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Exerting maximum influence on stakeholders, helping companies navigate regulatory complexity and promoting industry best practice are three big jobs that the UK consumer healthcare industry association, PAGB, has set itself for the next five years. In the last five years, PAGB has made significant headway with UK government, reports PAGB CEO Michelle Riddalls, establishing the economic and social value of self-care and ensuring that self-care is part of the UK's national healthcare strategy. Rx-to-OTC switch has been a major area of success, Michelle notes in this episode of the Over the Counter podcast. The Department of Health and Social Care recently published a list of switches it would like to see applications for, and PAGB is now facilitating members to take advantage of this opportunity. But there's always more work to be done. Switch involves significant risk, which PAGB is trying to reduce through further work with policy makers, and with a new government, the association must ensure that self-care remains high up on the agenda for politicians. Given the breadth of PAGB's work discussed by Michelle, we have split this episode into two, so watch out for the second part in two weeks' time on your favourite podcast provider and on Citeline's HBW Insight. Timestamps 2:10 – Introductions 2:40 – PAGB's new five-year strategy 5:40 – Evolution not revolution 8:00 – Self-care and UK government policy 10:30 – Quantifying the value of self-care 12:30 – Lobbying around AMR and OTCs 16:00 – Rx-to-OTC switch in the UK 24:00 – The power of brands Guest Bio Michelle Riddalls OBE is Chief Executive Officer of PAGB, the consumer healthcare association, which represents the manufacturers of branded over-the-counter (OTC) medicines, self-care medical devices and food supplements in the UK. Prior to joining PAGB, Michelle was Director of Regulatory Affairs for the Northern European Cluster at Pfizer Consumer Healthcare, where she was integral in the highly successful POM to GSL reclassification of Nexium Control and the Viagra Connect POM to P switch. Michelle has been recognised across a number of industry awards, including the Women in Trade Powerlist in 2024, and was awarded an OBE for outstanding services to consumer health in the King's 2025 New Year Honours.
Evolving with Nita Jain: Health | Science | Self-Improvement
In this episode of Evolving, Nita Jain talks with Richard Sprague, a software engineer, quantified self enthusiast, and co-founder of personal health tracking startups. Sprague discusses the complexities of the microbiome, the limitations of single-point microbiome testing, and the importance of longitudinal sampling.He shares insights from his extensive self-experimentation data collection, discussing fasting, probiotics, and the impact of alcohol on glucose levels. Sprague also touches on how personal science can empower individuals to optimize their health by tailoring approaches to fit their unique biological responses.The Journey into Personal ScienceRichard Sprague's journey into personal science began with his background in software engineering and an early fascination with computers. Observing the parallels between computer systems and human biology, he developed an interest in tracking genes and other biological markers. This led him to explore how personal experimentation can inform individual health insights—a theme central to the quantified self movement.Are We Human or Are We Computers?Sprague dives into the complexities of the human microbiome—an intricate system comprising trillions of microorganisms living in and on our bodies—and emphasizes that comparing the microbiome to a computer algorithm oversimplifies its complexity. The human microbiome is a dynamic system influenced by a myriad of factors, including genetics, environment, and lifestyle.Jain and Sprague discuss the challenges of microbiome testing and the importance of longitudinal sampling to capture a more accurate picture of the gut microbiome. Richard emphasizes that single-point microbiome tests can be misleading due to the natural diurnal variation and the inherent compositional problem in sampling.Promise & Pitfalls of Microbiome TestingOne of the key pitfalls in interpreting microbiome results is the variability introduced at multiple stages of microbiome testing, from sample collection to data processing. Sprague highlights the significance of working with the same lab using consistent protocols to ensure reliable results. He also emphasizes the importance of understanding that many factors can skew microbiome readings, leading to potentially misleading conclusions.The Power of Self-ExperimentationSprague introduces the concept of personal science, or n-of-one studies, where individuals engage in self-experimentation to find what works best for their unique biology. He shares insights from his own experiments with kombucha, probiotics, and dietary interventions like fasting, highlighting how these experiences have informed his understanding of his microbiome and overall health.Embracing Curiosity and MindfulnessSprague stresses the importance of maintaining curiosity and skepticism about health practices and recommendations and encourages listeners to be mindful of their own body and health, considering personal experimentation as a powerful tool for gaining insights and making informed decisions.Subscribe to the podcast at nitajain.com!Time Stamps00:00 Richard Sprague's Background00:45 Journey into Tech and Personal Science02:32 Complexity of Human Biochemistry vs. Computers05:24 Microbiome Testing and Its Challenges06:52 Pitfalls in Interpreting Microbiome Results16:57 Personal Science and Self-Experimentation25:06 The Impact of Microbiome on Health25:47 Personal Microbiome Discoveries27:19 Critical Windows for Microbiome Development28:00 Manipulating the Microbiome31:58 Microbiome and Disease Hypotheses36:25 Fasting and Microbiome Health39:11 Personal Science and Self-Experimentation45:17 Surprising Personal Experiment Results47:19 Conclusion and Final Thoughts Get full access to Evolving with Nita Jain at www.nitajain.com/subscribe
Israel Gasperin is a visionary entrepreneur, engineering scientist and the founder of Zentrela, a company dedicated to transforming cannabis research through advanced neurotechnology and AI. Under Israel's leadership, Zentrela developed the Psychoactive Effect Level (PEL) metric, an innovative EEG-based measure capable of objectively assessing cannabis products' psychoactive potency. By combining wearable EEG technology with AI-driven EEG analysis, the PEL metric provides cannabis producers, researchers, and regulators with a non-invasive and cost-effective way to quantify product effects and maintain quality control. At CannMed 25, Israel will share results from over 10,000 EEG scans of consumers using a wide range of cannabis products in his oral presentation titled “Cannabis Effect Research Driven by EEG Technology and Machine Learning”. During our conversation, we discuss: How Zentrela's wearable EEG technology got its start measuring drowsiness in truck drivers The unreliability of consumer feedback with regards to cannabis product effects How the PEL metric was created to measure the unique psychoactive effects of cannabis How producers can use PEL to objectively measure the quality and effectiveness of cannabis products beyond cannabinoid percentages Research findings that show THC% and PEL% are not directly correlated and more Thanks to This Episode's Sponsor: The DENT Institute With more than 300,000 patient visits per year, the DENT Neurologic Institute ranks among the largest neuroscience centers in North America. Its 24 subspecialty clinics often treat the most challenging neurologic conditions including but not limited to Migraine, Chronic pain, ALS, MS, Parkinson's, Dementia, and Neuro-Oncology. With their mission of advancing neuroscience, the Dent Institute established a cannabis clinic in 2016 to aid in the treatment of these chronic conditions seen throughout the institute. Learn more at dentinstitute.com Additional Resources Zentrela Website Israel Gasperin on LinkedIn Use of a Novel EEG-Based Objective Test, the Cognalyzer®, in Quantifying the Strength and Determining the Action Time of Cannabis Psychoactive Effects and Factors that May Influence Them Within an Observational Study Framework Sensitivity, Specificity and Accuracy of a Novel EEG-Based Objective Test, the Cognalyzer®, in Detecting Cannabis Psychoactive Effects Register for CannMed 25 Meet the CannMed 25 Speakers and Poster Presenters Review the Podcast CannMed Archive
Today on the Social-Engineer Podcast: The Security Awareness Series, Chris is joined by Roy Luongo. Roy is the Chief Information Security Officer for the United States Secret Service. He leads a team in the defense and information assurance of all USSS information systems and solutions. Prior to his current role he was the Director, Joint Mission Operations Center for Cyber Command, providing oversight of mission critical Cyber Operations infrastructures. He has also served as Chief, NSA Red Team and Technical Director for Interactive Operations for the NSA. Roy is a retired Army soldier with 20 years' service within the Intelligence and Cyber career fields. [March 17, 2025] 00:00 - Intro 00:17 - Intro Links: - Social-Engineer.com - http://www.social-engineer.com/ - Managed Voice Phishing - https://www.social-engineer.com/services/vishing-service/ - Managed Email Phishing - https://www.social-engineer.com/services/se-phishing-service/ - Adversarial Simulations - https://www.social-engineer.com/services/social-engineering-penetration-test/ - Social-Engineer channel on SLACK - https://social-engineering-hq.slack.com/ssb - CLUTCH - http://www.pro-rock.com/ - innocentlivesfoundation.org - http://www.innocentlivesfoundation.org/ 01:55 - Roy Luongo Intro 02:44 - The Path to CISO of the Secret Service 04:58 - Cybersecurity in Early Education 07:50 - The Entry Level Catch-22 12:24 - Quantifying Risk 14:27 - The Best Way Forward 16:51 - The Effects and Future of AI 20:06 - Understanding Your Needs 22:11 - Advise to Young Roy 24:56 - The Cost of Training 29:01 - Mentors - Ed Skoudis - Brigadier General Brian D. Vile - Shawn Turskey 29:55 - Lollipop Moments - TEDxToronto - Drew Dudley "Leading with Lollipops" 31:33 - Book Recommendations - Cybersecurity Canon - Rick Howard - Kingpin - Kevin Poulsen - Turn the Ship Around! - L. David Marquet 33:49 - Wrap Up & Outro - www.social-engineer.com - www.innocentlivesfoundation.org
Die Themen in den Wissensnachrichten: +++ Wer oft schlecht schläft, glaubt Verschwörungsmythen eher +++ Deutsche haben immer weniger Probleme mit Karies +++ Viele übertragen ihre politischen Sympathien auf ihre Helden +++**********Weiterführende Quellen zu dieser Folge:Investigating the link between sleep quality and belief in conspiracy theories, Journal of Health Psychology, 12.03.2025Institut der Deutschen Zahnärzte, Sechste Deutsche Mundgesundheitsstudie, 17.03.2025Who does Darth Vader vote for? Not the same party as Harry Potter, Political Science Research and Methods, 17.03.2025The unexpected reason firms should institute policies to remove email signatures: Quantifying human mortality costs of email signature-based reputation signaling, Sustainable Futures, (09) 2025The oral drug obeldesivir protects nonhuman primates against lethal Ebola virus infection, Science Advances, 14.03.2025Alle Quellen findet ihr hier.**********Ihr könnt uns auch auf diesen Kanälen folgen: TikTok auf&ab , TikTok wie_geht und Instagram .
In this episode we discuss 4 articles that changed our practice. Listen to us talk through real cases, what we used to do, and what we do now. Quantifying a potential protective effect of buprenorphine on fatality risk during acute fentanyl exposures. Journal of Substance Use and Addiction Treatment, Volume 158, 2024. 209252, ISSN 2949-8759. Outcomes After Initiation of Medications for Alcohol Use Disorder at Hospital Discharge. JAMA Netw Open. 2024 Mar 4;7(3):e243387. Association of Cannabis Use With Cardiovascular Outcomes Among US Adults. J Am Heart Assoc. 2024 Mar 5;13(5):e030178. Association of random and observed urine drug screening with long-term retention in opioid treatment programs. Drug Alcohol Depend. 2024 Feb 1;255:111067. --- ASAM Advocacy Center --- This podcast offers category 1 and MATE-ACT CME credits through MI CARES and Michigan State University. To get credit for this episode and others, go to this link to make your account, take a brief quiz, and claim your credit. To learn more about opportunities in addiction medicine, visit MI CARES. CME: https://micaresed.org/courses/podcast-addiction-medicine-journal-club/ --- Original theme music: composed and performed by Benjamin Kennedy Audio editing: Michael Bonanno Executive producer: Dr. Patrick Beeman A podcast from Ars Longa Media --- This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice. The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. Email: addictionmedicinejournalclub@gmail.com Facebook: @AddictionMedJC Facebook Group: Addiction Medicine Journal Club Instagram: @AddictionMedJC Threads: @AddictionMedJC YouTube: addictionmedicinejournalclub Twitter/X: @AddictionMedJC Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities. Learn more about your ad choices. Visit megaphone.fm/adchoices
Who will "save" your soul? Can the human soul be transferred onto a computer chip? According to our hyper-materialist "science", this may not only be possible, but the technological procedure for achieving immortality by transplanting the human soul onto an electronic chip was introduced in 2004 and the patent for it finally granted in 2009...Reading from "Method of Recording and Saving of Human Soul for Human Immortality and Installation for it" Patent Application, submitted by Alexander Bolonkin...www.alchemicaltechrevolution.com
“Ardor and diligence”: Quantifying the faculty effort needed in emergency medicine graduate medical education by SAEM
“Ardor and diligence”: Quantifying the faculty effort needed in emergency medicine graduate medical education by SAEM
Iron Culture is officially part of the 3-plate club. In this episode of Iron Culture, hosts Eric Trexler and Eric Helms celebrate their milestone 315th episode while diving into various topics including testosterone replacement therapy (TRT), the efficacy of citrulline malate, training techniques for hypertrophy, managing tendinopathy, the health benefits of coffee, and programming for individuals with obesity. They also discuss how to improve training intensity and the importance of enthusiasm in lifting. Time stamps: 0:00 Introduction to another addition of Iron Culture 1:35 See the entire MASS team speak at the Sports Nutrition Association Annual Conference https://sportsnutritionassociation.com/sna-annual-2025-conference/ 5:55 Questions about testosterone replacement therapy Iron Culture Ep. 136- All About Testosterone & TRT (Yeah We Go There) https://www.youtube.com/watch?v=U5PDtstlmJ0 Tang Fui 2017 The effects of testosterone on body composition in obese men are not sustained after cessation of testosterone treatment https://pubmed.ncbi.nlm.nih.gov/28561278/ 20:42 An update on citrulline malate 30:18 Quantifying volume of time-saving techniques Coleman 2022 Muscular Adaptations in Drop Set vs. Traditional Training: A meta-analysis https://journal.iusca.org/index.php/Journal/article/view/135 Sødal 2023 Effects of Drop Sets on Skeletal Muscle Hypertrophy: A Systematic Review and Meta-analysis https://pubmed.ncbi.nlm.nih.gov/37523092/ 34:09 Eric's tips for working around tendinopathy 40:43 Is caffeine bad for teeth and substituting coffee for decaf? 47:31 Hip flexion training for rectus femoris hypertrophy 49:35 Resistance training prescription for people with obesity trying to lose weight 56:24 Defining and increasing training intensity 1:00:46 Training Hard Versus Training Smart
I keep hearing data product, data strategy, and UX teams often struggle to quantify the value of their work. Whether it's as a team as a whole or on a specific data product initiative, the underlying problem is the same – your contribution is indirect, so it's harder to measure. Even worse, your stakeholders want to know if your work is creating an impact and value, but because you can't easily put numbers on it, valuation spirals into a messy problem. The messy part of this valuation problem is what today's episode is all about—not math! Value is largely subjective, not objective, and I think this is partly why analytical teams may struggle with this. To improve at how you estimate the value of your data products, you need to leverage other skills—and stop approaching this as a math problem. As a consulting product designer, estimating value when it's indirect is something that I've dealt with my entire career. It's not a skill learned overnight, and it's one you will need to keep developing over time—but the basic concepts are simple. I hope you'll find some value in applying these along with your other frameworks and tools. Highlights/ Skip to Value is subjective, not objective (5:01) Measurability does not necessarily mean valuable (6:36) Businesses are made up of humans. Most b2b stakeholders aren't spending their own money when making business decisions—what does that mean for your work? (9:30) Quantifying a data product's value starts with understanding what is worth measuring in the eye of the beholder(s)—not math calculations (13:44) The more difficult it is to show the value of your product (or team) in numbers, the lower that value is to the stakeholder—initially (16:46) By simply helping a stakeholder to think through how value should be calculated on a data product, you're likely already providing additional value (18:02) Focus on expressing estimated value via a range versus a single number (19:36) Measurement of anything requires that we can observe the phenomenon first—but many stakeholders won't be able to cite these phenomena without [your!] help (22:16) When you are measuring quantitative aspects of value, remember that measurement is not the same as accuracy (precision)—and the precision game can become a trap (25:37) How to measure anything—and why estimates often trump accuracy (31:19) Why you may need to steer the conversation away from ROI calculations in the short term (35:00) Quotes from Today's Episode Even when you can easily assign a dollar value to the data product you're building, that does not necessarily reflect what your stakeholder actually feels about it—or your team's contribution. So, why do they keep asking you to quantify the value of your work? By actually understanding what a shareholder needs to observe for them to know progress has been made on their initiative or data product, you will be positioned to deliver results they actually care about. While most of the time, you should be able to show some obvious economic value in the work you're doing, you may be getting hounded about this because you're not meeting the often unstated qualitative goals. If you can surface the qualitative goals of your stakeholder, then the perception of the value of your team and its work goes up, and you'll spend less time trying to measure an indirect contribution in quant terms that only has a subjectively right answer. (6:50) The more difficult it is for you to show the monetary value of your data product (or team), the lower that value likely is to the stakeholder. This does not mean the value of your work is “low.” It means it's perceived as low because it cannot be easily quantified in a way that is observable to the person whose judgment matters. By understanding the personal motivations and interests of your stakeholders, you can begin to collaboratively figure out what the correct success metrics should be—and how they'd be measured. By just simply beginning to ask and uncover what they're trying to measure, you can start to increase your contributions' perceived value. (17:01) Think about expressing “indirect value” as a range, not a precise single value. It's much easier to refine your estimate (if necessary) once a range has been defined, and you only need to get precise enough for your stakeholder to make a decision with the information. How much time should you spend refining your measurement of the value? Potentially little to none—if the “better math” isn't going to change anyone's mind or decision. Spending more time to measure a data product's value more accurately takes you away from doing actual product work—and if there isn't much obvious value to the work, maybe the work—not the measurement of the work—needs to change. (19:49) Smart leaders know that deriving a simple calculation of indirect contributions is complex—otherwise, the topic wouldn't keep coming up. There is a “why” behind why they're asking, and when you understand the “why,” you'll be better positioned to deliver the value they actually seek, using valuation measurements that are “just enough” in their precision. What do you think it says to a stakeholder if you're spending an inordinate amount of time simply trying to calculate and explain the value of your data product? (23:22) Many organizations for years have invested in things that don't always have a short term ROI. They know that ROI takes time, and they can't really measure what it's worth along the way. Examples include investments in company culture, innovation, brand reputation, and many others. If you're constantly playing defense and having to justify your existence or methods by quantifying the financial value of your data products (or data product management team, or UX team, or any other indirect contributor/contribution), then either your work truly does lack value, or you haven't surfaced what the actual success metrics and outcomes are— in the eyes of the stakeholder. As such, the perceived value is “low” or opaque. They might be looking for a hard number to assign to it because they're not seeing any of the other forms of value that they care about that would indicate positive progress. It's easier to write [you] a large check for a big, innovative, unproven initiative if your stakeholders know what you and your team can accomplish with a small check. (35:16) Links Experiencing Data: Episode 80 with Doug Hubbard
Derek Moore revisits the 1994-95 interest rate and market environment against the current backdrop regarding treasury yields and future S&P 500 Index returns. Plus, going through the case for higher for longer, whether that is good or bad for markets, and the adjustment the market would need to go through. Later, quantifying how sensitive the S&P 500 Index is to change in the forward PE ratio by putting into actual numbers and levels. Also, looking at Arista Networks and Alibaba before earnings and what the options market is saying their expected one standard deviation moves might be up or down. Finally, most people look at Real Inflation adjusted GDP, but Nominal GDP growth may be correlated to the 10-year yield and what that means if we go back to pre-GFC nominal growth rates. All this and more. What is Nominal GDP Growth Rate? What is Real GDP growth? The US Dollar index and whether we are out of the zone of significance yet? Inflation in services remains sticky Why interest rates staying higher isn't necessarily a problem for the stock market Quantifying sensitivity of the S&P 500 Index to small changes in the forward PE multiple 1994-95 vs 2024-25 update around treasury yields, S&P 500 returns Alibaba and Arista earnings this week and their option implied moves How to calculate expected move around earnings based on implied volatility levels Mentioned in this Episode Derek Moore's book Broken Pie Chart https://amzn.to/3S8ADNT Jay Pestrichelli's book Buy and Hedge https://amzn.to/3jQYgMt Derek's book on public speaking Effortless Public Speaking https://amzn.to/3hL1Mag Contact Derek derek.moore@zegainvestments.com
Last year was the first calendar year with a global mean temperature of more than 1.5°C above the 1850-1900 average. Since 90% of global warming is occurring in the ocean, due to the earth's rising energy imbalance resulting from continuing and increasing GHG emissions, not surprisingly research published in “Environmental Research Letters” in late January concluded ocean temperatures for the 450 day period between April '23 and July '24 were the warmest ever. Ocean surface temperatures are now warming 40 times faster than 40 years ago. As I've noted in previous discussions with Prof. Abraham, because warming oceans/ocean heat content plays a fundamental role in our planet's energy, water and carbon cycles, warming ocean temperatures disrupt marine life that substantially threaten the availability of food we eat and the oxygen we breathe.The “Environmental Research Letters” article, “Quantifying the Acceleration of Muti-decadal Global Sea Surface Warming Driven by Earth's Energy Imbalance,” is at: https://iopscience.iop.org/article/10.1088/1748-9326/adaa8a/pdf. This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.thehealthcarepolicypodcast.com
If you have a company that strives to be, in their own words, “Kind to one's tastebuds, body, and the world” -- can you tease out when it pays to be kind, and what you do when you have to assess that mission pragmatically? What about when you bring that novel supply chain to market. What works in the market, and how does it shape your path to getting there? In today's episode, we look at the balancing act between Business and Social Good with Kind Snacks Founder Daniel Lubetzky. Special Guest: Daniel Lubetzky.
Welcome to Strategy Skills episode 525, an interview with the authors of The ROI of Thought Leadership: Calculating the Value that Sets Organizations Apart, Cindy Anderson and Anthony Marshall. In this episode, Cindy and Anthony discuss how their work at IBM shaped their understanding of thought leadership's value in building client relationships and explain the quantifiable benefits of thought leadership. They also address how AI is impacting thought leadership creation and consumption, and the distinction between thought leadership and sales content. They stress the need for independent, data-driven content to build trust and relationships, not for direct sales. Their insights stem from decades of combined experience at organizations like the Project Management Institute and IBM's Institute for Business Value. Cindy Anderson is the Chief Marketing Officer/Global Lead for Engagement & Eminence at the IBM Institute for Business Value. Anthony Marshall is the Chair of the Board of Advisors for The Global Thought Leadership Institute at APQC and the Senior Research Director of thought leadership at the IBM Institute for Business Value. Get The ROI of Thought Leadership here: https://rb.gy/3vv7wm Here are some free gifts for you: Overall Approach Used in Well-Managed Strategy Studies free download: www.firmsconsulting.com/OverallApproach McKinsey & BCG winning resume free download: www.firmsconsulting.com/resumepdf Enjoying this episode? Get access to sample advanced training episodes here: www.firmsconsulting.com/promo
TUNE IN TO LEARN: This episode focuses on the powerful concept of urgency and its critical importance in driving change in both personal and business contexts. As one great book says, If it's not urgent, it doesn't get done. We explore the barriers to change, and strategies for "training" urgency to overcome them. • Understanding the high failure rate of change initiatives due to lack of urgency • The distinction between coaching's focus on measurable results versus therapy's emphasis on understanding • Comfort zones and the resistance to change and the most important question to get you unstuck • Quantifying the cost of waiting to create a sense of urgency • The necessity of genuine time-sensitive opportunities to motivate action • The impact of personal stakes and accountability in goal achievement • The value of quick wins to maintain momentum in progress ... Please do share this podcast with one another to keep each other accountable on the goals you say are important. Create this sense of urgency for yourself and the people around you. If you're okay with never having what you say you want, then that's fine with me. But is it fine with you? Text Me Your Thoughts and IdeasSupport the show Brought to you by Angela Shurina EXECUTIVE HEALTH AND OPTIMAL PERFORMANCE COACH Change in days - not in years!
In Episode 10, of Season 5 of Driven by Data: The Podcast, Kyle Winterbottom is joined by Peter Everill, AI, ML & Data Product Leader for a European Retailer for a LinkedIn Live event, and they discuss the importance of quantifying value, in which they talk about:How data can significantly impact P&L performanceWhy the USP of the data team lies in identifying where to focus and what action to takeThe importance of metrics in making performance observable and driving decisionsThe risk of internal data teams falling behind without a structured consultancy methodologyHow improving business literacy in data teams helps focus on the right metricsThe role of methodology in influencing P&L outcomesWhy winning over senior management is crucial for successThe need for metrics that drive actionable insights and business performanceWhy not everyone wants to be data-driven—and how to choose the right sponsorsThe cultural adoption of metrics and its impact on business successUnderstanding failure states to identify areas for improvementHow collaboration between data teams and business stakeholders drives better outcomesWhy data literacy shouldn't be a burden on business usersThe common gap in business process mapping within organisationsWhy engaging finance teams is essential for understanding P&L impactThe importance of quick wins in gaining stakeholder supportWhy cultural openness to data is necessary for effective implementationWhy actionable, role-specific metrics lead to better business adoptionThanks to our sponsor, Data Literacy Academy.Data Literacy Academy is leading the way in transforming enterprise workforces with data literacy across the organisation, through a combination of change management and education. In today's data-centric world, being data literate is no longer a luxury, it's a necessity.If you want successful data product adoption, and to keep driving innovation within your business, you need to start with data literacy first.At Data Literacy Academy, we don't just teach data skills. We empower individuals and teams to think critically, analyse effectively, and make decisions confidently based on data. We're bridging the gap between business and data teams, so they can all work towards aligned outcomes.From those taking their first steps in data literacy to seasoned experts looking to fine-tune their skills, our data experts provide tailored classes for every stage. But it's not just learning tracks that we offer. We embed a deep data culture shift through a transformative change management programme.We take a people-first approach, working closely with your executive team to win the hearts and minds. We know this will drive the company-wide impact that data teams want to achieve.Get in touch and find out how you can unlock the full potential of data in your organisation. Learn more at www.dl-academy.com.
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Welcome to PsychEd, the psychiatry podcast for medical learners, by medical learners. This episode covers ADHD in youth with Dr. Daniel Gorman, an Associate Professor in the Department of Psychiatry at the University of Toronto and a Staff Psychiatrist at The Hospital for Sick Children. Dr Gorman's clinical and academic interests include ADHD, Tourette syndrome, obsessive-compulsive disorder, child psychopharmacology, psychiatric education, and narrative medicine. He is highly involved in resident teaching and clinical supervision, and from 2014 to 2022 he was the Program Director for the Child and Adolescent Psychiatry subspecialty program at the University of Toronto. Dr. Gorman has given over 85 invited presentations and authored or co-authored over 35 peer-reviewed articles and book chapters, mainly related to childhood neuropsychiatric disorders and their pharmacological management. He also contributed to several Canadian guidelines, including guidelines on cardiac risk assessment before the use of stimulants, management of tic disorders, pharmacotherapy for childhood disruptive and aggressive behaviour, and pharmacogenetic testing for children treated with psychiatric medications. The learning objectives for this episode are as follows: By the end of this episode, the listener will be able to… Review diagnostic criteria for ADHD Describe important considerations in making the diagnosis of ADHD Describe psychosocial aspects of management of ADHD Outline the pharmacological management of ADHD Guest: Dr. Daniel Gorman Hosts: Dr. Kate Braithwaite, Dr. Shaoyuan Wang (PGY-4), Matthew Cho (MS-4) Audio editing by: Dr. Angad Singh (PGY-1) Resources: CADDRA - Canadian ADHD Resource Alliance: Canadian ADHD Practice Guidelines, 4.1 Edition, Toronto ON; CADDRA, 2020. References: American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). https://doi.org/10.1176/appi.books.9780890425596 Biederman, J., DiSalvo, M., Fried, R., Woodworth, K. Y., Biederman, I., & Faraone, S. V. (2019). Quantifying the protective effects of stimulants on functional outcomes in attention-deficit/hyperactivity disorder: A focus on number needed to treat statistic and sex effects. Journal of Adolescent Health, 65(6), 784–789. https://doi.org/10.1016/j.jadohealth.2019.06.016 Peterson, B. S., Trampush, J., Brown, M., Maglione, M., Bolshakova, M., Rozelle, M., Miles, J., Pakdaman, S., Yagyu, S., Motala, A., & Hempel, S. (2024). Tools for the diagnosis of ADHD in children and adolescents: A systematic review. Pediatrics, 153(4), e2024065854. https://doi.org/10.1542/peds.2024-065854 Fedder, D., Patel, H., & Saadabadi, A. (2018). Atomoxetine. StatPearls. Retrieved January 31, 2025, from https://www.ncbi.nlm.nih.gov/books/NBK493234/ Canadian Pediatric Society. (2022). Mental health: Screening tools and rating scales. Canadian Pediatric Society. Retrieved January 31, 2025, from https://cps.ca/mental-health-screening-tools For more PsychEd, follow us on Instagram (@psyched.podcast), X (@psychedpodcast), and Facebook (PsychEd Podcast). You can provide feedback by email at psychedpodcast@gmail.com. For more information, visit our website at psychedpodcast.org.
Episode: 2418 Quantifying the chance of losing at casino games. Today, luck and Las Vegas.
On Wednesday January 22, Fidelity Investments Canada hosted VISION 2025 Toronto, a full-day event connecting Fidelity's portfolio managers and experts with thousands of advisors joining both in-person and virtually across the country. For today's podcast we're bringing you the second session of the day, featuring Neil Constable, Head of Quantitative Research and Investments. Neil speaks with moderator Glen Davidson about his career path, trends and quantitative research and how his large team operates, and introduces new Fidelity Canada products launching on January 28. Advisors can watch full video replays of the event and qualify for CE Credits. Please visit fidelity.ca or reach out to your wholesaler for more information. At Fidelity, our mission is to build a better future for Canadian investors and help them stay ahead. We offer investors and institutions a range of innovative and trusted investment portfolios to help them reach their financial and life goals. Fidelity mutual funds and ETFs are available by working with a financial advisor or through an online brokerage account. Visit fidelity.ca/howtobuy for more information. For a fourth year in a row, FidelityConnects by Fidelity Investments Canada was ranked #1 podcast by Canadian financial advisors in the 2024 Environics' Advisor Digital Experience Study.
On this week's episode of The RAG Podcast, I am joined by Hemish Ilangaratne, founder of RX Group, a specialist life sciences recruitment agency.In this candid episode, Hemish sheds light on his inspiring journey: From 11 years at S3 Group (where he didn't close a single deal in the last seven years) to launching RX Group in 2023.Exceeding his modest first-year goal of £150k and reaching nearly £1M in revenue within two years.How self-doubt and perseverance shaped his decision to become an entrepreneur.Building a successful life sciences recruitment business serving clients across the US.The role of personal branding, LinkedIn, and a supportive partner in his rapid growth.Insights on leadership, team-building, and creating a positive impact in a niche market.Hemish's story is a testament to resilience, strategy, and the power of believing in yourself – even when doubt creeps in. If you're considering launching your own business or want to learn how to thrive in 2025, this episode is for you!---------------------------------------------------------------------------------Chapters00:00 Introduction to Hemish Ilangaratne and RX Group06:49 Career development at S312:26 Transitioning to management roles17:58 Challenges in leadership and team management21:01 The decision to start RX Group25:19 Navigating family expectations and career choices29:49 Transitioning to entrepreneurship32:38 Starting the journey34:04 Building a personal brand35:58 Leveraging LinkedIn for success37:30 Quantifying revenue growth39:54 The importance of leadership41:21 Balancing work and personal life43:17 Enjoying independence in business45:29 Future growth plans47:53 Hiring strategies and team dynamics49:19 Creating a meaningful impact51:54 The bigger picture of business goals53:27 Attracting talent in a niche market55:31 Building confidence before quitting---------------------------------------------------------------------------------Episode Sponsor: Beyond the Founder.What is the essential senior hire you need to make to increase revenue and protect your recruitment business as it grows? Let's be honest, building and scaling an agency isn't just about billing more. It's about putting together a leadership team that you trust to help you take your business to the next level. That's where Beyond the Founder comes in. They specialise in placing leaders who make an impact – whether it's a Managing Director to shape your vision, a Sales leader to boost revenue, or an Ops expert to streamline your processes. Their no-nonsense, tailored approach is designed to save ambitious recruitment founders time and to deliver results.Paul, the man behind Beyond the Founder, has over 20 years of experience scaling recruitment businesses himself, so he understands what's at stake for his clients. What Paul and his team do so well is relieve that pressure. They help you remove your biggest obstacle to growth: finding and securing your key hires. And they do it in a way that supports your long-term business goals. So, if you're serious about growing your recruitment agency or if you want to build a business that...
Episode 123 - Cadence Drills, Heart Rate Fluctuations, and Quantifying Stress Hello everyone. Welcome to the latest episode of The Matchbox Podcast powered by Ignition Coach Co. I'm your host, Adam Saban, and on this week's episode we're talking cadence drills, heart rate fluctuations, and quantifying stress. As always, if you like what you hear please share this with your friends and leave us a five star review and if you have any questions for the show drop us an email at matchboxpod@gmail.com with email title The Matchbox Podcast or head over to ignitioncoachco.com and fill out The Matchbox Podcast listener question form. Alight let's get into it! For more social media content, follow along @ignitioncoachco @adamsaban6 @dizzle_dillman @dylanjawnson @kait.maddox https://www.youtube.com/c/DylanJohnsonCycling https://www.ignitioncoachco.com https://www.youtube.com/@DrewDillmanChannel Intro/ Outro music by AlexGrohl - song "King Around Here" - https://pixabay.com/music/id-15045/ The following was generated using Riverside.fm AI technologies Keywords cycling, pedaling drills, heart rate, training adaptations, lactate testing, cycling performance, endurance training, VO2 max, anaerobic sessions, cycling fitness, lactate levels, training stress, recovery, VO2 max, training metrics, subjective training, lactate testing, athlete performance, endurance training, fitness goals Summary In this episode, the hosts discuss various aspects of cycling training, focusing on pedaling drills, heart rate changes with increased training volume, and the use of lactate testing to measure workout intensity. They explore the effectiveness of different pedaling techniques, the implications of heart rate variations, and how to assess the stress of high-intensity sessions. In this conversation, the hosts delve into the complexities of lactate levels and their relationship to training stress, emphasizing that the increase in stress is not linear. They discuss the importance of recovery, especially for older athletes, and the need to listen to one's body rather than relying solely on objective metrics. The practicality of lactate testing is questioned, with the consensus that while it can provide useful information, it may not be worth the hassle for most athletes. The conversation concludes with encouragement for athletes to focus on their training and recovery, especially in light of personal challenges. Takeaways Zone two riding may not be effective without specific drills. High and low cadence training can be beneficial for certain events. Research on cadence training shows mixed results. Single leg drills can help identify muscular imbalances. Preferred cadence varies by cycling discipline. Heart rate can decrease with increased training volume. A decline in heart rate can indicate improved fitness. Lactate testing can provide insights into workout stress. Intensity sessions should be tailored to individual recovery. Understanding lactate levels can help manage training loads. Lactate levels vary among individuals and are not a strict measure of stress. Recovery is crucial, especially for older athletes. Training should balance subjective feelings and objective metrics. Lactate testing can be cumbersome and may not provide significant benefits. Listening to your body is essential for effective training. VO2 max sessions can be more stressful than longer endurance rides. Athletes should focus on their overall training volume and recovery. Subjective experiences can often contradict objective data. It's important to adjust training intensity based on how one feels. Overcoming personal challenges can lead to significant fitness gains. Titles Exploring the Effectiveness of Pedaling Drills Understanding Heart Rate Changes in Cyclists The Role of Lactate Testing in Cycling Performance Maximizing Cycling Efficiency Through Cadence Training Sound Bites "Zone two riding is a waste of time." "I think there is a purpose for everything." "Stress increases exponentially, not linearly." "You need to be aware of your body." "Recovery should be his main focus." "Sometimes training requires subjectivity." "Training is very subjective." "Lactate testing is a pain in the ass." "Lactate checking is too much of a headache." Chapters 00:00 Introduction and Pedaling Drills Discussion 16:47 Heart Rate Changes and Training Adaptations 20:10 Lactate Testing and Intensity Session Stress 22:35 Understanding Lactate Levels and Stress Response 28:28 The Importance of Recovery in Training 34:57 Subjectivity vs. Objectivity in Training Metrics 40:40 The Practicality of Lactate Testing 45:36 Encouragement and Future Outlook for Athletes
Joseph James, biologist at the U.S. Environmental Protection Agency, discusses his career trajectory and the creation of Binning Singletons, a unique mentorship program built on peer-to-peer networking at scientific meetings and conferences and was first implemented in 2019 at ASM Microbe. Links for the Episode Binning Singletons and Peer-to-Peer Networking Learn more about Binning Singletons. Contact Joe James: Joe@binningsingleton.com Follow Binning Singletons on Bluesky. Binning Singletons: Mentoring through Networking at ASM Microbe 2019—mSphere article. Binning Singletons: Tackling Conference Networking When You Don't Know Anyone—Guest post on Addgene Blog. Mastering a Mentoring Relationship as the Mentee—asm.org article that James says has really helped him explain Binning Singletons as a coaching form of mentorship. Mapping a Mentoring Roadmap and Developing a Supportive Network for Strategic Career Advancement—article on developing networks of mentors, another area Binning Singletons tries to address. #FEMSmicroBlog: Networking at Online Conferences (for Early Career Scientists). Take the MTM listener survey! James' Research Dietary lead modulates the mouse intestinal microbiome: Subacute exposure to lead acetate and lead contaminated soil. In situ differences in nitrogen cycling related to presence of submerged aquatic vegetation in a Gulf of Mexico estuary. Quantifying stream periphyton assemblage responses to nutrient amendments with a molecular approach. Analysis of Bacterial Communities in Seagrass Bed Sediments by Double-Gradient Denaturing Gradient Gel Electrophoresis of PCR-Amplified 16S rRNA Genes. Use of composite data sets for source-tracking enterococci in the water column and shoreline interstitial waters on Pensacola Beach, Florida.
Part 2 with Hall of Famer, Kurt Hester! Kurt is a legend in the S&C field, hes been in the field since 1995 and has worked at the top levels in the collegiate and private sector. Currently Kurt works at Lousiana Tech as a Director of Football Sports Performance where he has been for the last 11 years. Prior to that Kurt opened a private training facility working with up to 500 clients per day as well as stints at LSU and Tulane University. A wealth of knowledge from a guy thats been there, done it and got a few t-shirts! If you missed it, check out Part 1 00:00 Tracking Data & Quantifying the Job 05:55 How to organise the complexities in top level College Football 07:50 Tackling drills 10:25 Using tempo variations to train mechanics of movement 16:45 Coaches eye - best way to measure? 20:25 Reaction based drills 24:55 Kurts conversation with Bondarchuk 28:15 Where was Kurt happiest? 34:25 The best job in College S&C?!
Is quantum computing the next big thing? This week, Autonomous Technology and Robotics Director of Research Sam Korus and Associate Portfolio Manager Nick Grous are joined by ARK Chief Futurist Brett Winton to discuss the latest advancements in quantum computing and AI drug discovery. They discuss Google's recent quantum chip announcement, the challenges of scaling quantum technology, and the potential applications in drug discovery. The conversation shifts to the partnership between GlaxoSmithKline and Relation Therapeutics, highlighting the promise of AI in revolutionizing drug development processes, reducing costs, and improving efficiency. The episode concludes with insights on the future of drug development and the potential for significant market changes in the pharmaceutical industry.If you know ARK, then you probably know about our long-term research projections, like estimating where we will be 5-10 years from now! But just because we are long-term investors, doesn't mean we don't have strong views and opinions on breaking news. In fact, we discuss and debate this every day. So now we're sharing some of these internal discussions with you in our new video series, “The Brainstorm”, a co-production from ARK and Public.com. Tune in every week as we react to the latest in innovation. Here and there we'll be joined by special guests, but ultimately this is our chance to join the conversation and share ARK's quick takes on what's going on in tech today.Key Points From This Episode:Quantum computing is still 15 years away from commercial viability.AI is transforming drug discovery, making it faster and cheaper.AI drug discovery could reduce development costs to $600 million.The future of healthcare may focus on curing diseases rather than just treating them.For more updates on Public.com:Website: https://public.com/YouTube: @publicinvestTwitter: https://twitter.com/public
Cecelia Koetting, OD, FAAO, Dipl ABO, closes out The MOD Pod's last episode of 2025 with a discussion on aberrations in refractive cataract surgery with Nick Bruns, OD, FAAO. With modern technology, Dr. Bruns emphasizes that understanding the effect of higher-order aberrations helps optometrists better achieve optimal outcomes. Listen to the episode now.
Today, I'm joined by Cesar Carvalho, co-founder & CEO of Wellhub. Formerly known as Gympass, Wellhub helps employees feel healthy and engaged at work with its corporate wellness platform spanning fitness, mental health, nutrition, and sleep solutions. In this episode, we discuss the company's evolution. We also cover: • Executing a successful rebrand • Quantifying the benefits of corporate wellness • Expanding its partner network from gyms and studios to include holistic well-being Subscribe to the podcast → insider.fitt.co/podcast Subscribe to our newsletter → insider.fitt.co/subscribe Follow us on LinkedIn → linkedin.com/company/fittinsider Wellhub's Website: https://wellhub.com/en-us/ Wellhub's LinkedIn: https://www.linkedin.com/company/wellhub/ Wellhub's IG: https://www.instagram.com/wellhub/ - The Fitt Insider Podcast is brought to you by EGYM. Visit EGYM.com to learn more about its smart workout solutions for fitness and health facilities. Fitt Talent: https://talent.fitt.co/ Consulting: https://consulting.fitt.co/ Investments: https://capital.fitt.co/ Chapters: (00:00) Introduction (01:51) Building a Corporate Wellness Ecosystem (06:11) Holistic Wellness and Future Trends (13:20) Quantifying the Benefits of Wellness Programs (17:14) The Flywheel Effect in Corporate Wellness (24:03) Focus and Future of Wellhub (32:32) Conclusion
Are hectic schedules leaving you stretched too thin? In this episode, Tiffany shares a real-time look at how she's navigating her busiest season yet. From redesigning her mornings to streamlining her priorities, Tiffany discusses her actionable strategies to reclaim time and make life more manageable. She highlights the importance of consistency, making intentional decisions, and setting boundaries to ensure her own well-being while managing a full house and a packed schedule. Sign up for Tiffany's newsletter for more tips and strategies like this. Timestamps: (00:00) Intro (01:30) The challenges of navigating multiple family commitments (05:17) Personal adjustments for consistency (10:30) Quantifying time to make smarter decisions
Dr Cynthia Schuck-Paim is the Scientific Director of the Welfare Footprint Project, a scientific effort to quantify animal welfare to inform practice, policy, investing and purchasing decisions. You can find links and a transcript at www.hearthisidea.com/episodes/schuck. We discuss: How to begin thinking about quantifying animal experiences in a cross-comparable way Whether the ability to feel pain is unique to big brained animals, or more widespread in the tree of life How fish farming compares to poultry and livestock farming How worried to be about bird flu zoonosis Whether different animal species experience time differently Whether positive experiences like joy could make life worth living for some farmed animals How animal welfare advocates can learn from anti-corruption nonprofits You can get in touch through our website or on Twitter. Consider leaving us an honest review wherever you're listening to this — it's the best way to support the show. Thanks for listening!
41-50. Round-Up Quick summaries of our last 10 (actually 11) articles. 41. Electronic Nicotine-Delivery Systems for Smoking Cessation 42. Quantifying a potential protective effect of buprenorphine on fatality risk during acute fentanyl exposures 43. Outcomes After Initiation of Medications for Alcohol Use Disorder at Hospital Discharge 44 Association of Cannabis Use With Cardiovascular Outcomes Among US Adults 45. Association of random and observed urine drug screening with long-term retention in opioid treatment programs 46. Smoking Cessation After Initial Treatment Failure With Varenicline or Nicotine Replacement: A Randomized Clinical Trial 47. Extended-Release Injection vs Sublingual Buprenorphine for Opioid Use Disorder With Fentanyl Use: A Post Hoc Analysis of a Randomized Clinical Trial 48. Associations of semaglutide with incidence and recurrence of alcohol use disorder in real-world population 49. Extended observation of reduced methamphetamine use with combined naltrexone plus bupropion in the ADAPT-2 trial 50. Kratom use as more than a "self-treatment" Prevalence of Kratom Use Disorder Among Kratom Consumers Long-term buprenorphine treatment for kratom use disorder: A case series --- Original theme music: composed and performed by Benjamin Kennedy Audio editing: Michael Bonanno Executive producer: Dr. Patrick Beeman A podcast from Ars Longa Media --- This is Addiction Medicine Journal Club with Dr. Sonya Del Tredici and Dr. John Keenan. We practice addiction medicine and primary care, and we believe that addiction is a disease that can be treated. This podcast reviews current articles to help you stay up to date with research that you can use in your addiction medicine practice. The best part of any journal club is the conversation. Send us your comments on social media or join our Facebook group. Email: addictionmedicinejournalclub@gmail.com Facebook: @AddictionMedJC Facebook Group: Addiction Medicine Journal Club Instagram: @AddictionMedJC Threads: @AddictionMedJC YouTube: addictionmedicinejournalclub Twitter/X: @AddictionMedJC Addiction Medicine Journal Club is intended for educational purposes only and should not be considered medical advice. The views expressed here are our own and do not necessarily reflect those of our employers or the authors of the articles we review. All patient information has been modified to protect their identities.
Join us as we sit down with Jordan Kaye, the Head of Technology at Belvedere Trading, to unpack the true nature of technical debt and its broader implications. In this episode, we delve into the delicate balance between managing tech debt and delivering business value, the impact of evolving technology on past decisions, and practical ways to enhance efficiency without compromising quality. Discover how to achieve flexibility and velocity in Agile development, the importance of intentional, business-aligned decisions, and the benefits of high team autonomy. Jordan shares his unique perspectives on quantifying and visualizing technical debt, effective project scoping, and conscious management. Gain valuable insights into navigating the complex landscape of tech debt and technological evolution. Don't forget to like, subscribe, and share this insightful conversation with your network. Highlights: 01:29 Defining Technical Debt 04:00 Quantifying and Managing Tech Debt 06:23 Tech Debt in Different Departments 09:06 The Evolution of Technology and Tech Debt 13:04 Balancing Business Needs and Engineering Discretion 13:58 The Challenge of Replicating Success 14:15 Conscious Decision-Making in Engineering 15:12 The Pareto Principle in Engineering 15:54 Empowering Teams with Business Understanding 18:09 Flexibility Over Correctness 19:47 The Art of Balancing Quality and Speed 21:23 Avoiding Premature Problem Solving 24:00 Just-in-Time Scoping Guest:
Learn more about the Delight Factor, a quantitative measurement, that scores a workplace on how it makes people feel—complementing measures like cost per square foot with a building's experiential qualities.
My guest is Stefan Thurner, A Professor of theoretical physics, and the President of the Complexity Science Hub in Vienna. Stefan has published over 240 scientific articles and he was elected Austrian Scientist of the Year 2017. He is also an external professor at the Santa Fe Institute. In our conversation, we first delve into the scaling laws of everything. We explore social, financial, biological, and economic dynamics—for example, how to make the economy more resilient by targeting some unique companies, how social bubbles form, the strength of networks of friends and foes in social contexts, and how the methodology of physics can help us understand other fields, etc. I hope you enjoy our discussion. Find me on X at @ProfSchrepel. Also, be sure to subscribe. *** References: ➝ Measuring social dynamics in a massive multiplayer online game (2010) ➝ How women organize social networks different from men (2013) ➝ Multirelational Organization of Large-Scale Social Networks in an Online World (2010) ➝ What is the minimal systemic risk in financial exposure networks? (2020) ➝ Scaling laws and persistence in human brain activity (2003) ➝ New Forms of Collaboration Between the Social and Natural Sciences Could Become Necessary for Understanding Rapid Collective (2024) ➝ Quantifying firm‐level economic systemic risk from nation‐wide supply networks (2022) ➝ Fitting Power-laws in Empirical Data with Estimators that Work for All Exponents (2017) ➝ Complex Systems: Physics Beyond Physics (2017) ➝ Systemic Financial Risk: Agent-based Models to Understand the Leverage Cycle on National Scales and its Consequences (2011) ➝ Peer-review in a world with rational scientists: Toward selection of the average (2010)
Dr. Heather Brown talks about her work in locating and identifying contaminants in the area
Warning: This post discusses statistics about extreme pain that may be distressing. While cluster headaches are a neglected, high-impact issue, understanding their true burden requires appreciating the intensity of suffering involved. The pain often reaches levels far beyond typical human experience, making subjective accounts a valuable datapoint until we have robust methods for quantifying pain intensity. For further context, links to firsthand accounts are provided in the footnote[1]. You no longer have a headache, or pain located at a particular site: you are literally plunged into the pain, like in a swimming pool. There is only one thing that remains of you: your agitated lucidity and the pain that invades everything, takes everything. There is nothing but pain. At that point, you would give everything, including your head, your own life, to make it stop. - Yves, cluster headache patient from France (from Rossi et al., 2018) Key [...] ---Outline:(01:11) Key takeaways(03:57) 1. Introduction(04:00) 1.1. Clinical Features and Pain Comparisons(07:22) 1.2. Treatment and Prevention(10:02) 1.3. The Heavy-Tailed Valence Hypothesis and Existing Metrics(14:49) 1.4. Goal(16:14) 2. Methods(17:43) 2.1 Prevalence(19:17) 2.2 Frequency(22:21) 2.3 Duration(23:53) 2.4 Intensity(25:58) 2.5 Burden Metrics(29:01) 3. Results(29:10) 3.1. Global Burden of Cluster Headache Pain(32:05) 3.2. Reweighting of Extreme Pain(39:41) 3.3. Ceiling Effects(43:34) 4. Recommendations and Conclusions(48:31) AcknowledgementsThe original text contained 26 footnotes which were omitted from this narration. --- First published: November 1st, 2024 Source: https://forum.effectivealtruism.org/posts/geh2g2nKb7Kkp26ze/quantifying-the-global-burden-of-extreme-pain-from-cluster --- Narrated by TYPE III AUDIO. ---Images from the article:Apple Podcasts and Spotify do not show images in the episode description. Try Pocket Casts, or another podcast app.
Elevate your startup's narrative with Chrissy Farr, a renowned health tech journalist and investor. In this Masterclass, members of StartUp Health's Health Moonshot Communities had a chance to interact directly with Farr, Managing Director at Manatt Health, and health tech investor, advisor, and author of Second Opinion. Farr has impressive communications savvy and a deep understanding of the health industry and emerging trends, with an emphasis on the intersection of health and venture capital. She provides a range of go-to-market, fundraising / investor relations, social media strategy, content development and communications counsel to both emerging and established companies as well as the investors behind them. In this insightful episode, you'll learn: The power of storytelling in shaping your company's future How to craft compelling narratives that resonate with investors and the media Leveraging AI tools like ChatGPT for effective communication Balancing founder time between operations and communications Quantifying the impact of your communications efforts The role of social media in your strategy This episode is a must-listen for any health tech founder looking to refine their messaging and build a stronger brand. Tune in now to unlock the secrets of effective storytelling! Do you want to attend Masterclasses live and ask your questions of experts? Members of our Health Moonshot Communities are leading startups with breakthrough technology-driven solutions for the world's biggest health challenges. If you're mission-driven, collaborative, and ready to contribute as much as you gain, you might be the perfect fit. Learn more and apply today. Want more content like this? Sign up for StartUp Health Insider™ to get funding insights, news, and special updates delivered to your inbox.
The US elections are in full flow, with the two big parties focussing on the key swing states that will decide this election. In states like Michigan, a slight movement of voters can determine the outcome. And this means Muslim voters may play a decisive role.To help us understand the political and intellectual climate, I have invited back onto the show Imam Tom Facchine show. Imam Tom has been instrumental in galvanising Muslims behind the anti-Harris campaign, and he joins us from Pennsylvania. You can also support The Thinking Muslim through a one-time donation: https://www.thinkingmuslim.com/DonateSign up to Muhammad Jalal's newsletter: https://jalalayn.substack.comPurchase our Thinking Muslim mug: https://www.thinkingmuslim.com/merch Find us on:Twitter: https://twitter.com/thinking_muslimFacebook: https://www.facebook.com/The-Thinking-Muslim-Podcast-105790781361490Instagram: https://www.instagram.com/thinkingmuslimpodcast/Telegram: https://t.me/thinkingmuslim Host: https://twitter.com/jalalaynWebsite Archive: https://www.thinkingmuslim.comTimestamps0:00 Introduction2:09 - Mehdi re Trump worse8:31 – You are supporting Trump 11:43 – Trump vs Harris 17:47 – Lesser of the two evils 22:33 – Emgage and Harris 29:38 – Emgage no excuse 33:08 – Michigan is the showdown40:46 – Green Party challenges 45:43 – Quantifying our Gaza votes48:05 – Leverage within Democrats 50:55 – Staying at home53:20 – US Exceptionalism 57:16 – Liberal ideology Hosted on Acast. See acast.com/privacy for more information.
Porschia Parker-Griffin, Founder and CEO of Fly High CoachingKey PointsResumes are important but not enough: While resumes provide foundational information, they need to be complemented by strong communication skills and the ability to highlight accomplishments during interviews.The importance of storytelling: Job seekers should focus on telling compelling stories that showcase their achievements and unique qualities.Quantifying accomplishments: Using metrics and numbers can make accomplishments more impactful and memorable.Preparing for interviews: Practice discussing key accomplishments beforehand and use the STAR method (Situation, Task, Action, Result) to structure your responses.Leveraging LinkedIn: Optimize your LinkedIn profile with relevant keywords and skills to increase visibility and attract recruiters. Addressing common concerns: Discuss how to overcome challenges like a lack of a degree or specific personality traits.Success Story: A client who was an executive without an undergraduate degree successfully landed a new job by effectively highlighting their accomplishments and tailoring their approach to interviews.Additional Tips:Customize cover letters: Tailor cover letters to specific job applications.Use performance reviews: Refer to performance reviews for inspiration and data.Practice active listening: Pay attention to the interviewer's questions and tailor your responses accordingly.https://www.fly-highcoaching.com https://www.jobinterviewexperience.com/Master the “Tell Me About Yourself” Question and Stand Out in Any Interview! https://www.jobinterviewexperience.com/tellmeaboutyourself Salary Negotiation - The Headhunters Formular: https://www.jobinterviewexperience.com/salarynegotiation
This might be the most profound conversation I've recorded this year... What if I told you that the puzzle of how to measure and quantify the value of design has already been solved? I know, it sounds too good to be true, right? But hear me out. We all struggle to express the value of design in metrics that businesses understand. The result? We often cut ourselves short because we can't present the impact of our work in a neat spreadsheet. It's frustrating, especially when we see decisions being made that make no sense to us based on "our data". There are many reasons why it's hard to quantify the return on investment of (service) design. We're creating value on a systemic level. We're doing it in co-creation, so attribution is a nightmare. The effects of our work sometimes take a long time to materialize. And the list goes on. So, is all hope lost? Do we throw our hands up in the air? Of course not. Recently, while researching better alternatives to hierarchical goal structures (which are inherently broken), I stumbled upon an article by Stacey Barr. I had never heard of Stacey or her work before. This discovery led me down a massive rabbit hole. Stacey is a leading expert on performance measurement. Over the last 20 years, she has developed and refined a methodology to measure, track, and improve performance that's being used in over 40 countries. The more I read about this methodology, the more I felt that this could be the breakthrough we've been looking for in the design field. I have to be careful not to raise expectations too high, but... Stacey is an unusual guest for the Show. Someone who's completely outside of our design bubble. And that's why this turned out to be such an interesting and eye-opening conversation. In this episode, you'll learn that there is a systemic and reliable approach to figuring out what and how you can measure the impact of design. You can take this approach and apply it to your work today! And best of all, as you'll hear, the approach builds upon a lot of the elements that we as a design community are already familiar with. I hope this episode will show you that we can actually get to measuring the things that matter, not just the things that are easy to measure. And maybe, even maybe, get you a little bit excited about measurement (yes, that's actually possible)! A part that I really liked in our conversation is when we rolled up our sleeves, took an abstract goal like "increasing the sense of belonging," and went step-by-step on how to break this down into more concrete and quantifiable metrics. This exercise really brought things home for me. Keep making a positive impact! ~ Marc --- [ 1. GUIDE ] --- 00:00: Welcome to Episode 212 04:00: Marc's rant on KPIs 05:30: Who is Stacy 08:00: Measuring service design 09:30: Evidence and numbers 13:00: Circle example 16:00: Measuring qualitative aspects 18:00: Quantifying "sense of belonging" 21:00: Circle buddies and belonging 27:00: If you can't experiment... 29:30: Client's vague goals & measurement 34:00: Handling vague ideas & measurement 38:30: Showing value and impact 39:00: Individual vs. team effort 43:00: Qualitative approach 44:00: Significant change method 48:00: Circle community tension 52:00: Measuring systemic impact 58:00: Perfection and systemic impact 1:00:30: Importance of the whole story 1:02:30: Compassion and starting small 1:04:00: Starting small with systemic thinking 1:06:30: Resources for systemic design --- [ 2. LINKS ] --- https://www.linkedin.com/in/staceybarr/ Results Map: https://www.staceybarr.com/measure-up/a-measurable-strategy-on-a-single-page/ Streamlined PuMP approach: https://www.staceybarr.com/measure-up/12-easy-steps-get-started-lean-kpi-methodology/ What is a measure: https://www.staceybarr.com/measure-up/kpis-performance-measures/ --- [ 3. CIRCLE ] --- Join our private community for in-house service design professionals. https://servicedesignshow.com/circle
What did you think of todays show??How can we pass on wealth and keep our kids grounded? Dylan is back for this episode as a new father, so we dive into all things legacy, raising the next generation of entrepreneurs, and how becoming a parent might (or might not) change your approach to real estate investing.In this episode, we also discuss how to measure the value of your business and leverage your assets. You'll learn which asset in your business is the most valuable and how to turn your losses into long-term growth. Tune in now!Topics discussed:Does parenthood impact your investment strategy? (5:22)Raising children without entitlement (8:13)Quantifying intangible assets in business (18:41)The most valuable asset in a real estate business (19:43)When a loss is actually a good investment for your business (23:00)The importance of branding and networking (30:16)Learn more about the Collecting Keys SCALE Community! https://collectingkeys.com/scale/Check out the FREE Collecting Keys “Invest Anywhere” Guide to learn how to find deals in ANY MARKET Completely virtually (this is how we scaled to over a dozen markets)!https://instantinvestor.collectingkeys.com/invest-anywhereFollow us on Instagram!https://www.instagram.com/collectingkeyspodcast/https://www.instagram.com/mike_invests/https://www.instagram.com/investormandan/https://www.instagram.com/dylan_does_dealsThis episode was produced by Podcast Boutique https://www.podcastboutique.com
In today's episode, I'm joined by John Felushko, a product manager at LabStats who impressed me after we recently had a 1x1 call together. John and his team have developed a successful product that helps universities track and optimize their software and hardware usage so schools make smart investments. However, John also shares how culture and value are very tied together—and why their product isn't a fit for every school, and every country. John shares how important customer relationships are , how his team designs great analytics user experiences, how they do user research, and what he learned making high-end winter sports products that's relevant to leading a SAAS analytics product. Combined with John's background in history and the political economy of finance, John paints some very colorful stories about what they're getting right—and how they've course corrected over the years at LabStats. Highlights/ Skip to: (0:46) What is the LabStats product (2:59) Orienting analytics around customer value instead of IT/data (5:51) "Producer of Persistently Profitable Product Process" (11:22) How they make product adjustments based on previous failures (15:55) Why a lack of cultural understanding caused LabStats to fail internationally (18:43) Quantifying value beyond dollars and cents (25:23) How John is able to work so closely with his customers without barriers (30:24) Who makes up the LabStats product research team (35:04) How strong customer relationships help inform the UX design process (38:29) Getting senior management to accept that you can't regularly and accurately predict when you'll be feature-complete and ship (43:51) Where John learned his skills as a successful product manager (47:20) Where you can go to cultivate the non-technical skills to help you become a better SAAS analytics product leader (51:00) What advice would John Felushko have given himself 10 years ago? (56:19) Where you can find more from John Felushko Quotes from Today's Episode “The product process is [essentially] really nothing more than the scientific method applied to business. Every product is an experiment - it has a hypothesis about a problem it solves. At LabStats [we have a process] where we go out and clearly articulate the problem. We clearly identify who the customers are, and who are [people at other colleges] having that problem. Incrementally and as inexpensively as possible, [we] test our solutions against those specific customers. The success rate [of testing solutions by cross-referencing with other customers] has been extremely high.” - John Felushko (6:46) “One of the failures I see in Americans is that we don't realize how much culture matters. Americans have this bias to believe that whatever is valuable in my culture is valuable in other cultures. Value is entirely culturally determined and subjective. Value isn't a number on a spreadsheet. [LabStats positioned our producty] as something that helps you save money and be financially efficient. In French government culture, financial efficiency is not a top priority. Spending government money on things like education is seen as a positive good. The more money you can spend on it, the better. So, the whole message of financial efficiency wasn't going to work in that market.” - John Felushko (16:35) “What I'm really selling with data products is confidence. I'm selling assurance. I'm selling an emotion. Before I was a product manager, I spent about ten years in outdoor retail, selling backpacks and boots. What I learned from that is you're always selling emotion, at every level. If you can articulate the ROI, the real value is that the buyer has confidence they bought the right thing.” - John Felushko (20:29) “[LabStats] has three massive, multi-million dollar horror stories in our past where we [spent] millions of dollars in development work for no results. No ROI. Horror stories are what shape people's values more than anything else. Avoiding negative outcomes is what people avoid more than anything else. [It's important to] tell those stories and perpetuate those [lessons] through the culture of your organization. These are the times we screwed up, and this is what we learned from it—do you want to screw up like that again because we learned not to do that.” - John Felushko (38:45) “There's an old description of a product manager, like, ‘Oh, they come across as the smartest person in the room.' Well, how do you become that person? Expand your view, and expand the amount of information you consume as widely as possible. That's so important to UX design and thinking about what went wrong. Why are some customers super happy and some customers not? What is the difference between those two groups of people? Is it culture? Is it time? Is it mental ability? Is it the size of the screen they're looking at my product on? What variables can I define and rule out, and what data sources do I have to answer all those questions? It's just the normal product manager thing—constant curiosity.” -John Felushko (48:04)
In this episode of The Debrief, we're sitting down with Irwin's VP of Marketing, Melissa Homère, and digging into their team's experience working alongside Focus Lab to level up their existing brand. Irwin had an innovative product and a respected brand, but recognized that they were in need of a refresh to get organized, strategic, and elevated. In our conversation, we touch on everything from:
This one is definitely better watched on Youtube. https://www.youtube.com/thenolecast?sub_confirmation=1 Sorry, DataViz is better there. The Nolecast is the most successful and longest running Florida State podcast. Bud Elliott and Ingram Smith focus mainly on football, but also dabble in baseball and basketball. Please support the show by using our sponsors: The Legendary Home Loans team, Congruity Solutions, and Charlie Park. The show also supported by our Patrons at https://www.Patreon.com/Nolecast https://www.fsuhomeloans.com/ https://congruityhr.com/noles/ https://www.TheBattlesEnd.com/
Eno, Trevor and DVR discuss Matt Chapman's six-year extension with the Giants, a combined no-hitter for the Cubs, who are clinging to slim playoff hopes with three-and-a-half weeks remaining in the regular season. Plus, they discuss baseball's replay system with *10* years now on the ledger and wonder how things might improve in the next 10 years, and they begin a quest to find baseball's most unpredictable (and predictable) pitchers and pitches. Rundown 1:13 Matt Chapman Signs a Six-Year Extension with the Giants 9:04 What's Next for the Giants In Their Push to Return to the Playoffs? 14:55 A Combined No-Hitter From the Cubs 20:26 Baseball's Replay System Turns 10 27:38 We're Ready for the Ball & Strike Call Challenges 34:30 Quantifying a Pitcher's Predictability Related reading 'The Search for the Most Predictable Pitcher' by Kiri Oler of FanGraphs: https://blogs.fangraphs.com/the-search-for-the-most-predictable-pitcher/ 40:52 The Surprising Profile of Josh Hader's Fastball 46:07 The Relationship Between Low Release Points & High iVB 52:13 Trevor Finds the Root Cause of David Bednar's Struggles 59:49 Camilo Doval's Running Cutter and a Rare Instance of 'Weird' Not Being Good Follow Eno on Twitter: @enosarris Follow DVR on Twitter: @DerekVanRiper Follow Trevor on Twitter: @IAmTrevorMay e-mail: ratesandbarrels@gmail.com Subscribe to The Athletic: theathletic.com/ratesandbarrels Hosts: Derek VanRiper & Eno Sarris With: Trevor May Producer: Brian Smith Executive Producer: Derek VanRiper Learn more about your ad choices. Visit megaphone.fm/adchoices
INTRO - This will be quite the passionate finale of Mike, Mike, and Alien. NON-SPOILER REVIEW OF ALIEN: ROMULUS 2:00 - Development Backstory post Fox & Hulu + some creative viral marketing 4:50 - Strong reception numbers & early box office, yet some polarizing tweets & scores 7:37 - Our Theatrical Moviegoing Experience was a Mike, Dan, Mike & Alien Popcorn Bucket. 11:25 - Non Spoiler Script thoughts outlines many pros & cons, potholes, yet no plot holes 16:38 - Praiseworthy performances & characters that differentiate this from other Alien films 22:14 - In Space, No One Can Hear You Set A Scene: some high highs & low lows for the production values and the first of three Mike1 speeches on what makes this franchise great. 30:37 - SPOILER WARNING FOR OUR SPOILER FILLED REVIEW OF ALIEN: ROMULUS 31:24 - The Requiem, or why this film will be remembered has to be the ending, and Mike1 delivers his second big speech on what is otherwise working great in this film. 41:12 - The Most & Least Mike Like Moves pays homage to Dora The Explorer. 45:50 - The Game Over Man (where you knew a fatal error was made) is a segment that showcases Mike's third speech on how we'd never survive a horror movie. 48:06 - Themes we'd rather not dwell on, I mean we could, but we're not gonna: invokes several good discussions on fan service and the tech of the film. 53:14 - Underrated Smart Moves includes praise for some great character work, expansions on the mythology, and a burning question about how they'll handle the sequel, if there is one. 1:00:41 - Least Scary, Scary Moment re: facehuggers, but we have more praise for the writing 1:02:28 - Get Away From Them, You Bitch (or most goosebump inducing moments). 1:05:11 - Nagging Questions We Can't Stop Thinking About 1:10:39 - Quantifying the Goo for Alien: Romulus might just be our masterpiece. 1:19:44 - Final Grades & Our Top Films of the Franchise 1:21:25 - THE OUTRO: includes our socials, your homework, and how to contact us. We also give a requiem for this Mike, Mike, and Alien series and go back through our episode library to recall all of our previous rewatch series. Then we discuss what's coming next from us including upcoming Oscar Race Checkpoints, film festival coverage and film study review episodes.
In this episode, long-time microgreens grower Chris Thoreau and farmer-aggregator Max Becher talk about how they quantify whether or not a crop is successful. Make farming easier with the Paperpot Transplanter and Other Farm Efficiency Tools and Equipment at Modern Grower. Follow PaperpotCo on IG https://instagram.com/paperpotco Podcasts by Diego Footer: Microgreens: https://apple.co/2m1QXmW Vegetable Farming: https://apple.co/2lCuv3m Livestock Farming: https://apple.co/2m75EVG Large Scale Farming: https://apple.co/2kxj39i Small Farm Tools at Modern Grower
Alcohol and its health risks are back in the news and teetotaling is absolutely en vogue (at least here in the States). How much is too much? Are there really NO health benefits? How come one study says booze is good for your heart health and another says it contributes to major cardiac events? Jillian has some answers in this week's Hot Take! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.