Chemical substance that blocks the neurotransmitter acetylcholine in the central and the peripheral nervous system
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Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Meclizine is classified as a first-generation antihistamine. I discuss meclizine pharmacology, adverse effects, drug interactions, and much more. Meclizine is included on the Beers list due to its highly anticholinergic activity. Anticholinergic effects include constipation, dry eyes, dry mouth, urinary retention, and confusion. Sedation is an important adverse effect of meclizine. This adverse effect can be increased when used with other sedating medications such as opioids and benzodiazepines. Meclizine is primarily used for vertigo and motion sickness in clinical practice. The usual starting dose ranges between 12.5 to 25 mg. Meclizine is partially broken down by CYP2D6 so medications like bupropion can inhibit the breakdown of meclizine and lead to higher concentrations.
Dr. Valentina Mancini (Oxford University) joins AJP Audio to discuss the impact of anticholinergic burden on cognition in patients with schizophrenia. Afterwards, AJP Editor-in-Chief Dr. Ned Kalin puts the rest of the March issue into context. 00:32 Mancini interview 02:26 Anticholinergic burden method of action 02:58 Balancing the impact of side effects in schizophrenia treatment 04:52 Limitations 05:34 The need for further studies 05:59 Clinical implications 06:32 Further research 07:01 Trials needed 07:54 Kalin interview 08:03 Mancini et al. 11:23 Tiihonen et al. 13:43 Zhou et al. 16:28 Omlor et al. 18:51 Orhan et al. Transcript Be sure to let your colleagues know about the podcast, and please rate and review it on Apple Podcasts, Google Podcasts, Spotify, or wherever you listen to it. Subscribe to the podcast here. Listen to other podcasts produced by the American Psychiatric Association. Browse articles online. How authors may submit their work. Follow the journals of APA Publishing on Twitter. E-mail us at ajp@psych.org
Join us this week as we unpick Polypharmacy and Anticholinergic Burden with Dr Anirudh Kumar, including how to monitor for side effects and make considered deprescribing decisions.
Anticholinergic Cognitive Burden scale: https://corumpharmacy.com/wp-content/uploads/2020/08/Anticholinergic-cognitive-burden-scale.pdf 2023 AGS Beers Criteria: https://agsjournals.onlinelibrary.wiley.com/doi/epdf/10.1111/jgs.18372 Dr. Noll Campbell: linkedin.com/in/noll-campbell-a927ba243 Regenstrief Institute: https://www.regenstrief.org/person/noll-l-campbell/ Dr. Tamara Ruggles: linkedin.com/in/tamara-ruggles-491882251
Contributor: Taylor Lynch MD Educational Pearls: Anticholinergics are found in many medications, including over-the-counter remedies Medications include: Diphenhydramine Tricyclic antidepressants like amitriptyline Atropine Antipsychotics like olanzapine Antispasmodics - dicyclomine Jimsonweed Muscaria mushrooms Mechanism of action involves competitive antagonism of the muscarinic receptor Symptomatic presentation is easily remembered via the mnemonic: Dry as a bone - anhidrosis due to cholinergic antagonism at sweat glands Red as a beet - cutaneous vasodilation leads to skin flushing Hot as a hare - anhidrotic hyperthermia Blind as a bat - pupillary dilation and ineffective accommodation Mad as a hatter - anxiety, agitation, dysarthria, hallucinations, and others Clinical management ABCs Benzodiazepines for supportive care, agitation, and seizures Sodium bicarbonate for TCA toxicity due to widened QRS Activated charcoal if patient present < 1 hour after ingestion Temperature monitoring Contact poison control with questions Physostigmine controversy Acetylcholinesterase inhibitor Black box warning for asystole and seizure Contraindicated in TCA overdoses Crosses blood-brain barrier, so useful for TCA overdoses Indicated only in certain anticholinergic overdose with delirium Disposition Admission criteria include: symptoms >6 hours, CNS findings, QRS prolongation, hyperthermia, and rhabdomyolysis ICU admission criteria include: delirium, dysrhythmias, seizures, coma, or requirement for physostigmine drip References 1. Arens AM, Shah K, Al-Abri S, Olson KR, Kearney T. Safety and effectiveness of physostigmine: a 10-year retrospective review. Clin Toxicol (Phila). 2018;56(2):101-107. doi:10.1080/15563650.2017.1342828 2. Nguyen TT, Armengol C, Wilhoite G, Cumpston KL, Wills BK. Adverse events from physostigmine: An observational study. Am J Emerg Med. 2018;36(1):141-142. doi:10.1016/j.ajem.2017.07.006 3. Scharman E, Erdman A, Wax P, et al. Diphenhydramine and dimenhydrinate poisoning: An evidence-based consensus guideline for out-of-hospital management. Clin Toxicol. 2006;44(3):205-223. doi:10.1080/15563650600585920 4. Shervette RE 3rd, Schydlower M, Lampe RM, Fearnow RG. Jimson "loco" weed abuse in adolescents. Pediatrics. 1979;63(4):520-523. 5. Woolf AD, Erdman AR, Nelson LS, et al. Tricyclic antidepressant poisoning: An evidence-based consensus guideline for out-of-hospital management. Clin Toxicol. 2007;45(3):203-233. doi:10.1080/15563650701226192 Summarized by Jorge Chalit, OMSIII | Edited by Jorge Chalit
Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners. This episode covers Antipsychotic Side Effects with our very own expert Dr Alex Raben, a staff psychiatrist in chronic care at the Centre for Addiction and Mental Health in Toronto. Dr. Raben graduated from medical school and completed residency at the University of Toronto. His academic interests include teaching and medical education scholarship with a particular interest in novel modalities of knowledge translation within the field of psychiatry. He is a founding member and Executive Director of PsychEd, this educational psychiatry podcast which aims to empower medical learners to seek out current knowledge from mental health experts to share with their colleagues around the world. The learning objectives for this episode are as follows: By the end of this episode, the listener will be able to… Outline the side effects of antipsychotics and their known/potential mechanisms Discuss management options for the different side effects Identify which antipsychotics are more likely to cause certain side effects Guest: Dr Alex Raben Hosts: Angad Singh and Kate Braithwaite Audio editing by: Angad Singh Show notes by: Angad Singh and Kate Braithwaite Interview Content: Introduction - 0:00 Primer on antipsychotics - 1:54 Anti-dopamine side effects - 5:04 Drug potency as it relates to side effects - 38:46 Anticholinergic side effects - 41:37 Antiadrenergic side effects - 47:30 Metabolic side effects - 50:29 Sedation - 56:46 Please note that this episode does not include a discussion of the life threatening side effects of antipsychotics. These include neuroleptic malignant syndrome, torsades de pointes, laryngospasm, and seizure. Resources: PsychEd Episode 10: Treatment of Schizophrenia Part II with Dr. Albert Wong — PsychEd Podcast PsychEd Episode 60: Metabolic Psychiatry with Dr. Cindy Calkin – Psyched Podcast AIMSExtendedSample - YouTube Anticholinergic Mnemonics: Toxicology Mnemonic Challenge • LITFL • Toxicology Conundrum References: de Silva VA, Suraweera C, Ratnatunga SS, Dayabandara M, Wanniarachchi N, Hanwella R. Metformin in prevention and treatment of antipsychotic induced weight gain: a systematic review and meta-analysis. BMC psychiatry. 2016;16:1-0. Migirov A, Datta AR. Physiology, Anticholinergic Reaction. [Updated 2023 Jul 31]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. Available from: https://www.ncbi.nlm.nih.gov/books/NBK546589/ Miller DD. Atypical antipsychotics: sleep, sedation, and efficacy. Prim Care Companion J Clin Psychiatry. 2004;6(Suppl 2):3-7. PMID: 16001094; PMCID: PMC487011. Roerig JL, Steffen KJ, Mitchell JE. Atypical antipsychotic-induced weight gain: insights into mechanisms of action. CNS drugs. 2011;25:1035-59. Stahl SM. Stahl's essential psychopharmacology: neuroscientific basis and practical applications. Cambridge university press; 2021. Stroup TS, Gray N. Management of common adverse effects of antipsychotic medications. World Psychiatry. 2018;17(3):341-56. For more PsychEd, follow us on Instagram (@psyched.podcast), Twitter (@psychedpodcast), and Facebook (PsychEd Podcast). You can provide feedback by email at psychedpodcast@gmail.com. For more information, visit our website at psychedpodcast.org.
It's one of history's favorite poisons, Deadly Nightshade! It's also one of my favorite plants, because it is both pretty and horribly toxic. The flowers are my favorite color! Music by James Milor from Pixabay Information provided by: Atropa Belladonna intoxication: a case report by Mohamed Adnane Berdai, et al. (2012) https://www.europeana.eu/en/exhibitions/magical-mystical-and-medicinal/belladonna https://sites.evergreen.edu/plantchemeco/deadly-nightshade/ https://www.rcpe.ac.uk/heritage/deadly-nightshade-botanical-biography https://www.rxlist.com/how_do_anticholinergic_agents_work/drug-class.htm An Evidence-Based Systematic Review of Belladonna by the Natural Standard Research Collaboration by Catherine Ulbricht, et al. (2004) https://www.fs.usda.gov/wildflowers/ethnobotany/Mind_and_Spirit/belladonna.shtml https://en.wikipedia.org/wiki/Anticholinergic https://en.m.wikipedia.org/wiki/Atropa_belladonna https://www.woodlandtrust.org.uk/trees-woods-and-wildlife/plants/wild-flowers/deadly-nightshade/
Did you know that overactive bladder (OAB) affects approximately 35 million people in the United States and negatively impacts psychosocial functioning and quality of life? Credit available for this activity expires: 9/25/24 Earn Credit / Learning Objectives & Disclosures: https://www.medscape.org/viewarticle/996748?ecd=bdc_podcast_libsyn_mscpedu
In this podcast, James Cave (Editor-in-Chief) and David Phizackerley (Deputy Editor) talk about the September 2023 issue of DTB. They discuss concerns over redacted data in NICE appraisal documents (https://dtb.bmj.com/content/61/9/130). They review a placebo-controlled study that assessed the use of spironolactone for women with acne (https://dtb.bmj.com/content/61/9/132). The main article explores anticholinergic burden and the risk of cognitive decline, dementia and increased mortality associated with long-term use of drugs with anticholinergic activity (https://dtb.bmj.com/content/61/9/135). Please subscribe to the DTB podcast to get episodes automatically downloaded to your mobile device and computer. Also, please consider leaving us a review or a comment on the DTB Podcast iTunes podcast page (https://podcasts.apple.com/gb/podcast/dtb-podcast/id307773309). If you want to contact us please email dtb@bmj.com. Thank you for listening.
Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Diphenhydramine Trade Name Benadryl Indication Allergy, anaphylaxis, sedation, motion sickness, antitussive Action Antagonizes effects of histamine, CNS depression Therapeutic Class Allergy, cold and cough remedy, antihistamine, antitussive Pharmacologic Class Antihistamine Nursing Considerations • May cause drowsiness, anorexia, dry mouth, nausea, chest tightness, thick secretions, hypotension, blurred vision, headache • Anticholinergic effects (dry mouth, blurred vision, constipation, sedation) • Assess purpose of medication prior to giving it • Assess allergies, sleep patterns, cough and lung sounds • Patient should avoid other over-the-counter cough and cold remedies
Have you been more forgetful lately? Confused? Hallucinating?? Have you had dry mouth associated with your PD medications? It's not just YOU! This week we are discussing Anticholinergic medications. You can find more details here Please be sure to check out the Aware in Care Kit from Parkinson's Foundation. It could be a true gamechanger in the event of a hospitalization, even an elective one. We discussed in this episode of the PWP: Episode 5: Hospital Stays and PWP - Aware in Care Please support this podcast and our endeavors by becoming a co-producer of the show! Sign up as a Patreon supporter here at https://www.patreon.com/pdwarriors Also, you can leave a one time tip in our virtual tip jar at: https://paypal.me/hylandptw Don't forget about our YouTube channel!!
Visit: https://nursing.com/140meds to request your free copy of "140 Must Know Meds" Generic Name Benztropine Trade Name Cogentin Indication Treatment for Parkinson's disease Action Exhibits anticholinergic properties (blocks acetylcholine) in the CNS to reduce rigidity and tremors Therapeutic Class Antiparkinson agent Pharmacologic Class Anticholinergic Nursing Considerations • May lead to arrhythmias, hypotension, palpitations, and tachycardia • Anticholinergic effects like constipation, dry mouth • Assess for extrapyramidal symptoms • Instruct patient to take as directed • Instruct patient to maintain good oral hygiene
Watch the full video interview on YouTube here: https://bit.ly/498drrogerseheult Dr. Roger Seheult (IG: @medcram) is currently an Associate Clinical Professor at the University of California, Riverside School of Medicine and an Assistant Clinical Professor at the School of Medicine and Allied Health at Loma Linda University. He's quadruple board-certified in Internal Medicine, Pulmonary Diseases, Critical Care Medicine and Sleep Medicine through the American Board of Internal Medicine. Dr. Seheult is the co-founder of MedCram, a medical online education company founded in 2012. He has over 1.4 million subscribers and educates his viewers on medical topics. In this episode, we discuss: Why sleep is so critical What is the ideal time to go to sleep? The benefits of N3 sleep Sleep recommendations for night shift workers New research about melatonin The best way to optimize your circadian rhythm Dr. Seheult's typical day of managing his light exposure Why you should pack your calories into the morning 90% of people have a delayed circadian rhythm Natural strategies for people who can't sleep What is sleep restriction therapy? Symptoms of sleep apnea in men vs. women Dr. Seheult's thoughts on mouth taping Tips to start sleeping better tonight Anticholinergic medications are linked to Alzheimer's disease Why Dr. Seheult switched to a plant-based diet Dr. Seheult's typical day of eating + how he breaks his fast How certain animal products cause inflammation in the body Get your vitamin D levels checked Show sponsors: Seed
https://psychiatry.dev/wp-content/uploads/speaker/post-10004.mp3?cb=1664238676.mp3 Playback speed: 0.8x 1x 1.3x 1.6x 2x Download: Relapse of first-episode schizophrenia patients and neurocognitive impairment: The role of dopaminergic and anticholinergic burden – PubMed Manuel J Cuesta et al.Full EntryRelapse of first-episode schizophrenia patients and neurocognitive impairment: The role of dopaminergic and anticholinergic burden – PubMed
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In this episode, I will be doing a RAPID FIRE Question-Answer Round of around 15-17 questions about ANTICHOLINERGIC DRUGS, a sort of Quick Revision or Summary we can say. I am sure this will be a great closing session of this topic and will help you all to listen the overall topic altogether at a time period of around 15 minutes. It was great fun and exercise doing this episode, I am sure you all gonna like it too.. For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also. You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!! You can access various links via- https://linktr.ee/ispharmacologydifficult
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.In this episode, I will be doing a RAPID FIRE Question-Answer Round of around 15-17 questions about ANTICHOLINERGIC DRUGS, a sort of Quick Revision or Summary we can say.I am sure this will be a great closing session of this topic and will help you all to listen the overall topic altogether at a time period of around 15 minutes.It was great fun and exercise doing this episode, I am sure you all gonna like it too..For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also.You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!You can access various links via- https://linktr.ee/ispharmacologydifficult
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. A quick, celebrated poetic August weather update will break the ice today!! In this episode, I will be discussing Atropine poisoning, its diagnosis and cure. But before that I will quickly cover points related to Anticholinergic drug effects on Respiratory tract states and also on the Gut. Hence effect of variety of Atropine congeners like Dicyclomine, propantheline, Ipratropium bromide, Tiotropium bromide, Glycopyrrolate, Pirenzepine and Telenzepine will be known in states of COPD, Acute bronchial Asthma, Preanaesthetic medication, Peptic ulcer, colicky spasms, etc. And the sealing of the topic will be by an account of Belladonna/Datura/Atropine poisoning. For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also. You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!! You can access various links via- https://linktr.ee/ispharmacologydifficult
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.A quick, celebrated poetic August weather update will break the ice today!!In this episode, I will be discussing Atropine poisoning, its diagnosis and cure. But before that I will quickly cover points related to Anticholinergic drug effects on Respiratory tract states and also on the Gut.Hence effect of variety of Atropine congeners like Dicyclomine, propantheline, Ipratropium bromide, Tiotropium bromide, Glycopyrrolate, Pirenzepine and Telenzepine will be known in states of COPD, Acute bronchial Asthma, Preanaesthetic medication, Peptic ulcer, colicky spasms, etc.And the sealing of the topic will be by an account of Belladonna/Datura/Atropine poisoning.For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also. You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!You can access various links via- https://linktr.ee/ispharmacologydifficult
Nursing Mnemonics Show by NRSNG (Memory Tricks for Nursing School)
A cholinergic crisis can occur if the body stops properly breaking down Acetylcholine. This can cause overactivity of Acetylcholine at the neuromuscular junction. Acetylcholine is part of Rest & Digest (Parasympathetic) – so we see overactive digestion and secretion.
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In today's episode, I will be discussing effects and applications of Anticholinergic drugs- Atropine and congener drugs on Sweating and also on Genitourinary system. To begin with, effects on sweating will be discussed, details like mechanism, Atropine fever , etc will be covered. In next step, Anticholinergic drug effects on Genitourinary system will be discussed. Under this head all details will be covered and many congener drugs will be listed and discussed. Drugs like Dicyclomine, Oxybutynin, Valethamate, Drotaverine, Tolterodine, Papaverine, Fesoterodine, Flavoxate, etc will be thrown light upon. This inflow of knowledge and information will be halted to resume and revive back in short duration, Chao till next conversation... Vous Parle Bientot! (Talk to you soon!) For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also. You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!! You can access various links via- https://linktr.ee/ispharmacologydifficult
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.In today's episode, I will be discussing effects and applications of Anticholinergic drugs- Atropine and congener drugs on Sweating and also on Genitourinary system.To begin with, effects on sweating will be discussed, details like mechanism, Atropine fever , etc will be covered.In next step, Anticholinergic drug effects on Genitourinary system will be discussed. Under this head all details will be covered and many congener drugs will be listed and discussed.Drugs like Dicyclomine, Oxybutynin, Valethamate, Drotaverine, Tolterodine, Papaverine, Fesoterodine, Flavoxate, etc will be thrown light upon.This inflow of knowledge and information will be halted to resume and revive back in short duration, Chao till next conversation... Vous Parle Bientot! (Talk to you soon!)For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also. You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!You can access various links via- https://linktr.ee/ispharmacologydifficult
Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/DiphenhydramineBenadrylNursingConsiderations Generic Name Diphenhydramine Trade Name Benadryl Indication Allergy, anaphylaxis, sedation, motion sickness, antitussive Action Antagonizes effects of histamine, CNS depression Therapeutic Class Allergy, cold and cough remedy, antihistamine, antitussive Pharmacologic Class Antihistamine Nursing Considerations • May cause drowsiness, anorexia, dry mouth, nausea, chest tightness, thick secretions, hypotension, blurred vision, headache • Anticholinergic effects (dry mouth, blurred vision, constipation, sedation) • Assess purpose of medication prior to giving it • Assess allergies, sleep patterns, cough and lung sounds • Patient should avoid other over-the-counter cough and cold remedies
Want to experience the greatest in board studying? Check out our interactive question bank podcast- the FIRST of its kind here: emrapidbombs.supercast.com. Iltifat Husain and Blake Briggs team up in the wilderness to deliver content on anticholinergic poisoning LIVE from Linville Gorge, a National Forest wilderness area in North Carolina. Name a single EM podcast that records LIVE from a campfire. Go ahead, we're waiting…
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.In this episode , I will be heralding a new topic namely Anticholinergic/Antimuscarinic drugs. This is introductory episode for these agents. Atropine is hallmark/prototype drug and then I will be giving a long lively list of other drugs too!The main heads are Natural Alkaloids, Semisynthetic derivatives or drugs and Synthetic derivatives and then they have their subheads too!With a quick remark on general Pharmacokinetics of these agents, I will wrap this episode actually in some minutes, hope you got to spare and invest, it's worth it!For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also. You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!You can access various links via- https://linktr.ee/ispharmacologydifficult
Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. In this episode , I will be heralding a new topic namely Anticholinergic/Antimuscarinic drugs. This is introductory episode for these agents. Atropine is hallmark/prototype drug and then I will be giving a long lively list of other drugs too! The main heads are Natural Alkaloids, Semisynthetic derivatives or drugs and Synthetic derivatives and then they have their subheads too! With a quick remark on general Pharmacokinetics of these agents, I will wrap this episode actually in some minutes, hope you got to spare and invest, it's worth it! For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also. You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!! You can access various links via- https://linktr.ee/ispharmacologydifficult
Download the cheat: https://bit.ly/50-meds View the lesson: https://bit.ly/BenztropineCogentinNursingConsiderations Generic Name Benztropine Trade Name Cogentin Indication Treatment for Parkinson's disease Action Exhibits anticholinergic properties (blocks acetylcholine) in the CNS to reduce rigidity and tremors Therapeutic Class Antiparkinson agent Pharmacologic Class Anticholinergic Nursing Considerations • May lead to arrhythmias, hypotension, palpitations, and tachycardia • Anticholinergic effects like constipation, dry mouth • Assess for extrapyramidal symptoms • Instruct patient to take as directed • Instruct patient to maintain good oral hygiene
Do anticholinergic medications increase the risk of long-term cognitive decline and dementia? In this podcast, we will review the latest research examining the relationship between anticholinergic medication use and cognitive decline.CME: Take the Podcast CME Post-Test here. Not subscribed to earn CME credit for listening? Click here to start earning CME credit for podcast episodes!Published On: 05/02/2022Duration: 15 minutes, 58 secondsReferenced Article: “Anticholinergic Drugs and Risk of Cognitive Impairment and Dementia,” The Carlat Hospital Psychiatry Report, October/November/December 2021Victoria Hendrick, MD, Zachary N. Davis, BS, and Shelly Gray, PharmD, have disclosed no relevant financial or other interests in any commercial companies pertaining to this educational activity.
Thank you Christian 'Batman' Deveraux, OMS IV and Dave 'Robin" Brown OMS III for developing this very high yield podcast! The high yield content lasts for quite a while and would not be a quick listen for only that content. It is more extended than usual because of the attention to shelf content about anticholinergic medications, treatment of movement disorders associated with use of antipsychotic medications and beyond. This is followed by a discussion reviewing the correlation between development of dementia and use of anticholinergic medications. We enjoyed our discussion and hope you find it as interesting as we did! Thank you Jordan Turner for creating the perfect bumper music!
Our first episode dedicated to a class of medications. This episode we explore the autonomic nervous system and medications that can affect it called Adrenergic and Cholinergic Medications.
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In this episode, NPS MedicineWise medical advisor Dr Caroline West talks to our other medical adviser Dr Kate Annear about the cumulative effects of anticholinergic medicines. Not always front of mind, these medicines can cause many problematic side effects and can lead to poor health outcomes including increased risk of falls and cognitive decline. We cover what these medicines are and what can be done. Reviewing people's multiple medicines and considering deprescribing or finding alternative treatments can reduce ‘anticholinergic burden'.
This episode will hopefully convince you to never suddenly discontinue clozapine (and to do a thorough home medication review) Click HERE to leave a review of the podcast!Subscribe HERE!References:All references for Episode 58 are found on my Read by QxMD collectionSupport the show (https://www.buymeacoffee.com/errxpodcast)
This week, Peter Simons covers an article finding that anticholinergic drugs are linked to cognitive impairment, an article by Allen Frances about overprescription of antidepressants, and an article warning about reductionistic assumptions about biomarkers in psychiatry. Anticholinergic Medications Linked to Cognitive Impairment in Schizophrenia Allen Frances Takes on the Over-Prescription of Antidepressants We Need Clear Thinking About Biomarkers in Psychiatry to Avoid Bioreductionism Visit madinamerica.com for more news, articles and research updates.
Interview with Shannon Rice on her article, "Anticholinergic Cognitive Burden in Older People Over Acute Admission," featured in The Senior Care Pharmacist journal.
Trying to keep up with the general medicine literature but, in an environmentally friendly frenzy, you've used up all your shiny BMJs as wrapping paper?Your ears are in the right place.In this episode, Jon and Barney are joined by Alvin and Camille, and together we wade through the murky medical literature so you don't have to.1) Blockbuster trial of the month: Semaglutide - the saviour of NASH? (04:40)2) Bereavement and stroke - what is the link? (08:05)3) Combo pill may, or may not, save us all (10:40)4) Topic of the month: Statins in the elderly. Maybe the elderly benefit more than we think, and those side effects aren't as significant as your patient thinks... (13:10)5) Which crystalloid in DKA? There can only be one winner. (19:00)6) What's the link between sarcopenia and orthostatic hypotension? (21:18)7) Natural remedies which might actually work in UC (24:05)8) Inotropic drugs which could save lives in HFrEF (27:22)9) Why you should check Vit D in your asthmatics (30:25)10) Anticholinergic drugs and dementia risk (33:15)11) A Case Study of ST elevation in a young patient (36:16)
There are medications that worsen cognitive function and all mental health providers should be aware, and work on optimizing sensorium. In this episode, we'll cover a spectrum of sensorium disruptions and medications that you need to look out for. Link to Blog. Link to Resource Library.
Organoids are miniature artificial organs built from stem cells that may help drug testing; DNA origami - Playing with DNA to make micron level structures with interesting properties; Research on the anti-inflammatory Low Dose naltrexone for many conditions, including MS, Alzheimer's and early Coronavirus infection; How wearing a face mask could actually increase immunity to Coronavirus! Balancing calcium intake to prevent osteoporosis but not induce kidney stones; Rapamycin is an interesting anti-aging drug by reducing muscle loss and other health benefits; Anticholinergic drugs such as antihistamines cause cognitive impairment; A drug for cat Coronavirus is promising to treat current human Coronavirus, SARS-CoV-2
Organoids are miniature artificial organs built from stem cells that may help drug testing; DNA origami - Playing with DNA to make micron level structures with interesting properties; Research on the anti-inflammatory Low Dose naltrexone for many conditions, including MS, Alzheimer's and early Coronavirus infection; How wearing a face mask could actually increase immunity to Coronavirus! Balancing calcium intake to prevent osteoporosis but not induce kidney stones; Rapamycin is an interesting anti-aging drug by reducing muscle loss and other health benefits; Anticholinergic drugs such as antihistamines cause cognitive impairment; A drug for cat Coronavirus is promising to treat current human Coronavirus, SARS-CoV-2
A common class of drugs called anticholinergics seems linked to an increased risk of Alzheimer’s Disease in a new study led by University of California, San Diego
Many patients over age 65 take daily medications that have anticholinergic properties. We know the addition of these drugs can affect quality of life and cognition. In this episode, we talk with Dr. Kristin Meyer, an expert in geriatrics to explore the latest data and discuss what Pharmacists can do to promote the appropriate use of anticholinergics.Additional Resources/ReferencesBeers Criteria:By the 2019 American Geriatrics Society Beers Criteria® Update Expert Panel. American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults. J Am Geriatr Soc. 2019;67(4):674-694. doi:10.1111/jgs.15767Anticholinergic Risk Scale:Rudolph JL, Salow MJ, Angelini MC, McGlinchey RE. The Anticholinergic Risk Scale and Anticholinergic Adverse Effects in Older Persons. Arch Intern Med. 2008;168(5):508–513. doi:10.1001/archinternmed.2007.106Recent arge study associating anticholinergics with dementia:Coupland CAC, Hill T, Dening T, Morriss R, Moore M, Hippisley-Cox J. Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study. JAMA Intern Med. 2019;179(8):1084–1093. doi:10.1001/jamainternmed.2019.0677This episode is accredited for CPE. For CE details and to claim credit click here: https://bit.ly/2UT97Ww See omnystudio.com/listener for privacy information.
Many patients over age 65 take daily medications that have anticholinergic properties. We know the addition of these drugs can affect quality of life and cognition. In this episode, we talk with Dr. Kristin Meyer, an expert in geriatrics to explore the latest data and discuss what Pharmacists can do to promote the appropriate use of anticholinergics. Additional Resources/References Beers Criteria: By the 2019 American Geriatrics Society Beers Criteria® Update Expert Panel. American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults. J Am Geriatr Soc. 2019;67(4):674-694. doi:10.1111/jgs.15767 Anticholinergic Risk Scale: Rudolph JL, Salow MJ, Angelini MC, McGlinchey RE. The Anticholinergic Risk Scale and Anticholinergic Adverse Effects in Older Persons. Arch Intern Med. 2008;168(5):508–513. doi:10.1001/archinternmed.2007.106 Recent arge study associating anticholinergics with dementia: Coupland CAC, Hill T, Dening T, Morriss R, Moore M, Hippisley-Cox J. Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study. JAMA Intern Med. 2019;179(8):1084–1093. doi:10.1001/jamainternmed.2019.0677 This episode is accredited for CPE. For CE details and to claim credit click here: https://bit.ly/2UT97Ww See omnystudio.com/listener for privacy information.
Many patients over age 65 take daily medications that have anticholinergic properties. We know the addition of these drugs can affect quality of life and cognition. In this episode, we talk with Dr. Kristin Meyer, an expert in geriatrics to explore the latest data and discuss what Pharmacists can do to promote the appropriate use of anticholinergics. Additional Resources/References Beers Criteria: By the 2019 American Geriatrics Society Beers Criteria® Update Expert Panel. American Geriatrics Society 2019 Updated AGS Beers Criteria® for Potentially Inappropriate Medication Use in Older Adults. J Am Geriatr Soc. 2019;67(4):674-694. doi:10.1111/jgs.15767 Anticholinergic Risk Scale: Rudolph JL, Salow MJ, Angelini MC, McGlinchey RE. The Anticholinergic Risk Scale and Anticholinergic Adverse Effects in Older Persons. Arch Intern Med. 2008;168(5):508–513. doi:10.1001/archinternmed.2007.106 Recent arge study associating anticholinergics with dementia: Coupland CAC, Hill T, Dening T, Morriss R, Moore M, Hippisley-Cox J. Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study. JAMA Intern Med. 2019;179(8):1084–1093. doi:10.1001/jamainternmed.2019.0677 This episode is accredited for CPE. For CE details and to claim credit click here: https://bit.ly/2UT97Ww
Real Life Pharmacology - Pharmacology Education for Health Care Professionals
Rivastigmine is an acetylcholinesterase inhibitor used in the management of certain dementias. I discuss rivastigmine pharmacology on this episode. Weight loss is a potential adverse effect of rivastigmine. It is important to monitor weights. Anticholinergic medications such as diphenhydramine can blunt the effects of rivastigmine. Rarely, acetylcholinesterase inhibitors like rivastigmine can cause bradycardia.
Ready for some fright-night fun Rangers? PoisonBoy is joined by the Copperhead Kid himself, Jarratt Lark and our newest Ranger, the Blonde Widow, Dr. Morgan Smith to discuss all sorts of terrifying topics. Join us to learn why witches ride broomsticks and why brown recluse and black widow spiders are so misunderstood. It's all the Halloween horror without the sore teeth from eating all that chocolate, plus you might actually learn something. Or maybe not. Either way - you are guaranteed to have a good time, so what are you waiting for?
Get our free clinical lab guide: https://www.medgeeks.co/labguide - Today, we're going to discuss anticholinergic toxicity. This is an important one as there are a ton of medications out there that have anticholinergic properties. We have a 75 year old female with a past medical history of Parkinsons, COPD, hypertension, and hyperlipidemia. She presents from a skilled nursing facility with altered mental status. Per the SNF, the patients baseline is alert and oriented x4 but does need assistance with ADLs. This morning the patient had intermittent agitation and was disoriented to self, place, and time. Patient had a temp of 102.3, HR 120, BP 130/89, RR 16, and 98% O@ RA. Of note, the patient has not urinated in over 12 hours. Per staff, she was seen yesterday for a low back musculoskeletal strain and was given flexeril and ibuprofen. Let's finish walking through this case together and discuss anticholinergic toxicity. - Follow us on Instagram here: https://www.instagram.com/medgeeksinc - Check out our course material here: https://learn.medgeeks.co - This podcast should not be used in any legal capacity whatsoever, including but not limited to establishing standard of care in a legal sense or as a basis for expert witness testimony. No guarantee is given regarding the accuracy of any statements or opinions made on the podcast, video, or blog.
MDI. DPI. Anticholinergic. Beta-agonist. Say what??? There are so many different meds for COPD, how do you know if you're on the right one? How do you know you're using it correctly? Find out more in this episode. Subscribe to us on YouTube and join us every other week on Facebook to get the latest updates and your questions answered LIVE! --- Send in a voice message: https://anchor.fm/copdnavigator/message Support this podcast: https://anchor.fm/copdnavigator/support
Join the EMGuideWire team as they enter the TOXIDome once again and review Toxidromes with Dr. Kopec!
Join the Dr. Kathryn Kopec as she joins the EMGuideWire team to discuss how the Toxicologist approaches the patient who has a potential exposure to an intoxicant. Review your basic evaluation and treatment options and learn how to recognize those all important toxidromes!
Dr. K explains what older adults and families should know about anticholinergic medications and their negative impact on brain health. Many commonly used over-the-counter and prescription medications are anticholinergic, and on the Beer's List of Medications Older Adults Should Avoid or Use With Caution. Learn about seven often-used types of medication that are anticholinergic, who should particularly be careful about these medications, what to do if you're taking them, and more. The post 073 Anticholinergic Medications & Protecting Brain Health appeared first on Better Health While Aging.
Physostigmine for Anticholinergic toxicity
Knock the wind out of asthma with tips from Dr Denitza Blagev, a pulmonologist and intensivist who currently serves as Director for the Schmidt Chest Clinic at Intermountain Medical Center in Murray, Utah. We simplify the approach to diagnosis, spirometry, patient counseling, choice of agent, stepwise therapy, and de-escalation...plus, a little myth busting. Special thanks to Dr Cyrus Askin for writing and producing this episode and to Dr Bryan Brown for his wonderful infographics. Full show notes available at http://thecurbsiders.com/podcast Join our mailing list and receive a PDF copy of our show notes every Monday. Rate us on iTunes, recommend a guest or topic and give feedback at thecurbsiders@gmail.com. Time Stamps 00:00 Disclaimer 00:32 Intro 01:44 Picks of the week 04:38 Guest bio 06:20 Getting to know our guest 11:50 Clinical case and approach to the patient with dyspnea 16:38 How to explain asthma to a patient 17:22 Are PFTs needed for diagnosis and management of asthma? 18:44 Methacholine challenge and who needs one 21:15 Is imaging needed? 22:09 Typical PFT patterns in asthma 24:23 Utility and use of peak expiratory flows 25:45 Cough variant asthma 26:34 Physical exam in patient with asthma 27:45 Lab workup 29:07 Initial treatment and inhaler teaching 33:10 Stepwise therapy for asthma 37:27 De-escalation of therapy 39:18 Levalbuterol versus albuterol 40:20 Asthma action plans 43:06 Who needs a sputum sample 45:25 How to treat asthma exacerbations 48:05 Asthma therapy for hospitalized patients 51:10 Azithromycin and asthma 53:40 Who needs a referral 55:24 Are beta blockers safe in asthma? 56:08 Anticholinergic therapy and asthma 57:26 Take home points 58:58 Paul tells a story about asthma 59:55 Outro Tags: asthma, inhaler, teaching, eosinophilia, albuterol, cough, variant, methacholine, spirometry, xray, pft, peak, flow, fev1, sputum, step, laba, lama, beta, agonist, azithromycin, symptoms, steroids, assistant, care, education, doctor, family, foam, foamed, health, hospitalist, hospital, internal, internist, nurse, meded, medical, medicine, practitioner, professional, primary, physician, resident, student
Podcast summary of articles from the October 2017 edition of Journal of Emergency Medicine from the American Academy of Emergency Medicine. Topics include trauma patients on anticoagulation, terrorist stabbings, anticholinergic syndrome, risperidone use in intoxicated patients, chest pain admissions, and board review on cellulitis. Guest speakers include Dr. Michael Weinstock from the Ohio State University and Dr. Tona Rios-Alba from the Cleveland Clinic Emergency Services Institute.
We review this blog post by Bryan Hayes, an ED pharmacist (@PharmERToxGuy), on the use of physostigmine in anticholinergic toxicity. We then review anticholinergic toxidrome using Rosen's, Tintinalli's, and Goldfrank's as a guide. Thanks for listening! Lauren Westafer and Jeremy Faust
Pete and Nick are joined by geriatric registrars Emma and Chris. In this COTEcast we are tackling the issues around polypharmacy in the elderly. We discuss why it is a problem and how to manage it. We also offer some tips for junior doctors who are starting new jobs soon on how to approach a patient with polypharmacy. Links: STOPP/START tool: https://www.networks.nhs.uk/nhs-networks/nhs-cumbria-ccg/medicines-management/guidelines-and-other-publications/Stop%20start%20pdf%20final%20Feb%202013%20version.pdf Deprescribing Canadian initiative: http://deprescribing.org/resources/deprescribing-guidelines-algorithms/ Anticholinergic burden score calculator: http://www.agingbraincare.org/uploads/products/ACB_scale_-_legal_size.pdf
Dominate the diagnosis and management of dementia with tips from international expert Dr. Stephen Dekosky, Professor of Neurology, and deputy director of the McKnight Brain Institute at the University of Florida. Filled with clinical pearls, we cover everything from basic testing to advanced imaging modalities, as well as current and future therapies for dementia. This episode is a must listen. Big thanks to the American Academy of Neurology for setting up this interview. Full show notes are available at http://thecurbsiders.com/podcast Join our newsletter mailing list. Rate us on iTunes, recommend a guest or topic and give feedback at thecurbsiders@gmail.com. Time Stamps 00:00 Intro 02:20 Rapid fire questions 04:40 Defining dementia 08:40 Choosing a clinical test for dementia 17:20 Diagnostic labs 19:00 Genetic and CSF testing 25:46 Advanced brain imaging 28:18 Preclinical Alzheimer’s disease (AD) 32:17 Routine CNS imaging 36:18 Initiating medical therapy 39:35 Differentiating MCI and dementia 41:45 Vascular Dementia 44:10 CSF testing for AD 45:15 Vitamins, supplements, and foods as treatment or prevention 50:56 Mental exercise for AD prevention 52:36 Anticholinergic, benzos and dementia 54:46 Future directions 57:55 Outro Tags: Alzheimers, assistant, care, education, dementia, disease, doctor, family, foam, foamed, health, hospitalist, hospital, internal, internist, neurology, nurse, medicine, medical, mri, pet, primary, physician, resident, student, vascular
The vast world of toxicology will be primarily boiled into Anticholinergic syndrome for this discussion. When or where will our patients be exposed to substantial amounts of anticholinergics? Those of us that are allergically challenged have enough antihistamines in the house to make us look like our cuddly Easter friends on the track image. Dig into this podcast to discover what other drugs and chemicals we use without a second thought and what combination of symptoms we should be hunting for to diagnose this overdose. Catch the show notes at: http://cbcemp.proboards.com/thread/44/toxicology
We are back with a quick dose of high quality, high yield emergency medicine board review. Episode 4 touches on Ascending cholangitis, NEXUS, SSS, Subarachnoid hemorrhage, Anticholinergic syndrome, Lead poisoning...and many mnemonics. The post Podcast Ep 4: Mnemonics, SSS, Subarachnoid Hemorrhage, & More appeared first on RoshReview.com.
Show notes at www.medicalcasespodcast.libsyn.com. Remember in medical school when you were taught to treat the patient and not the numbers? It sounded so good, right? So why are we so aggressive with treating fever in patients with sepsis? This episode reviews the article "Acetaminophen for Fever in Critically Ill Patients with Suspected Infection". Bottom line: for septic patients with fever, you can use acetaminophen to treat symptoms but there is no mortality benefit. Furthermore, if patients are persistently tachycardic despite adequate resuscitation and all other causes of tachycardia have been ruled out there is no harm in giving acetaminophen to control fever/ tachycardia. Background: acetaminophen is often used to control fever in patients with suspected infection in the ICU - there is little data to suggest that this is beneficial. Population: 700 ICU patients with fever (temp ≥38°C) and suspected source of infection Design: Multi-center, prospective, parallel-group, blinded, randomized, controlled trial. Intervention: 1 gm IV acetaminophen Q6H until 1) ICU discharge, 2) Resolution of fever, 3) Cessation of antimicrobial therapy OR 4) Death Control: Placebo Q6H Results: Primary Outcome - No difference in ICU free days to day 28. Secondary Outcome - No significant differences between the acetaminophen group and the placebo group with respect to mortality at day 28 or at day 90 It should be noted that acetaminophen WAS associated with a shorter ICU stay among survivors but a LONGER stay among non-survivors. Acetaminophen has a low chance of harming your patient but it is clear that there is no pressing medical indication (other than discomfort) to treat mild fever in sepsis. Keep in mind that we are talking about fever in suspected infection. There are many other cases where temperature management of some sort IS indicated. This is often acheived through medications or external cooling. Examples include: Neuroleptic malignant syndrome Serotonin syndrome Environmental exposure like heat exhaustion and heat stroke Post cardiac arrest - 33℃ vs 36℃ Malignant hyperthermia Anticholinergic toxidrome Brain trauma. Premies with Hypoxic-Ischemic Encephalopathy From the article - Young, Paul, Manoj Saxena, and Rinaldo Bellomo. "Acetaminophen for Fever in Critically Ill Patients with Suspected Infection." New England Journal of Medicine N Engl J Med 373.23 (2015): 2215-224.
Nursing Mnemonics Show by NRSNG (Memory Tricks for Nursing School)
Anticholinergics- side effects Can’t see – burred vision Can’t pee – urinary retention Can’t spit – dry mouth Can’t s*** – constipation Cholinergic Crisis – Signs and symptoms SLUDGE Salivation Lacrimation Urination Defecation Gastric upset Emesis… The post Ep12 Cholinergic, Anticholinergic (SLUDGE) appeared first on NURSING.com.
This week we delve into the anticholinergic toxidrome with a focus on management and the use of physostigmine. https://media.blubrry.com/coreem/content.blubrry.com/coreem/Episode_48_0_Final_Cut.m4a Download Leave a Comment Tags: Anticholinergic, Diphenhydramine, Physostigmine, TCA, Toxicology Show Notes Howland M. Antidotes in Depth (A12): Physostigmine Salicylate. In: Nelson LS, Lewin NA, Howland M, Hoffman RS, Goldfrank LR, Flomenbaum NE. eds. Goldfrank's Toxicologic Emergencies, 9e . New York, NY: McGraw-Hill; 2011. Velez LI, Feng SY: Anticholinergics, in Marx JA, Hockberger RS, Walls RM, et al (eds): Rosen's Emergency Medicine: Concepts and Clinical Practice, ed 8. St. Louis, Mosby, Inc., 2010, (Ch) 150: p 1970-5. Anticholinergic Infographic (B...
This week we delve into the anticholinergic toxidrome with a focus on management and the use of physostigmine. https://media.blubrry.com/coreem/content.blubrry.com/coreem/Episode_48_0_Final_Cut.m4a Download Leave a Comment Tags: Anticholinergic, Diphenhydramine, Physostigmine, TCA, Toxicology Show Notes Howland M. Antidotes in Depth (A12): Physostigmine Salicylate. In: Nelson LS, Lewin NA, Howland M, Hoffman RS, Goldfrank LR, Flomenbaum NE. eds. Goldfrank's Toxicologic Emergencies, 9e . New York, NY: McGraw-Hill; 2011. Velez LI, Feng SY: Anticholinergics, in Marx JA, Hockberger RS, Walls RM, et al (eds): Rosen's Emergency Medicine: Concepts and Clinical Practice, ed 8. St. Louis, Mosby, Inc., 2010, (Ch) 150: p 1970-5. Anticholinergic Infographic ...
This week we delve into the anticholinergic toxidrome with a focus on management and the use of physostigmine. https://media.blubrry.com/coreem/content.blubrry.com/coreem/Episode_48_0_Final_Cut.m4a Download Leave a Comment Tags: Anticholinergic, Diphenhydramine, Physostigmine, TCA, Toxicology Show Notes Howland M. Antidotes in Depth (A12): Physostigmine Salicylate. In: Nelson LS, Lewin NA, Howland M, Hoffman RS, Goldfrank LR, Flomenbaum NE. eds. Goldfrank’s Toxicologic Emergencies, 9e . New York, NY: McGraw-Hill; 2011. Velez LI, Feng SY: Anticholinergics, in Marx JA, Hockberger RS, Walls RM, et al (eds): Rosen’s Emergency Medicine: Concepts and Clinical Practice, ed 8. St. Louis, Mosby, Inc., 2010, (Ch) 150: p 1970-5. Anticholinergic Infographic (BrianandKloss.com)
Question: A 76-year-old patient has urinary incontinence diagnosed because of instability of the detrusor muscle. Which of the following describes a form of management of this type of incontinence? Select all that apply. Answer: A. Anticholinergic drugs, such as Ditropan B. Bladder training Rationale: Incontinence caused by instability of the detrusor muscle in the bladder […] The post QOD 56: Treatment for Urinary Incontinence (GI/GU/Basic Care and Comfort) appeared first on NURSING.com.
NRSNG NCLEX® Question of the Day (Nursing Podcast for NCLEX® Prep and Nursing School)
Question: A 76-year-old patient has urinary incontinence diagnosed because of instability of the detrusor muscle. Which of the following describes a form of management of this type of incontinence? Select all that apply. Answer: A. Anticholinergic drugs, such as Ditropan… The post QOD 56: Treatment for Urinary Incontinence (GI/GU/Basic Care and Comfort) appeared first on NURSING.com.
Harrisons Online Update