid binding globulin and the potential effect of birth control pills and hormone replacement.Stubbornly high TPO antibodies.The role of low dose naltrexone (LDN).What does it mean when TSH is low?What causes the swings between hyperthyroid and hypothyroid symptoms?Can hypothyroidism cause chronic sinus infections?The link between hypothyroidism and ferritin levels.Why are all my glands low functioning?What is myo-inositol and how can it help?Should I be worried about low serum iodine levels?Can I get off my thyroid meds or reduce the dosage?Do I need a thyroid ultrasound?What if I have symptoms of Hashimoto's but antibody tests are repeatedly negative?How do we find a competent healthcare professional to work with?Should I use bentonite clay?I developed Hashimoto's after having my ovaries and uterus removed.How do I reduce my reactions to chemicals?Does low vitamin D mean I have an infection?To learn more, visit the site or the online Hashimoto's: Solving the Puzzle course page.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    Hashimoto's and hypothyroidism Q&A -- Part 2

    Play Episode Listen Later Nov 24, 2021 40:44


    In this video, Dr. Kharrazian answers questions from members of the course Hashimoto's: Solving the Puzzle (drknews.com). Topics covered include: The optimal TSH level, food sensitivities and Hashimoto's, low thyroid symptoms but no diagnosis, testing total immuoglobulins before Cyrex testing, antibody testing when on immunosuppressants, CIRS and the Shoemaker protocols, why TPO antibodies are high yet TSH is normal, why symptoms swing between hypo and hyperthyroid, non-Hashimoto's causes of hypothyroidism, negative antibodies yet positive biopsy, thyroid hormone "injections," Hashimoto's and high cholesterol, hair dye and bleach, healing nodules, and thoughts on iodine.To learn more, visit the site or the online Hashimoto's: Solving the Puzzle course page.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    Hashimoto's and hypothyroidism Q&A -- Part 1

    Play Episode Listen Later Nov 17, 2021 46:55


    In this video, Dr. Kharrazian answers questions from members of the course Hashimoto's: Solving the Puzzle (drknews.com). Topics covered include what your thyroid antibodies mean for your Hashimoto's symptoms, how to know if a particular lab is reliable, coffee enemas, the impact of adrenal exhaustion on Hashimoto's, when to take your thyroid meds before lab testing, thyroid--brain concerns, why you may still have thyroid symptoms despite taking thyroid meds, and concerns regarding Hashimoto's, covid, and the covid vaccine.To learn more, visit the site or the online Hashimoto's: Solving the Puzzle course page.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    The vagus nerve and gut health

    Play Episode Listen Later Nov 11, 2021 56:58


    In this video, Dr. Kharrazian explains how the vagus nerve affects digestion and other aspects of gut health, factors that can compromise vagus function, and the best ways to strengthen your vagus nerve . Not all vagal exercises are alike and you want to use the most effective ones. Dr. Kharrazian has worked with many patients over the years whose gut health was significantly compromised from poor vagal tone, particularly those impacted by brain injury.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    How hypothyroidism causes depression and anxiety

    Play Episode Listen Later Oct 27, 2021 18:36


    If you struggle with chronic depression, anxiety, or other mood disorders, you may suffer from undiagnosed hypothyroidism. A thyroid hormone deficiency can cause multiple brain-based symptoms. This is because thyroid hormones play an important role in the function of many areas of the brain, including neuron health, brain immune cells called neuroglia, and the blood-brain barrier. If you have a chronic mood disorder, consider asking your doctor to screen for hypothyroidism with a TSH test and for autoimmune Hashimoto's with a TPO and TGB antibody test in order to rule these conditions out. Learn more in this podcast episode or in my online course, Hashimoto's: Solving the Puzzle.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    The best (and worst) supplements for Hashimoto's hypothyroidism

    Play Episode Listen Later Oct 20, 2021 14:45


    Not all thyroid supplements are equally effective – in fact, some can actually make your hypothyroid symptoms worse. You might have come across the mistaken belief that hypothyroidism is caused by a nutritional deficiency of iodine, tyrosine, or thyroid glandulars. This is an outdated theory from the 1950s and ‘60s that unfortunately still persists today. In actuality, iodine and tyrosine are not the best options for those with Hashimoto's – and thyroid glandulars should never be used as a replacement for thyroid medication. However, some nutraceuticals can be very supportive of hypothyroidism and Hashimoto's. Learn more in this episode or check out my course, Hashimoto's: Solving the Puzzle. Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    The best diet for Hashimoto's hypothyroidism

    Play Episode Listen Later Oct 13, 2021 21:46


    It's an incredibly common question among hypothyroid patients: what's the best diet for hypothyroidism? While specific diet plans can certainly make a profound impact, for the best results you have to tailor your diet to your individual needs. Outdated myths persist when it comes to the best diets for hypothyroidism, and we should tackle some of those before moving ahead into the best diet options for you. Learn more in this podcast episode or in my course, Hashimoto's: Solving the Puzzle.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    Environmental chemicals and hypothyroidism

    Play Episode Listen Later Oct 6, 2021 18:04


    You might not realize just how many chemicals you encounter on a day-to-day basis. Each of us is routinely exposed to thousands of different chemicals – many of which can impact your thyroid health. Some of these chemicals are cleared out of the body through liver “biotransformation.” Commonly called detoxification, this is the process through which liver enzymes convert chemicals into water-soluble compounds that can be properly eliminated through sweat, urine, and feces.Chemicals that can be processed and eliminated in this way include pesticides, plastics, fire retardants, and many other chemicals in our food, water, and air.But there's a group of chemicals that cannot be cleared out of the body, including heavy metals like mercury, lead, and arsenic. Since they cannot be expelled, metals are stored in the fat and bone. Learn more in this episode or in my course, Hashimoto's: Solving the Puzzle. Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    How hypothyroidism affects gut health

    Play Episode Listen Later Sep 29, 2021 19:09


    If you've been diagnosed with hypothyroidism, you should know low thyroid function can impact your gut health. This is why it's important to properly manage the underlying mechanisms of your hypothyroidism. An intimate relationship exists between your gastrointestinal tract and your thyroid, with each affecting the other. The health of the stomach, gut microbiome, pancreas, liver, gallbladder, and large intestine are all interrelated with thyroid function. Additionally, the inflammation and autoimmune mechanisms associated with Hashimoto's cause thyroid receptor site resistance and low thyroid function. Learn more in this podcast episode.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    The #1 rule when working on gut health

    Play Episode Listen Later Sep 15, 2021 60:32


    If you're like 3/4 of Americans, you suffer from IBS, diarrhea, acid reflux, constipation, abdominal pain, leaky gut, SIBO, bloating and gas, and so on. In this podcast Dr. Kharrazian explains the number-one rule he follows when working with any gut health patient: Start at the top and work your way down. If you are trying to improve your microbiome but your gallbladder is congested, you likely won't be successful. If you have IBS symptoms but you're not addressing low stomach hydrochloric acid, or if you are constipated and your brain is dysfunctioning due to a head injury, neuroinflammation, or degeneration, again, your success will be limited. In this information-packed episode, Dr. Kharrazian goes over the broad strategies of addressing gut health disorders and takes questions from viewers.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    "Leaky brain" in brain fog, fatigue, and depression

    Play Episode Listen Later Sep 8, 2021 61:01


    You may have heard of leaky gut but did you know you can get leaky brain too? The most common symptoms are brain fog and slower mental speed, but an intestinal blood-brain barrier plays a role in numerous brain disorders. Learn more in this episode and from great viewer questions.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    Mold toxicity — a silent factor in chronic illness

    Play Episode Listen Later Sep 1, 2021 58:29


    Mold toxicity is a silent factor a lot of people don't consider when rooting out causes for chronic health issues. Because most of its signs and symptoms are invisible to everyone else, it often goes unsuspected until symptoms become disabling. Many factors can play a role in mold toxicity, from water damage in your home, school, or workplace, to indoor humidity levels, genetic susceptibility, and your unique immune function. In this podcast, Dr. Kharrazian explains how mold toxicity occurs, what to look out for, ways to test for and address it, and more. Followed by a Q&A with listeners.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    GI symptoms from low stomach acid and gallbladder sludge

    Play Episode Listen Later Aug 25, 2021 56:34


    Low stomach acid and gallbladders sludge are very common gut issues in Americans. Low stomach acid can lead to symptoms such as acid reflux, heartburn, indigestion, belching and bloating, and discomfort after eating meats and proteins. Gallbladder sludge can lead to belching and bloating, burping up fish oil capsules, and discomfort after eating fats. Both of these disorders lead to problems throughout the digestive tract and can raise your risk of chronic disease. Instead of always reaching for the antacids or other drugs, learn the various underlying causes of these issues and what to do about them in this video. The good news is they often are easily managed. Learn more at drknews.com. Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    Histamine and Mast Cell Activation Syndrome (MCAS)

    Play Episode Listen Later Aug 18, 2021 61:10


    In this episode, Dr. Kharrazian goes over the primary mechanisms of histamine intolerance and mast cell activation syndrome (MCAS). But first, make sure you even have these conditions as these diagnoses are being tossed around a little too casually these days. While the low-histamine diet may reduce symptoms, it does not necessarily address the underlying causes and it deprives you of cultured foods, which support microbiome diversity. Additionally, MCAS is a very serious condition, so make sure your self-diagnosis is valid or you may be addressing the wrong target.Dr. Kharrazian covers all these topics in a 20-minute talk and then answers questions from viewers. If you suspect you have histamine intolerance or MCAS, this video gives a great foundation from which to move forward.Synopsis:Symptoms of histamine intoleranceSkin urticariaNasal congestionAnaphylaxisWheezingChronic gastrointestinal issuesChronic migraine issues Key things to note with histamine reactionsDetermine if you actually have histamine intolerance by taking an antihistamine and looking for relief from symptoms.Multiple food sensitivities doesn't necessarily mean you have a mast cell/histamine response.Food sensitivities are delayed IgG response or an IgM responses.Histamine responses involve immediate IgE responses.An allergic reaction IgE reaction to foods and environmental chemicals activate mast cells, which release chemical mediators, including histamine. Mast cell activationHealthy response: Exposure to the antigen triggers mast cells.Occasional symptomatic response: Occasional reactions to triggers such as pollen or pet dander.Chronic histamine response: Chronic histamine issues with constant symptomsMast Cell Activation Syndrome (MCAS): Massive and chronic mast cell response. The body is producing excess mast cells with exaggerated activity, causing significant and severe symptoms Things to look at when you have a histamine responseGenetically low DAO enzymeMethylation issuesExposure to an allergen that develops IgE reactions, e.g mold, parasitic, Lyme infectionUnderlying triggersWhat is amplifying the immune responsesImmune toleranceOther chronic health issues (leaky gut, leaky lung, low vitamin D, etc.) Mast Cell Activation SyndromeMast cell activation stream is the most aggressive form of histamine reaction, has criteria for diagnosis, and may require pharmacological treatment. Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    Causes and solutions for chronic bloating

    Play Episode Listen Later Aug 11, 2021 62:23


    Chronic bloating and abdominal distention are common gut health complaints. In this podcast, Dr. Kharrazian covers the primary causes of bloating and how to start implementing solutions. Multiple things can cause bloating, with the underlying mechanisms depending on the individual. You must work north-to-south in the GI tract to identify where your issues lie. Brain-based mechanisms, chewing, stomach health, pancreatic and gallbladder function, microbiome health, motility, and SIBO are discussed in this podcast, followed by a Q&A with listeners. (This is a replay of a Facebook live from June 2020, you can also watch it on YouTube.)To learn more about how to identify and address common gut health issues, check out the online course Gut Health: Solving the Puzzle. Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    How hypothyroidism affects your appearance

    Play Episode Listen Later Aug 4, 2021 28:50


    Hypothyroidism, or low thyroid function, impacts your skin, hair, nails, joints, body inflammation, systemic inflammation—all of which affect your physical appearance. The most common cause of hypothyroidism is an autoimmune disease called Hashimoto's, a disorder that causes the immune system to attack and destroy the thyroid gland. It is an incurable condition but can typically be driven into remission through evidence-backed nutrition and lifestyle strategies.Hashimoto's creates a heightened state of inflammation. It can also lead to secondary autoimmune diseases that cause hair loss, joint pain, and skin conditions, further affecting appearance.For many people, thyroid hormone medication alone will not relieve symptoms—the underlying autoimmune condition must be managed as well in order to feel and function better, and address the factors affecting your appearance.Download Dr. Kharrazian's free guide, Hashimoto's, Hypothyroidism, and the Brain.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    How hypothyroidism affects the body and causes a variety of symptoms

    Play Episode Listen Later Jul 28, 2021 33:33


    What happens to your health when your thyroid hormones are low? In this episode, Dr. Kharrazian talks about the various conditions that can cause low thyroid hormones, including Hashimoto's disease, improper hormone conversion, and incorrect hormone replacement. He then goes through the impact of thyroid hormone deficiency on different systems in the body and how that can affect symptoms and health. Of particular concern is the impact of neglect or misdiagnosis of hypothyroidism on the brain and the cardiovascular system. Through this podcast episode, we hope to give you a better understanding of how your thyroid works and what to expect when facing hypothyroidism. Download Dr. Kharrazian's free guide, Hashimoto's and the Brain.Support this show at: http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian.See acast.com/privacy for privacy and opt-out information.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    Gluten and Chronic Health Conditions

    Play Episode Listen Later Jul 2, 2021 64:08


    Gluten is a much more complex topic than most people realize. First of all, most gluten sensitivity testing is extremely limited as it only tests alpha gliadin. The truth is, people can react to many different portions of wheat, including the lectins in wheat agglutinin, and various other gliadans besides alpha gliadin. Unless you screen for an immune reactivity to all of these compounds using ELISA testing, you may end up with a false negative result. Secondly, people can have varying reactions that can include cross reactivity between gluten and other foods or body tissue, autoimmune reactivity involving transglutaminase enzymes, and more depending on their type of gluten sensitivity. Wheat is not the same compound it was 50 years ago due to hybridization and heavy glyphosate use, which research suggests accounts for the increase in gluten sensitivity in the population. Also, it's important to note that 2/3 of reactions to gluten are expressed in the brain and nervous system, not in the GI tract. Learn more in this podcast and from the Q&A session following the talk.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    Understanding PANS and PANDAS

    Play Episode Listen Later Jul 2, 2021 65:19


    PANDAS and PANS are autoimmune brain disorders that affect children in the aftermath of a strep infection or other infections. Symptoms include sensory, emotional, or movement disorders. These conditions are often misunderstood, misdiagnosed, and inappropriately treated. In this talk, I explain what causes PANDAS and PANS, lab testing, management strategies, and expected challenges in working with children. I then answer listener questions.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    How Gluten Affects the Brain

    Play Episode Listen Later Jul 2, 2021 63:55


    Do you suffer from fatigue, brain fog, depression, cognitive issues, mood or psychiatric issues, or memory loss? A gluten sensitivity manifests neurologically in 2/3 of people — most people do not have gut symptoms in response to gluten. Researchers call gluten sensitivity a neurological disease.Yet gluten sensitivity is significantly under diagnosed due to incomplete testing. If you have brain fog, cognitive, mood, psychiatric, or fatigue issues, you need to listen to this podcast. Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    The Top 10 Triggers of Autoimmune Disease and Flare Ups

    Play Episode Listen Later Jul 2, 2021 62:38


    Many people think their autoimmune management depends on diet. While diet plays a key role, it does not go the full distance for everyone. The autoimmune journey involves finding your underlying mechanisms and triggers. They are different for everyone...and they are not always obvious. First, you have to know what the possible triggers are. Research has identified quite a few. Then you have to know how to find them, and what to do about them.In this podcast, I go over the top 10 most common triggers of autoimmunity and then answer questions from listeners.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

    10 Reasons Autoimmune Patients Don't Get Better

    Play Episode Listen Later Jul 1, 2021 59:16


    It takes the average autoimmune patient 10 years and visiting 20 doctors before receiving an autoimmune diagnosis. There is very little medical training on autoimmunity and the disease must be quite advanced before doctors can intervene. In the meantime, patients suffer not knowing what to do.As a result, you must take charge of your own health and education when it comes to autoimmunity. Ample research exists on strategies to manage autoimmunity and drive it into remission.I see my patients run into 10 common challenges when managing their autoimmunity. One thing you won't find on this list is a supplement deficiency. Instead, key dietary and lifestyle habits, and attitudes about your own health play the most important roles in managing autoimmunity for many people.In this podcast I outline the top 10 reasons why people with autoimmunity don't get better, and then I answer questions from listeners.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

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