Podcasts about brain research institute

[20250103] Crónicas de San Borondón Arrancamos este viernes 3 de enero nuestro primer Crónicas de San Borondón de 2025, y lo hacemos por todo lo alto, con temas e invitados que aportan claridad y profundidad a los asuntos abordados. El periodista Carmelo Rivero inaugura nuestro año y nos visita para hablarnos, entre otros temas vividos personalmente por él, de la vida y misterios de Jacobo Grinberg. El destacado neurofisiológico mexicano, conocido por sus investigaciones sobre la conciencia, el chamanismo y la parapsicología, desapareció misteriosamente el 8 de diciembre de 1994. Grinberg estudió psicología en la Universidad Nacional Autónoma de México (UNAM) y obtuvo un doctorado en psicofisiología en el Brain Research Institute de Nueva York. Fundó el Instituto Nacional para el Estudio de la Conciencia (INPEC) y publicó más de 50 libros sobre temas como la actividad cerebral, la brujería, el chamanismo, la telepatía y la meditación. Su trabajo con Pachita, la mítica y asombrosa curandera mexicana, es desconcertante. Su desaparición ha generado diversas teorías y especulaciones. Algunos creen que su trabajo en áreas controvertidas como la telepatía y el chamanismo pudo haber jugado un papel en su desaparición. A pesar de los años, su legado sigue siendo relevante y su trabajo continúa siendo estudiado y discutido. Contar con Carmelo Rivero para hablar de todo ello es un lujo. El Catedrático de Arqueología de la Universidad de La Laguna, Antonio Tejera Gaspar, y la Doctora en Filología Clásica por la Universidad de La Laguna, Alicia García García, pasarán por CSB para diseccionar el mito, convertido en realidad geográfica, de las islas Afortunadas, que describe el conocimiento antiguo de Canarias y la posibilidad de que el mismo fuese anterior a lo estimado. Finalmente, el periodista y veterano investigador Miguel Pedrero nos dará algunas de las claves de su más reciente libro, PERO NO LO DIGAS, en el que describe la alucinante historia de una familia de contactados con inteligencias extraterrestres por más de medio siglo.

[20250103] Crónicas de San Borondón Arrancamos este viernes 3 de enero nuestro primer Crónicas de San Borondón de 2025, y lo hacemos por todo lo alto, con temas e invitados que aportan claridad y profundidad a los asuntos abordados. El periodista Carmelo Rivero inaugura nuestro año y nos visita para hablarnos, entre otros temas vividos personalmente por él, de la vida y misterios de Jacobo Grinberg. El destacado neurofisiológico mexicano, conocido por sus investigaciones sobre la conciencia, el chamanismo y la parapsicología, desapareció misteriosamente el 8 de diciembre de 1994. Grinberg estudió psicología en la Universidad Nacional Autónoma de México (UNAM) y obtuvo un doctorado en psicofisiología en el Brain Research Institute de Nueva York. Fundó el Instituto Nacional para el Estudio de la Conciencia (INPEC) y publicó más de 50 libros sobre temas como la actividad cerebral, la brujería, el chamanismo, la telepatía y la meditación. Su trabajo con Pachita, la mítica y asombrosa curandera mexicana, es desconcertante. Su desaparición ha generado diversas teorías y especulaciones. Algunos creen que su trabajo en áreas controvertidas como la telepatía y el chamanismo pudo haber jugado un papel en su desaparición. A pesar de los años, su legado sigue siendo relevante y su trabajo continúa siendo estudiado y discutido. Contar con Carmelo Rivero para hablar de todo ello es un lujo. El Catedrático de Arqueología de la Universidad de La Laguna, Antonio Tejera Gaspar, y la Doctora en Filología Clásica por la Universidad de La Laguna, Alicia García García, pasarán por CSB para diseccionar el mito, convertido en realidad geográfica, de las islas Afortunadas, que describe el conocimiento antiguo de Canarias y la posibilidad de que el mismo fuese anterior a lo estimado. Finalmente, el periodista y veterano investigador Miguel Pedrero nos dará algunas de las claves de su más reciente libro, PERO NO LO DIGAS, en el que describe la alucinante historia de una familia de contactados con inteligencias extraterrestres por más de medio siglo.

In this episode, we discuss Autism with Dr. Leanna Hernandez. Dr. Hernandez is an Assistant Professor in the Department of Psychiatry and Biobehavioral Sciences at UCLA and director of the Hernandez Lab. She is a member of UCLA's Center for Autism Research and Treatment, Center for Neurobehavioral Genetics, and the Brain Research Institute, and serves as Co-Director of the Genetics, Genomics, and Informatics Core for UCLA's Intellectual and Developmental Disabilities Research Center.Hernandez Lab https://www.hernandezlabucla.orgAdditive effects of oxytocin receptor gene polymorphisms on reward circuitry in youth with autism https://www.nature.com/articles/mp2016209Imaging-genetics of sex differences in ASD: distinct effects of OXTR variants on brain connectivity https://www.nature.com/articles/s41398-020-0750-9Oxytocin and Vasopressin and the Autistic Phenotype https://podcasts.apple.com/us/podcast/from-the-spectrum-finding-superpowers-with-autism/id1737499562?i=1000660031273 https://www.youtube.com/watch?v=DAtmC-s1_e0(0:00) Intro; Dr. Leanna Hernandez(2:24) Autistic Phenotypes(4:13) Dr. Hernandez education journey into Autism and the Hernandez Lab(9:03) 2017 Paper Oxytocin Receptor Gene, Common Genetic Variance, Single Nucleotide Polymorphisms (SNP), and Reward and Social Processing and the Nucleus Accumbens (NAc)(15:10) Differences in Brain Connectivity between Autistics and Non-Autistics(20:06) Social Cognition, Boy Bias in Autism; GENDAAR Consortium and Sex- and Diagnosis-Differences(21:48) GENDAAR(22:45) Boys versus Girls Connectivity involving the NAc with and without Autism(25:38) Different Connectivity correlated with Different ADOS scores for Repetitive Behaviors(26:35) Female Protective Effect for Autism; Camouflaging/Masking(30:19) The Assessment process for Girls and the Oxytocin Receptor Gene Sex Differences and Socialness and understanding the Boy Bias(32:48) Current Research and a Genome Wide approach and Polygenic Risk Scores(35:10) Oxytocin and Excitation/Inhibition(37:08) Sharing Information and Current Research(41:45) The Future of Autism Research(45:48) Reviews/Ratings and Contact Infoemail: info.fromthespectrum@gmail.comX: https://twitter.com/rps47586Facebook: https://www.facebook.com/fromthespectrum.podcast

On Thursday, September 8, 2022 we were joined by Genaro Coria-Avila, to talk about sexually dimorphic nuclei in the brain, other forms of brain sexual dimorphism, and their relation to sexual behavior. Guest: Dr. Genaro Coria-Avila, Genaro is a research scientist at the Brain Research Institute at the Universidad Veracruzana in Xalapa, Mexico. Participating: Fidel Santamaria, Department of Neuroscience, Developmental and Regenerative Biology UTSA Daniela Monje, Department of Neuroscience, Developmental and Regenerative Biology UTSA Host: Charles Wilson, Department of Neuroscience, Developmental and Regenerative Biology UTSA

On Thursday, September 8, 2022 we were joined by Genaro Coria-Avila, to talk about sexually dimorphic nuclei in the brain, other forms of brain sexual dimorphism, and their relation to sexual behavior.Guest:Dr. Genaro Coria-Avila, Genaro is a research scientist at the Brain Research Institute at the Universidad Veracruzana in Xalapa, Mexico.Participating:Fidel Santamaria, Department of Neuroscience, Developmental and Regenerative Biology UTSADaniela Monje, Department of Neuroscience, Developmental and Regenerative Biology UTSAHost:Charles Wilson, Department of Neuroscience, Developmental and Regenerative Biology UTSA

[INT] Swiss voters reject ban on animal testing Guest: Professor Sebastian Jessberger, Director, Brain Research Institute, University of ZurichSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Jason and Matthew interview Dr. Barry Komisaruk, Neurophysiologist from the Psychology Department at Rutgers University. Barry has been researching sexuality for over 50 years and is maybe best known for the seminal work: The Science of Orgasm. We talk about the history of his research and discoveries, the historical challenges around sexual function research and ideas for how to further this area of research to benefit folks with SCI. Pay particular attention to the latter half of the podcast if you're interested in participating in a study idea that we landed on collectively. If it piques your interest, send us a message at curecast@u2fp.org and we'll connect you. --- Barry R. Komisaruk received a B.S. in biology at The City University of New York and Ph.D. in psychobiology from Rutgers University. He was a National Institute of Mental Health postdoctoral fellow in neuroendocrinology at the Brain Research Institute, University of California at Los Angeles. Joining the Rutgers-Newark faculty in 1966, Komisaruk was a professor in the Institute of Animal Behavior and Department of Zoology. He is now Distinguished Professor in the Psychology Department, director of the Minority Biomedical Research Support Program, and former associate dean of the Graduate School. With a penchant for finding new research avenues to explore, Komisaruk received a Board of Trustees of Rutgers University Excellence in Research award and the Hugo G. Beigel Research Award of the Society for the Scientific Study of Sexuality. His major research interests include: functional neuroimaging of genital sensory response; neurophysiology, neuropharmacology and neuroendocrinology of reproductive behavior; and neural control of autonomic genital function. He is senior author of The Science of Orgasm, a comprehensive look at the biology and neuroscience of orgasm, published by The Johns Hopkins University Press, as well as The Orgasm Answer Guide, a general readership book from the same publisher. He has published more than 155 academic journal articles and chapters.

Inside the Castle is a small press operated from Lawrence, Kansas by John Trefrey. Their books are unique from one another but share a vision, that literature is not representational but incantatory, that books are objects that exist much like other objects in your life and home, only they have additional dimensions, not dimensions separate or distant from the ones you occupy, but involuted dimensions that only become apparent when you reach out to them. _ Megan Jeanne Gette is an anthropology PhD student and fellow at UT Austin. She has an MFA in poetry from the University of Minnesota. Her research explores the role of the mineral in renewable energy transitions, sensory ethnography, and subterranean/energy imaginaries. She is a section editor for the Visual and New Media Review and co-creator of con-text-ure at Society for Cultural Anthropology's Fieldsights. In Majority Reef, there are 8 SURFACES. Eight surfaces can form an octahedron, which looks like two triangular prisms put together at their bases, which forms the interior of a sphere, such as the globe. Within each section is a lyric essayistic syntax of "recursive loops of longing" or an "infinite palimpsest of pain or desire," a variety of 8 tones--or perhaps a doubling of the 4 humors--that loop in a style I am calling Weeping Lemon Meringue, or echo-poetics, the ant-I- narcissus. _ Germán Sierra got his MD and PhD degrees at the University of Santiago de Compostela (Spain) before doing postdoctoral research in Cognitive Neuroscience at the Brain Research Institute in UCLA. He currently works at the Department of Biochemistry and Molecular Biology of the University of Santiago de Compostela (Spain). As a writer, Germán Sierra is deeply interested in contemporary experimental fiction. He has been included among the “Mutantes” or “Afterpop writers”: a group of Spanish writers who are strongly committed with innovative literature. Most of his fictional work deals with metamediatics and the role of science and technology as cultural discourses in post-postmodern and posthuman societies. In the clever [dis]guise of fiction, what The Artifact in fact foists upon its readers (hoisting us up in so doing so that ultimately we can look down on the whole situation from a higher perspective—albeit only to crash like a bluebird into the window through which we bear witness) is a veritable Germáneutic: an intriguing interpretation and lucid elucidation of what it is (and is not) to be human in the era of big data, of computation beyond the bounds of human intellection, and—spiralling-off from the latter—of intelligent machines (indeed ‘A.I.') that can learn and discern far more than the human, perceiving—and who knows: conceiving?—in the vast void qua bind-spot of our own biological being. _ John Trefry is an architect and the author of the books Plats, Thy Decay Thou Seest By Thy Desire, and Apparitions of the Living. Current works-in-progress: Massive (a novel) & Inanimism (a nonfiction poem). More diminutive writings have appeared in various other outlets. --- Send in a voice message: https://anchor.fm/wake-island/message Support this podcast: https://anchor.fm/wake-island/support

Knowing Neurons interviews Dr. Stephanie White, Professor of Integrative Biology and Physiology at UCLA, about her work studying vocal learning in songbirds as well as her role as the Assistant Director for Undergraduate Education at UCLA's Brain Research Institute. Learn more about Dr. White's research at her lab site [whitelab.ibp.ucla.edu] and explore courses through the Marine Biological Laboratory [mbl.edu/education/courses], including Dr. White's course on neural systems and behavior [mbl.edu/nsb]. Written and produced by Chaoqun Yin and Elizabeth Burnette. Music Used: "Bleeping Demo" by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/7012-bleeping-demo Licensed under Creative Commons: By Attribution 4.0 https://creativecommons.org/licenses/by/4.0/ "Pamgaea" by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/4193-pamgaea Licensed under Creative Commons: By Attribution 4.0 https://creativecommons.org/licenses/by/4.0/ "Study and Relax" by Kevin MacLeod Link: https://incompetech.filmmusic.io/song/5764-study-and-relax Licensed under Creative Commons: By Attribution 4.0 https://creativecommons.org/licenses/by/4.0/

On November 19, 2020, University of Texas San Antonio neuroscientists sat down with Tad Blair for an episode of Neuroscientists Talk Shop. Charles J. Wilson, Francesco Savelli, Todd Troyer and Salma Quraishi chatted with him about mapping brain states on behavior. Dr. Blair is Professor of Behavioral Neuroscience in the Department of Psychology & a member of the Brain Research Institute at UCLA https://www.psych.ucla.edu/faculty/pa...​Charles J. Wilson PhD is Ewing Halsell Chair of Biology at UTSA & Director of the UTSA Neurosciences Institute. https://marlin.life.utsa.edu​Francesco Savelli PhD is Assistant Professor of Biology at UTSA. https://www.utsa.edu/biology/faculty/...​Todd Troyer PhD is Associate Professor of Biology at UTSA. https://www.utsa.edu/biology/faculty/...​Salma Quraishi PhD is Assistant Professor Research at UTSA & Associate Director of the UTSA Neurosciences Institute. https://neuroscience.utsa.edu​Neuroscientists Talk Shop podcast: https://tinyurl.com/yxatz6fq​UTSA Neurosciences Institute:

On November 19, 2020, University of Texas San Antonio neuroscientists sat down with Tad Blair for an episode of Neuroscientists Talk Shop. Charles J. Wilson, Francesco Savelli, Todd Troyer and Salma Quraishi chatted with him about mapping brain states on behavior. Dr. Blair is Professor of Behavioral Neuroscience in the Department of Psychology & a member of the Brain Research Institute at UCLA https://www.psych.ucla.edu/faculty/pa... Charles J. Wilson PhD is Ewing Halsell Chair of Biology at UTSA & Director of the UTSA Neurosciences Institute. https://marlin.life.utsa.edu Francesco Savelli PhD is Assistant Professor of Biology at UTSA. https://www.utsa.edu/biology/faculty/... Todd Troyer PhD is Associate Professor of Biology at UTSA. https://www.utsa.edu/biology/faculty/... Salma Quraishi PhD is Assistant Professor Research at UTSA & Associate Director of the UTSA Neurosciences Institute.

In this episode of the Epigenetics Podcast, we caught up with Professor Isabelle Mansuy, Ph.D., from the University of Zürich and the ETH Zürich, to talk about her work on epigenetic influences on memory formation and inheritance.   Dr. Mansuy received her Ph.D. from the Friedrich Miescher Institute, Basel, Switzerland in 1994. After doing a postdoc at the Center for Neurobiology and Behavior at the Howard Hughes Medical Institute at the Columbia University in New York, she moved to Zürich and became Assistant Professor in Neurobiology at the Department of Biology at the Swiss Federal Institute of Technology in 1998. In 2004 Dr. Mansuy became Professor at the Brain Research Institute of the University Zurich, where, in 2007, she became Managing Director. Since 2013 she has been a full Professor in Neuroepigenetics at the University of Zürich and at the ETH in Zürich.   Dr. Isabelle Mansuy's work centers around the formation of memories and how those memories are inherited. She started to work on memory formation in the beginning of her research career, where she investigated the influence of calcineurin and Zif268 in this process. In the early 2010s she pivoted and transitioned to work on transgenerational epigenetic inheritance. To investigate this field of research she created an unbiased experiment that allowed her to study the transgenerational influence of early life stress, which she was able to observe for across up to 4 generations through the germline.   If you want to learn more about the challenges and obstacles that needed to be overcome to create this novel experimental approach to tackle the questions of and which epigenetic factors might influence transgenerational epigenetic inheritance, don't miss out on this episode.     References Karsten Baumgärtel, David Genoux, … Isabelle M. Mansuy (2008) Control of the establishment of aversive memory by calcineurin and Zif268 (Nature Neuroscience) DOI: 10.1038/nn.2113 Tamara B. Franklin, Holger Russig, … Isabelle M. Mansuy (2010) Epigenetic Transmission of the Impact of Early Stress Across Generations (Biological Psychiatry) DOI: 10.1016/j.biopsych.2010.05.036 Johannes Gräff, Bisrat T. Woldemichael, … Isabelle M. Mansuy (2012) Dynamic histone marks in the hippocampus and cortex facilitate memory consolidation (Nature Communications) DOI: 10.1038/ncomms1997 Eloïse A. Kremer, Niharika Gaur, … Isabelle M. Mansuy (2018) Interplay between TETs and microRNAs in the adult brain for memory formation (Scientific Reports) DOI: 10.1038/s41598-018-19806-z Katharina Gapp, Ali Jawaid, … Isabelle M. Mansuy (2014) Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice (Nature Neuroscience) DOI: 10.1038/nn.3695 Katharina Gapp, Saray Soldado-Magraner, … Isabelle M. Mansuy (2014) Early life stress in fathers improves behavioural flexibility in their offspring (Nature Communications) DOI: 10.1038/ncomms6466 Contact   Active Motif on Twitter Epigenetics Podcast on Twitter Active Motif on Linked-In Active Motif on Facebook eMail: podcast@activemotif.com

Jason and Matthew interview Dr. Gregoire Courtine, the Chief Science Officer of GTX Medical and Professor at the Swiss Federal Institute of Technology. Dr. Courtine has been researching spinal cord stimulation for over 20 years and is hoping to bring that research to clinical relevance with emerging clinical trials with GTX’s LIFT (non-invasive electrical spinal cord stimulation) and GO2 (targeted epidural spinal stimulation). We will continue the conversation in an upcoming Part 2 with Dr. Courtine about the research, the development of GTX and both the possibilities and limitations for functional recovery now and in the future. Grégoire Courtine was originally trained in Mathematics and Physics, but received his PhD degree in Experimental Medicine from the University of Pavia, Italy, and the INSERM Plasticity and Motricity, in France, in 2003. From 2004-2007, he held a Postdoctoral Fellow position at the Brain Research Institute, University of California at Los Angeles (UCLA) under the supervision of Dr. Reggie Edgerton, and was a research associate for the Christopher and Dana Reeve Foundation (CDRF). In 2008, he became Assistant Professor at the faculty of Medicine of the University of Zurich where he established his own research laboratory. In 2012, he was nominated Associate Professor at the Swiss Federal Institute of Technology Lausanne (EPFL) where he holds the International paraplegic foundation (IRP) chair in spinal cord repair at the Center for Neuroprosthetics and the Brain Mind Institute. He published several articles proposing radically new approaches for restoring function after spinal cord injury, which were discussed in national and international press extensively. He received numerous honors and awards such as the 2007 UCLA Chancellor's award for excellence in post-doctoral research and the 2009 Schellenberg Prize for his innovative research in spinal cord injury awarded by the International Foundation of Research in Paraplegia. https://www.gtxmedical.com/ https://people.epfl.ch/gregoire.courtine/?lang=en

Alberto Oliverio"Memoria Festival"https://memoriafestival.it/Sabato 6 giugno 2020, ore 11.00Permanenza e decadenza dei ricordiAlberto Oliverio dialoga con Giuseppe O. LongoIl neuroscienziato Alberto Oliverio e l'epistemologo Giuseppe O. Longo illustrano il significato della memoria e della perdita della memoria all'epoca dei dispositivi informatici, della digitalizzazione, dell'informazione ridondante che ci circonda e della perenne e ininterrotta connessione.Memoria Festival. Il Memoria Festival raddoppia e si reinventa, realizzando uno spin-off digitale trasmesso sui canali social da venerdì 5 a domenica 7 giugno 2020, per anticipare l'appuntamento con il Pro-Memoria Festival, che si svolgerà dal 2 al 4 ottobre. Un percorso di avvicinamento verso l'edizione di ottobre, un vero e proprio raddoppio che sul web prende il via fin da subito attraverso rubriche e iniziative tematiche, in attesa di tornare a vivere la manifestazione, molto presto, in presenzaAlberto OliverioProfessore emerito di Psicobiologia presso l'Università Sapienza di Roma, ha lavorato in numerosi istituti di ricerca internazionali tra cui il Karolinska Institutet di Stoccolma, il Brain Research Institute dell'UCLA a Los Angeles, il Jackson Laboratory nel Maine, il Center for Neurobiology of Learning and Memory dell'Università di California a Irvine. Dal 1976 al 2002 ha diretto l'Istituto di psicobiologia e psicofarmacologia del Consiglio Nazionale delle Ricerche. È stato presidente della Società italiana di Etologia, dell'Istituto italiano di Antropologia e della Società italiana di Neuroetica. È membro dell'Académie européenne internationale des sciences, Parigi, e “premio Antonio Feltrinelli 2017” dell'Accademia nazionale dei Lincei per la “Letteratura e Scienze”.È autore di oltre 200 pubblicazioni scientifiche, di saggi professionali, didattici e di divulgazione tra cui i più recenti riguardano i rapporti tra comportamento e strutture cerebrali (Geografia della mente), i rapporti tra cervello e inconscio (La vita nascosta del cervello) e quelli tra cervello e mente (Cervello). Il suo ultimo saggio è Il cervello che impara. facebook.com/albertooliverio it.linkedin.com/alberto_oliverio pubmed.gov/alberto_oliverio wikipedia/alberto_oliverioIL POSTO DELLE PAROLEascoltare fa pensarehttps://ilpostodelleparole.it/

Today we’re joined by Theofanis Karayannis, Assistant Professor at the Brain Research Institute of the University of Zurich. Theo’s research is currently focused on understanding how circuits in the brain are formed during development and modified by experiences. Working with animal models, Theo segments and classifies the brain regions, then detects cellular signals that make connections throughout and between each region. How? The answer is (relatively) simple: Deep Learning. In this episode we discuss: Adapting DL methods to fit the biological scope of work The distribution of connections that makes neurological decisions in both animals and humans every day The way images of the brain are collected Genetic trackability, and more!

Jamie Feusner M.D., Professor of Psychiatry and Biobehavioral Sciences from Brain Research Institute at UCLA based in the USA participate in Risk Roundup to discuss Machine Learning for Mental Health Diagnosis. Mental Health Crisis The mental health crisis is a silent epidemic. When individuals of all age groups suffer from some form of mental illness, the […] The post Machine Learning For Mental Health Diagnosis appeared first on Risk Group.

Marta Yolanda Díaz-Durán conversa con el Dr. Joaquín Fuster profesor de psiquiatría y de ciencias de la bioconducta en el Neuropsychiatric Institute y en el Brain Research Institute de la Univesity of Californa at Los Angeles. Fuster nos presenta su libro reciente,  Cortex and Mind: Unifying Cognition,  donde expande sus conceptos más allá de la memoria, hacia otras funciones cognitivas, tales como la percepción, la atención, la inteligencia y el lenguaje.  Sostiene que todas las funciones cognitivas están basadas en transacciones nerviosas dentro y entre redes neuronales de representación cognitiva. Además de hablarnos de “El Orden Sensorial: la aportación hayekiana a los modelos neuropsicológicos”  un recuerdo de sus pláticas con el premio nobel Friedrich August von Hayek.

It Didn’t Start with You Show NotesMark is a leading expert in the field of inherited family trauma. He leads workshops, hospitals, conferences and teaching centers around the world. Mark is the author of the book It Didn’t Start with You: How Inherited Family Trauma Shapes Who We Are and How to End the Cycle.Timestamped Notes[00:37] There are fears or anxieties that strike people when they reach a certain age or an event or depression that people never get to the bottom of and symptoms that really come from nowhere. What Mark is learning is the symptoms could actually be the residues of trauma in a person's family history that was biologically inherited from parents or grandparents or even great grandparents. Epigenetics therefore gets into what going there. There are numerous examples of trauma like when a spouse cheats, parents fight or someone dies. Trauma changes people. Any kind of trauma can create an epigenetic change. When trauma occurs it causes a chemical change in the DNA and this can change how genes function sometimes even for generations. A chemical tag will attach to the DNA and tell a cell how to use or ignore a certain gene based on the trauma the body has experienced. The way the genes are affected can change how a person reacts or feels. They can either be reactive or overly sensitive to situations that are similar to the traumas our parents experienced therefore dealing with it better. An example is if a person's grandparents were from a war ton country where there are police everywhere and people being shot. The grand parents would pass forward skill sets like sharper reflexes or quick reaction time to help us survive the trauma they experienced. A stress response can also be inherited along with the skillset.[04:04] People are born with fears and feelings of their parents or grandparents and think that those fears they are theirs. Mark wrote the book because most people do not make the link. These traumas are passed down in gene changes. A chemical change happens to the grandparents which may silence, activate, and turn up or down a gene. It is the gene expression that is passed down. This does not change the DNA but it changes the way the genes express. This can be passed forward for three generations.For years it was known that something like this was happening but it wasn’t until thirteen years ago when Rachel Yehuda a neuroscientist out of Mt Sinai Medical school in New York discovered that the children of holocaust survivors share the same trauma symptoms as the children especially specifically the low levels of cortisone. Cortisone is the stress hormone that gets people back normal after a stressful event. Holocaust survivors and their children experiencing depression and anxiety. She also found the same pattern in the children born to mothers who were pregnant near the World Trade Center when it was attacked. The babies inherited compromised cortisone levels but 16 different genetic markers like being smaller for their gestation period. A couple of years ago Racheal finds that survivors and their children share the exact gene changes in the exact same region of the exact same gene technically the Fkpb five gene.[06:50] This research suggest that traumas are heritable. People are three times more likely to have symptoms of post-traumatic stress disorder if one of their parents had PTSD meaning that those people will struggle with anxiety and depression. The pattern can be observed for two generations in humans but further research indicates three generations is also in effect. This was done using mice and rats which 99% of a similar genetic makeup as humans. It is easy to get a generation of mice in 12-20 weeks whilst with humans it takes 12-20 years.At Emery Medical School at Atlanta, they take male mice and they make them fear cherry blossom scent. Anytime the mice smelled the smell they would get shocked. They noticed that thy were changes in the brain, blood and sperm but specifically in their brain where there were enlarged areas where there was a greater amount of smell receptors so that the mice could protect themselves by detecting the scent at lesser concentrations. That’s the epigenetic change or adaptation. They also saw changes in the sperms and they took some of the sperms and they impregnated female mice that were not shocked. They wanted to see what would in the next generation. They found that the mice in the 2nd and 3rd generation became jumpy and jittery just by smelling the smell. The inherited the stress response without directly experiencing the trauma.[09:09] Traumas are very important. In the contraction of the trauma is the expansion. The traumas themselves are seeking that expansion and therefore keep repeating in sense to show us what is unhealed because ultimately people seek healing. Even after healing Mark thinks that a vestige of the trauma will remain to ensure that people are walking the path that they trust. When people hit on a practice that motivates them, it's these practices that people heal. The experience changes people towards an action and it's through taking that action continually that people heal. In the book Mark tells the story of a woman who wanted to commit suicide. She wanted to be vaporized and incinerated. After interrogation with Mark it turns out she lost most of her family members in Auschwitz.[14:23] People can be born with a body feeling or emotion they can never wrap their heads around. That’s one aspect of knowing one has inherited a feeling. There also some tell signs when things strikes suddenly. An example is realizing a fear, anxiety or symptom that begins suddenly when people reach a certain age or hit a certain milestone like marriage or pregnancy. Mark met a lady whose anxiety problems started once she was pregnant. Her main fear was harming her baby and it turns out her grandmother harmed her child and they were never allowed to talk about it. The lady realized she was carrying her grandmother's experience in her fears and how when something is kept under covers, the traumas find a way to arise more doggedly. When traumas remain unresolved or the healing is incomplete or the people involved are rejected, aspects of the original trauma will repeat itself in the subsequent generation.[15:25] Sometimes children in a family get different traumas. Marks says that it is like an eight cut pizza. The cut pizza represents the traumas in the family. The first boy might take two pieces of the trauma from the father' side and the first girl might take a big piece of pizza from the mother's side and later born children seem to carry trauma that can be even further away maybe a grandparent's trauma. First boys and first girls in a family can take a larger piece of the trauma. In huge traumas like the Holocaust, different kids can carry different aspects of it. One child may carry a fear in the smell of gas while another may be scared that she could lose her children. In the book there was a case of three Lebanese women who both of their grandmothers were given away as child brides to the old men. What passed down was that one sister married a much older man like her grandmother's and the other sister didn't have anything to do with men and she did not marry. The other one shut down every time she dated.[21:10] There are three mechanisms that scientists have illuminated. Three ways in which Trans generational trauma can be observed. The first is DNA methylation where there is methyl residue added on to the DNA and this can be observed for three generations. Another one is non-coding RNAs. Scientists see this in excess amounts for three generations. The third one is called Histone modifications which are added to the proteins. This means that scientists can look at something very physical and see it repeated in three generation. Isabel a researcher at the Brain Research Institute at the University of Zurich traumatized male mice by repeatedly separating them from their mothers. Afterward they exhibited depression like symptoms that were called inhuman. They then took the depressed mice for three generations and dropped them in a bowl of water along with the mice that was not separated from the mother. The mice that were separated from their mother would float and drown whilst the mouse that was not separated would try to get out of the bowl of water. When they dissected the mice they found same trauma symptoms in the 2nd and 3rd generation despite only the 1st generation experiencing the trauma. The researchers found abnormally high numbers of small non coding micro RNAs. Although the mice in the 3rd generation also expressed the same symptoms as their fathers and grandfathers, they did not have the elevated numbers of the micro RNAs. This allowed researcher to speculate that there is a three generational link but perhaps not beyond that. Currently there are studies with worms where they can see generational links for 14 generations so there is still a possibility of going beyond 3 generations.[25:27] The largest trauma that Mark has worked with is attachment. This can come in two ways, experiencing one's own break from the mother or inheriting ones fathers or mother break with his or her mother. Some of the male mice that were separated from their mothers did not express the behavioral changes themselves, they epigenetically transmitted the behavioral change to their female offspring's. Father's trauma could go into either direction.Once a person has figured out their trauma language, they need to have a new experience that is powerful enough to override the trauma response that lives inside. This experience needs to be emotionally important. The idea is to steal traction away from the trauma cycle that is in the mid brain. The experience needs to engage the Prefrontal Cortex and change the brain because energy is being pulled out from the limbic brain, stress response or trauma. This leads to the rewiring of new pathways as well as stimulating the release of a few good neurotransmitters like Serotonin, Dopamine and Gamma-amino butyric. These hormones are necessary to get pregnant for couples. The genes express can be affected positively by doing that therefore reducing the likelihood of your child picking up trauma. When the mice were transferred in a positive environment they did not pass it down to their offspring.[35:26] Mark's book teaches the reader how to become a detective, to uncover the clues or the behaviors that repeat. There is a trauma language that a body speaks and there is also trauma language of a repeating self-destructive behaviors that people keep making. People need to learn how to listen to such language and symptoms. The book then leads the reader to where the language originated from the family history. With all that information, breaking the cycle is possible. There are many questions in the book that help the reader unearth their language. Readers are encouraged to have support before starting the journey.Knowing what's going on expands our knowledge and the resources to deal with our situations. Not knowing makes one live in a cloud of misery where one thinks everything bad happens to him. The book is very freeing because it allows people to shake the family tree and see what falls out. If one ignores the past, it will come and haunt them later in the future. Exploring it gives options of breaking the disruptive pattern. The trauma itself contains the seed of expansion. In the contraction lives the expansion.Connect with Markhttps://www.markwolynn.com/mark-wolynn/- Personal websiteResourcesIt Didn’t Start With You: How Inherited Family Trauma Shapes Who We Are and How to End the Cycle- Mark Wolynn See acast.com/privacy for privacy and opt-out information.

Hypnosis, Racism, Deer, Freestyle Rap, and Drugs! What more do you want? Today we discuss GET OUT with Open Mike Eagle and Dr. Rafael Romero from the Brain Research Institute. Enjoy! Check out more from Open Mike Eagle at mikeeagle.net and email us at BadScience@Seeker.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Henry Kennedy (Stem-Cell and Brain Research Institute, Lyon) discusses his work on the anatomical structure of the primate cortex. Interviewed by Paul Verschure and Tony Prescott.

Anna-Sophia Wahl from the Brain Research Institute at the Swiss Federal Institute of Technology, in Zurich, talks with us about using optogenetics to help restore motor controls after suffering a stroke. For more information, including materials discussed during this episode, visit ParsingScience.org. Subscribe: iTunes | Android | RSS.

Dr. Chris Evans talks with Jonathan about how people get addicted to opioids, why addiction is so hard to kick, and what we can do about this national crisis. Dr. Evans is Director of the Brain Research Institute at UCLA and the Hatos Centre for Neuropharmacology.  Find out what today's guest and former guests are up to by following us on Instagram and Twitter @CuriousWithJVN.   Transcripts for each episode are available at JonathanVanNess.com. Check out Getting Curious merch at PodSwag.com. Listen to more music from Quiñ by heading over to TheQuinCat.com. Jonathan is on Instagram and Twitter @JVN and @Jonathan.Vanness on Facebook.

When we heave a deep sigh, there can be many reasons and interpretations, but an unconscious sigh is actually a life-sustaining reflex that helps preserve lung function. Now for the first time, a team of researchers at UCLA and Stanford have pinpointed the origin of the sighing reflex in the brain. Neurobiologist Jack Feldman of UCLA’s Brain Research Institute says this study gave researchers an opportunity to identify a circuit that’s responsible for an easily identifiable behavior. "And this is one of the holy grails now of neuroscience – is to try and understand how circuits are organized. And the problem that most scientists face is that most of the problems that we’re interested in are just too complicated. With breathing, we have a direct readout of what the brain is doing, so we have a great system for interrogating what’s going on inside the brain. And the number of neurons we had identified were about 200 per side, which is not a lot of neurons, so it was tractable." This discovery may also help doctors treat patients with breathing disorders.

Aaron Blaisdell is a Professor in Learning & Behavior and Behavioral Neuroscience in the UCLA Psychology Department. He presides over the Comparative Cognition Lab, studying cognitive processes in rats, pigeons, hermit crabs, and humans.Aaron knows the best way to carry a rat is on your shoulderAfter receiving his BA and MA in Biological Anthropology (at SUNY Stony Brook and Kent State University, respectively), Aaron realized that animal cognition was even more interesting than dead humans. So he trekked on over to SUNY Binghamton for his Ph.D. in Experimental Psychology with  Ralph Miller, where he studied learning, memory, and temporal cognition in the rat. This was followed by a brief stint as an NRSA Postdoctoral Fellow with Bob Cook, an expert on Avian Visual Cognition at Tufts University, where he learned how pigeons perceive and think about the world. In 2001, he emigrated to the climatological and cultural paradise of sunny LA where he has remained ever since.  A second interest of Aaron’s is in how human ancestry and evolution can inform us about health and well being in the modern world. He is currently studying the interaction between diet and cognition. He is a founding member and Past President of the Ancestral Health Society, Past President of the International Society for Comparative Psychology, an Editor-in-Chief of the Journal of Evolution and Health, and a member of the Brain Research Institute, the Integrative Center for Learning & Memory, and the Evolutionary Medicine program all at UCLA.We talked about a lot of different things, including reasoning in rats, sensory preconditioning, how diet affects cognition, representation in rat memory and Aaron's crowdfunded research proposal.Thanks again to Red Arms for letting me mash up their music in the closing theme. Buy their music now.mp3 download

Dr. S. Thomas (Tom) Carmichael is a Neurologist, as well as Professor and Vice Chair for Research in the Neurology Department at the University of California, Los Angeles. He is also a Member of the Brain Research Institute and Co-Director of the UCLA Broad Stem Cell Center. Tom received his MD and PhD from Washington University School of Medicine. He completed a Neurology residency there, followed by a Howard Hughes Medical Institute Postdoctoral Fellowship at UCLA. He then joined the faculty at UCLA where he remains today. Tom is here with us today to tell us all about his journey through life and science.