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Welcome to Season 2 of the Orthobullets Podcast.Today's show is Foundations, where we review foundational knowledge for frontline MSK providers such as junior orthopaedic residents, ER physicians, and primary care providers.This episode will cover the topic of Fracture Healing, from our Basic Science section at Orthobullets.com.Follow Orthobullets on Social Media:FacebookInstagram TwitterLinkedInYouTube
A generation ago, a big clot in the brain meant paralysis or worse. Today, doctors can diagnose clots on AI-enabled brain scans; provide life-saving, targeted medications; or snake a catheter from a patient's groin into the brain to vacuum out the clot. If they intervene in time, they can watch speech and movement return before the sedatives wear off. How did that happen—and what's still missing?In this episode of From Our Neurons to Yours, Stanford neuroscientist and neurocritical care specialist Marion Buckwalter, MD, PhD retraces the 70-year chain of curiosity-driven research—biochemistry, imaging, materials science, AI—behind today's remarkable improvements in stroke care. She also warns what future breakthroughs are at stake if support for basic science stalls.Learn MoreBuckwalter Lab siteHistory of Stroke Care:Tissue Plasminogen Activator for Acute Ischemic Stroke (NINDS) On the development of the first-gen clot-busting drug, tPA Optimizing endovascular therapy for ischemic stroke (NINDS) On the development of mechanical clot clearance using thrombectomy.Mechanical Thrombectomy for Large Ischemic Stroke (Neurology, 2023) A literature meta-analysis shows that thrombectomy improves stroke outcomes by 2.5X, on top of 2X improvements from clot-busting drugsThe uncertain future of federal support for scienceThe Gutting of America's Medical Research: Here Is Every Canceled or Delayed N.I.H. Grant (New York Times, 2025)Trump Has Cut Science Funding to Its Lowest Level in Decades (New York Times, 2025)We want to hear from your neurons! Email us at at neuronspodcast@stanford.edu or... Send us a text!Thanks for listening! If you're enjoying our show, please take a moment to give us a review on your podcast app of choice and share this episode with your friends. That's how we grow as a show and bring the stories of the frontiers of neuroscience to a wider audience. Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.
Welcome to Season 2 of the Orthobullets Podcast.In this episode, we review the high-yield topic of Opiates & Analgesic Medications from the Basic Science section.Follow Orthobullets on Social Media:FacebookInstagramTwitterLinkedInYouTube
Welcome to Season 2 of the Orthobullets Podcast.In this episode, we review the high-yield topic of Tendons from the Basic Science section.Follow Orthobullets on Social Media:FacebookInstagramTwitterLinkedInYouTube
Paul Hoffman is the 2024 Kyoto Prize Laureate in Basic Sciences. He is an adjunct professor at the University of Victoria, has conducted groundbreaking research in the “Snowball Earth” (global freezing) hypothesis and plate tectonics occurring in the first half of the Earth's 4.6-billion-year history. After earning his doctorate from Johns Hopkins University, Hoffman served the Geological Survey of his native Canada for 24 years followed by teaching at Harvard University and conducting related research in Sub-Saharan Africa. He has geologically demonstrated the occurrence of the postulated global freeze, so-called “Snowball Earth,” which drove the rapid diversification of animals in the Cambrian period approximately 520 million years ago. Series: "Kyoto Prize Symposium" [Science] [Show ID: 39991]
Paul Hoffman is the 2024 Kyoto Prize Laureate in Basic Sciences. He is an adjunct professor at the University of Victoria, has conducted groundbreaking research in the “Snowball Earth” (global freezing) hypothesis and plate tectonics occurring in the first half of the Earth's 4.6-billion-year history. After earning his doctorate from Johns Hopkins University, Hoffman served the Geological Survey of his native Canada for 24 years followed by teaching at Harvard University and conducting related research in Sub-Saharan Africa. He has geologically demonstrated the occurrence of the postulated global freeze, so-called “Snowball Earth,” which drove the rapid diversification of animals in the Cambrian period approximately 520 million years ago. Series: "Kyoto Prize Symposium" [Science] [Show ID: 39991]
Paul Hoffman is the 2024 Kyoto Prize Laureate in Basic Sciences. He is an adjunct professor at the University of Victoria, has conducted groundbreaking research in the “Snowball Earth” (global freezing) hypothesis and plate tectonics occurring in the first half of the Earth's 4.6-billion-year history. After earning his doctorate from Johns Hopkins University, Hoffman served the Geological Survey of his native Canada for 24 years followed by teaching at Harvard University and conducting related research in Sub-Saharan Africa. He has geologically demonstrated the occurrence of the postulated global freeze, so-called “Snowball Earth,” which drove the rapid diversification of animals in the Cambrian period approximately 520 million years ago. Series: "Kyoto Prize Symposium" [Science] [Show ID: 39991]
Paul Hoffman is the 2024 Kyoto Prize Laureate in Basic Sciences. He is an adjunct professor at the University of Victoria, has conducted groundbreaking research in the “Snowball Earth” (global freezing) hypothesis and plate tectonics occurring in the first half of the Earth's 4.6-billion-year history. After earning his doctorate from Johns Hopkins University, Hoffman served the Geological Survey of his native Canada for 24 years followed by teaching at Harvard University and conducting related research in Sub-Saharan Africa. He has geologically demonstrated the occurrence of the postulated global freeze, so-called “Snowball Earth,” which drove the rapid diversification of animals in the Cambrian period approximately 520 million years ago. Series: "Kyoto Prize Symposium" [Science] [Show ID: 39991]
Welcome to Season 2 of the Orthobullets Podcast.Today's show is Podiums, where we feature expert speakers from live medical events. Today's episode will feature Dr. Matthew Pifer and is titled Sipping on my Lien!Follow Orthobullets on Social Media:FacebookInstagram TwitterLinkedIn
Welcome to Season 2 of the Orthobullets Podcast.Today's show is Podiums, where we feature expert speakers from live medical events. Today's episode will feature Dr. John Ketz and is titled Autografts - Are All Locations the Same?.Follow Orthobullets on Social Media:FacebookInstagram TwitterLinkedInYouTube
Welcome to Season 2 of the Orthobullets Podcast.Today's show is Podiums, where we feature expert speakers from live medical events. Today's episode will feature Dr. Paul Slosar and is titled Changes in Reimbursement Models - Risk Sharing Models.Follow Orthobullets on Social Media:FacebookInstagram TwitterLinkedInYouTube
On this episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., speaks with senior associate dean of academic affairs for Mayo Clinic Alix School of Medicine, Joseph Maleszewski, M.D., on the future of basic sciences in medical education.Discussion includes:· Challenges of basic science in medical education.· Differing perspectives about basic science in medical education.· Ideas of exploration for the future.
High-frequency oscillations (80 to 500 Hz) are being studied as biomarkers of epileptogenic areas in the brain, as well as markers to be used in epilepsy surgery. Dr. Cecilie Nome leads a discussion about clinical research on HFOs and areas of uncertainty, as well as the importance of basic research in helping to understand this phenomenon. Sharp Waves episodes are meant for informational purposes only, and not as clinical or medical advice.Let us know how we're doing: podcast@ilae.org.The International League Against Epilepsy is the world's preeminent association of health professionals and scientists, working toward a world where no person's life is limited by epilepsy. Visit us on Facebook, X (Twitter), Instagram, and LinkedIn.
This podcast is an oddball podcast. But you know what? It’s pretty HY to know this stuff for Step 2CK and 3. This stuff would also be very useful for a Step 1 taker as there is more emphasis on a clinical orientation with many Step 1 questions these days. I also discuss some test … Continue reading DIP Ep 569: Some Weird But Very HY Step 2/3 Basic Science Concepts (also helpful for Step 1)
In this episode, Willie Thompson ('22 cohort) and Sydney Hunt ('23 cohort) speak with Yousuf Khan ('19 cohort) about how basic science research can directly improve the lives of everyone, the role that tennis has played in his life, and his experience traveling to New Mexico for a game show.Highlights from the episode:(04:34) The story behind Yousuf's name(06:11) Growing up in the District of Columbia, Maryland, and Virginia (DMV) and attending the University of Maryland(12:05) Developing his current research interests (28:15) Facilitating the KHS conversation(30:53) Writing his Imagine a World statement and reflecting on the importance of academic humility(36:12) Participating in a Netflix game show
It's Elon Musk's world and we're just living in it. Congresswoman Debbie Wasserman Schultz talks about how he's throwing his money and weight around in Washington and whether it's a worthwhile endeavor. Plus, RFK Jr. has been on Capitol Hill trying to woo Senators as he makes his bid to be the Secretary of Health and Human Services. Former Secretary and Congresswoman Donna Shalala weighs in.
Welcome to Season 2 of the Orthobullets Podcast. Today's show is Podiums, where we feature expert speakers from live medical events. Today's episode will feature Dr. William Welch and is titled Surgical Dilemmas. This podcast is brought to you by Stryker. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube
It's simple, the reason why we're afraid to put ourselves out there is we are tired of walking into the wrong rooms with the wrong people who do not see our value in potential.
Drs. Gerard Slobogean, Zach Working and Justin Haller review the highlights of the Basic Science Focus Forum from the 2024 OTA Annual Meeting. Live from the 2024 OTA Annual Meeting. For additional educational resources visit OTA.org
Welcome to Season 2 of the Orthobullets Podcast. Today's coinflip episode is titled "Private Equity and Transactions in Orthopaedics: Basics, Trends, and Future Predictions." It will be sponsored by the IOEN Vail Arthroplasty Course 2025, which will take place from Jan 17th to Jan 19th in Vail, CO. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube
JASN encourages investigators to submit their basic science original research to the journal. Editor-in-Chief Rajnish Mehrotra and Deputy Editors Alessia Fornoni and David H. Ellison discuss the types of basic research that JASN publishes.
Pluripotent stem cells are defined, in part, by their potential to generate cell types from all three embryonic germ layers. However, it is well known within the field that there is variability in developmental potential between cell lines. This phenomenon, sometimes referred to as lineage bias, is manifest in a variable response of individual cell lines to induction of differentiation into a specific germ layer lineage. Although lineage bias in pluripotent stem cells has been reported for some years, we do not fully understand its molecular basis, or its implications for normal development. The guests on today's program studied functional variation in human PSC lines as they progress through neurectoderm versus mesendoderm lineages and fore- versus hind-brain development. They will discuss the origin and consequences of inter-individual variation in the early events orchestrating human neural development, the extent to which such variation might impact on adult health and disease, and how it might be exploited in stem cell therapy. GuestsRon McKay is the Director of Basic Science at the Lieber Institute and has appointments in multiple departments and the McKusick-Nathans Institute of Genetic Medicine at the Johns Hopkins School of Medicine, USA. He currently serves as a member of the Stem Cell Reports Editorial Board. Suel-Kee Kim is an Associate Research Scientist in the Department of Neuroscience at Yale University School of Medicine, USA. Seungmae Seo is an Assistant Professor at University of Maryland Eastern Shore, USA. Seungmae is a former ISSCR Merit and Travel Award Winner. HostMartin Pera, Editor-in-Chief, Stem Cell Reports and The Jackson Laboratory@martinperaJAXSupporting ContentIndividual variation in the emergence of anterior-to-posterior neural fates from human pluripotent stem cells, Stem Cell ReportsAbout Stem Cell ReportsStem Cell Reports is the open access, peer-reviewed journal of the International Society for Stem Cell Research (ISSCR) for communicating basic discoveries in stem cell research, in addition to translational and clinical studies. Stem Cell Reports focuses on original research with conceptual or practical advances that are of broad interest to stem cell biologists and clinicians.X: @StemCellReportsAbout ISSCRWith nearly 5,000 members from more than 80 countries, the International Society for Stem Cell Research (@ISSCR) is the preeminent global, cross-disciplinary, science-based organization dedicated to stem cell research and its translation to the clinic. The ISSCR mission is to promote excellence in stem cell science and applications to human health.ISSCR StaffKeith Alm, Chief Executive OfficerYvonne Fisher, Managing Editor, Stem Cell ReportsKym Kilbourne, Director of Media and Strategic CommunicationsJack Mosher, Scientific AdvisorVoice WorkBen Snitkoff
Prof. Brit Mollenhauer shares her excitement about basic science, including biomarker research, and how she believes MDS's diversity can help foster more collaboration between clinicians and basic scientists.
The connection between your psychology and your health, and how to work with it.Ellen J. Langer is the author of eleven books, including the international bestsellerMindfulness, which has been translated into fifteen languages, and Counterclockwise:Mindful Health and the Power of Possibility. Most recently, she is the author of TheMindful Body: Thinking Our Way to Chronic Health.Langer is the recipient of, among other numerous awards and honors, a GuggenheimFellowship, the Award for Distinguished Contributions to Psychology in the PublicInterest from the American Psychological Association, the Award for DistinguishedContributions of Basic Science to the Application of Psychology from the AmericanAssociation of Applied and Preventive Psychology, and the Adult Development andAging Distinguished Research Achievement Award from the American PsychologicalAssociation.She is the author of more than 200 research articles and her trailblazing experiments insocial psychology have earned her inclusion in The New York Times Magazine's “Yearin Ideas” issue. A member of the psychology department at Harvard University and apainter, she lives in Cambridge, Massachusetts.In this episode we talk about:The power of placebosWhy she isn't a fan of positive thinking as it is talked about in new age circlesHer version of mindfulness, which is quite different from the version we usually talk about here on the show, which comes out of BuddhismPsychological treatments for chronic illness Smart strategies for reframing aging. Why the world would be boring if you knew it allWhat she means by her concept of a “mindful utopia”And her favorite one liners Related Episodes:The Science Of Manifestation: Can This Stanford Neuroscientist Convince A Skeptical Dan To Give It A Shot? | Dr. James R. DotyHow to Get the Wisdom of Old Age Now | Dilip Jeste Tripping Out with a Legend: Jon Kabat-Zinn on Pain vs. Suffering, Rethinking Your Anxiety, and the Buddha's Teaching in a Single SentenceSign up for Dan's weekly newsletter hereFollow Dan on social: Instagram, TikTokTen Percent Happier online bookstoreSubscribe to our YouTube ChannelOur favorite playlists on: Anxiety, Sleep, Relationships, Most Popular EpisodesFull Shownotes: https://happierapp.com/podcast/tph/ellen-langer-832See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Welcome to Season 2 of the Orthobullets Podcast. Today's show is Podiums, where we feature expert speakers from live medical events. This episode will feature Dr. Gregory Basil, and is titled The Use of Objective Activity Data to Model Outcomes. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube
In this podcast, I spend time discussing more than 50 basic science concepts across antibiotics, genetics, and cell biology that show up very frequently on the USMLE Step 2CK and Step 3 exams. Audio Download
Ellen Langer is a professor in the Psychology Department at Harvard University. In 1981, she became the first woman ever to be tenured in psychology at Harvard. Dr. Langer has described her work on the illusion of control, aging, decision-making, and mindfulness theory in over 200 research articles and six academic books. Her work has led to numerous academic honors including a Guggenheim Fellowship, the Award for Distinguished Contributions to Psychology in the Public Interest of the American Psychological Association, the Distinguished Contributions of Basic Science to Applied Psychology award from the American Association of Applied & Preventive Psychology, the James McKeen Cattel Award, and the Gordon Allport Intergroup Relations Prize. In this conversation today, Ellen & I discuss: 00:00 - The Power of the Human Mind 07:57 - How The Mind Can Heal the Body 10:49 - Perceptions of time influence healing 17:23 - Challenging fixed beliefs 28:02 - Stress Management and Decision-Making 32:04 - Embracing the imperfect decision 39:18 - The True Power of Mindfulness 44:49 - Re-write the rule book 55:00 - What makes a life worth living? 56:00 - Connect with Ellen Links: https://scholar.harvard.edu/langer/biocv http://ellenlanger.com Buy The Mindful Body: https://www.amazon.co.uk/Mindful-Body...
In this episode, we review the high-yield topic of Opiates & Analgesic Medications from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube
In this episode, we review the high-yield topic of Gout from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube
In this episode, we review the high-yield topic of Tendons from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube
In this episode, we review the high-yield topic of Muscle Biology & Physiology from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube
In this episode, we review the high-yield topic of Bone Growth Factors from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube
In this episode, we review the high-yield topic of Level of Evidence from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube
In this episode, we review the high-yield topic of Rehab & Prosthetics from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube
Ellen J. Langer is the author of eleven books, including the international bestseller Mindfulness, which has been translated into fifteen languages, and Counterclockwise: Mindful Health and the Power of Possibility. Most recently, she is the author of The Mindful Body: Thinking Our Way to Chronic Health. Langer is the recipient of, among other numerous awards and honors, a Guggenheim Fellowship, the Award for Distinguished Contributions to Psychology in the Public Interest from the American Psychological Association, the Award for Distinguished Contributions of Basic Science to the Application of Psychology from the American Association of Applied and Preventive Psychology, and the Adult Development and Aging Distinguished Research Achievement Award from the American Psychological Association. She is the author of more than 200 research articles and her trailblazing experiments in social psychology have earned her inclusion in The New York Times Magazine's “Year in Ideas” issue. A member of the psychology department at Harvard University and a painter, she lives in Cambridge, Massachusetts. Contact Info: Website: https://www.ellenlanger.me/ Social Media links https://www.linkedin.com/in/ellenjlanger/ https://www.facebook.com/EllenJLanger https://twitter.com/ellenjl https://www.instagram.com/ellenjlanger/ How We Can Help You Close More Deals: Gitomer Books and Courses Here Sales Mastery Program Here Gitomer Sales Certification Here Free Webinar Friday July 5! Register for the upcoming Gitomer Sales AI Revolution FREE Webinar here
In this episode, we review the high-yield topic of Complex Regional Pain Syndrome (CRPS) from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube --- Send in a voice message: https://podcasters.spotify.com/pod/show/orthobullets/message
In this episode, we review the high-yield topic of Clinical Trial Design from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube --- Send in a voice message: https://podcasters.spotify.com/pod/show/orthobullets/message
In this episode, we review the high-yield topic of Ethics in Orthopaedic Practice from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube --- Send in a voice message: https://podcasters.spotify.com/pod/show/orthobullets/message
In this episode, we review the high-yield topic of Bone Cells from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube --- Send in a voice message: https://podcasters.spotify.com/pod/show/orthobullets/message
In this episode, we review the high-yield topic of Rickets from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube --- Send in a voice message: https://podcasters.spotify.com/pod/show/orthobullets/message
In this episode, we review the high-yield topic of Fracture Healing from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube --- Send in a voice message: https://podcasters.spotify.com/pod/show/orthobullets/message
In this episode, we review the high-yield topic of Bisphosphonates from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube --- Send in a voice message: https://podcasters.spotify.com/pod/show/orthobullets/message
In this episode, we review the high-yield topic of Wear & Osteolysis Basic Science from the Recon section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube --- Send in a voice message: https://podcasters.spotify.com/pod/show/orthobullets/message
In this episode, we review the high-yield topic of Anticoagulation Medications from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube --- Send in a voice message: https://podcasters.spotify.com/pod/show/orthobullets/message
In this episode, we review the high-yield topic of Antibiotic Classification & Mechanism from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube --- Send in a voice message: https://podcasters.spotify.com/pod/show/orthobullets/message
In this episode, we review the high-yield topic of Articular Cartilage from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube --- Send in a voice message: https://podcasters.spotify.com/pod/show/orthobullets/message
In this episode, we review the high-yield topic of Bone Grafting from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube --- Send in a voice message: https://podcasters.spotify.com/pod/show/orthobullets/message
In this episode, we review the high-yield topic of Orthopaedic Implants from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube --- Send in a voice message: https://podcasters.spotify.com/pod/show/orthobullets/message
In this episode, we review the high-yield topic of Material Properties from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube --- Send in a voice message: https://podcasters.spotify.com/pod/show/orthobullets/message
In this episode, we review the high-yield topic of Rheumatoid Arthritis from the Basic Science section. Follow Orthobullets on Social Media: Facebook Instagram Twitter LinkedIn YouTube --- Send in a voice message: https://podcasters.spotify.com/pod/show/orthobullets/message