Podcasts about Cytomegalovirus

Did you know that congenital cytomegalovirus (cCMV) is the most common congenital viral infection in newborns and a leading cause of non-genetic hearing loss? Despite its prevalence, awareness and screening for cCMV remain inconsistent across healthcare systems. In this episode, we dive into the critical importance of cCMV screening, early diagnosis, and intervention. Join our expert guests Dr. Ingrid Camelo and Dr. John Noel as they discuss: The impact of cCMV on neonatal and long-term health outcomes Best practices for screening and diagnostic methods The role of early intervention, including antiviral therapy How advocacy efforts are shaping the future of universal screening policies Tune in to stay informed on how pediatricians and healthcare providers can play a vital role in improving outcomes for infants affected by cCMV. Special thanks to Dr. James Grubbs for peer reviewing this episode. CME Credit (requires free sign up): Link Coming Soon! References:  American Academy of Pediatrics. A targeted approach for congenital cytomegalovirus. Available at: https://publications.aap.org/pediatrics/article/139/2/e20162128/60211/A-Targeted-Approach-for-Congenital-Cytomegalovirus. Accessed August 13, 2024. Chiopris G, Veronese P, Cusenza F, Procaccianti M, Perrone S, Daccò V, Colombo C, Esposito S. Congenital cytomegalovirus infection: update on diagnosis and treatment. Microorganisms. 2020 Oct 1;8(10):1516. doi: 10.3390/microorganisms8101516. PMID: 33019752; PMCID: PMC7599523. Gantt S. Newborn cytomegalovirus screening: is this the new standard? Curr Opin Otolaryngol Head Neck Surg. 2023 Dec 1;31(6):382-387. doi: 10.1097/MOO.0000000000000925. Epub 2023 Oct 11. PMID: 37820202. Minnesota Department of Health. Minnesota implements universal newborn screening for cytomegalovirus. Available at: https://www.health.state.mn.us/news/pressrel/2023/ccmv020823.html. Accessed August 13, 2024. National CMV Foundation. Advocacy: universal newborn CMV screening. Available at: https://www.nationalcmv.org/about-us/advocacy#:~:text=Minnesota%20was%20the%20first%20state%20to%20enact%20universal%20newborn%20CMV%20screening. Accessed August 13, 2024. New York State Department of Health. Newborn screening for cytomegalovirus. Available at: https://www.health.ny.gov/press/releases/2023/2023-09-29_newborn_screening.htm#:~:text=ALBANY%2C%20N.Y.,all%20babies%20for%20the%20virus. Accessed August 13, 2024. UpToDate. Congenital cytomegalovirus (CMV) infection: clinical features and diagnosis. Available at: https://www.uptodate.com/contents/congenital-cytomegalovirus-ccmv-infection-clinical-features-and-diagnosis?search=cmv%20screening&source=search_result&selectedTitle=1%7E28&usage_type=default&display_rank=1#H92269684. Accessed August 13, 2024. UpToDate. Congenital cytomegalovirus (CMV) infection: management and outcome. Available at: https://www.uptodate.com/contents/congenital-cytomegalovirus-ccmv-infection-management-and-outcome?search=congenital%20cmv&source=search_result&selectedTitle=2%7E66&usage_type=default&display_rank=2. Accessed August 13, 2024. UpToDate. Ganciclovir and valganciclovir: an overview. Available at: https://www.uptodate.com/contents/ganciclovir-and-valganciclovir-an-overview?search=ganciclovir&source=search_result&selectedTitle=2%7E80&usage_type=default&display_rank=1#H6. Accessed August 13, 2024. University of Texas Medical Branch. Neonatology manual: infectious diseases. Available at: https://www.utmb.edu/pedi_ed/NeonatologyManual/InfectiousDiseases/InfectiousDiseases3.html#:~:text=may%20be%20required.-,Cytomegalovirus,Clinical%20findings. Accessed August 13, 2024. National Center for Biotechnology Information. Cytomegalovirus (CMV) infection. Available at: https://www.ncbi.nlm.nih.gov/books/NBK541003/. Accessed August 13, 2024.                                                                                                             

In this podcast, George Lawson and Hermione Lyall discuss their paper 'Polymicrogyria in infants with symptomatic congenital cytomegalovirus at birth is associated with epilepsy: A retrospective, descriptive cohort study'.   The paper is available here: https://doi.org/10.1111/dmcn.16250   Follow DMCN on Podbean for more:  https://dmcn.podbean.com/ ___ Watch DMCN Podcasts on YouTube: https://bit.ly/2ONCYiC __ DMCN Journal: Developmental Medicine & Child Neurology (DMCN) has defined the field of paediatric neurology and childhood-onset neurodisability for over 60 years. DMCN disseminates the latest clinical research results globally to enhance the care and improve the lives of disabled children and their families.   DMCN Journal - https://onlinelibrary.wiley.com/journal/14698749 ___ Find us on Twitter! @mackeithpress - https://twitter.com/mackeithpress

In this episode, Dr. Jake breaks down the must-take supplements for chronic cytomegalovirus (CMV). As a naturopathic medical doctor, he shares natural and non-toxic treatment protocols to help manage CMV effectively. Whether you're dealing with a chronic recurrence or facing acute symptoms, Dr. Jake's got you on that with his expert insights. Discover how supplements like monolaurin, cat's claw, and vitamin D, among others, can support your body's fight against this persistent virus, reducing inflammation and boosting your immune system. Experience the empowering world of integrative health and learn how these natural remedies can be a vital part of managing health conditions like autoimmune diseases. Don't miss out on understanding the root cause of your symptoms and how to address them naturally. Subscribe to Dr. Jake's channel for more insights and take control of your health journey today. #Cytomegalovirus #NaturalHealing #IntegrativeHealth Use the Promo Code DrJake to get 15% off any supplements at Dr Jake's supplement store https://shop.integrativemedica.com Ready for the best mitochondrial support system? Try Dr Jake's special mushroom "coffee" called Terrabru at https://terrabru.com and get real energy that supports your body at the cellular level. Want to get help from Dr Jake or one of his doctors? Visit https://integrativemedica.com and book an appointment. You don't need to live in the SLC area and can schedule a virtual appointment from anywhere in the United States and even outside of the country.

Join us as we discuss cytomegalovirus infection in pregnancy. CMV is a common cause of hearing loss in newborns and can cause other congenital anomalies. It is a common infection that's easily transmitted. Learn about it and what you can do.

In this episode Dr. Kharrazian explores the world of chronic infections, such as Epstein-Barr Virus (EBV), Hepatitis C, Covid, and Human Cytomegalovirus (CMV), and their impact on our immune system. He explores how some pathogens hide within our bodies and reemerge when our immunity is compromised.He discusses the latest research linking these infections to autoimmune diseases and even cancer, and emphasizes the importance of enhancing our immune defenses rather than just relying on antiviral treatments. He covers a wide range of topics from the basics of virology, the dynamics of long COVID, and the sobering realities of Hepatitis C and Human Papillomavirus (HPV), to the ripple effects of viral infections on our overall health.Learn more at drknews.comFor patient-oriented courses, visit https://drknews.com/online-courses/For CE and CME practitioner courses, visit https://kharrazianinstitute.com/00:00 MHC proteins activate cells to fight infection.06:16 Long COVID factors: comorbidities, age, severity, inflammation, genetics13:50 Viral infection can trigger chronic inflammatory conditions.17:27 Long COVID linked to persistent antinuclear antibodies.22:53 Autoantibodies may form due to SARS-CoV-2 infection.27:28 Hepatitis B virus vaccine increases MS risk.33:58 Alphaviruses include herpes, 53% exhibit antibodies.39:30 Cytomegalovirus linked to autoimmune diseases, immune manipulation.45:39 Chronic Epstein Barr causes inflammation, cancer risk.52:02 Hepatitis C symptoms: diverse and system-wide impacts.57:33 High treatment costs spark global protests, denials.01:00:33 PCR measures viral load; biomarkers assess liver damage.01:06:08 Identify underlying health issues causing recurring infections.Support this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

Vincent travels to the Karolinska Institute in Stockholm to meet up with Niklas Björkström and Joakim Dillner to review their research on the endometrial immune system, and the plan to eliminate cervical cancer in Sweden. Host: Vincent Racaniello Guests: Niklas Björkström and Joakim Dillner Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server Endometrial immune system variation (Sci Immunol) Immune defense in the womb (News from Karolinska) HPV vaccination and screening for elimination (Nat Comm) Cervical cancer elimination strategies (Int J Cancer) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

On episode #64 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 9/14 – 9/25/24. Host: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Viral Outcomes of Intravenous Immunoglobulin treatment of immunocompromised patients with viral respiratory infections (Annals of Allergy, Asthma & Immunology) Comparative Emergence of Maribavir and Ganciclovir Resistance for Treatment of Cytomegalovirus Infection (JID) Antibody persistence and safety of a live-attenuated chikungunya virus vaccine up to 2 years after single-dose administration in adults in the USA (LANCET Infectious Disease) Bacterial Determinant of 30-Day Mortality of Pulmonary Legionellosis (OFID) Donor-derived bartonellosis in Solid Organ Transplant recipients (American Journal of Transplantation) An Opt-Out Emergency Department Screening Intervention Leads to Major Increases in Diagnosis of Syphilis (OFID) Fungal The Last of US Season 2 (YouTube) Fungal disease week (CDC) Bridging Echinocandin with Azole antifungal Therapy On Prevention Of Invasive Candidiasis Post Lung Transplantation (OFID) Early Introductions of Candida auris Detected by Wastewater Surveillance, Utah, USA, 2022–2023 (Emerging Infectious Diseases) Parasitic Toxoplasma gondii Infection of Alzheimer's Disease Mice Reduces Brain Amyloid Density Globally and Regionally (JID) Miscellaneous Effect of Social Distancing Caused by Heavy Snowfall on Seasonal Influenza Epidemic in a Local Region in Japan (Pediatric Infectious Disease Journal) Music is by Ronald Jenkees Information on this podcast should not be considered as medical advice.

In this episode, we review the high-yield topic of ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Gonorrhea⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the Infectious Disease section at ⁠Medbullets.com⁠ Follow ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets Linkedin: https://www.linkedin.com/company/medbullets

In this episode, we review the high-yield topic of ⁠⁠⁠⁠⁠⁠⁠⁠⁠Cytomegalovirus⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠from the Infectious Disease section at Medbullets.com Follow ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Medbullets⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets Linkedin: https://www.linkedin.com/company/medbullets

Clustered regularly interspaced short palindromic repeats (CRISPR-Cas12a), discovered a few years ago, is a method that detects even small levels of pathogens.Professor Kevin J Zwezdaryk and researchers at the Tulane University School of Medicine, USA, are working on a cost-effective, CRISPR-Cas12a-based pathogen detection tool aiming to upgrade patient care. Read more in Research Features Read the original research: doi.org/10.1016/j.bmt.2023.03.004

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Dane Johnson is the Founder/CEO of Crohn's Colitis Lifestyle and a Holistic Nutritionist specializing in reversing Crohn's Disease and Ulcerative Colitis. Dane's story ignited through a life-threatening case of Crohn's/Colitis which nearly took his life December 2014. Since committing his life to natural healing he has remained surgery and medication-free while eliminating IBD symptoms. To date, Dane and his passionate team of specialists and coaches have created 500+ success stories for reversing IBD symptoms using his signature S.H.I.E.L.D. Program. His international IBD consulting firm is one of the few organizations in the world that only treat IBD, and see roughly 100+ international IBD cases a week despite any unique needs! Dane and his team have successfully worked with of IBD clients despite surgery, age, medication, past experiences, diet preferences, extreme cases, world location or culture. His passion, unique experience, and niche in the field of IBD have empowered him to create unparalleled value for real, long-term symptom relief for those suffering from Inflammatory Bowel Disease. In this episode, Dane talks about gut health in general and specifically ulcerative colitis, Crohn's and IBD. He shares his story of being very sick and finding his way back to health, and now helping other people improve their gut health. Learn more about Dane here: http://crohnscolitislifestyle.com Instagram: @danejohnson1  @crohnscolitis_lifestyle Get Dane's SHIELD program here: https://cclpresentation.com/ibd-relief-special-podcast?source=InsideOutHealthPodcastTaraGarrison&el=InsideOutHealthPodcastTaraGarrison Get Dane's freebie journal here: https://drive.google.com/file/d/1bqLx3WsN3KuAMecfa0oNryDDAv_gyfx2/view?usp=sharing CHAPTERS: 0:00 Intro 3:05 Dane's journey of becoming a gut health expert 20:19 Prayer and the 'why' vs. fear driving you 26:30 Becoming self empowered 36:40 Cytomegalovirus, candida, mold and co-infections 42:10 Liver & bile 1:1:50 Nutrition advice    

Send us a Text Message.In this episode of "The Autoimmune RESET," VJ explores Stiff Person Syndrome (SPS), a rare and complex neurological disorder marked by severe muscle stiffness and spasms. With its autoimmune roots, SPS is often linked to other conditions like type 1 diabetes and vitiligo. VJ dives deep into the science behind SPS, focusing on its connection to pathogens such as Epstein-Barr Virus (EBV) and Cytomegalovirus (CMV). Learn how these infections might trigger or worsen SPS through mechanisms like molecular mimicry and bystander activation.We'll also discuss how SPS affects daily life, from the challenges of managing overstimulation and muscle control to its impact on high-profile cases like Celine Dion's career. Understand how SPS influences her ability to perform and the adjustments needed for managing symptoms while maintaining a demanding schedule.You will gain practical advice on living with SPS, including nutritional strategies, natural therapies, and stress management techniques that can help mitigate symptoms. Whether you're living with SPS, know someone who is, or are simply curious about this condition, this episode provides a thorough and compassionate overview of SPS, combining the latest research with real-world insights.Stiff Person Syndrome, SPS, autoimmune disorder, pathogens, infections, molecular mimicry, Celine Dion, Epstein-Barr Virus, Cytomegalovirus, natural therapies, overstimulation, health podcastYou can download your free copy of The Autoimmune RESET here.And you can access all of VJ's free resources here.If you would like to book a free initial consultation with VJ Hamilton, The Autoimmunity Nutritionist, to find out how nutritional therapy and functional medicine could improve your health, you can book an appointment here.Learn more about the functional medicine services at The Autoimmunity Nutritionist Clinic here.Thanks for listening! You can join The Autoimmune Forum on Facebook or find me on Instagram @theautoimmunitynutritionist.

Um parasita capaz de controlar mentes! Separe trinta minutinhos do seu dia e descubra, com a Mila Massuda, o ciclo e a influência comportamental do Toxoplasma gondii, o agente causador da toxoplasmose. Apresentação: Mila Massuda (@milamassuda) Roteiro: Mila Massuda (@milamassuda) e Emilio Garcia (@emilioblablalogia) Edição: Clayton Heringer (@tocalivros) e Juscelino Filho (@canalmusicalia) Produção: Prof. Vítor Soares (@profvitorsoares) @Matheus_Heredia e BláBláLogia (@blablalogia) Gravado e editado nos estúdios TocaCast REFERÊNCIAS: ATTIAS, M. et al. The life-cycle of Toxoplasma gondii reviewed using animations. Parasites & Vectors, v. 13, n. 1, 23 nov. 2020. BURGDORF, K. S. et al. Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders. Brain, Behavior, and Immunity, v. 79, p. 152–158, jul. 2019. COFFEY, M. J. et al. An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell. eLife, v. 4, 18 nov. 2015. INGRAM, W. M. et al. Mice infected with low-virulence strains of Toxoplasma gondii lose their innate aversion to cat urine, even after extensive parasite clearance. PloS one, v. 8, n. 9, p. e75246, 2013. JOHNSON, S. K. et al. Risky business: linking Toxoplasma gondii infection and entrepreneurship behaviours across individuals and countries. Proceedings of the Royal Society B: Biological Sciences, v. 285, n. 1883, p. 20180822, 25 jul. 2018. NGÔ, H. M. et al. Toxoplasma Modulates Signature Pathways of Human Epilepsy, Neurodegeneration & Cancer. Scientific Reports, v. 7, n. 1, 13 set. 2017. POIROTTE, C. et al. Morbid attraction to leopard urine in Toxoplasma-infected chimpanzees. Current Biology, v. 26, n. 3, p. R98–R99, fev. 2016. SUGDEN, K. et al. Is Toxoplasma Gondii Infection Related to Brain and Behavior Impairments in Humans? Evidence from a Population-Representative Birth Cohort. PLOS ONE, v. 11, n. 2, p. e0148435, 17 fev. 2016. UBOLDI, A. D. et al. Regulation of Starch Stores by a Ca2+-Dependent Protein Kinase Is Essential for Viable Cyst Development in Toxoplasma gondii. v. 18, n. 6, p. 670–681, 9 dez. 2015.

Lindsay struggled with infertility due to PCOS. She went through fertility treatment and got pregnant, but this ended in a miscarriage. She then got pregnant with her son Theo, but had to TFMR due to him having CMV (cytomegalovirus). Lindsay was able to get pregnant again and bring her rainbow baby home. --- Support this podcast: https://podcasters.spotify.com/pod/show/findinghopeafterloss/support

Only one in six pregnant women have ever heard of CMV, but if they contract it by kissing a young child on the mouth or sharing drinks they can put their unborn child at risk of serious disabilities. While very common in adults, the widely unknown congenital Cytomegalovirus or CMV, is one of the leading causes for birth defects in babies and can lead to them developing hearing loss, epilepsy and cerebral palsy. Obstetrician at the University of Sydney, Dr Antonia Shard, what this disease is, how new Mums can avoid catching it and why it remains widely unknown in the community.  You can find out more information on CMV prevention and treatment clicking on the link below: http://cerebralpalsy.org.au/cmvSee omnystudio.com/listener for privacy information.

Kennedy Concannon, PharmD discusses cytomegalovirus prophylaxis in solid organ transplantation. For more pharmacy content, follow Mayo Clinic Pharmacy Residency Programs @MayoPharmRes. You can also connect with the Mayo Clinic's School of Continuous Professional Development online at https://ce.mayo.edu/ or on Twitter @MayoMedEd. 

Christine Salvatore M.D. discusses what parents should know about the new universal screening for congenital cytomegalovirus (cCMV). She discusses what parents should know about CMV in newborns. While there is no CMV vaccine currently available to prevent congenital cytomegalovirus (CMV), she discusses the universal screening every baby for cCMV that's taking place in the country, including in New York State. She also shares precautions that adults can take to keep babies safe from the illness.To schedule with Dr. Christine M. Salvatore 

The dawn of each day is a precious time for Megan Nix--her youngest daughter was born at the start of a new day and her beloved mother later went home to God in the early morning hours.   Megan came to learn that not only was dawn the start of these soul-touching days, but also new seasons in her life. Seasons in which Megan would come to know the depth of grief and boundlessness of love.  Megan's daughter was was born into silence due to deafness caused by cytomegalovirus (CMV). Megan's heart was met with great sorrow as she processed the impact, learned the avoidable cause she was never told about and advocated for her daughter.  Megan discovered Aquinas' Remedies for Sorrow as she attended to her grief. Listen as Megan weaves personal stories of sorrow and healing with Aquinas' Remedies for Sorrow. Learn more about Megan and her book “Remedies for Sorrow: An Extraordinary Child, a Secret Kept from Pregnant Women, and a Mother's Pursuit of the Truth” at megannix.com.

Chronic Fatigue Syndrome is now officially known as Myalgic Encephalomyelitis (ME/CFS). The CDC believes this is a vastly under-diagnosed condition. In this episode, you'll learn:--Why Chronic Fatigue Syndrome was a diagnosis that did not get much respect. And why the name change was encouraged by government agencies in 2015.--How the Centers for Disease Control believes that 90-95% of cases are not being diagnosed or treated properly.--That even children can be affected by ME/CFS, though it is more common in women, minorities, and those between the ages of 33 and 50.--Why a person's "phase angle" (or electromagnetic charge around the cells) can indicate the condition.--How one-fourth of those with ME/CFS are bedridden and unable to function. And how the Social Security department wanted to create more awareness of this disease because it costs between $17 and $24 billion annually.--The symptoms of ME/CFS, including: severe fatigue for at least six months, cognitive impairment, muscle or joint pain, headaches, swelling of lymph nodes, sore throat, and complete exhaustion after any kind of mental or physical work.--The underlying viral infections that can cause ME/CFS, including: Epstein-Barr virus, Lyme Disease, Rickettsia, Retroviruses, Bornaviruses, Fungi and Mycoplasma, Flu viruses, Xenotropic murine leukemia virus-related virus (XMRV), and Cytomegalovirus.--Why The Structure-Function approach used by Holistic Integration is "really the only way of getting success" with this disease process. And why there is really no effective Disease Care approach to ME/CFS.--How Homeopathy stimulates the immune system to combat the underlying viruses that cause ME/CFS. And why those with ME/CFS "do not do well" with pharmaceuticals and antibiotics.--The effectiveness of supplementation, herbals, Chiropractic adjustments, Acupuncture, and therapeutic massage for ME/CFS patients. And the importance of blood analysis every three months for these patients.www.TheVoiceOfHealthRadio.com

On episode #43 of the Infectious Disease Puscast, Sara reviews the infectious disease literature for the weeks of 11/22 – 12/06/23. Host: Sara Dong Subscribe (free): Apple Podcasts, RSS, email Become a patron of Puscast! Links for this episode Treatment for first cytomegalovirus infection post-hematopoietic cell transplant (CID) Mortality among children aged

Dr. Ajit Limaye and Dr. Camille Kotton (@KottonNelson) join Dr. Erin McCreary (@ErinMcCreary) to discuss fascinating updates in the CMV space including new RCTs for prevention, vaccines, and more! Learn why a little "hair of the dog" might be a good thing, how great T cells are, and the trials we still need. References: CAPSIL study: Effect of Preemptive Therapy vs Antiviral Prophylaxis on Cytomegalovirus Disease in Seronegative Liver Transplant Recipients With Seropositive Donors: A Randomized Clinical Trial - PubMed (nih.gov) Extended CAPSIL data: Association of CMV DNAemia with Long-Term Mortality in a Randomized Trial of Preemptive Therapy (PET) and Antiviral Prophylaxis (AP) for Prevention of CMV Disease in High-Risk Donor Seropositive, Recipient Seronegative (D+R-) Liver Transplant Recipients - PubMed (nih.gov) Kidney transplant review: A Systematic Review and Meta-analysis of Optimized CMV Preemptive Therapy and Antiviral Prophylaxis for CMV Disease Prevention in CMV High-Risk (D+R-) Kidney Transplant Recipients - PubMed (nih.gov) Letermovir vs Valganciclovir for Prevention in Kidney Transplant: Letermovir vs Valganciclovir for Prophylaxis of Cytomegalovirus in High-Risk Kidney Transplant Recipients: A Randomized Clinical Trial - PubMed (nih.gov) Learn more about the Society of Infectious Diseases Pharmacists: https://sidp.org/About Twitter: @SIDPharm (https://twitter.com/SIDPharm) Instagram: @SIDPharm (https://www.instagram.com/sidpharm/) Facebook: https://www.facebook.com/sidprx LinkedIn: https://www.linkedin.com/company/sidp/ SIDP welcomes pharmacists and non-pharmacist members with an interest in infectious diseases, learn how to join here: https://sidp.org/Become-a-Member Listen to Breakpoints on iTunes, Overcast, Spotify, Listen Notes, Player FM, Pocket Casts, Stitcher, Google Play, TuneIn, Blubrry, RadioPublic, or by using our RSS feed: https://sidp.pinecast.co/ Check out our podcast host, Pinecast. Start your own podcast for free with no credit card required. If you decide to upgrade, use coupon code r-7e7a98 for 40% off for 4 months, and support Breakpoints.

In today's episode of Backpacker Radio presented by The Trek, we are joined by Brady Geilenfeldt. Brady, known on trail as Undies, thru-hiked the Colorado Trail this year. What makes Undies story especially interesting is that he is deaf. We learn all about Brady's inspiring story, the incredible technology that is cochlear implants, what challenges a deaf hiker has to overcome, Brady's highlights from the CT, some of the non-obvious benefits of being a deaf hiker, Brady's future trail ambitions, and much more. Brady is an inspiring young man and we think you'll really enjoy this chat. We wrap the show with things we're convinced people pretend to enjoy, a triple crown of things that are the new black, some new poop news, and we finally have the details for our Denver holiday hiker meetup, and you are invited. Vargo Outdoors: Use code “BACKPACKERRADIO” for 20% off at vargooutdoors.com. RTIC Outdoors: Shop at rticoutdoors.com. Darn Tough: Use code “DTLOVE-BACKPACKERRADIO” for 10% off plus free shipping at darntough.com. Katabatic Gear: Use code “BPR15” for 15% off at katabaticgear.com. [divider] Interview with Brady Geilenfeldt Brady's Instagram Time stamps & Questions 00:04:52 - Reminders: Join us at Improper City for the Hiker Meetup on December 1st! Apply to be a blogger or the Trek's editorial intern. Check out our merch and support us on Patreon! 00:08:32 - Introducing Brady 00:12:40 - Tell us about your experience with deafness 00:15:10 - How did your mom get CMV? 00:16:50 - Were your parents on high alert knowing your mom had CMV? 00:17:55 - Would you trade being deaf for anything? 00:18:57 - How well does a cochlear implant approximate human hearing? 00:21:04 - How do the implants work? 00:24:10 - Did you ever learn American Sign Language? 00:26:00 - Are your other senses enhanced to make up for the loss of hearing? 00:27:10 - Does it help you sleep at night while backpacking? 00:28:14 - Are the implants comfortable to wear? 00:29:40 - Can you customize the volume based on different environments? 00:31:20 - Is it a satisfying feeling to take them off? 00:32:28 - Do the implants make hiking more interesting? 00:35:32 - What's your hiking background and what made you decide to hike the CT? 00:37:18 - What was your longest backpacking trip prior to the Colorado Trail? 00:37:40 - What do you have to consider when planning for the CT? 00:40:28 - Is it disorienting to have only one implant in? 00:44:14 - Did you have any role models that inspired you beforehand? 00:46:20 - Do you have tips for making hiking more stimulating or being comfortable with yourself? 00:49:10 - Do you have to be concerned about the implants getting wet? 00:52:00 - Discussion about technological features or upgrades 00:53:40 - Do people ever use cochlear implants that aren't deaf? 00:55:05 - Does the implant need to be replaced? 00:57:17 - Did deafness or CMV cause you to be immunocompromised? 00:58:30 - Discussion about losing balance and other impacts of deafness 01:01:18 - How did you handle the weather on the Colorado Trail? 01:04:38 - Did you have to be more careful when navigating while hiking? 01:07:00 - Do you want to do future hikes with a trail family? 01:08:03 - Do you have any standout stories from the CT? 01:10:09 - What's the origin of your trail name? 01:14:54 - Would you do other things differently to prepare for a future hike? 01:17:50 - What ratio of rechargeable to disposable batteries did you use? 01:18:57 - How bad is it if you were to lose or break them? 01:21:22 - How did you handle health insurance? 01:23:55 - Have you had other people reach out since your hike? 01:25:00 - How does playing music interface with your deafness? 01:27:50 - Is there something to be done to make the outdoors more accessible for someone with implants? 01:30:41 - Are some insurance plans better than others? 01:32:33 - Is there an actionable step the listeners can take to improve the situation? 01:38:00 - Harvest General Store 01:40:15 - Brady's parting words Segments Trek Propaganda: Broken on the AT: Gear That Breaks At 2,000 miles (And The Gear That Doesn't) by Abby Evans QOTD: What are you convinced people are pretending to enjoy? Stupid Thing of the Week Triple Crown of things that are the new black Poop News Mail Bag 5 Star Review [divider] Check out our sound guy @paulyboyshallcross. Leave us a voicemail! Subscribe to this podcast on iTunes (and please leave us a review)!  Find us on Spotify, Stitcher, and Google Play. Support us on Patreon to get bonus content. Advertise on Backpacker Radio Follow The Trek, Chaunce, Badger, and Trail Correspondents on Instagram. Follow Backpacker Radio, The Trek and Chaunce on YouTube. Follow Backpacker Radio on Tik Tok.  Our theme song is Walking Slow by Animal Years. A super big thank you to our Chuck Norris Award winner(s) from Patreon: Alex & Misty with Navigators Crafting, Andrew, Austen McDaniel, Austin Ford, Brad & Blair (Thirteen Adventures), Brent Stenberg, Bryan Alsop, Christopher Marshburn, Coach from Marion Outdoors, Dayne, Derek Koch, Eric Casper, Greg McDaniel may he bring honor to his name, Ironhike endurance productions, Liz Seger, Matt Soukup, Mike Poisel, Patrick Cianciolo, Sawyer Products, SPAM, Timothy Hahn, and Tracy “Trigger” Fawns. A big thank you to our Cinnamon Connection Champions from Patreon: 12 Trees Farms, Dcnerdlet, Emily Galusha, Jeanne Latshaw, Jeff LaFranier, Joann Menzer, Keith Dobie Jr, Peter, and Ruth S. [divider] Transcript: In today's episode of Backpacker Radio, presented by The Trek, we are joined by Brady Geilenfeld. Brady, known on trail as Undies, through-hiked the Colorado Trail this year. What makes Undies' story especially interesting is that he's deaf. We learn all about Brady's inspiring story, the incredible technology that his cochlear implants, what challenges a deaf hiker has to overcome, Brady's highlights from the CT, some of the non-obvious benefits of being a deaf hiker, including a great night of sleep, future trail ambitions, and much more. Brady is an inspiring young man, and we think you'll really enjoy this chat. We wrap the show with things we're convinced people pretend to enjoy, a triple crown of things that are the new black, some new hoop news, and we finally have the details for our Denver Holiday Hiker Meetup, and you are invited. But first, I am thrilled to introduce our next sponsor, which is a brand that has been a part of my pack and through hikes, dating back to 2017. Vargo creates lightweight titanium backpacking gear that is simple, innovative, and functional. The Vargo Bot 700 was with me every step of the way during my through hike of the PCT and every backpacking trip since. The Vargo Bot is extremely lightweight, weighing less than 5 ounces, and transfers heat quickly and evenly, making it the perfect pot for your cookware setup. But this just scratches the surface for why the Bot kicks so much eff… butt. Because the Bot features a screw top lid, it's the ideal option for the cold soakers of this world. Dump your dehydrated meal and the appropriate amount of water into the Bot, screw the lid closed, insert time, and voila, dinner is ready. Also, I can't count all the times I've benefited from having an additional 700ml of emergency water storage when encountering an unexpected dry spell. In other words, this piece is incredibly versatile and may very well be the last pot you ever buy. The Bot comes in a variety of sizes, including the brand new Bot XL, which is designed to perfectly fit a full-size canister inside with extra room for a stove. I'm also a user and fan of Vargo's utensils, titanium long-handle spoon for the win, and their titanium stakes. You simply can't beat titanium's combination of strength and being lightweight, and no one does it better than Vargo. Discount time, backpacker radio listeners, head to vargooutdoors.com and use coupon code backpackerradio at checkout to score a 20% discount. Again, the code is backpackerradio, all one word, at vargooutdoors.com. This is a limited time deal, so do not wait. Whether it's a car camping trip, a bout of trail magic, or the summer road trip, a quality cooler and drinkware is essential. That's why we're thrilled to introduce our next sponsor, Artic Outdoors. Artic Outdoors makes products engineered for two things, performance and durability. And unlike other coolers on the market, Artic's high-quality coolers and tumblers won't cost you an arm and a leg. Artic's 52-quart ultralight hard cooler made the trip from backpacker radio's headquarters in Golden, Colorado, to Trail A's in Damascus, Virginia, keeping our spin drifts, root beers, and blue ribbons perfectly chilled. As the name would imply, the ultralight cooler is 30% lighter compared to other premium hard-sided coolers, which means you can be the group's beverage hero without developing a hernia in the process. And compromising on weight doesn't mean you're compromising on insulation. With up to three inches of post-self-roam insulation, your ice will remain as ice for days. For more portable adventures, Artic Outdoors soft pack coolers are the ticket. These are lightweight, durable, and ready to travel with you, keeping your drinks cold for up to 24 hours while avoiding the mess thanks to two inches of closed-cell foam and puncture and tear-resistant lining. Lastly, Artic's drinkware keeps your blue ribbons cold or your morning coffee hot for the long haul, utilizing double-wall vacuum insulation. The BPR team rocked Artic tumblers throughout the muggy afternoons of southern Appalachia, enjoying refreshingly cold beverages along the way. Head to ArticOutdoors.com to get your premium coolers and insulated drinkware at a fraction of the price of the competition today. Welcome to Backpacker Radio, presented by The Trek. Today is November 13th, World Kindness Day. Aww, that's nice. I am your co-host Zach Badger-Davis, sitting to my right is... Hi, I'm Juliana Chauncey, aka Chauncey... Reminders, yes. We have the deets, finally, for our Hiker Holiday Meetup Extravaganza Palooza Supreme. A-thon. Yes. This will take place, whatever I said previously, disregard that because I think a lot of the details have changed. You guys don't care about the reasons why. But this is going down on December 1st at Improper City in Denver, in Denver, not Golden, from 530 to 8 p.m. This will be co-hosted by Backpacker Radio slash The Trek and the CDTC, which means it'll be a fundraiser for them. We're going to have some sweet raffles, or as they say, door prizes. I had to look that up. Apparently, that's the vernacular for raffle prizes nowadays. Good hangs, solid vibes, memes. What else? Carnival barking. Carnival barking, yes. Sounds like there will be some of that happening. Give at least four drinks a chance and she will stand on a chair and yell at you. I haven't stood on a chair and yelled at Improper City yet, which is something that I'm excited to do. Yeah, let's see if they welcome us back after December 1st at 530 p.m. A couple other things quickly. One is if you're through hiking in 2024 and you want your journey featured on The Trek, we are currently accepting blogger applications. I did a link in the show notes. Lastly, this is the time of the year where we will likely be adding a new editorial intern to the team. This is a highly coveted position. We get lots of people reaching out for this, so if you're listening to this and you've got some serious editorial chops and you like long distance backpacking, head to the link in the show notes. Oh, also we are still selling our awesome vintage backpacker radio tees. We've gotten some nice compliments on them. Yes, we have. They look like Saved by the Bell goes outdoors. Yeah, or if you're slightly older, Miami Vice, if you're my age, both are sufficient. Yeah, I also think if you saw the Barbie movie, this would be like that in the form of a shirt and blue. There is pink hints. There's flavors of pink in there, but it's it's I could see it being worn as like a Ken costume. Yeah, I saw a couple people recommend or ask for us to turn these into sun hoodies, which I got to figure out. Where do we find a manufacturer? That's a good question, but maybe someday. OK, well, if you manufacture sun hoodies and you're listening to this slide in our DMS. Yes. Last thing is if you want to support the show and you want some additional backpacker radio content, head on over to our Patreon page, patreon.com slash backpacker radio, where we release a new episode the first Wednesday of every month. This current month's episode was a gift guide. We went through big ticket and small ticket items that you can either gift or be gifted in the holiday season, things that we've loved having as hikers and regular humans and as well as things that we wouldn't want or like, you know, some things to avoid if you want to give that thoughtful gift to a hiker, but also don't want to give them something that they're going to smile and say thank you for and then actually never use. Yes. To the non-backpacking gift recommendations, I tried my hardest to not make it too dad-centric and I think I failed. This will be a great one for anyone who wants to gift something to a hiker or who really likes being in the kitchen. Yes. Leave it at that. Or is training to be the all-time dad. Yeah. OK, we'll leave it at that. No more beating around the bush. Let's get right to today's interview with Brady Gielenfeldt. We'll figure out how badly I butchered that pretty soon. We are joined by today's guest, Brady Gielenfeldt, which I nailed the first time, I'm pretty sure. I'm sure the tape will say otherwise, who hiked the Colorado Trail this year in part to inspire people who are deaf or hard of hearing, that they are not limited by their abilities. Brady, thank you so much for joining us here on Backpacker Radio. Hey, it's great to be here. Yeah. Can we swing the mic a little bit closer your way? There we go. About that far from your mouth. How does that sound? Good. That sounds awesome. The closer the better. You can't be too close. Yeah. I would move yourself closer rather than close. Yeah. Typically, we do all this stuff before we hit record, but we're winging it here today. He brought us food. We got distracted and we brought him food. Yeah. It was a food exchange. Let's start there. Let's give a plug to this is your folks place, the Harvest General Store in Iowa, right? Yes, in Iowa. Yeah, they just do trade shows and stuff right now and they have a Facebook page. But I mean, really, yeah, they just go around doing those trade shows. They love it. Yeah. So we're about to bust open. There was a wide variety of goodies in this box. Chonce went with her top option, currently stabbing it open with the edge of her glasses. What do we have here, Chonce? This seemed the most on-brand for us, and this is freeze-dried gummy worms. I personally have been getting a lot of algorithm on socials showing me people freeze-drying skittles, gummies, things like that. And so this is right up my current algorithm. Yeah. They look like Cheetos. It looks unique. And I was unaware of freeze-drying candy up until about 10 minutes ago. So very excited to learn about this wild world. I will say the best part about this is seeing people's reaction, eating this for the first time. ASMR. Flavors. It tastes like, texture aside, it tastes just like a gummy worm. Tastes like jello. This is very interesting. Push it against the top of your mouth. Like, I don't like chewing these things. I like pushing them against the top of my mouth and letting them melt. If you just push it with your tongue against the top of your mouth, it does taste a little bit like jello. This is requiring a lot of unlearning because I'm expecting candy, but. All right. Take the red and push it against the roof of your mouth. I still got this. It's red jello. This is fantastic. Let me try the blue side now. I think I'm liking it more with each bite. The first one was a little bit of an exploration for me. I will say out of all the options, the gummy worms are not my favorite. What's your go-to? My go-to is definitely the skittles. They do the wild berry skittles and those ones are really good. The smoothie ones are awesome. Maybe we'll bust those out halfway through. Yeah, we could do that. I don't hate this. I feel like this. Setting myself up here. I'll just follow through. It kind of reminds me of corn dogs. Corn dogs? This is important. When I take a bite of a corn dog, I don't know if I want to continue that journey, but then after it sits there for a moment, I'm like, I need another bite. After you've sat there and you're like, where's that taste? I want that taste back. I feel like I can get a lot of miles out of these. It's the perfect intersection between candy and chips. It has a hearty chip texture to it. Very crunchy, as you could hear through the mics, but still tastes exactly like the flavor is exactly what you'd expect from a gummy worm. It's very interesting. I've never even had anything approximate to what I just put in my mouth. That's what she said. I feel like these would be good in shots. Oh, sure. You want to get the party started? Me saying shots are out for the last segment. Cool. These are fun. Okay. Let's talk about some backpacking stuff. The intro is short because that is essentially what we know about your journey. I'm assuming the bulk of the conversation for today. Give us the background because we've been chatting here for the last 10, 15 minutes or so. The conversation has been very easy. I wouldn't expect that you were hard of hearing. Give us your level or introduce your level of deafness and maybe any tech that's involved. I guess just give us the full background. Yeah, I can give you the full rundown. I was born with CMV. That's a congenital men-something virus. It's a very long word. I always butcher it. I was born with that. That basically meant that I could have been deaf, could have been blind, could have been anything. It could have been missing a leg. It turns out that I was just deaf. My mom, they knew what to look for since they had tested for CMV when my mom was pregnant with me. She was a nurse and she got pregnant. Well, she didn't get pregnant by one of her patients. She got CMV from one of her patients. She just kept on doing what she was doing. They knew what to look for. I was born and I passed a newborn hearing screen. At the time, the newborn hearing screen was just you look at the baby and you scream at it and see if it reacts. Any baby's going to pass a newborn hearing screen. Is that because the volume is loud enough that even if they are hard of hearing, it's still reaching a decibel that they can perceive? Yeah, that they register it basically. That's what they were basing it off of at the time. I was born in 2000. It was not that long ago. I slept through my first fireworks and my parents were like, well, no newborn baby is going to sleep through fireworks. They brought me home and sat me down in the living room and banged a bunch of pots and pans in front of my face. I didn't do anything. Didn't react. They were like, yeah, we have a deaf baby. They brought me back. Were they that calm about it? No. Guaranteed not. I know my mom. They probably sprinted to the hospital. Sure. They did that and then I did a couple of hearing screens and I would pass them again, but then they finally did a sedated one where I was hooked up to a machine and then that showed that I was fully deaf. I got my first cochlear implant when I was 13 months old and my second one when I was five years old. Before you go too far, because I'm going to have questions, cover my questions. I just know it. How did your mom get CMV? How does it get transmitted? Just through contact. She was working on a patient. She's an ER nurse and yeah, I think it was just through contact of, I think it was bodily fluids. So basically, if you're pregnant and you get CMV, then it just goes directly to the child. So she was pregnant when she got it? Yeah. It's not like she could get it and then she goes deaf? Yeah. That can happen? No, no, no. Oh, it can? Okay. Thank God. Yeah, no, that would not be the case. So it just, it went directly to me basically and she didn't see any of the repercussions of CMV. And so I still have it and I still live with it, but I can't transmit it to anybody. And so it's dormant, I guess. How did she know at the time that she contracted CMV? She didn't know right away because the doctor came in and was like, hey, this patient has CMV. And my mom was like, well, I guarantee I already have it now since I've already been working with the patient. So. How could the patient give it to your mom, but you can't give it to someone else? That's a good question. I think it's because it really develops predominantly when you're in the womb versus like, you know, you get it in the womb and it's in that development stages. I'm not a doctor, so, but that's my interpretation of it, I guess. And so, yeah, it just, that means I'm, you know, immunocompromised. I, everything else that comes along with being deaf, I can get into that in a second. But yeah, that's about it with CMV. Were your parents on the lookout for, were they on high alert knowing that she had contracted CMV when she was pregnant, thinking that there was a high likelihood that something could have gone awry? Yeah. I mean, they, the doctors literally had like percentages of the different types of disabilities that I could have. And so they had no idea. And so when I was born and I was just, you know, looked normal, you know, they were like, wow, that's amazing. That's a miracle. And so that was a really cool experience for them to go through. And then also, you know, in a way, it was kind of one of the best of the worst situations. Let me know if this sounds insensitive, because for me, it's purely curious, but I could see how this might not come out how I want it to knowing the array of different things that could have happened. Are you, would you trade being deaf for a different option? Or do you think that like, it's a really manageable, like, I don't know, like, would you trade it? I don't think so. I actually don't think I would trade it for anything. Because for one, I take them out when I sleep, you know, like nothing wakes me up noise wise, you know, I mean, I guess I'm sensitive to vibrations. That's actually how I wake up every day is my bed shakes and it connects to my alarm. And yeah, when I have a headache, I can just take them out, don't have to deal with anything, don't have to listen to anything. So I mean, there are some perks of it. I wouldn't change it now. Have you ever taken them out in a relationship when someone's mad at you? That didn't go over very well. That's amazing. That's the ultimate talk to the hand. Notting along. Yeah. So you mentioned that you wake up to an alarm that vibrates. Is this like an alarm specifically for people, for deaf people? Yeah. Yeah. Actually there's, I've had friends buy it just because they're heavy sleepers. I am ahead. You caught my interest when you said the bed vibrates. Yeah. It's just like a little toggle thing. I don't know. It's probably like three and a half, four inches in diameter. And like, you just put it underneath your mattress and it's just like, it's a sonic vibrator. Yeah. It's like a good April Fool's joke for Garrett. I don't know how to phrase this question. So you got the, your first cochlear implant when you said when you were 13 months old. Yes. And then the second one when you were five. Yes. Do you know how well the implant approximates normal human hearing? Like are you functioning at a hundred percent of what the average person functions at? Is it 75%? Can you, like, what is that, what is it supposed to approximate? Yeah. I mean, they basically say that I hear 15,000 tones and you guys hear 30,000 tones. So I guess that's more on a tonal level, but I don't even know. What does that mean? Like just in terms of different arrays of frequencies. Yeah. If you're listening to music, are you hearing half as much of the range as somebody else? Kind of, it's more like along the lines of, you know, I can't hear like white noise or like the, I guess it's the range of frequencies that I can hear. Okay. So like if it's super deep or like a whale call, that's probably not in my range to be able to hear. Got it. Or if it's like a dog whistle, I know most people can't hear that, but something along those high frequencies, I can't hear. Got it. So there's like that specific range. We used to make that our cell phone ring tone in I would say ninth grade because there was a dog whistle. It was a high pitched frequency because the age that your teachers are, like you start to not be able to hear those high sounds, but when you're super young, you can. I thought you were going to say you knew that the phone was ringing because the dogs were barking. No, no, no. People would set their phones to it because the teachers couldn't hear it. That's funny. Yeah. Okay. So, okay. So you hear at half the frequencies of the average human hearing, but for like this conversation, are you hearing everything perfectly normal? I mean, as normal as I can tell. I was going to say, because like I said, I haven't missed a beat. The conversation hasn't missed a beat since you walked in here. And I didn't know what to expect. And to see that your hearing functions at such a high level is just such a pat on the back to what we're able to achieve with Western medicine and all the technology and everything. If you take out the implants, can you like not hear at all? Zip, nothing. How do they make that work? I know you're not a doctor. We've established this, but how do they make that work? Like how do they just create something where there's nothing? I know that people listening can't actually see this, but so, I mean, what I have here is it's a cochlear implant. So I took my left side off. And so right now I can't hear anything on my left side. And so this part that kind of twists off, that's the battery. And so there's a processor that basically takes sound and it's basically like a camera microphone. And so you know how, when you take a video and you like hear the wind, like it's like, and it's annoying, right? I hear that. And so it's basically kind of like just a camera mic, but then this processor basically transfers those sound waves into electrodes, which are just little electrical pulses. And that goes through a magnet that's actually inside my head. And that magnet has a coil that runs through the cochlea. And so since my deafness comes from like not being able to hear, right? So basically what I'm getting at is I don't have the actual like hairs in the cochlea that stimulate the auditory nerve like you guys do. And so that coil that runs through the cochlea like stimulates it with those electrodes, like it would for you guys with those hairs. Two part question. One, based on what you just said, if I were to put that on, it wouldn't, like I wouldn't hear anything crazy because I don't have the part inside, right? Yeah, nothing would happen. Do you watch Harry Potter? Oh, I love it. The second time I've done this, Zach's out of this conversation. Is this like Fred's like extendable ears? Like could you take the implant and put it under like a door somewhere and go away and it would still go to the part in your head and you could hear really good? Like, can you eavesdrop on people with it? Yeah, actually, if I click on my phone, it connects to my phone and I can turn on live listen and then it just like connects right to my CIs and whatever's going through the microphone on the phone goes directly to my CI. So I could set my phone on this table, go to the other room and I'd hear everything you guys are saying. I feel like this is a superpower. Like this is like CIA shit. Yeah, I do think that's a feature you could do with your phone as well. And that's not as cool. I'm not hearing it in my head. True. You have to use the air pod. So yeah, I guess being able to disguise it, but I am blown away by the tech of that. Just hearing your explanation of it and the fact that you're able to function totally normally with it is amazing. Like, do you feel very blessed that this technology? Because how long has this been around? I mean, there were people who were getting implanted, you know, in the 80s and 90s, but you know, the technology just wasn't there. You know, I was one of the youngest in Iowa to be implanted. And so this was it was basically right when the FDA approved it. Like my mom was on the gun. She went for it. Yeah. Well, she sounds like she's on top of her stuff based on the testing and everything alone. Yeah. And the dehydrated candy. And the dehydrated candy. Wow. So did you ever have to learn ASL or was it just, I'm good with these? Yeah, I did ASL for a little bit. I did it until, I don't know, probably I was roughly kindergarten age and I stopped because I did auditory verbal therapy. And they actually went to the level to where like my audiologist, my auditory verbal therapist, I guess, would make me sit on my hands so that like I wouldn't use my hands to talk. And I just wanted to talk anyway. Like I just stopped using sign language. And my parents were like, well, why are we going to invest the time in learning sign language when he just wants to talk? Yeah. You know, so. So the videos that everyone has seen via social media, always a tearjerker when deaf people get an operation where they can hear like their spouse or their parent or whatever it might be for the first time, is that the operation that they're getting the cochlear implant? Yeah, most of the time. Yeah. So cochlear implant is that like cochlear is a brand. There can be other brands that they do. So there's like Advanced Bionic and that's another popular one. A few other ones that aren't as popular, but cochlear is definitely like the main brand. If someone can't hear and they mainly communicate using ASL, are they someone who hasn't tried a cochlear implant yet or do they not work on certain types of deafness? Yeah, it depends on how you become deaf. That's kind of why I stuttered there for a second when I said, you know, my deafness comes from CMB because if you have damage of the auditory nerve, then the cochlear implant is not going to work at all because that auditory nerve has to be able to sense that there's stuff in the cochlea. And so there's, there are people who have damaged auditory nerves and they're just kind of out of luck. So I don't know, I assume this is true, but this is something that I'm citing as an internet fact that when somebody loses a sense or doesn't have a sense to start with, that the other senses are enhanced. Is that one, an accurate description and two, do you feel like that's true for you? Like, do you have a superior sense of smell or because that you've had the cochlear implant at such a young age, do you feel like you haven't missed out in that capacity? Yeah, that's a great question. I get that one a lot, actually. You know, I do have glasses. I never wear them, but, and I don't think my sense of smell is supersonic or anything. You know, yeah, I don't think my senses are really all that great, to be honest. But yeah, I think it has something to do with the fact that I had my cochlear implants at such a young age. And so I did mention earlier that I was like really sensitive to vibrations when I'm sleeping. So that might be part of the sense that I'm gaining from losing my deafness. Yeah. So, but other than that, yeah, I mean, I don't think I really do. Okay. Does it pivot into backpacking quick? We're going to probably go on a lot of side tracks here, but does it help you sleep at night when you're on trail to be able to take them out? Because then you can't hear like the eerie sounds of nature, or does it make it worse because then you can't hear the eerie sounds of nature? A little bit of both. What I mean by that is because, you know, sometimes, okay, I'll be camping by myself. I do a lot of that and I just take them out and, you know, it just makes me not even think about it because, you know, if there's a bear outside my tent, he just jumps on by. I'm not going to care unless he comes into my tent. That's the other thing that kind of scares me is, you know, I'm in my tent and then a bear comes on in. I'm not going to know until it's on top of me. So, yeah. I think at that point, you're just like, well, God wanted me to go. Yeah, I'd rather not know at that point, I think. Yeah. So I think I lean more on the side of like it helps because then I'm just not thinking about it. Yeah. I don't even like using earplugs because I'm so sensitive to having the feeling of something in my ears, especially when I'm laying down on something. Do you actually feel like, are the implants uncomfortable for you or have you been using them for so long that it just feels second nature? Yeah, it kind of feels second nature. You know, like when I don't wear them, I almost feel naked, to be honest. It's like it's kind of the same concept of glasses. Because I'd imagine it would be so nice to have the option to just turn off all, especially on a windy night. It's not even necessarily the animal sounds, just like the constant inconsistent, almost white noise. That's kept me up so many nights to have the option to opt out of that. It sounds actually pretty sweet. Well, when I camp, like a lot of the times at night, if I can't fall asleep, I'll put in my earplugs and I'll just put them on noise canceling. Like I'm not even listening to music. I just use the noise canceling to try to help with like the twig crack sounds. Yeah. You know, I had people tell me multiple times that they loved camping next to me because then they could just roll around all they wanted in their tent and didn't have to worry about waking anyone else up. That's a good point. Yeah. I will say I can't, on the AT, I hiked for about 600 miles with someone who was deaf and it was hilarious. Like we had a great time. A lot of times it was kind of that where it was like, I know I'm not bothering you, but some of it was just like funny. Like he had a really great sense of humor and I think it just added like an extra element for us. Do you ever like go to a concert and turn the volume up? Because I'm getting to the age now where concerts are too loud for me to be able to control that. You're taking the baby headphones off the twins. To be able to control the volume at a concert, to be like, yeah, turn this racket down a little bit. Is that something that you ever do? I imagine you're controlling the volume on a regular basis. Actually, there's a different settings I can use for different like actual environments. So like when I'm on at a concert, there's a music setting that I can set it to. Wow. And then like if I'm, is that just turning the volume down or what other changes? Yeah. It's just kind of like changing the EQ a little bit to like optimize for music, I guess. Yeah. My audiologist loves it, but I will say the most tragic thing to happen for me at a concert is they die. Oh no. Has that happened? Yeah. Multiple times. Yeah. What concerts? There was a Def Leppard concert I went to in high school. That's a bad one to have. And so you haven't gotten to like the best songs yet because they're not closing and you can see it happen. Oh no. Yeah. At that point you're just people watching, huh? Yeah. Just people watching and then like you're just standing there like, well, this is fun. Do you keep like a set of spare batteries? Like can you, is that a thing? Yeah. I typically bring a spare set, but those of course are the times that I forgot. Yeah. Oh my God. How does one charge get you? Typically it'll get me like 15 hours. Okay. So it's just like, you know, if it's just been a long day, it'll be towards the end of the day that they'll die. Yeah. Is it like, like, let's say you go home. Is it like taking your bra? I know you don't probably take your bra off when you get home, but is it like taking your bra off to take them off? And like, I would imagine probably speak ASL to the people like in your home life to be able to not have to use them for a while. Or is it not like that kind of like, feeling that I'm attributing to taking a bra off? I will say that is something that I would do a lot towards like the first two weeks of school. So like, because if you think about it throughout the summer, you're not really intently listening. You're kind of just doing your own thing. You're having fun, right? And so when you write, when you go back to school, you have to like spend eight hours a day, like really trying to listen. And like for me to actually listen to things and hear things, it takes a lot more effort because I have to like differentiate between different sounds because a lot of the stuff comes in at the same volume. So my brain is kind of adjusted to just kind of focusing in on what I wanted to focus in on. By that, you mean like every background noise. Like if somebody shuffles their chair or you can hear the wind or whatever, a fan blowing, like all that's coming in at the same volume. So it's, you have to be able to discern what you're actually paying attention to. Yeah, kind of. Yeah. I mean, more what I'm getting at is like, you know, fluorescent lights. If it's like above me and it's like buzzing, this one's fine. But, and like someone's trying to talk to me right here and they're both coming in at the same volume. It doesn't, my brain doesn't differentiate it. Yeah, that makes perfect sense. So does this make hiking like the Colorado trail or any trail, does this make just like what might be a mundane making miles part of the hike, like just super wild for you? Cause I imagine being able to hear the leaf cracks, the like tree breeze, like every little thing at the same volume. I just watched all the twilights this past weekend and when Bella got turned to a vampire, she was going through the woods and she was seeing everything super hyper-focused and that was wild. Would it be like that where you're just like hiking and you're just like, whoa, to everything? Cause it's all coming in louder. Or is that just in my head? You know, I think that is, when I was younger, that was a thing. Because then I was like experiencing things for the first time, you know, and being able to like hear different sounds of nature when I was a lot younger was, you know, it was an experience, you know, I wish I could do that again, you know, but yeah, I don't really think so anymore. Just because, you know, I've had these for so long and I've been accustomed to it. It's just, it's just my normal life now. Is there an auditory setting for something like being in the wilderness? Like you mentioned how there's like a music setting. Is there something for being outdoors? I could make a setting. Yeah, probably good. Just basically turn the, you know, higher frequencies down a little bit on my phone and yeah, basically I could. I never have, I usually typically just stay with my everyday setting just because I'm used to it and that's basically the only reason. If you know the first thing about hiking socks, then you are already aware of our next sponsor. Darn Tough is the most trusted sock in hiking and the number one hike sock in the USA. Family owned and made in Vermont, Darn Tough offers the most durable socks guaranteed. In fact, their warranty is famous with hikers because they're unconditionally guaranteed for life. 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Again that code is dtlove-backpackerradioatdarntough.com to get 10% off plus free shipping. This deal is only good for a very limited time so do not wait. Okay let's talk hiking. Oh yeah. So when did the Colorado trail get put on your map? How long have you been hiking? Give us the full like outdoors background. Yeah I've just grown up being outdoors and my mom has taken me out on little day hikes when I was younger and growing up camping. My dad always took me camping a lot when I was growing up and yeah I've always enjoyed it and then I went to college and my buddies and I would go to the boundary waters every summer for a canoe fishing trip and that was always really fun. Did you go to school in Iowa, Minnesota? Yeah I went to school at Iowa State University. Go clones. They've had some good running backs and you weren't there during the Brice Hall years were you? Yes I was. Yeah he's killing it in the Jets. Yeah he's great. I'm watching the 49ers with Brock Purdy right now. Iowa State as well? Yeah. Oh I didn't know that. Yeah that's why. Yeah 49ers have a bad night yesterday or the day before. They've lost a couple games but they're still really good. Just making myself feel better. It was not a good game yesterday. Anyway sorry. Okay so boundary waters in college and then when did the CT get put on your map? Oh yeah so I had a buddy I was just work so I'll back up a second here so I was working in Iowa and I was just I was right after I had graduated college and I had a couple buddies who just went off and you know took like a gap year or I even what really inspired me was I had a buddy who did the PCT and I was like man yeah I really want to do something like that and that really is what inspired me and so I was just like I just googled places in Colorado to go hiking and that's literally all it was and then the Colorado trail came up. Colorado trails. Yeah so what was your longest backpacking trip prior to this? Actual backpacking trip prior to that one would have been like a week in the boundary waters but that was canoeing so I wouldn't even consider that backpacking. Sure. I'd say it was probably just a weekend trip. Okay. Like one or two weekend trips. So what considerations did you have to make for the Colorado trail that maybe someone who didn't have deafness wouldn't have to consider? Like what was it like for you to plan for this trip that set it apart from canoeing or anything different? Yeah I think it was really the battery situation. Trying to figure out how I'm going to keep these things charged because yeah because when I was in the boundary waters I had them dug out because it was so cold and like I forgot to sleep with them. That was a rookie mistake. Always sleep with your batteries. That's very important. Yeah. So is it like your phone where if you are in like my phone it'll do it when I'm at too high of an elevation and it's like exposed and there's cold the phone will just die even if it's fully charged. Yeah. Is it like that with your batteries because they're not really protected much from the elements in your ears. Yeah no that's totally that same thing. Yeah that same concept like I was talking more on like my disposable batteries. The ones I have on right now are my rechargeable batteries. Oh. And so I had a little fob that I could like connect to the portable battery charger and that's what I predominantly used but it broke on me and so I had to use the actual batteries and they dutted out in the boundary waters because it was so cold and that was one big thing that I was really worried about for planning and then yeah it actually happened to me again on the Colorado Trail and I just ended up having another resupply box that had extra batteries in it and so it worked out but I almost went a week without being able to hear on trail. So it gets so cold that the battery just breaks like it's not you can't warm it back up and recharge it. Yeah the so they're like zinc air batteries is what they're called and like when they're exposed to a certain temperature then it just like duds out. Hmm. Yeah it's super weird. When you're talking about disposable batteries are you talking about just like our standard AAAs or are there like how you just unclicked that battery from it? Is it that but you just toss it after each use? Yeah it's kind of like that so there's like a little sheath that comes out and then it holds you know those little like little little batteries. Yeah like the watch ones? Yeah kind of like those that's basically what they're used. So the disposable parts that little circle battery. Yeah. Got it. Yep. So what was it like you said it was a were you a week without proper battery for the? I almost was a week without it but then. It happened to happen at the your resupply. Yeah then I happened to find them at the bottom of my resupply box. Got it. Like thank you. Yeah so did you go imagine something like a half day from the time that it broke to get to town to actually get your resupply? Yeah actually one of them died and all the other so I had my right one which is my favorite one because I had it first and so I favor that side more and so I had that one working and then no more batteries left and then my left one was dead so I'm like well crap I know I have half a day before I can't hear at all. Is it really disorienting for it to only work in one ear because uh you know Apple AirPods sometimes the like the old ones like one of them just won't charge even if it's sitting in the dock so I've been at the gym before where I'm listening to music through one AirPod and for me it's really distracting like I feel like my workout sucks just because I'm so thrown off by having the inconsistent audio is that I imagine for you it's significantly worse. Is it pretty distracting for it only to be registering audio on one side? You know for like the first second it is and then it kind of just goes back to just all right well I know that that's the only side that sounds coming from so I got to tilt my head a little more that way and just kind of unconsciously adjust but yeah I mean other than that yeah I mean it's it just really does suck when that happens in inconvenient times like a concert. How do you handle that when it's on trail because there's a quote I was trying to look it up quick enough but there's a quote from a book I've mentioned on here countless times Spark the Revolutionary New Science Between Exercise and the Brain I highly recommend it still great book but they talk about people that are I think it was in this book they talked about it people that are left alone like to their own thoughts and how a percentage that's higher than I would have expected of these people would rather be like subjected to mild electric shocks than left alone with their own thoughts and like no other noise for you know a day longer you know it was 15 minutes I think is what the study was it was super small and it basically was just going to like back this evidence that like people aren't comfortable spending time with themselves like in their own thoughts that sort of thing to to lose hearing on a trail and to have to go like a day two days even when you were talking about the canoeing trip however long that was before getting it back how is your mental like overall wellness adjusting to I mean I assume in these settings where they're doing these studies they have the choice like I can quit the study I can leave the room I can go hear things and I've seen people on trail where they haven't talked to anyone in like five days and they look different how how do you see that happen and take something like that that happens to you on trail and a what does it do to you mentally and b how do you combat not being able to flip that back on yeah it's a really interesting thing because you know there's weekends that I'll go camping and I'll just not have messy eyes on and for me it's a place that I can really just think things through and be by myself and so I actually do enjoy that time and I you know I'm an introvert I'm an extrovert you know I guess I'm a little more of an introvert now just since COVID and everything else you know I do like being on my own now and just kind of taking them off and being in my own little world because that's really what it is I'm in my own little world and so I guess like on a trail sense you know it does get a little scary at first because then you're like when the first time that it happened where like they died on trail and I was just like almost a day without being able to hear outside I was just constantly like panning my surroundings just constantly because you know I don't know if there's another hiker coming along I don't know if there's you know I'm gonna run come up on something that might not be very friendly so yeah there's definitely times that it is a little scary but I've become accustomed to it. To that question did you have anyone that you could reach out to as a resource prior to the CT who was deaf that you could ask these questions to? I had nobody I just kind of figured it out figured out as I went nobody I knew who was deaf had ever done anything like this I guess and so I just I'm a big fan of just going for it. It's a good attitude. Is there any sort of community Facebook group whatever platform it might be where you have access to other people where you could ask this question and you're like hey has anyone done long-distance backpacking and everyone's just crickets? Yeah I mean there's actually a couple different Facebook groups where there's you know families who have cochlear implants they can like the parents can talk on there and I actually grew up attending a cochlear implant family camp and so I met a lot of people from all over the United States who also had cochlear implants because you know growing up in Iowa small town Iowa you're not going to have anybody in a 100 mile radius who's also deaf. You mentioned before we hit record that your graduating class was 23 people? 28. 28. No short you those five people yeah so you get a small town. What was the population of your town? Oh probably like a thousand people okay yeah it's small yeah it's pretty small I mean it was literally yeah like 30 minutes away from Des Moines. Are there any trail specific groups like Facebook groups that are long-distance focused for people that have like hearing disabilities? No not that I know of that's a good idea though I might do that tonight. Well I mean I hiked with Mr Perfect and he was deaf and then he had a friend that we spoke to several times that wasn't hiking but she came to trail day so I had met her too and I know there's a few others that have like come across the radar but I think that would be a great resource for like you guys to have with each other. Just before we move too far off the your your implants die while hiking how do you handle that topic? A lot of things that you'll hear when people aren't thriving at a long-distance hike like a lot of it comes down to all the alone time right like there's so much time with your own mind there's so much time where you're not stimulated by other things and I think when we're just constantly fed just like social feeds to scroll through content here and there a tv on in the background that's where like you start to see people like I mentioned the one who hadn't talked to someone for five days where they just seem unwell right like they're not doing good and I know that can bring a lot of people off trail as someone who will go weekends where you just take them out and actually enjoy it do you have tips for people for hiking without sounds to keep them stimulated while hiking or to make it seem less jarring for them like are there things they can do that make it better if they're not one that usually thrives in that setting? Yeah I mean I would say first off you gotta like your inner monologue you know you gotta be best friends with your inner monologue because otherwise it's gonna be a battle you know because if you aren't best friends with your inner monologue then you're gonna be just you know fighting each other and really what it comes down to is are you comfortable by yourself and if you're kind of uncomfortable in those settings and you know you just kind of gotta go back to you know why does it make you uncomfortable because there's probably a reason and there's probably something deeper that stems from that. How did you get comfortable with yourself? I assume based on my this is based on me but I assume not everyone's born comfortable with themselves I assume it takes effort assuming you're not just naturally comfortable with yourself how do you get there? Oh man that's a tough one. That's a deep question. That's very deep. Now you have to give us therapy. Making it easy for Zach's follow-up. I don't know it just seems like you're doing really well with it. Yeah well I appreciate it I appreciate it yeah I mean I um what I kind of did was I just you know took it step by step you know because I first day that happened to me and I just kind of you know I couldn't do anything about it you know I didn't have my garment yet and so you know that would happen a lot growing up you know I'd be at school and they would die and I wouldn't have batteries I have to go the rest of the day without being able to hear and so I guess just that those little moments of exposure of you know have being forced to be by yourself in your own little world that kind of culminated to an extended period of time that can happen. So like doing a shakedown hike but like a quiet yeah shakedown like a yeah like do do little shakedown hikes basically where you like maybe first day you go by yourself and then the second day you have a friend that comes out and meets you um that's that'd be a good way to do it or vice versa where you go out with two people and then you just you stay an extra day by yourself. I was thinking even smaller like just sitting on the couch without using my you know like before you even go outside just sit there and don't touch the phone for an hour you know yeah yeah yeah definitely don't touch the phone. Do you have to worry about them getting wet like is it a concern if it's raining outside? Oh yeah yeah yeah it's like they're more water resistant now but yeah back in the day like you had to take them off like it was super sensitive to water and one thing I'll say about that camp that I grew up going to is they had a pool party every year and if you imagine this scenario where you put a bunch of deaf people into a pool and they don't have waterproof stuff yet the lifeguards are gonna love you because they're blowing their whistles they're doing all that they can and you no one in the pool is even listening to you they can't hear you and so I mean like it's just crazy to see how technology has advanced because you know when you go to that camp now everyone has their waterproof stuff on and so like yeah now it's a little more waterproof or resistant than it was. What areas would you like to see improvement with the tech like you mentioned that it's advanced from like a waterproofness standpoint what areas do you see it could potentially still have room for improvement? Oh yeah I mean it's improving every year there's another upgrade that I could get and so basically what they're doing with their new upgrade now is you can go to an airport and it'll automatically connect to the bluetooth there and they'll tell you like when you're boarding and all that and you can connect to any bluetooth device basically. Can someone hack your mind then? I hope not. Can I just like how the airport would bluetooth to your sounds can I bluetooth to it and be like I'm in your head you know like is that a possibility? I'm not saying it's crazy I'm saying it's scary. I feel like that's very possible. Yeah yeah that's definitely possible I don't know I hope not but uh that'd be scary. Are you excited about those advancements or is that kind of like freaky because that kind of freaks me out a bit? Yeah I mean I'm excited because I mean they're doing it in the right mind I hope so. Yeah it seems out of kindness. Yeah I mean out of kindness I hope but yeah I mean other than that I mean I don't know because like it seems like each model that they make it gets smaller and smaller and they actually have one now where it's without the actual processor that goes on your head but the magnet and it's just the little magnet it's like that big. That's interesting because I'm thinking of this from the standpoint of like just getting you to the point where you can hear like the normal person the person with normal hearing but what you're describing are enhancements that are even beyond what somebody with that level of hearing has. I guess it opens up a whole train of ideas for ways that it could you could be enhanced beyond you mentioned being able to know when you're boarding but there's probably infinite possibilities in that standpoint. Yeah tons I mean like it would be really cool to just have like a little like basically you don't even have to wear your processor every day but it's like all internal then you like wear your processor to charge it kind of like air charge or like you know you have your little pod that you set your phone on and it automatically charges without having to plug in like that'd be kind of cool. Yeah because I remember for a while sorry to cut you off Jones but you're probably more relevant than mine. For a while the buzzword was augmented reality and we're seeing this now with like Google Glass and now Apple's got this too about like the way that you visually interface with the world and it giving you more context than you would otherwise have. From an auditory standpoint thinking of hiking like if you heard like a bird call and that's what I was saying about nature being wild. Yeah being able to have the implant be like oh that is the blue-footed booby. Oh that'd be so cool. That's that goes back to your Tony Stark stuff where you wanted the Iron Man suit. Totally. That's a feature the Iron Man suit. Well I was gonna ask on the same realm of wild like if there's any upgrades that have been made yet where it can hear different languages and it still transmits English to you. No there hasn't been one of those but there has been one I actually really don't like this setting. I currently have it but I don't have it turned on and what it does is it's called like zoom and so if there's like a crowd of people around me and I face this one person that I want to listen to it'll like zoom in on that person that I want to listen to and it'll kind of cut everyone else out but yeah it doesn't really work when you're like in a basement and like your mom or whoever screams from the first floor then because then it's like well it's listening to the air conditioner but then it doesn't quite know if that other sound coming from somewhere else. It doesn't know what to focus in on. Yeah then it just kind of screws it up. Right. This is going to be probably my dumbest question of the night. Yeah. I don't know it's hard to ever tell. The night is young. We got time. Do people ever use these that don't need them like if you're not hard of hearing is because I feel like some of the stuff you're saying sounds really like I'm kind of not like not jealous obviously I'm very grateful for the hearing I have but it sounds really cool to be able to zoom in on certain things and make things louder like I struggle when there's a lot of noises going on at once. Yeah. Are there people that use these things that don't need them because it's just like like really cool or strategic? I don't know. I just feel like that's it sounds like a superpower to me. It is you know I mean to an extent yeah it is a superpower. I mean with technology the way it is now if you told someone in the 1800s what I could do they'd be like what planet are you from? Yeah. So it's insane to think about but um no I haven't really known anyone just because the fact that insurance is such a battle um especially back in the day like when I first got them my mom was she's the rock star like she wrote letters on letters on letters just to get insurance approval. How much do they cost? I mean we were paying oh shoot I mean they're probably I probably have like I don't know half a million dollars in my head. Shut up. No. Just the part that's inside? Oh all of it like external internal surgery everything yeah. Wow. Does the implant itself I'm thinking like fake joints they have a lifespan of 20 years is this something that has to be refreshed on a on a bait on a consistent basis? Yeah the they gave the internal stuff like 18 years okay and I'm well past that I'm 23 um and so it's kind of like any day now I asked my audiologist like what she thought would be kind of when I'd need to be re-implanted um and she's just like you know it could be 10 years from now could be you know five years from now it could be next year. Is the only consideration that the sound part stops is it not like the the stuff that makes it like deteriorates the grades gets absorbed by brain goo? Yeah. I don't know how I don't know how a lot of things work. Oh it's all good it's all good yeah I mean it's just really like the lifespan of the technology if it is able to last that long um internally um because those internal devices don't get touched you know because you have surgery to get them put it in and then that's it. When you switch to a new one is it going to be like getting the same thing like you leave the same person as you entered or is it like upgrading like your you know 97 Toyota Camry to the newest Range Rover? It'll be like upgrading kind of like to a Range Rover because it'll be different technology there'll be because nowadays it's just an outpatient there like procedure when I got them like I had to stay in the hospital for a couple days and I had this big old bandage around me and like it was it did not look pretty I had like these big scars and now you know it's just a little slit behind the ear and then they slide the little magnet in and they're able to do everything with the cochlea all within an outpatient procedure. Can you feel it? Yeah I mean can I touch it? Yeah. So is that where the cochlea is like that far above the actual ear or is it I thought the cochlea was inside the ear? I don't feel it because it's right there yeah so it's it's it's like a slight little bump there but um yeah so that's how it's held on to my head is a magnet. Wow. Yeah you mentioned at the top of the interview that there were other um ramifications I'm not sure of being deaf or you say CMV was the yeah can you look that up yeah yeah it's bothering me so much. Cytomegalovirus? Yes that's it yes. Okay okay you mentioned that like um that your immune system is compromised because of is that because of the deafness or because of the virus itself? I'd say that one was because of the virus itself okay um and so like growing up like I would brush my teeth twice a day like every other kid right but I would get cavities on cavities yes I had to convince people growing up that I brushed my teeth twice a day and floss every day because I would just keep getting cavities and you know it just yeah so they think that has something to do with CMV like a weak um enamel basically um and then like the part that comes with the deafness is I don't have balance so I don't have the liquid in the semicircular canals that give people balance and so like how does that play out I'm very clumsy well there's some like steep I mean there's not like I don't like steep things there's not scary stuff on the Colorado trail but there's some there are some ridges yeah does that like screw you up well definitely um there was actually when we got to the high point of the Colorado trail we did an alpine start um and that was actually my first 30 mile day that was that was awesome my trail family is awesome for pushing me to do that but anyway so we woke up at like 2 30 in the morning and started hiking and it was complete darkness you know but the stars were out and that was kind of helpful but I had to have my headlamp on like the brightest it could go and even with that I was using my trekking poles side to side basically holding myself up walking on basically four legs just to stay up with the rest of the trail family yeah are there other so you mentioned the battery's dying you mentioned uh balance being a challenge are there other things that are not obvious that would be make something like this more challenging um yeah I think it would just be really the clumsiness um that's a really big thing and another one that a lot of people don't think about is swimming s

Klaus Früh visits the Incubator to discuss his career and his work on cytomegalovirus-vectored vaccines which are unique in their ability to persistently maintain an immune shield of effector memory T cells, including highly unconventional MHC-II and MHC-E restricted CD8+ T cells. Host: Vincent Racaniello, Rich Condit, and Brianne Barker Guest: Klaus Früh Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Spike shirts at vaccinated.us (promo code Microbetv) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) HCMV-based attenuated vaccine platform (Sci Rep) HLA-E-restricted, Gag-specific CD8+ T cells suppress HIV-1 infection (Sci Immunol) RhCMV/SIV vaccine shows long-term efficacy against SIV challenge (Sci Transl Med) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

On episode #39 of the Infectious Disease Puscast, recorded at IDWeek in Boston, Daniel and special host Priya Kodiyanplakkal review the infectious disease literature for the weeks of 9/27 – 10/12/23. Host: Daniel Griffin and Priya Kodiyanplakkal Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Survival from rabies in a young child from India (AJTMH) The perils of overly-sensitive viral load testing for persons living with HIV (OFID) Letermovir vs Valganciclovir for prophylaxis of Cytomegalovirus in high-risk kidney transplant recipients (JAMA) Frailty and survival in the 1918 influenza pandemic (PNAS) Adverse pregnancy outcomes among HIV-infected Women taking isoniazid preventive therapy during the first trimester (CID) Ceftobiprole for treatment of complicated Staphylococcus aureus bacteremia (NEJM) Real-world application of oral therapy for infective endocarditis (CID) Efficacy and safety of sulbactam–durlobactam versus colistin for the treatment of patients with serious infections (The Lancet) Information delay of significant bloodstream isolates and patient mortality (CID) Critical appraisal beyond clinical guidelines for intra-abdominal candidiasis (CC) Update on outbreak of fungal meningitis among Americans who received epidural anesthesia at clinics in Mexico Increasing prevalence of artemisinin-resistant HRP2-negative malaria in Eritrea (NEJM) Gender differences in psychosocial determinants of hand hygiene among physicians (ICHE) Music is by Ronald Jenkees

Guest: Valerie James Abbott - If you work as a pediatric speech-language pathologist with the birth through 8-year-old population on speech sound disorders and/or language acquisition, this is the hour for you. Valerie is here to educate us all on potential risk factors for late childhood onset hearing loss, including the dangers of the cytomegalovirus. Did you know that this virus can appear as a common cold for the mother during pregnancy, can only be tested for shortly after birth, but may lay dormant for years, then result in devastating hearing loss when the little one is entering school? Hold hope, though! Valerie will share the initiatives that are occurring by various organizations across the country to advocate for change to catch this type of hearing loss and intervene earlier.

Valganciclovir is standard cytomegalovirus (CMV) prophylaxis in high-risk kidney transplant recipients, but its use is limited by myelosuppression. JAMA Deputy Editor Preeti Malani, MD, MSJ, interviews Ajit Limaye, MD, from the University of Washington, about a multinational randomized trial of letermovir vs valganciclovir for CMV prevention in CMV-negative patients receiving a kidney from a CMV-positive donor. Related Content: Letermovir vs Valganciclovir for Prophylaxis of Cytomegalovirus in High-Risk Kidney Transplant Recipients

Local mom and public health professional Cara Gluck joins us to recognize June as Cytomegalovirus (CMV) Awareness Month. This virus affects 1 in 200 babies born in the United States and can have long-term, significant developmental impacts on a baby if a mom contracts the virus while pregnant. Cara joins us to share her family's journey with CMV, simple steps pregnant moms can take to reduce their risk and what all parents-to-be need to know about the virus.

On episode #30 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the weeks of 5/24 – 6/7/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Foodborne illness outbreaks at retail food establishments (CDC) Donor-derived fulminant herpes simplex virus hepatitis after liver transplantation (TID) High-dose influenza vaccine is associated with reduced mortality among older adults with breakthrough influenza (CID) Letermovir vs valganciclovir for prophylaxis of cytomegalovirus in high-risk kidney transplant recipients (JAMA) Association between combination antibiotic therapy as opposed as monotherapy and outcomes of ICU patients with pneumonia (CC) Safety of Streptococcus pyogenes vaccines (CID) Meningococcal ACWYX conjugate vaccine in 2 to 29 year olds (NEJM) Orthopaedic surgical management of pressure-ulcer related pelvic osteomyelitis (OFID) On culture and blood cultures (CMI) Benchmarking of outpatient pediatric antibiotic prescribing (JPIDS) Outbreak of suspected fungal meningitis in US patients who underwent surgical procedures under epidural anesthesia (CDC) Risk of systemic fungal infections after exposure to wildfires (The Lancet) Giardia duodenalis and dysentery in Iron Age Jerusalem (Parastiology) Community water fluoridation levels to promote effectiveness and safety in oral health (CDC) Music is by Ronald Jenkees

FDA revoke Emergency Use Authorization for a COVID-19 vaccine; New approval for treatment of iron deficiency in patients with heart failure; Lumryz now available for excessive daytime sleepiness; Vowst approved for C. difficile infection; Prevymis approved for prophylaxis of CMV disease in adult kidney transplant recipients.

Addressing the needs of a child born with congenital cytomegalovirus (CMV) infection    Credit available for this activity expires: 5/19/2024 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/992168?ecd=bdc_podcast_libsyn_mscpedu

The Root Cause Medicine Podcast is created by Rupa Health, the best way to order, track & manage results from 30+ lab companies in one place for free. The Root Cause Medicine Podcast is a weekly one-on-one conversation with renowned medical experts, specialists, and pioneers who are influencing the way we look at our health and wellbeing. This week we're joined by Dr. Kalea Wattles, Associate Director of Curriculum at The Institute of Functional Medicine (IFM). In this episode, Dr. Kalea Wattles explains all about reproductive longevity, including the fertility span, testing for fertility, and how to slow down ovarian aging. Dr. Kalea Wattles is an accomplished naturopathic doctor, certified functional medicine practitioner, and a renowned fertility expert. Her approach to helping women conceive and maintain pregnancies is based on the functional medicine philosophy. Key Takeaways: Focusing on reproductive longevity It's a human-specific phenomenon to experience a decline in fertility potential around middle age. This could be attributed to the "grandmother hypothesis," where women lose their fertility at a young age to allocate time and energy to taking care of their offspring. Nevertheless, losing reproductive potential has broader implications for various bodily systems, such as reduced bone mineral density and cognitive function, and an increased risk of cardiovascular disease. Therefore, it's essential to prioritize reproductive longevity to not only ensure successful pregnancies now, but also promote long-term health and vitality. Understanding lifespan, healthspan, and fertility span Lifespan is the total duration of a person's life, from birth to death. Healthspan, on the other hand, refers to the period of life during which an individual is in good health and free from chronic diseases or disabilities. It's a measure of function rather than a measure of time. The fertility span is the period during which an individual is capable of reproducing, and it refers to the health of the ovaries, regular ovulation, hormone production that protects your bones and brain, and the nervous system. Normal versus pathological ovarian aging Women's ovaries naturally age, leading to a decline in function that culminates in the menopausal transition, usually occurring in the early fifties. This process is a normal part of aging and occurs regardless of a woman's overall health. However, some women experience an acceleration in ovarian aging, resulting in a decrease in ovarian reserve, which can lead to infertility. This can occur even if the woman is still having menstrual cycles and normal hormone levels. Premature ovarian insufficiency is another condition in which the ovaries exhibit perimenopausal or menopausal symptoms, such as irregular periods, even in younger women. Oxidative stress and inflammation Oxidative stress and inflammation are the two biggest contributors to ovarian aging. Oxidative stress is when the body experiences a buildup of compounds that can damage DNA. It can be from having a high sugar diet, environmental toxin exposures, chronic inflammation, or a low intake of dietary antioxidants. Inflammation can come from lots of different sources. Periodontal disease is a significant contributor to inflammation in the reproductive system. But it can also come from food sensitivities, intestinal hyperpermeability, or leaky gut. It's crucial to acknowledge the interconnectivity of all the systems in our body, as each one can impact the others. Therefore, when a woman intends to get pregnant, she must ensure that all her bodily systems are in proper working order and balance. Slowing ovarian aging Be mindful of your diet and reduce sources of advanced glycation. This means cutting back on fried and baked foods and focusing on consuming more antioxidant-rich foods. In addition to dietary changes, it's also important to consider lifestyle factors such as exercise, stress management, and adequate sleep. Also, regularly test. Also, check out Dr. Kalea's recommended lab testing: Hormones testing, Luteinizing hormone test, Follicle-stimulating hormone test, Testosterone panel, DHEA-S Test, Progesterone testing, Thyroid testing, TSH testing, Free T3 test, Free T4 test, Reverse T3 test, Thyroid antibodies test, Comprehensive metabolic panel, Lipid panel, High-sensitivity C-reactive protein test, Hemoglobin A1C test, Fasting insulin test, Nutritional testing, Vitamin D testing, B vitamins testing, Celiac panel, Ferritin test, Iron test, Homocysteine test, Infectious screening, HIV test, Syphilis test, Chlamydia test, Gonorrhea test, Hepatitis test, Cytomegalovirus test, EBV test, Salivary cortisol test, Comprehensive stool analysis, Micronutrient testing Order tests through Rupa Health - https://www.rupahealth.com/reference-guide

Socioeconomic Disparities of Cytomegalovirus    Credit available for this activity expires: 4/28/2024 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/991326?ecd=bdc_podcast_libsyn_mscpedu

Are you and your patients up to date regarding cytomegalovirus (CMV)? Disease burden, patient screening, and education in a nutshell. Credit available for this activity expires: 4/12/24 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/990638?ecd=bdc_podcast_libsyn_mscpedu

Interview with Upstate research scientist Gary Chan, PhD

Please visit answersincme.com/BZR860 to participate, download slides and supporting materials, complete the post test, and obtain credit. In this activity, an expert in pediatric infectious diseases discusses prevention of congenital cytomegalovirus (cCMV). Upon completion of this activity, participants should be better able to: Recognize the disease burden of congenital cytomegalovirus; Describe the rationale for novel vaccines in preventing congenital cytomegalovirus; and Outline evidence-based strategies to improve neonatal outcomes in congenital cytomegalovirus.

Please visit answersincme.com/BZR860 to participate, download slides and supporting materials, complete the post test, and obtain credit. In this activity, an expert in pediatric infectious diseases discusses prevention of congenital cytomegalovirus (cCMV). Upon completion of this activity, participants should be better able to: Recognize the disease burden of congenital cytomegalovirus; Describe the rationale for novel vaccines in preventing congenital cytomegalovirus; and Outline evidence-based strategies to improve neonatal outcomes in congenital cytomegalovirus.

On episode #23 of the Infectious Disease Puscast, Daniel and Sara review the infectious disease literature for the previous two weeks, 2/16 – 2/28/23. Hosts: Daniel Griffin and Sara Dong Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of Puscast! Links for this episode Association between cytomegalovirus infection and tuberculosis disease (JID) In-depth virological and immunological characterization of HIV-1 cure after allogeneic hematopoietic stem cell transplantation (Nature) Algorithm-based Clostridioides difficile testing as a tool for antibiotic stewardship(CMI) Clinical utility of nasal surveillance swabs in ruling-out MRSA infections in children (JPIDS) Antimicrobial for 7 or 14 days for febrile UTI in men (CID) Treatment strategy for rifampin-susceptible TB (NEJM) Current pyuria cut-offs promote inappropriate UTI diagnosis in older women (CID) Efficacy of doxycycline for mild-to-moderate community-acquired pneumonia in adults (CID) Hospitalizations for unspecified mycoses and implications for fungal disease burden estimates (OFID) Invasive mold infections following Hurricane Harvey (OFID) Cryptococcal meningitis and clinical outcomes in persons with HIV (CID) Rapid range shifts in African Anopheles mosquitoes over the last century (Biology Letters) Neuroangiostrongyliasis: Rat lungworm invades Europe (ASTMH) Balamuthia mandrillaris encephalitis presenting as a symptomatic focal hypodensityin an immunocompromised patient (OFID) Low rates of antibiotics prescribed during telehealth primary-care visits persisted during COVID19 (ICHE) Music is by Ronald Jenkees

Few people are aware of cytomegalovirus, referred to as CMV, even though more than half of Americans are infected with it by the age of 40, according to infectious disease expert Laura Gibson, MD'94, in a new Voices of UMass Chan podcast. For more information about CMV, visit https://www.nationalcmv.org or www.nowiknowcmv.com.

Felicia joins TWiV to discuss her career and her research on human cytomegalovirus, which infects most of us for our entire lives yet mainly causes disease in the immunosuppressed. Hosts: Vincent Racaniello, Alan Dove, and Brianne Barker Guest: Felicia Goodrum Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode •Research assistant position at FDA (pdf) •The loss of binary (Curr Clin Micro Rep) •Virology in Peril (mBio) •Letters read on TWiV 973 •Timestamps by Jolene. Thanks! Weekly Picks Brianne – “Leukocyte” immunology video parody Alan – West Point Removing Confederate Monuments, and Ty Seidule's book on that subject Vincent – The works of Haruki Murakami – South of the Border, West of the Sun; also short stories (First Person Singular, particularly Confessions of a Shinagawa Monkey; and Men Without Women, particularly Drive My Car) Listener Picks Karen – On All Fours: Transient Laborers, the Threat of Movement, and the Aftermath of Disease Kevin – James Hoffmann and Bald and Bankrupt Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

Cytomegalovirus is VERY common and VERY contagious. Chances are you may have caught it already and if not, you will. Some people get over it pretty quickly. And for others, it causes chronic fatigue. In this episode, I break down the acute and chronic symptoms of cytomegalovirus (CMV) and how you can get tested and eliminate it from your body to get your energy and health back. Find out more: https://integrativemedica.com --- Send in a voice message: https://podcasters.spotify.com/pod/show/jake-schmutz/message

DR. IRVING KIRSCH ON 60 MINUTES PROVING PLACEBOS WORK AS GOOD OR BETTER THAN PHARMACEUTICAL DRUGS Qatar: Killer Heat Cripples Workers India on Fire: Dealing with the heatwave crisis   Higher vitamin C levels associated with lower mortality risk during 16-year period Chinese Academy of Medical Sciences, August 20 2022 A study reported in the Journal of Epidemiology and Community Health has uncovered an association between higher plasma vitamin C levels and a lower risk of mortality during more than 16 years of follow-up.  The study included 473 men and 475 women between the ages of 53 and 84.  Among subjects whose plasma vitamin C concentrations were among the top 25%, the adjusted risk of dying from any cause during follow-up was 25% lower than the risk experienced by subjects whose vitamin C levels were among the lowest quarter. Those whose plasma vitamin C levels were among the highest 25% had an adjusted risk of dying from cancer or stroke that was 28% lower and a risk of dying from heart disease that was 35% lower than subjects whose levels were lowest.  When subjects with low vitamin C levels (defined as 28 micromoles per liter or below) and normal levels (greater than 28 micromoles per liter) were compared, a normal level was associated with a 23% lower risk of premature mortality and a 38% lower risk of dying from heart disease, in comparison with low levels.  As a possible reason for their findings, Shao-Ming Wang and colleagues note that oxidative stress is lowered by vitamin C. Oxidative stress can promote endothelial dysfunction that underlies heart disease by increasing inflammation and lipid peroxidation and decreasing nitric oxide availability. Oxidative stress also causes DNA damage associated with cancer. Pomegranate-cocoa blend helps improve aging men's symptoms Shetty Hospital (India), August 19 2022.  A study published  in the International Journal of Medical Science found benefits for supplementing with a combination of extracts of Punica granatum (pomegranate) fruit rind and Theobroma cocoa seed extracts in middle-aged men. Previous research that investigated the effects of a blend of extracts of pomegranate fruit rind and cocoa seed in young men resulted in increases in serum and free testosterone levels as well as muscle strength and size. The current study included 120 men between the ages of 36 to 55 years who received 200 mg or 400 mg of pomegranate-cocoa extract or a placebo for 8 weeks. All participants were assigned to a program consisting of 30 minutes of walking per day for 5 days per week.  At the end of the 7-week period, both doses of pomegranate-cocoa extracts were associated with significant improvement in aging males' symptom scores, free and total testosterone levels, strength and perceived stress compared to the beginning of the study and to the placebo group.  The authors concluded that pomegranate-cocoa “is a well-tolerated, safe, and effective nutraceutical blend that boosts sexual function, testosterone level, and psychological and general well-being in aging males.” Placebo effect demonstrates healing power of the mind Harvard Medical School, August 13, 2022  Experts at Harvard Medical School advocate that the placebo effect be received with more positivity, rather than viewed as a deceptive or inaccurate measure designed to test health.  They conclude that the power of thought can be extremely effective in helping people heal, focusing on physiological changes that have been linked to the placebo effect. The placebo effect involves someone being given medicine that is actually typically nothing more than a sugar pill which does not contain active ingredients. Many times, patients receiving a placebo who are in need of healing a certain condition report feeling significantly better, if not altogether healed. The experts at Harvard explain that improvements may take place because of the anticipated response that a person expects when given medication. The university's literature says that there is “evidence that some of the placebo effect is a favorable reaction to care and attention from people who patients believe can help ease their suffering and distress.” It goes on to say that the placebo effect “may be an integral part of good medical care and an ally that should be embraced by doctors and patients alike.” This paves the way for potential changes in how health is handled and, furthermore, reinforces the strength of the human mind to bring about healing and desired outcomes, health or otherwise. Awake within a dream: Lucid dreamers show greater insight in waking life University of Lincoln (UK), August 12, 2022 People who are aware they are asleep when they are dreaming have better than average problem-solving abilities, new research has discovered. Experts from the University of Lincoln, UK, say that those who experience ‘lucid dreaming' — a phenomena where someone who is asleep can recognise that they are dreaming — can solve problems in the waking world better than those who remain unaware of the dream until they wake up. It is thought some people are able to do this because of a higher level of insight, meaning their brains detect they are in a dream because events would not make sense otherwise.  This cognitive ability translates to the waking world when it comes to finding the solution to a problem by spotting hidden connections or inconsistencies, researchers say. The research by Dr Patrick Bourke, Senior Lecturer at the Lincoln School of Psychology, is the first empirical study demonstrating the relationship between lucid dreaming and insight. The study examined 68 participants aged between 18 and 25 who had experienced different levels of lucid dreaming, from never to several times a month. They were asked to solve 30 problems designed to test insight. Each problem consisted of three words and a solution word. Results showed that frequent lucid dreamers solved 25 per cent more of the insight problems than the non-lucid dreamers. The role of dietary coconut for the prevention and treatment of Alzheimer's disease Curtin University (Australia), August 12, 2022 According to news reporting originating in Bentley, Australia, research stated, “Coconut oil, derived from the coconut fruit, has been recognised historically as containing high levels of saturated fat; however, closer scrutiny suggests that coconut should be regarded more favourably.” The news reporters obtained a quote from the research from Curtin University, “Unlike most other dietary fats that are high in long-chain fatty acids, coconut oil comprises medium-chain fatty acids (MCFA). MCFA are unique in that they are easily absorbed and metabolised by the liver, and can be converted to ketones. Ketone bodies are an important alternative energy source in the brain, and may be beneficial to people developing or already with memory impairment, as in Alzheimer's disease (AD). Coconut is classified as a highly nutritious ‘functional food'. It is rich in dietary fibre, vitamins and minerals; however, notably, evidence is mounting to support the concept that coconut may be beneficial in the treatment of obesity, dyslipidaemia, elevated LDL, insulin resistance and hypertension – these are the risk factors for CVD and type 2 diabetes, and also for AD. In addition, phenolic compounds and hormones (cytokinins) found in coconut may assist in preventing the aggregation of amyloid-beta peptide, potentially inhibiting a key step in the pathogenesis of AD.” According to the news reporters, the research concluded: “The purpose of the present review was to explore the literature related to coconut, outlining the known mechanistic physiology, and to discuss the potential role of coconut supplementation as a therapeutic option in the prevention and management of AD.” Cold sores virus, cardiovascular damage linked in study Brighton and Sussex Medical School, August 14, 2022 A herpes virus similar to the one that causes cold sores has been linked to immune cells that can damage cardiovascular tissue, according to a study. Researchers at the Brighton and Sussex Medical School in England found that a relevant number of a specific type of immune cells arise when infection with cytomegalovirus is present. Their findings were published in the journal Theranostics. The virus, which is frequently associated with the salivary glands, has been considered harmless because the immune system usually controls it. But the CD28null CD4 T-cells have been known to be involved in damaging the arteries around the heart. Cytomegalovirus infection increases the risk of cardiovascular death by over 20 percent, according to a study published last year in the Journal of the American Heart Association, but the effect wasn't identified. One theory was they were a natural consequence of aging. “While we had previously been aware of a link between these immune cells and cardiovascular damage, this study is the first to show that sufficient numbers to be damaging only occur in the presence of this infection,” lead author Dr. Alejandra Pera, a researcher at BSMS, said in a press release. They found that certain tissue types, which are determined genetically, make individuals more susceptible to large numbers of these cells. With this discovery researchers believe heart disease can be controlled by treating the virus.

Videos: stunning AI show how it will kill 90 % VACCINE DAMAGED HEALTHCARE WORKER TO UNVACCINATED FRIENDS: “I COMMEND YOU: I WISH I WERE ONE OF YOU” FATHER OF CHILD WITH MYOCARDITIS RECORDS PHARMACIST ADMIT PARENTS' AREN'T WARNED ABOUT SIDE EFFECTS WHISTLEBLOWER NURSE IN WASHINGTON DESCRIBES VACCINE INJURIES FROM EMPLOYMENT MANDATE Higher vitamin C levels associated with lower mortality risk during 16-year period Chinese Academy of Medical Sciences, August 20 2022 A study reported in the Journal of Epidemiology and Community Health has uncovered an association between higher plasma vitamin C levels and a lower risk of mortality during more than 16 years of follow-up. The study included 473 men and 475 women between the ages of 53 and 84. Among subjects whose plasma vitamin C concentrations were among the top 25%, the adjusted risk of dying from any cause during follow-up was 25% lower than the risk experienced by subjects whose vitamin C levels were among the lowest quarter. Those whose plasma vitamin C levels were among the highest 25% had an adjusted risk of dying from cancer or stroke that was 28% lower and a risk of dying from heart disease that was 35% lower than subjects whose levels were lowest. When subjects with low vitamin C levels (defined as 28 micromoles per liter or below) and normal levels (greater than 28 micromoles per liter) were compared, a normal level was associated with a 23% lower risk of premature mortality and a 38% lower risk of dying from heart disease, in comparison with low levels. As a possible reason for their findings, Shao-Ming Wang and colleagues note that oxidative stress is lowered by vitamin C. Oxidative stress can promote endothelial dysfunction that underlies heart disease by increasing inflammation and lipid peroxidation and decreasing nitric oxide availability. Oxidative stress also causes DNA damage associated with cancer. Pomegranate-cocoa blend helps improve aging men's symptoms Shetty Hospital (India), August 19 2022. A study published in the International Journal of Medical Science found benefits for supplementing with a combination of extracts of Punica granatum (pomegranate) fruit rind and Theobroma cocoa seed extracts in middle-aged men. Previous research that investigated the effects of a blend of extracts of pomegranate fruit rind and cocoa seed in young men resulted in increases in serum and free testosterone levels as well as muscle strength and size. The current study included 120 men between the ages of 36 to 55 years who received 200 mg or 400 mg of pomegranate-cocoa extract or a placebo for 8 weeks. All participants were assigned to a program consisting of 30 minutes of walking per day for 5 days per week. At the end of the 7-week period, both doses of pomegranate-cocoa extracts were associated with significant improvement in aging males' symptom scores, free and total testosterone levels, strength and perceived stress compared to the beginning of the study and to the placebo group. The authors concluded that pomegranate-cocoa “is a well-tolerated, safe, and effective nutraceutical blend that boosts sexual function, testosterone level, and psychological and general well-being in aging males.” Placebo effect demonstrates healing power of the mind Harvard Medical School, August 13, 2022 Experts at Harvard Medical School advocate that the placebo effect be received with more positivity, rather than viewed as a deceptive or inaccurate measure designed to test health. They conclude that the power of thought can be extremely effective in helping people heal, focusing on physiological changes that have been linked to the placebo effect. The placebo effect involves someone being given medicine that is actually typically nothing more than a sugar pill which does not contain active ingredients. Many times, patients receiving a placebo who are in need of healing a certain condition report feeling significantly better, if not altogether healed. The experts at Harvard explain that improvements may take place because of the anticipated response that a person expects when given medication. The university's literature says that there is “evidence that some of the placebo effect is a favorable reaction to care and attention from people who patients believe can help ease their suffering and distress.” It goes on to say that the placebo effect “may be an integral part of good medical care and an ally that should be embraced by doctors and patients alike.” This paves the way for potential changes in how health is handled and, furthermore, reinforces the strength of the human mind to bring about healing and desired outcomes, health or otherwise. Awake within a dream: Lucid dreamers show greater insight in waking life University of Lincoln (UK), August 12, 2022 People who are aware they are asleep when they are dreaming have better than average problem-solving abilities, new research has discovered. Experts from the University of Lincoln, UK, say that those who experience ‘lucid dreaming' — a phenomena where someone who is asleep can recognise that they are dreaming — can solve problems in the waking world better than those who remain unaware of the dream until they wake up. It is thought some people are able to do this because of a higher level of insight, meaning their brains detect they are in a dream because events would not make sense otherwise. This cognitive ability translates to the waking world when it comes to finding the solution to a problem by spotting hidden connections or inconsistencies, researchers say. The research by Dr Patrick Bourke, Senior Lecturer at the Lincoln School of Psychology, is the first empirical study demonstrating the relationship between lucid dreaming and insight. The study examined 68 participants aged between 18 and 25 who had experienced different levels of lucid dreaming, from never to several times a month. They were asked to solve 30 problems designed to test insight. Each problem consisted of three words and a solution word. Results showed that frequent lucid dreamers solved 25 per cent more of the insight problems than the non-lucid dreamers. The role of dietary coconut for the prevention and treatment of Alzheimer's disease Curtin University (Australia), August 12, 2022 According to news reporting originating in Bentley, Australia, research stated, “Coconut oil, derived from the coconut fruit, has been recognised historically as containing high levels of saturated fat; however, closer scrutiny suggests that coconut should be regarded more favourably.” The news reporters obtained a quote from the research from Curtin University, “Unlike most other dietary fats that are high in long-chain fatty acids, coconut oil comprises medium-chain fatty acids (MCFA). MCFA are unique in that they are easily absorbed and metabolised by the liver, and can be converted to ketones. Ketone bodies are an important alternative energy source in the brain, and may be beneficial to people developing or already with memory impairment, as in Alzheimer's disease (AD). Coconut is classified as a highly nutritious ‘functional food'. It is rich in dietary fibre, vitamins and minerals; however, notably, evidence is mounting to support the concept that coconut may be beneficial in the treatment of obesity, dyslipidaemia, elevated LDL, insulin resistance and hypertension – these are the risk factors for CVD and type 2 diabetes, and also for AD. In addition, phenolic compounds and hormones (cytokinins) found in coconut may assist in preventing the aggregation of amyloid-beta peptide, potentially inhibiting a key step in the pathogenesis of AD.” According to the news reporters, the research concluded: “The purpose of the present review was to explore the literature related to coconut, outlining the known mechanistic physiology, and to discuss the potential role of coconut supplementation as a therapeutic option in the prevention and management of AD.” Cold sores virus, cardiovascular damage linked in study Brighton and Sussex Medical School, August 14, 2022 A herpes virus similar to the one that causes cold sores has been linked to immune cells that can damage cardiovascular tissue, according to a study. Researchers at the Brighton and Sussex Medical School in England found that a relevant number of a specific type of immune cells arise when infection with cytomegalovirus is present. Their findings were published in the journal Theranostics. The virus, which is frequently associated with the salivary glands, has been considered harmless because the immune system usually controls it. But the CD28null CD4 T-cells have been known to be involved in damaging the arteries around the heart. Cytomegalovirus infection increases the risk of cardiovascular death by over 20 percent, according to a study published last year in the Journal of the American Heart Association, but the effect wasn't identified. One theory was they were a natural consequence of aging. “While we had previously been aware of a link between these immune cells and cardiovascular damage, this study is the first to show that sufficient numbers to be damaging only occur in the presence of this infection,” lead author Dr. Alejandra Pera, a researcher at BSMS, said in a press release. They found that certain tissue types, which are determined genetically, make individuals more susceptible to large numbers of these cells. With this discovery researchers believe heart disease can be controlled by treating the virus.

Our guest this week is Shayne Gaffney of Windham, NH, a cycling & running coach, a licensed physical therapy assistant, and father of two including a daughter with CytoMegaloVirus, or CMV.Shayne and his wife, Megan, have been married for 8 years and are the proud parents of two children: Finn (5) and Grace (3), who was diagnosed with CytoMegaloVirus or CMV, a common virus, but when a baby is born with congenital CMV infection, it can result in several long-term health problems. We learn about the Gaffney family journey, their advocacy for those impacted by CMV and the role Easter Seals & the CMV Foundation has played in their lives. That's all on this episode of the SFN Dad To Dad Podcast. Email – Gaffney.shayne@gmail.com Phone – (978) 604-5543Website - http://www.gccoaching.fit/LinkedIn – https://www.linkedin.com/in/shayne-gaffney-19011914a/ Easter Seals of New Hampshire - https://www.easterseals.com/nh/ National CMV Foundation - https://www.nationalcmv.org Website – https://www.nowiknowcmv.com Special Fathers Network - SFN is a dad to dad mentoring program for fathers raising children with special needs. Many of the 500+ SFN Mentor Fathers, who are raising kids with special needs, have said: "I wish there was something like this when we first received our child's diagnosis. I felt so isolated. There was no one within my family, at work, at church or within my friend group who understood or could relate to what I was going through."SFN Mentor Fathers share their experiences with younger dads closer to the beginning of their journey raising a child with the same or similar special needs. The SFN Mentor Fathers do NOT offer legal or medical advice, that is what lawyers and doctors do. They simply share their experiences and how they have made the most of challenging situations. Special Fathers Network: https://21stcenturydads.org/about-the-special-fathers-network/Check out the 21CD YouTube Channel with dozens of videos on topics relevant to dads raising children with special needs - https://www.youtube.com/channel/UCzDFCvQimWNEb158ll6Q4cA Please support the SFN. Click here to donate: https://21stcenturydads.org/donate/

Listen as Dr. Megan Pesch shares her journey to becoming a parent advocate and a researcher in Cytomegalovirus (also called CMV). Dr. Pesch is an Assistant Professor of Developmental and Behavioral Pediatrics at the University of Michigan where she is the Director of the Congenital CMV Developmental Follow-up Clinic. Dr. Pesch completed her medical school training, residency, and fellowship at the University of Michigan. She is board certified in Developmental and Behavioral Pediatrics and serves as the President-elect of the National CMV Foundation. Dr. Pesch's youngest daughter has a profound bilateral sensorineural hearing loss from congenital CMV and this led to her involvement in national advocacy efforts to ensure that all newborns receive CMV screening.  Dr. Pesch's clinical interests include the early diagnosis and treatment of congenital CMV using a multidisciplinary approach with a focus on family care and support, while her research focuses on healthcare provider practices around congenital CMV diagnosis and management and understanding the relationship between autism and CMV.   The month of June is CMV awareness month. Please visit the National CMV foundation to learn more about advocacy efforts in CMV in your area and how you can support NBS for CMV.   Learn more about Dr. Megan Pesch and her advocacy effort on newborn screening for CMV: https://ihpi.umich.edu/our-experts/pesch https://www.nationalcmv.org   Podcast Interview Question with Dr. Megan Pesch. You are currently an Assistant Professor of Developmental and Behavioral Pediatrics and the Director of the Congenital CMV Developmental Follow-up Clinic at the University of Michigan. Can you tell our listeners more about CMV and how it impacts mothers, their babies and families? (perhaps, talk about the differences between prenatal CMV and neonatal congenital CMV)? You are a clinician and a researcher, and lead efforts in the Pesch Lab at Michigan Medicine at the University of Michigan! One of your projects brings together a multidisciplinary group of health care providers to refer infants who fail their newborn hearing screen for congenital cytomegalovirus testing. Tell us more about this important project and explain how you got involved in newborn screening research? Currently, there is no standard of care or routine screening for newborns for congenital cytomegalovirus at birth. What can parents do if they suspect their baby has CMV? (perhaps discuss the Alethia CMV Assay Test System) What is hearing targeted early cytomegalovirus (HT-CMV) screening? One of your current studies seeks to understand the possible connection between exposure to CMV during pregnancy and the later risk of autism. Can you tell us more about this effort? What are you hoping to learn? What is the biological pathway? You are also the President-elect of the National CMV Foundation. What are some of the current activities or programs that people can get involved in your advocacy efforts? What are the recent advocacy efforts to support newborn screening for CMV? Is it currently being reviewed to be added to the RUSP? Are you involved in training the next generation of pediatricians, and what do you tell them about newborn screening research? You are busy as a clinician, researcher, advocate, and parent. Do you have any stories of inspiration that keep you going? What does NBS research mean to you? To learn how NBSTRN can help your research in newborn screening, visit www.nbstrn.org  

Local mom and public health professional Cara Gluck joins us to recognize June as Cytomegalovirus (CMV) Awareness Month. This virus affects 1 in 200 babies born in the United States and can have long-term, significant developmental impacts on a baby if a mom contracts the virus while pregnant. Cara joins us to share her family's journey with CMV, simple steps pregnant moms can take to reduce their risk and what all parents-to-be need to know about the virus.

In this week's episode, Curious Wanderer and Master of Ceremonies reach the Oculary of Lies, where Curious Wanderer is allowed to see three visions of his future. One is a lie, one is a half-truth, and one is the truth. SnackPax introduces the show and provides an exciting journey through opportunistic CMV and a brief and exciting never before seen case of congenital cytomegalovirus.

Snack Pax is back with another episode of Epi After Dark. This week as we progress through the House of Opportunists Pax examines the most important defining features of the early AIDS Crisis through examination and retrospective analysis of the June 5, 1981, and July 3, 1981, MMWR issues that alerted medical professionals to the crisis. The Master of Ceremonies and Curious Wanderer manage to escape the Inverted Pole only to discover there is more than meets the eye when it comes to the Oculary of Lies. Check back next week for the next episode where we cover Cytomegalovirus.

In this episode from the series “Key Decisions in HIV Care,” Cristina Mussini, MD, and William R. Short, MD, MPH, AAHIVS, discuss important considerations for ART with opportunistic infections, including: When to start ART with pneumocystis pneumonia including discussion of the ACTG 5164 study of immediate vs delayed ART with opportunistic infectionsEACS, DHHS, and IAS-USA guideline recommendations for starting ART in the setting of most opportunistic infectionsConsiderations for the administration of ART to patients who are unable to swallow or critically ill and intubatedTreatment of Kaposi sarcoma and considerations for starting ART to avoid drug–drug interactions with Kaposi sarcoma treatmentConsiderations for starting ART with cytomegalovirus and the risk for IRIS from cytomegalovirusDiscussion of treatment of cytomegalovirus and overlapping toxicities between its treatment and ARTWhen to start ART with cryptococcal meningitis and the data to support delayed treatment initiation with this particular opportunistic infectionEACS, DHHS, and IAS-USA guideline recommendations for starting ART in the setting of cryptococcal meningitis specificallyTreatment of cryptococcal meningitis and managing drug–drug interactions between ART and antifungal therapyPresenters:Cristina Mussini, MDHead of Department of Infectious Diseases and Tropical MedicineFull Professor of Infectious DiseasesInfectious Diseases Clinics University HospitalUniversity of Modena and Reggio EmiliaReggio Emilia, Italy William R. Short, MD, MPH, AAHIVSAssociate Professor of MedicineDivision of Infectious DiseasesDepartment of MedicinePerelman School of Medicine at the University of PennsylvaniaPhiladelphia, Pennsylvania Content based on an online CME program supported by educational grants from Gilead Sciences, Inc.; Janssen Therapeutics, Division of Janssen Products, LP; and ViiV Healthcare.Follow along with the slides at:https://bit.ly/3uktrm1Link to full program:https://bit.ly/3q2DlGd

What's the cause of fetal growth restriction? How can you prevent it? In this episode of True Birth, we will talk about fetal growth restriction/FGR previously termed IUGR or Inner Uterine Growth Restriction.       What is FGR? [1:36] It is when the baby falls below the 10th percentile for weight. 10% of babies will be below the 10th percentile, by definition. Hence, 10% of babies will be classified as fetal growth restricted. It's important for you to know that because 10% of babies are not in a pathological situation. They're not in a bad situation. They're not in a situation where they're not growing.    [2:35] It's important to consider each woman and her partner uniquely in pregnancy.  A women that is  5'9 with women and a woman that is 5 feet tall will have different size expectations and patterns when it comes to pregnancy.    Possible reasons that the baby is small [4:17] The number one reason that a baby could be on the smaller side is that the mother is small and the father of the baby is maybe not the tallest guy. We use the term FGR/Fetal Growth Restriction when they're in utero, but once they're delivered, we call them SGA/Small for Gestational Age.    [5:06] When you find the baby's not growing well, this will generally be after 20 weeks Babies are generally the same size until 20 weeks.    [6:08] Another reason the baby is small is that it's supposed to be small and there's nothing wrong. The number two reason is placental perfusion. It has a problem with the baby getting enough blood flow and nutrients. It is just not getting enough of what it needs to grow well. And there are many reasons why the placenta won't function. So when you see a small baby, especially in the third trimester after 27 weeks, 30 weeks, start thinking, "Oh, how are her blood pressures? She's spilling protein. Is there something going on with this patient that's pointing me towards preeclampsia?"   [8:07] TORCH is an acronym that stands for toxoplasmosis, rubella cytomegalovirus, herpes simplex, and HIV. Cytomegalovirus is a virus that's very common in the population. Most people have been exposed to cytomegalovirus. T  Ultrasound tools [12:09] To understand Dopplers without getting into the physics of what the Doppler effect is, you can take your transducer, you could put it over the cord, and you can turn on the Doppler and you could see the blood flow through the cord.   [13:48] When you look at a Doppler, and you see the blood flowing the way it should, before the next heartbeat, you measure how fast it's going right before the next heartbeat.   [15:14] When you talk about fetal growth restriction, you can't just talk about the baby's size because there's only one piece of it. The other piece is what is the placenta telling you? What are the Dopplers telling you?    [15:34] Biometry is when you measure the femur and the abdomen and measure the head to get the size and weight of the baby and estimated fetal weight.    Guidelines about how to approach Fetal Growth Restriction [18:12] If you're below the third percentile, even if everything else is okay, that's the baby you got to deliver at 37 weeks. You can't just sit around and look at that baby for 37 weeks get the baby out. If your baby is above the third percentile and the Dopplers are elevated but not absent, get the baby up. And if there's no flow, the blood stops, that's even more concerning. If you see the reverse flow, you're dealing with a much more ominous situation and you don't want to go past 32 weeks. If you don't think the baby's doing well, you might have to come out even earlier.   Biophysical profile [22:09] One of the things that some patients might have to consider in other practices is that they would need to start having biophysical profiles done. A biophysical profile is when you're checking for a series of four different things and looking to ensure that the baby is reassuring overall. What is the baby's movement? What is fetal breathing, which is an exercise the baby does to inhale and exhale fluid? What is his tone? Is the baby flex or the floppy? Or if you feel the baby's not moving, these are things that you have to consider.   [23:51] One of the things you're looking for when talking about growth restriction is you want to see how the baby is handling the uterine environment? How's the baby doing on the inside? These tests will wish to you to identify a baby that's not doing well or not getting enough blood flow. You need to know if you can wait on it and let the baby stay inside, or is it time to get the baby out? Because then the baby will do better outside of the womb.    Recommendations [24:20] The recommendation is that if you recognize growth restriction, you should at least be monitoring weekly, that might be nonstress tests, or that might be a biophysical every week. And if you have a severe growth that restricts a baby under the third percentile or abnormal Dopplers or accident, then twice a week. If you have reversed outside flow, put those patients in the hospital because they need to be monitored around the clock and you got to pull the baby out before it's too late.     [29:08] The most reliable and consistent way to assess blood flow to the baby is the umbilical artery. Look at the ductus phimosis. When the umbilical cord hits the baby's belly button, a big part of the vein goes up into the heart carrying the birth at heart, and you can see if there's resistance, or even at the umbilical vein.   Here is the photo that we have permission to share.    Visit https://www.truebirthpodcast.com/ to listen more episodes! Maternal Resources Social Facebook: https://www.facebook.com/maternalresourceshackensack |nstagram: @maternalresources Subscribe to the podcast on Apple Podcasts, Spotify, Google Podcasts, & Stitcher and leave a review!