Podcasts about engrams

Welcome to Episode 100 of The Stories Collective!

Check out and purchase my individual health protocols here >> [include file=get-in-itunes.html] As always we had yet another fascinating conversation with Atom Bergstrom, author of Yes, No, Maybe: Chronobiotic Nutrition. Atom Bergstrom never ceases to amaze us with his truly unique knowledge that you’re not going to be anywhere else. His information is truly fascinating. […]

Hour 1: Mike details an idea of would we be satisfied if Dalton Kincaid's rookie season was similar to Evan Engram's rookie year.

Spoken Views Radio with MC Griffin and the Poet Laureate for the City of Reno, Dustin Howard. Airing on KWNK 97.7FM every other Sunday at 5pm! Dustin Howard is a professional grant writer with a decade of dedication to non-profit organizations, especially those that serve homeless and at-risk youth. He is the author of Engrams, a collection of poetry, and a supernatural thriller novel, Breakvale. Dustin likes to fill his time with arts and crafts, amateur carpentry, and watching Star Trek when he isn't writing. A native of the Ozarks, Dustin moved to Nevada after falling in love with the mountains and the wonderful people of Reno. You can learn more about his works and connect with him on social media by visiting his website at www.dthbooks.com. Learn more about Dustin Howard and the position of Reno Poet Laureate, HERE

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.03.17.533126v1?rss=1 Authors: Autore, L., O'Leary, J., Ortega-de San Luis, C., Ryan, T. Abstract: Long-term memories are stored as stable configurations of neuronal ensembles, termed engrams. While investigation of engram cell properties and functionality in memory recall has been extensive, less is known about how engram cells are affected by forgetting. We describe a form of interference-based forgetting using an object memory behavioral paradigm. By using activity-dependent cell labelling, we show that although retroactive interference results in decreased engram cell reactivation during recall trials, optogenetic stimulation of the labelled engram cells is sufficient to induce memory retrieval. Forgotten engrams may also be reinstated via the presentation of similar or related environmental information. Furthermore, we demonstrate that engram activity is necessary for interference to occur. Taken together, these findings indicate that retroactive interference modulates engram expression in a manner that is both reversible and updatable. Retroactive inference may constitute a form of adaptive forgetting, where in everyday life new perceptual and environmental inputs modulate the natural forgetting process. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.02.24.529744v1?rss=1 Authors: Dorst, K. E., Senne, R. A., Diep, A. H., de Boer, A. R., Suthard, R. L., Leblanch, H., Ruesch, E. A., Skelton, S., McKissick, O. P., Bladon, J. H., Ramirez, S. Abstract: Memory engrams are both necessary and sufficient to mediate behavioral outputs. Defensive behaviors such as freezing and avoidance are commonly examined during hippocampal-mediated fear engram reactivation, yet how reactivation of these cellular populations across different contexts engages the brain to produce a variety of defensive behaviors is relatively unclear. To address this, we first optogenetically reactivated a tagged fear engram in the dentate gyrus (DG) subregion of the hippocampus across three distinct contexts. We found that there were differential amounts of light-induced freezing depending on the size of the context in which reactivation occurred: mice demonstrated robust light-induced freezing in the most spatially restricted of the three contexts but not in the largest. We then utilized graph theoretical analyses to identify brain-wide alterations in cFos co-activation during engram reactivation across the smallest and largest contexts. Our manipulations conferred greater positive cFos correlations and recruited regions spanning putative fear and defense systems as hubs in the respective networks. Moreover, reactivating DG-mediated engrams generated network topologies across experimental conditions, emphasizing both shared and distinct features. By identifying and manipulating the circuits supporting memory function, as well as their corresponding brain-wide activity patterns, it is thereby possible to resolve systems-level biological mechanisms mediating memory's capacity to modulate behavioral states. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC

This week, Josh and Corey discuss the focused engram changes and the economy, what they expect to stay and change over the course of the year, and answer listener questions. Join the Tower Casuals Discord! Email Us: towercasuals@gmail.com Follow Tower Casuals: Twitter | Instagram | YouTube | Twitch Follow Corey: Twitter | Instagram Follow Josh: Twitter | Twitch You can find Tower Casuals: The Destiny Podcast on YouTube and your podcast service of choice every Friday night. Remember if you're watching on YouTube to follow the channel. If you're listening on Apple Podcasts or Spotify, leave us a review and five star rating. Thanks for listening!

--{ ""WAR IS PEACE FREEDOM IS SLAVERY IGNORANCE IS STRENGTH" - George Orwell, "1984" Hour 1 "}-- Worldwide Martial Law, Identification, Monitoring - Dream of Tyrants has Materialized - No Personal Privacy - Being "Anti-Social" and Having "Something to Hide" - MI6, CIA, Supergovernment - Indoctrination, Perpetual Education - One-Eyed Monster - TV Newscasters - Arthur Koestler's "Ghost in the Machine" book - Council on Foreign Relations - Property Taxation - Border and Airport Search and Seizure of Cell Phones - Computers, Electronic Devices - US Customs, Racial Profiling - Surveillance Cameras in Your Home - Big Brother of George Orwell - Mercury in Vaccines - Faith in Medicine - Early Children's Inoculations, Fevers, Inflammation - Virtual Reality, Interfacing, Engrams, Programming - Pentagon's "Virtual World". Data Collection, Individual "Nodes", Simulations, Predictability - Online "Communities" - US Department of Homeland Security, Passport as "Travel Permit", Right to Return, USA No-Fly List - Western Hemisphere Travel Initiative - Clear Pass, New Nomads, Bureaucratic Class - The Millennium, Massive Change, New Type of Society - "World Service" - Destruction of Old Normals - Huxley's "Brave New World" - Ideal Design - Francis Bacon's "New Atlantis" - Categories of Psychopathy - Politicians, Actors - Psychopathic Family Lineages.

Welcome to Cryptic Soup. Join Thena and Kylee as they start a 2 part series on Scientology! In part one they will discuss who L. Ron Hubbard, aka the creator, is and his wild life full of accomplishments, war memories, lies, slander, too many wives, and everything in between. They start the conversation about Dianetics and Engrams, to give you the foundation of Scientology, to get you ready for part two, where the cult…. Er… I mean religion really comes alive and begins thriving.

Happy Thanksgiving! We are so excited for this week's episode of The Stories Collective as we're sharing the conversation we got to have with Sharon Engram. This conversation is especially pertinent for this week as Sharon shares with Sarah about having a spirit of thanksgiving and gratitude all lifelong no matter the circumstance. So much of what we know as life at Desert Springs would not be possible without the couple and family we're talking about today. Sarah and Sharon met for coffee before recording and the question became, "how do we fit 60 years of marriage and ministry into an hour conversation?" We did our best to do that for you

YouTube link: https://youtu.be/kgMFnfB5E_A This theolocution has been released early in an ad-free audio version for TOE members at http://theoriesofeverything.org. Sponsors:  - Drink Trade: https://www.drinktrade.com/everything for 30% off - Ro Man: https://ro.co/curt for 20% off first order - Masterworks: https://www.masterworks.com/ promocode: theoriesofeverything *New* TOE Website (early access to episodes): https://theoriesofeverything.org/ Patreon: https://patreon.com/curtjaimungal Crypto: https://tinyurl.com/cryptoTOE PayPal: https://tinyurl.com/paypalTOE Twitter: https://twitter.com/TOEwithCurt Discord Invite: https://discord.com/invite/kBcnfNVwqs iTunes: https://podcasts.apple.com/ca/podcast/better-left-unsaid-with-curt-jaimungal/id1521758802 Pandora: https://pdora.co/33b9lfP Spotify: https://open.spotify.com/show/4gL14b92xAErofYQA7bU4e Subreddit r/TheoriesOfEverything: https://reddit.com/r/theoriesofeverything LINKS MENTIONED: - Michael Levin (Solo TOE podcast): https://youtu.be/Z0TNfysTazc - Michael Levin Theolocution With Chris Fields & Karl Friston: https://youtu.be/J6eJ44Jq_pw - Joscha Bach Theolocution With John Vervaeke: https://youtu.be/rK7ux_JhHM4 - Joscha Bach Theolocution With Donald Hoffman: https://youtu.be/bhSlYfVtgww - Joscha Bach (Solo TOE podcast): https://youtu.be/3MNBxfrmfmI This episode has been released early in an ad-free audio version for TOE members at http://theoriesofeverything.org/ TIMESTAMPS: 00:00:00 Introduction  00:01:55 Bach and Levin speak about each other's work 00:03:34 The cell functions as a neuron  00:07:15 Software as a control pattern 00:10:55 Disciplinary boundaries in academia 00:14:38 The perceptron is a "toy model" of the brain 00:18:44 How do you identify yourself as a researcher? 00:20:10 The benefits of podcasts vs. academia 00:30:04 Beliefs of Bach's and Levin's that have drastically changed 00:38:54 Memory moves outside the brain structure 00:45:06 Engrams and memory storage 00:47:30 The implications of transferring memory between species 00:55:25 Weissman's barrier 00:59:25 The notion of "competence" (Bach's and Levin's largest insight) 01:12:10 Virtualization for unreliable hardware 01:16:02 Defining "competence" 01:22:35 Bach's issues with goals (for and against teleology) 01:27:34 Planarian goals and explicitly encoded instructions 01:34:55 Navigation in "Morphic Space" 01:36:11 One species' birth defect can be another's benefit 01:37:42 The "Intelligence Trap" and bias 01:39:05 Application of each others' work to their own 01:52:25 Necessities of general intelligence in cells Learn more about your ad choices. Visit megaphone.fm/adchoices

You might be surprised by Dr. Power's fact about how memories are physically stored in our brains. Take a moment to listen and learn about our personal constellations.

A recording of a Jenuine Healing private session

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.08.27.505441v1?rss=1 Authors: Delamare, G., Feitosa Tome, D., Clopath, C. Abstract: Memories are thought to be stored in neural ensembles known as engrams that are specifically reactivated during memory recall. Recent studies have found that memory engrams of two events that happened close in time tend to overlap in the hippocampus and the amygdala, and these overlaps have been shown to support memory linking. It has been hypothesised that engram overlaps arise from the mechanisms that regulate memory allocation itself, involving neural excitability, but the exact process remains unclear. Indeed, most theoretical studies focus on synaptic plasticity and little is known about the role of intrinsic plasticity, which could be mediated by neural excitability and serve as a complementary mechanism for forming memory engrams. Here, we developed a rate-based recurrent neural network that includes both synaptic plasticity and neural excitability. We obtained structural and functional overlap of memory engrams for contexts that are presented close in time, consistent with experimental studies. Moreover, we showed that enhancing the initial excitability of a subset of neurons just before presenting a context biases the memory allocation to these neurons. We then explored the role of inhibition as a way of controlling competition among neurons from two ensembles. This work suggests mechanisms underlying the role of intrinsic excitability in memory allocation and linking, and yields predictions regarding the dynamics of memory engrams. Copy rights belong to original authors. Visit the link for more info Podcast created by PaperPlayer

In light of several different small details coming out about Trump's attorney, we decided to look at narrative therapy and narrative reframing. This is a therapeutic tool that can point to ways in which people get manipulated.  www.healthy-perspectives.com  

In this episode, Lexman interviews Saifedean Ammous about his new book "Peruzzi, Coif, and Karaite Engrams". They discuss the different theological schools and what their differences are. They also cover the history of karaite Judaism and the importance of engrams.

An episode of the Jen's Gems podcast series

Topic: Happy Holidaze! Festivus for the Rest of Us : ) Happy Holidays y'all!  In this episode Waska and Beth discuss the good, the bad and the ugly of the holiday season - Holiday cheer or fear?; do you stress out over the holidays? Engrams and how they can rear their ugly heads; changing our old stories that no longer serve, gift giving; sacred contracts and more. *FREE* –  Waska is offering 3 complimentary 'Healing Strategy Sessions' for the first 3 men who respond by email: waska@illuminatedwarrior.com Send a message including what area you would like help illuminating.  Learn more about Waska here: www.Illuminatedwarrior.com https://illuminatedwarrior.com/services

For our 1 year anniversary we are continuing with our journey through scientology. Have you reached clear yet?

ゲスト回を振り返ってEngramについて雑談したり、最近目にした面白い論文をフラッシュトーク的に紹介しあったりしました。(収録:4/24) Show Notes: 冒頭雑談 ( - 0:26:25) 変異株に対するワクチンの有効性 、論文 プロテアーゼを一緒に打ち込む: この論文 Nature Medicineでした マシュマロ: 誹謗中傷を自動で除外する匿名コメント機能 (4/29- 受け付けてます!) エングラム雑談 (0:26:35 - ) Sheena Josselyn: 扁桃体等をモデルに記憶を担う細胞について研究。CREB関連の仕事が有名 Richard Semon (1859-1918): 動物学者・進化生物学者。エングラムの存在を予想。 Josselyn/Tonegawaによる総まとめ的総説決定版:Memory engrams: Recalling the past and imagining the future ジフ: 最初期遺伝子の一つ、Zif-268のこと All Optical Physiology: プローブを用いて神経活動を蛍光観察しながら同視野の個々の細胞を光遺伝学的に操作する手法のこと Pattern Completion: 不完全な情報から完全な情報の神経活動パターンを再現すること シーケンシャルな入力があった時に下流が違う 例えばLosonczyのお仕事 Kellerのプレプリント:海馬CA1、V1 利根川研のValence論文 EngramのサイズはPV or SOMにコントロールされる JosselynのEngramテンポラルオーバーラップ論文 Eleven maps for eleven rooms 記録は11部屋で、CA3でした..汗　Fig1が圧巻 Roy/TonegwaのChungとコラボしたdispersed engram complex hypothesisに関するプレプリント 新企画:フラッシュ論文紹介 (1:10:05 - 2:00:13) 萩原 Gloria ChoiのSocial Distance論文 TRHはなんのこっちゃない甲状腺刺激ホルモン放出ホルモン。 ブラピのゾンビ映画: World War Z (腐トマ) 理研CBS・村山さんのFASHIO2p論文、巨大Obj w/NA0.8! Jerry Chen (+Spencer Smith)の追っかけプレプリント？要はDiesel2pのmultiplexを4にしてきた感じ。 Matt Wilson、電気生理やめるってよ (何故か1p imagingの解析論文出してきた) Grad-CAMの使い方うまい。 MouseのPFCのカテゴリー表象、マウストレーニング芸。Bonhoefferラボ。 HongのSocial Reward論文。Social rewardはgeneral rewardである。 宮脇 RABID-seq ディソる: 細胞をバラバラにする（dissociation）すること Svobodaのrabiesのcaveatに関するブログ。 Carsen & Marius, 視覚皮質で大規模イメージング、集合的活動は正確に見ている縞の角度を判別可能だが行動の結果にはかかわらない。 Lubenovラボ、Kajikawaさんによる論文。Awake Ripple時、CA3で過分極 Neuropixels 2.0、電気生理での同一細胞長期記録 Open Ephys: 電気生理関連のハードウェアやソフトウェアをオープンソースで提供 DAC: デジタル-アナログ変換回路 (あるいはData AQuisition) Editorial Notes: フラッシュトーク、一瞬で終わった気分だったんですが１時間弱やってたんですね（宮脇） これは我ながらいい新企画だと思いました。冒頭の雑談が長いので今回からchapter機能をつけてみました、一思いに飛ばしてください (萩原)

This episode is also available as a blog post: https://truthliesinreality.wordpress.com/2021/04/27/vocaloid-engrams/ --- Send in a voice message: https://anchor.fm/truthliesinreality/message

In our thrilling two hundred and forty-eighth episode Fox and Conrad continue their journey through the Galaxy’s Greatest Comic with Progs 756-759 of 2000AD, covering November 1991. This episode ABC Warriors, Robo-Hunter, and Universal Soldier reach their climaxes, Dredd fights the flab, Feral goes to war, and Judge Anderson is back to solve some Engrams! … Continue reading ep 248 – Progs 756-759

This week we were joined by a great artist, KobOneArt. First a deep dive into his gaming and art history. Then we got into the Story telling this season which has been great. Season of the Chosen Umbral Engrams, BattleGrounds and Hammer of Proving are starting to wear on us with this grind. Stasis is getting lots of changes to mostly its PvP effects, and a recap with Lord Cognito of the changes coming to Destiny 2 down the road. You can find KobOneArt here: Twitter - https://twitter.com/KobOneArt Twitch: https://www.twitch.tv/KobOneArt Ebontis Twitter: https://twitter.com/Ebontis Twitch: https://www.twitch.tv/ebontis Youtube: https://www.youtube.com/channel/UC9xJ-_kYMxVGHuL5hG3iJyg LordCognito Twitter: https://twitter.com/LordCognito Youtube: https://www.youtube.com/channel/UCYiUhEbYWiuwRuWXzKZMBxQ You can support The Last Word Podcast right here https://anchor.fm/ebontis/support --- Send in a voice message: https://anchor.fm/ebontis/message Support this podcast: https://anchor.fm/ebontis/support

Let's discuss Umbral Engrams in Destiny 2 Season of the Chosen. The HELM upgrades and the umbral recaster in Season of the Chosen is so grindy and bottlenecked that players aren't even trying to do Tier 2 and Tier 3 Umbral Engram focusing. Watch LIVE :: https://www.youtube.com/saynotorage SNTR Network :: http://sntrnetwork.com/ --- Support this podcast: https://anchor.fm/sntrpresents/support

Destiny 2 Season 13 will see Umbral Engrams returning. Bungie announced that Umbral Engrams will return to Destiny 2 in Season 13. Many are excited about this, but I'm worried about a few aspects. Watch LIVE :: http://youtube.com/saynotorage SNTR Network :: http://sntrnetwork.com/ --- Support this podcast: https://anchor.fm/sntrpresents/support

The Rageless Roundtable discusses the weekly lockout for Hawkmoon random rolls and then they get in an unplanned and spirited debate about the state of Destiny 2 and who is to blame, and they finish up with the umbral engrams returning to Destiny 2 Season 13. Watch LIVE :: https://www.youtube.com/saynotorage - SNTR Network :: http://sntrnetwork.com/ --- Support this podcast: https://anchor.fm/ragelessroundtable/support

This week we were joined by a great guest from the UK, CloudPlays. This man is a chef and content creator and we had a great chat with him. This week we discussed the full Hawkmoon quest called Harbinger, random exotic rolls and collections. Then we turned to the TWAB to discuss the future seasonal content and how it will be handled, Umbral Engrams, Gilded Titles and more. You can find CloudPlays here: Twitter - https://twitter.com/CloudPlaysYT Twitch: https://www.twitch.tv/cloudplaysd2 Youtube: https://www.youtube.com/channel/UC8D47Pv6mdRHgzIzxsy-q3w Ebontis Twitter: https://twitter.com/Ebontis Twitch: https://www.twitch.tv/ebontis Youtube: https://www.youtube.com/channel/UC9xJ-_kYMxVGHuL5hG3iJyg LordCognito Twitter: https://twitter.com/LordCognito Youtube: https://www.youtube.com/channel/UCYiUhEbYWiuwRuWXzKZMBxQ You can support The Last Word Podcast right here https://anchor.fm/ebontis/support --- Send in a voice message: https://anchor.fm/ebontis/message Support this podcast: https://anchor.fm/ebontis/support

Let's talk about Umbral Engrams, Gilded Titles, and Hawkmoon!

Ori, Jason, Erin, and Vincent dissect a study that utilizes single-cell RNA sequencing to reveal the genes that underlie remote memory storage in the medial prefrontal cortex of the mouse. Hosts: Ori Lieberman, Erin Calipari, Jason Shepherd, and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiN! Links for this episode Transcriptional programs associated with long-term memory (Nature) Timestamps by Jolene. Thanks! Music is by Ronald Jenkees Send your neuroscience questions and comments to twin@microbe.tv

“Why do we sleep?” is the first topic. “The scientists don’t really get to the nitty-gritty because they don’t look at the holistic level,” begins Patrick. He discusses Conscious Dreaming, Soul Travel, Engrams, Sleep Deprivation, and related subjects. “Why does the body age?” is the second topic. Patrick is writing a book about it. Patrick discusses the latest Trump/Biden debate. “Carbon is not a problem,” says Patrick, discussing Biden’s stance on electric vehicles. People ask questions about the AquaCure hydrogen machine. Yawning is discussed. Does the body age because we believe in time?; Patrick elaborates about how we create “time.” Atom writes in about the lungs being the pump, not the heart, according to the work of M.J. Rodermund, 120 or more years ago. Several listeners ask about teeth problems. Patrick discusses a personal experience. Atom writes in about Gilbert Ling using ouabain as one of his proofs that there’s no such thing as a sodium pump. Listeners write in about Carolyn Bormann discussing hydrogen on a previous One Radio Network show. A listener asks a question about Richard Proctor and his One Radio Network interview (Oct. 15, 2020), specifically about electoral vote certification. Patrick discusses Richard Proctor’s book, Saving the Constitution (2019). A listener writes in about nuclear energy’s role in the Great Reset. Patrick and Shawn discuss the U.S. as corporation, U.S. legal versus lawful courts, COVID as one of the biggest scams, and a variety of subjects. A listener writes in about the stomach being associated with the eyes.

Releasing past life issues that were affecting eye sight

April, Keri, Stacy, and Chris bring to a conclusion our series on Scientology. Talking about the creation of Sea Org and the reign of David Miscavige.

April, Keri, Stacy, and Chris discuss the crazy world of Scientology. Talking about its creator and the start of one of the most mysterious religious organizations in the world.

#reconsolidation #PTSD #neuroscience #learning #memory From NeuroBeer #4 - streamed live June 15, 2020. Full conversation: https://youtu.be/yhxyuBLiLs8 In order to remember something, you must have learned it first. When something new is learned, the brain stores that information through a series of electro-chemical connections between neurons, known as a memory 'engram'. These 'neural engrams' allow for the recall of memories by triggering the re-activation of the same brain connections where the memory was stored. Many prominent theories of learning and memory in neuroscience suggest that when a memory is recalled, it is subject to modification - the strength of the memory can be increased or decreased depending on how much attention is devoted to the memory once it's recalled. So is it better to learn the first time? Or does one need to re-learn the same information repeatedly throughout life to ensure it doesn't vanish from memory? We cover memory engrams, evolutionary biology of memory, bible history and potential applications of reconsolidation to PTSD treatment. We're a group of Canadian neuroscientists reviewing the latest news, events and scholarly publications from this week in neuroscience and beyond! In each NeuroDrugs live stream we review classics in the field of addiction neuroscience, as well as newly published articles on a weekly basis. open access articles: https://www.cell.com/neuron/fulltext/S0896-6273(20)30354-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0896627320303548%3Fshowall%3Dtrue & https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2680680/ Additional resources: https://www.sciencedaily.com/releases/2020/06/200604152116.htm & https://www.sciencedaily.com/releases/2020/06/200605105359.htm Join us for NeuroBeer every Monday (8pm EDT) & NeuroDrugs every Wednesday (9pm EDT) on YouTube for the largest interactive live streaming journal club & contribute to the conversation! Stay tuned to stay up to date with the latest in neuroscience / general science news! A Production of First-Person SciencePlease subscribe @ www.youtube.com/firstpersonsciencepodcast if you enjoy our content, and share it with friend and platforms that might be interested! It goes a long way in helping us stamp out misinformation in neuroscience media!  

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.07.01.182782v1?rss=1 Authors: Cincotta, C., Murawski, N. J., Grella, S. L., McKissick, O., Doucette, E., Ramirez, S. Abstract: Alcohol withdrawal directly impacts the brain's stress and memory systems, which may underlie individual susceptibility to persistent drug and alcohol-seeking behaviors. Numerous studies demonstrate that forced alcohol abstinence, which may lead to withdrawal, can impair fear-related memory processes in rodents such as extinction learning, however the underlying neural circuits mediating these impairments remain elusive. Here, we tested an optogenetic strategy aimed at mitigating fear extinction impairments in male c57BL/6 mice following exposure to alcohol (i.e., ethanol) and forced abstinence. In the first experiment, extensive behavioral extinction training in a fear-conditioned context was impaired in ethanol-exposed mice compared to controls. In the second experiment, neuronal ensembles processing a contextual fear memory in the dorsal hippocampus were tagged and optogenetically reactivated repeatedly in a distinct context in ethanol-exposed and control mice. Chronic activation of these cells resulted in a context-specific, extinction-like reduction in fear responses in both control and ethanol-exposed mice. These findings suggest that while ethanol can impair fear extinction learning, optogenetic manipulation of a fear engram is sufficient to induce an extinction-like reduction in fear responses. Copy rights belong to original authors. Visit the link for more info

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.05.28.121822v1?rss=1 Authors: Doucette, E., Leblanc, H., Monasterio, A., Cincotta, C., Grella, S. L., Logan, J., Ramirez, S. Abstract: The hippocampus processes both spatial-temporal information and emotionally salient experiences. To test the functional properties of discrete sets of cells in the dorsal dentate gyrus (dDG), we examined whether chronic optogenetic reactivation of these ensembles was sufficient to modulate social behaviors in mice. We found that chronic reactivation of dDG cells in male mice was sufficient to enhance social behaviors in a female exposure task when compared to pre-stimulation levels. However, chronic reactivation of these cells was not sufficient to modulate group differences in a separate subset of social behaviors, and multi-region analysis of neural activity did not yield detectable differences in immediate-early gene expression or neurogenesis, suggesting a dissociation between our chronic stimulation-induced behavioral effects and underlying neural responses. Together, our results demonstrate that chronic optogenetic stimulation of cells processing valent experiences enduringly and unidirectionally modulates social interactions between male and female mice. Copy rights belong to original authors. Visit the link for more info

Bungie announced new Redacted Engrams coming to Destiny 2 in Season 11. I walk through the details and talk about why this is so close to weapon boons that I'm very happy. -- Watch LIVE at https://www.twitch.tv/saynotorage --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/sntrpresents/support

This week we had cbgray join us on the podcast and got to know his history of Destiny and his journey as a content creator. We got his take on top raids and moments of the franchise as well. We discussed the TWAB for May 8th which had Luke Smith talking about changes coming in Year 4 and Season 12 and beyond. Rewards will be improving. Vanity or Cosmetics will be spread more into game activities and less in Eververse. Aspirational content will have new armor tied to the activity each year. Core activities will be getting new armor and weapons as well in Year 4 and beyond. Many good things are coming next year, and while Season 11 is nearly in motion already, the fall looks very promising. You can find cbgray at the following places: https://twitter.com/cbgray_ https://www.twitch.tv/cbgray https://www.youtube.com/cbgray You can find us here. The Last Word Twitter: https://twitter.com/LastWordPod Ebontis Twitter: https://twitter.com/Ebontis Twitch: https://www.twitch.tv/ebontis Youtube: https://www.youtube.com/channel/UC9xJ-_kYMxVGHuL5hG3iJyg LordCognito Twitter: https://twitter.com/LordCognito Youtube: https://www.youtube.com/channel/UCYiUhEbYWiuwRuWXzKZMBxQ You can support The Last Word Podcast right here -- https://anchor.fm/ebontis/support --- Send in a voice message: https://anchor.fm/ebontis/message Support this podcast: https://anchor.fm/ebontis/support

What is learning and memory? Is amnesia really a loss of stored memories or something more? In this interview, we will discuss where memory goes and if there is a way to retrieve them after trauma. Recent studies have shown that spatial memories are encoded as sparse populations of cells that are activated during learning and are necessary for the retrieval of specific memories. We refer to these cells as "memory engram cells" and the focus of Tomás J Ryan and his team is to understand how engram cells are able to store specific memories as information. Here is a quick summary/breakdown of the video above. The old storage theory of amnesia is WRONG. The problem is the ability to retrieve the memory. Short term memory lasts a few hours. It is very disruptable (long term is not). Long term memory lasts your entire lifetime. It requires transcription and translation of many different genes. We have many different genes that regulate memory. They are different for short term and long term - playing roles at different stages. Most popular was CREB (turns on other genes). Engrams cells are structures in the brain where memories are stored. R They used optigenetics to prove engram cells were important for memory. Engram cells only account for 4-6% of the brain cells in the hippocampus (of mice). V Consolidation idea - a short term memory (unstable) forms into a long term memory (stable), thus stabilizing the engram. Optogenetics - let's us express photoactivatable opsins in whatever region of the brain we want. The brain is electrically active. They put certain opsins into brain cells and then stimulate them with light. These opsins can conduct ions - putting positively charged cations from the external environment of the cell into the neuron. This depolarizes the cell, which results in an action potential (creating neuronal activity). What they did at MIT was integrate optogenetics and memory engram cells. They tested parts of the brain using a transgenetics - they took immediate/early genes (genes that show activity as a function of neuronal spike) and used opsins to only activate those genes. Amnesia and Memory Learning is the enhancement of synaptic connections. Memory is a stable thing in the brain and can last for your entire life. Learning and recall are not "things", they are activities. Learning = process of making a memory. Recall = process of retrieving a memory. So the problem is not memory itself. Amnesic engram cells have a loss of synaptic strength. Increasing the synaptic strength helps get the memory (which is commonly seen in Alzheimer's (AD), Huntington's (HD)). If you increase the synaptic potentiation (increasing the dendritic spine density), esp. of the amnesic engram cells, you can get natural access to those memories. Neurotrophic factors (BDNF, NGF, CNTF, GDNF) do this, but are not localized nor memory specific. Learning something new (about something you are amnesic about) will train your brain to those particular engram cells. Once you activate the engram cells (with optogenetics), you can restore access to old information and add new information on those amnesic memories. Without dealing with the cause, you probably won't be able to really restore memories (in diseases like AD, HD, etc.) In late stages of neurodegeneration, you may actually lose memories. Actions to take for prevention Stay mentally active Engage in physical exercise Actions to take for amnesia (acute memory loss) Do everything to remind yourself of those experiences Retrain on the "forgotten" pieces We briefly discussed gene expression and histone acetylation to enhance memory. https://mybiohack.com/blog/tomas-j-ryan-debunking-amnesia-and-stabilizing-engram-cells

Psychic Predictions 2019 Review; News Items: Virtual Humans, GM Trees, Australian Fires, Engrams, Puffin Tool Use; Who's That Noisy; Science or Fiction

Psychic Predictions 2019 Review; News Items: Virtual Humans, GM Trees, Australian Fires, Engrams, Puffin Tool Use; Who's That Noisy; Science or Fiction

Dr. Morse discusses Evan Engrams knee injury

@exroommates | exroommatespodcast@gmail.com It's time for part 2 of our Scientology series! In this episode we cover the remaining timeline up until today and the core beliefs of Scientology. Get ready for Xenu, SeaOrg, Thetans and more!

You can find us through: http://destinyaddicts.wixsite.com/destinyaddicts   destinyaddictspodcast@gmail.com      https://discord.gg/Mm85udf Our Clan Page https://www.bungie.net/en/ClanV2/Chat?groupId=1984357 Patreon https://www.patreon.com/DestinyAddictsPodcast Twitter @DestinyAddicts1

In this weeks news: Destiny 2 is released and fans are mad, Bethesda is dumb, Shadow of War is shady, games journalist bad at game, and Mario no longer a plumber?

In this weeks news: Destiny 2 is released and fans are mad, Bethesda is dumb, Shadow of War is shady, games journalist bad at game, and Mario no longer a plumber?

Destiny 2 is making big changes to engrams and how engrams decrypt, this will have a massive impact on gearing up and moves the game in a very positive direction. Destiny 2 releases today!!! Have a great time with Destiny 2 guardians we hope the beginning of this new adventure is an amazing time for you and your friends. Thanks for listening to and supporting Destiny The Show for over 3 years. We are excited to embark on this new journey with you in Destiny 2. Kick Ghaul’s butt, have fun, try to avoid spoilers, good luck in the Destiny 2 Raid, and good luck in the new Trials of the Nine!

Spoiler Alerts for this week’s show as massive leaks everywhere for Destiny 2 have surfaced. We have Raid Information, the new Prestige Difficulty, brand new Engrams and types of Engrams, 3rd subclass reveals, a boatload of new information about the European Dead Zone including new secret hidden areas. Public Event footage shows us that the hidden heroic mechanics are pretty darn cool. The Destiny 2 PC Beta goes live today and the full release of Destiny 2 on console is now just a week away. Thanks for listening guardians and have a great week!

Special Guest: Snax the Cat.

In Orbit Talks 2.4.0 Update

In this episode, Huzefa shares an amazing article from Scientific American that describes a revolutionary study that unearths the mechanism […]

News March 10, 1988 Thursday 7pm. 2 crazy fans break into Paramount and try to film a fake documentary & get caught. 3 days into writer’s strike. STID - Nominated Best Visual Effects Ten Forward: Chris Twitter: What Trek term do u think is the most widely used today by the general public? My vote is "Warp Speed". Chris Twitter: Who do u think had a bigger impact in Trek, the Borg or Q? Star Trek in pop culture: Sniper: Reloaded, 2011. U.S. Marine Sgt. Brandon Beckett takes on the toughest assignments -- including a deadly mission to rescue a Belgian plantation owner from hostilities in the Congo. In this scene, troops are going somewhere in a truck. Episode insight: Voyager: Equinox Part 2 Character insight - Silik Subspace communications Ken P.

Engrams and tracings of revelation no longer satisfy the hungry minds of the searchers of beyond the beyond. Stand on you feet and be excited you whale-of-facts-fishers.. for intrigue is in pursuit of sketching a map of speaking stars like the star that led the wise men to the Lord Christ child. Magnitudes are speaking, therefore, space junk is falling from the skies. It is a time of wire pulling, for antique ways no longer fit the wireless, space to space, and spirit to spirit, transmissions of God's new and living word. A sphere of revelation paved with sapphires of love has girted the Holy Manifest to become a spiritual diamond processing conductor where the Word of God can move God-Light from destiny to destiny and from glory to glory. Now comes the Manifester with Part 17. Let that which must tumble, tumble, and that which must fold, fold. For now must the crooked places become straight and the hills rise like mountains kissing skies. Jerry O. Lee, D.D., The Manifester Yada

Worldwide Martial Law, Identification, Monitoring - Dream of Tyrants has Materialized - No Personal Privacy - Reality Shows - Being "Anti-Social" and Having "Something to Hide". MI6, CIA, Supergovernment - For Your "Security" and "Safety" - Foundations. Indoctrination, Perpetual Education - One-Eyed Monster - TV Newscasters - Exposes. Arthur Koestler's "Ghost in the Machine" book. Council on Foreign Relations meetings, Property Taxation. Border and Airport Search and Seizure of Cell Phones, Computers, Electronic Devices - US Customs, Racial Profiling. Surveillance Cameras in Your Home, Big Brother of George Orwell. Mercury in Vaccines - Faith in Medicine - Early Children's Inoculations, Fevers, Inflammation, Lobotomy. Virtual Reality, Interfacing, Engrams, Programming - Pentagon's "Virtual World". Data Collection, Individual "Nodes", Simulations, Predictability - Online "Communities", Diaries. US Department of Homeland Security, Passport as "Travel Permit", Right to Return, USA No-Fly List - Western Hemisphere Travel Initiative - Clear Pass. New Nomads, Bureaucratic Class - The Millennium, Massive Change, New Type of Society - "World Service" - Destruction of Old Normals. Huxley's "Brave New World" - Ideal Design - Francis Bacon's "New Atlantis". Categories of Psychopathy - Politicians, Actors - Psychopathic Family Lineages. (Articles: "Britain is slithering down the road towards a police state" Simon Jenkins, The Guardian (guardian.co.uk) - Feb. 6, 2008. "Clarity Sought on Electronics Searches - U.S. Agents Seize Travelers' Devices" by Ellen Nakashima, Washington Post Staff Writer - Feb. 7, 2008 Page A01. "New travel document requirements for USA citizens" Edward Hasbrouck's The Practical Nomad blog (hasbrouck.org) - Jan. 25, 2008. ) *Dialogue Copyrighted Alan Watt - Feb. 7, 2008 (Exempting Music, Literary Quotes, and Callers' Comments)

Predictive Programming - "Change is Good", Medical Ethics, Bio-Ethical (Eugenicist) Committees, Socialism - Perpetual Childhood, Social Gathering Places, Destruction of Communication, Implantable Brain-Chips, Cyborgs, Guise of Helping the Disabled through Technology, Neuroscience, Cochlear Implants, Visual Implants, Genetic and Digital Enhancement, Neural Interfacing - Inter- to bury - Face, Sensory Amplifiers, Marketing Strategy, Cyber-think, Collective Consciousness, Redefining what is Human through Fiction, Artificial Intelligence, Occult - Golden People, Modification of the "Human Species", Totalitarian Control, Age of the Ultimate Control Freak, Compulsory Brain-Chip for Children - Military - Criminals, Behavior Modification, Free Flu-Shots, Professional Debates to Bring the Public to a Con-clusion, United Nations Agenda - No Private Property - Agenda 21, Lenin, the Real Purpose Behind the Chip, Will Mankind Go Out with a Whimper and Not with a Bang?, Public Conditioning through Mass Advertising, "Being You is Not Good Enough" Marketing, Engrams, Creating Discontent - Inability to Live up to Fictional Standards, Star Trek Series, New Age Palaver and Catch-Phrases, Hypnotists, Past Life Experiences, Valium Drug, Elite's Need for Public Complicity, Group Consensus, Fear of Using Your Brain, Lenin and Russell - Capitalist and Communist - Future Without Military or Police - Done Through Science, Published Books, Ego-Syntonic Public - Ignore the Unpleasant - Look for Pleasure, Thinking Positive - Turning Back on the Negative, Superstars, an On-Going Battle, the Business Plan - Time-Table of the Agenda, Public Do Not Know They Are Slaves, Being A Sentient Being - a Gift or a Curse, Hanging On to Sentience, (Song: "Imagine" by John Lennon) *Dialogue Copyrighted Alan Watt - Mar 14, 2007 (Exempting Music and Literary Quotes)