Podcast appearances and mentions of michelle flynn

Welcome to We Have A Meeting — the UK's go-to podcast for high-performance sales, mindset mastery, and personal development. Hosted by sales experts Jack Frimston and Zac Thompson, this podcast delivers unfiltered conversations with world-class entrepreneurs, thought leaders, and mental fitness coaches. From neuroscience-backed strategies to real-world sales tactics, every episode is designed to help you sell smarter, lead better, and live with purpose.In this episode, we're joined by Michelle Flynn — certified mental fitness coach, breathwork expert, and founder of Michelle Flynn Coaching. Michelle shares the most powerful breathwork techniques to calm anxiety, build resilience, and unlock peak performance. Whether you're looking to regulate your nervous system before a big sales pitch or simply show up more powerfully in your life, Michelle's simple, science-backed practices can help you breathe your way to a better you.

The Recruiter Startup Podcast kicks off 2025 with a conversation with Michelle Flynn, a recruitment veteran turned coach who host Dualta Doherty compares to the 'Billions' character Wendy Rhoades—and, after hearing her thoughts on the industry, it is easy to understand why. In this episode, Michelle shares her journey from agency recruitment to coaching, offering insights on how leaders can balance work and life, build resilience, achieve peak performance and navigate the ups and downs of leadership in recruitment. Tune in!

Hour four of DJ & PK for December 20, 2024: Kevin Graham talking football Michell Flynn, The Road Home Feedback of the Day

In this episode of Baby Tribe, we discuss experiences related to birth trauma, which include references to sexual abuse. This content may be challenging for some listeners, especially those with similar lived experiences. If you or someone you know is affected by these issues, please consider reaching out to a trusted professional or support organization. Years ago, Michelle Flynn, a clinical psychotherapist specializing in maternal mental health, witnessed firsthand how birth trauma could transform a joyful moment into a complex emotional struggle. Her journey led her to explore the intricacies of birth trauma and how it deeply affects mothers and families. Join us as Michelle shares her personal insights and expertise, uncovering the layers of trauma that exist beyond the surface events. From the role of the autonomic nervous system to how trauma memories manifest physically, Michelle opens a path to understanding these profound experiences. Throughout the episode, we navigate the symptoms and causes of birth trauma, bringing to light the concept of "trauma time" and its impact on the nervous system. By differentiating between postnatal anxiety and PTSD, we provide clarity on effective treatments and the spectrum of trauma symptoms. We expand the conversation to include reproductive trauma across various stages, such as IVF and pregnancy loss. Michelle emphasizes the systemic factors that contribute to trauma, particularly for those with previous trauma or from minority backgrounds, urging for a more sensitive and informed healthcare approach.  Communication emerges as a pivotal theme, underscoring the importance of trauma-informed care in empowering patients and preventing avoidable trauma. Through personal stories and professional insights, we stress the need for systemic support for healthcare workers to foster resilience and empathy. By the episode's conclusion, listeners are reassured of the potential for healing through tailored interventions, including EMDR and somatic experiencing. This conversation is essential for anyone seeking to understand and support those affected by birth trauma, providing insights into effective coping and recovery strategies. You can reach Michelle at: https://ancroibeagpsychotherapy.ie/ Michelle's Instagram: https://www.instagram.com/ancroibeag/  Proudly Sponsored by: www.happytummy.ie Learn more about your ad choices. Visit megaphone.fm/adchoices

Health anxiety during pregnancy and the postpartum is a very real struggle for many people. My guest today joins us to share her experience and what she's seeing from clients in her practice. You'll learn how to notice perinatal health anxiety and what to do about it. Join us to learn more! Michelle Flynn is a fully accredited perinatal psychotherapist and certified infant massage instructor based in Dublin, Ireland. She specializes in supporting parents at all stages of their parenting journey from conception through birth and postpartum. She works with a national organization providing psychotherapy to survivors of childhood sexual abuse and also teaches in a master's program. Following her experience of perinatal anxiety and her struggle to access appropriate mental health support, Michelle turned her focus to perinatal mental health and set up her private practice, An Croi Beag Psychotherapy (“Little Heart” in Irish). Through her private psychotherapy practice and her infant massage groups, Michelle hopes to further support parents in perinatal distress, raise awareness about perinatal mood and anxiety disorders, and improve access to mental health services for birthing people.  Show Highlights: Michelle's journey into perinatal mental health and her overwhelming anxiety during her difficult first pregnancy Michelle's experience with healthcare providers who dismissed her concerns and made her feel invalidated and unsafe Even mental health professionals feel shame and stigma about asking for help! Subsequent pregnancies brought Michelle two more babies for “three under three,” but those were different from her first pregnancy. The conversations we need to have with young people about pregnancy, birth, and postpartum so we can normalize it and remove the shame and stigma Understanding the mental health system in Ireland—and how things are beginning to improve What Michelle sees in her patients and their experiences The challenges in treating health anxiety The narrative around motherhood—and why we don't open up when things go wrong Michelle's advice about identifying health anxiety for yourself, and what to do next Resources: Connect with Michelle Flynn: Website, Email, and Instagram Please find resources in English and Spanish at Postpartum Support International, or by phone/text at 1-800-944-4773. There are many free resources, like online support groups, peer mentors, a specialist provider directory, and perinatal mental health training for therapists, physicians, nurses, doulas, and anyone who wants to better support people for whom they provide services.  You can also follow PSI on social media: Instagram, Facebook, and most other platforms Visit www.postpartum.net/professionals/certificate-trainings/ for information on the grief course.   Visit my website, www.wellmindperinatal.com, for more information, resources, and courses you can take today! Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of Pints of View Gary Goldsmith talks to Michelle Flynn about her career journey in recruitment. They discuss Michelle's early career at Computer Futures where she was a top biller, her time running recruitment in-house for various tech companies, and her transition into well-being coaching after experiencing some health issues of her own.   In this episode you will hear: Michelle's story of falling into recruitment and her success at Computer Futures How she went on to run the talent acquisition teams in-house for multiple companies Her experience starting a shoe company with her husband Her work now in well-being coaching and supporting recruiters' mental health   For more information about this episode, Gary's advisory services or the RDLC please email us on POV@garys.world   Follow us on Instagram https://www.instagram.com/pints_of_view_pod/   Pints Of View is the podcast hosted by socialite, in-demand Non-Exec Director, recruitment legend and all-around nice guy Gary Goldsmith. In this podcast, Gary opens up his eclectic Black Book of friends that ranges from international footballers, high street moguls, champion boxers, investment oracles, national team coaches, royal correspondents, business leaders, military special forces, sports club owners, scale-up experts and even conspiracy theorists with a sense of humour!  They're all interesting, they've all got different stories, they've all got different backgrounds and they have all got lessons that you will learn a great deal from, alongside a fair few belly laughs too.  Plus, as well as the amazing guests, you will also learn that there is a lot more to Gary Goldsmith than what the headlines might have had you believe! Far from just being a loveable rogue and famous royal Uncle, there are insights and wisdom shared that reveal why Gary has been integral to hundreds of millions of pounds of business growth over the years.   So, join us for some real, raw and interesting chats down at the pub - yes, this show is really shot on location at an actual, working West End boozer!

This episode focuses on defining and cultivating a positive life. Guest Michelle Flynn and host Sal Jefferies discuss the importance of good habits for happiness and health. They cover several key topics:Food and Nutrition: Eating real, whole foods vs. processed foods. Understanding the gut-brain connection. Starting with basic healthy habits.Movement: Incorporating enjoyable movement rather than traditional "exercise." Walking, functional movements. Long-term consistency over short-term intensity.Sleep: Getting enough sleep, quality sleep, regular rhythm. Breathing techniques to improve sleep.Connection: Combating loneliness, finding your "people." Michelle's experience starting a women's group. The power of taking small steps to connect.Relaxation: Self-care, downregulation, giving yourself permission to take time. Small consistent actions.Some more notes of key points and the areas to work on are as follows:Food and NutritionReal, whole foods are best - avoid processed foodsGut health impacts brain health and mental wellbeingStart with basic healthy habits like eating more veggiesMovementFind enjoyable activities like walking or dancing rather than traditional gym exerciseAim for long-term consistency over short bursts of high intensityFunctional movements like carrying groceries build strengthSleepPrioritize getting enough sleep, quality sleep, and a consistent rhythmUse breathing techniques to relax into deeper sleep more quicklyTry mouth taping to promote nasal breathingConnectionCombat loneliness by finding people with shared interests/valuesMichelle's experience starting a women's group by just taking small stepsLook for local groups on Facebook or EventbriteRelaxationMake time for self-care through activities like reading, yoga, massageGive yourself permission to take breaks and unwindStart small - even 2 minutes of breathwork helpsOther NotesRemember to treat your health holisticallyGrocery store layouts are designed to influence purchasesCheck out episodes with Leanne Weaver and April BakerJames Clear's work on habit formationMichelle's BIOMichelle is a Cognitive Behavioural Therapy (CBT) Practitioner, Certified International Health Coach, Integrative Nutrition Health Coach with a Gut Health Certification, Experienced Life Coach and Mental Health in Recruitment Ambassador.Michelle works with individuals and companies to help them understand their health and happiness goals (e.g. healthy diet, weight loss, reducing stress, increasing exercise, better quality of sleep, improved relationships, financial stability and exciting careers).Contact Michelle and see more her websiteGet in touch with SalIf this episode has caught your attention and you wish to learn more, then please contact me. I offer a free 20 min call where we can discuss a challenge your facing and how I may be able to help you.

Are you pregnant, thinking about becoming pregnant or trying to become pregnant and dealing with anxiety? Or did you experience anxiety in pregnancy? Perhaps it was anxiety due to the physical symptoms, or because you arrived at pregnancy after experiencing reproductive trauma, with lots of worry around conception and fertility, or loss, or because for whatever reason, the hormones in pregnancy just drove you into fight or flight mode. Maybe you thought you'd feel amazing and excited and at ease (which is the picture often painted of pregnancy) and in reality you were incredibly on edge, which is normal though not widely discussed. This episode where we explore perinatal anxiety is for you. I am joined by Michelle Flynn, perinatal psychotherapist and founder of An Croi Beag Psychotherapy. She has a wonderful gentle way about exploring this topic and I hope it's both comforting, useful and of course validating for anyone going through this or having gone through it in the past. To read more about my own parenting experience, sign up to my substack HERE. Support this show http://supporter.acast.com/owningittheanxietypodcast. Own your anxiety as and when it happens with Owning It: Real Time. The situation specific series of audio guides that helps you move through your most anxious moments. Available now on Acast+ https://plus.acast.com/s/owningittheanxietypodcast. Hosted on Acast. See acast.com/privacy for more information.

PJ talks to Michelle Flynn, Career Guidance counselor & advisor who says too many are dismissive about what is an important exam. Hosted on Acast. See acast.com/privacy for more information.

This week we have a special interview with Kylene Beers about her newly released second edition of When Kids Can't Read: What Teachers Can Do.Michelle Flynn joins her to talk about how Kylene's thinking has changed over the past 20 years since the first edition, what new material is included, and how this book speaks to the urgency around reading. Stay tuned after their conversation for a sample from the second chapter of the audiobook version of When Kids Can't Read, second edition.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

With the state exams underway, many students will be coming home to their parents delighted or underwhelmed with their performance. What should you do when your son or daughter's first few exams did not go to plan? Our own Méabh has been chatting to Michelle Flynn from Career Hub Limerick. Hosted on Acast. See acast.com/privacy for more information.

PJ gets tips to help Leaving Cert students from Michelle Flynn of careerhub.ie Alex Linehan of NextStepUni.com then tells him his story of how he turned an exam nightmare into a business. Hosted on Acast. See acast.com/privacy for more information.

This week we have a special interview with Kylene Beers about her newly released second edition of When Kids Can't Read: What Teachers Can Do.Michelle Flynn joins her to talk about how Kylene's thinking has changed over the past 20 years since the first edition, what new material is included, and how this book speaks to the urgency around reading. Stay tuned after their conversation for a sample from the second chapter of the audiobook version of When Kids Can't Read, second edition.As always, a transcript of this episode is available at blog.heinemann.com©Heinemann Publishing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

This episode features a conversation with Michelle Flynn, the executive director of the nonprofit The Road Home, and Pete Codella, Go Utah's managing director of business services. The nonprofit organization provides emergency shelter, supportive services, and housing assistance to help individuals and families step out of homelessness. Flynn tells listeners why she has been with The Road Home for more than two decades, what first drew her to a service-oriented career, and shares the organization's long-standing and rich history. She informs the public what the organization is doing to combat the affordable housing situation in Utah, the number of individuals The Road Home assists annually, and how the coronavirus pandemic impacted the organization. Flynn shares how the Salt Valley compares to other metropolitan areas regarding homelessness, tells listeners how they can get involved during this season of giving, and much more.

In 2020, the United States Interagency Council on Homelessness reported that an estimated 3,131 Utah residents experienced homelessness on any given day. And, according to data shared by the Office of Homeless Services under the Utah Department of Workforce Services, 24,037 people accessed homelessness services in Utah sometime during 2021. Clearly, homelessness is a grave concern for many Utah women and families.Recently, the Utah Women & Leadership Project published a research snapshot about homelessness among Utah women. Dr. Susan Madsen, Founding Director of the Utah Women & Leadership Project, is joined by Dr. Emily Darowski, Associate Director of the UWLP; Joseph Jensen, Data Manager for the Utah Office of Homeless Services; and Michelle Flynn, Executive Director of The Road Home. Support the show

What do 45 Special Bureau of Investigation Agents do reporting to a professor? Fight one of the most heinous crimes in our society – HUMAN TRAFFICKING! Dr. Osborne recently went back to teaching as an associate professor of management and the chair of business administration at Campbell University's Lundy-Fetterman School of Business after years as the Chief Deputy Commissioner for the North Carolina Department of Insurance where she led those aforementioned SBI Agents. Starting as a classical pianist she has followed an unconventional path. Her original research for her doctorate guided her into the world of human trafficking the third largest illegal industry in the world behind counterfeiting and drugs. Her book The Maid tells the story of one young girl involved in this multi-billion-dollar industry. To buy The Maid: https://amzn.to/3xmzSVD

Michelle Flynn is a clean and simple scrapbooker who loves Project Life and smaller formats. You'll find tons of white in her projects, along with harmonious and monochromatic color schemes. And as a current member of the Elle's Studio team, their products feature extensively in her recent work. In this episode you'll get to hear the why and how behind Michelle's creative process. We're thrilled to have her as our October featured artist. See the full show notes for this episode at simplescrapper.com/syw190. ♥ Love the podcast? Join our creative community today. 

It is important to know that no matter what happens, there are always other options, and other paths you can go down to get your dream course. We speak to Julie O'Connor from Synergie, and Michelle Flynn from Career Hub Limerick to give some advice about the results, and what to do next… Our GDPR privacy policy was updated on August 8, 2022. Visit acast.com/privacy for more information.

When you hear the phrase "people experiencing homelessness", what pops into your mind? For many people, it's a very negative image. But The Road Home Executive Director Michelle Flynn sat down with Inside Sources to shine a light on who those folks really are, bust some myths about this misunderstood population, and talk about what we can do better to get more people into housing. See omnystudio.com/listener for privacy information.

This is Derek Miller Speaking on Business. The Road Home is a Salt Lake City-based organization that brings safe refuge to people otherwise living on the streets and in the extremes of weather. Michelle Flynn, Executive Director of the Road Home, tells us what they do to help those in need. MICHELLE FLYNN The Road Home's mission is to help people step out of homelessness and move back into our community. We start by providing basic needs while immediately working with them to develop a housing plan. Our programs connect people with resources to help them integrate back into the community, from emergency shelter at the Midvale Family Resource Center, to the Gail Miller Resource Center and the Men's Resource Center in Salt Lake. We also provide programs to move families and individuals out of emergency shelters and into permanent homes. The Road Home's Rapid Re-Housing program helps individuals, families, and veterans move into homes quickly and then remain housed. Services can include rental assistance, basic needs for the home, and case management that connects people to affordable childcare, public benefits, employment opportunities, and food security. We also partner with the U.S. Department of Veterans Affairs and others to help end veteran homelessness. DEREK MILLER The Road Home is currently seeking landlords who want to provide housing opportunities to families, individuals, and veterans. If you can bring some holiday cheer, please contact TheRoadHome.org. I'm Derek Miller with the Salt Lake Chamber, Speaking on Business. Originally Aired: December 15, 2021

Catch our live Ask The Expert session with Michelle Flynn to get advice that will help you understand how to master mindfulness. Michelle is a Certified International Health Coach (CIHC), an Integrative Nutrition Health Coach (INHC) and Mental Health First Aider. Michelle works with individuals and companies to help them understand their health and happiness goals (e.g. healthy diet, weight loss, reducing stress, increasing exercise, better quality of sleep, improved relationships and exciting careers), and then support them as they put in place the habits to achieve and sustain them through 1-2-1 health coaching sessions, group meet-ups, presentations, workshops and company health & well-being programmes. Our fully interactive Q&A sessions are hosted by a different business expert every day. Pick up valuable tips and advice and discover practical positive steps you can take in the weeks ahead. You ask all the questions — add yours in the comments section of YouTube or Facebook or use the #QBATE hashtag on Twitter. #QuickBooks The world's largest workforce works for themselves. We work for them by providing smarter business tools. QuickBooks is always backing you. https://quickbooks.intuit.com/uk/ Subscribe to our YouTube channel: https://bit.ly/2ycNB3g Follow us on Facebook: https://www.facebook.com/QuickBooksUK/ Follow us on Twitter: https://twitter.com/QuickBooksUK Follow us on Instagram: https://www.instagram.com/quickbooksuk/

In the latest instalment of the Recruitment Leadership Podcast, your host Alison Humphries is joined by Michelle Flynn, former recruitment Director and Founder of Michelle Flynn Coaching.    After working in recruitment for over 16 years and owning her own recruitment business, Michelle is now a qualified CBT trainer and integrative nutritional health coach.   She works with individuals and companies to help them understand their health and happiness goals, supporting them as they put in place the habits to make achievable and sustainable changes.   In this episode, Alison and Michelle discuss mental health and wellbeing management in the context of the recruitment industry; covering key areas and providing expert advice, this episode is not one to be missed.    Timestamped guide:   00:51 - How did your career path lead you to be counselling and consulting in this area?   3:57 - Why has the topic of mental health and wellbeing taken flight in the recruitment sector?   5:45 - We have a very young age profile across the industry with a lot of responsibility and expectations, do you think that is a factor?   9:02 - What actionable changes would you suggest many recruitment business owners would make?   13:24 - What kind of things should managers look out for if somebody isn't approaching them for help?   16:09 - Are there any policy level things that you think at a company level, if somebody changed their policy it would overall have a positive effect on their staff?   21:02 - What advice do you have differentiating the blurred lines between real mental health issues, or someone taking advantage?   24:29 - Advice on using the Bradford score    25:40 - Can you talk us through how you make an assessment for mental health?   30:22 - Useful resources    If you would like to find out how Michelle Flynn Coaching can help to support your business, visit the website or connect with Michelle directly on LinkedIn:  

Featured speaker: Michelle Flynn, CBT Practitioner & Certified Health Coach Recruitment will always be a sales business. As we navigate the path of recovery, how can business leaders help their people adapt to the new world of work and deliver against their high targets while providing excellent mental health and well-being support? We spoke to REC business partner and CBT Practitioner & Certified Health Coach Michelle Flynn on the practical steps agency owners and business leaders can take to manage the wellbeing and resilience of their staff. An ex-recruiter herself, Michelle brings in her wealth of knowledge and diverse experience on what our industry can do to tackle this issue. Tune in to hear about: • How do we address the challenge of mental health as we build back? • What challenges do recruitment businesses face around employee mental health and wellbeing? • How can businesses support their staff with mental health and resilience? • Top tips for health and wellbeing for recruiters to improve mindset and performance • Practical tips for agency owners on physical, personal and emotional recovery Visit REC's mental health hub for more resources: https://www.rec.uk.com/our-view/topics/mental-health-and-wellbeing/mental-health-and-wellbeing-focus Find out more about how Michelle can help you, your staff and your business here: https://michelleflynncoaching.com/

Catch our live Ask The Expert session with Michelle Flynn to get advice that will help you understand how to master mindfulness. Michelle is a Certified International Health Coach (CIHC), an Integrative Nutrition Health Coach (INHC) and Mental Health First Aider. Michelle works with individuals and companies to help them understand their health and happiness goals (e.g. healthy diet, weight loss, reducing stress, increasing exercise, better quality of sleep, improved relationships and exciting careers), and then support them as they put in place the habits to achieve and sustain them through 1-2-1 health coaching sessions, group meet-ups, presentations, workshops and company health & well-being programmes. Our fully interactive Q&A sessions are hosted by a different business expert every day. Pick up valuable tips and advice and discover practical positive steps you can take in the weeks ahead. You ask all the questions — add yours in the comments section of YouTube or Facebook or use the #QBATE​ hashtag on Twitter. #QuickBooks​ The world's largest workforce works for themselves. We work for them by providing smarter business tools. QuickBooks is always backing you. https://quickbooks.intuit.com/uk/​ Subscribe to our YouTube channel: https://bit.ly/2ycNB3g​ Follow us on Facebook: https://www.facebook.com/QuickBooksUK/ ​Follow us on Twitter: https://twitter.com/QuickBooksUK ​Follow us on Instagram: https://www.instagram.com/quickbooksuk/

Joining Meg this week is guest Michelle Flynn of Michelle Flynn Coaching.

Catch our live Ask The Expert session with Michelle Flynn to get advice that will help you understand how to master mindfulness. Michelle is a Certified International Health Coach (CIHC), an Integrative Nutrition Health Coach (INHC) and Mental Health First Aider. Michelle works with individuals and companies to help them understand their health and happiness goals (e.g. healthy diet, weight loss, reducing stress, increasing exercise, better quality of sleep, improved relationships and exciting careers), and then support them as they put in place the habits to achieve and sustain them through 1-2-1 health coaching sessions, group meet-ups, presentations, workshops and company health & well-being programmes. Our fully interactive Q&A sessions are hosted by a different business expert every day. Pick up valuable tips and advice and discover practical positive steps you can take in the weeks ahead. You ask all the questions — add yours in the comments section of YouTube or Facebook or use the #QBATE​ hashtag on Twitter. #QuickBooks​ The world's largest workforce works for themselves. We work for them by providing smarter business tools. QuickBooks is always backing you. https://quickbooks.intuit.com/uk/​ Subscribe to our YouTube channel: https://bit.ly/2ycNB3g​ Follow us on Facebook: https://www.facebook.com/QuickBooksUK/​ Follow us on Twitter: https://twitter.com/QuickBooksUK​ Follow us on Instagram: https://www.instagram.com/quickbooksuk/

Catch our live Ask The Expert session with Michelle Flynn to get advice that will help you understand your health and happiness goals. Michelle is a Certified International Health Coach (CIHC), an Integrative Nutrition Health Coach (INHC) and Mental Health First Aider. Michelle works with individuals and companies to help them understand their health and happiness goals (e.g. healthy diet, weight loss, reducing stress, increasing exercise, better quality of sleep, improved relationships and exciting careers), and then support them as they put in place the habits to achieve and sustain them through 1-2-1 health coaching sessions, group meet-ups, presentations, workshops and company health & well-being programmes. Our fully interactive Q&A sessions are hosted by a different business expert every day. Pick up valuable tips and advice and discover practical positive steps you can take in the weeks ahead. You ask all the questions — add yours in the comments section of YouTube or Facebook or use the #QBATE hashtag on Twitter. #QuickBooks The world's largest workforce works for themselves. We work for them by providing smarter business tools. QuickBooks is always backing you. https://quickbooks.intuit.com/uk/ Subscribe to our YouTube channel: https://bit.ly/2ycNB3g Follow us on Facebook: https://www.facebook.com/QuickBooksUK/ Follow us on Twitter: https://twitter.com/QuickBooksUK Follow us on Instagram: https://www.instagram.com/quickbooksuk/

The demands on educators in this moment are more than anyone could have ever imagined. Routines for teaching and learning, with children AND with colleagues, have completely been turned upside down. The time crunches are real and the need for growing as professionals in the name of students still remains. So, where does professional development fit in our current reality? What do educators need most? What formats are the most flexible?Today we hear a conversation between Michelle Flynn and Jaclyn Karabinas from the Heinemann Professional Development team. Michelle and Jaclyn bring a variety of perspectives on what they are hearing from teachers and schools about their needs, as well as from our authors about their observations and experiences working virtually with educators and students over the last 6 months. To learn about our schedule of webinars, virtual workshops, and options for custom virtual PD visit Heinemann.com/pd

This month on Episode 16 of the Discover CircRes podcast, host Cindy St. Hilaire highlights four featured articles from the August 28 and September 11 issues of Circulation Research. This episode features an in-depth conversation with Drs Andrew Murphy and Michelle Flynn from The Baker Heart and Diabetes Institute at Monash University in Melbourne, Australia regarding their study Transient Intermittent Hyperglycemia Accelerates Atherosclerosis By Promoting Myelopoiesis.   Article highlights:   Fish, et al. KRAS Mutations Cause Arteriovenous Malformations   Ehling, et al. B55a in Vascular Biology   Barrett, et al.  Platelet Activity and Vascular Health in COVID-19   Furmanik, et al. Nox5 in VSMC Phenotype and Calcification     Cindy St. Hilaire:  Hi. Welcome to Discover CircRes, the podcast to the American Heart Association's journal, Circulation Research. I'm your host, Dr Cindy St. Hilaire, from the Vascular Medicine Institute at the University of Pittsburgh. And today I'm going to share with you four articles selected from our late August and early September issues of Circulation Research. I'm also going to speak with Drs Andrew Murphy and Michelle Flynn from The Baker Heart and Diabetes Institute at Monash University in Melbourne, Australia regarding their study Transient Intermittent Hyperglycemia Accelerates Atherosclerosis By Promoting Myelopoiesis. So first, the highlights. The first article I'm sharing with you is titled Somatic Gain of KRAS Function in the Endothelium is Sufficient to Cause Vascular Malformations that Require MEK but not PI 3-Kinase Signaling. First authors are Jason Fish, Carlos Perfecto Flores-Suarez, and Emily Boudreau. And the corresponding authors are Jason Fish and Joshua Wythe, and they're from University of Toronto and Baylor College of Medicine. Arterial venous malformations, or AVMs, are tangles of blood vessels in which the arteries are directly connected to the veins without going through the capillary bed. These are thought to be present from birth and when they occur in the brain, they can cause an array of symptoms such as headaches or seizures, but they are also the leading cause of hemorrhagic stroke in children and young adults. This is because the venous system is not muscularized to respond to the pressure forces that are exerted on arteries. These pressure forces cause distension and eventual leakage at the site of AVMs. Vessel tissue recovered from patients undergoing AVM repair has been shown to contain sematic gain of function mutations in the protein RAS GTPase, which is encoded by the gene, KRAS. However, whether these gain of function mutations directly cause AVMs has not been established. This study now shows that endothelial cells with constitutive expression of gain of function KRAS mutants in mice and zebra fish causes vascular malformations and cranial hemorrhages. Inhibiting a MEK kinase, which is a downstream mediator of RAS signaling, prevented hemorrhages in the mutant KRAS carrying fish. In vitro studies also showed that overactive RAS GTPase protein caused excessive angiogenic behavior of endothelial cells. Together, this work confirms the link between gain of function KRAS mutations and brain AVMs, and suggests that MEK inhibition could be a potential strategy for nonsurgical treatment. The second article I want to share with you is titled B55a/PP2A Limits Endothelial Cell Apoptosis During Vascular Remodeling: A Complimentary Approach To Kill Pathological Vessels. The first author is Manuel Ehling and the corresponding author is Massimiliano Mazzone. And the work was completed at Leuven Center for Cancer Biology in Belgium. Building a mammalian vascular system is a dynamic process that is dependent on both growth of new vessels, as well as the pruning of unwanted ones. But while much is known about molecular mechanisms underlying angiogenesis, comparatively little is understood about the mechanisms regulating vascular pruning. This study discovered that suppression of the protein phosphatase 2 subunit, B55A, is a key protein regulating the pruning process. They found that in mouse vascular development, B55a is widely expressed. However, in adult mice expression is restricted only to sites of active angiogenesis. Deletion of B55a in mice caused death in mid to late stages of embryogenesis as a result of vascular problems that appeared to be due to excessive vessel pruning. Switching off B55a in adult mice when the vascular development is for the most part complete did not cause any apparent problems. They did find though, that inhibition of B55a significantly delayed growth of tumors that form from the injection of cancerous cells. Inhibition of B55a produced tumors with less dense vasculature and reduced metastatic potential. Thus, the author suggests that ramping up blood vessel pruning, be it inhibition of B55a, could be a novel strategy for limiting tumor growth. The next article I want to share is titled Platelet and Vascular Biomarkers Associated With Thrombosis and Death in COVID-19. The first author is Tessa Barrett and the corresponding author is Jeffrey Berger, and they're from New York University. Our knowledge of the complications of COVID-19 is evolving every day. Laboratory testing done to date suggests that approximately 30% of hospitalized COVID-19 patients go on to develop thrombotic events. Platelets are central characters in both arterial and venous thrombosis, and it is known that virus platelet interactions can stimulate a pro-coagulant and inflammatory state during a viral infection. Further, recent studies have reported COVID-19 patients have hyperactive platelets and autopsies of COVID-19 patients exhibit micro and macro thrombi across vascular beds, even in patients without clinical thrombosis. This group then hypothesized that biomarkers of platelet activation are associated with incident thrombosis or death in COVID-19 patients. To test this, they randomly selected 100 COVID-19 positive patients and analyzed banked samples collected on the day of the COVID-19 diagnosis to investigate in vivo platelet activity, as well as vascular health biomarkers. They show for the first time that biomarkers of platelet activation at the time of diagnosis are associated with thrombosis or death in patients hospitalized with COVID-19. Their findings suggest platelet activation mechanisms may contribute to adverse events and highlight the potential role of antiplatelet therapy in this disease. The last article I want to share with you before we switch to our interview is titled Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification. The first authors are Malgorzata Furmanik and Martijn Chatrou. And the corresponding author is Leon Schurgers from Maastricht University in The Netherlands. Vascular calcification is an active process regulated by several mechanisms, including vascular smooth muscle cell apoptosis, osteochondral genic transdifferentiation, extracellular vesicle release, and cellular senescence. In healthy adult arteries, smooth muscle cells maintain a contractile phenotype. However, various insults such as oxidative or mechanical stress, can induce smooth muscle cells to lose their contractility and this process of de-differentiation is termed phenotypic switching. And phenotypic switching is thought to precede the development of vascular disease. Patients with conditions such as chronic kidney disease have mineral imbalances in their circulation and also exhibit higher levels of vascular calcification. However, the mechanisms behind these observations are not well defined. This group found that extracellular calcium can enter the smooth muscle cells via extracellular vesicles and this increased cytosolic calcium concentration. Increased calcium induces expression and activity of Nox5 in NADPH oxidase. Activation of Nox5 increased production of reactive oxygen species, which in turn decreased contractile marker expression, and also promoted calcification in vitro. Intracellular calcium signaling also further enhanced extracellular vesicle secretion, and decreased extracellular vesicle uptake. This then promoted the accumulation of extracellular vesicles in the extracellular matrix, which is a mechanism that promotes calcification. Together, these data suggest that mineral imbalances, such as those seen in chronic kidney disease patients, contribute to loss of smooth muscle cell contractility, which promotes osteochondral genic transdifferentiation. For the interview portion today, I have with me Drs Andrew Murphy and Michelle Flynn from the Baker Heart and Diabetes Institute and Monash University in Melbourne Australia. And we're going to be discussing their manuscript titled Transient Intermittent Hyperglycemia Accelerates Atherosclerosis by Promoting Myelopoiesis. But really I like the running title, which is Hyperglycemic Spikes Accelerate Atherosclerosis. So thank you both very much for joining me today. Michelle Flynn: Thanks for having us. Cindy St. Hilaire: So before we start to ‘stalk a bit about what the details of this study is, could you maybe give us a little primer on what you've done that led up to this study? Andrew Murphy: Yeah, so this really was a continuation of a study that began actually when I was in my postdoc in Allan Tall lab and working with Ira Goldberg’s lab with the postdoc  Prabhakara R Nagareddy there. We've shown along with Ed Fisher’s group at NYU, that mice that had established atherosclerotic lesions that were then made diabetic, failed to have lesion regression compared to those that were non-diabetic with normalized plasma cholesterol levels. We showed that if we gave an SGLT-2 inhibitor to normalize glucose that regression then started to occur. And then we found that this was primarily driven by myelopoiesis, suddenly increased production of monocytes, which through that entered the plaque. And so from that, that was in the hyperglycemic model which is sort of a very rare patient group these days, because most people are on well-controlled glucosteroid drugs. And really the SGLT-2 inhibitors have been a game changer in that scenario. And what we were trying to do with this study was bring it into a more clinically relevant setting that might show the potential importance of glucose on a much larger population. Cindy St. Hilaire: Excellent. Maybe you could give us an introduction to the link between what's known about diabetes and cardiovascular disease and the interplay? Michelle Flynn: So diabetic and pre-diabetic patients actually account for 65% of all cardiovascular deaths, which really indicates that diabetes itself plays a major factor alongside other things like obesity and hypercholesterolemia. And so we've previously shown that hyperglycemia was actually driving atherosclerosis in a chronic hyperglycemic setting. So given that kind of vascular disease actually affects both diabetic and pre-diabetic patients, we suspected that it may not just be chronic hyperglycemia or really intense hyperglycemia that could be driving this issue. And so what we were actually looking at in this paper was how more transient levels of hyperglycemia, which actually occur quite often in both diabetic patients and pre-diabetic patients, how much this can contribute to cardiovascular disease. Andrew Murphy: I guess this link between poor glucose control and cardiovascular disease is obviously very well established. The interesting part is that HbA1c only predicts part of the risk. If you look at fasting blood glucose, again, that's only partially responsible, but if you look at postprandial or two hour glucose loads, you'll see that that is more predictive of cardiovascular events than the other two measures. And it seems to be a continuum. So even if you are a healthy or non-diabetic individual, you obviously still have those postprandial events and depending how high that goes up is thought to be a predictive of future cardiovascular outcomes. And so obviously that's worse than people with pre-diabetes and then again worse with people that have actual, full blown diabetes. Cindy St. Hilaire: And what is a transient hyperglycemic event? What would do that in maybe you and me who don't have diabetes versus someone who has diabetes or is pre-diabetic? Michelle Flynn: So essentially what we're modeling with this transient hyperglycemia is that postprandial increase in glucose after you have a meal, which in people who have impaired glucose tolerance is going to be more pronounced than in someone who has a normal glucose tolerance. Cindy St. Hilaire: Got it. And so how did you test this in the mice? Michelle Flynn: We did this by developing a novel model of transient hyperglycemia. So we used ordinary wild type mice that weren't diabetic, and we injected them with glucose intraperitoneally, which then increased blood glucose levels in the plasma after about 15 minutes up to about 15 to 20 millimolar. And then after about two hours, this decreased back down to baseline levels. So this was very similar to what you actually see in a postprandial event. And by doing this four times throughout the day, we were able to mimic what you might see in a patient who has had several meals across the day who has impaired glucose tolerance. Andrew Murphy: One other advantage with the model that we used was that we were trying to really isolate the effects of glucose. And so by injecting glucose intraperitoneally in otherwise healthy mice, it bypasses the incretin response, which we know loses efficacy, I guess, in people that are diabetic. And so we were just really mimicking acute glucose rises that would occur after a meal. And then obviously in this wild type mouse the insulin response would then kick in to clear the glucose so it really tests that glucose hypothesis. Cindy St. Hilaire: So it's really digging in deeply on the actual sugar component, not just eating in general or other aspects. So in some of your experiments, or I guess in actually most of them, you show that the injection of glucose, it increased the plaque size in these mice, but it didn't alter the cholesterol levels. So can you explain a bit what's going on there? A little bit about the mechanism you discovered and kind of specifically introducing RAGE and the S100A8 and A9 axis? Michelle Flynn: Yeah, so what we showed was that regardless of cholesterol levels, we were seeing an increase in clot plaque size, and this was actually driven by the monocytes and neutrophils which were increased in the circulation of these mice. And then these are able to infiltrate into the plaque where they promote plaque progression. And what we found was that the increase in monocytes and neutrophils was due to an increase in their production within the bone marrow. And this was in turn due to the signaling by a protein heterodimer of S100A8 and A9, which signals via the receptor RAGE in the bone marrow on the progenitors of these cells, which induces their proliferation and differentiation. And then that produces an increase in the production of those immune cells, which promote plaque progression. Cindy St. Hilaire: Interesting. So it's really independent of kind of the basic thing that everyone thinks about, or I guess as non-scientists think about, is cholesterol. The public really focus on cholesterol, but what your study's showing is there's this whole other glucose mediated immune arm to it. What else does this S100A8-A9 regulate? Andrew Murphy: So S100A8 and A9 has some intracellular roles, which may direct the development of the model itself, but really a lot of its extracellular roles and so on is promoting sterile inflammation, chemotaxis, so activation of local immune cells. And in the context of diabetes and obesity, many of other diseases, it can signal via RAGE, as Michelle said, but it can also signal by TLR4. And so it seems as though in those diseases driven mainly by glucose, such as the modeling of postprandial hyperglycemia or all kinase in general, it will signal via RAGE, but we've also shown in the setting of obesity that it will signal via TLR4 to stimulate things like interleukin 1 beta. We've also had a paper just recently in Circulation  with Prabhakara Nagareddy’s group where we've shown post myocardial infarction that prime neutrophils in the heart to eventually release IL1-beta and cause myelopoiesis in that way. Cindy St. Hilaire: Wow, so this is really kind of an early activator of a much bigger immune response, whether it's in atherosclerosis or MI or probably, I don't know, a handful other things, I guess, right? Andrew Murphy: It seems to be really important when neutrophils are involved. So in a setting of an MI, we know that they come into the heart very early and become activated and it really makes them about 40% of the cytosol proteins of the cells. So when it degranulates or lyses, they are kind of neutral, at least in the predominant protein. Cindy St. Hilaire: Okay. So this is released in NETs in NETosis then? Andrew Murphy: That's what we're sort of discovering so far. So I guess all I can say is, stay tuned, this is a story for another day. Cindy St. Hilaire: Okay. That's really interesting though. Andrew Murphy: We haven’t looked in gglucose driven events yet. Cindy St. Hilaire: Yeah and actually one of the interesting things I've learned from your study, I had known about GLUT1 and that GLUT1 was I guess the constituently active of the glucose transporters, but I didn't realize it was so high on neutrophils and that neutrophils were so dependent metabolically on glucose. Can you maybe tell a little bit more about that story? Michelle Flynn: Yes. So the neutrophil itself is actually very highly dependent on glycolysis because it doesn't actually have many mitochondria. So compared to most cells, they have very few mitochondria so they can't really rely upon the oxidative phosphorylation for their general metabolism. And so they predominantly rely on glucose coming into the cell and then being shuttled through glycolysis to generate their energy. And yeah this does seem to be predominantly due to uptake of glucose through GLUT1. Cindy St. Hilaire: And then that excess glucose, the byproduct, is reactive oxygen species and upregulation and this cascade of- Michelle Flynn: Yes, yes that's correct. Cindy St. Hilaire: Okay, great. So currently we use HbA1c as a biomarker for overall kind of glucose regulation in diabetic patients. And based on your studies and perhaps the studies of others, would neutrophil numbers or even S100A8 or A9 be a better metric to figure out where a pre-diabetic or even a healthy patient is in terms of their glucose tolerability? Michelle Flynn: Yeah. That could actually be an interesting marker to look at. Given that neutrophils and S100 are also associated with obesity and diabetes in general, and as well as the risk for cardiovascular disease. So with the progression of diabetes, you could expect that the levels of these would increase as well. Andrew Murphy: We've shown previously when we first discovered that the S100 was important in diabetes, that in the Pittsburgh study with Trevor Orchard's group, he had followed people with type one diabetes for 20 years, that those that did develop a cardiovascular event had a higher S100A8 and A9 levels and that correlated with neutrophils. And so it certainly seems to be a marker of predictive outcomes. And so those that do have poorer glycemic control will have higher neutrophils. That's well known. And so perhaps you're right that probably in combination with HbA1c or things like two hour post glucose challenges, S100A8 and A9 and perhaps neutrophil counts would also be a nice predictive measure of potential cardiovascular outcomes of that person. Cindy St. Hilaire: Wow. That'd be really great because you could then maybe kind of more fine tune and predict which patients might be more or less susceptible to cardiovascular events. Andrew Murphy: That's right. Yeah. I think one other important aspect would be if HbA1c is deemed to be relatively well under control, yet you still have a high level of S100A8 and A9, that perhaps those transient spikes are contributing. You're not picking that up in the HbA1c, which looks like the average over approximately a month. And so that could be a nice way to add value onto that score. Cindy St. Hilaire: Interesting. I didn't realize it was that stable about over a month. All right. So I'm relatively healthy. I'm not pre-diabetic, but if I eat a whole bunch of cake or a whole bunch of ice cream or drink a lot of beer, does that create un me a transient hyperglycemic event that is of the same range we're talking about and what do your findings suggest for people who are relatively healthy and things we should be aware about regarding eating habits and things like that? Andrew Murphy: Yeah. I think it's a really good question. And it's sort of hard to give you an exact answer to that right now. We need to look at that in people, model these sort of same spikes in people, but what we I guess don't know yet, even in the preclinical models is how high and how long does that glucose have to be? And I think that's one of the most important questions first. So is there a danger zone where these neutrophils start be the innate senses of hyperglycemia that start to then release S100A8 and A9 to cause these downstream events? But what our data does show is that if you're doing this, having a binge night or a binge day once a week for your life, then that's probably not going to be a great thing. Cindy St. Hilaire: Yeah. All right. So you need to figure out is one scoop of ice cream okay, but two not so great. Andrew Murphy: Maybe if it's two different flavors it'll be okay. Cindy St. Hilaire: Maybe, right? That's great. So, I mean, is there a way we could potentially therapeutically target this signaling axis or is it too ubiquitous in terms of what it regulates? Is there a way to harness what you've found potentially in the clinic? Michelle Flynn: Yeah, so there's an inhibitor of S100A8 and A9 that prevents its binding to RAGE. It's currently approved as an Orphan Drug for systemic sclerosis in both the US and the UK. And that drug itself, we tested in our preclinical mouse model, and we found that it was in fact able to prevent their production of these immune cells, as well as prevent the accelerated atherosclerosis in response to these transient hypoglycemic spikes. Andrew Murphy: So another sort of line of thinking that we're exploring is that we could actually target neutrophil metabolism itself. And so now we're sort of understanding, are there certain proteins that are more abundantly expressed in neutrophils and not other cells in the body that would regulate glycolysis? I know that might sound a bit of a pie in the sky sort of idea, because glycolytic pathway's quite regulated, but there we have found some proteins that are rich in neutrophils and not other cells that may be responsible for the early steps of glycolysis. And so whether that can be harnessed or not, we'll have to see in the future, but it might be a way of more directly targeting neutrophils rather than approaching that's important in sterile inflammation. Cindy St. Hilaire: That makes sense. That is such a cool idea and this is really such a beautiful story. It's one of those papers that you just read it and it's just such a logical progression, but it's also really interesting and I really appreciated all those bone marrow transplants. I did those in grad school, so well done. It's a beautiful story. And then I'm just really happy that you published it with us. So thank you so much for joining me today. Andrew Murphy: Yeah thanks for having us. Michelle Flynn: Thank you. Cindy St. Hilaire: That's it for highlights from the late August and early September issues of Circulation Research. Thank you so much for listening. Please check out the Circulation Research Facebook page and follow us on Twitter and Instagram with the handle @CircRes and #DiscoverCircRes. Thank you to our guests, Drs Andrew Murphy and Michelle Flynn. This podcast is produced by Rebecca McTavish and Ashara Ratnayaka, edited by Melissa Stoner, and supported by the Editorial Team of Circulation Research. Some of the copy text for the highlighted articles is provided by Ruth Williams. I'm your host, Dr Cindy St. Hilaire, and this is Discover CircRes, your on-the-go source for the most exciting discoveries in basic cardiovascular research.  

Join our fully interactive Q&A sessions hosted by a different business expert every day. Pick up valuable tips and advice and discover practical positive steps you can take in the weeks ahead. You ask all the questions — add yours in the comments section of YouTube or Facebook or use the #QBATE hashtag on Twitter. Michelle is a Certified International Health Coach (CIHC), an Integrative Nutrition Health Coach (INHC) and Mental Health First Aider. Michelle works with individuals and companies to help them understand their health and happiness goals (e.g. healthy diet, weight loss, reducing stress, increasing exercise, better quality of sleep, improved relationships and exciting careers), and then support them as they put in place the habits to achieve and sustain them through 1-2-1 health coaching sessions, group meet-ups, presentations, workshops and company health & well-being programmes. #QuickBooks The world's largest workforce works for themselves. We work for them by providing smarter business tools. QuickBooks is always backing you. https://quickbooks.intuit.com/uk/ Subscribe to our YouTube channel: https://bit.ly/2ycNB3g Follow us on Facebook: https://www.facebook.com/QuickBooksUK/ Follow us on Twitter: https://twitter.com/QuickBooksUK Follow us on Instagram: https://www.instagram.com/quickbooksuk/

On this episode I'm joined by Michelle Flynn, from Michelle Flynn Coaching. She has a vast background in recruitment, working at the infamous SThree group at Computer Futures. Today, she works as a coach - after her own difficult experiences when it came to mental and physical health in the workplace. This is a slightly different episode, but within it there's a ton of key takeaways and points that I think will resonate with many listeners of the podcast. We chat on this episode about stress, diet and exercise, as well as being able to talk openly about mental health, too. For the junior consultants out there, this is an excellent podcast to educate yourself on burnout and how to communicate your stresses within the workplace. You can connect with Michelle on LinkedIn: https://www.linkedin.com/in/michelleflynn/ (https://www.linkedin.com/in/michelleflynn/) Timestamps SThree [1:53] What made the ingredients of their culture? [4:46] Mental health during your twenties [6:13] Diet and exercise [10:30] Health and wellbeing [14:35] Working with a health coach [17:50] Relationship with stress and how it impacts the body [20:30] What should our relationship be like with stress? [25:38] Rock bottom and how to prevent it [28:49] The value of exercise [33:52] Breathing [35:39] Calm list [37:52] Advice so people can cope better with mental challenges [39:26] How can people communicate openly in the workplace? [43:59] Parting words of advice [48:12] I hope you enjoyed the episode, the best place to connect with me is on Linkedin - https://www.linkedin.com/in/hishemazzouz/ (https://www.linkedin.com/in/hishemazzouz/) If you would love me to cover certain topics with future guests please drop me a message.  Finally, if you have been enjoying the podcast and you have two minutes then it would be greatly appreciated if you could leave a review.  Simply it will enable me to reach more people with the podcast, you can easily leave a review with the following link - https://ratethispodcast.com/rollercoaster (https://ratethispodcast.com/rollercoaster)

Join our fully interactive Q&A sessions hosted by a different business expert every day. Pick up valuable tips and advice and discover practical positive steps you can take in the weeks ahead. You ask all the questions — add yours in the comments section of YouTube or Facebook or use the #QBATE hashtag on Twitter. Michelle is a Certified International Health Coach (CIHC), an Integrative Nutrition Health Coach (INHC) and Mental Health First Aider. Michelle works with individuals and companies to help them understand their health and happiness goals (e.g. healthy diet, weight loss, reducing stress, increasing exercise, better quality of sleep, improved relationships and exciting careers), and then support them as they put in place the habits to achieve and sustain them through 1-2-1 health coaching sessions, group meet-ups, presentations, workshops and company health & well-being programmes. #QuickBooks The world's largest workforce works for themselves. We work for them by providing smarter business tools. QuickBooks is always backing you. https://quickbooks.intuit.com/uk/ Subscribe to our YouTube channel: https://bit.ly/2ycNB3g Follow us on Facebook: https://www.facebook.com/QuickBooksUK/ Follow us on Twitter: https://twitter.com/QuickBooksUK Follow us on Instagram: https://www.instagram.com/quickbooksuk/

You can watch the video replay here - https://youtu.be/dIUbrANGq5E (Video Replay) I was joined by Rhonda D'Ambrosio, Emma Dredge, Michelle Flynn & Katie Maycock. I'm so excited to bring this LIVE podcast to you all on a very important week #Mentalhealthawarenessweek We always discuss the importance of cultivating the right mindset on The Recruitment Rollercoaster Podcast to give you the best possible chance of achieving success in your recruitment career. I wanted to bring the best people I have met and spoken to about mental health in recruitment to join forces to deliver tremendous amounts of value for all of you! We're going to have an open, honest chat about a vital topic, Mental Health. The panel will share the common mental challenges they hear from recruiters. The panel will share practical advice that will leave you equipped with better tools to deal with the challenges you face mentally now & in the future. The panel will answer your questions, and we will be finishing off this LIVE podcast in a way we have never done before with a group meditation!

Leading a school is a lot to manage under normal circumstances, but what does it look like during a pandemic?Today on the podcast we’re joined by Tom Marshall, principal and lead learner from Paramus, New Jersey, and author of Reclaiming the Principalship: Instructional Leadership Strategies to Engage Your School Community and Focus on Learning.On today’s episode, Heinemann colleague Michelle Flynn talks with Tom about the challenges of leading a school through uncharted territory, how other leaders can support teachers, kids, and families, and what lessons we might learn though this process.

Everyday Rockstar (0:00:00) Lisa and Richie talk with this week's featured Everyday Rockstar. You or someone you love can be featured on the show too! Send your Everyday Rockstar nominations to thelisashow@byu.edu and put “Everyday Rockstar” in the subject line.    Giant Asian Hornets (0:06:21) Does everyone have a beekeeping suit handy? If a global pandemic wasn't enough for us, a species of giant hornets has made its way to the United States. These insects are called “Murder Hornets” or the “Asian Giant Hornets” and were spotted in Washington State. Before recently, these hornets typically only resided in certain parts of Asia. With stingers strong enough to incapacitate a human, people have taken to social media to express their terror. But with all the panic surrounding the hornets, do we really need to be as worried about them as we are? To find out we invited Sven-Erik Spichiger, managing entomologist for the Washington State Department of Agriculture, on the show today to help us dispel some rumors about the Asian giant hornets.    Going to the Chiropractor (0:21:39) The chiropractor can seem really scary. They just go in and crack your whole body. You're scared they might paralyze you. You might be scared of having to go back for the rest of your life. But, the myths just aren't true. Whether you suffer from simple back aches or you broke your leg a few years back, visiting the chiropractor may be necessary. Doctor Thomas Bithell is a licensed chiropractor in Castle Rock, CO. He owns his own clinic and has been practicing for over 20 years. He's here with us today to tell us all we need to know about going to the chiropractor.     Family Dinner Hacks (0:33:14) We all love the idea of sitting down at the dinner table as a family, having a beautiful, healthy meal and a great conversation about everyone's day. But somehow it never goes as smoothly as planned. Either the dinner takes twice as long to make or everyone's in a bad mood and doesn't want to talk. So how can we make sure our family dinner goes according to plan? Kip Deem and Chantele Gray from FreshFill are joining us today to share their top hacks to help our dinners go more smoothly. FreshFill was started to help families connect over dinner in the easiest way possible.    Helping the Homeless (0:50:36) With COVID restrictions starting to loosen up in our home state, we're feeling pretty relived. But for those less fortunate—relief from the pandemic will require more than just getting to leave the house. Across the nation, we're seeing that poor and homeless populations have been the hardest hit by COVID. So, our question is—how can we help? Here to share some ideas with us is Michelle Flynn, Executive Director of the Road Home Shelter.    Being a Good Listener (1:07:05) We've all been listening to other people a lot lately –over the phone and at home. While many of us would prefer to go back to the normality of in-person conversations with those outside of our homes, we really can't change what's happening. So what if we took this time we're spending listening to others and figured out how to be better listeners? Dr. John Grohol is a psychologist and expert in human behavior. We thought he would be the perfect person to talk to about how we can become better listeners, so we invited him on the show.    When to Give In (1:25:15) Remember the days when your toddler would fight you for two hours over getting in the bath? And now, further down the road, you're reminiscing on the bathtub days as your 16-year-oldbegsyou for the car after you've already told them “no” three times. Good times. I don't know why, but as parents, we feel the need to be 100% consistent with our kids and our rules. Now consistency is a good thing, but we can also be really hard on ourselves when we quote unquote “give in” to our kids' demands. Today, we have Dr. Rebecca Schrag Hershberg, founder of Little House Calls Psychological Services, to explain why we feel this way as parents, and how it is okay to sometimes give in. 

Lisa and Richie feature this week's Everyday Rockstar, Sven-Erik Spichiger talks about giant hornets, Thomas Bithell gives tips for going to a chiropractor, Kip Deem and Chantele Gray discusses family dinners, Michelle Flynn explains how to help the homeless, John Grohol gives listening tips, Rebecca Schrag Hershberg discusses better parenting.

Sleep. Eat vegetables. Breathe. Three simple tips from Michelle as we go off on a tangent from usual proceedings to address the challenges that many people are feeling whilst stuck at home. We focus on how the, erm, unique personalities of marketers mean that some challenges may be trickier to deal with than others and explore the importance of affirmation, perceived regression and dealing with imposter syndrome. This is a highly practical episode that I hope the marketing community (and others) get a huge amount from. Enjoy. Clink of beer glasses to the team at Paiger for their continued support of The Lonely Marketer.

On this episode, we sat down with the amazing Michelle Flynn to hear her story about stress, burnout and how it impacted her personally. Now, she's a health coach working alongside many businesses and she gave some practical tips to dealing with stress and burnout in and outside of the workplace.We spoke about:Her personal journey and how stress started to shut down her body.What she's done to overcome the burnout, and how she's transformed her life and health.Her role in helping businesses prevent employee sickness and increase productivity.The difference in coaching and therapyWhy getting to the 'root cause' is far better than treating the symptomsThe power of breathing to deal with stress and anxietyWe're very grateful for Michelle taking her time out and sharing so honestly, do let us know what you think by leaving a rating and review.To find out more, connect with her on Linkedin: https://www.linkedin.com/in/michelleflynn/To find out more about how we can help your business normalise mental health conversations, visit: http://www.everymindatwork.com Hosted on Acast. See acast.com/privacy for more information.

This is a transcript of episode 101 of our podcast Oral Surgery Admin's Time Out Podcast: Practice Management Success Tips, which you can listen to below or find wherever you listen to podcasts. If you enjoy it, please leave a 5-star review. Host Audra and Guest Linden discuss how the Society of OMS Administrators rebranded from JAWS Society to Society of OMS Administrators and how the new logo, including the honeycomb icon, was selected. [ticking clock intro] [Host Audra Lansdown] Welcome to the Oral Surgery Admin’s Time Out Podcast, for Practice Management Success Tips. This podcast is brought to you by the Society of OMS Administrators. [energetic break music] [AL] Welcome! We hope you are having an excellent day and we are glad you have joined us for one of our FIRST podcasts for our Society of OMS Administrators or SOMSA for short.  It is only fitting that we take our first time-out on this podcast journey with a little background and details on how SOMSA came to be and where we hope to take our organization. [energetic break music] [AL] Let’s start with introductions for all of our listeners. My name is Audra Lansdown and I’m from College Station, Texas.  I’ve been with Brazos Valley Oral & Maxillofacial Surgery for over 15 years and joined SOMSA in 2015. Currently, I serve as the Vice-President for SOMSA and I also serve on our education committee! I have the pleasure to host with us today, Linden Mueller, our executive director.  Linden, can you please tell us a little about yourself. [Co-host Linden Mueller] Sure! I’ve been in association management for over 7 years now, and about 6 and half of those have been with SOMSA. Before finding this career, which I really enjoy, I taught university composition and English as a Second Language composition courses to non-native speakers at my alma mater here in Springfield, Missouri, and English as a Foreign Language, grammar and other language acquisition courses at University of Giessen in Germany. [AL]I guess we want to pull all of our listeners in today and kind of explain a little bit that we’ve recently we have gone through a re-branding campaign.  Formerly known as JAWS, SOMSA was created to reach more Oral & Maxillofacial administrators. This was a difficult decision but ultimately we had exhausted all of our organic resources to expand our membership. The board felt it was necessary to join with a marketing company to help soar to the next level with our membership and our resources. Linden, you were involved in that process. Can you kind of explain a little bit on why we chose to rebrand? [LM] Yeah, the JAWS name is really meaningful. It’s an acronym for “Joining Administrators With Support,” and it relates directly to the field of work our members are in, which is really great. Our early logo even stylized the J in JAWS to look like the mandible bones. But it’s too opaque. Potential members and their doctors couldn’t tell exactly what our organization was about from our name, and that really became an obstacle for growth. And we were often confused with that shark movie! [both laugh] [AL] Good reminder! Linden, I know we went through a campaign to choose, and we ultimately went with a company to choose GPM to become our partner. Can you explain that process and how we became connected with them? [LM] Yeah, of course, this is such a great story. The Marketing Committee, led by Chair Courtney Schneider of Amarillo Oral Surgery, solicited requests for proposal from several marketing companies, and we heard four pitches last year. It was a difficult decision, but the Marketing Committee recommended Golden Proportions Marketing to the board, and the board accepted the committee’s recommendation. GPM is a full-service marketing company specializing in dental practices, so they are familiar with our industry, and they’ve worked with organizations like ours before. They did some market research for the pitch, and that really impressed the committee and that really made them stand ahead of the other three pitches that we heard. [AL] I agree, I agree. It was one very nice proposal that the put in front of us. Can you go into how you all went through and chose the logo? [LM] Well It all started with Courtney and me running a speed-dating style slide show for the Marketing Committee members with logos that GPM had created in the past to help the committee figure out what direction we wanted to go in. The styles and things like that. Then, GPM’s design team presented 8 concepts from our feedback, and from that first round, the committee had narrowed it down to 2 basic designs, the rope design and the honeycomb design is kind of how we talked about it. From there, we went through weekly reviews and we were presented with 8 concepts each time, and we quickly narrowed down from those two main icons, we really focused in on that honeycomb design. While the committee appreciated the symbolism of the rope tying members across the country together, the symbolism of the honeycomb is a lot richer, and it really resonated a lot more deeply with the committee. This whole time we were working only in black and white, so everything we saw was always in black and white. And we continued on the next few rounds in black and white and we started considering different fonts and different layouts and where does the icon go in relation to the words? Where should the line breaks in the words go? We really labored over every aspect of the logo! It was actually a really fun process. Our account manager Bess facilitated each voice to be heard and then conveyed that information back to the designer for the next round of designs. In the last 3 rounds, they finally brought in color, and that’s when we started talking about the pairings of the color and richness of the symbolism behind various combinations and the shades. And then in the very last round, we had settled on orange and blue, and we saw shades of orange and shades of blues and and different combinations of those different shades. This incremental process was such a fascinating journey to be a part of. I loved seeing the committee members negotiate their feelings about the Society and what it means to them and what they wanted the logo to convey to the outside world through color and font and symbol choices, and then finally agree on a final design. If it’s okay, I’d like to take a minute to thank everyone who was a part of this process: Michelle Flynn, Ashley Kraussman, Tara Comer, Jill Dunnam, David Nye, and Courtney Schneider who were all part of that Marketing Committee process. We had a final meeting with the board, so I’d also like to thank Keith Miller, Lynn Howard, and you, and Robin Zenz and the late Dana Leach, who were able to join Courtney, Bess, and me on that last minute call so that we could finalize the logo in time to create some promotional items to send off to our booth at AAOMS. Finally I’d like to thank Bess and Brett at Golden Proportions, who patiently guided all of the various voices and opinions along this journey. [AL] Wow! What a journey! I’m sure our members can now really appreciate the time and consideration that went into this process. It was not an easy or quick process from you’re recounting. In one of our board calls, I was very impressed with your deep tie to the symbolism of the Honeycomb and since then have connected more and more with the simple hexagon. It’s a representation of far more than just a simple glance. Linden, if you don't' mind, do you think you can recapture your conversation that you had previously had with us on that call and share more about what that honeycomb meaning is for, not only you, but kind of your outlook on what guided you through this process. [LM] Yeah, sure! It really all starts with the shape. The honeycomb is one of the strongest shapes in nature. It supports that very structure that the bees live and thrive in, and it’s actually a very efficient use of space and building materials. There’s a lot of science behind how the bees create that and how they don’t have to expend a lot of energy to create this very supportive structure for them to store their honey and plant their eggs. That’s not quite the right word, but they create their very home and their whole environment with the very basic building block of this honeycomb, hexagon shape that’s very strong. When you put all those honeycombs together, you get the beehive, and I love the, um, I’m not a practice administrator, I’m an association manager, but I hear a lot about what’s going on in your practices, and I definitely see a parallel between a beehive and an OMS practice. And so I love the symbolism of this honeycomb and the hive for what we do, what our organization is here to provide. The bees here in their hive all serve a different function, but they’re all working in concert, they’re supporting each other. If every bee is doing their job, that hive works together to produce something, the most visible to us, is something that is really sweet. It’s also healthy, it goes out into the world and makes things better for humans. But also as the bees are working, they spread pollen that allows things to grow and thrive. And without the bees doing that work, then we wouldn't have flowers and fruits and trees blooming. The closed shape of the hive symbolizes the togetherness of--and the honeycomb too--symbolizes the togetherness that our organization has and continually seeks to foster within our members. Even though we’re spread out throughout the country, we have this forum that is a beautiful way that we continue to network and educate throughout the year even though we can’t physically be together. And also something we’re trying to seek to help our members build within their practice through tools that we’re working to provide. So we want that togetherness to be present in our members’ practices as well. The honeycomb connects us to some of the aspects of what bees are known for. They are industrious and they work together. A lot of cooperation is tied into that. And so there is so much in that symbol that I think our members and our organization can draw from to really connect with and find meaning in that the Marketing Committee, like I said, the symbolism there is a lot deeper than some of the other symbols that we considered. That symbolism is something the Marketing Committee really connected with and just really love about that symbol and hope that we can continue to develop and grow in our organization. Maybe not explicitly, but implicitly through all the services and programs that we’re providing. [AL] Excellent, Thank you very much! Your passion is just wonderful to listen too! Ultimately, it’s what finalized our design and launch of our new brand and image. It’s just unbelievable the background. It just sets apart and kind of just ingrains more meaning with our members as well. Furthermore, I think that this has ultimately led the board to kind of start this process of planning for our next strategic meeting to develop the six sides of the honeycomb to represent major areas or strengths required of Practice Administrators that SOMSA speaks to. I’m very excited with our assignment and cannot wait to collaborate with our leaders! I know our team is ultimately always looking for ways to improve or network our members at a different level and this is just what really sets our society apart, especially from an administrative support system. [AL] Linden, Thank you for joining us today. [LM] Yeah, you’re welcome! [energetic break music] We hope you all have enjoyed learning more about how SOMSA was born and the image behind the name.  We are looking forward to more Oral Surgery Admin’s Time Out episodes with SOMSA. In the meantime, if you are looking to join SOMSA or you’re already a member, you can connect with us online at www.SOMSA.org, where all our member resources are hosted.  Logged in members have access to the webinar library, educational content, our forum and much more. You can also connect with us on Facebook by searching for Society of OMS Administrators or on Twitter at @somsa_omsadmin. Thank you for joining us and watch for our next episode, a 2019 conference preview in historic Savannah, Georgia, with Conference Chair David Nye. [energetic break music] We hope you have enjoyed this Oral Surgery Time Out podcast brought to you by SOMSA. If you have a Practice Management Success Tip for this podcast, please share by sending it over to the SOMSA office. We look forward to your insight. Thank you! Our intro sound is Ticking Clock Sound recorded by KevanGC shared under the Public Domain. The other sound you hear in our podcast is Tropic of Cancer 1 by Creative Commons from SoundCloud. It's a Attribution-NonCommercial 3.0 Unported license (CC BY-NC 3.0). You can find more information about the license here https://creativecommons.org/licenses/by-nc/3.0/#.

Welcome back listeners! This week we are discussing our trip to Adelaide for Sexpo Australia. We address the fun and the major problems that Sexpo Australia has to offer. We then talk about going to a BDSM party, that we got invited to, called Switch. Lastly we chat VR Porn. We were lucky enough to get to meet and interview Michelle Flynn the brains and talent behind Lightsouthern, Australia. Links from the show are:Lightsouthern: https://lightsouthern.com/Peer Rope Adelaide: https://www.peerropeadelaide.com/Switch SA: https://www.facebook.com/SwitchSA/Furniture Seduction: https://www.facebook.com/Furnitureseduction/ So go grab a drink! Then, sit back, enjoy, and as always, thank you for listening! Find us on social media!!!On Twitter @BytheBiPodcastOn Facebook BytheBiPodcastOn Instagram @BytheBiPodcastOr email us hereCheck out our OnlyFans page hereWant to help us out? Sure you do!!! Leave some feedback for us on whatever medium you listen to your podcasts on.On iTunes you can do it anonymously:– Start iTunes– Click on the menu ‘Account -> View My Account’– Look for ‘Settings -> Nickname’– Click on ‘Edit Nickname’– Set the Nickname you would like– Click ‘Submit’ See acast.com/privacy for privacy and opt-out information.

Online Porn producer & director Michelle Flynn and Adult Performer Lucie Bee talk about the push to make ethical adult entertainment and how technology has been changed by erotic content and how porn is changing with new digital innovations like VR and more.

Raised in the home of a Pittsburgh entrepreneur, Michelle Flynn developed an interest for new creative development leading her to burghTV – Pittsburgh’s Snapchat Story and 2017 Winner of Pittsburgh's PR Disruptor of the Year. She uses her training as a professional theatre and film actress to host the channel showing off Pittsburgh's hidden gems. When not snapping for burghTV, Michelle can be found chatting with her fellow sales and marketing co-workers at Truefit – a Pittsburgh-based software product innovation firm.   Prior to her involvement with Truefit, Michelle served as a student liaison for Kent State University (her alma mater) surpassing record quotas for reconnecting alumni to the University and leading to increased alumni involvement and donorship. A proud member of the National Society of Leadership and Success, Michelle continues to work in the hopes of sharing her story with this professional organization   Michelle’s Challenge; Do something different, outside your comfort zone, like an acting class.   http://www.goingdeepwithaaron.com/podcast   Connect with Michelle Instagram Twitter Snapchat   BurghTv Snapchat If you liked this interview, check out episode 88 with Sunny Lennarduzzi where we discuss Snapchat, YouTube and being your own boss.

Michelle Flynn is an actress and the host of BurghTV, a Snapchat story based in Pittsburgh, Pennsylvania. You can find her on Twitter and Instagram @burghtv and at burghtv.com.

July 11, 2016 #YaJagoffPodcast / Episode #029 Back in the studio talking about setting up fireworks on the barges, the new Pittsburgh SnapChat Channel and a tape measure app for every DIY’er except for John because he’s no DIY’er! Then, everyone fesses up about losing car or house keys! LISTEN to the Podcast show right here below or on iTunes, Soundcloud, Google Play Music and TuneIn via “Pittsburgh Podcast Network” Episode 29 Line-up: “Fireworks, SnapChat and Tape Measure Robotics” Episode Music: Memphis Hill “Blues E in D” 00:56 We are back in the studio. John almost didn’t make it because he couldn’t find his car keys so that becomes the theme for today. And, don’t forget about the Porch Tour presented by the Port Authority. 05:10 Tasha from The Food Tasters has a great “lost keys” story. Thankfully she doesn’t hate John or Craig for it! She brought us some “Maffle” breakfast sandwiches, chocolate chip muffins and gourmet granola from GetMoMuffins There’s an ice cream boat in Pittsburgh thanks to Sugar and Spice Ice Cream Parlor! Picklesburgh 2 is happening. 16:00 This is soooo cool! Brad Kriel, Founder and CEO of a Pittsburgh Company, Velocity Robotics, has created an app that syncs with a blue-tooth tape measure! It takes the pencil out of your ear! “e-Tape Construction App.” 10:25 Bobby Mays, Pyrotecnico FX from New Castle, PA, from the fireworks barge in the West End, as he’s setting up for the 2nd of 3 shows at the Pittsburgh Point. What’s HIS life like setting up fireworks? 35:40 Pittsburgh’s first official “reporter” and SnapChat news channel, Michelle Flynn of BurghTV on SnapChat. A new way to get the cool stories about Pittsburgh. Follow her on SnapChat: BurghTV. 50:53 The Porch Tour, Presented by the Port Authority starts this Saturday, July 16th at a home in Bethel Park. Our guests will be Rick Sebak and Douglas Derda of YinzLoveBBQ.com Anthony’s Coal Fired Pizza – Tasha was able to get out to an event, finally, without John and Craig and she thoroughly enjoyed it. And, The Food Tasters are hosting a gift card giveaway this week for Anthony’s Coal Fired Pizza… enter HERE! YaJagoff.com was voted Best Pittsburgh Blog via the Pittsburgh Magazine Reader’s Poll, 2016. Thanks yinz guys! Find daily #Jagoffs posts at www.YaJagoff.com How to Listen Regularly: – All shows on the “Pittsburgh Podcast Network” are free and available to listen 24/7 On-Demand in your hand on smartphone and tablet and on your laptop and desktop. – Apple users can find it on the iTunes Podcast app or player. – Android users can find it on the SoundCloud, Google Play Music or TuneIn website or app. * SEARCH: Pittsburgh Podcast Network • iTunes • Google Play Music • SoundCloud • tunein VIEW: Episode Photo Album https://goo.gl/photos/RA44rLtNffyXD34w7 Thanks, To: Photo Credits: The Food Tasters The Pittsburgh Podcast Network Production: Frank Murgia and Wayne Weil How to Follow Everyone on Twitter: The Podcast @YaJagoffPodcast John Chamberlin @YaJagoff Craig Tumas @CraigTumas John Knight @JKnight841 Memphis Hill Band @Memphis_Hill Get Mo Muffins @GetMoMuffins Picklesburgh @Picklesburgh412 Pittsburgh Downtown Partnership @DowntownPitt Sugar & Spice Ice Cream Parlor @51SugarAndSpice Sugar & Spice Ice Cream Truck @SSIceCreamTruck Sugar & Spice Ice Cream Boat @SSIceCreamBoat Velocity Robotics @VelocityRobotic Pyrotecnico @Pyrotecnico Michelle Flynn @FlynnFootage BurghTV @BurghTV Anthony’s Coal Fired Pizza @AnthonysCFPizza The Food Tasters @TheFoodTasters Follow us on Snapchat: Search: PghPodcast and YaJagoffPodcast Produced at talent network, inc. @talentnetworktv by the Pittsburgh Podcast Network @pghpodcast