Podcasts about poxvirus

TWiV reviews nominees to head NIH, FDA, and CDC, cervical cancer decline following HPV vaccination, local dengue in Texas, human isolate of H5N1 virus is transmissible and virulent in animal models, and shared mechanisms of immune evasion among animal and bacterial viruses. Hosts: Vincent Racaniello, Alan Dove, Rich Condit, Kathy Spindler, Brianne Barker, and Jolene Ramsey Subscribe (free): Apple Podcasts, RSS, email Become a patron of TWiV! Links for this episode Bhattacharya nominated to head NIH (Science) Makary nominated to head FDA (Science) Weldon nominated to head CDC (Chief Healthcare Exec) Cervical cancer declining following vaccination (JAMA Net) Local dengue case in Texas (Texas HHS) H5N1 human isolate transmissible and virulent (Nature) H5 current situation (CDC) Global H5N1 cases (Our World in Data) Conserved immune evasion in animal and bacterial viruses (Cell) Timestamps by Jolene. Thanks! Weekly Picks Brianne – Pale Blue Pod Kathy – PhysicsGirl recent Instagram post, ScienceAdvisor signup free daily sci news distillation, Semi-conducting hydrogels, Bot that can pick up things with a soft touch, “Pigeonbot II”, a drone called LisRaptor, zapping forever chemicals like PFAS with light and here Rich – Vendee Globe Jolene – Center for the Improvement of Mentored Research Experiences Vincent – These two ancient human relatives crossed paths 1.5 million years ago Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

TWiV dissects a study of COVID-19 vaccination which shows that the timing of initial rollout affects disease outcomes more substantially than final coverage or degree of socioeconomic disparity, and discovery of a novel cellular defense comprising a nuclease that is activated by poxvirus infection and cleaves a specific tRNA molecule to inhibit protein synthesis. Hosts: Vincent Racaniello, Rich Condit, Alan Dove, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Research assistant position in Rosenfeld Lab CBER/FDA (pdf) Impact of COVID-19 vaccination trends (Sci Adv) Poxvirus-activated anticodon nuclease (Sci Adv) Letters read on TWiV 1035 Timestamps by Jolene. Thanks! Weekly Picks Brianne – Project Hail Mary Rich – Bird Buddy Alan – Blood, Sweat, and Pixels and Press Reset Vincent – Are microplastics spreading infectious disease? Listener Picks Tom – Henrietta Lacks family settles lawsuit Kathleen – Why Insect Memories May Not Survive Metamorphosis Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

Mpox isn't always a clear and simple diagnosis. Some symptoms may vary, and a long incubation period means it can spread before a person realizes there is infection brewing! But healthcare professionals can learn how to help better suspect and recognize this disease. In addition, clinical stories will be shared to help encourage more interprofessional collaboration and communication amongst healthcare teams to help facilitate better care for patients. ---This is episode 2  of the series: Mpox: A Review of the Poxvirus Previously Known as MonkeypoxSince the outbreak of mpox in 2022, we have learned much about this infectious and communicable poxvirus. Traditionally, many poxviruses were named in relation to animals in which the virus was observed. However, some stigmatizing concepts and language have been attributed to the name monkeypox. So, the name of the virus has been changed from monkeypox to mpox. Join this podcast to learn more about this viral disease now referred to as mpox: presentation, identification, transmission, testing, and overall concepts related to care.Note: This podcast was recorded in December 2022. In the rapidly evolving nature of the topic, bear in mind that some content may not remain current. Please check for updates.Nurses may be able to complete an accredited CE activity featuring content from this podcast and earn CE hours provided from Elite Learning by Colibri Healthcare. For more information, click hereView Episode Show NotesView Episode TranscriptAlready an Elite Member? Login hereLearn more about CE Podcasts from Elite Learning by Colibri HealthcareView this podcast course on Elite Learning Series: Mpox: A Review of the Poxvirus Previously Known as Monkeypox

Join this episode for a review about mpox and what's been learned since the 2022 outbreak. What's behind the name change? Can practically anyone become infected, or is it relatively isolated to a certain group of people? Is it easily spread from one person to another? What can we do? Join now to find out! ---This is episode 1  of the series: Mpox: A Review of the Poxvirus Previously Known as MonkeypoxSince the outbreak of mpox in 2022, we have learned much about this infectious and communicable poxvirus. Traditionally, many poxviruses were named in relation to animals in which the virus was observed. However, some stigmatizing concepts and language have been attributed to the name monkeypox. So, the name of the virus has been changed from monkeypox to mpox. Join this podcast to learn more about this viral disease now referred to as mpox: presentation, identification, transmission, testing, and overall concepts related to care. Note: This podcast was recorded in December 2022. In the rapidly evolving nature of the topic, bear in mind that some content may not remain current. Please check for updates.Nurses may be able to complete an accredited CE activity featuring content from this podcast and earn CE hours provided from Elite Learning by Colibri Healthcare. For more information, click here View Episode Show NotesView Episode Transcript Already an Elite Member? Login hereLearn more about CE Podcasts from Elite Learning by Colibri HealthcareView this podcast course on Elite Learning Series: Mpox: A Review of the Poxvirus Previously Known as Monkeypox

Experts from the FDA and CDC continue their discussion on tecovirimat, or TPOXX, for the treatment of monkeypox in infected individuals. In part two of this mini-series, experts answer physicians' questions about treatment for monkeypox. Guests include Adam Sherwat, MD, Deputy Director, Office of Infectious Disease at FDA's Center for Drug Evaluation and Research; Brett W. Petersen, MD, MPH, Deputy Chief, Poxvirus and Rabies Branch, CDC's Division of High-Consequence Pathogens and Pathology; and Timothy Wilkin, MD, MPH, Professor of Medicine and Assistant Dean for Clinical Research Compliance for Human Research Protections at Weill Cornell Medicine and TPOXX clinical trial lead.

Experts from the AMA, FDA and CDC discuss tecovirimat, or TPOXX, for the treatment of monkeypox in infected individuals. The discussion provides background on tecovirimat, including its current status, availability and access while the drug is under an investigational new drug application. Guests include Adam Sherwat, MD, Deputy Director, Office of Infectious Disease at FDA's Center for Drug Evaluation and Research; Brett W. Petersen, MD, MPH, Deputy Chief, Poxvirus and Rabies Branch, CDC's Division of High-Consequence Pathogens and Pathology; and Timothy Wilkin, MD, MPH, Professor of Medicine and Assistant Dean for Clinical Research Compliance for Human Research Protections at Weill Cornell Medicine and TPOXX clinical trial lead.

In this episode, we discuss the spread of the Pox Virus, the possibility of Biden being able to defeat Trump, Beyoncé, and go over Will Smith's apology video.

En la tertulia profundizamos en la investigación de las vacunas en España. Nos acompañan los virólogos Margarita del Val, directora del Laboratorio de Inmunología Viral del Centro de Biología Molecular Severo Ochoa del CSIC y de la Plataforma de Salud Global; Luis Enjuanes, director del laboratorio de coronavirus del Centro Nacional de Biotecnología (CNB-CSIC); Mariano Esteban, jefe del Grupo de Poxvirus y Vacunas del CNB-CSIC; y Vicente Larraga, responsable del Laboratorio de Parasitología Molecular del Centro de Investigaciones Biológicas Margarita Salas (CIB-CSIC). Escuchar audio

En la tertulia profundizamos en la investigación de las vacunas en España. Nos acompañan los virólogos Margarita del Val, directora del Laboratorio de Inmunología Viral del Centro de Biología Molecular Severo Ochoa del CSIC y de la Plataforma de Salud Global; Luis Enjuanes, director del laboratorio de coronavirus del Centro Nacional de Biotecnología (CNB-CSIC); Mariano Esteban, jefe del Grupo de Poxvirus y Vacunas del CNB-CSIC; y Vicente Larraga, responsable del Laboratorio de Parasitología Molecular del Centro de Investigaciones Biológicas Margarita Salas (CIB-CSIC). Además, nos preocupamos por las dificultades que afrontan los científicos jóvenes con nuestro colaborador y periodista especializado en divulgación científica David Zurdo; el investigador del CSIC Juan García Arriaza; y el presidente de la Federación de Jóvenes Investigadores, David Quinto. Escuchar audio

This episode covers poxvirus!

From the NIH campus (recorded February 2019) Vincent and Rich meet with Bernie Moss to hear about his training and his remarkable 50-year-plus career working on poxviruses. Hosts: Vincent Racaniello and Rich Condit Guest: Bernie Moss Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Link for this episode Reflections on Bernie Moss' career (JBC) Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

From the NIH campus (recorded February 2019) Vincent and Rich meet with Bernie Moss to hear about his training and his remarkable 50-year-plus career working on poxviruses. Hosts: Vincent Racaniello and Rich Condit Guest: Bernie Moss Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Link for this episode Reflections on Bernie Moss' career (JBC) Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

Carles Mesa charla 'Mano a mano' con el cantautor y poeta Luis Ramiro, que nos presenta su nuevo disco, 2029. En el concurso semanal en colaboración con el Instituto Cervantes, resolvemos la pregunta que formulamos la semana pasada y planteamos la siguiente relacionada con la organización que agrupa a los institutos nacionales de cultura de los países de la Unión Europea. A continuación, en ‘El podio’ de Olga Viza, conversamos con Juan García Arriaza, alpinista e investigador del laboratorio de Poxvirus y Vacunas del Centro Nacional de Biotecnología (CNB-CSIC). Escuchar audio

La variole est un fléau... Edward Jenner, un médecin de campagne anglais du XVIIIème siècle, est considéré comme le père de l'immunologie pour avoir trouvé le moyen de combattre cette redoutable maladie virale, il a découvert la vaccination ! Écoutez son histoire dans cet épisode... et abonnez-vous au podcast Culture G !

The TWiVstars reveal the diversity of herpes simplex virus type 2 in a neonatal population, and parallel adaptation of rabbits in three countries to myxoma virus. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Alan Dove, and Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Diversity of HSV2 in neonates (mSphere) Adaptation of rabbits to myxoma virus (Science) Principal component analysis (YouTube) Image credit Letters read on TWiV 540 Timestamps by Jolene. Thanks! Weekly Science Picks Alan- The Quarters Rich- Brian May - New Horizons (Ultima Thule Mix) [Official Music Video] Dickson- How rats became an inescapable part of city living Kathy- Principal Component Analysis (short longer) and Educational Material about Influenza Viruses Vincent - Why “chickenpox parties” are a terrible idea—in case it’s not obvious Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

The TWiVstars reveal the diversity of herpes simplex virus type 2 in a neonatal population, and parallel adaptation of rabbits in three countries to myxoma virus. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, Alan Dove, and Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Diversity of HSV2 in neonates (mSphere) Adaptation of rabbits to myxoma virus (Science) Principal component analysis (YouTube) Image credit Letters read on TWiV 540 Timestamps by Jolene. Thanks! Weekly Science Picks Alan- The Quarters Rich- Brian May - New Horizons (Ultima Thule Mix) [Official Music Video] Dickson- How rats became an inescapable part of city living Kathy- Principal Component Analysis (short longer) and Educational Material about Influenza Viruses Vincent - Why “chickenpox parties” are a terrible idea—in case it’s not obvious Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Learn how to recognise, refer and report Poxvirus infection, with Dr Thomas Blanchard, Consultant in Infectious Diseases, Department of Infectious Diseases and Tropical Medicine, Royal Liverpool Hospital. During a poxvirus outbreak there may be many potential contacts most of whom can be managed by passive surveillance by public health authorities. A symptomatic contact needs to be a risk assessed as most do not need to be seen in full personal protective equipment in a regional infectious diseases unit. For example, a close household contact who develops fever and rash is at high risk, whereas someone who happens to live in the same city and has a fever but no rash is at very low risk. To learn more about Poxvirus, visit BMJ Best Practice. bestpractice.bmj.com/topics/en-gb/1611 _ The purpose of this podcast is to educate and to inform. The content of this podcast does not constitute medical advice and it is not intended to function as a substitute for a healthcare practitioner’s judgement, patient care or treatment. The views expressed by contributors are those of the speakers. BMJ does not endorse any views or recommendations discussed or expressed on this podcast. Listeners should also be aware that professionals in the field may have different opinions. By listening to this podcast, listeners agree not to use its content as the basis for their own medical treatment or for the medical treatment of others.

The TWiVerati discuss the FDA Advisory Committee deliberation on the anti-poxvirus drug tecovirimat, and immune cells in gut-associated lymphoid tissue as the major target during acute murine norovirus infection. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Become a patron of TWiV! Links for this episode ASM Microbe 2018 Support Viruses & Cells Gordon Conference Faculty positions at Icahn School of Medicine FDA meeting materials for tecovirimat(FDA) SIGA Briefing Information (pdf) Errata to the SIGA Briefing Information (pdf) Gut immune cells major targets of norovirus infection(Nat Micro) RNAscope(J Mol Diag) Image credit Letters readon TWiV 493 Weekly Science Picks Alan - Personal Finance for PhDsby Emily Roberts Kathy- Optical illusions fool artificial intelligence Rich- 2017-2018 snowfall graphic Dickson- Dust from the Sahara Vincent - The Last Days of Smallpoxby Mark Pallen Listener Pick Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

From the TWiV team, human cowpox infection possibly acquired from a pet cat, and a new giant mimivirus of green algae with genes encoding enzymes of fermentation. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler Become a patron of TWiV! Links for this episode ASM Microbe 2018 ASV Job Site revamped Support Viruses & Cells Gordon Conference Faculty positions at Icahn School of Medicine Dick Courtney obit Human cowpox infection(NEJM) Mimivirus encodes fermentation genes(Virology) Letters readon TWiV 490 Weekly Science Picks Kathy- Landscapes that look like another world (but they are from Spain) Rich - Brighton Collaboration; Viral Vector Vaccines Safety Working Group (V3SWG)(Chen & DeStefano: Vaccine adverse events: causal or coincidental?) Dickson- Clouds of Jupiter and EBNA2 and autoimmunity Vincent - More than one-third of graduate students report being depressed (original article) Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

The TWiV team reveal the origin of the poxvirus membrane, and how a retrovirus drove the development of the placenta of a lizard. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Become a patron of TWiV! Links for this episode ASV 2018: asv.org, asv2018.umd.edu Support Microbe.tv Origin of poxvirus membrane (PNAS) Poxvirus movies: Movie S1, Movie S2, Movie S3, Movie S4, Movie S5 Lizard placenta from a retrovirus (PNAS) Letters read on TWiV 472 Weekly Science Picks Kathy - Google doodles  Discoverer of photosynthesis  Robert Koch Dickson - Nature Photography Winners Rich - The Raging Idiots Planet Song Alan - Zooborns Vincent - Glass Insects and Plants by Yuki Tsunoda Listener Picks Scott - Sagan Series Paul - SMBC Comics Trudy - If Scientists Wrote Christmas Songs Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Rich Condit joins Nels and Vincent to explain how a vaccinia virus protein customizes ribosomes to favor the translation of viral mRNAs with a stretch of A residues in the 5'-untranslated region. Hosts: Nels Elde and Vincent Racaniello   Become a patron of TWiEVO Rich Condit with Harry Noller (scroll down) Trans-Kingdom mimicry? (Nature) More on RACK1 (Nat Struct Mol Biol) Image credit Letters read on TWiEVO 21 This episode is brought to you by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals free with your first purchase – WITH FREE SHIPPING – by going to blueapron.com/twie. Science Picks Rich - Sniffing out significant “Pee values” Nels - Cuttlefish mimicking a hermit crab (evolutionary context) Vincent - Our first bioRxiv submission! Music on TWiEVO is performed by Trampled by Turtles Send your evolution questions and comments to twievo@microbe.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The Masters of the ScienTWIVic Universe discuss a novel poxvirus isolate from an immunosuppressed patient, H1N1 and the gain-of-function debate, and attenuation of dengue virus by recoding the genome. Links for this episode Paula Pitha-Rowe (Balt Sun) Novel poxvirus (CID) H1N1 and gain-of-function debate (mBio) Recoding dengue virus genome (PNAS) Attenuation by dinucleotide frequency change (PNAS) Codon pair and dinucleotide bias not distinguished (PNAS) Codon pair deoptimization artefact of CG/UA change (eLife) Can engineering subdue viral vaccine reversion? (Virus Evol) Attenuation by a thousand cuts (NEJM) Image credit Letters read on TWiV 351 Weekly Science Picks Alan - Genetic roulette Rich - The Huntington Kathy - Simulated vomiting machine (video) Dickson - Last Cassini Saturn flybyVincent - Decaying Still Life (YouTube) Listener Pick of the Week Ken - Cave meterology (Times, Nature) Send your virology questions and comments to twiv@twiv.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiV team reviews identification of immune biomarkers in CFS/ME patients, and how a cell nuclease controls the innate immune response to vaccinia virus infection. Links for this episode Immune signatures in ME/CFS (Science Adv) 11:15 Systemic exertion intolerance disease (Lancet) 19:50 Cell nuclease controls anti-viral responses (Cell Host Micr) 25:10 Poxvirus decapping enzymes prevent innate responses (Cell Host Micr) 1:15:40 Caps off to poxviruses (Cell Host Micr) Drummer Mohr (YouTube) 1:24:05 Bornavirus in squirrel breeders (ProMedMail) 1:28:45 Principles of Microbial Diversity 5:30 Journal of Microbiology & Biology Education 1:24:25 Cross-stitch by Anne Marie 1:34:40 Letters read on TWiV 329 1:25:00 Timestamps by Jennifer. Thank you! Weekly Science Picks 1:35:10 Alan - NASA Solar Dynamics Observatory videoRich - Mutagenic chain reaction (Video: Genome editing with CRISPR)Kathy - Science Ambassadors ProgramDickson - Street ArtVincent - End Polio Now Listener Pick of the Week Ross - Three PhD Comics on Nature vs Science (one, two, three)Ricardo - Demographic Party Trick Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello and Alan Dove Guests: Dan Barouch and Jeff Teigler This episode of TWiV was recorded before an audience at the Beth Israel Deaconess Medical Center, where Vincent and Alan spoke with Dan and Jeff about AIDS vaccines. Links for this episode: Human study of adenovirus 26 HIV-1 envelope vaccine (J Inf Dis) Seroepidemiology of adenovirus serotypes (Vaccine) SIV infection associated with expansion of gut virome (Cell, TWiV #204) Global approach to HIV-1 vaccine development (Immunol Rev) Innate cytokine responses to adenoviruses (J Virol) microRNAs as mediators of viral evasion (Nat Immunol) Letters read on TWiV 244 Weekly Science Picks Jeff - Science in the News; How to succeed in science (part one and part two)Alan - Nanostructure flowersVincent - Scientific culture Listener Pick of the Week Basel - The sequester blues Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello and Rich Condit Guests: Dave Evans, Stan Lemon, and Lorne Tyrrell Vincent and Rich recorded this episode before an audience at the 2nd Li Ka Shing Institute of Virology Symposium at the University of Alberta, where they spoke with Dave, Stan, and Lorne about their work on poxvirus vaccines and recombination, an enveloped picornavirus, antivirals against hepatitis B and C viruses, and supporting virology research in Alberta. Links for this episode:  Li Ka Shing Institute of Virology Alberta Heritage Foundation for Medical Research Raised on a farm (YouTube) Vaccinia virus strains in Dryvax vaccine (J Virol) Vaccinia DNA polymerase and recombination (J Virol) Picornavirus hijacks cell membrane (Nature) Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello and Kathy Spindler Guests: Nels Elde and Tom Shenk Vincent and Kathy recorded this episode before an audience at the 2013 General Meeting of the American Society for Microbiology in Denver, Colorado, where they spoke with Nels and Tom about their work on the evolution of virus-host conflict and how viruses influence the cell metabolome. Links for this episode:  A cross-species view on viruses (Curr Op Virol) Pox has got a squeeze box (TWiV 198) Saturated fatty acids needed for CMV (PLoS Path) CMV and HSV metabolomes differ (PLoS Path) Video of this episode - view at YouTube Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Rich Condit, Alan Dove, and Kathy Spindler In their final episode of the year, the TWiV team reviews twelve cool virology stories from 2012. Twelve virology stories from 2012: H5N1 (TWiV 190, 182, 177, 173, 168) Polymorphisms that control susceptibility (TWiV 175, 180) New virus receptors (TWiV 166, 210) XMRV: Last nail in the coffin (TWiV special) Polio eradication troubles in Pakistan (NY Times one, two, three; virology blog) Biomedical research crisis (TWiV 208, 184, 189, 194) Polydnaviruses in parasitoid wasps (TWiV 179) Carolyn Coyne’s placental barrier story (TWiV 193) Touring NEIDL (TWiV 200) Epidemiology (TWiV 169, 178) A good year for virus hunting (173, 183, 195, 196, 198, 199, 204) Pox accordion (TWiV 198) Links for this episode: US plans for H5N1 research (ScienceInsider) FDA recommends against Ampligen Rituximab and CFS (PLoS One) No evidence for XMRV in prostate cancer (PLoS One) Retraction of XMRV prostate cancer paper (Retraction Watch) Gender bias among science faculty (PNAS) NEIDL risk assessment Virology 101 at TWiV Letters read on TWiV 213 Weekly Science Picks Rich - Our Mr. Sun (IMDB entry) (wiki)Alan - PubReader from NCBI announcement and instructionsKathy - Popular Mechanics 110 picks for the next 110 yearsVincent - 366 days: Nature's 10 Listener Pick of the Week Matt - The flu vaccine controversy Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Rich Condit, and Mark Challberg Vincent and Rich meet up with Mark Challberg to talk about his scientific career studying viral DNA replication, and his transition to an NIH Program Officer. Subscribe to TWiV (free) in iTunes, at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app. Links for this episode: Purification of vaccinia virus DNA polymerase (J Biol Chem) Adenovirus DNA replication in vitro (PNAS) Herpes simplex viral genes required for DNA synthesis (J Virol) Letters read on TWiV 203 Weekly Science Picks Rich - Mattel Hot Wheels Curiosity RoverVincent - Should H5N1 Moratorium End? Listener Pick of the Week Claudio - DIY lab equipment (Ars Technica) and DIY Bio Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler Vincent, Alan, Rich, and Kathy review fatal avian influenza virus in harbor seals, and poxvirus deployment of genomic accordions to counter antiviral defenses. Links for this episode: Avian influenza virus in harbor seals (mBio) Poxvirus genomic accordions (mBio) Red Queen hypothesis (Wikipedia) TWiV on Facebook Letters read on TWiV 198 Weekly Science Picks Alan - Getting Better: 200 Years of MedicineRich - Khan AcademyKathy - Vi HartVincent - Tweet Keeper Listener Pick of the Week Diane - The Way We Fall by Megan CreweStephen - Amateur Micrography Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Hosts: Vincent Racaniello, Rich Condit, and Kathy Spindler Vincent, Rich, and Kathy discuss Cotia virus, a new poxvirus, Orf virus infections associated with handling goats and lamb, and the innate immune response to prions. Links for this episode: Cotia virus (J Virol) Human Orf virus exposures (MMWR) IRF3 protects agains prion infection (J Virol) A mad cow in America (virology blog) Human orf (pdf) Space shuttle flies outside my window (YouTube) TWiV on Facebook Letters read on TWiV 181 Weekly Science Picks Kathy - Astronomy Picture of the Day (especially this and this)Rich - Tom Lehrer Element Song (YouTube)Vincent - Albert B. Sabin Archives Listener Pick of the Week Mark - Netter's Infectious Diseases by Elaine C. Jong and Dennis L. StevensRichard - Germs, Genes & Civilization by David P. Clark

Vincent, Rich, and Dickson review a meta-analysis on influenza vaccine, a killer virus in fungi that selects against RNAi, and the use of armed and targeted poxviruses for oncolytic virotherapy.

Vincent, Rich, Alan, and Dickson speak with Alfred Sacchetti, MD, Chief of Emergency Services at Our Lady of Lourdes Medical Center, about viral infections encountered in the emergency room.

Vincent, Alan, Dickson and Rich answer listener questions about XMRV, yellow fever vaccine, virus-like particles, West Nile virus, amyotrophic lateral sclerosis and human endogenous retroviruses, multiplicity of infection, and how to make a poxvirus.

Vincent, Dickson, Alan, Rich, and Grant discuss a tanapoxvirus protein that inhibits tumor necrosis factor, purging tumors with myxoma virus, and destruction of the last known stocks of smallpox virus.

Hosts: Vincent Racaniello, Rich Condit, and Ed Niles Vincent, Rich, and Ed discuss the transition from academic scientist to government work, the general program of drug and vaccine development in the biodefense world and at BARDA, and career opportunities for scientists in government. Become a patron of TWiV! Links for this episode: ACAM2000smallpox vaccine Bavarian Nordic's smallpox vaccine Imvamuneand phase II trial Rich and Ed's paper on bacteriophage T7 mRNAs Quandaries of dengue vaccine development Tetravalent dengue vaccine VIVA- virology at Vassar TWiV on Facebook Letters readon TWiV 120 Weekly Science Picks Rich - Dark Sun: The Making of the Hydrogen Bombby Richard Rhodes Ed - Tenth anniversary of the human genome at Science MagazineVincent - Poliovirus fights back Send your virology questions and comments to twiv@microbe.tv.

Vincent, Alan, and Rich review the making of a virulent poxvirus by insertion of the gene encoding IL-4, and severe 2009 H1N1 influenza due to pathogenic immune complexes.

Vincent, Alan, Rich, and Dickson discuss bacteria that can utilize arsenic in place of phosphorus, the passing of Frank Fenner, polio outbreak in The Congo, solving criminal cases of HIV transmission, and classifying viruses by capsid structure.

On episode #84 of the podcast This Week in Virology, Vincent and Rich spoke with Dave Bloom and Grant McFadden about their work on herpesviruses and poxviruses in this episode recorded before an audience at the University of Florida, Gainesville - home of the Gators. Host links Vincent Racaniello, Rich Condit, Dave Bloom, and Grant McFadden Links for this episode: Epigenetic modulation of herpes simplex virus gene expression (thanks, Matthew!) The Red Queen and Tierra virtual environment: article one, two, three (thanks, Jesper!) Hand-held HIV detector (thanks, Jim!) Anti-angiogenic cancer therapy combined with oncolytic virotherapy (thanks, Bill!) TWiV at UF Gainesville (jpg) Letters read on TWiV 84 Weekly science picks: Rich - Charles F. Littlewood photographs Vincent - Not so humble pie (thanks, Sophie!) Grant - The Strangest Man by Graham Farmelo David - Is Parkinson's Disease a prion disorder?

On episode #77 of the podcast This Week in Virology, Vincent, Alan, and Rich revisit circovirus contamination of Rotarix, then discuss poxvirus-like replication of mimivirus in the cell cytoplasm, and whether seasonal influenza immunization increases the risk of infection with the 2009 H1N1 pandemic virus. Host links Vincent Racaniello, Alan Dove, and Rich Condit Links for this episode: Contamination of Rotarix vaccine with porcine circovirus 1 DNA Do you want to know what is in your vaccines? Take the poll Mimivirus replicates in the cell cytoplasm like poxviruses mRNA capping and virus evolution Association between the 2008-09 seasonal influenza vaccine and pandemic H1N1 illness (commentary) Doane paper goes viral Energetics of genome ejection from bacteriophage (thanks Gary!) Five strategies for behavioral adaptation to pathogens and parasites (excerpt; thanks Wladimir!) Letters read on TWiV 77 Weekly science picks: Rich The Way We Work by David Macaulay Alan DimDim Vincent Polio: An American Story by David Oshinsky

On episode #64 of the podcast This Week in Virology, Vincent, Alan, and Rich discuss ten compelling virology stories of 2009. Host links Vincent Racaniello, Alan Dove, and Rich Condit Ten virology stories of 2009: Pandemic influenza: Swine-origin H1N1 virus (TWiV 36) XMRV, prostate cancer, and chronic fatigue syndrome (TWiV 50, 55) AIDS vaccine 'success' (TWiV 51) Colony collapse disorder (TWiV 46, 49) AIDS-like disease in wild chimps (TWiV 45) Diverse viral community in Antarctic lake (TWiV 58) Polyomavirus seroepidemiology in humans (TWiV 26) Poxvirus threatens UK red squirrels (TWiV 63) Polio spreads from Nigeria (TWiV 29) How mosquitoes survive Dengue virus infection (TWiV 21) Picture book on viruses for kids (Thanks Soraia!)

On episode #63 of the podcast This Week in Virology, Vincent, Alan, and Rich talk about US government contract for freeze-dried smallpox vaccine, red squirrels in the UK threatened by poxvirus, and Marseillevirus, another DNA virus from amoebae built for comfort and speed. Host links Vincent Racaniello, Alan Dove, and Rich Condit Links for this episode: US Government awards contract to Bavarian Nordic for freeze-dried smallpox vaccine (pdf and clinical trial) UK red squirrels threatened by poxvirus: news article one and two,epidemiologyand experimental infection Another huge virus from amoebae (Wired article, PNASarticle, review article) Discussion on rabies bait vaccine at virology blog, and status of the program Viral diseases of humans (pdf)

The largest TWiV panel ever assembled takes on XMRV and chronic fatigue syndrome, 2009 chemistry Nobel prizes for ribosome structure, finding new poxvirus vaccine candidates, a brouhaha over leaked Canadian data on flu susceptibility, and transmission of H1N1 influenza to a pet ferret. Hosts: Vincent Racaniello, Dick Despommier, Alan Dove, Jason Rodriguez, and Rich Condit Links for this episode: XMRV and chronic fatigue syndrome XMRV not found in German prostate cancer 2009 Chemistry Nobel Prize for ribosome structure New poxvirus vaccines (e! Science and Virology articles - thanks Jim!) Seasonal flu shots and susceptibility to 2009 H1N1 (one, two, and three) Pet ferret gets H1N1 influenza from owner Weekly Science Picks Dick Nikon photomicroscopy contest winners at SciAm (Dick's article on vertical farming)Alan Make:Rich BBC's Planet Earth (DVD at Amazon)Jason The Collider, the Particle and a Theory About FateVincent An Epidemic of Fear and Misinformants at Wired Magazine

In episode 26 of This Week in Virology, hosts Vincent Racaniello, Alan Dove and guest Rich Condit converse about induction of polyomavirus replication in multiple sclerosis patients treated with the MS drug Tysabri, the extent of human polyomavirus infection, selection of influenza vaccines for the 2009-10 season, cowpox virus transmission from animals to humans, vaccinia-like virus infecting humans and cattle in Brasil, and poxviruses. Links for this episode: JC virus, Tysabri, PML, and mefloquine at virology blog Seroepidemiology of polyomaviruses in human Next season’s influenza virus vaccines and how they are selected Cell-culture propagated smallpox vaccine Cowpox tranmission from rats to humans ( Germany and France) and from cats to humans in Italy Vaccinia-like virus infecting cows and humans in Brasil When good vaccines go wild (review) Mosquito Map (thanks Duncan) Pfeiffer & Kirkegaard paper on quasispecies and virulence in mice Science blog of the week: Coevolvers by Devin Drown Science podcast pick of the week: QuackCast Science book of the week: Listen to the Music: The Life of Hilary Koprowski by Roger Vaughan

In episode 22 of This Week in Virology, host Vincent Racaniello and guest host Chris Upton, a professor in the Department of Biochemistry and Microbiology at the University of Victoria in Vancouver, Canada, converse about hepatitis B in India, AIDS gene therapy with a ribozyme, antibodies that neutralize many influenza virus strains, killing tumors with vaccinia virus, myxoma virus of rabbits, and the Viral Bioinformatics Resource Center. Links in the episode indlude: Hepatitis B outbreak in India AIDS gene therapy clinical trial Antibodies that neutralize many influenza virus strains (papers 1 and 2) Vaccinia virus as an oncolytic agent Mutations that attenuate myxoma virus in rabbits Viral Bioinformatics Resource Center Science blog of the week: The VBRC blog by Chris Upton Science podcast pick of the week: Nova ScienceNow Science book of the week: The Hot Zone by Richard Preston