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Dr. Deb Muth 00:00:09 Hi there, how are you? Bob Miller 00:00:10 Excellent! Pedaling as fast as humanly possible, but doing okay. Dr. Deb Muth 00:00:14 Good, good. Well, I’m looking forward to our conversation today. This should be amazing. Bob Miller 00:00:20 Yeah, it should be a lot of fun. Dr. Deb Muth 00:00:22 Yeah, anything that’s off-limits for you in, our conversation? Bob Miller 00:00:28 No. Dr. Deb Muth 00:00:29 Okay, anything you want me to make sure we cover for you? Bob Miller 00:00:33 Well, I mean, is it okay if we put a little plug-in for our software? Dr. Deb Muth 00:00:35 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:38 Hey, can we… can we do a screen share? Yes, we can. Yeah, because I want to show you some maps, and… Dr. Deb Muth 00:00:43 Okay. Things like that, yeah, so… Perfect. So just let me know when you want to do screen share. Bob Miller 00:00:48 Okay. Dr. Deb Muth 00:00:49 And yeah, feel free to plug your software wherever you want to. Bob Miller 00:00:53 Okay, well, good. Let me pull up a, a slide for that, and give me one second, I just want to shut the door to my office to get the noise down. Dr. Deb Muth 00:01:01 No worries. Bob Miller 00:01:16 And, how should I refer to you? Dr. Debb? Dr. Muth, what do you like? Dr. Deb Muth 00:01:18 Dr. Deb is great, or Deb, either way, I’m pretty informal, so… Bob Miller 00:01:22 Yeah, and… Bob is fine for me. Okay. Yeah. Yeah, there you go. Why people feel like they need this, son. Special name, it’s like, seriously. Dr. Deb Muth 00:01:33 Right? I agree. Bob Miller 00:01:35 When I work with my clients, it’s like, Dr. Millison, just, just bop, just, just bop. Dr. Deb Muth 00:01:41 Yep, that’s how I am, too. Just call me Deb, it’s good. Dr. Deb Muth 00:01:44 They feel a little awkward with that, you know? They’re not used to that, but… Bob Miller 00:01:48 Alright. And you’re a naturopath, medical doctor. Dr. Deb Muth 00:01:52 A nastropathic doctor and a nurse practitioner. Oh, nice. Yeah, so I got the best of both worlds, right? Bob Miller 00:01:58 Yeah, damn. Okay. Alright, so here we go… There we go. Alright, so I got that ready, and then I will do a, I will do a screen share. I think you’re gonna really, appreciate what we’ve come up with. We’ve come up with the concept of, Cellular CPR. Dr. Deb Muth 00:02:23 Oh, nice! Bob Miller 00:02:24 And that is, construct the cell membrane, Protect the cell membrane. And restore it if it’s damaged. Dr. Deb Muth 00:02:32 Love that. Bob Miller 00:02:34 I love that. Yeah, so that’s what we’re focusing on, and then how, You know, we want to get to the point that, you know, most people think of genetics, they think of, like, 23andMe or Ancestry. Dr. Deb Muth 00:02:44 Yeah. Bob Miller 00:02:45 And then you have the professional geneticists who are looking at, you know, odd things that could create a disease. We’re looking at functional genomics. Dr. Deb Muth 00:02:54 Which is so much better. Bob Miller 00:02:56 Yeah. Are you familiar with what we do here, or… Dr. Deb Muth 00:02:58 A little bit, a little bit. So, it’ll be new to me, too, so I’m excited. Bob Miller 00:03:03 And how much time do we have? Dr. Deb Muth 00:03:04 We have an hour, give or take a little bit on either side. Do you have a hard stop anywhere? Bob Miller 00:03:10 No, no, I put a, I moved my clients around, and I don’t have anybody till, 3.30, so we’re good. Okay. Dr. Deb Muth 00:03:16 Perfect. Alright. Bob Miller 00:03:18 It’s like we’re getting started early as well, so… Dr. Deb Muth 00:03:19 Yeah, we’re getting started a little bit early, so that’s good. Bob Miller 00:03:22 Yeah, I just got my office cleaned up, so… Dr. Deb Muth 00:03:23 Okay, good. All right, are you all set to get started? Bob Miller 00:03:28 I’m good to go, my friend. Dr. Deb Muth 00:03:29 I’m gonna just record a little intro and a little bit of a, hook for people, and then we’ll get started. I’ll ask you to kind of tell us a little bit about yourself, and then we’ll just take this conversation wherever it’s supposed to go. Bob Miller 00:03:39 Okay, you got it. Dr. Deb Muth 00:03:40 Alright, sounds good. So what if the reason you’re not healing isn’t your diet, your supplements, or your labs, but it’s actually your genes? Dr. Bob Miller is uncovering how genetic variants, when combined with modern toxins, explain why some of us stay sick no matter what we try. Today, we’re talking genetic pathways, detox blocks, and the new science every wellness warrior needs to know. Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, exploring cutting-edge regenerative medicine, and empower you to heal from the inside out. I’m Dr. Deb, your medical detective, and today, our guest, Dr. Bob Miller, is a true pioneer in functional genomics. He’s a board-certified traditional naturopath and the founder of Neutrogenetic Research Institute. And he’s the leading groundbreaking research on how genetic variants influence chronic illness, inflammation, and detoxification. His work has been recognized on international stages, uncovering links between genetic expression and conditions like Lyme disease, mast cell activation, or MCAS, and mitochondrial dysfunction. I’m so excited to talk to Dr. Bob today. He is gonna reveal some things that even I don’t know about, so I’m excited to learn alongside of you guys. So… Dr. Bob, let’s get started. Tell us a little bit about yourself, and kind of how you got on this journey. Bob Miller 00:05:04 Well, that’s, that’s interesting. I was sort of like a mid-career coming to the natural health field, because in my early 30s, I found myself with a severe case of ulcerative colitis. Bob Miller 00:05:15 And I was in the hospital for 21 days. probably within hours of death, pleading to death. And they told me I’ve got one option, and that is cut out the colon and wear a bag. Didn’t sound like a lot of fun. Dr. Deb Muth 00:05:27 Not an option I would want. Bob Miller 00:05:29 So, you know, the medical folks wasn’t real happy with me, but I said, yeah, I’d like to explore some alternative things.Never thinking that I’d get into this field, and then I just, you know, worked with some herbalists and things that I found absolutely fascinating. So, that’s how I got into this around 30 years ago. And, haven’t looked back since, and just having a… having a blast as we now move into how our genetics impacts things. So, that’s what we’re gonna… that’s what we’re gonna talk about today. Dr. Deb Muth 00:05:58 I’m excited to talk about this genetic thing. When you started over 30 years ago, what kind of patience and problems first inspired you to dig deeper into that root cause healing and kind of get into the genetic piece of it? Bob Miller 00:06:10 Sure. Well, you know, as a… now, I’m in a part of the country called Lancaster County, Pennsylvania, where there’s a lot of Amish and Mennonite, and they gravitate towards these things.So, this is their first thing to do, and that doesn’t work, then they’ll go other routes. So, you know, back then, we just saw typical, you know, a little tired, constipation. You know, a little bit of fatigue, arthritis, those kind of things. But things have changed dramatically over the years, as people are now getting more chronically sick. You know, it’s worse than it’s ever been. And what we’re finding is the, the culprits Primarily is mold exposure and Lyme disease. When people get those two together, they’re just… it’s an inflammatory cascade that nobody can seem to unravel. So that’s where we spend a lot of our time. And we’re also spending a lot of time looking at mental health, like ADD, ADHD. And, we give… this year I’ll be speaking at three autism conferences. And we can dig into that a little bit as to why we think we’re seeing such a dramatic increase. And aside from autism, that used to be 1 out of 1,000, now it’s 1 out of 33, or 23. You know, we’re also seeing dramatic increases in ADD, ADHD. People are stressed out. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. Dr. Deb Muth 00:07:37 This should be a fun visit. We can cover lots of topics. I am so excited. So, you founded Nutri Genetic Research Institute in 2015. What did you hope to accomplish, and what kind of surprised you in your findings so far about that? Bob Miller 00:07:51 Well, you know, let’s back up at what, you know, genetics is used for. Everybody’s familiar with 23andMe and Ancestry that, you know, tells you where your ancestors came from. Then you have your professional geneticists. I mean, these are people with a degree in genetics. And they’ll look for, you know, very odd sort of things that are prone to relate to a disease. So there are disease-related genetics. Well, in functional, we don’t look at either of those. We look at For example, how you’re breaking down your fats and utilizing them. How you’re recycling your glutathione. How you might be handling your iron. And none of those are disease-causing on their own.And none of those are disease-causing on their own. But when they pile up on you, and then combine that with environmental factors, that’s when things start to go south on us. So, that’s what we’re doing, we’re looking at patterns. And our first foray into this was, we did studies on Lyme disease. And our first foray into this was, we did studies on Lyme disease. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. Others have a little more struggle, and then others are struggling terribly for years. So there’s an old adage of genetics loads the gun, environment pulls the trigger. Dr. Deb Muth 00:09:14 Yeah, that is so true, and I think when we’re talking about Lyme and mold and things like that, we forget sometimes that our genetics can predispose us to be more sensitive to those things, and if we have genetic pathways where we don’t clear things properly, it’s harder for us to get them out of the body. And then you add on that whole rain barrel effect that we’ve always used as a functional medicine term, right? If the barrel’s half full, you’re okay. If it’s full, and now it’s spilling over, it’s a bigger problem. Have you guys found, too, that some of these environmental things actually are changing the genetics of people, or how they’re processing their own genetics? Bob Miller 00:09:53 Well, let’s go back to, Genetics 101. But we’ll go back a little bit further. So, what an interesting mechanism, what a miracle the body is. Bob Miller 00:10:03 Fats, carbohydrates, proteins, drink water, breathe air, expose the sunlight, and somehow everything gets made. I mean, when you just step back and think about that, it’s like, It’s pretty darn amazing. Dr. Deb Muth 00:10:15 I always tell women, you know, the fact that we get pregnant and we have healthy pregnancies and births is a miracle, because if we had to try to control that, that wouldn’t work so well. Bob Miller 00:10:25 Right. Well, that’s another miracle. These microscopic sperm and egg, human being, 9 months later, it’s like. But even inside of us. We are making our hair, our skin, our nails, our blood vessels, our ATP, our energy, it’s all being created. Well, that gets created by enzymes. So, enzymes take one substance, combine it with something else, and make something new. Then another enzyme comes along and does the same thing. Your DNA is the instructions on how to make the enzymes. So, when we are conceived. If it’s a, if it’s a female, of course, it’s the XX, the two chromosomes. You know, we’ve… everybody’s seen those… the genetics that… Listed pair. So, if it’s a female, the father donated the X enzyme. And the mother has no choice but to give the eggs, so that’s female. If the father donates the Y, you have a male that’s in chromosome number 1. Then 2 through 23 is the rest of the instructions on how to make enzymes. So, what can happen? We can get what are called SNPs, single nucleotide polymorphisms. And SNPs just mean that the instructions to make the enzyme’s not quite as good. So, if one parent gives a SNP on the making of an enzyme, The enzyme’s fine. It works. But, general rule of thumb, It may only work at 70-80% of efficiency. Now, a good analogy is think of an 8-cylinder and a 6-cylinder car. If parents give you good information, that’s like having an 8-cylinder car. If one parent gives you that snip, it’s like having a 6-cylinder car. Now, is a 6-cylinder car a fine car? Sure. It’ll get you from point A to point B, but it’s just going to have the power of an 8-cylinder. Then if both parents give you a SNP on the same enzyme, it may be 30-40%, and that’s like having a 4-cylinder car. Sits in the driveway, looks the same, puts gas in it, everything. But if you’ve got a 4-cylinder car. Probably not a good idea to go cross-country pulling a trailer behind you up and down mountains. Dr. Deb Muth 00:12:29 This is true. Bob Miller 00:12:32 So… We can get an 8-cylinder, 6-cylinder, or 4-cylinder enzyme. Now, if it’s not under a lot of stress, if that 4-cylinder car is just taking you to the bank and the grocery store. It’s just as good as an 8-cylinder car. But if you gotta pull that trailer, and there’s a lot of stress on it, being mountains, it’s gonna struggle. Now, there’s one other little caveat to this, and that is some genetic mutations are gain-of-function. They actually work faster. Now, we have enzymes that do all kinds of things. We have enzymes that make and recycle our antioxidants, but we also have enzymes that make inflammation. No, that’s a good thing, because if we get a virus or bacteria, if you didn’t make inflammation to kill it, well, we’d all die of infection. So, you know, we tend to think of free radicals as bad, antioxidants as good. They both play an important role. But interestingly, some of the major enzymes that make inflammation, they can be overactive. They can be turbocharged. And when they’re stimulated by environmental toxins, they overreact. Bob Miller 00:13:40 And therein lies the problem. When they overreact, we have a problem. Bob Miller 00:13:46 So, if we have genes that overreact when stimulated. And then the enzymes that take care of inflammation are underactive. Then you’re gonna be more inflamed. You know, the majority of people that, you know, come for functional medicine Or naturopathic help, or… Inflammation that they can’t seem to get under control. Dr. Deb Muth 00:14:06 Right. Bob Miller 00:14:07 And we will be, you know, during this hour, we’re going to look at some of the pathways that make that happen. So, what we can do then, we can’t change our genetics. When you’re conceived, that’s the hand you’re dealt. When your life would be over, if someone would take some tissue and measure, it’d be exactly the same as conception. Does it change. Bob Miller 00:14:28 The enzyme’s ability to do its job may be compromised. Because remember I said there’s a, the enzyme takes a cofactor. So an enzyme takes substance A, cofactor, make substance B. Well, if that cofactor’s not there, the enzyme’s not going to work either. So, you could have an 8-cylinder car, and if there’s no gas in it, it’s not going anywhere. So… It’s the strength of the enzyme, it’s the cofactor to do the A to B conversion. And that’s what we’re going to get into. So, many people say, well, where did these SNPs come from? Nobody knows for sure. Sometimes they’re what’s just called de novo, when the sperm and egg go together, the instructions get mixed up a little bit. We do believe a lot of it came from a long time ago, when we were almost wiped out by sexually transmitted diseases. And those STDs were altering the genes when the conception, in other words, when the sperm went into the egg, the STDs were interfering. And causing the problem, so… I often joke, if you want to blame somebody. Blame your great-great-great-great-great-great-great-grandparents for, being a bit promiscuous, so… Dr. Deb Muth 00:15:31 Yeah, for being… having a little too much fun, right? Bob Miller 00:15:35 So, we don’t know for sure, but, you know, there are some that, But most of the SNPs that we get inherit from our parents. So, if you look at a child. And you look at the SNPs. 99.9% of the time, it came from one of the parents. Dr. Deb Muth 00:15:50 In identical twins, do they have the exact same identical makeup? Bob Miller 00:15:54 Yep, Dr. Deb Muth 00:15:56 But not in fraternal twins, correct? Bob Miller 00:15:59 No, no, those could be different, Jeff. Dr. Deb Muth 00:16:00 It could be different because they have different sacs, they’re not sharing that same genetic makeup. Bob Miller 00:16:04 Yeah, so keep in mind, both your mother and your father have, you know, the two And so you get one from one parent, one from another. Dr. Deb Muth 00:16:13 So… Bob Miller 00:16:14 Interesting situation. I had, 3, 3 boys. And, we were looking at an enzyme related to breaking down oxalates. Now, the mother and father each had one SNP, and that’s called heterozygous. Three boys, and they all come together, they’re Amish boys, they’re a lot of fun. And I looked at their genomes, and the one boy didn’t have any SNPs at all. And one had won. And the other one had two. Dr. Deb Muth 00:16:41 Interesting. Bob Miller 00:16:42 So, we don’t quite know how these things get handed off, but with the parents each having one, you could have a child with none, one, or two. So, the one, his ability to break down oxalates, which is fine. The other one was slightly impaired, and the other one was dramatically impaired. So, you can have 3 children, and it all depends what the parents have. Now, if a parent has a homozygous, or 2 copies. And the other parent has nothing. Every child will have one. Okay. If both parents are homozygous, that they both have two, Every child will have two. Dr. Deb Muth 00:17:19 too. Bob Miller 00:17:20 Yes, so that’s the way it works, but, you know, but it’s somewhat rare that both parents are homozygous on an enzyme, but it can happen. Dr. Deb Muth 00:17:27 Do we think that infections today, like Lyme disease or mold exposure, things like that, if the parent, the woman, primarily, I’m thinking, is pregnant, and she actively has these infections. Can those infections affect the genetics, kind of like a past sexual transmission did where we thought back in the day? Bob Miller 00:17:47 Yeah, I… I mean, I’m not that much of a geneticist to answer that for sure, but my thought would be no, that at conception, the pattern’s made. Dr. Deb Muth 00:17:55 Okay. And then that’s… that’s the hand you’re dealt. Bob Miller 00:17:58 Yeah. So, I tell people we have good news and bad news. The good news is we can compensate for the weakness. The bad news is we can compensate for the weakness. Dr. Deb Muth 00:18:09 That is so very true. Bob Miller 00:18:11 Yeah, we can’t, because I often get asked, so we’ll do some things now, and we’ll check my genes again, and they’ll be better. It’s like, nope. Dr. Deb Muth 00:18:18 Oh, – – Bob Miller 00:18:19 You gotta play the hands you’re dealt, so… Dr. Deb Muth 00:18:21 That’s right. Bob Miller 00:18:22 You can test your genetics… if you’re looking at the same enzyme, you can test it every year. It’s not gonna change. It’s like the blueprint. Dr. Deb Muth 00:18:30 It’s good and bad, right? It’s the one test you only have to do once in your lifetime. Bob Miller 00:18:34 No, unless, you know, like, our. Dr. Deb Muth 00:18:36 All the time. Bob Miller 00:18:37 Yeah, now our test looks at, called the Functional Genomic Analysis Test of your genomic Resource. We look at 220,000 steps. Dr. Deb Muth 00:18:46 Wow, that’s a lot. Bob Miller 00:18:47 That’s not all of them. Dr. Deb Muth 00:18:49 Right. Bob Miller 00:18:50 So, maybe in the next year, we’re gonna come out with our third version of the chip. And then, if someone wants to get those new things that weren’t on it, they’d have to repeat. But whatever we measured is gonna stay the same. Dr. Deb Muth 00:19:03 That’s a lot of SNPs to look at. Bob Miller 00:19:05 Keeps us busy. Dr. Deb Muth 00:19:06 But there’s still, but there’s still SNPs that we. Bob Miller 00:19:09 That we’d like to have that we don’t have, so… Bob Miller 00:19:11 We started out with version 1 on our genetic test, then we worked with version 2, and we’re already compiling a list of what version 3 would look like. So if somebody has our version 2, And we’re saying, you know what, it’d be nice if we could see these, well, then you’d repeat, but it won’t change what you already know, so… Dr. Deb Muth 00:19:29 Got it, got it. So, when you started out, and you started looking at the research of Lyme disease and chronic infections, which detox pathways are most important for people who struggle with those conditions? Bob Miller 00:19:43 Okay. You know what might make sense as we do a screen share, and I’ll actually show you the pathway. Does that make sense? Bob Miller 00:19:48 Alright, so… let’s see if I… let me just press the share… Dr. Deb Muth 00:19:52 Yep, you should just be able to press share. Bob Miller 00:19:54 And… number 2. Okay. Are we seeing the screen there? Bob Miller 00:20:01 Okay. Dr. Deb Muth 00:20:02 So, this is a map that we made. Bob Miller 00:20:05 And by the way, this is not… All-inclusive of all the things we look at, but we believe this is a core issue. So, where we’re going to start here, there’s something called the microglia. And the microglia are glial cells. They’re in the brain and the central nervous system. And they’re very interesting little creatures, because most of the time, and this is just a drawing of what they sort of look like. Most of the time, they’re in what’s called the M2 anti-inflammatory mood. What that means, these little guys pick up dirt, debris, Recycle them. Turns on an enzyme called interleukin-10 that’s anti-inflammatory. And just kind of does general housekeeping. And just kind of does general housekeeping. However, when a trigger comes along. However, when a trigger comes along. They… it’s the same glial cell, but it moves over to a very pro-inflammatory enzyme. A pro-inflammatory glial cell. And it triggers these 3 enzymes, Actually, these four. That are pro-inflammatory. Tumor necrosis vector alpha, Interleukin-6. NF Kappa B, Inos. Now, these create inflammation. So you might think, well, why is that good? Well, if you have some foreign invader, virus, bacteria coming in, parasite. If you didn’t have these guys coming to the rescue, you would just die of infection. So, these guys are your friend unless they’re your worst enemy. Because TNFA, and we’ll show you when we actually do a demo account, TNFA can be overactive. So, in other words, it over-responds. Interleukin-6 can be overactive. And if Kappa-B can be overactive. The INOS, and I’ll explain each of these as we go through a demo, can be overactive. Now, what that means is, you’re very good at killing virus and bacteria. But this is where autoimmune disease comes in, and just inflammatory conditions. Now, this is just speculation, but we think what happened is, as you know. Thousands of years ago, we didn’t have refrigeration, we didn’t have sewer, we didn’t have pure water, and we didn’t have antibiotics. So, if you made it to 40, you were an old-timer, because everybody was dying of infection. So, what we believe happened is, by what’s called natural selection, Having these overactive. A thousand years ago was to your advantage. Dr. Deb Muth 00:22:31 Hmm. Bob Miller 00:22:32 But now… We have pure water, we have refrigeration, we have sewers, we have antibiotics. But now we have environmental factors that are stimulating them. Now it’s to our disadvantage. And we’ll talk about that a little bit as it relates to the hemochromatosis genes and maybe the G6PD. Dr. Deb Muth 00:22:48 Yep. Bob Miller 00:22:49 Now, why are we becoming so inflamed? Let’s look at the triggers. Now, one of my, favorite expressions is. I was born all the way back in 1954. Dr. Deb Muth 00:23:01 And it was a different world back then. Bob Miller 00:23:05 These are some of the triggers. And we’ll get into these, but right now, high fructose corn syrup, And the high-fat diet. High fructose corn syrup only came about in 1968. So now we’re being exposed to high fructose corn syrup. Then… we didn’t have these, these viruses like COVID. Dr. Deb Muth 00:23:26 Yeah. Bob Miller 00:23:27 Now, there’s now pretty strong evidence that COVID Was actually, you know, made as a gain of function. It’s debated, and I’m not taking an opinion on it, but there’s some people who believe Lyme disease was also a part of experimentation. Dr. Deb Muth 00:23:40 Go. Bob Miller 00:23:41 Then we have molds, and it appears as though mold is getting stronger. you know, 20 years ago, when I was seeing folks, mold wasn’t on the radar. I would say 7 out of the 10 folks we speak to today have mold problems. Yeah, 20 years ago, we talked more about mold allergy being an issue versus mold toxicity being an issue. Right. So… I know some folks are, you know, speculating what’s happening, but one of the theories out there is that EMF is strengthening mold. I don’t know if you ever heard that theory, and I don’t… Dr. Deb Muth 00:24:13 I have. Bob Miller 00:24:14 I’m not claiming it’s true, but it’s an interesting theory. Then even, you know, your black mold from water-damaged buildings. Then our air pollution is getting worse. We’re getting more toxic metals. Dr. Deb Muth 00:24:26 You know, if we have a… Bob Miller 00:24:27 You know, we’re gonna look back someday and say, what were we thinking, smearing aluminum into our armpits? The, what were we doing putting mercury in our teeth? Then, you know, glyphosate. When I was a kid, there was no glyphosate. So, all of these herbicides and pesticides. Polychlorinated biphenols, And then EMF. So, we love our cell phones, you know, and I think unless you, or in the middle of the desert, or down in a cave, you’re being exposed to EMF somewhere. So, you know, we have our cell phones with us, we have, We have Wi-Fi, the towers are everywhere. And we don’t know long-term, but we may find that this can… this creates some inflammation. And I don’t know if you get any folks, but do you have any folks that have… are they EMF sensitive? Dr. Deb Muth 00:25:16 Oh yeah, we have a whole bunch of them. Bob Miller 00:25:18 Yeah, and then if you have any TBIs, So, plenty of things here. that will stimulate into the microglia, M1. Now, you could say, well. We’re all pretty much exposed to the same thing. Why do some people get hit harder than others? So here’s where we’re gonna start. There’s an enzyme called Nrf2 and RF2. And Nrf2 is the enzyme that senses when there’s inflammation. And turns on hundreds of anti-inflammatory enzymes. We’ll show when we do the demo, you can have genetic weakness on NERF2. And NERF2 inhibits and slows down microglia M1. supports M2. Now, if it’s not complicated enough, there’s an enzyme called KEEP1. And KEEP1 inhibits NRF2. And you can actually have gain of function on keep 1, that makes Keap 1 stronger. So… A lot of the people who land on my doorstep So… A lot of the people who land on my doorstep Both parents gave a mutation on KEEP1, making it overactive. Both parents gave a mutation on KEEP1, making it overactive. Dr. Deb Muth 00:26:31 Hmm. Dr. Deb Muth 00:26:31 Hmm. Bob Miller 00:26:32 Suppressing Nrf2, nerve 2 might be weak. So, nobody’s putting the brakes on, M1. And by the same token, Nerve 2 supports M2. Then there’s a process called mTOR and autophagy. mTOR stands for mammalian tard of rapamycin, the growth of new cells. And then autophagy, taking our dead cells and recycling them. We need a balance between the two of them. If we didn’t have mTOR, the sperm and the egg would never become the baby, the baby would never become the adult, we wouldn’t make new cells. But our cells are constantly, you know, the old cells dying off. Autophagy is where we take that debris from the cell and recycle it, just like a farmer Plows the crop under at the end of the year. The dead plant then becomes the fuel for the spring, your dead cell becomes the fuel for the spring, and that’s autophagy. So we’re gonna look back someday and say, what were we thinking? We give our animals growth hormones so they get fatter faster. Oh my. So, we consume those animals, and inventory runs faster. Now, for anybody who’s, You know, maybe above 40, 45 years old. Think back when you were 12, and what did girls look like? They were primarily flat-chested little girls. Now they look like 16-year-olds. Because environmentally, we’re jacking up mTOR. So, mTOR stimulates microglia M1, suppresses microglia M2. Probably 80% of the folks we visit with. This is the part of the problem. NRF2 is weak. mTOR is strong. Environmental factors come along. And this guy gets carried away. He doesn’t do that burst and move back. Stays here. We’re calling that How environmental factors create a locked-in, pro-inflammatory. and neurotoxic phenotype. In other words, once it starts, it just keeps… Feeding upon itself. Alright, so what happens now when microglia is overactive. it triggers these 3 enzymes, TNFA, N of kappa B, And interleukin-6. Each one of these can have genetics that make them run stronger. Then it stimulates an enzyme called NLRP3, Which makes what are called inflammasomes. Now, guess what inflammasomes can be? Your best friend or your worst enemy? Because they will, if you’ve got, again, a virus or bacteria, or possibly even some bad cells in the body. They will zap them. Well, that’s good. Unless it’s overactive. Unless it’s overactive. And then what it does, through interleukin-1 beta, makes excess glutamate. And then what it does, through interleukin-1 beta, makes excess glutamate. Anxiety, gut inflammation, OCD, ADD, autism. And, you know, glutamate, we’ll talk about that a little bit, but glutamate makes you intelligent, highly motivated go-getter. but can also be excitatory. And then, look what it does. Let’s see, do I have the drawing tool here? Yes, I do. Okay. So, it comes down through here, Makes the glutamate. Comes back up through here. through the ADORA 2A enzyme, Then we’ve got a feedback loop that feeds upon itself. Then, through interleukin-18, we make histamine. and mast cells. And then through histamine receptor site number 1, we come back and spin it. And now you’ve just got this spinning feedback loop. So, the glutamate will make you anxious, the histamine will give you allergies and make you anxious. And you’re allergic to everything, and you’re feeling horrible. Now, it doesn’t end there, Dr. Dad. It then goes on to make something called gast dermins that creates pyroptosis, where it actually starts punching a hole in the cell membrane. And you’re only going to be as healthy as your cells are. Just a little background. You know, we’re made up of trillions of cells, and each one of them has what’s called a lipid bilayer, made from lipids, which comes from fats. And you’re only going to be as healthy as those membranes are. So that’s why we coined an interesting phrase. Cellular CPR. Construct the cell. Protect the cell. And restore the cell membrane. And we believe that’s going to be revolutionary in the functional medicine world. So… It’s not hard to figure out that if you start punching holes in the cell membrane, that’s not a good thing, okay? Bob Miller 00:31:22 Now… There’s an interesting molecule called NAD. Thicotide adenoside dinucleotide. And anybody who’s in the, you know, listening to the health podcasts and things, they’re… They’re, they’re learning about NAD. And I’m going to show you a chart later, all the good things that NAD does, but For the most part, it helps what’s called sirtuins. And sirtuins are quite interesting. If anybody’s looking at longevity. The sirtuins is where they’re looking at.Because sirtuins turn on good things. Turn off bad things. And I’ll show some charts on that later. So for right here, this sirtuin uses NAD, to slow down NF-kappa-B. CERT 2 uses NAD to slow down an ORP3. So, if we’ve got genetic weakness on these, or we don’t have enough NAD, We don’t hold this pathway back. Make sense? Dr. Deb Muth 00:32:24 Yeah, makes perfect sense. Bob Miller 00:32:25 Now, I’ll show this a little bit later. So, people are like, oh, well, I’m gonna start taking some NAD. Dr. Deb Muth 00:32:31 Right. Bob Miller 00:32:32 And there’s functional doctors who give NAD intravenous. It was just this morning, I was talking to a woman who said, Oh my gosh. I went and got intravenous NAD, and it took me a month to recover from that. Dr. Deb Muth 00:32:45 Hmm. Bob Miller 00:32:46 what happens is, and I’ll show this in a little more detail, there’s an enzyme called CD38, that’s stimulated by NF-kappa-B. And it takes NAD, To make intracellular calcium. that stimulates NLRP3 and actually makes things worse. So, if we have this guy upregulated, and I’ll show a chart what does that. taking NAD will make you worse. Again, when I go into the software, I’ll show you that whole pathway, so… I would encourage people, you know, just don’t go out and start taking massive amounts of NAD, you know, stick your toe in the water, see how you do. Because everything you’ve heard about, how good it is, is true, unless this guy says, oh, thank you very much, let me make more inflammation. Now, this might be part of our innate immune system, that if we have some pathogen that’s gonna kill us. By golly, we want that to happen. But if this is happening by environmental factors, Then it’s detrimental. So the immune system that protected us a thousand years ago now might be turning on us because of the environmental factors that we showed earlier. All right. Then there’s an enzyme called PARP that’s NAD-dependent, and that actually repairs strain breaks in your DNA. Now, the next thing that happens… is there’s an enzyme called NADPH oxidase that gets stimulated. and something called INOS. Now, I’m sure most people know about nitric oxide. It’s a gas that dilates your blood vessels. That’s why sometimes they’ll even give people drugs, nitroglycerin, to boost their nitric oxide. That’s why people are doing beetroots and other things to boost their nitric oxide. But there’s an OS3 enzyme that makes the nitric oxide that’s good for blood flow. But there’s an INOS That makes nitric oxide to kill pathogens. probably might be the third or fourth time I’ve said this. That’s a good thing, unless it isn’t. So, if it’s killing some pathogen, great. It was just misfiring. it combines… With superoxide that’s made by this enzyme, and makes something called peroxynitrite, which is one nasty free radical that chews you up and spits you out. So, the NOx enzyme, NADPH oxidase, uses NADPH, To make this free radical called superoxide. If we have time, we’ll get into it. NADPH is what your body needs to recycle your antioxidants.So, I coined the phrase, the NADPH steel. Where the NOX enzyme takes this very important NADPH, And rather than being useful, makes superoxide. Now, again, is that fine if you’ve got some bacteria to kill? Of course. But if it’s just chronically running, it’s just making all this chronic inflammation. Then it makes something called hydrogen peroxide. And we need to clear hydrogen peroxide by 3 enzymes, catalase, thyroid reduction. And glutathione peroxidase. If we have genetic issues on here, or we don’t have the cofactors. There’s something called the Fenton reaction, discovered in 1895 by Dr. Fenton. Where hydrogen peroxide combines with iron to make what are called hydroxyl radicals. And guess what they do? They create lipid peroxides, That damages your cell membranes. Now, again, the body’s pretty darn amazing. We have glutathione, And here’s where your body’s taking glutathione and recycling it. But look who’s needed to recycle it. NADPH. So, if this guy up here is chewing it up, We don’t recycle our glutathione. And then an enzyme called glufon peroxidase 4, Takes this damaged lipid and repairs it. So, here we’ve got this protecting, we want to protect it by not having this happen. But then we also need this guy to do the restoration. So, there’s a lot that can go wrong in here, Dr. Deb. Dr. Deb Muth 00:37:07 There’s a lot that could go wrong. And I can imagine some of my listeners are thinking that lipid peroxidase, is that the same thing as what they’re thinking of when we talk about lipids and cholesterol? Is that the same process that’s happening there? Bob Miller 00:37:22 Well, no, no, the lipids can be used to make cholesterol, but here we’re talking about where they’re going to build the cell membrane. And they’re being… and they’re being, destroyed. If anybody would like to see a visual representation of this, just go on YouTube. And type in, ferrooptosis Animation. cool little video, it’s about 3 minutes long, and it shows the lipids coming over, being oxidized, and now GPX4 fixes them, so… YouTube, Pharaoptosis Animation, cute little video. It’s just that really… Shows vividly what we’re… what we’re talking about here. Now, this is… Dr. Deb Muth 00:37:59 And so this is very common, too. Like, a lot of people do hydrogen peroxide IVs. Dr. Deb Muth 00:38:04 And so, if somebody doesn’t know their genetics, they could have a problem with doing those, just like they could doing the NADHIVs, correct? Bob Miller 00:38:13 Sure, yeah, yeah, yeah. So, I’ve talked to so many, you know, of course, the hydrogen peroxide kills pathogens. I mean, that’s what it does. So… but I’ve spoken to so many people that said. I had one client that said they’ve never been the same after having one hydrogen peroxide infusion. Dr. Deb Muth 00:38:30 Interesting. Bob Miller 00:38:31 Yeah. So… it can be… I see why people use it, because it. Bob Miller 00:38:36 pathogens, But on the other hand. And now’s a good time to speak about… I don’t have it on here, but there’s a, there’s an enzyme called the HFE gene. And that is what causes you to absorb iron. And there’s mutations in it that cause something called hemochromatosis. Were you overabsorb iron? Now, true hemochromatosis is when both parents give you a mutation. But there’s now growing evidence even a heterozygous can cause a little bit more iron absorption, not to the human chromatosis point, but overabsorption. So, if you overabsorb iron, And you have too much hydrogen peroxide that’s not cleared, All kinds of inflammation. Now, what’s happened is sometimes this inflammation Will damage the red blood cells. And some well-meaning doctor says, oh, you need some iron. And they take iron and it makes it worse. So, can’t tell you how many people I’ve said, you’ve got the overabsorption of iron, and they say, well, that can’t be right, because I’m low in iron. Well, that could be because it’s being chewed up here. Dr. Deb Muth 00:39:40 Sure. GPX1 and TXN turn it into, to water. The, catalase turns it into water and oxygen. Dr. Deb Muth 00:39:58 Now, I see a lot of my clients who have mutations or SNPs on that GPX gene, on that glutathione gene. And they really struggle to clear a lot of their toxins. Bob Miller 00:40:12 Sure. Dr. Deb Muth 00:40:14 Yeah, absolutely. Well, GPX4. Bob Miller 00:40:18 is what, repairs, but you can see GPX1 Is what uses glutathione. To turn hydrogen peroxide. So, but it all depends upon having enough glutathione. Dr. Deb Muth 00:40:30 Yeah. Bob Miller 00:40:31 Well, guess who controls making a glutathione? Dr. Deb Muth 00:40:34 Nerf 2. Bob Miller 00:40:37 So, if you have a keep one weakness, or strength to two… I’m sorry, keep one is too strong. Nrf2 is too weak. You don’t make glutathione. So, when a lot of people do that, it’s like, well, I’m gonna take glutathione. Dr. Deb Muth 00:40:51 Right. Bob Miller 00:40:52 And some do great, and some do poorly. You know, because… and I’ll show this on one of the other charts. You can see here that the, The glutathione has to be recycled. And if we don’t recycle it, it actually turns into superoxide free radical. So… NADPH are the cofactors, For taking the oxidi… here’s oxidized glutathione, here’s reduced. So, this is a good glutathione. After it does its job, you can see it becomes oxidized.We need to recycle it. Well, if we have weakness on the enzyme that does that, or a weakness in Nrf2, or not enough NADPH. The oxidized glutathione never gets recycled. So, I’ve talked to a lot of people who said, oh, glutathione made me so sick, and say, well. Dr. Deb Muth 00:41:43 Yeah. Bob Miller 00:41:44 You need it, but you need to recycle it. Dr. Deb Muth 00:41:46 Can you speak for just a brief moment, too, about MTHFR? That is a very popular gene, it’s all over social media as the major gene, but can you speak to a little bit about that, and how that fits into this whole process of things? Because it is just such a small piece. Dr. Deb Muth 00:42:04 understanding genetics. Bob Miller 00:42:06 Yeah, to be honest, it drives me nuts. Dr. Deb Muth 00:42:08 Me too. Bob Miller 00:42:11 Alright, so… You know, there are people on social media I won’t say what I think, I’ll be kind. But… But the, And, you know, they might mean well. But they talk about, if you have MTHFR and COMT and PEMT, that’s… oh my goodness, that’s horrible, and we’ll fix that for you, and you’ll be fine. Bob Miller 00:42:36 it just irritates me to no end. And it really could get anybody who’s doing this legitimately in trouble. I mean, I’m afraid someday, you know, there might be some cracking down on this kind of nonsense. Now, to answer your question about MTHFR. Dr. Deb Muth 00:42:51 I mean, it really is, but I’ll tell you what, why don’t we hold that thought until I go to another map and I can actually… Okay. Bob Miller 00:42:56 But the real… the cliff notes is the MTHFR puts a methyl group on your folate, which is needed, but it has gotten way, way, way too much attention. And people learn they have MTHFR, and they start taking a multivitamin with methylfolate, then they take a B vitamin with methylfolate. Dr. Deb Muth 00:43:13 And they’re pushing it too hard. Bob Miller 00:43:15 Yeah. So I can’t tell you how many people I’ve helped by saying, stop it. Dr. Deb Muth 00:43:20 Yeah, take less of it. Bob Miller 00:43:21 Take less of it, yeah. So, yeah. Yeah, there’s a… If somebody, say, ranked the enzymes at their level of importance, MTHFR might be 40 or 50 on a scale of 100, you know. Keep one Nerf two. big deals. Dr. Deb Muth 00:43:40 deals. Bob Miller 00:43:41 NQO1 that I didn’t even talk about yet, NQO1, takes your, NA… your NAD goes into NADH, To make electrons for the electron transport chain. you need NQ01 to bring that back. If that’s not working, and I’ll show you on the NAD map how disastrous that can be. Now, the next piece is here, and I think You know, if you talk to any school teachers and say, if you’ve taught for more than 10 years, how are the kids today? Every one of them says, more ADD, ADHD, more autism. Just look at human beings, we’ve never been so agitated. You know, everybody, and it might be a social media thing, but people take a position on something, and if anybody doesn’t share that position, they view them as the enemy. Dr. Deb Muth 00:44:29 And it’s kind of scary what’s happening to us. Bob Miller 00:44:33 So, we can’t agree to disagree anymore. We see anybody who has a differing opinion as the enemy. And, you know, there was… there’s people that didn’t have Christmas dinners together, because they had political differences, like… Dr. Deb Muth 00:44:44 Excuse me. Bob Miller 00:44:45 can’t you put your political differences aside to have Christmas together, you know? Dr. Deb Muth 00:44:49 Right? Bob Miller 00:44:50 become that, you know, no matter what your position is, and I’m not saying anyone’s right or wrong, I’m just saying. You know, in the old days, they used to say that the Republicans and Democrats in Congress would argue policy and then go have dinner together. And now everybody’s all up in arms, angry. Dr. Deb Muth 00:45:05 Yeah. Bob Miller 00:45:06 So… There’s likely multiple reasons for that. But let me show you one of them. That, you know, to what degree this is… very important, we don’t know, but I think We’re beginning to believe this is very important. So, there’s something… there’s a neurotransmitter called GABA. And God buys the don’t worry, relax, be happy. Chill. Okay. Dr. Deb Muth 00:45:31 Nobody has enough of that anymore. Bob Miller 00:45:33 Well, yeah, you’ll be surprised what I’m gonna show you. So, let me see if I can find a, Let me see if I can find the right slide here. Let me look for it here. So, there’s something called a GABA receptor site. And here you can see… This is a neuron, and this is where you, The neuron normally is excitatory. However, there’s normally low chloride in the neuron. Dr. Deb Muth 00:46:09 Hmm. Bob Miller 00:46:10 So, GABA itself is neither relaxing. For excitatory, all GABA does, it opens up what’s called a chloride channel. And then chloride, which has a negative charge, will flow into the neuron. Follow me there? Dr. Deb Muth 00:46:26 Yep. Bob Miller 00:46:27 And as it does, it changes this from a positive charge to a negative charge, And it’s relaxing. and inhibitory. Dr. Deb Muth 00:46:34 Hmm. Bob Miller 00:46:36 Now, on the other hand, there’s enzymes called NKCC1, That will push chloride in. and KCC2 that will bring chlor… oops and bring chloride out. And then there’s a sodium channel. And, sodium has a positive charge. And glutamate will push that in. So, as long as this is happening. And GABA says, receptor sites, open, chloride goes in, Chill. However, If NKCC1 Pushes extra chloride in. KCC2 doesn’t pull it out. and GABA hits the receptor site, the GABA comes flowing out, Sodium comes in, And now it’s excitatory. So Gabba didn’t change. GABA just opened the receptor site, that’s all it does. Dr. Deb Muth 00:47:33 Yeah. Bob Miller 00:47:34 But it’s the chloride balance that’s going to determine whether this is relaxing or not. Now, these are the things that go along with when they lose that KCC2 or gain NKCC1. Pain and sensitivity, burning electrical, neuropathic pain. Normal touch hurts. Sound and light sensitivity. Tinnitus can flare. Headaches and migraines. Seizure tendency. Body jolts. Spasticity, cramps, stiffness, startle reflex. Trouble falling asleep, non-restorative sleep. Anxiety, stress, reactivity, that’s what we have now. Hyperarousal, panic-like surges, irritability, racing thoughts. Brain fog, slowed processing, working memory slip-ups. Mental fatigue. Episodes of racing hearts, sweaty palms, guts on edge. Those are all the things that happen when this GABA switch occurs. Now, here’s what happens, and this is what I’m going to be presenting at an autism conference. When you have a newborn, they need that NKCC dominant to develop. By early childhood, it should… or, sorry, early adulthood. we should move over to the KCC dominant, that’s the taking the chloride out. Nice-looking 25-year-old boys, functioning very well. However, when we get microglia M1 upregulated. Because of environmental toxins, processed foods, Tylenol, aluminum. they stay in NKCC1 dominant, and there’s ADD, ADHD, Autism, the whole spectrum. because… They’ve not moved over to the… They’ve not moved over to the KCC2. And again, this is caused by… Environmental factors. Stimulating the microglia. And then, interleukin-1, interleukin-18 weakens KCC2, interleukin-1 beta, Strengthens NKCC1. high chloride. We open up the chloride channel, In Rebell Excitatory. So, I think when, When the pediatricians get ahold of this, they’re going to be very excited to know that This could be why we’re seeing such a rise, and not just autism, but ADD, ADHD, anxiety, the whole shit mess. Dr. Deb Muth 00:49:58 thing. Bob Miller 00:49:59 Yeah, so… and you can see NF-kappa-B stimulates that. These stimulate it, and I think that’s why everyone’s getting so anxious. Now, there’s a little bit more to it, and we’ll get into this when we look at some of the maps, but… The, the glutamate, Which is excitatory. will stimulate the NMDA receptor, make more glutamate, And glutamate will inhibit KCC2. And then we also need an astrocyte To, take both ammonia And glutamate, and… Turn them back into glutamine. And I’m going to talk to you a little bit about arachidenic acid, and if we have too much arachidenic acid. or TNFA is upregulated, that doesn’t happen. Ammonia goes up, and there may be multiple reasons for this, but this is a reason why some of the autistic kids do flapping. Dr. Deb Muth 00:50:49 Hmm. Bob Miller 00:50:50 Because they’re not clearing their ammonia. And you can tell if somebody has high ammonia by… they get that old person smell, you know. Dr. Deb Muth 00:51:00 Yup. Bob Miller 00:51:01 your vehicle cycle’s not taking out the, the ammonia. Now, last pathway here. There’s growing interest in mast cell activation. So, back here, we talked about peroxynitride. And that will stimulate mast cells, and those are white blood cells that are your best friend, unless they’re your worst enemy. Then it’ll make histamine. And there’s enzymes called histidine decarboxylase that’ll make more. Dr. Deb Muth 00:51:28 I’m sure everybody’s heard of DAO, the enzyme that degrades histamine. Yep. Bob Miller 00:51:31 We can have genetic weakness, we don’t make that. There’s an enzyme called histamine and methyltransferase, That, That breaks down the histamine. Then if we don’t do that, it’ll get stuck in the histamine receptor site. And then it’ll make something called, renin. Which will cause angiotensinogen to turn into angiotensin. One, that turns into angiotensin II,And that’s where people make aldosterone, where they’ll get the, The swollen ankles and high blood pressure. But interestingly, there’s an enzyme called ACE2, that takes this guy and turns it into angiotensin 1-7, Which is anti-inflammatory and also inhibits… TNFA. Now, you can have weakness on ACE2, But… and anybody’s saying, that sounds familiar? Dr. Deb Muth 00:52:25 That’s where COVID comes in, using ACE2. Bob Miller 00:52:28 And now we just found there’s literature that if you get COVID long enough, it can actually make ACE2 not be able to work as well. So look what it does. It comes down here, stimulates the NADPH oxidase, More superoxide. More peroxynitrite. And we’re on a cycle here. We’ve actually named this the Home Cycle Hypothesis, the proposed feed-forward loop. That just keeps feeding on itself. All being caused by… Primarily, The environmental factors. But hitting those who have genetic weakness the hardest. That’s why. Dr. Deb Muth 00:53:08 To the people. Bob Miller 00:53:09 Don’t live in a moldy house. One person is sick as can be, and the other person says, well, you must be imagining things, because I don’t feel anything. Dr. Deb Muth Yeah. Same thing with long haul, right? Two people can both get sick, one gets sick and never seems to recover, and somebody else gets sick, and they have absolutely no problems with it at all. Bob Miller 00:53:30 Sure. Well, think about it, if you get COVID, and ACE2 is weak, and some of this other stuff is going on. This thing just starts feeding upon itself. Dr. Deb Muth 00:53:38 Keep creating more inflammation, more complications, nothing’s calming down. Bob Miller 00:53:43 Yeah. Now, you, you ask about, MTHFR. So, this is the, this is the, the software called Functional Genomic Analysis. There’s a demo report we have. So, let’s talk a little bit about, MTHFR. So, we actually have a map called a methylation map. Now, what happens is, when you do your saliva test, you, you know, you spit, you put some saliva. in a collection kit, goes to a lab, takes out the DNA data, sends it to the computer, and now you can actually see it visually. Okay. So, it’s gonna take a second for this, data to load up, it’s, and each of these Circles, each of these ovals, is an enzyme. And the data gets loaded up to see where it is. So, until it gets loaded up here, I didn’t preload this. There it goes. So… The primary thing about methylation is There’s a nasty substance called homocysteine that, if it’s too high, can really be detrimental. The body takes methylfolate, and combines with methyl B12, To bring this back up to methionine. And then through the MAT genes, we make SAMI, S-adml methionine. Which is involved in so many processes. Then after it does its thing, it turns back into homocysteine. And this thing needs to keep spinning around. That’s why, you know, it’s a good idea to keep homocysteine at, do you have a number that you’d like? 7, 8? What do you like for a number? Dr. Deb Muth 00:55:24 Yeah, I like mine below 7. Bob Miller 00:55:26 Yeah. So if the homocysteine goes too high. It, caused all kinds of problems. So, here’s where you ask about the MTHFR. So, here you can see on this individual. I click on MTHFR, and you can see it comes up here, here’s the C677. And you can see here where it says, variants. I’ll… I’ll draw in case somebody’s having a hard time seeing that. So, you can see there’s nothing in there. That means there’s no genetic mutations. If one parent would have given a mutation, there’d be a 1. If both parents did, there’d be a 2. Now, here’s why Yes, methylation is important, I’m not saying it isn’t important, but look at this MTHFRC677. In my software. Only 42.5% of the population does not have a mutation. 44.7% have won. 12.9 have 2. So, this isn’t some rare, oh my god, I’m gonna die… Kind of thing, yeah. Dr. Deb Muth 00:56:27 Right. Bob Miller 00:56:28 So, And then what happens is that, and again, I’m not dismissing methylation, I… we could do a whole show on methylation. Bob Miller 00:56:36 get it. But I think that what people are doing is they’re, they’re learning about MTHFR, they get it measured, they panic. They start taking massive amounts of methylfolate, which many times is to their detriment. Dr. Deb Muth 00:56:50 Well, it’s… and isn’t it true, too, with MTHFR, like, you have to also look at MTR, MTRR, and the more we stack up of those, the more complicated than MTHFR can be. It’s not… it’s not as simple as just saying MTHFR 677 versus 1298. It’s more complex than that, kind of like what you’ve already shown with some of the other things. There’s more to it than just that one little sliver. Bob Miller 00:57:17 Oh, sure, well, let’s take a look. So, remember I said there’s a cofactor? One of the cofactors is called FAD. Just a Bob Miller observation, that’s all. But when people have trouble with their riboflavin and they don’t have enough FAD, They’re doing much worse than people who have just a C677. So, right here, you could have perfect C677th. And if you don’t have the cofactor, it’s not gonna work, okay? Dr. Deb Muth 00:57:48 And as you said, there’s an MTR enzyme. Bob Miller 00:57:51 that takes methylfolate and methyl B12, to spin it around. So, here on this individual. here’s your… here’s your B vitamins, or I’m sorry, your B12s. There’s an enzyme called TCN1 that takes it from the stomach into the blood. Then there’s other enzymes that take it from the blood into the tissue. And if you’re having trouble here. Well, then you’re not going to have this working, so… Even if you don’t have MTHFR, And you have MTR, like this, no, I’m sorry, this person doesn’t. But they have the MTRR, and then they don’t have enough B12, this isn’t gonna work, aside from that. And then there’s a middle pathway. And then there’s enzymes called the MAT1. they take the methionine to the salmon. If that’s not working, we stick… we get stuck in methionine. So, it’s, it’s not just an MTHFR. And then, one of the things that people forget about. is through these CBS enzymes and CTH, We make cysteine, which is needed to make glutathione. The master antioxidant. So, it really is that… I call it the, The 3D chess game played underwater. Dr. Deb Muth 00:59:07 It really is. I mean, I see people who have CVS, COMT, glutathione, MGHFR genes. And some of them function just fine. Like, they have Like, I look at this person and I’m like, oh my gosh, I don’t know how they’re functioning because they’re double mutated on so many pathways, but yet they don’t have a lot of symptoms, they don’t have a lot of complications. Somehow their body has figured out a way to adapt to what it has so it can stay alive and it can function at a high functioning level. Bob Miller 00:59:36 Yeah, and they may be, you know, eating right? Yeah. Staying out of a moldy house. reducing stress. So, it’s diet, it’s stress, it’s genetics, environmental factors. So, yeah, we can’t just say somebody’s gonna be good or somebody’s gonna be bad. You know, some people get scared, oh, I got all these, it’s like, well… Bob Miller 00:59:56 Are you living in a moldy house? You know, and if you live in a moldy house and your glucuronidation pathway doesn’t do well, or if you’re, you know, a smoker, or you’re constantly eating junk food, I mean, all. Bob Miller 01:00:07 things come together. Although, you know, when we focus on genetics, we’re well aware that this is just a piece of it. You know, you could have identical twins, Genetically, and if one… Is exposed to mold and smokes and drinks and stressed out. They’re gonna be a whole lot sicker than their sibling. Bob Miller 01:00:28 Yep. Dr. Deb Muth 01:00:29 Yeah, it’s that concept of taking twins, and one gets raced with one family, and one gets raced with another family, and they don’t have the same… problems that… that each other have, you know? It’s a very unique situation, we don’t think about that enough. Bob Miller 01:00:44 Alright, so again, genetics loads the gun, environment pulls the trigger. So, if you’ve got a loaded gun, but you don’t have the triggers, you’re okay. Dr. Deb Muth 01:00:53 Yeah. Bob Miller 01:00:54 Yeah. So, remember I said I was going to talk about NAD? So, here’s NAD, and what it does, it turns into NADH. And what NADH does, it, Comes down this pathway, what’s called the electron transport chain. And that makes your ATP, that’s your energy. So, if this wasn’t working, we wouldn’t be alive, because we wouldn’t have energy. So it donates an electron, that’s why it’s called electron transport chain. So, we need NAD, To make this, to make the energy. But remember I said that NQ01, this would probably be, like, on my top 10 list of… Bob Miller 01:01:36 Much more important than MTHFR. This one takes NADH back to NAD. If we’re stuck over here, We’re low in this NAD+, But what happens is, NQO1 also provides CoQ10. And CoQ10 Is what’s needed for the electron transport chain to flow. So if we get too many electrons up here. And they don’t turn them into energy. They make a nasty free radical called superoxide. Okay. Now, NAD plus also makes NADPH, And that is needed. Remember I said we need to recycle our antioxidants. So, if we have a problem with FAD from riboflavin. Yeah, we don’t have enough NADPH, Glutathione’s not getting recycled, and you’re gonna be inflamed. And you take glutathione, you’ll feel worse. There’s another enzyme called thimoredoxin. Same thing, needs NADPH and FAD. And same way with your nitric oxide, there’s an enzyme called NOS3, That makes the nitric oxide that dilates your blood vessels. And if we don’t have enough NADPH or fat, You’re gonna make superoxide. Rather than nitric oxide. Now, remember
In the age of AI, do you feel that your future is more uncertain?
This biology student-turned model had a penchant for writing about sexual wellness. She just had to find a way to make money with it—and she did. Side Hustle School features a new episode EVERY DAY, featuring detailed case studies of people who earn extra money without quitting their job. This year, the show includes free guided lessons and listener Q&A several days each week.Show notes: SideHustleSchool.comEmail: team@sidehustleschool.comBe on the show: SideHustleSchool.com/questionsConnect on Instagram: @193countriesVisit Chris's main site: ChrisGuillebeau.comRead A Year of Mental Health: yearofmentalhealth.comIf you're enjoying the show, please pass it along! It's free and has been published every single day since January 1, 2017. We're also very grateful for your five-star ratings—it shows that people are listening and looking forward to new episodes.
Dogs aren't struggling because they haven't been exposed to enough—they're struggling because of how their nervous system is processing what they've experienced.In this episode, we break down the role of emotion in exposure work and why neutrality is the true marker of success. You'll learn how to move beyond “just getting them used to it” and instead begin shaping experiences that help your dog feel safe, regulated, and capable in a stimulating world.dogspeak101.comdogspeakgeek.thinkific.compatreon.com/dogspeakAggression and Reactivity SummitLive Q&A
The brain is the central driver of our thoughts, memories, relationships, and ability to love, and it's far more resilient than once believed. Neuroscientist Dr. Tommy Wood, author of the book, The Stimulated Mind, explains that while genetics can influence the risk of cognitive decline, nearly half of dementia cases may be preventable through lifestyle choices like physical activity, good nutrition, quality sleep, mental stimulation, and social connection. Everyday forgetfulness is usually due to stress, distraction, or lack of sleep—not early dementia—but it can serve as a signal to improve habits. Maintaining brain health requires balancing challenge and recovery: engaging in meaningful, mentally demanding activities while allowing time for rest. Ultimately, staying mentally sharp depends less on fate and more on consistently using and caring for the brain through purposeful, active living. Link to book: https://www.penguinrandomhouse.com/books/751292/the-stimulated-mind-by-dr-tommy-wood/ Follow Dr. Wood on social media:Website: https://www.drtommywood.com/Instagram: https://www.instagram.com/drtommywood/LinkedIn: https://www.linkedin.com/in/thomas-wood-35b685a8/Podcast: https://www.drtommywood.com/podcast
For the Dyosa listener, this is a helpful guide to self-discover and know your pleasure points. For the Supremo-to-be, this is a 101 in knowing the points and crevices that makes a Dyosa moan in delight! Hosted on Acast. See acast.com/privacy for more information.
Dearest listeners,Are you turning over in your mind the events of a mere season, desperately wondering which sibling might next grace our screens? Have you looked at all the evidence only to find you're still not sure? Join us for a brief but puzzled conversation where we try and decide which Bridgerton's love story we think is written in the stars (and seeds).Could we bark-ing up the wrong tree with Philoise? Will Fran's missing puzzle piece ever find her way back to the ton? Will the winds of change blow the seasons out of order yet again? One thing is for certain: we need to KNOW. *Follow UsPatreon: https://www.patreon.com/whatabarbpod/ Instagram: https://www.instagram.com/whatabarbpod/ TikTok: https://www.tiktok.com/@whatabarbpod YouTube: https://www.youtube.com/@WhataBarbPod
The Awareness Space - Health & Wellbeing - Podcast and Movement
In this episode we have a Q & A. Owen and his co-hosts Alice Cantwell & Philippa Balazs discuss the topics brought to us by you. This episode includes how to work with overstimulation and seeking stimulus, how to cultivate and sustain friendship an ND'er and how nature can help us. Below are the questions we cover and the time stamps. 02:37 - Question One - When I get really wired and overstimulated I end up scanning on social media or doing things rather than creating space and calm and no screens. How can I work with this?. 09:40 - Question Two - I find getting outside into nature or the country really helps. Do you think this is a common tip for ND'ers 17:10 - Question Three - I struggle with friendships. I ruminate over what the connection means, questioning their behaviour and wondering if they care. What do you do to help yourself let go and just be with friendship dynamics. Want us to talk about a topic you would like unpack then DM us on social media or email ndandfree@gmail.com Check out our Linktree To Explore all our Partners and Services - https://linktr.ee/ndandfree MORE ON ALICE Hear her 1-1 Episode on the Pod - Episode 30 - https://open.spotify.com/episode/7IkVftqDPDbtJlpMocTVWL?si=e420b64300b84e7d Alice is a Neurodivergent Assessor and speech and language therapist and runs her business Bold Mind ND. Follow links for more on Alice's and her work LinkedIn https://www.linkedin.com/in/alice-cantwell-80aa7a229/ Facebook - https://www.facebook.com/share/1AVjCMJFD6/ Instagram - https://www.instagram.com/boldmindsnd?igsh=MWEyd2Y2NzN0dmx5aA== MORE ON PHILIPPA Hear her 1-1 Episode on the Pod - Episode 50 - https://open.spotify.com/episode/7kGEQULLpUjqosWh7wQBpG?si=43a975945636412e Philippa Balazs is a Kent-based AuDHD therapist and advocate. She runs a thriving private practice “Flourish with Philippa” where she specialises in late diagnosis, high masking women, and supporting ND parents with ND kids. She is also training to be a ADHD Coach. Check out Philippa's links. Website - https://www.flourish-counselling.co.uk/ Linktree - https://linktr.ee/flourish_with_philippa Instagram - https://www.instagram.com/flourish_with_philippa/ Misophonia Article - https://www.autistictherapistdirectory.com/post/misophonia-when-everyday-sounds-feel-unbearable These conversations are not a substitute for professional medical or therapeutic support. Please seek support from professionals trained within Neurodiversity support. Listen to episodes with care. Keep up to date with our latest posts on Instagram. Thank you for supporting the show, Owen
What if marriage were approached as a business enterprise instead of an emotional pursuit? How can women quickly identify incompatible men? How can men find peace and clear communication with women? Today Adam Lane Smith and I discuss these and so many more questions as we explore how to have thriving relationships and marriages. Adam's Website: https://adamlanesmith.comNEW: Check out our Merch store! https://shop.lilaroseshow.com/Join our new Patreon community! https://patreon.com/lilaroseshow - We'll have BTS footage, ad-free episodes, and early access to our upcoming guests.A big thanks to our partner, EWTN, the world's leading Catholic network! Discover news, entertainment and more at https://www.ewtn.com/ Check out our Sponsors:-Good Ranchers: https://www.goodranchers.com/discount/LILA Purchase your American Meat Delivered subscription today and get a free add-on for life + Use code LILA for $25 off! -EveryLife: https://www.everylife.com/lila Buy diapers and women's health products from an amazing company and use code LILA to get 10% off!-We Heart Nutrition: https://www.weheartnutrition.com/ Get high quality vitamin supplements for 20% off using the code LILA. -Brave+: Screen Time Made Good - Get a week free trial at https://braveplus.com/lila00:03:17 - Intro00:03:47 - Marriage as Business00:10:36 - Stimulating vs Attracting 00:14:54 - Supermodels that feel ugly 00:19:33 - How men can find peace:00:21:21 - Why some men can't flirt with their wives00:22:28 - This 3 min convo can save your marriage00:28:19 - 4 Step Framework that can change everything00:32:49 - When men are afraid of asking for help00:37:15 - When men have male friends closer than wives00:41:35 - Is it possible to find this kind of man?00:43:29 - Women: probe men!00:44:01 - 3 Date Method00:50:33 - Ask more questions!00:52:33 - One thing I wish I could tell women00:55:06 - The Goal is Win/Win01:01:48 - Martyrdom Marriages are not to be pursued01:05:10 - The worst lie we tell married women01:06:18 - Consequences women can put on men01:09:43 - Should women withhold sex?01:12:59 - Divorce?01:16:34 - What about consequences for women?01:19:51 - Biggest mistakes women make?01:23:39 - What if he's a jerk?01:31:40 - Where women fall short01:34:04 - Is virginity reasonable expectation?01:40:49 - What advantages does Gen Z have?01:54:29 - Biggest transformation Adam has seen02:02:11 - Red Flags and Green Flags
Academically Challenging vs. Intellectually Stimulating - academically challenging is how most of school is set up, where things gets progressively more and more difficult. Intellectually stimulating is where students are challenged in their thinking. Which one is used more in school and how can we balance these?
The Full Go returns as Jason starts the pod by giving his thoughts on the NFL draft combine! He talks about the process as a whole and why Kenyon Sadiq and Sonny Styles stood out to him. Next, Jason and Kyle discuss the Blackhawks trading longtime defenseman Connor Murphy and talk about how long the Hawks' rebuild is taking. After that, Jason discusses why he's buying back into the White Sox before wrapping with his thoughts on Luke Kornet saying the Atlanta Hawks should end their collaboration with Magic City. The Ringer is committed to responsible gaming. Please visit www.rg-help.com to learn more about the resources and helplines available. Voicemail line: 708-550-3781 Host: Jason Goff Producer: Kyle Williams Learn more about your ad choices. Visit podcastchoices.com/adchoices
Vagus nerve stimulators are the trending new device for migraines. FDA-cleared, handheld, marketed as a breakthrough. Sounds promising, right? But if you're wondering whether adding one more device to your migraine toolkit will finally be the answer, or if it's just another expensive band-aid, this episode breaks down what you need to know. You'll learn what the vagus nerve actually does (it powers your entire digestive tract, heart, lungs, and all your internal organs), how these devices work by adding electrical voltage to the nerve, and why they help some people but not others. The truth is this: Stimulating the nerve without addressing the root cause is like putting a band-aid on a cut that keeps reopening. If you're looking for the one thing that will finally crack the case, these devices won't be it. But if you're ready to address all three principles and understand why your body lost its resilience in the first place, this episode will show you the bigger picture. If you're experiencing 8+ migraine days per month and ready to address the root cause instead of just managing symptoms, schedule a free consultation below: https://www.drlesliecisar.com/apply Free Training: 5 Proven Steps to Being Migraine Free (Even if you think you've already tried everything.) https://www.drlesliecisar.com/5SHMN Connect with us: Website: https://www.drlesliecisar.com/ Free Facebook Group: Healing Migraines Naturally, with Leslie Cisar, ND Ready to try something radically different that actually works? Read more about my approach here: https://www.drlesliecisar.com/map In health,Dr. Leslie Cisar
In this episode, we sit down with Sarah Kennedy, Founder and CEO of Calocurb, to explore a radically different approach to appetite control rooted in real science, not willpower. With decades of leadership in nutrition and food science, Sarah breaks down how GLP-1s work, the downsides of chronic calorie restriction, and the key differences between synthetic drugs like semaglutide and natural GLP-1 stimulation. We dive into the history of bitters, digestion, and how Calocurb's patented ingredient Amarasate® supports appetite regulation through the gut–brain axis. Sarah also shares compelling clinical trial results, insights on coming off GLP-1 drugs, and why under-eating—especially for women—can backfire hormonally. It's a nuanced, empowering conversation about working with your biology to feel satisfied, nourished, and in control.Founder and CEO of Calocurb, Sarah Kennedy shepherded years of scientific research and clinical trials to bring a revolutionary product to market. A veterinarian by training, with more than 20 years' experience in dietary and animal nutrition, Sarah has held a number of CEO and senior executive positions in food and agriculture industries, at companies including Fonterra and Healtheries/Vitaco NZ. In 2010, at MIT, Sarah completed a Sloan Fellowship Program in Global Leadership and Innovation and has spent decades leading in health, nutrition and consumer products with executive roles at many, many companies.Calocurb is a 100% natural appetite control supplement. Amarasate®, the patented active ingredient in Calocurb, was developed in New Zealand over 14 years and with $30m invested by Plant and Food Research, the largest NZ government-owned research institute.SHOW NOTES:0:40 Welcome to the show!2:39 About Sarah Kennedy3:54 Welcome her to the podcast!5:04 What is a GLP-1?7:27 Downside of calorie restriction8:52 Natural vs synthetic GLP-113:41 Coming off of GLP-1s14:56 Why it isn't just willpower18:07 History of bitters in the diet20:12 Stimulating digestion & appetite suppression23:22 Calocurb Study26:02 Semaglutide vs Calocurb29:45 Clinical trial results32:54 Calocurb & PMS34:10 Dosing Calocurb40:08 Our personal experiences43:37 Importance of protein intake46:41 Females that are under-eating54:52 Where to find Sarah & Calocurb55:30 Her final piece of advice57:21 Thanks for tuning in!RESOURCES:Website: www.Calocurb.com - Discount code: BIOHACKERBABESIG: CalocurbFacebook: CalocurbGLOBALSupport this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands
Today, we're diving into the often-overlooked but vital role that sex plays in our overall health. Did you know that maintaining an active sex life can actually be beneficial for both your body and mind? Let's explore some of the incredible health benefits that come with regular sexual activity.First up, let's discuss cardiovascular health. Engaging in sexual activity isn't just a pleasurable experience; it can also serve as a form of light exercise. In fact, numerous studies have shown that regular sexual activity is linked to reduced risks of heart disease and stroke. If you're looking for another reason to get intimate, consider this: sexual activity can help keep your heart strong.But it doesn't stop there—let's talk about the immune system. It turns out, those steamy sessions can boost your defenses. Research indicates that people who have sex once or twice a week tend to have higher levels of immunoglobulin A, an important antibody that helps ward off infections. This means that regular sexual activity could contribute to better immunity and fewer sick days. Who wouldn't want that?Become a supporter of this podcast: https://www.spreaker.com/podcast/lets-talk-sex-and-dating--5052038/support.
Imagine your perfect place: an environment that continuously motivates you with stimulating music, brilliant visuals, and words of encouragement as well as peace and silence for self-growth. Stay tuned for great tips on creating a stimulating environment for continuous Self-Growth and Success! The post Episode 197—Creating a Stimulating Environment for Growth appeared first on Endless Brain Energy.
Cosmic dust reveals a hidden history of past sea-ice – does it predict a crash of Arctic Ocean life? Stimulating new science with Dr. Frank Pavia, University of Washington. Then “The normalization of (almost) everything” with computational cognitive scientist Rachit Dubey.
Today I'm talking about stimulating your vagus nerve. You see if your vagus nerve has a high vagal tone, it can easily help you drop out of your chronic stress state into your rest and digest state. Whereas if your vagal tone is low, then it's a lot harder for you to be able to make that shift. But there are many ways that you can stimulate your, your vagus nerve in order to increase your vagal tone.About the Host:Melissa is an Integrative Health Practitioner helping people get to the root cause of their health issues. Melissa neither diagnoses nor cures but helps bring your body back into balance by helping discover your “toxic load” and then removing the toxins. Melissa offers functional medicine lab testing that helps you “see inside” to know exactly what is going on, and then provides a personalized wellness protocol using natural herbs and supplements. Melissa's business is 100% virtual –the lab tests are mailed directly to your home and she specializes in holding your hand and guiding the way to healing so that you don't have to figure it all out on your own. Melissa has been featured at a number of Health & Wellness Summits, such as the Health, Wealth & Wisdom Summit, The Power To Profit Summit, The Feel Fan-freaking-tas-tic Summit, and the Aim Higher Summit, and has guested on over 30 different podcasts teaching people about the importance of prioritizing our health and how to get get started. www.yourguidedhealthjourney.comLinkedIn: https://www.linkedin.com/in/melissadeally/FB: https://www.facebook.com/GuidedhealthjourneyInstagram: https://www.instagram.com/guidedhealthjourney/Thanks for listening!If you know somebody who would benefit from this message, or would be an awesome addition to our community, please share it using the social media buttons on this page. Do you have some feedback or questions about this episode? Leave a note in the comment section below!Subscribe to the podcast!If you would like to get automatic updates of new podcast episodes, you can subscribe to the podcast app on your mobile device.Leave us a review!We appreciate every bit of feedback to make this a value-adding part of your day. Ratings and reviews from our listeners not only help us improve, but also help others find us in their podcast app. If you have a minute, an honest review on Apple Podcasts/iTunes goes a long way! Thank You!!
The signs and symptoms we feel when our brain is impaired can be anything from headaches to mental health struggles to really any body function not operating well. The brain is our body's control center. Dr. Ali Elahi has studied for years to find ways to improve brain function quickly and without pharmaceuticals. He shares several techniques he uses including transcranial magnetic stimulation.Transcranial magnetic stimulation (TMS) is a significant technological breakthrough that is quickly replacing use of medications for non-pharmacological treatment of numerous neurological conditions including depression, anxiety, chronic pain, Parkinson's, and stroke.Dr. Ali Elahi, the founder of NeuroSpa Brain Rejuvenation Centers, is board-certified by the American Board of Psychiatry and Neurology (ABPN) and practicing neurology for nearly 20 years. Subscribe to his YouTube Channel @neurospabrain and follow on Instagram @neurospabrain. Visit ConfidenceThroughHealth.com to find discounts to some of our favorite products.Follow me via All In Health and Wellness on Facebook or Instagram.Find my books on Amazon: No More Sugar Coating: Finding Your Happiness in a Crowded World and Confidence Through Health: Live the Healthy Lifestyle God DesignedProduction credit: Social Media Cowboys
As a psychologist, Gloria's career has covered the lifespan, starting with working with preschoolers, mainly boys, because female teachers are more distressed by boys than girls. Throughout almost 50 years of private practice, she has worked with preschoolers, elementary-aged children, teens, adults, and couples. Her training in Emotion Focused Therapy and Internal Family Systems has been effective in helping each client heal from childhood injuries and learn to embrace their strengths. Her recent book, Read, Reflect, Respond: the 3 R's of Growth and Change is designed to help adults examine their histories and grow into the present. Stimulating essays are paired with guided questions and an opportunity to draw, scribble, and write genuine reactions to the printed words. In this way, each person is guided to uncover parts of themselves and their histories, leading to the opportunity to change and grow. Her book in process How Not To f$%! Up Being A Father, is a guide for fathers on raising boys that maintain access to the full range of emotions and experience a sense of competence about being able to express feelings. For centuries, we have raised boys to suppress access to the more tender range of feelings. Then we expect them to exhibit compassion, form deep commitments, get married, develop an intimate, supportive emotional relationship with another, and eventually provide emotional guidance to their sons and daughters. This is a setup for failure. One cannot lead down a path that they have never been allowed to walk.Learn more about Dr. Gloriahttps://drvanderhorst.com/Kelley Glenn's Artist Reception and Art Salehttps://www.eventbrite.com/e/artist-reception-art-sale-at-restaurant-198-resilience-collection-tickets-1934349965819?aff=oddtdtcreator@KindlyKelley https://www.instagram.com/kindlykelley/?hl=enMovemberhttps://movember.com/m/14654248?mc=1--Get in touch: robinsmithshow@gmail.comCall the hotline: +1 (301) 458-0883Follow Robin on Insight Timer: https://insighttimer.com/robinsmithBecome a supporter on Patreon: https://www.patreon.com/therobinsmithshowGot a question? We'd love to hear from you!
De'Ann Richter is a renowned coach at Breast Cancer Conqueror who works closely with Veronique Desaulniers. Their mission is to provide women and men with a variety of options when it comes to cancer, specifically breast cancer. New episodes of Welcome to Wellness released every Friday!Not listening on Spotify? Show notes at: https://www.ashleydeeley.com/w2w/breastcancerconquerorEpisode brought to you by: Alive Waters (Code: ASHLEY)Episode brought to you by: ARAZA BeautyEpisode brought to you by: VieLight (Code: DEELEYA25VL)3:23: Has been a coach for over 10 years4:23: The Seven Essentials8:15: Dr Veronique Desaulniers, two-time breast cancer survivor10:29: How to heal 12:16: Broccoli Sprouts & Sulforaphane supplement 12:42: Vitamin D 12:54: Curcumin 13:05: Modified Citrus Pectin / or, Econugenics brand of Modified Citrus Pectin powder13:35: Modified citrus pectin can up regulate the P53 gene which helps kill tumors14:40: Exposing your breasts to sunlight15:19: Stop wearing underwire bras16:33: Reduce your EMF exposure (Visit Tech Wellness to learn more!) 17:40: Gia for EMF protection (or BluShield is one of my favorites!)18:48: My free Clean Beauty Guide21:35: Thermography22:37: Inflammatory markers (ask for these on your blood test): 23:58: BRCA gene25:19: Difference between mammography and thermography28:04: Ultrasounds29:00: Diagnostic sample31:48: Coffee enemas (MUST use organic coffee) (blog post)34:03: You don't get glutathione from food36:46: Wine during cancer (low alcohol is OK! Dry Farm wine ONLY makes low alcohol wine!)38:26: Anatomy of an Illness38:44: Stimulating the vagal nerve42:31: How to mitigate damage from chemo42:41: Dr. Valter Longo: Fasting Cancer43:39: Mistletoe & breast cancer44:19: Sex, Lies, & Menopause45:27:* Morning Glory tincture45:44: *Dandelion tincture46:12: Bioidentical Hormone Replacement Therapy (hormone solutions)50:23: * DIM50:52: Soy & breast cancer (YES to Haelen, fermented soy beverage)56:05: Top book recommendations:Heal Breast Cancer Naturally The Metabolic Approach to CancerHow to Starve CancerYou Are the PlaceboGetting Well AgainThe Success PrinciplesLimitless by Jim KwikWhere to find De'Ann:WebsiteInstagramcoaching@breastcancerconqueror.comWhere to find Ashley Deeley:WebsiteInstagramFacebookYouTubehello@ashleydeeley.com
Kevin J. Tracey, MD is president and CEO of the Feinstein Institutes for Medical Research at Northwell Health, a pioneer of vagus nerve research and author of the recent book, The Great Nerve: The New Science of the Vagus Nerve and How to Harness Its Healing Reflexes. This episode is brought to you by:Eight Sleep Pod Cover 5 sleeping solution for dynamic cooling and heating: EightSleep.com/Tim (use code TIM to get $350 off your very own Pod 5 Ultra.)AG1 all-in-one nutritional supplement: https://DrinkAG1.com/Tim (1-year supply of Vitamin D plus 5 free AG1 travel packs with your first subscription purchase.)Wealthfront high-yield cash account: https://Wealthfront.com/Tim (Start earning 4.00% APY on your short-term cash until you're ready to invest. And when new clients open an account today, you can get an extra fifty-dollar bonus with a deposit of five hundred dollars or more.) Terms apply. Tim Ferriss receives cash compensation from Wealthfront Brokerage, LLC for advertising and holds a non-controlling equity interest in the corporate parent of Wealthfront Brokerage. See full disclosures here.Timestamps:00:00 Tim's intro: why he dismissed vagus-nerve hype06:34 What the vagus nerve actually is, plus common myths11:31 Breaking news: FDA approval for SetPoint's RA implant + Kelly Owens's turnaround21:11 Inflammation 101: when healing turns harmful31:37 Bioelectronic medicine: from lab insight to real devices55:26 TNF, IL-1, and IL-6: immune drivers and what VNS modulates56:06 Exercise & recovery: vagal signals, IL-6, and adaptation56:30 Cold exposure & breathwork: sympathetic spike, parasympathetic payoff59:04 Chronic inflammation today: prevalence, diagnostics, and uncertainty59:53 Autoimmunity: genes, environment, infections01:01:08 Stress hormones, personality traits, and metabolic fallout01:05:41 VNS tech landscape: implants, focused ultrasound, and what's just TENS01:11:14 Ear maps, revisited: the real science behind auricular stimulation01:27:52 Ulf Andersson: auricular TENS, famotidine, and a depression turnaround01:36:48 Depression & inflammation: where VNS helps (and where it doesn't)01:41:38 Body-brain loop: how inflammation signals ride the vagus nerve01:42:56 Why VNS can lift mood: a working theory01:43:22 Ulf's setup: electrode placement and twice-daily routine01:44:37 Acupuncture, fertility, and plausible vagal links01:47:23 Chronic pain through an inflammation lens01:48:34 Neural “engrams”: how the brain can store inflammatory memories02:02:35 Cervical TENS vs. true VNS: mechanisms and open questions02:12:15 On stage with the Dalai Lama: blue energy and two vagus nerves02:16:55 Closing thoughts: self-care vs. medical devices, and what's next*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissPast guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, Margaret Atwood, Mark Zuckerberg, Peter Thiel, Dr. Gabor Maté, Anne Lamott, Sarah Silverman, Dr. Andrew Huberman, and many more.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today, I'm talking about stimulating your vagus nerve. If your vagus nerve has a high vagal tone, it can easily help you drop out of your chronic stress state into your rest and digest state. About the Host:Melissa is an Integrative Health Practitioner and a Board Designated Trainer of NLP, Time Line Therapy®, Hypnotherarpy, and NLP Results Coaching, helping people get to the root cause of their health issues and then get lasting results. Melissa neither diagnoses nor cures but helps bring your body back into balance by helping discover your “toxic load” and then removing the toxins. Melissa offers functional medicine lab testing that helps you “see inside” to know exactly what is going on, and then provides a personalized wellness protocol using natural herbs and supplements. Melissa's business is 100% virtual – the lab tests are mailed directly to your home and she specializes in holding your hand and guiding the way to healing so that you don't have to figure it all out on your own.Melissa has launched Amplify Impact Academy, with business partner, Billie Aadmi and together they train other coaches, practitioners and counsellors in the 4 mind-body healing modalities mentioned above, giving them powerful tools to use with clients to get results with greater ease, speed and grace. These courses teach life skills and anyone can take them, if you wanto be a better leader, parent, partner, be empowered in your own life, these courses are for you!Melissa's passion project is her non-profit, Girls Matter (www.girlsmatter.ca), breaking the poverty cycle 1 girl, 1 family, 1 village at a time. The mission is to keep girls in school and stop teenage marriages, because school isn't free in over 50 countries around the world and when parents have to make the difficult choices of feeding their kids or paying for school, food wins. And when the girls hit their teen years, they will often be married off so that someone else becomes responsible to feed them. Keeping girls in school instead creates a generational ripple effect, because an educated girl is more than twice as likely to ensure her on children are educated. Educating girls also grows the GDP of countries, when they get into the workforce. This is how together, we can change the world. Guests on this podcast are invited to donate to this important cause. Learn more here in this short video: https://drive.google.com/file/d/1R3-xqzJLZW14om1PhFClcU_oRSZ8zgip/view?usp=share_linkMelissa is the winner of the 2024 Women in Podcasting Awards in the “inspiration & motivation” category and the 2021 & 2022 Quality Care Award by Business From The Heart and is also the recipient of the Alignable “Local Business Person of the Year “Award 2022, 2023 & 2024 for Whistler.Melissa has been featured at a number of Health & Wellness Summits, such as the Health, Wealth & Wisdom Summit, The Power To Profit Summit, The Feel Fan-freaking-tas-tic Summit, the Aim Higher Summit and many more! She has also guested on over 90 different podcasts teaching people about the importance of prioritizing our health and how to get started. Linktree: https://linktr.ee/yourguidedhealthjourney Thanks for listening!If you know somebody who would benefit from this message, or would be an awesome addition to our community, please share it using the social media buttons on this page.Do you have some feedback or...
Dr. Kevin J. Tracey, neurosurgeon, immunologist, and pioneer in bioelectronic medicine, discusses the discovery of the inflammatory reflex and how vagus nerve stimulation can precisely regulate immune activity without immunosuppression. He explains its clinical application in rheumatoid arthritis, potential use in Crohn's disease, multiple sclerosis, and metabolic disorders, and its implications for extending healthspan. Watch the full episode to explore how targeting neural circuits could redefine the treatment of inflammation. Learn more about Dr. Kevin J. Tracey: https://feinstein.northwell.edu/institutes-researchers/our-researchers/kevin-j-tracey-md - Download Dr. Buck Joffrey's FREE ebook, Living Longer for Busy People: https://ru01tne2.pages.infusionsoft.net/?affiliate=0 Book a FREE longevity coaching consultation with Dr. Buck Joffrey: https://coaching.longevityroadmap.com/
In this episode, Pat Light and Tevo discuss the importance of gratitude amidst busy lives, reflect on personal milestones, and share insights on the impact of social media on business. They explore the relationship between reality shows and bar sales, and delve into the drinking trends of Gen Z, questioning whether they are truly drinking less or if it's a financial decision. The conversation highlights the evolving nature of bars as social platforms and the challenges faced by business owners in adapting to changing consumer behaviors.Chapters00:00 Gratitude in Busy Times02:44 Navigating Business Hecticness05:35 Reflections on Legends Lost08:18 The Influence of Social Media10:59 Marketing Strategies and Insights27:26 Maximizing Revenue Through Marketing Strategies29:56 The Impact of Viral Marketing on Engagement31:22 Reality Shows as a Sales Driver for Bars36:40 Navigating the Challenges of Reality Show Promotions42:53 Gen Z's Drinking Habits and Bar Revenue DynamicsYouTube and Socialshttps://mtr.bio/sorry-were-closed-Pod
In this episode of Moonshots, hosts Mike and Mark delve into the fascinating realm of willpower, contrasting the philosophies and methodologies of two remarkable individuals: David Goggins and Andrew Huberman.Buy The Book on Amazon https://geni.us/neverfinishedBecome a Moonshot Member https://www.patreon.com/MoonshotsWatch this episode on YouTube https://youtu.be/P6s-7coWBrESummary 1: https://www.apolloadvisor.com/cant-hurt-me-david-goggins-book-summary/Summary 2: https://www.apolloadvisor.com/summary-never-finished-unshackle-your-mind-and-win-the-war-within-by-david-goggins/INTRO: A Conversation with David Goggins and Andrew HubermanIn the opening segment, hosts Mike and Mark facilitate a dynamic conversation between David Goggins and Andrew Huberman. Goggins shares his daily motivational journey, highlighting the transformative power of effort and passion. The discussion sets the tone for exploring the nuances of willpower and self-motivation.Clip 1: It's You Against YouDavid Goggins delivers unfiltered truths on personal accountability in this segment. He confronts listeners with the stark reality that the biggest obstacle to change often lies within oneself. Goggins's message serves as a wake-up call, urging individuals to take ownership of their actions and embrace the challenge of self-improvement head-on.Clip 2: Stimulating the 'Willpower' CortexAndrew Huberman enters the spotlight to dissect the science behind enhancing our 'willpower' cortex. He advocates for stepping outside comfort zones and engaging in activities that may not yield immediate gratification. Huberman's insights shed light on the neurological processes that strengthen our mental resilience, offering practical strategies for personal growth.OUTRO: Building Inner Strength Through PracticeAs the episode draws close, Andrew Huberman emphasizes the importance of consistent practice in building inner strength. He stresses that willpower is not a fixed trait but a skill that can be honed through dedicated effort. Huberman's concluding remarks serve as a poignant reminder of the transformative potential inherent in embracing the journey of continuous practice.In this enlightening episode of Moonshots, join Mike and Mark as they navigate the fascinating interplay between grit, determination, and neuroscience. Thanks to our monthly supporters Emily Rose Banks Malcolm Magee Natalie Triman Kaur Ryan N. Marco-Ken Möller Lars Bjørge Edward Rehfeldt III 孤鸿 月影 Fabian Jasper Verkaart Andy Pilara ola Austin Hammatt Zachary Phillips Mike Leigh Cooper Gayla Schiff Laura KE Krzysztof Roar Nikolay Ytre-Eide Stef Roger von Holdt venkata reddy Ingram Casey Ola rahul grover Ravi Govender Craig Lindsay Steve Woollard Lasse Brurok Deborah Spahr Barbara Samoela Jo Hatchard Kalman Cseh Berg De Bleecker Paul Acquaah MrBonjour Sid Liza Goetz Konnor Ah kuoi Marjan Modara Dietmar Baur Bob Nolley ★ Support this podcast on Patreon ★
Jason presents Travis King, CEO of Realm, a real estate investor collective, focusing on the "Big Beautiful Bill" and its positive implications for real estate investors. They discuss specific provisions like accelerated depreciation and the permanent grandfathering of Opportunity Zones, highlighting their role in attracting capital back into the market. They explore broader real estate trends, including interest rates, the "lock-in effect" on housing supply, and the importance of cost segregation for tax benefits. The conversation also touches on replacement costs, the inelasticity of housing supply, and the contrasting affordability dynamics in various markets, ultimately affirming a bullish outlook on real estate investment due to its unique tax advantages and tangible nature. https://www.realmlp.com/ #TravisKing, #BigBeautifulBill, #NationalAssociationOfRealtors, #RealEstateBoom, #AcceleratedDepreciation, #OpportunityZones, #TaxBenefits, #InvestmentLiquidity, #InterestRates, #MortgageRates, #LockInEffect, #HousingSupply, #HousingDemand, #HousingAffordability, #CostSegregation, #TaxAdvantages, #1031Exchange, #AcquisitionStrategy, #ReplacementCost, #ConstructionCosts, #RentGrowth, #SupplyAndDemand #YieldInvesting, #Capitulation, #DriveToQualify, #BullishOnRealEstate, #TaxLiability Key Takeaways: 1:48 Welcome Travis King 3:12 The Big Beautiful Bill and from an investment perspective 6:35 Mortgage rates and the "Lock-in Effect" 10:30 Bonus depreciation and cost segregation 12:49 Sponsor: https://www.monetary-metals.com/Hartman/ 14:48 Stimulating the market 17:59 Regression to Replacement cost and the Inelasticity of the housing market 21:29 Rents and the bottom of capitulation 27:54 Bullish on the housing market Follow Jason on TWITTER, INSTAGRAM & LINKEDIN Twitter.com/JasonHartmanROI Instagram.com/jasonhartman1/ Linkedin.com/in/jasonhartmaninvestor/ Call our Investment Counselors at: 1-800-HARTMAN (US) or visit: https://www.jasonhartman.com/ Free Class: Easily get up to $250,000 in funding for real estate, business or anything else: http://JasonHartman.com/Fund CYA Protect Your Assets, Save Taxes & Estate Planning: http://JasonHartman.com/Protect Get wholesale real estate deals for investment or build a great business – Free Course: https://www.jasonhartman.com/deals Special Offer from Ron LeGrand: https://JasonHartman.com/Ron Free Mini-Book on Pandemic Investing: https://www.PandemicInvesting.com
In this episode, Cathy Sykora is joined by Ani Papazyan, a Pain Resolution Practitioner with 30 years of experience helping people find relief through science-based techniques and personalized strategies. They discuss the crucial differences between acute and chronic pain, and why understanding this distinction is key to lasting recovery. Ani shares powerful self-help tools for stimulating the vagus nerve, relieving jaw tension, and reducing stress—often overlooked contributors to chronic pain. You'll also learn surprising connections between pain, brain function, and nutrition, including the impact of high-histamine foods on migraines and inflammation. In this episode, you'll discover: Why chronic pain requires a completely different approach than acute pain A daily vagus nerve stimulation technique that helps calm the nervous system The surprising connection between jaw tension and neck, back, and hip pain A step-by-step self-help exercise to release TMJ tension and promote relaxation How histamine-rich "healthy" foods can trigger migraines and chronic pain Natural alternatives to antihistamines, like berberine and wild oregano oil Why addressing stress is essential for effective pain resolution Memorable Quotes: "Your body is not like Amazon Prime. It's a process." "Chronic pain and acute pain are so different, and the approach to them should be completely different." "Stimulating your vagus nerve and calming your nervous system down—that's one of the best daily practices you can do." Bio: Ani Papazyan is a Pain Resolution Practitioner, best-selling author, and speaker with 30 years of experience. She holds a bachelor's degree in Kinesiology and certifications in medical massage therapy, functional nutrition, and advanced translational nutrigenomics. As the founder of Last Stop 4 Pain, Ani empowers individuals to achieve pain-free living through personalized strategies and education. She has worked with diverse clients, including professional athletes and Hollywood's Elite, helping them recover from injuries and stress. Ani is a sought-after expert in pain relief and wellness, dedicated to guiding others toward their health goals. Mentioned in This Episode: Ani's 5 Body Pain Hacks: 5BodyPainHacks.com Links to Resources: Health Coach Group Website: thehealthcoachgroup.com Special Offer: Use code HCC50 to save $50 on the Health Coach Group website Leave a Review: If you enjoyed the podcast, please consider leaving a five-star rating or review on Apple Podcasts.
We try to figure out why Mr. Banks eats grass.
In this CME podcast episode, Dr. Andrew Cutler interviews Dr. Phillip Coffin, Director of the Center on Substance Use and Health in San Francisco, CA, about the management of stimulant use disorders. They explore the challenges of treatment and highlight the importance of harm reduction strategies to enhance patients' quality of life. CME credit is available to NEI Members only. Target Audience: This activity has been developed for the healthcare team or individual prescriber specializing in mental health. All other healthcare team members interested in psychopharmacology are welcome for advanced study. Learning Objectives: After completing this educational activity, you should be better able to: Summarize pharmacologic and behavioral treatment strategies for stimulant use disorders, particularly methamphetamine and cocaine Evaluate the evidence base for current and investigational medications used in clinical trials and real-world settings Apply harm reduction principles and integrated care models to improve outcomes for patients with stimulant use disorders in diverse clinical settings Accreditation: In support of improving patient care, this activity has been planned and implemented by HMP Education and Neuroscience Education Institute (NEI). HMP Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team. Activity Overview: This activity is available with synchronized audio and is best supported via a computer or device with current versions of the following browsers: Mozilla Firefox, Google Chrome, or Safari. A PDF reader is required for print publications. A post-test score of 70% or higher is required to receive CME/CE credit. Estimated Time to Complete: 1 hour Released: June 18, 2025* Expiration: June 17, 2028 *NEI and HMP Education maintain a record of participation for six (6) years. CME/CE Credits and Certificate Instructions: After listening to the podcast, to take the optional posttest and receive CME/CE credit, click: https://nei.global/POD25-02. Credit Designations: The following are being offered for this activity: Physician: ACCME AMA PRA Category 1 Credits™ HMP Education designates this enduring material for a maximum of 1.00 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Nurse: ANCC contact hours This continuing nursing education activity awards 1.00 contact hour. Provider approved by the California Board of Registered Nursing, Provider #18006 for 1.00 contact hour. Nurse Practitioner: ACCME AMA PRA Category 1 Credit™ American Academy of Nurse Practitioners National Certification Program accepts AMA PRA Category 1 Credits™ from organizations accredited by the ACCME. The content in this activity pertaining to pharmacology is worth 1.00 continuing education hour of pharmacotherapeutics. Pharmacy: ACPE application-based contact hours This internet enduring, knowledge-based activity has been approved for a maximum of 1.00 contact hour (.10 CEU). The official record of credit will be in the CPE Monitor system. Following ACPE Policy, NEI and HMP Education must transmit your claim to CPE Monitor within 60 days from the date you complete this CPE activity and are unable to report your claimed credit after this 60-day period. Ensure your profile includes your DOB and NABP ID. Physician Associate/Assistant: AAPA Category 1 CME credits HMP Education has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credits for activities planned in accordance with the AAPA CME Criteria. This internet enduring activity is designated for 1.00 AAPA Category 1 credit. Approval is valid until June 17, 2028. PAs should only claim credit commensurate with the extent of their participation. Psychology: APA CE credits Continuing Education (CE) credits for psychologists are provided through the co-sponsorship of the American Psychological Association (APA) Office of Continuing Education in Psychology (CEP). The APA CEP Office maintains responsibility for the content of the programs. This activity awards 1.00 CE Credit. Social Work: ASWB-ACE CE credits As a Jointly Accredited Organization, HMP Education is approved to offer social work continuing education by the Association of Social Work Boards (ASWB) Approved Continuing Education (ACE) program. Organizations, not individual courses, are approved under this program. Regulatory boards are the final authority on courses accepted for continuing education credit. Social workers completing this internet enduring course receive 1.00 general continuing education credit. Non-Physician Member of the Healthcare Team: Certificate of Participation HMP Education awards hours of participation (consistent with the designated number of AMA PRA Category 1 Credit™) to a participant who successfully completes this educational activity. Peer Review: The content was peer-reviewed by an MD, LFAPA specializing in psychiatry, forensic, addiction to ensure the scientific accuracy and medical relevance of information presented and its independence from commercial bias. NEI and HMP Education takes responsibility for the content, quality, and scientific integrity of this CME/CE activity. Disclosures: All individuals in a position to influence or control content are required to disclose any relevant financial relationships. Any relevant financial relationships were mitigated prior to the activity being planned, developed, or presented. Disclosures are from the original live presentation, unless otherwise noted. Faculty Author / Presenter Andrew J. Cutler, MD Clinical Associate Professor, Department of Psychiatry and Behavioral Sciences, Norton College of Medicine, State University of New York Upstate Medical University, Syracuse, NY Chief Medical Officer, Neuroscience Education Institute, Malvern, PA Consultant/Advisor: AbbVie, Acadia, Alfasigma, Alkermes, Axsome, Biogen, BioXcel, Boehringer Ingelheim, Brii Biosciences, Cerevel, Corium, Delpor, Evolution Research, Idorsia, Intra-Cellular, Ironshore, Janssen, Jazz, Karuna, Lundbeck, LivaNova, Luye, MapLight Therapeutics, Neumora, Neurocrine, NeuroSigma, Noven, Otsuka, Relmada, Reviva, Sage Therapeutics, Sumitomo (Sunovion), Supernus, Takeda, Teva, Tris Pharma, VistaGen Therapeutics Speakers Bureau: AbbVie, Acadia, Alfasigma, Alkermes, Axsome, BioXcel, Corium, Idorsia, Intra-Cellular, Ironshore, Janssen, Lundbeck, Neurocrine, Noven, Otsuka, Sumitomot (Sunovion), Supernus, Takeda, Teva, Tris Pharma, Vanda Data Safety Monitoring Board (DSMB): COMPASS Pathways, Freedom Biosciences Faculty Author / Presenter Phillip Coffin, MD, MIA Director of Center on Substance Use and Health, San Francisco Department of Public Health, San Francisco, CA No financial relationships to disclose. 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Episode 219: Unlocking the Power of S.M.A.R.T. Work DesignIn this episode, Dr. Janel Anderson introduces the SMART Work Design model, a research-backed framework created by organizational psychologist Sharon Parker. She breaks down the acronym—Stimulating, Mastery, Agency, Relational, and Tolerable demands—showing how each component contributes to motivating, sustainable, and human-centered work. Through practical examples, including a window washer's job, Dr. Anderson illustrates how the SMART model can be applied to any role. Whether you're leading teams or evaluating your own workflow, this episode offers actionable strategies for improving engagement, well-being, and productivity by rethinking how work is structured—not just managed.Find show notes at https://janelanderson.com/219
Today's guest is Dr. Chet Moritz. Chet is the CJ and Elizabeth Hwang endowed professor in the departments Electrical and Computer Engineering, Rehabilitation Medicine and Neurobiology & Biophysics at the University of Washington (UW) in Seattle. He also serves as the Co-director for the Center for Neurotechnology. Chet's work in Transcutaneous Spinal Stimulation (TSS) heavily contributed to the Onward Medical Arc-EX device which recently gained FDA approval. More info: https://u2fp.org/get-educated/curecast/episode-123.html
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There are moments when sitting down to do something meaningful feels physically uncomfortable, like your brain is actively protesting. You open your laptop with the best intentions, and five minutes later, you're in a black hole of browser tabs, group chats, and a suspicious number of snack breaks. Why is it so hard to focus, especially on the stuff that actually matters? In this episode, I unpack the science behind that resistance, why our brains crave distraction, how dopamine has hijacked our motivation system, and why chasing pleasure might be the exact thing pulling us away from purpose.For more go to: www.scottmlynch.comLevel up your life by joining my Patreon where you'll get exclusive content every week and more badass offerings (rips t-shirt in half, Hulk Hogan style, and runs around the room). And/or…Unlock practical and tactical insights on how to master your mindset and optimize your happiness directly to your inbox.If you're a glutton for punishment and want more swift kicks in the mind follow me on social:InstagramYouTubeLeave a review and tell me how I suck so I can stop doing that or you can also tell me about things you like. I'd be okay with that, too.Produced by ya boi.Past guests on The Motivated Mind include Chris Voss, Captain Sandy, Dr. Chris Palmer, Joey Thurman, Jason Harris, Koshin Paley Ellison, Rudy Mawer, Molly Fletcher, Kristen Butler, Hasard Lee, Natasha Graziano, David Hauser, Cheryl Hunter, Michael Brandt, Heather Moyse, Tim Shriver, and Alan Stein, Jr.
Send us a textIn this episode of The Wall Street Skinny, Kristen and Jen kick announce the launch of their long-awaited M&A course, part of their dynamic, story-driven finance curriculum. They discuss how the course, two years in the making, blends real-world technicals with the drama of HBO's Succession, making complex M&A concepts like accretion/dilution, deferred taxes, and tax structuring both engaging and accessible. They also announce a major May SALE on their self-paced course, see the links below to participate!From there, the conversation dives deep into the latest market headlines. Jen unpacks the recent Fed meeting, clarifying misconceptions about quantitative easing and explaining how the Fed is managing its shrinking balance sheet through non-competitive treasury purchases. They also discuss how these moves tie into broader concerns about stagflation, market liquidity, and the mechanics behind treasury auctions—demystifying some of the viral finance content floating around online.Finally, they pivot to the major private equity news of the week: 3G Capital's $9.3 billion bid to take Skechers private. Kristen and Jen break down why companies often seek the shelter of private ownership during times of market turmoil, the structure of 3G's offer (including rollover equity options for shareholders), and what this signals for the broader M&A environment. Shop the MAY SALE:- Buy the FULL IBD / PE course for 20% off HERE- M&A Standalone Course $50 OFF HEREEnroll in the Financial Modeling Talent Accelerator Sign up for our Talent Accelerator HERE today! Visit Vanta.com/wallstreet for $1,000 off Start your FREE TRIAL of Training The Street's Turbo Macros HEREShop the MAY SALE:- Buy the FULL IBD / PE course for 20% off HERE- M&A Standalone Course $50 OFF HERE Enroll in the Financial Modeling Talent Accelerator HERE Join the Fixed Income Sales and Trading waitlist HERE Our content is for informational purposes only. You should not construe any such information or other material as legal, tax, investment, financial, or other advice.Public Disclosure: All investing involves the risk of loss, including loss of principal. Brokerage services for US-listed, registered securities, options and bonds in a self-directed account are offered by Public Investing, Inc., member FINRA & SIPC. Public Investing offers a High-Yield Cash Account where funds from this account are automatically deposited into partner banks where they earn interest and are eligible for FDIC insurance; Public Investing is not a bank. Cryptocurrency trading services are offered by Bakkt Crypto Solutions, LLC (NMLS ID 1890144), which is licensed to engage in virtual currency business activity by the NYSDFS... ...
Are stimulating foot orthoses all hype or actually helpful for balance? Join @dustinjones.dpt as he discusses what you need to know about this new study looking at the impact of stimulating foot orthoses on balance in older adults. Referenced article (closed-access): https://doi.org/10.1016/j.gaitpost.2025.03.016 ----- Check out more info from the Older Adult Division and our Certification at https://PTonICE.com
Dr. Dustin Jones // #GeriOnICE // www.ptonice.com
My guest this week is author and architect Robert Raasch, whose recent debut novel The Summer Between is a coming-of-age adventure set in Greenwich Village of the late 1970s. It's a topic that Robert knows well, having lived through that time himself — making the most of the thrilling disco and loft parties and sexual exploration it had to offer. And now his book offers a glimpse back at the best of those years, and maybe some inspiration for recapturing that energy of liberation.We'll have that conversation in a minute. First, if you're enjoying The Sewers of Paris, I hope you'll consider supporting the show on Patreon. You may also enjoy my YouTube videos about the making of iconic movies and TV shows. And check out my weekly livestreams on Twitch, my book Hi Honey, I'm Homo!, and my free email newsletter. There's links to all that in the episode shownotes, and at MattBaume.com.
As we gain a better understanding of how misfiring brain circuits lead to mental health conditions, we'd like to be able to go in and nudge those circuits back into balance. But this is hard — literally — because the brain is encased in this thick bony skull. Plus, often the problem you want to target is buried deep in the middle of a maze of delicate brain tissue you need to preserve.Today we're going to be talking with neuroscientists who aim to solve this problem with sound. And not just any sound: ultrasound.Kim Butts Pauly and Raag Airan from the Stanford Department of Radiology are developing ultrasound technology in a couple of different ways to essentially reach into the brain to treat brain disorders that are otherwise hard to access. These uses of ultrasound haven't yet reached the clinic, but could be entering clinical testing in people in the next few years. Mentioned on the ShowMeet the 2025 Neurosciences Postdoctoral Scholars (Wu Tsai Neuro, 2025)Butts Pauly LabAiran LabNon-invasive brain stimulation opens new ways to study and treat the brain (Wu Tsai Neuro, 2025)Advancing Brain Resilience: 2024 Catalyst and Pilot Grant Awards (Knight Initiative for Brain Resilience, 2024)Researchers find response to ketamine depends on opioid pathways, but varies by sex (Stanford Medicine)A New Focused Ultrasound Neuromodulation System for Preclinical Brain Research (Focused Ultrasound Foundation, 2024)Translating Neuroscience Advances into Real World Uses (Wu Tsai Neuro, 2023)Get in touchWe want to hear from your neurons! Email us at at neuronspodcast@stanford.edu if you'd be willing to help out with some listener research, and we'll be in touch with some follow-up questions.Episode CreditsThis episode was produced by Michael Osborne at 14th Street Studios, with production assistance by Morgan Honaker. Our logo is by Aimee Garza. The show is hosted by Nicholas Weiler at Stanford's Wu Tsai Neurosciences Institute and supported in part by the Knight Initiative for Brain Resilience at Wu Tsai NeuSend us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.
In this episode, we sit down with Sarah Turner, CEO and co-founder of CeraThrive, to dive into the incredible benefits of red light therapy for both gut and brain health. Sarah shares her expertise on how red light therapy can support the body's natural healing processes and improve the health of the gut-brain axis. We explore the science behind this cutting-edge therapy, how it enhances cellular health, and practical tips for incorporating the CeraThrive into your daily routine. Whether you're looking to optimize gut health, support brain function, or boost overall well-being, this episode offers valuable insights into the healing power of light!Sarah Turner is an accomplished professional with an impressive educational background. She holds a postgraduate degree in Clinical Neuroscience from Roehampton University, London, and has earned BSc degrees in Psychological Sciences and Nutritional Medicine from Westminster University and Thames Valley University, respectively. Recently, she completed her diploma in PBM (Photobiomodulation) from Montpellier University, where she will particpate on the neurology module for the upcoming academic year. Sarah is the CEO and Co-Founder of the neurotech company, CeraThrive LLC - and the co-host of Rebel Scientist podcast.SHOW NOTES:0:39 Welcome to the podcast!2:31 Sarah Turner's bio3:13 Welcome Sarah to the show!4:15 Her background as a Neuroscientist5:22 Studying Parkinson's with Light8:18 Understanding the Gut-Brain Axis11:25 Symptoms of gut-brain dysfunction14:31 Why is there more mental health dysfunction?16:30 The evolution of light in our modern world20:32 Optimal wavelengths for healing26:35 All about the CeraThrive device!31:40 Low-level stress & antioxidants35:55 Stimulating the vagus nerve through the gut38:35 Why sleep requires energy40:58 Can red light override blue light exposure?44:37 Aligning your day with red light stacks49:37 Structured water for gut-brain health53:20 Recovering from Jet Lag55:00 How CeraThrive differs from other red light panels1:01:23 Where to find Sarah & CeraThrive1:02:41 Her final piece of advice1:04:45 Thanks for tuning in!RESOURCES:Website: CeraThrive - code: BIOHACKERBABES20IG: @CeraThriveLinkedIn: CeraThrive35 Best Biohacking PodcastsOur Sponsors:* Check out Effecty and use my code BIOHACKERBABES for a great deal: https://www.effecty.com* Check out Puori: https://puori.com/BIOHACKERBABESSupport this podcast at — https://redcircle.com/biohacker-babes-podcast/donationsAdvertising Inquiries: https://redcircle.com/brands
Discover the hidden pleasure zone that will revolutionize your intimate experiences and take her satisfaction to new heights! If you are a man who wants to elevate your sexual knowledge and skills, you will learn about vestibular bulbs, how to properly stimulate this overlooked erogenous zone. Learn why most women have never experienced the full potential of this erectile tissue and discover three game-changing techniques to incorporate this knowledge into your intimate encounters. Whether you are in a committed relationship or dating someone new, this episode has insight for you. The difference between good sex and mind-blowing sex isn't technique – it's understanding the full landscape of her pleasure anatomy.
How can you distinguish between actual health hacks and fake health trends? In this podcast, I'm going to tell you about ten health hacks that don't work and often cause more harm than good. Avoid these health hacks to save your health and your wallet! 1. Ear candling This treatment has been debunked by a doctor of audiology! There is absolutely no difference in ear wax before and after ear candling. 2. Gallbladder flush This almost killed me! A gallbladder flush involves drinking 12 ounces of olive oil followed by beet tablets to eliminate gallstones. This really eliminates bile, causing you to become deficient. TUDCA is a much better remedy to help prevent and eliminate gallstones and bile sludge. 3. The master cleanse This cleanse combines lemon juice, cayenne pepper, and maple syrup, which won't cleanse your body but will mess with your blood sugar. 4. Foot detox pads You can not pull toxins and heavy metals out of your feet as there are no detox pathways through the skin. 5. Foot detox bath Similar to foot detox pads, a chemical reaction changes the water's color during a foot detox bath, leading you to believe it's pulling toxins out of your body. 6. Ab belts Stimulating the stomach muscles or sweating will not remove fat from your midsection. Visceral fat must be removed through diet and exercise. 7. The blood type diet This diet is not supported by credible research. Blood types relate more to an immune difference rather than a digestive difference. 8. EMF blockers A sticker on your cell phone can not block the EMF radiation it omits. 9. Carb blockers Carb blockers contain an extract that can inhibit the digestion of a minimal amount of starch, not sugar. You would need to take several bottles to inhibit the digestion of the starch from one donut. 10. Psychiatric medication The effectiveness of psychiatric medication can be comparable to placebo outcomes. They may also come with serious side effects and can be highly addictive.
“For the earnest expectation of the creature waiteth for the manifestation of the sons of God....Because the creature itself also shall be delivered from the bondage of corruption into the glorious liberty of the children of God. For we know that the whole creation gr... More...
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In today's episode, Gina offers listeners a mini first aid kit for panic attacks and high stress anxiety moments. A number of steps are provided for neutralizing a panic attack in the early stages, before it gets out of control. Listen in for advice on how to better handle and diffuse panic attacks. Please visit our Sponsor Page to find all the links and codes for our awesome sponsors! https://www.theanxietycoachespodcast.com/sponsors/ Thank you for supporting The Anxiety Coaches Podcast. FREE MUST-HAVE RESOURCE FOR Calming Your Anxious Mind 10-Minute Body-Scan Meditation for Anxiety Anxiety Coaches Podcast Group Coaching link ACPGroupCoaching.com To learn more, go to: Website https://www.theanxietycoachespodcast.com Join our Group Coaching Full or Mini Membership Program Learn more about our One-on-One Coaching What is anxiety? Find even more peace and calm with our Supercast premium access membership: For $5 a month, all episodes are ad-free! https://anxietycoaches.supercast.com/ Here's what's included for $5/month: ❤ New Ad-Free episodes every Sunday and Wednesday ❤ Access to the entire Ad-free back-catalog with over 600 episodes ❤ Premium meditations recorded with you in mind ❤ And more fun surprises along the way! All this in your favorite podcast app! Quote: Everything you need you already have; you are complete right now. You are a whole total person, not an apprentice person on the way to someplace else. Your completeness must be understood by you and experienced in your thoughts as your own personal reality. –Wayne Dyer Chapters 0:04 Introduction to Panic Management 4:45 Understanding Panic Triggers 9:12 First Aid for Panic Attacks 11:41 Stimulating the Parasympathetic Nervous System 13:36 The Importance of Slowing Down 15:30 Conclusion and Encouragement Summary In today's episode of the Anxiety Coaches Podcast, I delve into the critical topic of managing panic attacks, offering listeners an essential first aid kit for navigating these overwhelming experiences. Panic attacks can strike unexpectedly, leaving individuals grappling with intense fear and the urgent need to escape their current environment. Throughout our discussion, I share personal anecdotes, reflecting on my own experiences with panic attacks and the feelings of dread that can envelop an otherwise normal day. We explore what happens during a panic attack, emphasizing the physiological responses that can be misinterpreted as imminent danger. Recognizing that these feelings do not equate to actual threat is paramount in managing them effectively. I stress the importance of acknowledging the panic attack for what it is, rather than succumbing to a cascade of fearful thoughts. Riding out the wave of panic, allowing it to ebb without fighting it, is a powerful technique I encourage listeners to practice. The conversation then expands to practical strategies to mitigate panic when it arises. I outline four key components for an effective first aid kit: understanding the situation, exercising wise thought to counter fear, stimulating the parasympathetic nervous system, and embracing mindfulness. We highlight the importance of self-talk during panic moments, urging listeners to remind themselves that they are safe, and the situation will eventually pass. I explain how this cognitive awareness can significantly reduce the overwhelming impact of panic. #PanicAttacks, #StressManagement, #AnxietyRelief, #CalmMind, #MentalHealth, #RelaxationTechniques, #PanicAttackFirstAid, #AnxietyRecovery, #CopingStrategies, #ParasympatheticNervousSystem, #Mindfulness, #BreathingExercises, #PanicPrevention, #MentalWellness, #SelfCare, #StressReduction, #Healing, #CalmingMusic, #BuddhaBellyBreathing, #OvercomingFear Learn more about your ad choices. Visit megaphone.fm/adchoicesSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In today's episode, Gina offers listeners a mini first aid kit for panic attacks and high stress anxiety moments. A number of steps are provided for neutralizing a panic attack in the early stages, before it gets out of control. Listen in for advice on how to better handle and diffuse panic attacks. Please visit our Sponsor Page to find all the links and codes for our awesome sponsors! https://www.theanxietycoachespodcast.com/sponsors/ Thank you for supporting The Anxiety Coaches Podcast. FREE MUST-HAVE RESOURCE FOR Calming Your Anxious Mind 10-Minute Body-Scan Meditation for Anxiety Anxiety Coaches Podcast Group Coaching link ACPGroupCoaching.com To learn more, go to: Website https://www.theanxietycoachespodcast.com Join our Group Coaching Full or Mini Membership Program Learn more about our One-on-One Coaching What is anxiety? Find even more peace and calm with our Supercast premium access membership: For $5 a month, all episodes are ad-free! https://anxietycoaches.supercast.com/ Here's what's included for $5/month: ❤ New Ad-Free episodes every Sunday and Wednesday ❤ Access to the entire Ad-free back-catalog with over 600 episodes ❤ Premium meditations recorded with you in mind ❤ And more fun surprises along the way! All this in your favorite podcast app! Quote: Everything you need you already have; you are complete right now. You are a whole total person, not an apprentice person on the way to someplace else. Your completeness must be understood by you and experienced in your thoughts as your own personal reality. –Wayne Dyer Chapters 0:04 Introduction to Panic Management 4:45 Understanding Panic Triggers 9:12 First Aid for Panic Attacks 11:41 Stimulating the Parasympathetic Nervous System 13:36 The Importance of Slowing Down 15:30 Conclusion and Encouragement Summary In today's episode of the Anxiety Coaches Podcast, I delve into the critical topic of managing panic attacks, offering listeners an essential first aid kit for navigating these overwhelming experiences. Panic attacks can strike unexpectedly, leaving individuals grappling with intense fear and the urgent need to escape their current environment. Throughout our discussion, I share personal anecdotes, reflecting on my own experiences with panic attacks and the feelings of dread that can envelop an otherwise normal day. We explore what happens during a panic attack, emphasizing the physiological responses that can be misinterpreted as imminent danger. Recognizing that these feelings do not equate to actual threat is paramount in managing them effectively. I stress the importance of acknowledging the panic attack for what it is, rather than succumbing to a cascade of fearful thoughts. Riding out the wave of panic, allowing it to ebb without fighting it, is a powerful technique I encourage listeners to practice. The conversation then expands to practical strategies to mitigate panic when it arises. I outline four key components for an effective first aid kit: understanding the situation, exercising wise thought to counter fear, stimulating the parasympathetic nervous system, and embracing mindfulness. We highlight the importance of self-talk during panic moments, urging listeners to remind themselves that they are safe, and the situation will eventually pass. I explain how this cognitive awareness can significantly reduce the overwhelming impact of panic. #PanicAttacks, #StressManagement, #AnxietyRelief, #CalmMind, #MentalHealth, #RelaxationTechniques, #PanicAttackFirstAid, #AnxietyRecovery, #CopingStrategies, #ParasympatheticNervousSystem, #Mindfulness, #BreathingExercises, #PanicPrevention, #MentalWellness, #SelfCare, #StressReduction, #Healing, #CalmingMusic, #BuddhaBellyBreathing, #OvercomingFear Learn more about your ad choices. Visit megaphone.fm/adchoices
A stem cell is a reserve cell that can become any cell you need. Stem cell research has shown positive results for people with fibrosis of the heart, liver fibrosis, and damaged brain cells. Stem cells can also be beneficial for the following: •Stimulating new cartilage in the joints •Autoimmune conditions •Rejuvenating skin cells •Cancer Here's how to keep your stem cell population at the highest level. 1. Fasting Prolonged fasting can boost stem cells naturally. If you can fast for 72 hours, you can boost stem cell production primarily for the gastrointestinal tract, brain, and immune system. 2. Exercise Intense exercise is the best way to boost stem cells for your muscles and brain. Exercise also stimulates BDNF (brain-derived neurotrophic factor), which allows you to make new nerve and brain cells. 3. Deep sleep Sleep increases melatonin, which stimulates stem cell regeneration in your brain. Sleep also increases immune and cardiovascular stem cells. 4. Green tea Green tea contains the phytonutrient EGCG, which has potent anti-inflammatory properties and can increase stem cells for your brain and liver. 5. Omega-3 fatty acids Decreasing inflammation can boost stem cell production. Omega-3 fatty acids are anti-inflammatory and can increase stem cells for your bones, cartilage, brain, and skin. 6. Vitamin D Vitamin D and the sun help maintain blood stem cells that are involved with the immune system. Vitamin D increases new immune cells, prevents the exhaustion of stem cells, and can even increase longevity. 7. Cold therapy The cold stimulates brown fat stem cells, which support muscle repair and the mitochondria, decrease inflammation, and increase blood flow. Barriers to stem cell production include: •Inflammation •Stress •Lack of sleep •Junk food •Alcohol •Smoking •Pollution Our normal cells have at least 50 genes that help cope with dehydration. Cancer cells have none of these genes. This is why dry fasting may be destructive to cancer cells.
In this episode, Dr. G sits down with Dave Asprey to explore the profound impact of nervous system regulation on overall health, diving into the connection between cellular biology and energy production. Together, they unpack modern health challenges, from the controversial history of seed oils to the effects of mineral deficiencies, the role of mitochondria, and how trauma can disrupt energy levels. Dave shares insights on biohacking and optimal recovery, including how air quality, balanced diets, and mold exposure influence well-being. Discover the science behind fasting, emotional wellness, and the essentials of maintaining resilient energy through daily practices. === Thank You To Our Sponsors! SiPhox Health Visit siphoxhealth.com/healthyself to get 20% off your first at-home blood test and start your journey toward optimal health. AirDoctor Visit https://airdoctorpro.com and use code DRG for 20% off Cornbread Hemp Visit cornbreadhemp.com/drg and use code DRG for 30% off your first order! === Show Notes: 00:00:00 - Introduction and Background on Dave's Career 00:01:11 - The Relationship Between Cell Biology and Nervous System 00:02:30 - Techniques for Nervous System Regulation 00:03:14 - Creating More Electricity in the Body 00:04:32 - Discussion on Seed Oils and Their Impact 00:05:56 - Historical Context of Seed Oils Controversy 00:07:34 - Teaching Kids About Healthy Eating 00:08:21 - Cell Membrane Flexibility and Insulin Resistance 00:09:44 - Mitochondrial Dysfunction and Aging 00:10:15 - Understanding Energy Production and the Nervous System 00:10:34 - Mitochondria as Environmental Sensors 00:11:05 - The Impact of Trauma on Energy Levels 00:13:18 - Techniques for Calming and Stimulating the Nervous System 00:18:01 - Discusses Mineral Deficiencies in Modern Diets 00:19:39 - Importance of Fat-Soluble Vitamins and Minerals for Bone Health 00:20:13 - Bone Surgery Experience 00:20:59 - Introduction to Danger Coffee and Minerals 00:21:45 - Importance of Electrolytes and Mineral Balance 00:24:13 - The Role of Animal Protein in Nutrition 00:26:44 - Overview of Upgrade Labs and Biohacking 00:28:46 - The Importance of Recovery in Fitness 00:30:00 - Benefits of Technology in Health and Wellness 00:30:15 - Commitment to Weight Loss Journey 00:30:32 - Injury and the Impact of Malnutrition 00:30:48 - Exploring Emotional Components of Weight 00:31:13 - Misconceptions About Eating Frequency 00:32:40 - Risks of Over Fasting and Its Effects 00:33:05 - Decline in Sleep Quality from Over Fasting 00:33:36 - Consequences of Nutrient Deficiencies 00:34:20 - Importance of Mitochondrial Health 00:34:52 - Resilience and Energy in Daily Life 00:37:57 - Mold Toxins and Weight Gain 00:38:58 - Mold's Role in Anxiety and Health Issues 00:39:31 - Importance of Air Quality in Health 00:41:38 - The Benefits of Danger Coffee 00:42:06 - Personal Experiences with Coffee and Jitters 00:42:13 - Introduction to Regulating the Nervous System 00:44:30 - The Biological Imperatives: Fear, Food, and Fertility 00:46:25 - The Importance of Friendship and Forgiveness 00:49:43 - The Connection Between Community and Nervous System Health 00:49:58 - Introduction to Mitochondrial Function and Beauty in Nature 00:51:23 - Techniques for Forgiveness and Personal Growth 00:52:06 - The Importance of Letting Go and Emotional Skills 00:52:17 - Discussion on Upcoming Book: Heavily Meditated 00:53:01 - Journey to Discover Clean Coffee 00:54:17 - How to Connect with Dave Asprey
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