Podcasts about Enterovirus

Vincent travels to Europic 2024 in Jyväskylä, Finland to speak with Tapani Hovi and Caroline Tapparel about their careers and their research on enteroviruses and elimination of poliomyelitis. Host: Vincent Racaniello Guests: Tapani Hovi and Caroline Tapparel Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Survival of influenza virus on banknotes (Appl Environ Micro) Variant EV-A71 in immunosuppressed patient (Cell Rep) Rhinoviruses and respiratory enteroviruses (Viruses) Isolation of poliovirus in mouse cells producing Pvr (J Clin Micro) Outbreak of paralytic poliomyelitis in Finland (Lancet) Role of environmental poliovirus surveillance in global polio eradication (Epi Infect) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv Content in this podcast should not be construed as medical advice.

Contributor: Ricky Dhaliwal, MD Educational Pearls: Croup Caused by: Parainfluenza, Adenovirus, RSV, Enterovirus (big right now) Age range: 6 months to 3 years Symptoms: Barky cough Inspiratory stridor (Severe = stidor at rest) Use the Westley Croup Score to gauge the severity Treatment: High flow, humidified, cool oxygen Dexamethasone 0.6 mg/kg oral, max 16mg Severe: Racemic Epinephrine 0.5 mL/kg Consider heliox, a mixture of helium and oxygen Very severe: be ready to intubate Bronchiolitis Caused by: RSV, Rhinovirus Symptoms are driven by secretions Symptoms: Cough Wheezing Dehydration (often the symptom that makes them look the worst) Age range: 2 to 6 months Treatment: Suctioning Oxygen IV fluids Nebulized hypertonic saline DuoNebs? No. Asthma Caused by: Environmental factors Viral illness with a predisposition Treatment: Beta agonists Steroids Ipratropium Magnesium (relaxes smooth muscle) References Dalziel SR, Haskell L, O'Brien S, Borland ML, Plint AC, Babl FE, Oakley E. Bronchiolitis. Lancet. 2022 Jul 30;400(10349):392-406. doi: 10.1016/S0140-6736(22)01016-9. Epub 2022 Jul 1. PMID: 35785792. Hoch HE, Houin PR, Stillwell PC. Asthma in Children: A Brief Review for Primary Care Providers. Pediatr Ann. 2019 Mar 1;48(3):e103-e109. doi: 10.3928/19382359-20190219-01. PMID: 30874817. Midulla F, Petrarca L, Frassanito A, Di Mattia G, Zicari AM, Nenna R. Bronchiolitis clinics and medical treatment. Minerva Pediatr. 2018 Dec;70(6):600-611. doi: 10.23736/S0026-4946.18.05334-3. Epub 2018 Oct 18. PMID: 30334624. Smith DK, McDermott AJ, Sullivan JF. Croup: Diagnosis and Management. Am Fam Physician. 2018 May 1;97(9):575-580. PMID: 29763253. Westley CR, Cotton EK, Brooks JG. Nebulized racemic epinephrine by IPPB for the treatment of croup: a double-blind study. Am J Dis Child. 1978 May;132(5):484-7. doi: 10.1001/archpedi.1978.02120300044008. PMID: 347921. https://www.mdcalc.com/calc/677/westley-croup-score Summarized by Jeffrey Olson | Edited by Meg Joyce & Jorge Chalit, OMSII  

*Alzheimer's Linked to Covid-19 and Viral Infections *Paxlovid Doesn't Work Against Long Covid *Novavax Probably the Safest Vaccine according to Dr. McCullough *US Military study on post vaccination myocarditis released *Pfizer Lawsuit on Covid vaccine *Thyroid Diseases Linked to Covid Vaccination studies *Higher Incidence of Covid-19 found among mask wearers *Willow Bark for inactivation of Covid-19 and Enterovirus *1-2 cups of coffee may inhibit Covid-19 infection *New covid variant could be linked to White Lung *All about the new dominant variant JN.1 *Chinese Scientists make inhalable dry powder Covid-19 vaccination *4th vaccination showed negative relation vaccine efficacy against Covid death.

From the European Society for Clinical Virology meeting in Milan, Vincent speaks with Eeva Broberg about her career and her work at the European Centre for Disease Prevention and Control. Hosts: Vincent Racaniello and Heli Harvala Guest: Eeva Broberg Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Global Scholar Travel Awards (ASV) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) European Centre for Disease Prevention and Control Emerging echovirus 30 in Europe (Emerg Inf Dis) RSV surveillance (Eur Resp J) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

Kevin Messacar visits the Incubator to discuss his career as a pediatric infectious disease physician, and his work on enteroviruses that are associated with acute flaccid myelitis and other diseases. Host: Vincent Racaniello Guest: Kevin Messacar Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Global Scholar Travel Awards (ASV) Research assistant position in Rosenfeld Lab CBER/FDA (pdf) Emergence of EV-D68 (Microbio Spectr) 2014 outbreak of EV-D68 (J Med Virol) EV-D68 shedding in households (Emerg Inf Dis) EV-A71 outbreak in Colorado (Lancet Inf Dis) Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

Vincent speaks with Raul and Kostya about the development of novel oral polio vaccine from the Sabin type 2 strain, its deployment in over 600 million children, and whether it can lead to eradication of poliomyelitis. Host: Vincent Racaniello Guests: Raul Andino and Kostya Chumakov Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server MicrobeTV store at Cafepress Research assistant position in Rosenfeld Lab CBER/FDA (pdf) Engineering OPV (Cell Host Microbe) Poliopolis (Lancet) nOPV2 (Polioeradication.org) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

Nicole is the momma of two. A 3 year old son on Earth and her daughter, Cameron, in heaven. An unrecognized virus spread throughout older son's daycare class a week prior to Cameron's birth. She was born via C-section at 35+2 but was not showing signs of sickness. Cameron was admitted to NICU for monitoring. She lived for 29 days and passed from Enterovirus.Nicole and her husband have started "Planting Memories", memorial tree planting, small business, for those people grieving the loss of a loved one by planting a tree in their honor.Nicole is a the definition of badass loss momma, and you can hear in her voice how much she loves her babies. Her spirit, energy and grief vibe I dig very much and I hope you can feel it radiate through wherever you are listening. It's mommas like this that keep me going and I hope she can provide some insight on how to navigate this horrible loss life. Find her on IG https://www.instagram.com/nikuhns614/ Support her small business: https://plantingmemoriesnc.com/  *************************************I am not a doctor or a therapist. I am just a real life loss mom describing her experiences with life after loss. This is my real life, and I'm putting it out there so you feel less alone. For more REAL TALK about baby loss and grief, hit subscribe to be notified when another drops! Instagram https: @thekatherinelazarYoutube: @thekatherinelazarEmail: thekatherinelazar@gmail.comWebsite: www.katherinelazar.com Some helpful resources:https://countthekicks.org/https://www.measuretheplacenta.org/https://www.pushpregnancy.org/https://www.tommys.org/ Local to Atlanta:https://www.northsidepnl.com/ Follow me on Social Media:Instagram and Facebook: @thekatherinelazar

Protecting Kids from Enterovirus 68 (EV-D68) - Dr. John Young, a longtime emergency room physician now specializing in the treatment of chronic and genetic diseases, notes that the children becoming infected have underlying lung or neurological diseases. "They have immune systems that are compromised," he says. "Parents can protect themselves and their kids by maximizing their immune system, and the easiest way to do that is with vitamin D."

A recent unprecedented surge of deadly myocarditis in babies in England and Wales has been linked to enterovirus which is generally mild in infants. Del walks through mechanisms of the COVID-19 vaccines designed specifically to suppress toll-like receptors and why we should be looking into the possibility of this technology inadvertently turning once mild viruses into killers. #Enterovirus #mRNAVaccines #Myocarditis

Hay enterovirus de varios tipos que causan entre 10 y 15 millones de infecciones por años en los EE. UU., por lo general entre fines del verano y principios de otoño.

Nearly three years to the date of Event 201, The Johns Hopkins Center for Health Security, in partnership with World Health Organization and the Bill & Melinda Gates Foundation, conducted Catastrophic Contagion, a pandemic tabletop exercise at the Grand Challenges Annual Meeting in Brussels, Belgium, on October 23, 2022.The exercise simulated a series of WHO emergency health advisory board meetings addressing a fictional pandemic set in the near future. This pandemic was that of an “Enterovirus” originating somewhere near Brazil. It was said this virus has a higher fatality rate than COVID-19 and disproportionally affects children and young people.Here is everything you need to know!Rumble: https://rumble.com/v22pema-catastrophic-contagion-the-jonathan-kogan-show.htmlLocals: https://creatoreconomy.locals.com/supportYouTube: https://www.youtube.com/channel/UCyf3sVAtpgFwRpDXFqJ8bmwTwitter: https://twitter.com/Kogz/status/1607954702901166082?s=20&t=ENND1pE6qTfBOh6PpHik1w ★ Support this podcast on Patreon ★

Nearly three years to the date of Event 201, The Johns Hopkins Center for Health Security, in partnership with World Health Organization and the Bill & Melinda Gates Foundation, conducted Catastrophic Contagion, a pandemic tabletop exercise at the Grand Challenges Annual Meeting in Brussels, Belgium, on October 23, 2022.The exercise simulated a series of WHO emergency health advisory board meetings addressing a fictional pandemic set in the near future. This pandemic was that of an “Enterovirus” originating somewhere near Brazil. It was said this virus has a higher fatality rate than COVID-19 and disproportionally affects children and young people.Here is everything you need to know!Rumble: https://rumble.com/v22pema-catastrophic-contagion-the-jonathan-kogan-show.htmlLocals: https://creatoreconomy.locals.com/supportYouTube: https://www.youtube.com/channel/UCyf3sVAtpgFwRpDXFqJ8bmwTwitter: https://twitter.com/Kogz/status/1607954702901166082?s=20&t=ENND1pE6qTfBOh6PpHik1w ★ Support this podcast on Patreon ★

THE THESIS: Governor DeSantis is the first true leader to go after Big Pharma for the lies, assaults on people's bodies, destruction of people's immune systems and deaths that many in Team Reality believe Pfizer and Moderna caused and continue to cause, with the complete support of The Party. This is THE Wedge Issue between DeSantis and President Trump. How strange is it that Anthony S. Fauci, America's psychopath is now using the same, exact language about the mRNA injections and their fast “approval” as President Trump? THE SCRIPTURE & SCRIPTURAL RESOURCES: I know we are not election Elders or Deacons, I know no man is perfect. My hope is, we will turn to the Word of God to find leaders who most resemble Paul's decision, below. 1 Timothy 3: 1-13Rules for Choosing Leaders and Deacons3 Here is a saying you can trust. If anyone wants to be a leader in the church, they want to do a good work for God and people. 2 A leader must be free from blame. He must be faithful to his wife. In anything he does, he must not go too far. He must control himself. He must be worthy of respect. He must welcome people into his home. He must be able to teach. 3 He must not get drunk. He must not push people around. He must be gentle. He must not be a person who likes to argue. He must not love money. 4 He must manage his own family well. He must make sure that his children obey him. And he must do this in a way that gains him respect. 5 Suppose someone doesn't know how to manage his own family. Then how can he take care of God's church? 6 The leader must not be a new believer. If he is, he might become proud. Then he would be judged just like the devil. 7 The leader must also be respected by those who are outside the church. Then he will not be put to shame. He will not fall into the devil's trap.8 In the same way, deacons must be worthy of respect. They must be honest and true. They must not drink too much wine. They must not try to get money by cheating people. 9 They must hold on to the deep truths of the faith. Even their own minds tell them to do that. 10 First they must be tested. Then let them serve as deacons if there is nothing against them.11 In the same way, the women must be worthy of respect. They must not say things that harm others. In anything they do, they must not go too far. They must be worthy of trust in everything.12 A deacon must be faithful to his wife. He must manage his children and family well. 13 Those who have served well earn the full respect of others. They also become more sure of their faith in Christ Jesus.THE NEWS & COMMENT:We have our DeSantis vs. Trump wedge issue:[AUDIO] - Desantis - "Today I'm announcing a petition with the Supreme Court of Florida to impanel a statewide grand jury to investigate any wrongdoing in Florida with respect to the COVID-19 vaccines."While that divides them, I think both Trump and DeSantis are united in an important way. Unlike the Shiny Shoes like Romney, McConnell and McCarthy, neither President Trump or Governor DeSantis hates the baseWhy Does the GOP Elite Hate Its Own Base?One reason The “GOP” hates the base is that we get in the way of their business model with silly, little things like demands for election integrity [AUDIO] - Kari Lake Attorney Kurt Olsen: "What we found is that there were 300,000 ballots that don't have proper chain of security. What that means is that there's no way to tell where those ballots came from."Don on Substack:“Your podcast reminded me of what a highly respected pastor once said in a sermon: "When truth is lost, falsehood no longer exists." (Robert Johnson, CBCRoseville) How true this is, especially with this administration!.”Trust in “Public” “Health” us gone and cannot come back until people like Fauci are in prison and their supplicants replaced. THIS is the legacy of Fauci, Collins, Redfield, Gates and the CEOs of Moderna and Pfizer. [AUDIO] - AUSTRALIA - Melbourne has started installing defibrillators outside homes, making sure every resident has easy access.. to help with the increase in sudden cardiac arrests. Oh …THIS is their future legacy: another surprise pandemic, this one largely targeting kids. WARNING: Johns Hopkins tabletop exercise "Catastrophic Contagion" October 2022 using enterovirus pandemic simulation (children?); note, they did same thing for 'Event 201' simulating COVID in Oct 2019[AUDIO] - Bill Gates, Johns Hopkins, and the WHO Just Simulated Another Pandemic.They completed a desktop simulation for a new Enterovirus originating near Brazil. The virus has a higher fatality rate than COVID-19 and disproportionately affects children.America's psychopath continues his goodbye tour in his native tongue: lies. [AUDIO] - MSNBC's @morningmika: "Should everybody get boosted" & should I get "my 4th booster"?Dr. Fauci: "Yes, everybody should" get boosted.Anthony Fauci: A Message to the Next Generation of ScientistsDec. 10, 2022Although I hesitate to use the hackneyed expression “It seems like just yesterday,” it ‌does feel that way as I prepare to leave the National Institutes of Health ‌after over five decades. As I look back at my career, I see lessons that may be useful to the next generation of scientists and health workers who will be called on to address the unexpected public health challenges that will inevitably emerge. - Like the one you rehearsed in Event 201? At ‌81, I still can clearly recall the first time I drove onto the bucolic N.I.H. campus in Bethesda, M‌‌d., in June of 1968 as a 27-year-old newly minted physician who had just completed residency training in ‌New York City. My motivation and consuming passion at the time were to become the most highly skilled physician I could‌‌, devoted to delivering the best possible care to ‌my patients. ‌This remains integral to my ‌‌identity, but I did not realize ‌‌how unexpected circumstances would profoundly influence the direction of my career and my life. I would soon learn to expect the unexpected.I share my story, one of love of science and discovery, in hopes of inspiring the next generation to enter health-related careers — and to stay the course, regardless of challenges and surprises that might arise.‌It was during my residency training‌‌ that I became fascinated with the interface between infectious diseases and the relatively nascent but burgeoning field of human immunology. As I cared for many patients with commonplace as well as esoteric infections, ‌‌it became clear ‌‌that ‌‌physicians and other health care providers needed more tools to diagnose, prevent and treat ‌diseases. To merge these ‌‌interests, I ‌accepted ‌a ‌‌fellowship at the National Institute of Allergy and Infectious Diseases ‌‌at the N.I.H. ‌to learn ‌the complex ways cells and other components of the immune system protect us against infectious diseases‌‌. In doing so, I would follow the N.I.H. tradition of bench-to-bedside research by translating‌ laboratory findings into the care of patients and, in turn, taking insights from the clinic back to the laboratory to improve the ‌science.- Wait, so you are back to admitting we have immune systems? Dig deeper into the moment.‌Despite having no prior training in basic science research, ‌I unexpectedly became captivated by the potential ‌‌it had for making discoveries that would benefit not only my patients but also countless other p‌‌eople I might never meet, much less care for as their physician. ‌‌My newfound love for this work posed a major conflict ‌to my well-laid plans for practicing medicine. Ultimately, I chose to follow both paths: to become a research scientist and a physician caring for patients at the N.I.H., where I have been ever since.‌‌There is so much discovery that can happen inside a laboratory and in the clinic — even when you least expect it. Early in my career, I was ‌able to develop highly effective therapies for a group of fatal diseases of blood vessels called ‌vasculitis syndromes. Patients who otherwise would have died ‌‌instead experienced long-term remissions because of the‌‌ treatment protocols I ‌developed. ‌‌My f

Today, in episode 669 our expert Infectious Disease Doctor and Community Health Specialist discuss what you need to know about Public Health. We talk about a new ALS drug that controversially received FDA approval, as well as how Enterovirus may cause a rise in paralysis in children. As always, join us for all the Public Health information you need, explained clearly by our health experts. Website: NoiseFilter - Complex health topics explained simply (noisefiltershow.com) Animations: NoiseFilter - YouTube Instagram: NoiseFilter (@noisefiltershow) • Instagram photos and videos Facebook: NoiseFilter Show | Facebook TikTok: https://www.tiktok.com/@noisefiltershow --- Send in a voice message: https://anchor.fm/noisefilter/message

Protecting Kids from Enterovirus 68 (EV-D68) - Dr. John Young, a longtime emergency room physician now specializing in the treatment of chronic and genetic diseases, notes that the children becoming infected have underlying lung or neurological diseases. "They have immune systems that are compromised," he says. "Parents can protect themselves and their kids by maximizing their immune system, and the easiest way to do that is with vitamin D."For Your Listening Pleasure for these Lockdown / Stay-At-Home COVID and Variants Times - For all the radio shows available on The 'X' Zone Broadcast Network visit - https://www.spreaker.com/user/xzoneradiotv.Our radio shows archives and programming include: A Different Perspective with Kevin Randle; Alien Cosmic Expo Lecture Series; Alien Worlds Radio Show; America's Soul Doctor with Ken Unger; Back in Control Radio Show with Dr. David Hanscom, MD; Connecting with Coincidence with Dr. Bernard Beitman, MD; Dick Tracy; Dimension X; Exploring Tomorrow Radio Show; Flash Gordon; Imagine More Success Radio Show with Syndee Hendricks and Thomas Hydes; Jet Jungle Radio Show; Journey Into Space; Know the Name with Sharon Lynn Wyeth; Lux Radio Theatre - Classic Old Time Radio; Mission Evolution with Gwilda Wiyaka; Paranormal StakeOut with Larry Lawson; Ray Bradbury - Tales Of The Bizarre; Sci Fi Radio Show; Seek Reality with Roberta Grimes; Space Patrol; Stairway to Heaven with Gwilda Wiyaka; The 'X' Zone Radio Show with Rob McConnell; Two Good To Be True with Justina Marsh and Peter Marsh; and many other!That's The ‘X' Zone Broadcast Network Shows and Archives - https://www.spreaker.com/user/xzoneradiotv

References J Virol. 2017 Dec 15; 91(24): e01347-17 Br J Pharmacol. 2014 Apr; 171(8): 1890–1906 European Review for Medical and Pharmacological Sciences 2021; 25: 3762-3771 •Mol Med Rep. 2014 Dec; 10(6): 2811–2818. --- Send in a voice message: https://anchor.fm/dr-daniel-j-guerra/message

This week we will discuss Polio and Enterovirus (EV)-D68 ​Most people who get infected with poliovirus will not have any visible symptoms. About 1 out of 4 people (or 25 out of 100) with poliovirus infection will have flu-like symptoms that can include: Sore throat Fever Tiredness Nausea Headache Stomach pain ​These symptoms usually last 2 to 5 days, then go away on their own. A smaller proportion of people with poliovirus infection will develop other, more serious symptoms that affect the brain and spinal cord: Meningitis (infection of the covering of the spinal cord and/or brain)occurs in about 1–5 out of 100 people with poliovirus infection, depending on virus type Paralysis (can't move parts of the body) or weakness in the arms, legs, or both occurs in about 1 out of 200 people to 1 in 2000 people, depending on virus type ​Paralysis is the most severe symptom associated with poliovirus because it can lead to permanent disability and death. Between 2 and 10 out of 100 people who have paralysis from poliovirus infection die, because the virus affects the muscles that help them breathe. ​Even children who seem to fully recover can develop new muscle pain, weakness, or paralysis as adults, 15 to 40 years later. This is called post-polio syndrome. Note that “poliomyelitis” (or “polio” for short) is defined as the paralytic disease. So only people with the paralytic infection are considered to have the disease. (Credits: CDC) ​Enterovirus was first identified in California in 1962, enterovirus D68 (EV-D68) is one of more than 100 non-polio enteroviruses. EV-D68 can cause mild to severe respiratory illness, or no symptoms at all. Mild symptoms may include runny nose, sneezing, cough, body aches, and muscle aches. Severe symptoms may include wheezing and difficulty breathing. The link between Enterovirus D68 and a polio-like illness has been bolstered by new research showing a spike in both the virus and reports of acute flaccid myelitis in children in 2018, a new government report suggests. The report by the Centers for Disease Control and Prevention reinforces previous research that the virus strikes every other year and in the late summer and early fall. ​Anyone with respiratory illness should contact their doctor if they are having difficulty breathing or if their symptoms are getting worse. Seek immediate medical attention if you or your child develops any of these symptoms following a respiratory illness: arm or leg weakness pain in the neck, back, arms, or legs difficulty swallowing or slurred speech difficulty moving the eyes or drooping eyelids facial droop or weakness  

Amy returns to TWiV to discuss her work on the identification of cross-reactive antibody responses among diverse enteroviruses, and the implications for our understanding of viral pathogenesis and seroprevalence studies. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit Brianne Barker, and Amy Rosenfeld Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ABRCMS ePoster Spring Symposium for Emerging Scientists Cross-reactive enterovirus antibodies (mBio) Poliovirus receptor transgenic mice (virology blog) Timestamps by Jolene. Thanks! Weekly Picks Dickson – European scientists set new record in production of nuclear fusion energy Amy – Alfredo's Magic Wand Brianne – What Happened After the Chicken-Pox Vaccine? Rich – Year Three of COVID-19: Harsh Truths, Realities, and Glimmers of Hope Vincent – Economists Are Fueling the War Against Public Health Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

Amy returns to TWiV to discuss her work on the identification of cross-reactive antibody responses among diverse enteroviruses, and the implications for our understanding of viral pathogenesis and seroprevalence studies. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit Brianne Barker, and Amy Rosenfeld Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ABRCMS ePoster Spring Symposium for Emerging Scientists Cross-reactive enterovirus antibodies (mBio) Poliovirus receptor transgenic mice (virology blog) Timestamps by Jolene. Thanks! Weekly Picks Dickson – European scientists set new record in production of nuclear fusion energy Amy – Alfredo's Magic Wand Brianne – What Happened After the Chicken-Pox Vaccine? Rich – Year Three of COVID-19: Harsh Truths, Realities, and Glimmers of Hope Vincent – Economists Are Fueling the War Against Public Health Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

Cabello, R. R., Feregrino, R. R., & Feregrino, R. R. (2018). Microbiología y parasitología humana: Bases etiológicas de las enfermedades infecciosas y parasitarias. Editorial Médica Panamericana --- Send in a voice message: https://anchor.fm/las-poderosas-celulas-nk/message

Cabello, R. R., Feregrino, R. R., & Feregrino, R. R. (2018). Microbiología y parasitología humana: Bases etiológicas de las enfermedades infecciosas y parasitarias. Editorial Médica Panamericana --- Send in a voice message: https://anchor.fm/las-poderosas-celulas-nk/message

Protecting Kids from Enterovirus 68 (EV-D68) - Dr. John Young, a longtime emergency room physician now specializing in the treatment of chronic and genetic diseases, notes that the children becoming infected have underlying lung or neurological diseases. "They have immune systems that are compromised," he says. "Parents can protect themselves and their kids by maximizing their immune system, and the easiest way to do that is with vitamin D."For Your Listening Pleasure for these Lockdown / Stay-At-Home COVID and Variants Times - For all the radio shows available on The 'X' Zone Broadcast Network visit - https://www.spreaker.com/user/xzoneradiotv.Our radio shows archives and programming include: A Different Perspective with Kevin Randle; Alien Cosmic Expo Lecture Series; Alien Worlds Radio Show; America's Soul Doctor with Ken Unger; Back in Control Radio Show with Dr. David Hanscom, MD; Connecting with Coincidence with Dr. Bernard Beitman, MD; Dick Tracy; Dimension X; Exploring Tomorrow Radio Show; Flash Gordon; Imagine More Success Radio Show with Syndee Hendricks and Thomas Hydes; Jet Jungle Radio Show; Journey Into Space; Know the Name with Sharon Lynn Wyeth; Lux Radio Theatre - Classic Old Time Radio; Mission Evolution with Gwilda Wiyaka; Paranormal StakeOut with Larry Lawson; Ray Bradbury - Tales Of The Bizarre; Sci Fi Radio Show; Seek Reality with Roberta Grimes; Space Patrol; Stairway to Heaven with Gwilda Wiyaka; The 'X' Zone Radio Show with Rob McConnell; Two Good To Be True with Justina Marsh and Peter Marsh; and many other!That's The ‘X' Zone Broadcast Network Shows and Archives - https://www.spreaker.com/user/xzoneradiotv

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.11.06.370916v1?rss=1 Authors: Qin, B., Craven, G. B., Hou, P., Lu, X., Child, E. S., Morgan, R. M. L., Armstrong, A., Mann, D. J., Cui, S. Abstract: RNA viruses are critically dependent upon virally encoded proteases that cleave the viral polyproteins into functional mature proteins. Many of these proteases are structurally conserved with an essential catalytic cysteine and this offers the opportunity to irreversibly inhibit these enzymes with electrophilic small molecules. Here we describe the successful application of quantitative irreversible tethering (qIT) to identify acrylamide fragments that selectively target the active site cysteine of the 3C protease (3Cpro) of Enterovirus 71, the causative agent of hand, foot and mouth disease in humans, altering the substrate binding region. Further, we effectively re-purpose these hits towards the main protease (Mpro) of SARS-CoV-2 which shares the 3C-like fold as well as similar catalytic-triad. We demonstrate that the hit fragments covalently link to the catalytic cysteine of Mpro to inhibit its activity. In addition, we provide the first demonstration that targeting the active site cysteine of Mpro can also have profound allosteric effects, distorting secondary structures required for formation of the active dimeric unit of Mpro. These new data provide novel mechanistic insights into the design of EV71 3Cpro and SARS-CoV-2 Mpro inhibitors and identify acrylamide-tagged pharmacophores for elaboration into more selective agents of therapeutic potential. Copy rights belong to original authors. Visit the link for more info

Biologists Being Basic (B3) hosts Kelsey and Robyn are joined by our friends Megan and Gina as we take a look into the basic biology research behind the headline! This week, we look into a group of related viruses that cause the common cold called enteroviruses, and how these enteroviruses rely on a specific host factor inside human cells to replicate. Further Resources: Kate Shepherd’s article in The Washington Post, “A cure for the common cold? ‘It’s possible,’ scientists say, after new study finds key protein”, covering the Nature Microbiology paper: https://www.washingtonpost.com/nation/2019/09/19/common-cold-cure-protein-stanford-research/ The peer-reviewed research article in Nature Microbiology, “Enterovirus pathogenesis requires the host methyltransferase SETD3” by Diep et al: https://www.nature.com/articles/s41564-019-0551-1 Scientific American also nicely summarizes the peer-reviewed research article: https://www.scientificamerican.com/article/a-newly-identified-protein-may-be-the-key-to-vanquishing-the-common-cold/ ...provides some background information about why a cure for the common cold has been elusive: https://www.scientificamerican.com/article/why-havent-we-cured-the-common-cold-yet/ ...and covers previous outbreaks of the more severe illness of enterovirus infection: https://www.scientificamerican.com/article/poliolike-childhood-muscle-weakening-disease-reappears/ For more info on enteroviruses, including strains that cause more severe disease, visit the CDC: https://www.cdc.gov/non-polio-enterovirus/index.html?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fnon-polio-enterovirus%2Fabout%2Findex.html If you want to watch the ABC news clip we featured in the beginning of the episode about this work: https://abcnews.go.com/GMA/News/video/researchers-discover-cure-common-cold-65660556 We mentioned this paper’s technique to knock out genes using CRISPR, for more info about this trendy gene editing technique check out this Ted-Ed video: https://www.youtube.com/watch?v=6tw_JVz_IEc If you have any questions or comments you can email us at biologistsbeingbasic@gmail.com or find us on twitter or instagram (@biosbeingbasic).

In the first segment, Dr. David Lapides speaks with Dr. Michael Wilson and Dr. Ryan Schubert on their article in Nature Medicine, “Pan-viral serology implicates enteroviruses in acute flaccid myelitis,” which you can read here: https://www.nature.com/articles/s41591-019-0613-1. In the second part of the podcast, Dr. Halley Alexander talks with Dr. Emma Foster about her Neurology paper on her paper discussing that antiepileptic drugs are not independently associated with cognitive dysfunction.  Disclosures can be found at Neurology.org. CME Opportunity: Listen to this week’s Neurology Podcast and earn 0.5 AMA PRA Category 1 CME Credits™ by answering the multiple-choice questions in the online Podcast quiz.

Amy joins the TWiV team to review evidence that enterovirus D68 is an etiologic agent of childhood paralysis, and her finding that the ability of the virus to infect cells of the nervous system is not a recently acquired property. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler Guest: Amy Rosenfeld Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode EV-D68 antibodies in humans before 2014 outbreak (Emerg Inf Dis) Enterovirus antibodies in CSF of AFM patients (mBio) Serology implicates enteroviruses in AFM (Nat Med) EV-D68 neurotropism is not new (mBio) Letters read on TWiV 572 Timestamps by Jolene. Thanks! Weekly Science Picks Amy - Enterovirus biology and pathogenesis and Acute Flaccid Myelitis Association Rich - Tesla Dickson - Nikon Small World 2019 Photo Competition Kathy - Term limits in academic leadership #1 and #2 Vincent - Coywolf: New hybrid carnivore Listener Picks Anonymous - Spill the Beans vaccinated shirts Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Amy joins the TWiV team to review evidence that enterovirus D68 is an etiologic agent of childhood paralysis, and her finding that the ability of the virus to infect cells of the nervous system is not a recently acquired property. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler Guest: Amy Rosenfeld Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode EV-D68 antibodies in humans before 2014 outbreak (Emerg Inf Dis) Enterovirus antibodies in CSF of AFM patients (mBio) Serology implicates enteroviruses in AFM (Nat Med) EV-D68 neurotropism is not new (mBio) Letters read on TWiV 572 Timestamps by Jolene. Thanks! Weekly Science Picks Amy - Enterovirus biology and pathogenesis and Acute Flaccid Myelitis Association Rich - Tesla Dickson - Nikon Small World 2019 Photo Competition Kathy - Term limits in academic leadership #1 and #2 Vincent - Coywolf: New hybrid carnivore Listener Picks Anonymous - Spill the Beans vaccinated shirts Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

 In the second episode from the Karolinska Institute in Stockholm, Vincent speaks with Jan Albert, Petter Brodin, and Anna Smed-Sörensen about their work on enterovirus D68, systems immunology, and human pulmonary viral infection and inflammation. Hosts: Vincent Racaniello Guests: Jan Albert, Petter Brodin, and Anna Smed-Sörensen Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Karolinska Huddinge Evolution of enterovirus D68 (Virus Evol) Maternal anti-viral antibodies in newborns (Nat Med) Respiratory phagocytes in human influenza (Front Immunol) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

 In the second episode from the Karolinska Institute in Stockholm, Vincent speaks with Jan Albert, Petter Brodin, and Anna Smed-Sörensen about their work on enterovirus D68, systems immunology, and human pulmonary viral infection and inflammation. Hosts: Vincent Racaniello Guests: Jan Albert, Petter Brodin, and Anna Smed-Sörensen Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Karolinska Huddinge Evolution of enterovirus D68 (Virus Evol) Maternal anti-viral antibodies in newborns (Nat Med) Respiratory phagocytes in human influenza (Front Immunol) Timestamps by Jolene. Thanks! Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

A look at one of the most common and potentially concerning upper respiratory infections in children. Host: Brian Gilberti, MD https://media.blubrry.com/coreem/content.blubrry.com/coreem/Croup.mp3 Download One Comment Tags: Airway, Infectious Diseases, Pediatrics Show Notes Background Croup is a viral infection starts in the nasal and pharyngeal mucosa but spreads to the larynx and trachea Subglottic narrowing from inflammation Dynamic obstruction Barking cough Inspiratory stridor Causes: Parainfluenza virus (most common) Rhinovirus Enterovirus RSV Rarely: Influenza, Measles Age range: 6 months to 36 months Seasonal component with high prevalence in fall and early winter Differential Bacterial tracheitis Acute epiglottitis Inhaled FB Retropharyngeal abscess Anaphylaxis Presentation & Diagnosis Classically a prodrome of nonspecific symptoms for 1-3 days with low grade fevers, congestion, runny nose. Symptoms reach peak severity on the 4th day “Steeple sign” on Xray (subglottic narrowing) present in only 50% of patients with croup Assess air entry, skin color, level of consciousness, for tachypnea, if there are retractions / nasal flaring (if present at rest or with agitation) & coughing “Westley Croup Score” (https://www.mdcalc.com/westley-croup-score) Chest wall retractions Stridor Cyanosis Level of consciousness Air entry Management

A look at one of the most common and potentially concerning upper respiratory infections in children. Host: Brian Gilberti, MD https://media.blubrry.com/coreem/content.blubrry.com/coreem/Croup.mp3 Download Leave a Comment Tags: Airway, Infectious Diseases, Pediatrics Show Notes Background Croup is a viral infection starts in the nasal and pharyngeal mucosa but spreads to the larynx and trachea Subglottic narrowing from inflammation Dynamic obstruction Barking cough Inspiratory stridor Causes: Parainfluenza virus (most common) Rhinovirus Enterovirus RSV Rarely: Influenza, Measles Age range: 6 months to 36 months Seasonal component with high prevalence in fall and early winter Differential Bacterial tracheitis Acute epiglottitis Inhaled FB Retropharyngeal abscess Anaphylaxis Presentation & Diagnosis Classically a prodrome of nonspecific symptoms for 1-3 days with low grade fevers, congestion, runny nose. Symptoms reach peak severity on the 4th day “Steeple sign” on Xray (subglottic narrowing) present in only 50% of patients with croup Assess air entry, skin color, level of consciousness, for tachypnea, if there are retractions / nasal flaring (if present at rest or with agitation) & coughing “Westley Croup Score” (https://www.mdcalc.com/westley-croup-score) Chest wall retractions Stridor Cyanosis Level of consciousness Air entry Management Mild Croup

The TWiVsters review isolation of a naturally occurring DNA virus from fruit flies, and the cell-type specific function of a small transmembrane protein encoded in an open reading frame upstream of the enterovirus polyprotein. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Kathy Spindler Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Genome-edited babies (Nature) Second CRISPR pregnancy? (MIT Tech Rev) Naturally occurring DNA virus of Drosophila (PLoS Path) Upstream protein coding region in enterovirus genome We missed it in 1988! (J Virol) Letters read on TWiV 522 Timestamps by Jolene. Thanks! Weekly Science Picks Alan - $40 internationally standard cup of tea Rich- Mars InSight Mission Dickson- New York Botanical Garden Train Show Kathy- Comedy wildlife photo awards finalists Vincent - Senator Gillibrand calls for funding AFM research and our Crowdsourcing of EV-D68 research Listener Pick Fernando - Pathfinders by Felipe Fernández-Armesto; Erebus by Michael Palin Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Check out this bonus episode while the Journal of Emergency Medicine Podcast takes a brief spring break.  We searched the last year of JEM Journals for pertinent articles on Infectious Disease topics and put them all together for one focused audio summary.  It is a great review of some previously published excerpts plus new content as well.  Special thanks to my guests on the show, Dr. Lucy Franjic, Dr. Court Crenshaw, and Dr. Aurelia Cheng.

Vincent Racaniello discusses how he ended up studying polio virus and the three eureka moments he’s experienced so far: uncovering the polio genome, discovering the polio receptor, and generating a mouse model of polio disease. Vincent discusses his interest in science communications, including his blog and active podcast network. Host: Julie Wolf Activities of the National Foundation for Infantile Paralysis in the Field of Virus Research (free) on iPhone, Android, RSS, or by email. You can also listen on your mobile device with the Microbeworld app. Julie's biggest takeaways: All three polio virus serotypes are covered by the polio vaccine; type 2 has been eradicated and type 3 is close to being eradicated. Enterovirus 68 is a related enteroviruses that is associated with paralysis, but its receptor and disease progression remain largely unknown. Developing tools and techniques to study one virus that can cross into the central nervous system, such as polio, can set up a lab to study other neurotropic viruses, such as enterovirus 68 and Zika virus. All scientists with access to a computer and a social media account can be effective science communicators! Featured Quotes: "You have to find people to be mentors who you are going to listen to, and if they give you advice, you follow it." (6:57) "It took me one year to sequence the genome of polio, which you could do in five minutes today." (9:52) "We work on infectious agents and a big part of it is to eradicate them and alleviate human disease." (20:32) "On facebook, you’ve lots of friends who are following you; if you show them science, some of them will listen to it." (33:30) "We all have to share what we do. We’re funded mostly by tax dollars, and we have to let the public know what we do." (34:00) Links for this episode Vincent Racaniello Zika Diaries: a blog about the Racaniello lab experiences studying Zika Virus Virology Blog This Week in Virology Scientists: Engage the Public! CHOMA tidbit: Activities of the National Foundation for Infantile Paralysis in the Field of Virus Research by Paul de Kruif Send your stories about our guests and/or your comments (email or recorded audio) to jwolf@asmusa.org.

The TWiV Council explores the finding that facial appearance affects science communication, and evidence that RNA interference confers antiviral immunity in mammalian cells. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, and Kathy Spindler Become a patron of TWiV! Links for this episode JMBE SciComm Issue Facial appearance affects science communication (PNAS) Your face matters to science (virology blog) RNA based antiviral immunity in mammals (Immunity) How mice say nodavirus (TWiV 245) Press release on science meeting gender disparity The Traditional Lecture is Not Dead. I Would Know – I’m A Professor (virology blog) Sound of Silence by Disturbed (YouTube) Letters read on TWiV 449 Weekly Science Picks Kathy - ASV 2017 Virolympics Crossword (pdf) Dickson - The Visible Mouse Alan - Is profitable publishing bad for science? Vincent - Locally Sourced Science Listener Pick Neva - Michael Summers interview and Virus coloring book Intro music is by Ronald Jenkees. Send your virology questions and comments to twiv@microbe.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Guests: Carolyn Coyne and Coyne Drummond Two Coynes join the TWiV overlords to explain their three-dimensional culture model of polarized intestinal cells for studying enterovirus infection.   Links for this episode Carolyn and placentas on TWiV 193 Three-dimensional cell culture model (mSphere) Bioreactor video (JoVE) Neurovirologist Richard T. Johnson, 84 (Hopkins and virology blog) Tardigrade HGT disputed (BioRxiv) Exaptation of archaeal virus capsid protein from Cas4 (Biol Dir) Image credit Letters read on TWiV 367 This episode is sponsored by ASM Microbe Weekly Science Picks Kathy - Tardigrade genome sequence (video)Alan - Antibiotic action nonprofit groupVincent - Ex Machina and genome editing moratoriumRich - Launch photography by Ben CooperKathy - HIV life cycle in video (paper)Dickson - 2015 Nobel Lectures Physiology or MedicineCarolyn - Metapneumovirus entry Listener Picks Tom - Global host-pathogen databaseTrudy - Madame Curie by Eve Curie Send your virology questions and comments to twiv@twiv.tv

A discussion with Dr. Felicia Chow from UC San Francisco Medical Center regarding her review paper on neurologic infectious disease, examining global and patient factors in the changing landscape of infectious disease and the specific neurologic manifestations of viral infections such as Enterovirus, West Nile, and measles virus. Click here to read the full article. 

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiV team discusses the possible association of the respiratory pathogen enterovirus D68 with neurological disease. This episode is sponsored by SciMed Solutions and ASM Education. Links for this episode Clusters of AFP associated with enterovirus D68 (Lancet) 31:35 Novel outbreak enterovirus D68 strain (Lancet Inf Dis) 53:00 Enterovirus D68 in Norway (Euro Surveill) 1:12:00 Unknown enemy (Nature) 1:10:40 Enterovirus D68 on TWiV 302 Letters read on TWiV 331 8:00, 1:23:50 Timestamps by Jennifer. Thank you! Weekly Science Picks 1:53:50 Alan - OU0POLIO ham radio special event station (on air reports)Rich - Crane building itself (YouTube)Kathy - Vaccine heroes LEGO projectDickson - Life at the limitsVincent - Emperor of all Maladies film and Conference gender balance Listener Pick of the Week Jake - Designing useful microbes Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiVocateurs discuss how the RNA polymerase of enteroviruses binds a component of the splicing machinery and inhibits mRNA processing.   Links for this episode Viral polymerase binds Prp8 to inhibit mRNA splicing (PLoS Path) Prp8 protein of the spliceosome (RNA) Nuclear entry of poliovirus RdRp (Virol) RNA processing (TWiV 216) Measles in USA (CDC) Principles of Microbial Diversity Journal of Microbiology & Biology Education Letters read on TWiV 328 Weekly Science Picks Alan - Positively Negative (PLoS One)Rich - ISS assembly (YouTube)Kathy - Ancient treesDickson - Carolyn PorcoVincent - Tony Fauci on Ebola outbreak (YouTube) Listener Pick of the Week David - Shot by ShotJudi - The Power of Herd Immunity Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Host: Brian P. McDonough, MD, FAAFP Dr. Brian McDonough welcomes Tanya Winders, President and Chief Executive Officer for the Allergy and Asthma Network, the leading patient advocacy organization dedicated to ending needless suffering and death due to asthma, allergies, and related conditions. They discuss ways of addressing healthcare access challenges for asthma and allergy patients, from socioeconomic support structures to education models to special risk situations like enterovirus outbreaks.

Enterovirus D68 has received a great deal of recent news coverage – what signs and symptoms should parents look out for? Learn more from a UVA specialist in pediatric infectious diseases. Tagged under: Children's Health

This episode we have Drs. Amy Eapen and Elizabeth Musil as our host doctors. We cover influenza vaccines and pet etiquette. Listen in to learn about enterovirus D68 and what parents should know about it. What is hookah smoking? Find out what it is and why it is harmful. Finally, we answer last month's medical trivia question, which was: "How many cells are in the human body?" Topic Times! Health News - Flu vaccine 1:30 Enterovirus D68 4:40 Parenting Tips- Pet Etiquette 9:30 Hookah Smoking 14:10 Trivia 17:00 This episode was recorded in January of 2014. 

As Ebola fears continue to grow in the United States we'll take a look at how this is working to benefit the Obama administration. Later we'll also talk about the cover-up of weapons of mass detruction found in Iraq as the U.S. was deposing Saddam Hussein . Plus this week's "Outrage of the Week". I'll give you a hint, it has to do with a certain Mayor ignoring freedom of religon.

As Ebola fears continue to grow in the United States we'll take a look at how this is working to benefit the Obama administration. Later we'll also talk about the cover-up of weapons of mass detruction found in Iraq as the U.S. was deposing Saddam Hussein . Plus this week's "Outrage of the Week". I'll give you a hint, it has to do with a certain Mayor ignoring freedom of religon.

EPA seems to have misplaced thousands of text messages; Safety Versus Autonomy; Questions emerge about Ebola readiness; Enterovirus spreading among kids; Iggy Azalea got into it with a paparazzi

Instances of enterovirus D68 are being identified across the country and impacting children at many schools.Tune in to learn what information school nurse should be prepared to share with staff, parents and children. Follow: @schoolnurses @bamradionetwork Julia S. Sammons, MD MSCE is attending physician at the Children's Hospital of Philadelphia (CHOP), where she serves as Hospital Epidemiologist and Medical Director of the Department of Infection Prevention and Control and Assistant Professor in the Division of Infectious Diseases at the Perelman School of Medicine at the University of Pennsylvania.

Join Dr. George as she discusses Ebola, Enterovirus and ObamaCare all happening right now!

TRANSCRIPT EBOLA You know something? The whole scare over Ebola spreading doesn't bother me. I mean, Ebola is deadly, I know. But there has been only one case in the US. That's not enough to get me to wear a full enclosure hazmat suit. I am far more troubled by a President and an Administration that appear content to politicize everything. Even if the politicization puts American lives at risk. The head of the CDCP, Tom Frieden said, "“Even if we tried to close the border, it wouldn’t work. People have a right to return. People transiting through could come in. And it would backfire, because by isolating these countries, it’ll make it harder to help them, it will spread more there and we’d be more likely to be exposed here.” This is utter nonsense. It reflects a point of view based in politics not science. It doesn't even make any sense. If travel to and from Ebola afflicted countries were halted temporarily, how could that possible increase the likelihood that Americans would be exposed to Ebola? It doesn't make the least bit of sense. Border countries in the afflicted areas in Africa have closed their borders to travel to and from there. England and France have closed off travel to and from afflicted countries. And England and France are former imperial countries with stronger ties to those nations than the US. Recently, President Obama encouraged tens of thousands of unaccompanied minors, who were given inadequate medical screenings, to be dispersed throughout the United States and he has refused to inform local and state officials of where and with whom he placed those children. Not accidentally, just weeks after Obama dispersed these children throughout the country, a new disease, Enterovirus D68 is now spreading like a prairie fire across 43 states, primarily affecting children. Some children have died, while others have been permanently disabled with a polio-like paralysis. Experts in epidemiology have noted that viruses like Enterovirus D68 don't just show up in 43 states spontaneously. The only existing plausible explanation of the source of the virus are the children from Central America, where the virus is more common. We already know they were given inadequate medical screenings by professionals who were there. In fact, the Federal agencies, in an effort to keep a lid on the reporting of the medical conditions found in those children, forced doctors and nurses treating them to sign non-disclosure agreements, which, if violated, would result in severe criminal and civil penalties. What the medical staff were expected to overlook, however, so shocked them, some came forward to media outlets anonymously, obviously at great risk to themselves How do the unaccompanied Central American children relate to the Ebola virus response? Well Ladies and Gentlemen, it makes perfect sense. When the children were at the border, if it were made public that many of them were carrying a virus not common in the US, which could easily lead to an outbreak and a serious health risk to American school children, public pressure to seal the southern border would have escalated overnight. Obama's dream of normalizing tens of millions of illegals would have evaporated just as quickly. Then, Ebola happened. An ugly, deadly disease. Not a direct threat on the Southern border, but Obama was looking a step or two ahead. Closing off flights between the US and Ebola afflicted countries would be a first step, quickly followed by demands to......wait for it...........close off the Southern border.  As news of the Enterovirus D68 faded into the background, Ebola took center stage.  But in both cases, the Obama administration response is tailored toward the same end. Politicizing medicine when there is a spreading epidemic of a deadly disease is an immoral act if not a criminal one. What could possibly be the motive? The answer lies in US immigration policy changes threatened by President Obama.  This President is expected to act to normalize millions of illegal aliens with the stroke of his pen. Barack Obama is placing health and safety of school children in America at risk for partisan politics. That may sound incredible. Unbelievable. Incomprehensible. But just look at the facts. They are unforgiving. As Enterovirus D68 spreads into more states and claims more victims, it is being overshadowed by the even greater horror of Ebola. With the death of America's first Ebola patient, the Obama administration announced what they call tougher screening at 5 major international airports where they say 94% of all travel from Ebola afflicted countries enter the US. They plan on asking passengers questions and taking their temperatures as they disembark from the plane. Do you find anything curious about that? I certainly do. First of all, why would we choose to screen less than 100% of flights coming in from West Africa? Does that make any sense with a disease as deadly as Ebola? Second, if a passenger is found to have a fever or other signs of possible infection, what good does it do to screen them as they are deplaning in the US and then again, at only 5 airports? It would mean every single person on the plane is a potential victim, exposed to the virus. The medical professionals say it would require contact with body fluids. Oh! You mean like the kind of body fluids you could be exposed to if you used the restroom after the infected person used it? Or if you sat next to him, or brushed up against him as you moved about the jet in flight? It could also mean that Ebola victims can enter the country through an airport not screening passengers.  These measures are not serious. But if Obama decided to stop flights until the Ebola threat subsided, his capitulation on that would demand he also close that southern border.  No matter where you turn on the issue of Ebola or Enterovirus D68, you inevitably come back to the Southern Border and immigration policy. And what if Ebola happened to hit Central or South America, causing a mass migration to the US without sealing the border? The US should do the common sense thing:  we ought to seal the border and stop all flights to and from Ebola afflicted nations and we should only be flying special charters of medical staff and logistics personnel to and from the hot zone.  President Obama is knowingly and with possible malice, hurting the American people with his policies.  It's hard to understand why he would do this, but the only answer seems to be partisan politics. America deserves a better leader than this. Sources: Politico:  CDC Chief on Ebola CNN:  Parents growing anxious about enterovirus American Thinker:  Invasion of Enterovirus EV-D68 CDC:  Non-polio Enterovirus Journal of Virology: Human Rhinoviruses and enteroviruses in influenza-like Illness in Latin America Sharyl Attkisson:  Polio-like illness claims 5th life in US

MedFlight's Exposure Control Liason, Karen Swecker, joined us on the show to talk about the latest information available on the Ebola virus. We discussed the current recomendations from the CDC on BSI precautions, how to disinfect, and what symptoms you should watch out for.  We also talked about the Enterovirus (EV-D86) and what to watch out for. To wrap up this episode we are bringing you another short pediatric case study from Dr. Ann Dietrich. Please let us know what you think of the show and be sure to include any recommendations for future episodes.  We love to hear from YOU!! Find us at: TuneIn Stitcher medflightradio.com medflightradio@medflight.com

Hosts: Vincent Racaniello, Alan Dove, and Kathy Spindler Vincent, Alan, and Kathy continue their coverage of the Ebola virus outbreak in West Africa, with a discussion of case fatality ratio, reproductive index, a conspiracy theory, and spread of the virus to the United States. This episode of TWiV is brought to you by the Department of Microbiology at Icahn School of Medicine at Mount Sinai. Composed of over 20 virology labs, all centralized in one building in the heart of New York City, this department is a perfect fit for anyone with an interest in pursuing virus research. The Department is presently looking to recruit any prospective graduate students to apply to our program by the December 1st deadline. Interested postdocs are also encouraged to contact faculty of interest. For more information about the Department, please visit www.mssm.edu/MIC. Links for this episode Science communications fellow at ASM Can we get AIDS from mosquito bites? (J La State Med Soc) Why mosquitoes cannot transmit AIDS Isolation of Bundibugyo ebolavirus in Uganda (PLoS Path) Ebola virus disease outbreak, Nigeria (MMWR) Nigeria contains Ebola virus outbreak (NY Times) First Ebola virus case in US (NY Times) Ebola virus disease: USA ex Liberia (ProMedMail) First imported Ebola virus case in US (CDC) Assessing risk of spread of Ebola virus (PLoS Currents) How contagious is Ebola virus? (NPR) Estimating reproductive index of Ebola virus (PLoS Currents) Polio-like illness, EV-D68 suspected (ProMedMail) Polio-like illness, North America (ProMedMail) Four deaths associated with EV-D68 (NY Times) Image credit: Pigott et al eLife Letters read on TWiV 305 Video of this episode - view at YouTube Weekly Science Picks Alan - Under the knife, episode 1Kathy - UCSC Ebola genome portalVincent - Annual Review of Virology, volume 1 Listener Pick of the Week Alan - H5N1Peter - Vomiting LarryDara - I just can't wait for my vaccine! Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Dr. Jean-Marie Maillard explains the Enterovirus & its impact on our state. Candidate Marshall Adame talks about his campaign platform in Election 2014. The Brothaz Unique are busting some moves in Chapel Hill. And Joey Shanks is creating state of the art movie special effects in his home studio.

Dr. Klatte talks about the Enterovirus that is making kids sick across the country.

Dr. Klatte talks about the Enterovirus that is making kids sick across the country.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiVers discuss the growing Ebola virus outbreak in West Africa, and an epidemic of respiratory disease in the US caused by enterovirus D68. Links for this episode Cancer patient saved by measles virus Ebola virus genome sequences (Science) Robert Garry on Ebola outbreak Aerosol transmission WHO Ebola outbreak summary CDC Ebola outbreak page Ebola outbreak epi curve CED Ebola outbreak info graphic Ebola response roadmap (CDC) Ebola outbreak discussion at ICAAC Human trial of Ebola virus vaccine (CNN) Chimpanzee adenovirus vectored Ebola virus vaccine (Nat Med) How US  Ebola patients were cured (Sci Amer) Ebola outbreak could affect 20,000 (NY Times) Ebola infection control resources NLM free access to Ebola papers Science Ebola papers open access Gates donates money for Ebola outbreak (Wash Post) Smuggled bushmeat? (Newsweek) What we are not afraid to say about Ebola (NY Times) Enterovirus D68 outbreak (MMWR) Mark Pallansch on EV-D68 (NPR) Enterovirus D68 (CDC) EV-D68 isolation 1962 (Am J Ep) Outbreak of enterovirus 68 (virology blog) Letters read on TWiV 302 Weekly Science Picks Alan - Index to creationist claimsRich - Wild KrattsKathy - Worn awayDickson - Iceland volcano eruptionVincent - Immune Quest Listener Pick of the Week Kay - Landes Bioscience open access books Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiV team discusses recent cases of polio-like paralysis in California, and the virome of 14th century paleofeces. Links for this episode MERS-CoV in dromedary camels (EID) Virologist Al Kapikian dies Polio-like illness in CA (ProMedMail) Acute flaccid paralysis AFP in India (EID) Enterovirus 68 (MMWR) EV 68 CNS infection (Arch Path Lab Med) Polio-free does not mean paralysis-free (The Hindu) Viruses in 14th century coprolite (AEM) Coprolite and paleofeces Ancient poxvirus (EID) Giant coprolite (WordADay) Letters read on TWiV 274 Weekly Science Picks Alan - The science of science communicationRich - Command and Control by Eric SchlosserDickson - Top 10 plant virusesVincent - Is the Nobel Prize good for science?Kathy - Time to rethink graduate and postdoc education (YouTube) Listener Pick of the Week Jon - Lessons from a Kansas graveyardMike -  Cross a fashion designer with a microbiologist Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv

Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Nissin Moussatche Nissin joins the TWiV crew to discuss an outbreak of lethal disease among Cambodian children, and recombination among attenuated herpesvirus vaccines leading to pathogenic viruses. Subscribe to TWiV (free) in iTunes , at the Zune Marketplace, by the RSS feed, by email, or listen on your mobile device with the Microbeworld app. Links for this episode: Outbreak in Cambodia (CNN) Pathogen mix in Cambodian illness (ProMedMail) Undiagnosed illness in Cambodia (WHO) Enterovirus 71 (virology blog) Recombination among attenuated vaccines (Science) An outbreak of irony (Ed Yong) Infectious laryngotracheitis Gallid herpesvirus 1 (Wikipedia) Iltovirus (ViralZone) TWiV on Facebook Letters read on TWiV 191 Weekly Science Picks Alan - H5N1 genetic changes inventoryRich - Mythbusters: Diet Coke and Mentos (YouTube channel)Nissin - The Pox and the Covenant by Tony Williams, and Tired of War by Tereza BatistaVincent - FAQ: The 'snake bite' portion of your thesis defense Listener Pick of the Week Gopal - All's not fair in science and publishingLuis - The Origin of AIDS by Jacques Pepin (Nature review)Sven - Visualizing information flow in science Send your virology questions and comments (email or mp3 file) to twiv@twiv.tv, or call them in to 908-312-0760. You can also post articles that you would like us to discuss at microbeworld.org and tag them with twiv.

Vincent, Rich, Alan, and Dickson speak with Alfred Sacchetti, MD, Chief of Emergency Services at Our Lady of Lourdes Medical Center, about viral infections encountered in the emergency room.

Vincent, Alan, and Hamish Young discuss bacteriophages in viral vaccines, enteroviruses and diabetes, inhibition of Hendra and Nipah virus replication by the malaria drug chloroquine, and viroids. Links for this episode: Bacteriophages in viral vaccines Presence of enteroviral VP1 protein in pancreatic islets of diabetics Chloroquine inhibits Hendra and Nipah virus replication Review on viroids discovered by TO Diener Mumps in Ireland CDC information on EBV (thanks Megan!) and Journal of Virology paper (thanks Everett!) Science blog of the week: The Weekly Virus Science podcast pick of the week: NIH Research Radio Podcast Science book of the week: Ahead of the Curve: David Baltimore’s Life in Science by Shane Crotty

A Q&A with Dr. John Modlin about Enteroviruses Dr. John Modlin, an international expert in childhood infectious diseases, is the chair the Department of Pediatrics at DHMC and a professor of pediatrics (infectious disease) and of medicine at DMS. He is the former chair of the Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices; has served on many other influential national committees and advisory groups; and has authored more than 150 papers on the development and prevention of human enterovirus infections, poliovirus immunization, public policy on immunizations, and related topics. His studies and advocacy on the potential risks of polio vaccination contributed to a major change in U.S. poliovirus immunization policy in the mid-1990s—to the use of a killed rather than a live vaccine. This is a web extra to an article that appeared in the Summer 2007 issue of Dartmouth Medicine Magazine. To read the article, go to: http://dartmed.dartmouth.edu/summer07/html/vs_virus.php

A Q&A with Dr. John Modlin about Enteroviruses Dr. John Modlin, an international expert in childhood infectious diseases, is the chair the Department of Pediatrics at DHMC and a professor of pediatrics (infectious disease) and of medicine at DMS. He is the former chair of the Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices; has served on many other influential national committees and advisory groups; and has authored more than 150 papers on the development and prevention of human enterovirus infections, poliovirus immunization, public policy on immunizations, and related topics. His studies and advocacy on the potential risks of polio vaccination contributed to a major change in U.S. poliovirus immunization policy in the mid-1990s—to the use of a killed rather than a live vaccine. This is a web extra to an article that appeared in the Summer 2007 issue of Dartmouth Medicine Magazine. To read the article, go to: http://dartmed.dartmouth.edu/summer07/html/vs_virus.php

A Q&A with Dr. John Modlin about Enteroviruses Dr. John Modlin, an international expert in childhood infectious diseases, is the chair the Department of Pediatrics at DHMC and a professor of pediatrics (infectious disease) and of medicine at DMS. He is the former chair of the Centers for Disease Control and Prevention's Advisory Committee on Immunization Practices; has served on many other influential national committees and advisory groups; and has authored more than 150 papers on the development and prevention of human enterovirus infections, poliovirus immunization, public policy on immunizations, and related topics. His studies and advocacy on the potential risks of polio vaccination contributed to a major change in U.S. poliovirus immunization policy in the mid-1990s—to the use of a killed rather than a live vaccine. This is a web extra to an article that appeared in the Summer 2007 issue of Dartmouth Medicine Magazine. To read the article, go to: http://dartmed.dartmouth.edu/summer07/html/vs_virus.php