Podcasts about 2M

Your marketing works hard to attract leads—so why aren't you getting the sales results you expect from them? The truth is, the biggest obstacle to sales often isn't your leads choosing your competitors—it's hidden inside your own business. From unintentional roadblocks to well-meaning employees who accidentally push customers away, this episode uncovers the subtle (and not-so-subtle) ways companies sabotage their own success. If you want to make it easier for customers to say yes, this is a must-listen.Get the Free Sales Prevention Checklist: Discover the top ways businesses unknowingly block their own sales—and how to fix them. ➤ Download the checklist hereGET MORE MARKETING & SALES TOOLS:Are you interested in becoming the published author of a powerful book to help you attract more ideal clients and set you apart from the competition? Imagine holding your own book in your hands as quickly as 3-6 weeks without you ever having to write a word. We do all the work, you get all the glory! Find out how we Capture Your Genius at our sister publishing house Lunch Break Books - powerful books for entrepreneurs with big growth goals.Are you subscribed to Marketing Gold? Get more marketing tools, tips and strategies delivered to your inbox most Mondays. Sign up here.Is your business doing $2M+ and you're ready to take it to the next level? We'll show you how. Get your free marketing roadmap by taking the Client Stampede Assessment. It's fast, free (Value $197) and your 20+ page report is emailed to you instantly.Enjoying the podcast? You'll love the audio book. Get The Client Stampede audio book on Amazon.

On this week's episode of the Massively OP Podcast, Bree and Justin talk about the ups and downs of investor funding with online games, including Project Ghost, the Warhammer MMO, Pantheon, and Innsmouth Mysteries. Other topics include Necesse's runaway success, BitCraft's new patch, a consolation content update for New World, and the growing trend of cozy gaming. It's the Massively OP Podcast, an action-packed hour of news, tales, opinions, and gamer emails! And remember, if you'd like to send in your question to the show, use this link. Show notes: Intro Adventures in MMOs: LOTRO, WoW, RIFT, GW2 News: Project Ghost is officially dead as is that Warhammer MMO News: New World gets a consolation update News: Pantheon and Innsmouth Mysteries receive welcome funding News: Necesse sells 2M units, BitCraft puts out new update Mailbag: What do we think of Petit Planet and cozy games? Outro Other info: Podcast theme: "Forest Caves" from Necesse Your show hosts: Justin and Bree Listen to Massively OP Podcast on iTunes, Stitcher, Player FM, TuneIn, iHeartRadio, Pocket Casts, Amazon, and Spotify Follow Massively Overpowered: Website, Twitter, Facebook, Twitch If you're having problems seeing or using the web player, please check your flashblock or scriptblock setting.

Your Manufacturing Decisions Are Costing You More Than You ThinkEvery bioreactor decision. Every scale-up choice. Every facility investment. They're all silently writing checks your process might not be able to cash.The difference between a profitable biologics program and one that bleeds capital? Process economic modeling, the analytical framework that reveals exactly where your money goes and why.In this episode of the Smart Biotech Scientist Podcast, David Brühlmann talks with Niklas Jungnelius, Process Modeling Leader at Cytiva, who has spent 25+ years decoding the economics of biologics manufacturing for biotech companies navigating billion-dollar decisions.Niklas reveals the hidden cost drivers most teams miss, the surprising economics behind fed-batch vs. continuous processing, and why your facility choice at intermediate scale could make or break your business case.Episode Highlights:What process economic modeling is and how it differs from mechanistic modeling (06:40)Main cost drivers in biologics and biosimilars manufacturing, and their direct and indirect impacts on patient pricing (09:21)The role of manufacturing scale and productivity in driving down costs, and how facility type (stainless steel vs single-use) affects labor, flexibility, and investment (11:51)Trade-offs between single-use and stainless steel facilities at intermediate production scales (15:07)Key differences in cost and efficiency between fed-batch and fully continuous manufacturing, including productivity limitations and capital/expenditure implications (16:20)The impact of resin lifetime and under-utilization on clinical manufacturing costs (19:51)Hidden or less quantifiable costs such as facility flexibility, excess capacity, safety margins, and the importance of realistic assumptions in economic modeling (20:20)This is a grounded discussion with practical takeaways for biotech scientists seeking clarity in the complex terrain of process economics. Part two of this conversation will focus on sustainability modeling and the latest technologies reshaping bioprocessing economics.Ready to see how process modeling could transform your approach and protect your bottom line? Listen to the episode and rethink your next investment.Connect with Niklas Jungnelius:LinkedIn: www.linkedin.com/in/niklas-jungneliusCytiva website: www.cytivalifesciences.com/en/usNext step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/call

Brandon Dawson is 1 of youngest to ring NY Stock Exchange Bell. Sold 1st Business at 29 for 38.2M dollar. Sold Last Business for 151M dollar. Business Scaling Expert, Precision Health Optimizer. Top 3 Value Bombs 1. Success is not luck but a choice. Anyone who decides to take consistent action and never quit can build something extraordinary. 2. Your business should self-fund growth. Learn to force your business to make money before turning to investors. 3. Exiting is not just selling. It's about designing your business so it thrives without you, maximizing value and freedom. Check out Brandon's website - Brandon Dawson Website Sponsors HighLevel - The ultimate all-in-one platform for entrepreneurs, marketers, coaches, and agencies. Learn more at HighLevelFire.com. NetSuite - Get the business guide, "Demystifying AI", for free, at Netsuite.com/fire. Framer - Ready to design, iterate, and publish all in one tool? Start creating for free at Framer.com/design, and use code FIRE for a free month of Framer Pro! Rules and Restrictions May Apply.

In this two-part Dating Detectives story, we meet Jessica, a dog groomer and accomplished show-dog handler whose grief after her father's death left her vulnerable to a “Show Dogfish". What begins as comforting late-night calls with Dylan, a fellow competitor in the dog show world, escalates into love-bombing, a sudden proposal, a courthouse wedding, and controlling red flags—from secretive money moves, to keeping her car keys. As Jessica juggles her dogs, grief, and mounting estate logistics, a crisis at home collides with a shocking knock at her door: a process server tied to a $2M fraud case naming Dylan. Click here to join our Patreon! For only $5 a month you will get 2 extra episodes a month, monthly virtual live events, and access to our community page. And now for $9 a month you can get all of that, plus ad free episodes!If you've been dogfished and want to share your story on the show, email investigate@thedatingdetectivespodcast.com or contact us through our website using this linkThis episode is sponsored by SKIMS. Shop the SKIMS Fits Everybody Collection at SKIMS.com. After you place your order be sure to let them know we sent you by filling out the survey!This episode is sponsored by Miracle Made. Get silver-infused, bacteria-fighting, temperature-regulating sheets and towels at TryMiracle.com/TDD and use code TDD to save over 40% and claim a FREE 3-piece towel set.Make this spring your most delicious yet with Green Chef. Head to greenchef.com/50datingdetectives and use code 50datingdetectives to get 50% off your first month, then 20% off for two months with free shipping.This episode is sponsored by Wayfair. Refresh your home for less. Shop back-to-routine deals by visiting Wayfair.com.Take control of your data today. Get 20% off your DeleteMe plan by visiting joindeleteme.com/datingdetectives and using the promo code TDD at checkout. Get control of your finances with Monarch Money. Use code DATING at MonarchMoney.com in your browser (not app) for half off your first year!***The following Program contains names, places and events that have been anonymized or fictionalized for the purposes of protection and safety. The following Program is provided for entertainment purposes only and any commentary from the hosts are strictly conjecture and should not be held as making any definitive statements about the truth or identity of any particular individuals or circumstances.If you or a loved one are involved in an abusive relationship, please call the National Domestic Violence Hotline at 1-800-799-7233 for support.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Linktree: ⁠https://linktr.ee/Analytic⁠Join The Normandy For Additional Bonus Audio And Visual Content For All Things Nme+! Join Here: ⁠https://ow.ly/msoH50WCu0K⁠Analytic Dreamz unpacks Sin Bandera's timeless “Que Lloro” on Notorious Mass Effect. The Mexican-Argentine duo—Leonel García (b. 1975) and Noel Schajris (b. 1974)—formed in 2000, bonding over piano-guitar harmonies and emotive pop-ballads. Their 2001 debut won Latin Grammys; 2003's De Viaje (#1 Billboard Top Latin Albums 16 weeks, multi-platinum) birthed “Que Lloro,” a vulnerability-drenched breakup anthem written by García and produced by Áureo Baqueiro. Peaking #10 Hot Latin Songs with 11.2M weekly impressions (2004), it now boasts 200M+ Spotify streams, 150M+ YouTube views—plus 50M from the 2007 Reik duet. Streaming surged 40% post-2016 reunion, hitting 10M+ annual equivalents; 60% from Spotify/YouTube, 25% Apple Music LatAm. Karaoke catalogs add 20% ancillary sales; 100K+ fan covers generate 5M indirect views. Telenovela syncs lifted 2003 Mexico physicals 30%. Streams spike 25% in February (Valentine's) and November (LatAm breakup season). Fueled by 2025's 25th anniversary tour, “Que Lloro” remains Latin pop's therapeutic heartbreak staple and Sin Bandera's enduring entry point. Analytic Dreamz details stats, cultural longevity, and long-tail dominance. Support this podcast at — https://redcircle.com/analytic-dreamz-notorious-mass-effect/donationsAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy

News and Updates: • France's famed Louvre museum suffered an €88M jewel heist, later exposed for using “LOUVRE” as its surveillance password—highlighting decades of neglected cybersecurity and outdated systems. • Two U.S. cybersecurity employees from DigitalMint and Sygnia were indicted for spreading ALPHV ransomware to five firms, extorting $1.2M before one confessed and both were fired. • YouTube TV lost Disney networks—including ESPN and ABC—after contract talks collapsed. Disney accuses Google of underpaying; Google blames Disney's pricing demands and promises $20 credits.

On this week's Money Matters, Scott and Pat open the show with a look at the Magnificent Seven stocks. Is this tech dominance a warning sign or just the new market normal? They unpack what this concentration means for index investors and why historical perspective matters. Next, they take a call from a 56-year-old tech professional navigating a surprise layoff and considering early retirement. With over $2M in assets and plans to relocate, they walk through whether he can afford to stop working—or if some part-time income is essential. It's a timely breakdown of early retirement math, real estate moves, and RSU liquidation strategy. The episode wraps with two strong planning discussions: a state employee navigating Roth vs. traditional 401(k)/457 contributions, and a retiree using a "bucket strategy" who wants feedback on portfolio structure. Scott and Pat debate risk tolerance, rebalancing, and why flexibility is key in retirement income planning. If you're exploring early retirement, weighing Roth contributions, or fine-tuning your investment drawdown plan—this episode is packed with actionable insights. Join Money Matters:  Get your most pressing financial questions answered by Allworth's co-founders Scott Hanson and Pat McClain live on-air! Call 833-99-WORTH. Or ask a question by clicking here.  You can also be on the air by emailing Scott and Pat at questions@moneymatters.com. Download and rate our podcast here.

USE MY 5-STEP LITMUS TEST TO SEE THE PROFITABILITY OF A POTENTIAL PROPERTY: https://strlikethebest.com/litmuspodQ4 2025 Market Update: What's Actually Working Right NowMost people think high-income professionals are buying Airbnbs for cash flow. They're wrong.In this episode, Michael and Liz reveal the real reason why employees at Meta, Amazon, Blackstone, and Goldman Sachs are aggressively buying $750K-$1.5M short-term rental properties and it has everything to do with the tax code.We break down:How to legally offset $300K+ in W2 income with a single property purchase (and why paying 40% in taxes is optional if you know what you're doing)The markets actually producing results in 2025 (Tennessee, Colorado, Pennsylvania) and which expensive Northeast markets are complete trapsA real $2M property case study where the owner is leaving $50K+ on the table annually through basic pricing mistakes (this happens more than you think)Why this only works as a long-term hold strategy, and why trying to flip your way through this will get you destroyed by the IRSThe difference between markets with "good regulation" versus those that will make your investment impossible to operateThe bottom line: If you're making $200K-$650K in W2 income, taxes are your biggest expense, bigger than your mortgage, bigger than anything else. This episode shows you exactly how to turn that expense into your biggest wealth accelerator.This is what they don't teach you in business school.LEARN MY STR INVESTING & STRATEGIES

This week Lauren and Keith discuss a very elaborate but stupid hesit.Sources: The Sneak Podcast: Season 1Let's Go To Court: Episode 34 The Brink's Car Robbery & The Assistant Who Ended Her Boss's Ponzi SchemeMedium: An Almost Ingenious Plan by AJ WisemanDavid Kushner.com: The All-American Bank Heist by David KushnerUSA Today: How an Idaho football player became a bank robber by Martin RogersHistory Link: "D. B. Tuber" robs an armored car guard at the Bank of America in Monroe on September 30, 2008. by Phil DoughertyFBI: Seattle Division Press Release: Former High School Star Athlete Sentenced to Prison for Armored Car Robbery Defendant Used Ad on Craigslist and Flotation Device to Make Escape Following Monroe RobberyDepartment of Justice: Operators Of Nationwide Sports And Pokémon Trading Card Fraud Arrested2 WA men accused of selling fake Pokémon, sports cards in $2M scheme by Charmin FlojoWikipedia

Andrẽs Merlos is a comedian, filmmaker, and producer based in Chicago, IL. Perhaps you have heard of the masterpiece, 'Coconut Cruise', presented in conjunction with 773 Studios & High TV Chi!

Un autre départ chez les conservateurs. STM: la patience des usagers mise à rude épreuve. Réduction des seuils d’immigration. Contestation de la loi 2. 2M$ pour contester la Loi sur la laïcité. Québec solidaire choisira le successeur de Gabriel Nadeau-Dubois ce week-end. Des bulletins de nouvelles générés par l’intelligence artificielle. Tour de la planète sport avec Justine St-Martin. Tout savoir en quelques minutes avec Alexandre Dubé, Isabelle Perron et Mario Dumont. Regardez aussi cette discussion en vidéo via https://www.qub.ca/videos ou en vous abonnant à QUB télé : https://www.tvaplus.ca/qub ou sur la chaîne YouTube QUB https://www.youtube.com/@qub_radioPour de l'information concernant l'utilisation de vos données personnelles - https://omnystudio.com/policies/listener/fr

Un autre départ chez les conservateurs. STM: la patience des usagers mise à rude épreuve. Réduction des seuils d’immigration. Contestation de la loi 2. 2M$ pour contester la Loi sur la laïcité. Québec solidaire choisira le successeur de Gabriel Nadeau-Dubois ce week-end. Des bulletins de nouvelles générés par l’intelligence artificielle. Tour de la planète sport avec Justine St-Martin. Tout savoir en quelques minutes avec Alexandre Dubé, Isabelle Perron et Mario Dumont. Regardez aussi cette discussion en vidéo via https://www.qub.ca/videos ou en vous abonnant à QUB télé : https://www.tvaplus.ca/qub ou sur la chaîne YouTube QUB https://www.youtube.com/@qub_radioPour de l'information concernant l'utilisation de vos données personnelles - https://omnystudio.com/policies/listener/fr

Cell and gene therapies are transforming modern medicine, but their path to market is fast and complex. They often jump from small trials to global launch at record speed, putting pressure on analytics, supply chains, and partnerships. Success depends on making smart choices about what to build in-house and what to entrust to expert partners.Daniel Galbraith knows these challenges intimately. With decades of hands-on experience and as Chief Scientific Officer at Solvias, Daniel has witnessed firsthand the seismic shifts in analytical development for advanced therapies. He's been on every side of the table: troubleshooting manufacturing snags, scaling up from a single batch to hundreds per month, and guiding companies as they choose between in-house development and relying on a CRO's muscle.In this episode:How evolving cell and gene therapy timelines are driving the need for true CRO-drug developer partnerships (00:00)The unique challenges of scaling CMC analytics from early trials to global commercialization (02:51)Key pitfalls to avoid when outsourcing to CROs—especially around communication, scheduling, and troubleshooting (06:26)Deciding whether to build capabilities in-house or outsource to a CRO, and how to find the right balance for your team (08:41)The critical importance of strong project management for juggling relationships between developer, CRO, and CDMO (09:51)Daniel's perspective on the future of combination therapies and what the analytical landscape will demand of CROs (13:33)Practical advice for building transparent, open CRO partnerships that support your goals (15:21)Facing scale-up challenges or a first CGT launch? This conversation shares practical strategies to advance therapies efficiently.Tune in for actionable insights on CMC, outsourcing, and analytical development.Connect with Daniel Galbraith:LinkedIn: www.linkedin.com/in/daniel-galbraith-26a6138Solvias website: www.solvias.comEmail: daniel.galbraith@solvias.comNext step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/callPreparing for your IND? Grab our Startup Founder CMC Dashboard in Notion to help you track tasks, timelines, and risks in one place at https://stan.store/SmartBiotech/p/discovertoind-cmc-dashboard-for-startup-founders

From Uber shifts to building Legacy Wealth Academy: In this episode of the Life Insurance Academy Podcast, we sit down with Mark Cassara (Frisco, TX)—a financial strategist and educator who's grown an audience of 2M+ across TikTok, Instagram, YouTube, and Facebook— to unpack how short-form, value-first content can build trust, generate inbound leads, and fuel a thriving virtual practice focused on IULs, executive bonus plans, and retirement strategies. Mark shares: How he went from 3 jobs to full-time in 6–8 months—and then doubled his income year over year The content system (and cadence) that took him from 0 to 100K+ followers in months Why short-form "give, give, give" education beats hard selling Clear, plain-English explanations of IULs (upside potential, 0% floor, liquidity, and common pitfalls) Real-world client use cases: enhanced liquidity riders, premium deposit accounts, and executive strategies How he onboards agents with a social media bootcamp so they can win faster If you're an agent, leader, or entrepreneur who wants to build a pipeline without buying leads—and serve families with clarity and confidence—this one's for you.    

How does a professional touring musician go from the recording studio to building a $1.2M recruiting firm without ever making a single cold call? In this episode of The Resilient Recruiter, Justin Levinson, founder of Coming Up Creative, reveals how he blended creativity, authenticity, and smart systems to grow a seven-figure recruitment business serving the world's top entertainment and gaming brands. Justin's story is proof that success in recruitment isn't about grinding harder - it's about thinking differently. You'll hear how he built a global team, automated outreach without losing the human touch, and turned every conversation into an opportunity. Listen to discover: How creative thinking helped Justin scale to $1.2M in billings The “anti-campaign” approach that fills his calendar with warm leads Why branding and design matter more in creative industries How to build trust, credibility, and inbound clients without cold calls The diversification strategy that kept his firm thriving through Hollywood strikes If you've ever wondered whether it's possible to grow a high-performing recruiting business without endless prospecting, this episode is your blueprint. Connect with Justin Levinson LinkedIn: Justin Levinson Website: Coming Up Creative Connect with Mark Whitby FREE strategy session: www.recruitmentcoach.com/strategy-session LinkedIn: Mark Whitby

AlabamaGovernor Ivey to release $2M in state emergency funds to food banks in ALCongressman Strong says traditional Democrats need to flee the party due to leftists and government shutdownMike Blackmon to challenge Randy Brock in 2026 Conecuh County sheriff's raceA fourth lawsuit is filed against Ukrainian truck driver who crashed in Thomasville killing 2 peopleNew mayor of Mobile creates a direct reporting system for his administrationSen. Tuberville honors 2 veterans in AL ahead of Veteran's DayNationalSocialist Democrat Zohran Mamdani wins mayoral race in NYC Virginia governorship goes to Democrat Abigail SpanbergerUPS cargo plane crashes and burns at Louisville airport in KentuckyTransportation Secretary says airspace to be shutdown if controllers don't get paidTX congressman offers articles of impeachment re: District Judge BoasbergSCOTUS to hear oral arguments today regarding tariffs issued by Trump under Emergency Economic Power Act

Roth Conversion Secrets Your Financial Advisor Won't Tell You #retirementplanning #retirement #financialplanning #podcast If you've built a portfolio between $2M and $7M, and you're either retired or nearing retirement, this video is for you. I'm Andrew Nida, President of Asset Management Group, Inc., and in this video you'll get a step-by-step, rules-based guide to converting your pre-tax retirement assets into a Roth the right way. No hype. No generalities. Just actionable strategy. You'll learn: The five critical factors we always review for clients in your asset-range (burn rate, age & RMD timeline, future tax rate, estate impact, bracket/IRMAA guardrails). The rules and traps you absolutely cannot ignore (taxable income of a conversion, five-year rule, state tax issues, Medicare surcharge risk). A multi-step plan built for those with $2M–$7M: how to measure, model, convert, monitor. Why 2025-2026 may be one of the last big windows for this strategy (thanks to recent tax law changes). Follow us onX.com: https://x.com/AMGinc_ATLInstagram: https://www.instagram.com/assetmanagementgroupinc/LinkedIn: https://www.linkedin.com/company/amgincatl/Facebook : https://www.facebook.com/beyondtomorrowpodcastWebsite: https://www.assetmg-inc.com/YouTube: https://www.youtube.com/@assetmanagementgroupincTikTok : https://www.tiktok.com/@assetmanagementgroupincBlog: https://www.assetmg-inc.com/blogDisclosureEducational content only. Not tax, legal, or investment advice. Tax laws can change. Consult your CPA or advisor about your specific situation.roth conversion,Roth Conversion Secrets,finance,retirement planning,roth ira,personal finance,investing,financial planning,conversion,retirement income,social security,taxes,how to invest money,401k,financial advisor,tax strategies,estimated taxes explained,dave ramsey,financial education,ira,IRS,roth ira explained,roth ira vs traditional ira,how to make money,retirement,dividend investing,tax free,medicare,one big beautiful bill,Andrew Nida,Podcast,AMG

Sales slowing down? Don't panic—and definitely don't reach for the discount lever.In this episode, I'm unpacking one of the most damaging (yet common) knee-jerk reactions in business: cutting prices when sales stall. It's understandable, but almost always the wrong move. Discounting not only trains your buyers to wait for a deal—it erodes your brand and drags you straight into commodity pricing hell.GET MORE MARKETING & SALES TOOLS:Are you interested in becoming the published author of a powerful book to help you attract more ideal clients and set you apart from the competition? Imagine holding your own book in your hands as quickly as 3-6 weeks without you ever having to write a word. We do all the work, you get all the glory! Find out how we Capture Your Genius at our sister publishing house Lunch Break Books - powerful books for entrepreneurs with big growth goals.Are you subscribed to Marketing Gold? Get more marketing tools, tips and strategies delivered to your inbox most Mondays. Sign up here.Is your business doing $2M+ and you're ready to take it to the next level? We'll show you how. Get your free marketing roadmap by taking the Client Stampede Assessment. It's fast, free (Value $197) and your 20+ page report is emailed to you instantly.Enjoying the podcast? You'll love the audio book. Get The Client Stampede audio book on Amazon.

Orlando City SC legend Pedro Gallese ("El Pulpo") has officially departed the club following the conclusion of his contract after six memorable seasons. Join us as we remember his incredible save-stopping heroics, record-breaking tenure, and the controversial details surrounding his exit.However, the MLS roster continues to change! We'll dive deep into the next potential departures as the club looks to clear significant salary cap space. Who is on the "chopping block" at Orlando City? We analyze the financial implications of Gallese's $1.2M contract and the future of the goalkeeper position with Javier Otero as a potential starter. Plus, we break down the latest OCSC transfer rumors for incoming players and the club's plan to restructure the roster for the upcoming season!#OrlandoCity #PedroGallese #MLS

Rob Dietz sold $25.2M worth of cars on Bring-a-Trailer. How and why did he do it? What are the changes he sees coming the car market? All that and more! https://www.instagram.com/wob_cars/ https://wobcars.com/author/wob/ https://www.businessinsider.com/heres-how-i-sold-252-million-in-cars-on-bring-a-trailer-2022-1 Recorded October 28, 2025  Show Notes:SmallsFor a limited time get 60% off your first order when you head to smalls.com/tire RulaThousands of guys have already used Rula to finally get the care they needed. Don't keep putting it off -  go to Rula.com/tire and get started today. Take the first step, get connected, and take control of your mental health. FactorEat smart at FactorMeals.com/tire50off and use code tire50off to get 50% off your first box, plus Free Breakfast for 1 Year. Get delicious, ready-to-eat meals delivered—with Factor.  New merch! Grab a shirt or hoodie and support us! https://thesmokingtireshop.com/ Use Off The Record! and ALWAYS fight your tickets! For a 10% discount on your first case go to https://www.offtherecord.com/TST Want your question answered? Want to watch the live stream, get ad-free podcasts, or exclusive podcasts? Join our Patreon: https://www.patreon.com/thesmokingtirepodcast Instagram:https://www.Instagram.com/thesmokingtirehttps://www.Instagram.com/therealzackklapman   Want your question answered? Want to watch the live stream, get ad-free podcasts, or exclusive podcasts? Join our Patreon: https://www.patreon.com/thesmokingtirepodcast Use Off The Record! and ALWAYS fight your tickets! Enter code TST10 for a 10% discount on your first case on the Off The Record app, or go to http://www.offtherecord.com/TST. Watch our car reviews: https://www.youtube.com/thesmokingtire Tweet at us!https://www.Twitter.com/thesmokingtirehttps://www.Twitter.com/zackklapman Instagram:https://www.Instagram.com/thesmokingtirehttps://www.Instagram.com/therealzackklapman

HighlightsThe most important shift in business isn't software, hustle, or the next hire — it's identity (owner vs. operator).“Herb's Burger Shack” vs. McDonald's: why systems, not a superior burger, scaled a global enterprise.The Operator's Trap: “no one can do it like me,” “I can't afford help,” and becoming the most expensive employee in your own company.Growth makes operator-mode more miserable (busy at $2M; drowning at $10M).Owners still feel fear — they act anyway and optimize for a better quality of problems.The Expensive Prison you built: every “I'll just do it” brick locks you in; structure is the escape hatch.Bottom line: become the architect, not the bottleneck. That's where freedom, scale, wealth, and health coexist.Timestamps00:03 — Why the biggest lever is identity, not software or hustle.01:07 — The “same year 45 times” warning.01:31 — Herb's Burger Shack vs. McDonald's (systems & real estate > burgers).03:46 — Operator belief loop: “No one will do it as well as me.”04:14 — Case study: $7M builder who approves everything and eats zero family dinners.05:00 — 80% psychology, 20% strategy; owners act in spite of fear.06:08 — “The Expensive Prison” you constructed with every “I'll just do it.”08:12 — The ask: will you keep flipping burgers, or build a franchise?08:33 — DM @RodricLenhart with your takeaways.Pull Quotes“If you're still thinking like an operator and not an owner, you'll default to firefighting.”“McDonald's isn't a burger company — it's a systems and real-estate company.”“Most entrepreneurs don't own businesses — they own prisons.”“Be the architect, not the bottleneck.”Call to ActionDM @RodricLenhart on Instagram with your biggest owner-shift takeaway from this episode. If this hit home, share it with a builder who's still stuck in operator mode.Resources:Million Dollar Flip FlopsFollow Us on Insta Ready to transform your business and your life while making a difference? Grab your copy of *Million Dollar Flip Flops*—the ultimate guide to creating a life and business that feels just as good as it looks. And here's the best part: 100% of the proceeds go directly to our foundation, Send a Student Leader Abroad, with a goal of sending 1,000,000 deserving kids on life-changing trips around the world.As a thank you for your support, we're offering exclusive bonuses available only for our podcast listeners. These bonuses are packed with extra tools and resources to help you implement the principles from the book faster and more effectively.Don't miss this opportunity to gain invaluable insights, impact a young leader's life, and be a part of something bigger. Click the link, order your copy, and claim your listener-only bonuses today! Together, let's change lives—one trip at a time.www.MillionDollarFlipFlops.com/book**P.S.** Every book you buy gets us one step closer to sending 1,000,000 kids on life-changing adventures. Let's make it happen!

Finding an analytical CRO that's truly invested in your success, not just processing samples, makes all the difference in CMC development. In this episode, host David Brühlmann talks with Daniel Galbraith, Chief Scientific Officer at Solvias, about the essential questions and mindset that lead to breakthrough CRO partnerships.With nearly three decades in analytical development, spanning monoclonal antibodies, biosimilars, and cell and gene therapies, Daniel reveals what separates CROs who become true partners from those who just run methods. His insights can save your program months of delays and costly missteps.Key Topics Discussed:Why cell and gene therapies face unique challenges compared to the progression seen with monoclonal antibodies (03:04)Daniel's career path: from entering biotech in 1996 to CSO at Solvias, and the rapid evolution of the industry (05:00)The analytical hurdles in characterizing cell-based products and how their inherent variability impacts development (09:46)Approaches to analytical method requirements for autologous cell therapies, and how data is gathered iteratively in these cases (13:02)The biggest obstacles to scaling up cell and gene therapies, and why innovative cell manipulation technologies are needed (16:06)Current trends in therapeutic modalities: why antibody-drug conjugates stand out, and whether mRNA therapies are losing momentum (18:37)Practical advice on choosing an analytical CRO as a strategic partner - what to look for, what questions to ask, and why enthusiasm and standardization matter (21:55)Wondering how to streamline your own analytical strategy, or navigate the parallel universe of cell and gene therapy development? Dig into this episode for Daniel's insider perspective. Then consider how the right analytical partnership could accelerate your path to clinic.Connect with Daniel Galbraith:LinkedIn: www.linkedin.com/in/daniel-galbraith-26a6138Solvias website: www.solvias.comEmail: daniel.galbraith@solvias.comNext step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/callPreparing for your IND? Grab our Startup Founder CMC Dashboard in Notion to help you track tasks, timelines, and risks in one place at https://stan.store/SmartBiotech/p/discovertoind-cmc-dashboard-for-startup-founders

Send us a textWhat if selling your business wasn't the end of your wealth creation journey, but rather the beginning? In this fascinating conversation with Todd Taskey, M&A advisor and host of the Second Byte Podcast, we explore how marketing agency founders can transform a business sale into an extraordinary wealth-building opportunity.Todd reveals the three currencies every business seller receives – cash, earn-out, and equity – and explains why that third component often becomes the most valuable. Through real-world examples like Social SEO (which grew from $2M to $16M in EBIT DA after acquisition) and Endrock Solutions (whose founder went from running a 20-person team to becoming Chief Growth Officer at a 1,700-person powerhouse), Todd illustrates how the "second bite" strategy works in practice.The conversation dives deep into the human elements that make or break these deals. We explore how personality fit between sellers and buyers determines long-term success, why private equity firms in the agency space focus on growth rather than cost-cutting, and the art of structuring earn-outs that actually motivate founders post-acquisition. Todd shares his counterintuitive advice for presenting conservative growth projections during sale negotiations to ensure achievable earn-outs later.We also tackle how AI and automation are reshaping the value equation for professional service firms. Rather than threatening agency values, these technologies may actually increase profitability by enabling firms to serve more clients with fewer people. Todd offers practical wisdom on why agency owners should focus on employee and client retention metrics as the true indicators of business quality, and how to distinguish between building a lifestyle business versus building to sell.Whether you're years away from an exit or actively considering one, this episode provides invaluable insights into maximizing the value of what you've built while creating alignment between your personal goals and your business strategy. The path to extraordinary wealth might just involve taking a smaller slice of a much bigger pie.Prof. Joe O'Mahoney helps boutique consultancies scale and exit. Joe's research, writing, speaking and insights can be found at www.joeomahoney.com

Friday, October 31st, 2025Today, a Tennessee man was held in jail for over a month on a $2M bond because he posted a meme; a Trump nominee for the US export bank withdraws over ties to Russia; Trump lifts sanctions on a Putin-backed autocrat; the administration announces it will resume testing of nuclear weapons; Senate Democrats broaden their investigation into Trump's Epstein ballroom as demolition contractors go underground; four Republicans join Democrats to end Trump's tariffs against Canada; a three star general has been pushed out after conflicts with Hegseth; remembering transgender athlete and student Lia Smith, who took her life at just 21 years of age; and Allison and Dana delivers your Good News.Thank You, HomeChefFor a limited time, get  50% off and free shipping for your first box PLUS free dessert for life!  HomeChef.com/DAILYBEANS.  Must be an active subscriber to receive free dessert.Guest: John FugelsangTell Me Everything - John Fugelsang, The John Fugelsang Podcast, John Fugelsang - Substack, @johnfugelsang.bsky.social - Bluesky, @JohnFugelsang -TwitterSeparation of Church and Hate by John Fugelsang - OUT NOW!Upcoming Live Dates - Separation of Church & Hate book tour NOV 12 - Union StageThe Martin Sheen Podcast - MSW MediaDana Goldberg Outrageous Tour - November 14th ChicagoStoriesTrump nominee at U.S. export bank withdraws amid scrutiny of Russia ties | The Washington Post4 Senate Republicans rebuke Trump for a third time this week, voting with Democrats against president's global tariffs | CNN PoliticsSanctions Lifted on a Putin-Backed Autocrat After Lobbying by Trump Allies | The New York TimesExclusive: Three-star general pushed out amid tensions with Hegseth | CNN PoliticsDemocrats ramp up probes into Trump's $300 million White House ballroom | The Washington PostSonya Massey's father expresses anger after ex-deputy convicted on lesser charge in fatal shooting | CBS NewsTennessee sheriff defends jailing liberal activist for posting Trump meme about school shooting | NewsChannel5Every Trans Suicide Is A Murder By Those In Power | Erin In The MorningGive to honor Lia Smith's memory - MiddleburyGood TroubleIn Texas, there is a SUPER important November 4th vote. The problem with Texas is that Republicans are better at voting in smaller elections, like the one coming up.The Democrat in the race is Taylor Rehmet, an Air Force Vet and Union Organizer. This district has been Republican since 1991 and flipping this will help with acts like the recent Texas gerrymandering. Taylor Rehmet For TexasDana's Good Trouble: Albuquerque, NM - APS District 6 vote for Margaret “Warigia” Bowman - https://www.warigiaforaps.com/➡️ Sign up to phone bank in Virginia.**Group Directory - The Visibility Brigade: Resistance is Possible**California! YOU have your prop 50 ballots. Fill them out and return them ASAP.**Yes On Prop 50 | CA Special Election Phone Banks - mobilize.us, Sign up to call voters in California**Vote Yes 836 - Oklahoma**How to Organize a Bearing Witness Standout**Indiana teacher snitch portal - Eyes on Education**Find Your Representative | house.gov, Contacting U.S. SenatorsFrom The Good NewsHeretic Coffee Co.Refuse Fascism50501 Movement, Josh Johnson - YouTubeThe Martin Sheen Podcast - MSW MediaDana Goldberg Outrageous Tour - November 14th ChicagoOur Donation LinksNational Security Counselors - Donate, MSW Media, Blue Wave CA Victory Fund | ActBlue, WhistleblowerAid.org/beansFederal workers - email AG at fedoath@pm.me and let me know what you're going to do, or just vent. I'm always here to listen. Find Upcoming Actions 50501 Movement, No Kings.org, Indivisible.orgDr. Allison Gill - Substack, BlueSky , TikTok, IG, TwitterDana Goldberg - The 2025 Out100, BlueSky, Twitter, IG, facebook, danagoldberg.comMore from MSW Media - Shows - MSW Media, Cleanup On Aisle 45 pod, The Breakdown | SubstackReminder - you can see the pod pics if you become a Patron. The good news pics are at the bottom of the show notes of each Patreon episode! That's just one of the perks of subscribing!  patreon.com/muellershewrote Our Donation LinksNational Security Counselors - DonateMSW Media, Blue Wave California Victory Fund | ActBlueWhistleblowerAid.org/beansFederal workers - feel free to email AG at fedoath@pm.me and let me know what you're going to do, or just vent. I'm always here to listen. Find Upcoming Actions 50501 Movement, No Kings.org, Indivisible.orgDr. Allison Gill - Substack, BlueSky , TikTok, IG, TwitterDana Goldberg - BlueSky, Twitter, IG, facebook, danagoldberg.comCheck out more from MSW Media - Shows - MSW Media, Cleanup On Aisle 45 pod, The Breakdown | SubstackShare your Good News or Good TroubleMSW Good News and Good TroubleHave some good news; a confession; or a correction to share?Good News & Confessions - The Daily Beanshttps://www.dailybeanspod.com/confessional/ Listener Survey:http://survey.podtrac.com/start-survey.aspx?pubid=BffJOlI7qQcF&ver=shortFollow the Podcast on Apple:The Daily Beans on Apple PodcastsWant to support the show and get it ad-free and early?The Daily Beans | SupercastThe Daily Beans & Mueller, She Wrote | PatreonThe Daily Beans | Apple Podcasts Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

Dr. Maria Sophocles is as a board-certified gynecologist, sex therapist, leading menopause expert, and a popular TED talk speaker. She has taught clinicians this technology on five continents. Her Princeton clinic and virtual practice serves 30,000 women in the US and globally. Dr. Sophocles is currently working on a documentary about sex and menopause and developing a health clinic in rural Kenya. In this episode, Dr. Sophocles discusses the lack of conversation around women's sexual health, and provides insightful information on hormone replacement therapy around menopause. RESOURCES: Learn more about Dr. Sophocles here: https://mariasophoclesmd.com Her viral TED talk with 1.2M+ views: https://www.ted.com/talks/maria_sophocles_what_happens_to_sex_in_midlife_a_look_at_the_bedroom_gap?language=en Instagram: @mariasophoclesmd Pre-order her book The Bedroom Gap on Amazon here: https://amzn.to/48X1XYk Get 15% off Peluva minimalist shoe with coupon code COACHTARA here: http://peluva.com/coachtara CHAPTERS: 0:00 Intro 5:21 Lack of attention in the area of vaginal health 9:52 Shame around sex 11:20 When estrogen goes away 16:40 Systemic HRT 18:00 Bioidentical hormones 21:35 Blood work & pellets 26:00 Dr Sophocles' approach to estrogen & progesterone decline 31:40 What women on HRT can experience 35:20 Separate vaginal and systemic estrogen for cancer patients 37:20 Libido and estrogen, testosterone 40:25 Brain in perimenopause 44:42 Where to learn more from Dr. Maria Sophocles 46:01 "The Bedroom Gap" Book WORK WITH TARA: Are You Looking for Help on Your Wellness Journey? Here's how Tara can help you: TRY COACH TARA APP FOR FREE: http://taragarrison.com/app LEVEL UP PROGRAM: http://taragarrison.com/level-up INDIVIDUAL ONLINE COACHING: https://www.taragarrison.com/work-with-me CHECK OUT HIGHER RETREATS: https://www.taragarrison.com/retreats SOCIAL MEDIA: Instagram @coachtaragarrison TikTok @coachtaragarrison Facebook @coachtaragarrison Pinterest @coachtaragarrison INSIDE OUT HEALTH PODCAST SPECIAL OFFERS: ☑️ Upgraded Formulas Hair Test Kit Special Offer: https://bit.ly/3YdMn4Z ☑️ Upgraded Formulas - Get 15% OFF Everything with Coupon Code INSIDEOUT15: https://upgradedformulas.com/INSIDEOUT15 ☑️ Rep Provisions: Vote for the future of food with your dollar! And enjoy a 15% discount while you're at it with Coupon Code COACHTARA: https://bit.ly/3dD4ZSv If you loved this episode, please leave a review! Here's how to do it on Apple Podcasts: Go to Inside Out Health Podcast page: https://podcasts.apple.com/us/podcast/inside-out-health-with-coach-tara-garrison/id1468368093 Scroll down to the 'Ratings & Reviews' section. Tap 'Write a Review' (you may be prompted to log in with your Apple ID). Thank you!

Michael Assraf is building Flamingo, an open-source and AI-powered operating system for managed service providers. After exiting Vicarious in May 2024, he spent seven months on market research before writing a single line of code—conducting 15+ MSP interviews, mapping their complete tool stack economics, and testing distribution channels with a free community product. The research revealed a structural margin crisis: MSPs operate on 10-15% margins with 30% of revenue flowing to vendor payouts and 25-30% to technician labor. Meanwhile, private equity consolidation drives customer pricing down while legacy vendors raise prices. Michael closed a $2.2 million pre-seed in February 2025, built OpenMSP as a lead-gen vehicle that generated 1,000+ waitlist signups, and launched Open Frame with 70% of capital still in the bank. In this launch-day conversation, he breaks down why the $380 billion MSP market remains massively underinvested, how Facebook ads outperformed LinkedIn 5:1, and why he's giving away the core product while charging for hosted deployment. Topics Discussed: The seven-month research phase: 15+ MSP interviews, mapping 19 tool categories with pricing data, evaluating open source project maturity through commit frequency and VC backing MSP margin compression mechanics: 30% vendor payouts, 25-30% labor costs, 10-15% net margins being crushed by PE-driven consolidation and vendor price increases Building OpenMSP as distribution validation: four months before alpha, generated 1,000 waitlist signups and 200 Slack members while testing paid acquisition channels Why Facebook delivered 40%+ of leads at $6-8 CPL while outbound completely failed with IT-busy MSPs aged 25-50 in central US markets Launching with 70% of $2.2M pre-seed still in bank by solving for distribution and product-market fit before scaling headcount Open Frame's architecture: unified control plane over open source tools (RMM, SSO, zero trust) with dual AI agents—one for end users, one for technicians Offering both self-hosted (free, GitHub) and commercial SaaS (per-seat pricing starting January 2026) to build trust in an underserved market The MSP category opportunity: $380B market, 12% annual growth, 30-40K US MSPs, minimal VC-backed innovation against 20-year-old incumbents GTM Lessons For B2B Founders: Build lead-gen infrastructure before you have a product to sell: Four months before launching Open Frame, Michael shipped OpenMSP—a free tool that analyzes MSP tech stacks and suggests open source replacements. It wasn't a waitlist landing page; it delivered standalone value while capturing intent data. This generated 1,000 qualified signups and 200 Slack community members while simultaneously validating paid acquisition channels. By launch, he knew Facebook cost $6-8 per lead while outbound failed completely. Most founders build product first, then scramble for distribution. Michael inverted the sequence. Fire fast on sales hires in early stage, or don't hire them at all: Michael fired three VP Sales at Vicarious before learning the lesson: "The moment to bring salespeople is not when you are able to sell your product, is when someone else is able to sell your product." The critical test isn't whether the founder can close deals—founders sell vision and relationship. The test is whether a marketing person, SDR, or non-sales hire can generate revenue. Only then do salespeople accelerate an already-working motion. Hiring VP Sales at $50K ARR because the board wants "someone to own revenue" burns 12+ months and $200K+ learning this. Spend 6-12 months researching before building in unfamiliar markets: Michael conducted 15+ MSP interviews, mapped all 19 tool categories they use with pricing, evaluated open source alternatives by analyzing GitHub commit frequency and pull requests, identified which projects had VC backing for long-term viability, and tested multiple marketing channels before alpha deployment. This allowed him to launch with product-market fit indicators already validated and 70% of his $2.2M still in the bank. The alternative—build fast, iterate with customers—works when you deeply understand the market. When you don't, research is cheaper than pivots. Target categories where lack of innovation creates adoption momentum: MSPs represent 30-40K companies in the US alone, part of a $380B global market growing 12% annually. Yet VCs historically avoided the space assuming low ACV and high churn. The dominant platforms—ConnectWise, Datto, Asea—have existed 20+ years with minimal AI adoption or architectural modernization. Michael specifically chose MSPs because "in cyber security you would never get traction that we're getting right now unless you're spending millions of dollars." In crowded categories, distribution cost kills you. In starved categories, any credible innovation gets attention. Architect your product so adoption mechanically improves customer unit economics: Open Frame attacks both sides of MSP margin compression simultaneously. The open source tool suite eliminates the 30% of revenue paid to commercial vendors. The dual AI agent system (end-user self-service + technician orchestration) reduces the 25-30% spent on labor. Michael didn't find a problem and then figure out monetization—he reverse-engineered a solution where product adoption directly expands customer margins. When your product makes customers structurally more profitable, adoption isn't a marketing problem. // Sponsors: Front Lines — We help B2B tech companies launch, manage, and grow podcasts that drive demand, awareness, and thought leadership. www.FrontLines.io The Global Talent Co. — We help tech startups find, vet, hire, pay, and retain amazing marketing talent that costs 50-70% less than the US & Europe. www.GlobalTalent.co   //   Don't Miss: New Podcast Series — How I Hire Senior GTM leaders share the tactical hiring frameworks they use to build winning revenue teams. Hosted by Andy Mowat, who scaled 4 unicorns from $10M to $100M+ ARR and launched Whispered to help executives find their next role. Subscribe here: https://open.spotify.com/show/53yCHlPfLSMFimtv0riPyM

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In this episode, I sit down with Jay Singh, founder of Casper Studios, to explore how AI voice agents are transforming how we create, communicate, and collect information.We dive into how Jay helped Kit's team automate workflows with voice-based AI, why voice will soon replace typing entirely, and how creators can use tools like Whisper Flow and 11 Labs to turn ideas into finished content faster. Jay also gives a live demo, showing exactly how to build a working AI voice agent from scratch.Timestamps:00:00 Introduction01:10 Hitting a $2M run rate with AI implementation03:34 How Kit's team uses AI to build internal tools05:11 Building an automation culture with AI education06:48 Why voice will replace typing09:21 The Apple example and how voice got good again12:16 Why speaking first creates more authentic content18:52 The power of transcripts as creative building blocks22:06 Using voice to collect team insights and automate discovery26:22 Live demo: building a working AI voice agent33:02 Setting guardrails and testing your AI agent40:24 How creators can integrate voice feedback loops47:48 How AI changes human interaction and trust50:01 Practical next steps for creators using voice54:15 Final takeaways and what's next for Casper StudiosIf you enjoyed this episode, please like and subscribe, share it with your friends, and leave a review. I read every single one.Learn more about the podcast: https://nathanbarry.com/showFollow Nathan:Instagram: https://www.instagram.com/nathanbarryLinkedIn: https://www.linkedin.com/in/nathanbarryX: https://twitter.com/nathanbarryYouTube: https://www.youtube.com/@thenathanbarryshowWebsite: https://nathanbarry.comFollow Jay:LinkedIn: https://www.linkedin.com/in/jaysingh10125X: https://x.com/JSingh_08Website: https://casperstudios.xyzFeatured in this episode:Casper Studios: https://casperstudios.xyzKit: https://www.kit.comEleven Labs: https://elevenlabs.ioWispr Flow: https://wisprflow.ai

What if the answer to battling antibiotic-resistant infections isn't a new antibiotic, but harnessing viruses that have been quietly dominating bacterial populations?Bacteriophages, viruses that target and kill bacteria, have been saving lives for a century, but their true potential is only now being unlocked by modern machine learning. The race isn't just about discovering effective phages; it's about deploying the right therapy, personalized to the patient, before time runs out.On this episode, David Brühlmann welcomes José Luis Bila, Co-Founder and CEO of Precise Health. Driven by personal tragedy and an engineer's mindset, José is shaping a future where AI-powered phage therapy isn't a niche solution, but a scalable, accessible weapon against the superbugs that evade antibiotics. From building bioreactor capacity to navigating regulatory gray zones, José brings a rare blend of technical vision and practical urgency to a problem that affects families and health systems worldwide.Key topics discussed:The challenge of evolving bacteria and phages, and the question of whether it's possible to keep up with nature's pace through engineering new phages in silico (00:00)Overview of bacteriophage production: complexity, types of bioreactors used, and comparison with chemical synthesis (02:54)Bioproduction logistics: using CDMOs vs. in-house hospital production and the real-world timescales for manufacturing (02:32)Barriers for smaller or less funded hospitals, especially in low- and middle-income countries, with thoughts on hospital infrastructure differences worldwide (04:41)Creative solutions for cost-effective phage production in remote and underserved regions, such as the potential for single-use or mobile bioreactors (06:01)Why downstream processing and ensuring product purity is a bottleneck; the need for miniaturization and economic scalability (06:40)Parallels and differences in downstream processing between bacteriophages and viral vectors (09:15)The vital role of stability and shelf life for phage therapy logistics and economic viability (09:15)Regulatory pathways for phage therapy in Europe and beyond, including magistral preparations, ethical approvals, and adapting to digital tools for selection (12:39)The future vision: routine clinic entry through matching existing phage libraries, with longer-term goals of engineering bespoke phages via AI when necessary (15:52)José's perspective on building global infrastructure and making phage therapy cost-effective and universally accessible (18:08)José Bila's message: solutions to antimicrobial resistance are within reach. The biotech community must build accessible infrastructure, using AI and innovative systems to ensure phage therapy benefits reach every patient, everywhere.Connect with José Luis Bila:LinkedIn: www.linkedin.com/in/josé-luis-bila-phd-3b08a5a7Precise Health SA: www.precisehealth.ioInterested in how scientists are fighting superbugs? Learn how phage therapy and smart bioprocess design are helping outmaneuver drug-resistant pathogens. Check out this interview with one of our previous guests!Episodes 187-188: From Biology Is Messy to Designable: The Smart Bioprocessing Transformation with Carmen Jungo RhêmeNext step:Book a 20-minute call to help yo

What happens when someone who awarded over $500 million in government contracts from the inside decides to walk away from a secure, six-figure job — all to help people who look like him win from the outside? You get Malcolm Ali, aka Mr. Purchase Order — a powerful force in the world of procurement, government contracting, and economic empowerment. In this episode, Malcolm shares: Why he left a high-paying role in government How he's helped his clients win over $6 million in contracts in just the last 12 months The game-changing $2.2M contract that saved a business Strategies business owners can use today to start winning government deals What it really takes to navigate (and win in) the federal contracting space If you're a small business owner, entrepreneur, or someone passionate about creating generational wealth through public-sector opportunities — this episode is a must-listen.

What do a $1.50 hot dog, a 40-cent ice cream cone, and a business book have in common?They're all deliberately underpriced. And they're also multi-million, and in some cases, billion-dollar growth machines.In this episode, I unpack the sneaky-smart psychology behind the loss leader strategy and why it's one of the most profitable things you can do in your business (even if you're B2B, high-end, or allergic to hot dogs).GET MORE MARKETING & SALES TOOLS:Are you interested in becoming the published author of a powerful book to help you attract more ideal clients and set you apart from the competition? Imagine holding your own book in your hands as quickly as 3-6 weeks without you ever having to write a word. We do all the work, you get all the glory! Find out how we Capture Your Genius at our sister publishing house Lunch Break Books - powerful books for entrepreneurs with big growth goals.Are you subscribed to Marketing Gold? Get more marketing tools, tips and strategies delivered to your inbox most Mondays. Sign up here.Is your business doing $2M+ and you're ready to take it to the next level? We'll show you how. Get your free marketing roadmap by taking the Client Stampede Assessment. It's fast, free (Value $197) and your 20+ page report is emailed to you instantly.Enjoying the podcast? You'll love the audio book. Get The Client Stampede audio book on Amazon.

Ricky Burns: How to build £1M profit in year one (after losing it all at 26)Ricky Burns made incredible money at 26.Then he drank it all away.Partied it into oblivion. Got hit with a massive VAT bill he couldn't pay. Shut the whole thing down.Most people never recover from that kind of failure.Ricky went back into employment for 10 years.Ran European divisions. Watched. Learned. Took notes on what actually works.At 33, he started again.September 2024: Pulse Group launched with his co-founder Tony.12 months later:£1.2M in fees£1M in EBITDA (profit)I don't know anyone who's achieved these numbers in year one.This week on The RAG Podcast, Ricky breaks it all down.We cover:How they hit £1M profit in 12 months (it's simpler than you think)What killed his first business (beyond the partying)The 10 years of lessons that made the comeback inevitableWhy he paired recruitment with SOW consultancyThe systems and client focus driving 83% marginsHow AI is making them more efficient without adding headcountWhy work-life balance is now non-negotiableThis isn't your typical "I scaled fast" story.This is brutal honesty about failure, sobriety, and building something sustainable the second time around.If you've ever wondered what separates 6-figure founders from 7-figure founders - or if you think you've already missed your shot - this episode has the answers.__________________________________________Episode Sponsor: AtlasAdmin is a massive waste of time. That's why there's Atlas, the AI-first recruitment platform built for modern agencies.It doesn't only track CVs and calls. It remembers everything. Every email, every interview, every conversation. Instantly searchable, always available. And now, it's entering a whole new era.With Atlas 2.0, you can ask anything and it delivers. With Magic Search, you speak and it listens. It finds the right candidates using real conversations, not simply look for keywords.Atlas 2.0 also makes business development easier than ever. With Opportunities, you can track, manage and grow client relationships, powered by generative AI and built right into your workflow.Need insights? Custom dashboards give you total visibility over your pipeline. And that's not theory. Atlas customers have reported up to 41% EBITDA growth and an 85% increase in monthly billings after adopting the platform.No admin. No silos. No lost info. Nothing but faster shortlists, better hires and more time to focus on what actually drives revenue.Atlas is your personal AI partner for modern recruiting.Don't miss the future of recruitment. Get started with Atlas today and unlock your exclusive RAG listener offer at https://recruitwithatlas.com/therag/__________________________________________Episode Sponsor: HoxoEvery recruitment founder is investing in LinkedIn.Spending thousands on Recruiter licences.Building connections. Posting content. Growing networks.But here's the question almost no one can answer:How much revenue is LinkedIn actually bringing into your business?Most founders have thousands of connections but no clear process to turn that attention into cash.That's the problem we solve.At Hoxo, we help recruitment founders build predictable revenue systems on LinkedIn, not just noise or vanity metrics.Our clients are turning LinkedIn into £100K–£300K in new billings within months, using their existing...

Join Ash Penley, CEO of ZOEX Power, in conversation with Gary Fowler, as they explore how wave energy is entering a new era of innovation and sustainability. From transitioning out of offshore oil & gas to developing a modular Wave Energy Converter that tackles marine energy's biggest challenge — cost-efficiency — Ash shares her remarkable journey as a solo founder raising £1.2M and building what could become the next unicorn out of ScotlandInsights You'll Learn:✅ The Evolution of Wave Energy – from concept to commercialization✅ Entrepreneurial Grit – how Ash transitioned from oil & gas to renewables✅ Breaking Barriers – being the only woman founder in global wave energy✅ Building a Clean-Tech Startup in Scotland – hurdles, lessons, and wins✅ Future of Marine Power – where innovation and sustainability intersect✅ AI & Energy – how artificial intelligence could accelerate the industry✅ Women in STEM – inspiring the next generation of innovatorsWhy This Matters:*Wave energy is one of the most underutilized renewable resources with immense potential.*ZOEX Power's modular technology could finally make wave power commercially viable.*Ash's journey highlights resilience, innovation, and diversity in clean-tech leadershipExpert Background:• CEO & Founder of ZOEX Power, developer of a modular Wave Energy Converter• 15 years' experience in Offshore Oil & Gas complex installations• Raised **£1.2M** in early-stage funding for marine energy innovation• The only woman founder in Wave Energy globally• Passionate about sustainable innovation and empowering women in STEM

Most people think real estate is all numbers and spreadsheets.Buy low. Sell high. Track your KPIs.That stuff matters. But that's not what keeps your business alive.Dr. Sheri and I break down the actual numbers and edge behind a $2M flipping business.It's how you lead better and survive even when the market takes a dip.Predictable deal flow is a non-negotiable.And there are 2 off-market deal sources many flippers overlook that are COMPLETELY FREE…On November 10th - 13th, I'm going to show you my 6-step system to get 100s of off-market deals sent to your email inbox every week on autopilot for free.I call it the Blackbox Challenge. Because, on a mission, the black box is the one thing that always survives.It records every system, every action, every outcome.That's exactly what I've done for you in the Blackbox Challenge.Join the 4-Day Blackbox Challenge Starting Nov. 10th >>Catch you later!LINKS & RESOURCES1,000 FREE Seller LeadsGet your first 1,000 seller leads FREE from our partner BatchLeads and start closing deals immediately. CLICK HERE: http://leads.getbatch.co/mztQkMr7 Figure Flipping UndergroundIf you want to learn how to make money flipping and wholesaling houses without risking your life savings or "working weekends" forever... this book is for YOU. It'll take you from "complete beginner" to closing your first deal or even your next 10 deals without the bumps and bruises most people pick up along the way. If you've never flipped a house before, you'll find step-by-step instructions on everything you need to know to get started. If you're already flipping or wholesaling houses, you'll find fast-track secrets that will cut years off your learning curve and let you streamline your operations, maximize profit, do MORE deals, and work LESS. CLICK HERE: https://hubs.ly/Q01ggDSh0 7 Figure RunwayFollow a proven 5-step formula to create consistent monthly income flipping and wholesaling houses, then turn your active income into passive cash flow and create a life of freedom. 7 Figure Runway is an intensive, nothing-held-back mentoring group for real estate investors who want to build a "scalable" business and start "stacking" assets to build long-term wealth. Get off-market deal sourcing strategies that work, plus 100% purchase and renovation financing through our built-in funding partners, a community of active investors who will support and encourage you, weekly accountability sessions to keep you on track, 1-on-1 coaching, and more. CLICK HERE: https://hubs.ly/Q01ggDLL0 7 Figure Real Estate Ready RoomUse this proven blueprint to launch and grow your real estate investing business. Step-by-step video course takes you through everything you need to know… and we'll jump on WEEKLY workshops to break down each step with you LIVE! Think of it like getting a master's degree in tactical real estate investing for a fraction of the cost. CLICK HERE: https://7figureflipping.com/ready Connect with us on Facebook and Instagram: @7figureflipping Hosted on Acast. See acast.com/privacy for more information.

Antibiotic resistance isn't just a looming problem. It's a global crisis. Every year, more than one million people die directly from resistant infections, and another 5 million die indirectly. Routine infections are becoming life-threatening, and healthcare systems worldwide are under pressure.Despite decades of warnings, pharmaceutical solutions are falling behind, while “superbugs” continue to outpace new drug development. If trends continue, by 2050, antibiotic resistance could claim 10 million lives annually and cost the world $1 trillion.Meet José Luis Bila, a chemist-turned-biotech-founder, who transformed personal tragedy into a mission to disrupt this deadly status quo. After losing both parents to antibiotic-resistant infections, José dedicated his career to the search for targeted, effective alternatives. Now, as Co-Founder and CEO of Precise Health SA, he's building AI-powered bacteriophage therapy platforms that promise to revolutionize personalized infection treatments and outmaneuver today's most stubborn bacteria.Why tune into this episode? Here are three standouts from José's story and his technical playbook:José's personal story: Losing both parents to antibiotic resistance and its impact on his career path. (00:00)Scope of the antibiotic resistance crisis: Global deaths, indirect impacts, and economic cost projections. (06:29)Why big pharma is pulling out of antibiotic development and why innovation may come from smaller startups. (07:29)Why antibiotic resistance persists: Static nature of antibiotics versus adaptable bacteria, and misuse of antibiotics. (09:45)Introduction to bacteriophage therapy and its specificity challenges. (11:46)The current slow, manual process for matching phages to infections and its limitations in urgent clinical settings. (13:08)How machine learning is being used at Precise Health to rapidly identify and source the right phages using genetic information. (16:58)The potential to reduce phage matching and delivery time from months to just days, and how smart batching and regional surveillance improve economics. (17:23)José Luis Bila's journey shows the power of science driven by purpose. Through persistence, he's pioneering AI-driven phage therapy - offering precision, hope, and a potential lifeline in the fight against antibiotic-resistant infections.Connect with José Luis Bila:LinkedIn: www.linkedin.com/in/josé-luis-bila-phd-3b08a5a7Precise Health SA: www.precisehealth.ioInterested in how scientists are fighting superbugs? Learn how phage therapy and smart bioprocess design are helping outmaneuver drug-resistant pathogens. Check out this interview with one of our previous guests!Episodes 187-188: From Biology Is Messy to Designable: The Smart Bioprocessing Transformation with Carmen Jungo RhêmeNext step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/call

Emily and Kenji grew up with very little and now (at 34 and 36) they've built a $2M net worth and a plan to be work-optional by 40. We pressure-test their CoastFIRE math, reveal why a $1M taxable bridge can still come up short, and show how solo 401(k)s, backdoor Roth conversions, and a small savings re-mix help them reach their goals. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Jump start your journey with our FREE financial resources⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Reach your goals faster with our products⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Take the relationship to the next level: become a client⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Subscribe on YouTube for early access and go beyond the podcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Connect with us on social media for more content⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Bring confidence to your wealth building with simplified strategies from The Money Guy. Learn how to apply financial tactics that go beyond common sense and help you reach your money goals faster. Make your assets do the heavy lifting so you can quit worrying and start living a more fulfilled life. ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠NordVPN.com/MONEYGUY⁠⁠⁠⁠⁠⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

Tom Cock and Apella Wealth advisor Roxy Butner team up for a lively listener Q&A episode covering everything from the new wave of penny-stock IPOs to retirement readiness and tax traps. Tom opens with a warning about the surge in risky penny-stock offerings, then the two dive into listener questions about annuity sales pressure at Fidelity, portfolio diversification mistakes, CD taxation myths, Roth conversions, and one standout 21-year-old listener getting her financial life off to a stellar start. 0:05 Tom opens with a warning about the explosion in penny-stock IPOs 1:26 Why “lottery-ticket” stocks nearly always burn investors 2:21 Diversify, stay tax-efficient, and skip the hype 2:30 Roxy joins for listener Q&A 3:38 Fidelity's annuity pitch — a listener wonders if it's time to leave 5:05 Who's truly fiduciary: Fidelity vs. Vanguard vs. Apella 6:14 Vanguard dipping a toe into crypto 6:51 Quabina from Ohio: $2.2M at 47 — diversified enough to retire at 55? 8:14 Missing global diversification and bonds in an all-U.S. portfolio 9:57 Early-retirement planning challenges and healthcare costs 10:20 How to design the right stock-bond-international mix 11:36 Daniel from California: Are long CDs taxed as capital gains? 13:04 Why CD interest is always ordinary income — and muni bond alternatives 13:29 Year-end planning: RMDs, Roth conversions, and tax optimization 14:45 Common tax mistakes and mis-placed assets 15:19 Emily from Ohio: “Young and Dumb” — a 21-year-old investing the smart way 18:51 Building a first Roth IRA and why bonds don't belong yet 20:00 One-fund simplicity: AVGE vs. VOO 21:41 Long-term mindset: global diversification and patience pay off Learn more about your ad choices. Visit megaphone.fm/adchoices

In this solo episode, Dr. Debi shares 11 anonymized, real-world scenarios showing how unhealed betrayal quietly derails performance, leadership, health, and culture at work. From weight changes and gut issues to micromanagement, perfectionism, disengagement, and self-betrayal, you'll see how a personal rupture (even years old) can surface on the job—and what to do about it. You'll also hear research-backed prevalence stats (weight, gut, sleep) and a clear invitation to move from Stages 2–3 (shock and survival) into Stages 4–5 (healing and growth).    Who this episode is for  Professionals, leaders, and founders who feel “off” at work and can't trace why  HR/people leaders noticing unexplained dips in performance, morale, or collaboration  Anyone who suspects an earlier betrayal might still be shaping today's choices, health, and capacity    Key concepts & signals  Betrayal shows up at work physically (weight, gut, sleep), mentally (focus, overthinking), emotionally (hypervigilance, distrust).  Nervous system hijack: After broken trust, people often swing to micromanagement, second-guessing, isolation, or over-preparation.  Stages matter: Creativity, confidence, and connection typically reliably return as you move into Stages 4–5 of the 5-Stage model.  Research snapshots (from Debi's community data):  Weight/eating struggles: ~47%  Gut issues (IBS/Crohn's/constipation/diarrhea): ~45%  Sleep problems: ~68%    Case snapshots (anonymized)  Sarah — Weight & confidence spiral Discovery of husband + best friend affair → stress eating → +40 lbs, pre-diabetes, energy crash. Missed two promotions; client-facing confidence plummeted.  Marcus — Gut & career derailment Brother's $50k “investment” betrayal (borrowed from 401k) → nausea → IBS, 30 missed days in 6 months, $12k out-of-pocket care → transfer to lower-paying support role.  Jennifer — From empowering to micromanaging Daughter's addiction/deceit eroded trust → hypervigilance, excessive approvals, morale drop → $30k demotion.  David — Cultural catalyst to clock-watcher Father covertly rewrote will for estranged sister → emotional numbness → stopped mentoring/initiatives → ~25% drop in departmental satisfaction.  Lisa — Anxiety, over-prep, stalled growth Fiancé + maid of honor affair weeks before wedding → panic in meetings, medical leave, therapy costs → over-preparation and hesitation → lost Senior Manager promotion.  Tom — Creativity collapse Close friend's emotional affair with his partner during family caregiving → withdrew creative risk-taking → lost edge in pitches → 3 major accounts (~$2M) missed.  Rachel — Sleepless CEO Sister's manipulation of elderly mother & finances → insomnia, ruminations → poorer board-level decisions, investor strain, performance dip; sleep meds added side-effects.  Kevin — Isolation after double betrayal Wife left for best friend → withdrew from people, closed-door leadership → cross-functional effectiveness down ~40%; silos and delays multiplied.  Maria — Paralysis by over-analysis Business + romantic partner embezzled to fund secret life → hyper-checking, documentation glut → missed time-sensitive opportunities; costly lost trading advantage.  Robert — Purpose lost, pipeline thins Adult son (aided by brother) sued him for “emotional damages” → quit mentoring/junior development → leadership pipeline weakened; burnout → early retirement.  Andrea (self-betrayal) — Successful but misaligned Pressured away from teaching into law → chronic fatigue, migraines, disengagement, ~30% billable drop, ~$800k lost potential revenue → leave of absence. The cost wasn't only professional—it was existential.    How to spot it (self-check)  “I don't recognize how I lead or work anymore.” (micromanaging, over-prepping, perfectionism)  “My body is louder than my calendar.” (gut flares, migraines, insomnia before big decisions)  “I'm here but not really here.” (numbness, disengagement, loss of initiative/mentoring)  “I don't trust my read on people.” (multiple confirmations for simple tasks, second-guessing)  “I'm productive—but always late.” (hyper-vigilant thoroughness that kills timeliness)  “I'm successful—and empty.” (self-betrayal: achievement without meaning)    Try this: 6 reflection prompts  Which case felt uncomfortably familiar—and why?  Where does betrayal show up most for you: body, mind, or relationships at work?  What do you over-do (control, analyze, isolate) to feel safer—and what does it cost?  Which responsibility did you stop (mentoring, initiating, pitching) after the rupture?  What would “Stage 4–5 me” do differently this week?  If self-betrayal is the theme, what small act of alignment could you take in 72 hours?    If you lead a team (HR, managers, execs)  Watch for sudden style flips (empowering → micromanaging; creative → conventional).  Replace “performance policing” with support + boundaries (clear priorities, fewer approvals, flexible micro-rest).  Offer psychological safety + access to evidence-based healing resources; normalize PTO for real recovery.  Protect culture carriers (your “Davids”)—and rebuild when they dim.    Practical next steps  Name it: If you recognized yourself, that's progress.  Assess: Take the Post Betrayal Syndrome® indicators seriously (weight, gut, sleep).  Stabilize the body: Basic routines (sleep hygiene, hydration, movement) reduce reactivity.  Skill up: Learn boundaries, rebuild self-trust, and pace decisions during healing.  Advance stages: If you're in Stages 2–3, get guided support to move into 4–5, where creativity, confidence, and connection reliably return.  Share back: Tell Dr. Debi which story resonated most; it helps tailor future episodes.  Memorable lines  “We can try to leave betrayal at the door—but our body and leadership bring it to work.”  “Micromanagement is often a trust injury in disguise.”  “Success that betrays you is still betrayal.”  Resources & links  The PBT Institute — programs, coaches, community: https://thepbtinstitute.com/  Corporate/HR offerings & talks: https://thepbtinstitute.com/corporate/  Tell Dr. Debi which scenario hit home for you, and what you'll try this week. See you next time. 

Episode 401 of The VentureFizz Podcast features Nicole Phillips-Bastian of Qatch. This episode was recorded live at Startup Boston Week at Suffolk University which is the third year that I've hosted it onsite. Thank you to Stephanie Roulic for the invitation, as it's a lot of fun and great to be involved in such a meaningful conference. And, since it was hosted live, this episode is audio only and my apologies for the background noise. Personalization isn't a new term in the world of tech but as a consumer, it often fails. It could be a failure around the data, the actual tech powering the experience, or executional challenges. For Qatch (which stands for Quick Match), they have been able to overcome these challenges by establishing trust with consumers in one of the most coveted spots for obtaining first party data… no, it's definitely not email, but through text messaging. Qatch is a personalized shopping platform that allows user preferences to dictate what products they see next. Their platform enables the company to capture user engagement to a degree other brands are not, which gives them incredibly valuable insight into what products a specific shopper would buy, so they can recommend it to them in real-time. It all falls under that trust factor which is so important, because if Qatch is not delivering value, it's easy to block that text message and it is this level of trust that has been so key to their success. Two interesting points to note: 1. Nicole's co-founder for Qatch is her sister Raquel. 2. They have built a very capital efficient company, as they have raised just under $2M in funding. In this interview, we cover: * The importance of founder-led sales. * Nicole's background story and her journey into law as a retail attorney with a focus on fashion law and regulations. * All the details about Qatch and why they decided on text messaging as their primary method of communication. * How the platform works and their use of AI. * Sales and getting brands to join their platform, plus how they evolved their pricing strategy. * The competition and how they differ from companies like Stitch Fix. * Her experience raising capital as a female founder and why sales is the best form of funding. * And so much more.

When I sat down with Ed Bray, VP of Growth at Orama, he told me why cutting 60% of his clients was the best decision he ever made.In this episode, we unpack how that bold move transformed Orama's US business from chaos to clarity, scaling to $2M with a leaner client base, a stronger delivery engine, and a “fewer, better” mindset.We also dive into Ed's journey from average biller to operator, his obsession with BD excellence, and what every recruiter can learn from his US playbook.You can connect with Ed here: https://www.linkedin.com/in/edward-bray-86070b142/-------------------------Watch the episode on YouTube: https://youtu.be/G5fu358_IMI-------------------------Sponsors - Claim your exclusive savings from our partners with the links below:CapEx Currency - Check Out CapEx & Claim Your Exclusive Offer HereSourcewhale - Check Out Sourcewhale & Claim Your Exclusive Offer Here.Raise - Check Out Raise & Claim Your Exclusive Offer Here.-------------------------Extra Stuff:Learn more about our online skills development platform Hector here: https://bit.ly/47hsaxeJoin 6,000+ other recruiters levelling up their skills with our Limitless Learning Newsletter here: https://limitless-learning.thisishector.com/subscribe-------------------------Get in touch:Linkedin: https://www.linkedin.com/in/hishemazzouz/-------------------------

Confident Security, a technology enabling provably private AI interactions, announced its public launch with $4.2M in funding. In this episode, CEO Jonathan Mortensen joins host Scott Schober to discuss the funding, the company's mission, and more. • For more on cybersecurity, visit us at https://cybersecurityventures.com.

Too many smart, capable women stay stuck in roles that feel “safe.” In this episode, Kendall Berg and Dr. Candace Steele Flippin unpack why — and how to finally break free. Drawing on groundbreaking research from her book and her SHAPE Framework (Safe, Hard Work, Advocate, Persevere, Educate), Dr. Candace reveals the hidden connection between financial stability and career confidence — and why money literacy isn't just about saving, it's about power. Together, they explore how self-advocacy, financial readiness, and strategic visibility help women move from fear to freedom. Whether you're hesitating to take a promotion, negotiate your worth, or leave a role that no longer fits, this conversation gives you the mindset and tools to stop playing it safe and start shaping your next chapter.

Sports Cards Live episode 287, Part 1. Jeremy sits down with Joe Poirot to kick off the night, then Leighton Sheldon jumps in for a deep dive on the headline sale of the 1914 Baltimore News Babe Ruth that just hammered around 4M after a prior 7.2M comp. We unpack why rare does not always equal iconic, how schedule issues compare to Goudey Ruths, and what “value” means when a card trades so infrequently. From there we zoom out to the auction landscape: shill bidding realities, house bidding on behalf of consignors, and reserves—how they work, where they are disclosed, and how buyers can protect themselves. Jeremy shares a Classic Auctions mail day, completing a 1952 Parkhurst “flight” with Rocket Richard alongside Gordie Howe, Terry Sawchuk, and Tim Horton, plus a fun pickup of game-used Mats Sundin gloves. We also touch on Probstein moving off eBay to SNYPE, Fanatics vault strategies, and using Card Ladder to sanity-check comps. What you'll learn Why the Baltimore News Ruth can lag iconic appeal despite extreme rarity How auction house reserves and house bids can affect bidding behavior Practical tactics to limit shill exposure set a ceiling price and stick to it How “flight collecting” works as a middle path between set and type collecting Vintage hockey targets in 1951–52 Parkhurst and why they resonate Learn more about your ad choices. Visit megaphone.fm/adchoices

Your process works perfectly at two-liter bench scale. Then you hit fifty liters and titer drops 20%. By two hundred liters, aggregation appears and charge variants shift. Your management team asks: "How long to fix this?" The honest answer? Three to twelve month, because you're flying blind.In Part 2 of this Quality by Design Master Class, David Brühlmann reveals why scale-up chaos isn't inevitable. It's a solvable engineering problem. Drawing on experience leading bioprocess innovation at Merck and guiding biotech companies through CMC development, David delivers the process control framework that transforms reactive troubleshooting into predictive manufacturing.The core truth: eighty percent of quality problems stem from twenty percent of your process variables. David shows how to identify Critical Process Parameters, implement intelligent control strategies, and leverage hybrid modeling that reduces experiments by 60-80%. With case studies from Genentech and Amgen, you'll gain the blueprint that turns QbD requirements into competitive advantage.Part 1 taught you what to build and measure. Part 2 shows you how to control your process to consistently deliver commercial-scale quality.Topics Discussed:The common pitfalls of scaling up manufacturing from bench to production, and why process control must go beyond end-product testing (02:10)Overview of the QbD framework: Quality Target Product Profile (QTPP), Critical Quality Attributes (CQAs), and the focus of this episode - Control Strategies for manufacturing (05:00)Identifying and monitoring Critical Process Parameters (CPPs) and their impact on quality, with real-world examples from Genentech's monoclonal antibody platform (08:20)Structure of an effective manufacturing control strategy: Input, process, and output controls - including practical details on real-time monitoring and release testing (11:00)The role of hybrid modeling and machine learning in accelerating process optimization, and how this approach can dramatically reduce the experimental burden (13:30)Real examples of improved outcomes and efficiency through model-based control strategies, and why training and process understanding are essential for team success (16:10)A quick, actionable exercise biotech teams can use to map process risks and identify critical control points (16:55)Whether you're part of a start-up or a large biotech firm, this episode offers clear, strategic steps for implementing QbD and improving process reliability. Don't forget to listen to Part 1 for more on QTPP and CQA, and visit www.bruehlmann-consulting.com for additional resources.Next step:Book a 20-minute call to help you get started on any questions you may have about bioprocessing analytics: https://bruehlmann-consulting.com/callPreparing for your IND? We're building a CMC Dashboard in Excel to help biotech founders track tasks, timelines, and risks in one place. Join the waitlist for early access at https://scale-your-impact.notion.site/27dd9c6ba679804b80a7ce439d56c91a?pvs=105

Congress refers former CIA director John Brennan for criminal prosecution; Trump seeks a settlement from Biden's Mar-a-Lago raid; Portland Cops are seen protecting the protesters from the feds Watch VINCE Live on Rumble - Mon-Fri 10AM ET ⁠⁠⁠⁠ ⁠⁠https://rumble.com/vince⁠ Trump Said to Demand Justice Dept. Pay Him $230 Million for Past Cases https://www.nytimes.com/2025/10/21/us/politics/trump-justice-department-compensation.html Justice Department reaches $2M in settlements with FBI officials whose texts infuriated Trump https://www.politico.com/news/2024/07/26/peter-strzok-lawsuit-settlement-00171498 Garland defends $700K McCabe settlement https://www.politico.com/news/2021/10/27/garland-mccabe-settlement-517333 Sponsors: Goldbelly - https://Goldbelly.com code: Vince Bon Charge - https://boncharge.com and use code: Vince Stopbox - https://stopboxusa.com code: VinceShow BrickHouse Nutrition - https://takelean.com code: Vince Learn more about your ad choices. Visit podcastchoices.com/adchoices

Gorkem Yurtseven is the co-founder and CEO of fal, the generative media platform powering the next wave of image, video, and audio applications. In less than two years, fal has scaled from $2M to over $100M in ARR, serving over 2 million developers and more than 300 enterprises, including Adobe, Canva, and Shopify. In this conversation, Gorkem shares the inside story of fal's pivot into explosive growth, the technical and cultural philosophies driving its success, and his predictions for the future of AI-generated media. In today's episode, we discuss: How fal pivoted from data infrastructure to generative inference fal's explosive year and how they scaled Why "generative media" is a greenfield new market fal's unique hiring philosophy and lean

SUMMARY: - Guest, Author and speaker Debora Coty shares how to find joy amid pain, drawing from deep personal losses and decades of ministering to women. - Writing journey: Her Too Blessed to Be Stressed brand unexpectedly grew to 40+ books/products with 2M+ copies sold worldwide; new devotional Bless Your Heart focuses on daily encouragement. - “Papa God”: She uses the intimate, biblical sense of Abba (Papa/Daddy) to help women experience God's unconditional love beyond imperfect earthly-father images. - Faith in crisis: Six miscarriages triggered a two-year spiritual shutdown; daily praying through the Psalms—starting with “angry” psalms—slowly reopened her heart to God's presence. - Recent trials: Multiple family deaths, job loss, knee replacements, a spouse's cancer, and a 5-year legal battle to protect her grandchildren—culminating in unexpected, miraculous breakthrough. - Joy vs. happiness: Happiness depends on circumstances; joy is a chosen, steady confidence in God's unchanging character that can coexist with grief. - Tools for resilience: Gratitude (Philippians 4:6–7), worship/music, nature, Scripture, intentional fun and laughter, and noticing daily “grace notes” (small signs of God's care). - “BOGO blessings”: Inspired by 1 Peter 3:9—when you bless others, you “be one, get one,” receiving blessing as you give it. - Anchoring Scriptures: Philippians 4:6–7 (peace covenant), Psalm 46:1 (ever-present help), Psalm 147:3 (heals the brokenhearted). - Invitation: Join her BFF (Blessed Friends Forever) community for mutual prayer, encouragement, and practical faith; final charge—keep seeking God's presence with perseverance.   PODCAST INTRO: If you've ever wondered how joy can possibly coexist with grief, today's conversation is for you. I'm joined by beloved author and encourager Debora Coty—creator of the Too Blessed to Be Stressed series, with over two million copies in print worldwide. She and I had a chance to connect for the podcast while she was visiting family in the Smokey Mountains and Debora brought her signature warmth, humor, and hard-won wisdom to help us find God's presence in life's most painful seasons. We talk about the difference between happiness and true, resilient joy; how scripture—especially the Psalms and Philippians 4:6–7—anchors us when our faith feels shaken; and the “grace notes” God sprinkles through our days when we learn to look for them. Debora opens up about profound losses—miscarriages, family heartbreak, health challenges, and a long, exhausting court battle—and how waiting on God can still lead to breathtaking redemption. You'll hear practical tools to refresh a weary spirit: gratitude that changes the atmosphere, worship that invites God's presence, nature that whispers His care, and yes—laughter—as a catalyst for joy. Debora also shares about her new devotional, Bless Your Heart, and invites you into her BFF—Blessed Friends Forever—community for prayer, connection, and ongoing encouragement. Let's listen in as Debora shares her message of joy, hope and encouragement. As soon as she starts talking you know immediately that's she's an encourager at heart maybe it's because she exudes the joy of the Lord…and because of that joy, I think you'll be surprising to hear all that she's been through and yet she still keeps leaning on Jesus for His joy and strength. Live Loved and Thrive @alifeofthrive.com Sherrie Pilk   ADDITIONAL BLOGS AND/OR PODCASTS ON THIS TOPIC: Joy in the Midst of Grief, with Author Sonya Mack: https://alifeofthrive.com/2023/01/04/joy-in-the-midst-of-grief-with-author-sonya-mack/ Finding Hope in the Ashes, with Lea Turner: https://alifeofthrive.com/2024/09/25/finding-hope-in-the-ashes-with-lea-turner/ Widows, Grief and Finding Hope, with Anne-Marie Lockyer: https://alifeofthrive.com/2024/02/14/widows-grief-and-finding-hope-with-anne-marie-lockmyer/ The Possibility of Joy After Child Loss, with Lisa Espinoza: https://alifeofthrive.com/2025/07/16/the-possibility-of-joy-after-child-loss-with-lisa-espinoza/   CONNECT WITH DEBORA: Website: https://deboracoty.com/ Learn more about Debora's BBF (Blessed Friends Forever) Group by subscribing to her blog (which is on her website)   BIO: Debora M. Coty is an events speaker, columnist, certified writing coach, and award-winning author of over 200 articles and 40 inspirational book products, including the bestselling Too Blessed to be Stressed series, which has influenced two million lives worldwide. An orthopedic occupational therapist for 36 years and piano teacher for 30, Debora rejoices in life as a diehard tennis addict and choco-athlete (that's the step beyond chocoholic – she exercises just so she can eat more chocolate). She's a bodacious women's Bible study leader, and animated storyteller to anyone who'll listen. Deb lives, loves, and laughs in central Florida with her long suffering husband of 47 years, two grown children, and five precocious grandbuddies. Debora, known for her offbeat blend of humor and hope, has a passion for bringing women together to deepen relationships vertically (with their heavenly Father) and horizontally (developing heart-friends). Deb loves hosting a fun-loving community of BFFs (Blessed Friends Forever) from all over the globe at www.DeboraCoty.com.

When life threw Dylan Jahraus a curveball, she didn't fold—she built a 7-figure business instead.From climbing the corporate ladder to becoming a stay-at-home mom, to scaling a multi-million-dollar Etsy shop and pivoting into digital education, Dylan's journey is packed with lessons in resilience, reinvention, and unapologetic growth.

In a world where “charge what you're worth” and “raise your prices” dominate the entrepreneurial conversation, Kelly is flipping the script with a reality check: In this episode, she reveals why some of her biggest business wins — from stage appearances to multi-million-dollar brand growth — came not from getting paid upfront, but from playing the long game. You'll learn when it actually pays to work for free, how to evaluate opportunities strategically, and how to turn short-term sacrifice into long-term expansion. If you've been wondering whether to charge or say “yes” for exposure, relationships, or visibility — this is your playbook for discerning which “free” is actually profitable. Timestamps:  [00:40] – Why “charge what you're worth” isn't always great advice — and how nuance creates better business decisions. [02:00] – The problem with instant gratification and how long-term strategy builds wealth  [04:15] – Free vs. paid speaking engagements — the $20K talk vs. the thousand-person audience. [05:45] – The free, local speaking events that led to new paying clients within 48 hours. [07:00] – The asset advantage: why visibility and brand content are often worth more than upfront payment. [08:30] – Kelly's 4-part checklist for evaluating an unpaid opportunity [10:15] – The truth about big stages: how most speakers land them — and why most aren't getting paid. [13:30] – Why Kelly doesn't take podcast sponsors (yet) and how the show makes millions without a single paid ad slot (and why long-term audience trust is more profitable). [18:00] – The currency of integrity: why doing the right thing compounds in value over time. [19:00] – Final encouragement: trust your discernment, play the long game, and remember — nothing is impossible with God.   Resources: Join The Virtual Business School now for just $87/month, no contract: https://go.virtualbusinessschool.com/joinvbs  Learn more about our Legacy Leaders Mastermind: The premier mastermind for established 7- and 8-figure CEOs: https://programs.thebusinessadvisory.com/legacy-leaders  Join us in person this March for our annual Legacy retreat ($2M+ business owners): https://advancesociety.org/2026rsvp  Follow Kelly on Instagram: https://www.instagram.com/kellyroachofficial/                Follow Kelly on Facebook: https://www.facebook.com/kelly.roach.520/w     Connect with Kelly on LinkedIn: https://www.linkedin.com/in/kellyroachint/