Podcasts about recombinant dna

Recombinant DNA technologies once confined to the laboratory are now available to just about anyone. Is this a good thing or an extreme risk? David Ishee is self-described biohacker, dog breeder and mad scientist, and merges these passions in cutting edge DIY projects and educational tools. We discuss the opportunities and risks in DIY molecular biology, biohacking and democratization of modern genetic plant, animal and microbial genetic tools.  

During the last several decades Boston has become a biotech Mecca, with its Kendall Square attracting more than 120 biotech companies, both large and small. It is called the most innovative square mile on the planet.  This June BIO will bring over 15,000 biotech leaders to Boston for its 2023 BIO International Convention. Speakers including award-winning journalist and health advocate, Katie Couric, will talk about how they will “Stand up for Science”—the Convention's theme. MassBIO CEO, Kendalle Burlin O'Connell joins host, Rachel King in a wide-ranging discussion about how Boston became the largest biotech hub in the world.

I invited Dr. Tom Maniatis, CEO of New York Genome Center and professor at Columbia University, on the podcast. He is also a cofounder of multiple biotech companies. In this episode, we talked about a lot of interesting topics, like recombinant DNA research controversies, ALS (Amyotrophic Lateral Sclerosis) and one of its most famous patient (Dr. Stephen Hawking), biotech business advice, genomic DNA library, Dr. James Watson (one of the discover of the DNA double helix structure), and more. ---------------------------------- Thanks to the partners: Newsly: https://newsly.mepromo code: EARLYMORNING. Anchor https://anchor.fm Libysn https://libsyn.compromo code: DG Dubby Energy https://www.dubby.ggpromo code for 10% off: DIAMONDGOAT spikeview https://www.spikeview.comhttps://www.instagram.com/spikeview ---------------------------------------------------------------------------------- Listen on: Podcast website: https://anchor.fm/diamondgoat Spotify: https://open.spotify.com/show/0EuhA6WyuerHtVAqcFrFeO Google Podcast: https://www.google.com/podcasts?feed=aHR0cHM6Ly9hbmNob3IuZm0vcy80NzE4MzM5MC9wb2RjYXN0L3Jzcw== RadioPublic: https://radiopublic.com/dg-earlymorning-show-WoML4r Breaker: https://www.breaker.audio/dg-early-morning-show Podcast YT channel clips: https://www.youtube.com/@dgearlymorningshow Reason: https://reason.fm/podcast/dg-earlymorning-show Apple Podcast: https://podcasts.apple.com/us/podcast/dg-early-morning-show/id1575451533 Amazon Music: https://music.amazon.com/podcasts/f050b86c-1dad-4bc3-b12f-6aa5fa62438c Tiktok: @dgearlymorningshow -------------------------------------- Check out my other stuff: Instagram: @itzdiamondgoat Twitter: @lildiamondgoat Main YT channel: youtube.com/diamondgoat Tiktok: @lildiamondgoat Soundcloud: @Lil Diamondgoat Spotify: @Lil Diamondgoat Merch store: https://diamondgoat.creator-spring.com --- Support this podcast: https://podcasters.spotify.com/pod/show/diamondgoat/support

The modern era of genetic engineering has opened tremendous opportunities in medicine and agriculture. But who governs when the technology should be applied? Similar questions were asked in the 1970s at the dawn of recombinant DNA technology. In his new book As Gods - A Moral History of the Genetic Age, Prof. Matthew Cobb discusses these watershed moments in molecular biology, and discusses his views on the newest applications in gene drives, human germline gene editing, and gain-of-function research. Purchase at Amazon

The latest DDW Sitting Down With sponsored podcast features Yuning Chen, Senior R&D Manager at Sino Biological. Recombinant DNA is a field in which Sino Biological has extensive expertise – the company boasts several platforms to use recombinant DNA technology for the manufacturing of a variety of proteins and antibodies to expedite the process of novel drug identification and validation, for example. Chen talks with DDW Publishing Director Lu Rahman about the origins, importance and possible applications of recombinant DNA technology in drug discovery – as well as the opportunities it creates for drug discovery research.

Rishab Jain is a teen innovator, researcher, and content creator. At 13, he was already named America's Top Young Scientist for his novel research in improving radiotherapy for pancreatic cancer patients. In 2018, he was named one of TIME Magazine's 25 Most Influential Teens. In 2022, Rishab won the Regeneron Young Scientist Distinction for his work to improve the efficiency of recombinant DNA technology. Recently at ISEF, he not only won 1st place in Biomedical Engineering but also received the second Regeneron Young Scientist Award of $50,000 for developing an AI-based model to enable rapid and cost-effective production of drugs. He is the founder and President of the Samyak Science Society — a non-profit organization dedicated to promoting STEM education among youth. Rishab is also a YouTuber and online content creator with around 100 k subs on YouTube, creating videos for students to improve their productivity with technology. Available on Youtube and all major podcasting platforms. Like, subscribe and follow the pod if you wanna take a few moments of science with us! You can always tune in to more episodes on www.dropthestem.com ! #stem #stempassion #dropthestem#dropthestemgang #intelisef #intel#science #SSPalumni #artificialintelligence #science #scientific #rsi #regeneron

Recombinant DNA ("gene splicing") was a wildly successful technology in the world of cell biology. Its success gave credibility to the associated "proto-oncogene theory of cancer." The theory piggy-backed on the tool. jUnit was a fairly successful tool in the world of Java programmers. But it was not as successful as recombinant DNA, and it was fairly unsuccessful at promoting its associated theory of test-driven design.This episode looks at what (according to Joan Fujimura's ideas about the history of molecular biology) is required for a tool to be successful, and why jUnit's theory didn't successfully piggyback on the tool.  Sources mentionedCrafting Science: A Sociohistory of the Quest for the Genetics of Cancer, Joan Fujimura, 1997. Molecular Cloning, a Laboratory Manual (Fourth Edition), Michael R. Green and Joseph Sambrook, 2012.“Test Infected: Programmers Love Writing Tests”, Kent Beck and Eric Gamma."JUnit: A Cook's Tour", Kent Beck and Eric Gamma.Junit Recipes: Practical Methods for Programmer Testing, J. B. Rainsberger, 2003.XUnit Test Patterns: Refactoring Test Code, Gerard Meszaros, 2007.My question about the adoption of TDD

On this episode we cover a bit of the biography of vaccines, dovetailing into the current state of vaccination around the globe. My guest on this podcast is Dr. Paul Offit, a world renowned expert and medical pioneer in the field of immunology and virology. He is a professor in the division of Infectious Diseases at the Children's Hospital of Philadelphia and a professor of Vaccinology at the University of Pennsylvania School of Medicine. He is the co-inventor of the rotavirus vaccine recommended for universal use in infants by the CDC, credited with saving hundreds of children's lives every day. Dr. Offit is also currently a member of the FDA's Vaccine Advisory Committee and is a founding advisory board member of the Autism Science Foundation and the Foundation for Vaccine Research. His awards and citations are too numerous to list here (See more of his bio at www.chop.edu/doctors/offit-paul-a) Paul is not only an expert of great renown, he is also very generous and extremely passionate about public health - and it comes through. Vaccination is widely considered one of the greatest medical achievements of modern civilization. Please listen as Paul explains why that is so. We covered a range of topics including: The Ming dynasty, ‘variolation' and smallpox Powdered pustules and other Chinese precursors 18th Century and the founding of vaccinology in the West Jonas Salk and the first successful polio vaccines Rotavirus and the RotaTeq vaccine Recombinant DNA flu vaccines The new mRNA era of vaccines Vaccine risks then and now; we do the math Vaccine controversy and hesitancy throughout history Overview of the current COVID-19 vaccines, Delta and what's next Who should, and should not, get the vaccine FDA timelines, approvals, and licensure For show notes and more, visit www.larryweeks.com 

In this course, recorded in 1998, Dr. Hewlett argues that there is a need for the consideration of purpose and intelligence in Biology. Through a brief history of the sciences, a summary of the basic concepts of Biology, and a concentration on Genetics and the Human Genome Project, he illustrates for the student the wonderful advances of modern science. But while doing so, he emphasizes that however advanced it becomes, Biology will never be able to answer all questions about life and should always be subjected to an overarching philosophy.

Recombinant DNA. The double helix. Mapping the human genome. You know these are all related to our genes, but you might now know how, or what connects them. In this episode of Trailblazers, we answer those questions while exploring the world of genomics. Gain a deeper understanding of our genetic code and how that knowledge is changing how we think about our health with experts like Hallam Stevens, Glenn Cohen, Rick Myers, Eric Green, Amit Khera and Jennifer Doudna. For more on the podcast go to delltechnologies.com/trailblazers

Learn about how curiosity gives your memory a boost; what happened when researchers put feathered hats on birds to see if other birds found them sexy; and how we trick bacteria into making insulin for us. How Curiosity Gives Your Memory A Boost by Cody Gough Gruber, M. J., Gelman, B. D., & Ranganath, C. (2014). States of Curiosity Modulate Hippocampus-Dependent Learning via the Dopaminergic Circuit. Neuron, 84(2), 486–496. https://doi.org/10.1016/j.neuron.2014.08.060 How curiosity changes the brain to enhance learning. (2014, October 2). EurekAlert! https://www.eurekalert.org/pub_releases/2014-10/cp-hcc092514.php  Saville, E. (2014, October 2). Curiosity changes the brain to boost memory and learning. The Conversation. https://theconversation.com/curiosity-changes-the-brain-to-boost-memory-and-learning-32296  Bushak, L. (2014, October 2). How Curiosity Enhances The Brain And Stimulates The Reward System To Improve Learning And Memory. Medical Daily. https://www.medicaldaily.com/how-curiosity-enhances-brain-and-stimulates-reward-system-improve-learning-and-memory-306121  Researchers Once Put Feathered Hats on Birds to See if Other Birds Found Them Sexy by Cameron Duke Basolo, A. L. (1990). Female Preference Predates the Evolution of the Sword in Swordtail Fish. Science, 250(4982), 808–810. https://doi.org/10.1126/science.250.4982.808 Burley, N. T., & Don Ricardo Korski. (1999). “A Taste for the Beautiful”: Latent Aesthetic Mate Preferences for White Crests in Two Species of... ResearchGate; University of Chicago Press. https://www.researchgate.net/publication/23276464_A_Taste_for_the_Beautiful_Latent_Aesthetic_Mate_Preferences_for_White_Crests_in_Two_Species_of_Australian_Grassfinches Picture of birds in hats: https://www.researchgate.net/figure/Artificial-white-crest-worn-by-male-long-tailed-finch-left-and-male-zebra-finch_fig2_23276464  We Trick Bacteria Into Making Insulin For Us by Cameron Duke Gallegos, J. E. (2018, September 14). After a century, insulin is still expensive – could DIYers change that? Medicalxpress.Com; Medical Xpress. https://medicalxpress.com/news/2018-09-century-insulin-expensive-diyers.html  Terry, M. (2018). First Recombinant Insulin Marks 36th Year of DNA Technology | BioSpace. BioSpace. https://www.biospace.com/article/first-recombinant-insulin-marks-36th-year-of-dna-technology/  Gebel, E. (2013). Making Insulin. Diabetes Forecast. http://www.diabetesforecast.org/2013/jul/making-insulin.html Johnson, I. (1983). Human insulin from recombinant DNA technology. Science, 219(4585), 632–637. https://doi.org/10.1126/science.6337396 Recombinant DNA Technology - an overview | ScienceDirect Topics. (2017). Sciencedirect.com. https://www.sciencedirect.com/topics/biochemistry-genetics-and-molecular-biology/recombinant-dna-technology  The History of a Wonderful Thing We Call Insulin | ADA. (2019). Diabetes.org. https://www.diabetes.org/blog/history-wonderful-thing-we-call-insulin Two tons of pig parts: Making insulin in the 1920s. (2013, November). National Museum of American History. https://americanhistory.si.edu/blog/2013/11/two-tons-of-pig-parts-making-insulin-in-the-1920s.html Calculating Insulin Dose  ::  Diabetes Education Online. (2010). UCSF.edu. https://dtc.ucsf.edu/types-of-diabetes/type1/treatment-of-type-1-diabetes/medications-and-therapies/type-1-insulin-therapy/calculating-insulin-dose/  Subscribe to Curiosity Daily to learn something new every day with Cody Gough and Ashley Hamer. You can also listen to our podcast as part of your Alexa Flash Briefing; Amazon smart speakers users, click/tap “enable” here: https://www.amazon.com/Curiosity-com-Curiosity-Daily-from/dp/B07CP17DJY See omnystudio.com/listener for privacy information.

Where I'm coming from (compared to most of my colleagues):Master's in Public Health with a concentration in Health Policy from Yale Medical School.FT Faculty at GWU School of Medicine & Southern Connecticut State University MPH Program, and long-time adjunct faculty at NYMC MPH program in Health Policy.Assistant Commissioner of Health at the NYC Department of Health & Mental Hygiene during the first SARS outbreak.Served as State EMS Director, Consultant to Public Health Canada, Connecticut Department of Public Health, Local Health Departments.(So in other words, I'm not a vaccine expert, but I'm pretty well versed in this stuff) Flu vaccine is bad example, most vaccines are ~80% effectiveOne dose of the MMR vaccine is 93% effective against measles, 78% effective against mumps, and 97% effective against rubella. Two doses of MMR vaccine are 97% effective against measles and 88% effective against mumps. MMR is an attenuated (weakened) live virus vaccine.The Hepatitis B vaccine is 80% to 100% effective in preventing infection or clinical hepatitis in those who receive the complete vaccine series.TDAP vaccines is 80-90% effective after fifth dose, but this decreases to 30-40% after four years. Flu efficacy in the US, by year:200410%200521%200652%200737%200841%200956%201060%201147%201249%201352%201419%201548%201640%201738%201829%201945% est https://en.wikipedia.org/wiki/Influenza_vaccine#:~:text=A%202012%20meta%2Danalysis%20found,24%20months%20(66%20percent).https://www.cdc.gov/vaccines/vpd/mmr/public/index.html#:~:text=One%20dose%20of%20MMR%20vaccine%20is%2093%25%20effective%20against%20measles,(weakened)%20live%20virus%20vaccine.https://www.cdc.gov/vaccines/pubs/pinkbook/hepb.html#:~:text=The%20vaccine%20is%2080%25%20to,receive%20the%20complete%20vaccine%20series.https://www.cdc.gov/pertussis/about/faqs.html#:~:text=CDC%20estimates%20that%20in%20the,4%20years%20after%20getting%20Tdap.Time to Develop Vaccine?Fastest time to develop vaccine: four years https://www.nytimes.com/interactive/2020/04/30/opinion/coronavirus-covid-vaccine.htmlAverage time to develop vaccine: 10 years https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)31252-6/fulltext Historical Vaccine Problems?Cutter Incident (1955): Active polio administered to 200,000, with 200 cases of polio, and 10 deaths. This was a live vaccine, compared to the Pfizer and Moderna COVID vaccines that are Messenger RNA (mRNA) which is just a set of instructions that tells your body to make the protein that resembles part of the Coronavirus...(but not a Recombinant DNA vaccine like I said.)https://www.cdc.gov/vaccinesafety/concerns/concerns-history.htmlhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1383764/https://www.cnbc.com/2020/12/08/pfizer-moderna-covid-vaccine-side-effects-trials.html COVID vaccineDoes it work? Yes, it appears to work pretty well.  But no way is it going to be 95% effective in the real world....What does 95% efficacy mean? Eight out of 18,198 vaccinated with two doses of vaccine got symptoms and a positive COVID test from seven days after their second vaccination through November 14th, 2020. One hundred and sixty-two out of 18,325 vaccinated with placebo got symptoms and a positive COVID test from seven days after their second vaccination through November 14th, 2020.What we don't know: How many of the people in the study were exposed to the COVID virus?If people who got the vaccine can be asymptomatic spreaders?What we do know: You need two shots, and you're going to be sick after your second shot...."The most common solicited adverse reactions were injection site reactions (84.1%), fatigue (62.9%), headache (55.1%), muscle pain (38.3%), chills (31.9%), joint pain (23.6%), fever (14.2%); severe adverse reactions occurred in 0.0% to 4.6% of participants, were more frequent after Dose 2 than after Dose 1, and were generally less frequent in participants ≥55 years of age (≤ 2.8%) as compared to younger participants (≤4.6%).”  https://www.fda.gov/media/144245/download2020 Flu vaccine will probably be even less effective because there was not much flu in Australia to base the vaccine on. But get the flu vaccine anyway this year, because you don't want to get the flu and COVID at the same time....https://www.cdc.gov/flu/season/faq-flu-season-2020-2021.htm#Flu-VaccineEmergency Authorization isn't the same as regular approval....they are going to continue to gather data. https://www.fda.gov/vaccines-blood-biologics/vaccines/emergency-use-authorization-vaccines-explained What's the priority for EMS clinicians?CDC COVID-19 vaccination program interim playbookJurisdictional considerations for Phase 1 subset groups may include, for example:-Phase 1-A: Paid and unpaid persons serving in healthcare settings who have the potential for direct or indirect exposure to patients or infectious materials-Phase 1-B: People who play a key role in keeping essential functions of society running and cannot socially distance in the workplace (e.g., emergency and law enforcement personnel not included in Phase 1-A, food packaging and distribution workers, teachers/school staff, childcare providers), adults with high-risk medical conditions who possess risk factors for severe COVID-19 illness, and people 65 years of age or older (including those living in LTCFs)There may be insufficient COVID-19 vaccine supply initially to vaccinate all those who fall into the Phase 1-A subset, so jurisdictions should plan for additional subsets within that group (see CISA guidance for categories of healthcare personnel).https://www.cdc.gov/vaccines/imz-managers/downloads/COVID-19-Vaccination-Program-Interim_Playbook.pdf CISA guidance on essential critical infrastructure workers (explicitly listed in both categories)Guidance on the Essential Critical Infrastructure Workforce: Ensuring Community and National Resilience in COVID-19 ResponseHealth/Public Health-Healthcare providers including, but not limited to, physicians (MD/DO/DPM); dentists; psychologists; mid- level practitioners; nurses; emergency medical services personnel, assistants and aids; infection control and quality assurance personnel; phlebotomists; pharmacists; physical, respiratory, speech and occupational therapists and assistants; social workers; optometrists; speech pathologists; chiropractors; diagnostic and therapeutic technicians; and radiology technologists.-Workers required for effective clinical, command, infrastructure, support service, administrative, security, and intelligence operations across the direct patient care and full healthcare and public health spectrum. Personnel examples may include, but are not limited, to accounting, administrative, admitting and discharge, engineering, accrediting, certification, licensing, credentialing, epidemiological, source plasma and blood donation, food service, environmental services, housekeeping, medical records, information technology and operational technology, nutritionists, sanitarians, etc.--Emergency medical services workers including clinical interns.--Prehospital workers included but not limited to urgent care workers.Law Enforcement/Public Safety/Other First Responders-Public, private, and voluntary personnel (front-line and management, civilian and sworn) in emergency management, law enforcement, fire and rescue services, emergency medical services (EMS), and security, public and private hazardous material responders, air medical service providers (pilots and supporting technicians), corrections, and search and rescue personnel.   https://www.cisa.gov/publication/guidance-essential-critical-infrastructure-workforce American College of Emergency Physicians supports EMS Clinicians being included in Category 1Ahttps://www.acep.org/corona/COVID-19-alert/covid-19-articles/acep-statement-on-ems-professionals-priority-access-to-the-covid-19-vaccine/ American Paramedic Association and the National EMS Managers Association supports EMS Clinicians receiving a COVID-19 vaccination "as soon as possible."  https://www.nemsma.org/resource/resmgr/covid-19/covid-19_vaccination_conside.pdf EMS included in Category 1A from AIPC and CDC, states may vary. New York: "ICU, EMS, ED top priority" (other first responders were Phase 2)https://www.governor.ny.gov/sites/governor.ny.gov/files/atoms/files/NYS_COVID_Vaccination_Program_Book_10.16.20_FINAL.pdf New Jersey: "Who are "healthcare personnel" in Phase lA? Healthcare personnel are paid and unpaid persons serving in health care settings who have the potential for direct or indirect exposure to patients or infectious materials. This includes any type of worker within a healthcare setting. Examples include, but are not limited to...personnel with variable venues like EMS, paramedics, funeral staff, and autopsy workers."http://nj.gov/health/legal/covid19/12-10-20_PopulationPrioritizationPOD_memo.pdf What should we do:Taking the vaccine is your individual choice based on your own circumstancesEven if you don't want the vaccine, or want to wait, you should support EMS clinicians, both public, non-profit, and private, being in Category 1AEven if vaccine is offered, we still need:Adequate respiratory PPE (half face respirator c P100)Face Shields, Goggles, Gloves, and Gowns Negative pressure ambulancesEquipment and Supplies for CleaningHigh-level decontamination with UV or Hydrogen Peroxide

Ever wonder how to effect real, meaningful change?  Whether it be a social movement or a corporate movement, what does it take to influence positive, important change at scale? Well, you need to create a movement.  In this episode, I speak to International Keynote Speaker and Author Greg Satell on the importance of good information, clear purpose and shared values when creating a successful movement. Greg's Bio: Greg Satell is a popular author, speaker, and trusted adviser bestselling author of Cascades: How to Create a Movement that Drives Transformational Change. His previous effort, Mapping Innovation, was selected as one of the best business books of 2017. Greg regularly contributes to Harvard Business Review and has been featured in other A-list publications such as Barron’s Forbes, Inc. and Fast Company. He is consistently ranked by Innovation Excellence in the top five on its global list of the Top 40 Innovation bloggers and by IDG as one of “10 Digital Transformation Influencers to Follow Today.” You can learn more about Greg on his website, GregSatell.com and follow him on Twitter @DigitalTonto. Also, check out his workshop at https://voltagecontrol.com/virtual-cascades-workshop Greg's TEDx Talk: https://youtu.be/IOt1dLVyHjQ Greg's HBR Articles: https://hbr.org/2019/08/4-tips-for-managing-organizational-change https://hbr.org/2020/03/you-dont-need-a-grand-strategy-to-achieve-organizational-change Resources: Milken institute website, where you can track COVID vaccine and treatment developments.  Several more vaccines have entered testing since my conversation with Greg.  As of May 12th, it's at 125.  https://milkeninstitute.org/covid-19-tracker Srdja Popovich, Serbian political activist.  Here is his 2011 TED talk on How to Topple a Dictator: https://www.ted.com/speakers/srdja_popovic Centre for Applied Nonviolent Action and Strategies (CANVAS): www.canvasopedia.org Asilomar Conference on Recombinant DNA https://www.ncbi.nlm.nih.gov/books/NBK234217/ Partnership on AI: https://www.partnershiponai.org/ Poll finds percentage of people supporting the bombing of the fictional kingdom from the movie Aladin: https://www.publicpolicypolling.com/wp-content/uploads/2017/09/PPP_Release_National_121715.pdf Music by Ryan Sullivan.  Contact: sullybmusic.com

The experimentation of Recombinant DNA is being promoted as a means to insert genetic DNA into the body of a recipient to infuse correct “coding” of immunity molecules into the subject. This is altering human genetics. Unfortunately, the recipient are children of infant age that are required vaccines against Hep B and other diseases that are required by the State in most cases. Is this a normal advancement of science to benefit citizens, or is it a manipulation of the body into some transhumanistic hybrid?

The experimentation of Recombinant DNA is being promoted as a means to insert genetic DNA into the body of a recipient to infuse correct “coding” of immunity molecules into the subject. This is altering human genetics. Unfortunately, the recipient are children of infant age that are required vaccines against Hep B and other diseases that are required by the State in most cases. Is this a normal advancement of science to benefit citizens, or is it a manipulation of the body into some transhumanistic hybrid?

If you are still a high school or college student and you want to get into this industry, I hope this podcast will open up the pandora’s box of opportunities we’ll be laying out before you. But even if you are maybe a bit further along in your career, there is always time to jump in. Marie Gibbons is probably the most famous clean meat scientist for multiple reasons. She is funded by the Good Food Insitute, she is currently doing her research in Harvard, and she’s really passionate in what she does. Marie’s passion and kindness resonate in this interview. She is an extremely authentic and transparent scientist who explains the process of clean meat in simple yet dense detail. Do note, some of the experiences Marie has being a farm animal veterinarian are quite graphic, of course, to prove a point. We only talk about it in the beginning, but just be forewarned. Otherwise, I’m glad that Marie has a sense of humor so enjoy a bunch of smart alec scientists talk about clean meat among other things. Sponsor - BAKERpedia This episode is brought to you by BAKERpedia – your one-stop, resource that answers all your questions on industry trends, ingredient information, food safety and more. It’s shared knowledge, freely available, always. BAKERpedia.com – we do all the thinking so you can focus on your business. Sponsor – FoodGrads If you are even just a little bit interested in a career in food & beverage, you should join FoodGrads.  It’s an interactive platform where you can hear about different careers, hear from your peers, have a voice and share your story as well as ask specific questions and get feedback from industry experts across the sector. Nicole is offering free job postings in the next two months and I highly suggest taking this offer. Email nicole@foodgrads.com and she'll give you instructions. Join FoodGrads today! Just go to Foodgrads.com Sponsor – ICON Foods Unless you have been living under a rock you can not get away from Halo Top Ice Cream’s amazing success with their under 300 calories per pint ice cream. What’s a frozen dessert manufacturer to do to compete? Pick up the phone and call Icon Foods at 310-455-9876 or find them on the web at www.iconfoods.com that’s what. They have a new HiPro Ice Cream Dry Mix that delivers amazing mouthfeel and sumptuous flavor all under 300 calories per pint. But, here’s the best part; you simply add the HiPro dry mix to any milk type, add glycerin and inclusions and you are off to the races with an amazing finished product lickity split. Icon Foods HiPro Ice Cream Dry Mix comes in hard ice cream mix, soft serve, vegan and wait for it… Keto. Call my friends at Icon and let them ReformulateU. 310-455-9876. Show Notes On the shownotes, I did something special and labeled Opportunities that are available in the industry. Clean Meat by Paul Shapiro 80,000 hours podcast – effective altruism podcast Zak Weston Harvard medical school Gym Meats When someone asks what you do for a living, what do you usually tell someone in a sentence or less?: I grow animal cells for meat. Dr. George Church How did you get to work with Dr. George Church?: I met him at an Effective Altruism conference and I contacted him after the show. We got to talking and here I am! How do you get funding for Clean Meat?: You have to write a grant or a giant lab report. When did you find interest in Clean Meat?: It came from when I was 12 years old and my dad gave me two pet snakes. I had to feed them mice. In order for snakes to live, they have to kill and then I thought of clean meat. Then I became a veterinarian and became a farm animal vet. And I realized farm animals aren’t treated the same way as other animals. I had to do a lot of really gruesome stuff as a farm animal veterinarian. If they get a disease, we have to find painful ways to remove it. How do you get in the foot in the door for Clean Meat?: Just like the food industry, there are so many avenues to help with clean meat. How is clean meat made? Opportunity: If you want to get into the science, focus on 3D modeling to prepare for baby back ribs and t bone steak. I can grow a nugget for $400 dollars Opportunity: Replace Fetal Bovine Serum to make plant-based growth media Opportunity: Somatic Cell Technology:Use pluripotency and turn them back into Stem Cells. Media components: Gatorade and Protein Powder. The standard Protein Powder has Fetal Bovine Serum Fetal Bovine Serum is quite a painful process by stabbing unborn baby cows in the heart to extract the fluid The growth factors have to be part of the serum which is the hard part because they have to tell the cell to grow. Opportunity: You can create growth factors with Recombinant DNA technology. You can get bacteria to create growth factor Algae Soylent Green Opportunity: Cut out the middle man to get the cells to automatically grow their own growth factor How do you change cells?: DNA, RNA, gene editing, environmental media etc. Induced Plurry Potent Opportunity: Scaling up Clean Meat. Regulatory, what is it going to be called? Opportunity: Induced Immortalization. To get cells to continuously grow until we said no. We just need to tell them to grown certain cells. Embryonic Stem Cells should be immortal. Telomerase Telomeres – serve as a buffer for our chromosomes to create DNA. What kind of resources do you use to find out about Clean Meat?: Sometimes, it’s literature based, sometimes it’s the feedback from professors and industry folks. Opportunity: Though there isn’t a lot of clean meat research, there is a ton of research in regenerative agriculture. Pigs are so physiologically similar to humans, which is why there is tons of research on pigs. We still need a lot of hands to sift through the research My Food Job Rocks: I get to study how life works. And not only that, but I have a chance to help animals and end animal suffering What would be your dream job title?: Clean Meat Scientist. I am funded by the Good Food Institute Harvard is generally interested in clean meat. Clean Meat and Plant-based meat actually has a lot of overlap. What companies are doing a great job in Clean Meat? Memphis Meats Mosa Meats JUST Foods Finless Foods What’s your favorite quote book or kitchen item: Blender and George Foreman Grill. I can make BLAT. Vegan bacon. If you’re trying to go more plant-based, you need to start with products with a lot of things going on and eliminate meat. A vegan food you really like: Tofu Scramble with Salad Greens and Asian spices Kimchi and lactic acid Smoothies – vegan chocolate protein powder, blueberries, greens Soylent Drinks Necter Soylent Rice and beans, and Indian food Do you have any advice to be a clean meat scientist?: Get familiar with cellular biology. All of these companies are looking for people and if you want to get into this, reach out and apply. It doesn’t hurt to reach out. If you want to reach out, you can go to the GFI and contact them. What should colleges teach you about to prepare you for life?: Taxes haha. Business course. There is a lot of common sense in business. A mandatory class on how to grow food. Where can we find you for advice?: My email is on the Harvard website, also on facebook, linkedin, or Instagram. I’m kind of bad for getting on emails but be patient.  

Neuroscience research needs help from many fields, including engineering. Dr. Talia Lerner describes some of the engineering tools that she uses to study neural circuits in animal models, especially involving dopamine. She is a professor and basic science researcher at Northwestern University in Chicago, and she studies these circuits in the hopes of improving mental health diagnoses and treatments. Dr. Lerner also shares her thoughts on what doctors, scientists, and engineers will tackle in future neuroscience work. Related to this episode: • Dr. Talia Lerner's lab, The Lerner Lab: http://lernerlab.org/ • Videos of neurons visualized with new techniques: http://lernerlab.org/research/ • Article on some common genetic links among depression, schizophrenia, autism, and other conditions: http://bigthink.com/21st-century-spirituality/researchers-just-discovered-a-genetic-link-between-alcoholism-autism-bipolar-disorder-depression-and-schizophrenia • Neurotransmitters (such as glutamate), on Wikipedia: https://en.wikipedia.org/wiki/Neurotransmitter • Neuromodulators (such as serotonin, dopamine), on Wikipedia: https://en.wikipedia.org/wiki/Neuromodulation • Synapses (or neuronal connections), on Wikipedia: https://en.wikipedia.org/wiki/Synapse • Action potentials (or neuronal signals), on Wikipedia: https://en.wikipedia.org/wiki/Action_potential • Karl Deisseroth's Lab at Stanford: https://web.stanford.edu/group/dlab/ • Optogenetics resources: https://web.stanford.edu/group/dlab/optogenetics/index.html • GFP (green fluorescent protein), at Connecticut College: https://www.conncoll.edu/ccacad/zimmer/GFP-ww/GFP-1.htm • Recombinant DNA, at Khan Academy: https://www.khanacademy.org/science/biology/biotech-dna-technology/dna-cloning-tutorial/v/dna-cloning-and-recombinant-dna • CLARITY resources: http://clarityresourcecenter.org/ • Article on the history of hydrogels: http://www.jbiomeds.com/biomedical-sciences/history-and-applications-of-hydrogels.php?aid=7218 • NeuWrite West (formerly Stanford Neuroblog): http://www.neuwritewest.org/ • Berkeley Science Review (science news): http://berkeleysciencereview.com/ • Carry the One Radio (podcast): http://www.carrytheoneradio.com/ • Viral neuronal tracing, on Wikipedia: https://en.wikipedia.org/wiki/Viral_neuronal_tracing • Article on using the engineered rabies virus against brain cancer: http://www.sciencemag.org/news/2017/02/how-stop-brain-cancer-rabies • Ed Callaway, neuroscientist: http://callaway.salk.edu/ • Ian Wickersham, neuroscientist: http://wickershamlab.org/ian-wickersham/ • Biosafety levels, from the Centers for Disease Control and Prevention: https://www.cdc.gov/training/QuickLearns/biosafety/ Our closing music is “Late for School” by Bleeptor, used under a Creative Commons Attribution License: https://creativecommons.org/licenses/by/4.0/ Subscribe and find more podcast information at: http://www.k12engineering.net. Support Pios Labs with regular donations on Patreon: https://www.patreon.com/pioslabs, or send one-time contributions by buying us coffee: https://ko-fi.com/pioslabs. Thanks to our donors and listeners for making the show possible. The K12 Engineering Education Podcast is a production of Pios Labs: http://www.pioslabs.com.

Interview with Genetic Genealogist TL Dixon about his journey to find his biological parents, discovering his African DNA cousins and his advice for learning more about your Native American and African roots. Interview by Anthony May (amay@nketa.org) brought to you by www.nketa.org. How To Contact TL Dixon: Blog: "Roots and Recombinant DNA" (http://www.rootsandrecombinantdna.com) Email: KingGenomebyTLDixon@gmail.com Facebook Groups: African Diaspora Ancestry Explorer Cypher (https://www.facebook.com/groups/1270364649776861/) Africana Genetic Genealogy Consortium (https://www.facebook.com/groups/201329460443626/)

We welcome Mark Schmidt back to the show this week, and Ray Dillon makes his first appearance on yet another great installment of Canned Air! First, in this week’s Retro Roundtable, titled "Fantastic Places and Where to Find Them”, we take turns sharing what fictional place we would most like to visit. With so many stretching across pop culture, it’s hard to pick just one. Narnia? The Mushroom Kingdom? Latveria…? Come in and see if we name your favorite fictional place. Then we turn our full attention to Mark and Ray to discuss The Threat, relaunching on Kickstarter very soon. In the not too distant future, humanity is dying at apocalyptic rates. The only solution is through Recombinant DNA, which causes mutations in a small percentage of the population. These people become know as VIRALS. As cybernetically enhanced humans patrol the streets of Houston, preserving a hellish segregation, those who work for ANITEC are protected in their lives of luxury, while the rest are left to scrape together what life they can in the dangerous under-streets of the city. But there are still some, who will rise to seize a better future, becoming a THREAT to those who would keep them down. Keep an eye out for this Kickstarter for your chance to support The Threat! StratumComics.com @StratumComics @TheThreatComic RayDillon.com @RayDillon @GateskeeperComic Cinebook.co.uk @CinebookLtd ‘Eye of the Storm' Written and Performed by In Urgency InUrgencyOfficial.com @InUrgencyCA ShroudMediaLLC.com @ShroudMedia CannedAirPodcast.com @CannedAirPod @Canned_Air Society6.com/CannedAirPod

We start this week by paying tribute to the man behind the cowl, Adam West. Adam introduced Batman to a new generation of fans in the 60’s and put his own heart and soul into the Bat, which still remains with the character to this day. With all of his different screen and voice rolls over the years, Adam has left a mark on nearly everyone who’s seen his work. So come on in and help us pay tribute to the Bright Knight! We are joined by Mark Schmidt of StratumComics.com to talk about issue five of his comic series The Threat, running on Kickstarter until June 29th. In the not too distant future, humanity is dying at apocalyptic rates. The only solution is through Recombinant DNA, which causes mutations in a small percentage of the population. These people become know as VIRALS. As cybernetically enhanced humans patrol the streets of Houston, preserving a hellish segregation, those who work for ANITEC are protected in their lives of luxury, while the rest are left to scrape together what life they can in the dangerous under-streets of the city. But there are still some, who will rise to seize a better future, becoming a THREAT to those who would keep them down. Don’t miss your chance to back this project at https://www.kickstarter.com/projects/stratumcomics/the-threat-comic-series. StratumComics.com @StratumComics @TheThreatComic CannedAirPodcast.com @CannedAirPod @Canned_Air Some royalty free music provided by TeknoAxe.com

Paul Berg, Stanford Professor of Cancer Research Emeritus and 1980 winner of the Nobel Prize in Chemistry, spoke about: his arrival at Stanford in 1959, along with six colleagues from Washington Univ. in St. Louis, who created the open, sharing environment of the new Biochemistry Department; research on genetic processes and a search to understand cancer; work developing novel tools for manipulating DNA; and his role in organizing the important, public Asilomar Conference on Recombinant DNA in 1975 where scientists evaluated risks and policy issues and agreed to voluntary limitations and guidelines.

Professor Lander reviews the process of constructing a DNA library, and then discusses how to analyze and use the information in the library.

Professor Jacks discusses the methods of recombinant DNA technology, Genetic engineering, and biotechnology, and their applications to understanding and treating disease at the molecular level.

Professor Lander discusses the development of cloning, and recombinant DNA technologies.

Enhanced Video Podcast - Part 1Aired date: 6/15/2010 9:38:00 AM Eastern Time

Enhanced Audio Podcast - Part 2Aired date: 6/16/2010 8:00:00 AM Eastern Time

Enhanced Audio Podcast - Part 2Aired date: 6/15/2010 9:38:00 AM Eastern Time

Enhanced Video Podcast - Part 2Aired date: 6/15/2010 9:38:00 AM Eastern Time

Enhanced Video Podcast - Part 1Aired date: 6/16/2010 8:00:00 AM Eastern Time

Enhanced Video Podcast - Part 1Aired date: 6/17/2010 8:30:00 AM Eastern Time

Enhanced Video Podcast - Part 2Aired date: 6/17/2010 8:30:00 AM Eastern Time

Enhanced Video Podcast - Part 2Aired date: 6/16/2010 8:00:00 AM Eastern Time

Enhanced Audio Podcast - Part 1Aired date: 6/17/2010 8:30:00 AM Eastern Time

Enhanced Audio Podcast - Part 1Aired date: 6/16/2010 8:00:00 AM Eastern Time

Enhanced Audio Podcast - Part 2Aired date: 6/17/2010 8:30:00 AM Eastern Time

Enhanced Audio Podcast - Part 1Aired date: 6/15/2010 9:38:00 AM Eastern Time

Intr Bio Fall lec : Recombinant DNA technology II

Intr Bio Fall lec : Recombinant DNA technology II

This course covers the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material. The focus of the course is on the exploration of current research in cell biology, immunology, neurobiology, genomics, and molecular medicine.

This course covers the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material. The focus of the course is on the exploration of current research in cell biology, immunology, neurobiology, genomics, and molecular medicine.

This course covers the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material. The focus of the course is on the exploration of current research in cell biology, immunology, neurobiology, genomics, and molecular medicine.

This course covers the fundamental principles of biochemistry, genetics, molecular biology, and cell biology. Biological function at the molecular level is particularly emphasized and covers the structure and regulation of genes, as well as, the structure and synthesis of proteins, how these molecules are integrated into cells, and how these cells are integrated into multicellular systems and organisms. In addition, each version of the subject has its own distinctive material. The focus of the course is on the exploration of current research in cell biology, immunology, neurobiology, genomics, and molecular medicine.

Schlechte Scanvorlage.

A method of in situ hybridization for visualizing individual human chromosomes from pter to qter, both in metaphase spreads and interphase nuclei, is reported. DNA inserts from a single chromosomal library are labeled with biotin and partially preannealed with a titrated amount of total human genomic DNA prior to hybridization with cellular or chromosomal preparations. The cross-hybridization of repetitive sequences to nontargeted chromosomes can be markedly suppressed under appropriate preannealing conditions. The remaining single-stranded DNA is hybridized to specimens of interest and detected with fluorescent or enzymelabeled avidin conjugates following post-hybridization washes. DNA inserts from recombinant libraries for chromosomes 1, 4, 7, 8, 13, 14, 18, 20, 21, 22, and X were assessed for their ability to decorate specifically their cognate chromosome; most libraries proved to be highly specific. Quantitative densitometric analyses indicated that the ratio of specific to nonspecific hybridization signal under optimal preannealing conditions was at least 8:1. Interphase nuclei showed a cohesive territorial organization of chromosomal domains, and laserscanning confocal fluorescence microscopy was used to aid the 3-D visualization of these domains. This method should be useful for both karyotypic studies and for the analysis of chromosome topography in interphase cells.

Más información de este acto

Tue, 1 Jan 1985 12:00:00 +0100 https://epub.ub.uni-muenchen.de/8491/1/8491.pdf Scriba, Peter Christian; Wood, W. G.; Tybussek, R.; Lühe, C. von der; Kraas, E.; Heidbüchel, K.; Bekemeyer, U.; Ball, P.; Müller-Esch, G.