POPULARITY
Categories
What does Starfield look like in 2026?In Episode 53, we zoom out and look ahead at the future of Starfield—specifically the growing rumors around the mysterious Terran Armada DLC and what it could mean for the Settled Systems. From possible large-scale faction conflicts to fleet warfare and political upheaval, we break down what this expansion might be setting up and why it feels different from anything Bethesda has done before.We also dig into potential upgrades to the base game: long-requested quality-of-life improvements, systems Bethesda could overhaul as the game matures, and how ongoing updates and mods may reshape the overall experience heading into the next phase of Starfield's life cycle.Is Starfield slowly evolving into the space RPG it was always meant to be—or is Bethesda gearing up for something much bigger?Chat with us and other fans in our discord!https://discord.gg/exh8H4U9RT
Was ist "Die Welt von …?" Wenn wir über Video- und Computerspiele sprechen, die entweder elaborat ausgestaltete eigene Welten mit Hintergrundgeschichten haben oder über solche, die ihre Welt aus Literatur, Rollenspiel oder Film borgen, nehmen wir uns zuweilen die Zeit und sprechen ausführlicher über Lore jener Welten als das in den regulären Folgen möglich wäre. Im Format Die Welt von… erforschen Rahel Schmitz und Mháire Stritter die Legenden, die Geografie, die Geschichte, die Politik von diesen fiktiven Welten und holen sich dabei von Fall zu Fall ergänzende Expertise von ausgewiesenen Kennern und Kennerinnen der jeweiligen Welt. Worum geht's: Die Welt der The Elder Scrolls-Spiele ist kein klassisches Fantasy-Reich mit klaren Helden und Bösewichten, sondern ein komplexes Geflecht aus Kulturen, Mythen, Machtstrukturen und Widersprüchen. Tamriel ist ein Kontinent, der von Imperien beherrscht und zugleich von lokalen Traditionen, Religionen und ethnischen Spannungen geprägt ist. Götter existieren hier nicht nur als ferne Legenden, sondern greifen sichtbar in die Geschichte ein, während Wahrheit, Propaganda und Mythos oft ununterscheidbar ineinanderfließen. Die Spiele erzählen diese Welt selten direkt – sie erschließt sich über Bücher, Architektur, Rituale, Fraktionen und die Perspektiven ihrer Bewohner. In dieser Folge erkunden Rahel und Mháire die Eigenheiten dieser Spielwelt: ihre politische Struktur, die Rolle von Magie und Religion, das Nebeneinander von großer Historie und persönlicher Alltagserfahrung sowie die bewusste Mehrdeutigkeit vieler Erzählungen. Es geht darum, wie The Elder Scrolls Weltenbau betreibt, warum sich Tamriel je nach Region völlig anders anfühlt – und weshalb diese Serie bis heute eine der dichtesten und faszinierendsten Fantasy-Welten der Computerspielgeschichte hervorgebracht hat. Einen Gast gibt es auch: Diesmal kommt im Podcast neben den Sprecherinnen Louis Kresoviç zum Einsatz, der betreibt auf YouTube unter dem Namen Amemos den größten deutschsprachigen Lorecast zum Thema Elder Scrolls Podcast-Credits: Sprecher, Redaktion: Rahel Schmitz, Mháire Stritter Gast: Louis Kresoviç Audioproduktion: Sascha Blach, Christian Schmidt Titelgrafik: Paul Schmidt Intro, Outro: Nino Kerl (Ansage); Chris Hülsbeck (Musik) Die Podcastfolge, in der es um das Spiel Morrowind geht, ist parallel zu dieser Folge erschienen.
Worum geht's? Anfang der 2000er-Jahre steht das westliche Rollenspiel an einem Wendepunkt – und mit The Elder Scrolls III: Morrowind erscheint ein Titel, der mit seinen Schauwerten einen ziemlichen Hype auslöst, dabei aber seltsam sperrig ist. Statt gefälliger Fantasy-Kulissen erwartet die Spieler(innen) eine vulkanische Insel, geprägt von Asche, Pilztürmen, Knochenarchitektur und widersprüchlichen Kulturen. Morrowind erklärt wenig und führt kaum; zum Spielen braucht man Aufmerksamkeit, Neugier und Geduld. Dafür belohnt der Titel das Erforschen mit einer großen, vielfältigen Welt. Gunnar und Christian sprechen in dieser Folge über Morrowind als Brückenspiel zwischen alter 2D-Rollenspieltradition und moderner 3D-Open-World, über systemisches Spieldesign, Lernen durch Tun und das Gefühl, wirklich allein in einer fremden Welt zu sein. Es geht um Erkundung statt Wegweisung, um emergentes Storytelling, um sperrige Mechaniken und um die Frage, warum dieses Spiel für viele bis heute eine ganz eigene, unverwechselbare Geschmacksrichtung des Rollenspiels darstellt. Infos zum Spiel: Thema: The Elder Scrolls III: Morrowind Erscheinungstermin: Mai 2002 Plattform: PC (Windows), Xbox Entwickler: Bethesda Game Studios Publisher: Bethesda Softworks Genre: Rollenspiel Designer: Todd Howard, Ken Rolston, Michael Kirkbride Musik: Jeremy Soule Produktions-Credits: Sprecher, Redaktion: Christian Schmidt, Gunnar Lott Audioproduktion: Johannes DuBois, Christian Schmidt Titelgrafik: Paul Schmidt Intro & Outro: Nino Kerl (Ansage); Chris Hülsbeck (Musik)
Star Trek has found its new Bones and Sulu, yet we have to wait a while before we actually see them. The video game industry lost a true legend, and we salute everything Vince Zampella brought us. Marvel goes back to what it knows for Doomsday, and Macauly decides what is and isn't a Christmas Movie. Plus we may have to wait a little longer for 007's video game return.
« Jésus se présente à nous »Selon notre identité : Il vient comme le bon berger pour ses brebis. Il connaît chacun de nous personnellement, nous appelle par notre nom et s'adresse à nous de manière intime.Selon notre localisation : Comme à la piscine de Bethesda, Jésus nous rejoint là où nous sommes. Ce lieu symbolique représente l'Église (la piscine), les cinq ministères (les portiques), et la Parole de Dieu (l'eau).Selon sa grâce : Son intervention ne dépend pas de nos mérites, mais de sa grâce souveraine. Il nous devance, nous relève et nous restaure.Selon ses méthodes : Jésus agit souvent de manière inattendue : par une parole, une question ou un ordre simple, au moment précis qu'Il choisit.Jésus ne se révèle pas de façon uniforme, mais toujours de manière personnelle, selon notre identité, notre situation, sa grâce, et ses voies.Soutenez-nous sur PayPal !
Feeling a little down about that holiday shift? Then this is a must-listen episode! Join the co-hosts as they share their own experiences, stories, and practical, compassionate strategies to beat the nursing holiday blues and show up strong for your patients. Also, learn about the time-honored legend of the Cookie-Crusted Ham. MEET OUR CO-HOSTS Samantha Bayne, MSN, RN, CMSRN, NPD-BC is a nursing professional development practitioner in the inland northwest specializing in medical-surgical nursing. The first four years of her practice were spent bedside on a busy ortho/neuro unit where she found her passion for newly graduated RNs, interdisciplinary collaboration, and professional governance. Sam is an unwavering advocate for medical-surgical nursing as a specialty and enjoys helping nurses prepare for specialty certification. Kellye' McRae, MSN-Ed, RN is a dedicated Med-Surg Staff Nurse and Unit Based Educator based in South Georgia, with 12 years of invaluable nursing experience. She is passionate about mentoring new nurses, sharing her clinical wisdom to empower the next generation of nurses. Kellye' excels in bedside teaching, blending hands-on training with compassionate patient care to ensure both nurses and patients thrive. Her commitment to education and excellence makes her a cornerstone of her healthcare team. Marcela Salcedo, RN, BSN is a Floatpool nightshift nurse in the Chicagoland area, specializing in step-down and medical-surgical care. A member of AMSN and the Hektoen Nurses, she combines her passion for nursing with the healing power of the arts and humanities. As a mother of four, Marcela is reigniting her passion for nursing by embracing the chaos of caregiving, fostering personal growth, and building meaningful connections that inspire her work. Eric Torres, ADN, RN, CMSRN is a California native that has always dreamed of seeing the World, and when that didn't work out, he set his sights on nursing. Eric is beyond excited to be joining the AMSN podcast and having a chance to share his stories and experiences of being a bedside medical-surgical nurse. Maritess M. Quinto, DNP, RN, NPD-BC, CMSRN is a clinical educator currently leading a team of educators who is passionately helping healthcare colleagues, especially newly graduate nurses. She was born and raised in the Philippines and immigrated to the United States with her family in Florida. Her family of seven (three girls and two boys with her husband who is also a Registered Nurse) loves to travel, especially to Disney World. She loves to share her experiences about parenting, travelling, and, of course, nursing! Sydney Wall, RN, BSN, CMSRN has been a med surg nurse for 5 years. After graduating from the University of Rhode Island in 2019, Sydney commissioned into the Navy and began her nursing career working on a cardiac/telemetry unit in Bethesda, Maryland. Currently she is stationed overseas, providing care for service members and their families. During her free time, she enjoys martial arts and traveling.
Linktree: https://linktr.ee/AnalyticJoin The Normandy For Additional Bonus Audio And Visual Content For All Things Nme+! Join Here: https://ow.ly/msoH50WCu0KIn this segment of Notorious Mass Effect, host Analytic Dreamz breaks down Fallout Season 2 on Amazon Prime Video, which premiered early on December 17, 2025, shifting to the iconic New Vegas setting from the 2010 game and featuring the series' signature sniper tower dinosaur. Analytic Dreamz highlights its record-breaking Rotten Tomatoes scores: 98% critics (later adjusted to 96%), 96% audience (now 95%), topping all live-action video game adaptation Season 2s and tying the highest audience score overall, surpassing The Last of Us and others for dual-season averages.Season 1 earned 17 Emmy nominations including Best Drama, with wins for costumes and prosthetics. Todd Howard confirms the show is canon, set in 2296, influencing Fallout 5 post-2035. Bethesda capitalizes with Fallout Shelter's first "Viva New Vegas" Season Pass (TV tie-in quests, dwellers), Fallout 4 Anniversary Edition, Fallout 76 updates, and Prime Gaming promotions.Support this podcast at — https://redcircle.com/analytic-dreamz-notorious-mass-effect/donationsPrivacy & Opt-Out: https://redcircle.com/privacy
Linktree: https://linktr.ee/AnalyticJoin The Normandy For Additional Bonus Audio And Visual Content For All Things Nme+! Join Here: https://ow.ly/msoH50WCu0K In this segment of Notorious Mass Effect, host Analytic Dreamz breaks down Fallout Season 2 on Amazon Prime Video, which premiered early on December 17, 2025, shifting to the iconic New Vegas setting from the 2010 game and featuring the series' signature sniper tower dinosaur. Analytic Dreamz highlights its record-breaking Rotten Tomatoes scores: 98% critics (later adjusted to 96%), 96% audience (now 95%), topping all live-action video game adaptation Season 2s and tying the highest audience score overall, surpassing The Last of Us and others for dual-season averages.Season 1 earned 17 Emmy nominations including Best Drama, with wins for costumes and prosthetics. Todd Howard confirms the show is canon, set in 2296, influencing Fallout 5 post-2035. Bethesda capitalizes with Fallout Shelter's first "Viva New Vegas" Season Pass (TV tie-in quests, dwellers), Fallout 4 Anniversary Edition, Fallout 76 updates, and Prime Gaming promotions.Support this podcast at — https://redcircle.com/analytic-dreamz-notorious-mass-effect/donationsPrivacy & Opt-Out: https://redcircle.com/privacy
Ver en YouTube: https://youtu.be/Cw87Cse1evA Comenzamos nuevo seguimiento en Criterio en Serie. Lo hacemos con la segunda temporada de Fallout, la adaptación de la saga de videojuegos de Bethesda, y que tan buen sabor de boca nos dejó con su primera temporada. Nos ponemos en dirección a New Vegas, escenario emblemático de la saga, recuperando a nuestros protagonistas Lucy, el ghoul y Máximus, además de toda la caterva de secundarios a los que se van a sumar sorprendentes nuevos personajes. Ale Oñate, Juandi y Salva Vargas se lanzan al yermo en busca de refugio y provisiones. Si necesitas refrescar la primera temporada, no te pierdas el podcast que le dedicamos repasando sus ocho episodios con todo lujo de detalles y curiosidades: https://go.ivoox.com/rf/128100989 Y si necesitas más conocimiento sobre el universo Fallout en sus juegos, con este otro podcast seguro que no te pierdes en su páramo: https://go.ivoox.com/rf/128100989 Este programa cuenta con la producción ejecutiva de nuestr@s mecenas, l@s grandes, l@s únicos Kamy, Lobo Columbus, Enfermera en Mordor, Javier Ramírez, La Casa del Acantilado, Shinyoru, Lestat, Kal-el__80, Cohaggen, Elena Gómez, Olgafies, José Ángel Sanz, Rudy Ayose, Miguel García, Ian Pérez, Ed Salas, Mario López, Miguel Ángel. ¿Quieres ayudarnos a seguir mejorando y creciendo? Pues tienes varias opciones para ello. Dándole Me gusta o Like a este programa. Por supuesto estando suscrito para no perderte ninguno de los próximos episodios, y ya para rematar la faena, compartiendo el podcast con tus amigos en redes sociales y hablando a todo el que te cruce en la calle de nosotros…. Y todo esto encima, GRATIS!!! Y si ya nos quieres mucho, mucho, mucho y te sobra la pasta…. Puedes hacerlo económicamente de varias formas: Apoyo en iVoox: En el botón APOYAR de nuestro canal de iVoox y desde 1,49€ al mes: https://acortar.link/emR6gd Invitándonos a una birra en Ko-Fi: por solo 2€ nos puedes apoyar en: https://ko-fi.com/criterioceropodcast Patreon: por sólo 3€ al mes en: https://patreon.com/CriterioCeroPodcast PayPal: mediante una donación a criterioceropodcast@gmail.com También nos podéis ayudar económicamente de forma indirecta si tenéis pensado suscribiros a las modalidades Premium o Plus de iVoox al hacerlo desde estos enlaces: Premium Anual: https://acortar.link/qhUhCz Premium Mensual: https://acortar.link/gbQ4mp iVoox Plus Mensual: https://acortar.link/y7SDmV Con cada rupia que nos llegue sufragamos los costes del programa al mes, invertiremos en mejorar los equipos y por supuesto, nos daremos algún que otro capricho . Las recompensas por apoyarnos se explican en nuestro blog: https://criterioceropodcast.blogspot.com/2023/08/quieres-ayudar-criterio-cero-mejorar.html También puedes hacerte con algo de merchandising de Criterio Cero. Camisetas, Sudaderas, tazas o mochilas en el siguiente enlace: https://www.latostadora.com/shop/criteriocero/?shop_trk Y Criterio Cero no acaba ya en el audio, ahora también nos tenéis en vídeo: En Twitch hacemos directos de Criterio En Serie: https://www.twitch.tv/criteriocero En YouTube: https://www.youtube.com/@criteriocero Y también puedes seguirnos en nuestras diferentes redes sociales: En Telegram en nuestro grupo: https://t.me/criteriocerogrupo En Facebook en nuestro grupo: https://www.facebook.com/groups/630098904718786 Y en la página: https://www.facebook.com/criterioceropodcast ✖️ En X (el difunto Twitter) como @criteriocero En Instagram como criterioceropodcast En TikTok como criteriocero ✉️ Para ponerte en contacto con nosotros al correo criterioceropodcast@gmail.com De paso aprovechamos para recomendaros podcasts que no debéis perderos: Hudson´s Podcast, Puede ser una charla más, Luces en el horizonte, La Catedral Atroz, La guarida del Sith, Crónicas de Nantucket, Más que cine de los 80, Fílmico, Tiempos de Videoclub, Sector Gaming , El Dátil de ET, La Casa del Acantilado, Kiosko Chispas, Just Live it, Filmotecast, La Tetera, Fuera de continuidad, Campamento Krypton, La órbita de Endor, Archivo007, El bastón de Chaplin
Send us a textDr. Edward Holland is a world-renowned leader in corneal transplantation and severe ocular surface disease, and is the Co-Founder of the Holland Foundation for Sight Restoration ( HFSR - https://www.hollandfoundationforsight.org/ ) is a 501(c)(3) nonprofit organization, dedicated to transforming the lives of individuals affected by these conditions, including limbal stem cell deficiency (LSCD) – a rare and devastating condition that can result in chronic pain, profound vision loss, and blindness.Through this HFSR initiative, Centers of Excellence (COEs) focused on the advanced sight restoration procedures of Ocular Surface Stem Cell Transplantation (OSST) are being launched across the country. As part of its mission, the foundation is also committed to broadening education and training so that more physicians nationwide can learn and implement The Cincinnati ProtocolTM for the management of these patients.Dr. Holland is also the Director of Cornea Services at Cincinnati Eye Institute ( https://www.cincinnatieye.com/doctors/edward-j-holland-m-d/ ) and Professor of Ophthalmology at the University of Cincinnati ( https://med.uc.edu/landing-pages/profile/Index/Pubs/hollanej ). Dr. Holland attended the Loyola-Stritch School of Medicine in Chicago and trained in Ophthalmology at the University of Minnesota. He completed a fellowship in cornea and external disease at the University of Iowa and then completed a second fellowship in ocular immunology at the National Eye Institute, National Institutes of Health in Bethesda, Maryland. Dr. Holland formerly served as the President for the American Society of Cataract and Refractive Surgery and served as the Program Chair for 12 years. Dr. Holland was a former member of the Board of Trustees for the American Academy of Ophthalmology and served as the Secretariat of the Annual Meeting. Dr. Holland has served as the Chair of the Eye Bank Association and was the former Chair of the Medical Advisory Board as well as a longtime member of the Board of Directors. Robert Dempsey, MBA is also a Co-Founder of the Holland Foundation for Sight Restoration.Mr. Dempsey brings more than two decades of domestic and global experience in the ophthalmic space driving successful drug development, business transactions and commercialization. His widespread experience in Ophthalmology stems from diverse Leadership roles across Commercial, Business Development, Medical Affairs and Venture Backed Startups. He brings deep relationships with Key Opinion Leaders and comprehensive knowledge of the ophthalmic ecosystem. Most recently, Mr. Dempsey served as the Chief Executive Officer for AsclepiX Therapeutics, following his CEO role at TearClear accelerating business and commercial strategies which led to several value inflection points and positive FDA engagements. Mr. Dempsey holds a Master's in Business Administration and a Bachelor of Science in healthcare marketing from Northeastern University in Boston, Massachusetts.Important Episode Link - Holland Foundation for Sight Restoration Launches Light After Darkness Fundraising Campaign - https://www.globenewswire.com/news-release/2025/10/22/3171067/0/en/Holland-Foundation-for-Sight-Restoration-Launches-Light-After-Darkness-Fundraising-Campaign.html#EdwardHolland #RobertDempsey #HollandFoundationForSightRestoration #OcularSurfaceStemCellTransplantation #Ophthalmology #LightAfterDarkness #Cornea #LimbalStemCell #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #STEM #Innovation #Technology #Science #ResearchSupport the show
The world lost a great director this week, and its not gonna be the same without him. We've got two weeks of stories to cover, The Game Awards got swept, and also gave us to Star Wars game announcements. The Golden Globes are set, and will the Bear be dethroned by The Studio? The Warner Bros and Netflix saga has begun, despite Paramount's eagerness, CCXP brought the trailers, and Wake Up Dead man dropped on Netflix. Come take a listen.
BACK TO THE WASTELAND!! Fallout Full Episode Reaction Watch Along: / thereelrejects Rula patients typically pay $15 per session when using insurance. Connect with quality therapists and mental health experts who specialize in you at https://www.rula.com/REJECTS #rulapod FALLOUT Season 1 Reactions: • Fallout Reaction Gift Someone (Or Yourself) A Stranger Things RR Tee! https://shorturl.at/hekk2 Vecna: The Mind Slayer tee by @G9DESIGN & Dr. Stranger Things tee by @SASAMIIKU — perfect for hardcore fans & collectors alike! Greg Alba & Michael Tessler RETURN to give their Fallout Season 2 Reaction, Recap, Analysis, Breakdown, & Spoiler Review!! The Season 2 premiere of Prime Video's Fallout (Season 2, Episode 1), kicks off the next chapter of the hit post-apocalyptic series inspired by Bethesda's Fallout video games. Picking up after the explosive fallout (literally and emotionally) of Season 1, the premiere sets the tone for a darker, more expansive journey across the Wasteland as long-buried truths come to light and new factions begin to move into position. Follow Michael Tesslerr:https://www.instagram.com/mjtessler/ Intense Suspense by Audionautix is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/... Support The Channel By Getting Some REEL REJECTS Apparel! https://www.rejectnationshop.com/ Follow Us On Socials: Instagram: https://www.instagram.com/reelrejects/ Tik-Tok: https://www.tiktok.com/@reelrejects?lang=en Twitter: https://x.com/reelrejects Facebook: https://www.facebook.com/TheReelRejects/ Music Used In Ad: Hat the Jazz by Twin Musicom is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/ Happy Alley by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/... POWERED BY @GFUEL Visit https://gfuel.ly/3wD5Ygo and use code REJECTNATION for 20% off select tubs!! Head Editor: https://www.instagram.com/praperhq/?hl=en Co-Editor: Greg Alba Co-Editor: John Humphrey Music In Video: Airport Lounge - Disco Ultralounge by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/ Ask Us A QUESTION On CAMEO: https://www.cameo.com/thereelrejects Follow TheReelRejects On FACEBOOK, TWITTER, & INSTAGRAM: FB: https://www.facebook.com/TheReelRejects/ INSTAGRAM: https://www.instagram.com/reelrejects/ TWITTER: https://twitter.com/thereelrejects Follow GREG ON INSTAGRAM & TWITTER: INSTAGRAM: https://www.instagram.com/thegregalba/ TWITTER: https://twitter.com/thegregalba Learn more about your ad choices. Visit megaphone.fm/adchoices
BACK TO THE WASTELAND!! Fallout Full Episode Reaction Watch Along: / thereelrejects Rula patients typically pay $15 per session when using insurance. Connect with quality therapists and mental health experts who specialize in you at https://www.rula.com/REJECTS #rulapod FALLOUT Season 1 Reactions: • Fallout Reaction Gift Someone (Or Yourself) A Stranger Things RR Tee! https://shorturl.at/hekk2 Vecna: The Mind Slayer tee by @G9DESIGN & Dr. Stranger Things tee by @SASAMIIKU — perfect for hardcore fans & collectors alike! Greg Alba & Michael Tessler RETURN to give their Fallout Season 2 Reaction, Recap, Analysis, Breakdown, & Spoiler Review!! The Season 2 premiere of Prime Video's Fallout (Season 2, Episode 1), kicks off the next chapter of the hit post-apocalyptic series inspired by Bethesda's Fallout video games. Picking up after the explosive fallout (literally and emotionally) of Season 1, the premiere sets the tone for a darker, more expansive journey across the Wasteland as long-buried truths come to light and new factions begin to move into position. Follow Michael Tesslerr:https://www.instagram.com/mjtessler/ Intense Suspense by Audionautix is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/... Support The Channel By Getting Some REEL REJECTS Apparel! https://www.rejectnationshop.com/ Follow Us On Socials: Instagram: https://www.instagram.com/reelrejects/ Tik-Tok: https://www.tiktok.com/@reelrejects?lang=en Twitter: https://x.com/reelrejects Facebook: https://www.facebook.com/TheReelRejects/ Music Used In Ad: Hat the Jazz by Twin Musicom is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/ Happy Alley by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/... POWERED BY @GFUEL Visit https://gfuel.ly/3wD5Ygo and use code REJECTNATION for 20% off select tubs!! Head Editor: https://www.instagram.com/praperhq/?hl=en Co-Editor: Greg Alba Co-Editor: John Humphrey Music In Video: Airport Lounge - Disco Ultralounge by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/by/4.0/ Ask Us A QUESTION On CAMEO: https://www.cameo.com/thereelrejects Follow TheReelRejects On FACEBOOK, TWITTER, & INSTAGRAM: FB: https://www.facebook.com/TheReelRejects/ INSTAGRAM: https://www.instagram.com/reelrejects/ TWITTER: https://twitter.com/thereelrejects Follow GREG ON INSTAGRAM & TWITTER: INSTAGRAM: https://www.instagram.com/thegregalba/ TWITTER: https://twitter.com/thegregalba Learn more about your ad choices. Visit megaphone.fm/adchoices
When Jesus saw him lying there and learned that he had been in this condition for a long time, he asked him, "Do you want to get well?" "Sir," the invalid replied, "I have no one to help me into the pool when the water is stirred. While I am trying to get in, someone else goes down ahead of me" (John 5:6-7). Jesus loved to ask questions. Some were innocent enough, like "Will you get me some water?" (4:7). Some were asked to encourage people to leave him alone, like the time he asked the Jewish establishment, "Where did John get his authority, from man or from God?" (Matthew 21). Others helped a listener probe deeper into Jesus' identity, like when he asked his disciples, "Who do people say that I am?" Still others, like the one in our text, are a set up. The question does seem a bit strange, but the setting helps us get a handle on it. Jesus went up to Jerusalem, the city of peace. He went to celebrate one of the Jewish feasts, a joyful event praising God for his work of deliverance. The scene is the pool named Bethesda, which means 'house of mercy.' So, the location is peace, joy, mercy. We are expecting a happy story. Instead, we are told that this pool is surrounded by a great number of disabled people, but we focus on one person. He has been lying there for 38 years. That's a long time by anyone's reckoning. We might want to know about the magical nature of this pool. How is it that only the first person who touches the pool after it is stirred gets healed? Was it really an angel of the Lord who stirred the pool? But Jesus does not oblige our curiosity. He wants us to focus on this person lying here for 38 years. How many times has he seen the water stirred and he has not been able to touch it because someone else was always faster? Has he given up hope? Has he given in to his condition and expects to live out his life begging for scraps from passing feast goers? Jesus asks, "Do you want to get well?" Some suggest that Jesus wanted to know if the man had any hope left; it being a requirement for healing. Others suggest that Jesus was exposing that the man had become comfortable in his paralysis and did not want to get better. He needed to start taking responsibility for himself. These issues are not part of this story. The man doesn't answer Jesus' question. He just says, "Hey man, what I want doesn't really matter. I can't get to the pool. I won't get healed." The man's got nothing. Jesus heals him. His mercy is free. He comes to bring it to those who are without hope. He comes to bring it to those who don't expect it anymore. He comes in mercy to bring peace and joy. Are you looking for God's mercy? Are you trying to figure out how to answer Jesus' question? The answer is not important; Jesus brings mercy wherever he goes. You don't need to look elsewhere. Look to Jesus. As you journey on, go with the blessing of God: May the peace of the Lord Christ go with you, wherever he may send you. May he guide you through the wilderness, protect you through the storm. May your day end with rejoicing at the wonders he has shown you. May you rest in his provision as he brings night, and then new dawn.
Co-hosts Ryan Piansky, a graduate student and patient advocate living with eosinophilic esophagitis (EoE) and eosinophilic asthma, and Holly Knotowicz, a speech-language pathologist living with EoE who serves on APFED's Health Sciences Advisory Council, interview Fei Li Kuang, MD, PhD, an allergist and immunologist, at Northwestern Medicine, about receiving two APFED HOPE on the Horizon Grants. Disclaimer: The information provided in this podcast is designed to support, not replace, the relationship between listeners and their healthcare providers. Opinions, information, and recommendations shared in this podcast are not a substitute for medical advice. Decisions related to medical care should be made with your healthcare provider. Opinions and views of guests and co-hosts are their own. Key Takeaways: [:50] Co-host Ryan Piansky introduces this episode, brought to you thanks to the support of Education Partners GSK, Sanofi, Regeneron, and Takeda. Ryan introduces co-host Holly Knotowicz. [1:14] Holly introduces today's topic, two APFED HOPE on the Horizon Pilot Grant Projects and today's guest, Fei Li Kuang, MD, PhD, an Assistant Professor in the Division of Allergy and Immunology at Northwestern University Feinberg School of Medicine in Chicago, Illinois. [1:42] Dr. Kuang is a physician-scientist who takes care of patients with eosinophilic disorders and also performs laboratory research on these disorders in her lab, often using patient samples. Holly thanks Dr. Kuang for joining us. [2:05] As a child, Dr. Kuang always wanted to be a scientist. She is so grateful to live out her childhood dream, and it's because of the amazing people who have supported her, most importantly, her parents. [2:29] In graduate school, Dr. Kuang studied B cells. When she went on to do an allergy fellowship, she thought she would study B cells and care for patients with B cell problems. Instead, she fell in love with allergy and eosinophilic disorders. [2:50] Dr. Kuang is here, in part, because of the different mentors she has had, and in large part, because of the patients she has met along the way. [3:20] Dr. Kuang had the opportunity to work with Amy Klion at the NIH in a clinical trial to treat patients with a drug that gets rid of eosinophils. She says it was a dream come true after her training. [4:02] She says she learned so much about eosinophils, their unusual biology, and the mystery behind what they are here for. She got hooked. [4:15] Dr. Kuang thinks the patients you meet in a clinical trial in a special place like NIH occupy a space in your heart that makes you want to keep working on the subject area. [4:34] Patients in a clinical trial have given up a bunch of their time to travel to Bethesda, Maryland. For the trial Dr. Kuang participated in as a Fellow, it was a good year of their time to come out and do it. [4:47] Dr. Kuang felt there were so many interesting questions, from an intellectual point of view, but there was also a real need from patients with chronic conditions. It was a beautiful opportunity to marry scientists with physicians in training. [5:36] Dr. Kuang shares some knowledge about eosinophils. They are white blood cells that are in all of us. They have little pink packages or granules that "jumped out" in the light microscope almost 200 years ago, when we first identified them. [6:00] Dr. Kuang says that animals, dating back to reptiles, and different species of dolphins, all have eosinophils. A veterinary scientist, Dr. Nicole Stacy of the University of Florida, has taken photos of eosinophils from all these different species. [6:21] They've been around for a long time. What are they good for? What we know is that they are associated with disease conditions, such as asthma and others, including leukemia. Those were the classic first studies of eosinophils. [6:42] Now, we have a different mindset about eosinophils from work by the late James Lee at Mayo Clinic, Arizona. [6:58] Dr. Kuang credits Dr. Lee with suggesting that eosinophils not just cause us problems but also help treat parasitic infections, maintain tissue homeostasis, help wound healing, and tissue repair. That's a new area we are beginning to appreciate. [7:41] Dr. Kuang says we need to be open-minded that in some circumstances, eosinophils may be helpful or innocent. Now we have tools to start to understand some of that. We need to collect information from patients being treated with medicines. [8:10] Ryan tells of being diagnosed as a kid. Doctors explained to him that eosinophils fight parasites, but in some people, they get confused and attack the esophagus. That's EoE. That was easy to understand, but he knew that the researchers knew more. [8:53] Ryan is grateful to the patient population around eosinophilic esophagitis, and is proud of APFED's support of patients and caregivers with HOPE Grants. APFED has the HOPE on the Horizon Research Program, entirely funded by community donations. [9:13] To date, APFED has directed more than $2 million toward eosinophilic disease research initiatives through various grant programs. As a patient advocacy organization, APFED works with fantastic researchers who submit innovative research ideas. [9:32] These research ideas go through an extensive and competitive peer-review process, supported by researchers and clinicians in the APFED community. [9:42] Today, we're going to discuss two different projects supported by HOPE Pilot Grants with Dr. Kuang. [10:00] Dr. Kuang thinks there are two ways these grant programs are important to patients. One is advancing research by nurturing seedling investigators. Dr. Kuang got her first grant when she was a Fellow. It was an incredible opportunity. [10:25] These grant programs also nurture seedling ideas that don't have enough evidence yet to garner the larger NIH grants, and so forth. There are other sources for grants: pharmaceutical companies. The grant programs are for seeds. [10:49] Patients need to know that there are new things that are given some chance of being tested out. Research takes some time, and the FDA process of getting a drug approved is long. [11:04] For the newly diagnosed patient, it can feel overwhelming. It feels like there's a loss of control. Sometimes, participating in something like APFED, being part of a community, gives back a sense of control that is lost when you're handed a diagnosis. [11:45] For patients who have had it for a long time, when they participate in research and become engaged in organizations like APFED, they know they may not directly benefit today, they may benefit later, but they hope future patients will benefit. [12:21] That gives them a sense of control and hope that things will be better for the next generation. We all want that, especially in medicine, in something that we don't have a very deep understanding of. [12:58] Dr. Kuang received two HOPE Pilot Grants, one in 2018 and one in 2022. The first grant was awarded when she was a Fellow at the NIH. [13:05] That first grant explored some effects of eosinophilic depletion of pathogenic lymphocytes in hypereosinophilic syndrome and overlaps with EGIDs. Ryan asks for a broad overview of that research. [13:25] When Dr. Kuang was a Fellow at the NIH, they were doing a Phase 2 clinical trial, looking at "blowing up" eosinophils in patients who have a lot of them, hypereosinophilic syndrome patients. [13:39] They included patients who had eosinophilic GI disease, often beyond the esophagus. They may have esophageal involvement, but sometimes their stomach is impacted, sometimes their large bowel is impacted, with related symptoms. [13:57] What Dr. Kuang and the team noticed in the trial was that just within that little group of patients, there were people who did well, and people who did much better than before, but would have recurrent symptoms, and with no eosinophils in their GI tissues. [14:16] The researchers wanted to know what was causing these problems for the patient. If you take eosinophils away, what other factors will impact the immune system of the patient, semi-long-term? [14:32] Their focus was on these groups of patients who had different responses. They looked at the white blood cells that had been previously described as being the responsible, "bad" T cells that lead to eosinophils in the gut. [14:49] They found that the patients who had recurrent flares of the disease had more of the bad T cells, and the patients who responded well and never complained again about symptoms did not. [15:03] That allowed researchers to identify that there were subsets of patients with the disease that they were calling the same thing. [15:18] Dr. Kuang says that work also led them to find that those cells were being reported in patients who had food allergies for which they needed an epinephrine auto-injector. [15:27] The researchers were curious whether that was just a food allergy issue, or only applied if you had food allergies and eosinophilic GI disease. That HOPE project allowed them to do a pilot study to look at food allergy patients, too. They did, and published it. [15:45] They published that in patients who have a food allergy and have these T cells, the insides of those cells make different messages for the immune system than the ones that the researchers had previously described. [16:01] In looking for why there were differences in those responses, they accidentally found that there were differences inside these cells in a completely different disease, which also had these T cells. [16:21] Dr. Kuang says that the finding was kind of a surprise. If they had found anything in the eosinophilic GI disease patients, that would have been good. They also looked at the epithelial cells and the structure of the GI lining. [16:42] Even though there were no eosinophils in the GI lining in the patients who had been treated with a biologic that depleted eosinophils, their GI lining still looked like the GI lining of patients who had eosinophilic GI disease. [16:55] Dr. Kuang asked what was creating those spots. Our gut lining sheds, so there should have been an opportunity for the GI lining to turn over and look new. Something was there, making signals to create these spots. They did a different publication on that. [17:21] The data from the HOPE Pilot study allowed Dr. Kuang to apply for larger grants. It allowed her to propose to the company that made this drug, when they did the Phase 3 trial, to insert into that special study the study on eosinophilic GI disease. [17:48] Do patients with eosinophilic GI disease do better or worse on this drug, and how do the T cells look in that trial? That HOPE Grant gave Dr. Kuang the data to ask the drug company to give her money to study it in an international cohort of patients. [18:17] There were only 20 patients in that first NIH trial, who gave a year of their life, coming to NIH all the time. They continued to be in the study until the drug was approved for asthma. [18:28] Dr. Kuang says the main reason the company did the Phase 3 trial, which is expensive, and the market share is not huge because it's a rare disease, is that two of the patients went to bat for this disease population. [18:47] The two patients went and showed the business people what they looked like before, what the drug had done for them, and how their lives had changed. It wasn't the doctors or the great paper from the trial, but the patients who convinced the company. [19:01] Dr. Kuang says she was so floored by that and moved by what they did for the community. She is grateful. [19:24] Since the Phase 3 trial, Dr. Kuang and the other researchers realized they had not fully studied the eosinophils. They had studied them in part. They found differences in response. This inspired the second APFED HOPE Pilot Grant. [21:19] In 2022, Dr. Kuang received a two-year APFED HOPE Pilot Grant to examine how blood eosinophils in Eosinophilic Gastrointestinal Diseases differ from those of other eosinophilic diseases and how T cells in EGIDs differ from those in food allergies. [21:49] Dr. Kuang says normally, the biggest place of residence for eosinophils is the GI tract. That's where they are normally seen in people who do not have eosinophilic disorders. [21:59] People who have eosinophilic disorders that attack other parts of the body, asthma, and rarely, the heart. Dr. Kuang was curious to know why one person and not the other? [22:15] Patients who have eosinophilic GI disease often ask, How do you know this high level in the blood is not going to attack my heart or my lungs in the future? Dr. Kuang does not know. [22:29] Dr. Kuang says, looking at the cohort at the NIH, that for many patients who have both GI organ involvement and some other space, when they first went to see a provider, their first complaint was a GI condition. [22:54] If the doctor had only diagnosed a GI condition, nothing else, that would have been wrong. Those patients may not have been monitored as well. A third of the patients originally presented like that. [23:11] What that meant was that we should be paying attention to patients who have GI disease who have lots of eosinophils in their blood. Moving forward, if there are new complaints, we need to investigate. We can't forget they have that. [23:27] Dr. Kuang asks, Wouldn't it be great if we had a better tool than needing to wait? Wouldn't it be great if we had a biomarker that said the eosinophils have switched their target location and are going somewhere else? [23:41] One way to do that is to take different groups of eosinophils and look for differences between those that never target the GI tract and those that do. In patients who have EoE, the eosinophils only target or cause problems in the esophagus. [23:58] Are their eosinophils any different than those of a healthy person, with none of these conditions? That was the goal of that study. [24:10] T cells are another type of white blood cell. They contain a memory of foreign things they have encountered, which allows them to glom onto flu, COVID, peanuts, pollen, that kind of thing. They remember. [24:32] Dr. Kuang says they learned that T cells, at least in the mouse model, are required in the development of eosinophilic esophagitis. The mice in the old study, where mice were forced to develop EoE, did not get EoE if you removed their T cells. [24:50] In the first APFED HOPE grant study, Dr. Kuang found T cells in the blood and tissue of both EGIDs and food allergy patients, but the insides of the T cells were different. The food allergy patients were children recruited by a pediatric allergist. [25:19] In the second APFED HOPE grant study, at Northwestern, Dr. Kuang recruited her adult food allergy patients. That was a way to validate what they found in the first study and move further to better characterize those T cells in the two different diseases. [25:47] Dr. Kuang says we're at a point where we've recruited a lot of people. She says it's amazing what people are willing to do. It's very humbling. [26:06] Dr. Kuang's team in the lab is really great, too. To accommodate patients, they would see them after work, if that's what they had to do to isolate eosinophils. So they did that, and now they are in the process of analyzing that data. It's really exciting. [26:28] What's exciting is that they are seeing results that show that eosinophilic GI disease patients have circulating eosinophils that are different from the eosinophils of people who don't have GI involvement, and from people who have EoE. [26:46] The EoE patients have eosinophils different from those of healthy donors. Dr. Kuang says there's a lot of promise for perhaps unique signatures that could help define these conditions; maybe someday without biopsying, but that's a long time away. [27:16] Dr. Kuang says they will focus on some candidate targets and try to recreate some of that in a dish with eosinophils from healthy people. [27:26] What are the signals that lead eosinophils to do this, and can we translate that back to available drugs that target certain cytokines or other pathways, and maybe give some insight to develop drugs that target other pathways for these diseases? [28:17] Ryan thinks it's exciting that this research is narrowing in on not only the different symptoms, but also how the eosinophils are acting differently in these populations. [28:44] Dr. Kuang is super excited about this research. You could imagine that all eosinophils are the same, but you don't know until you look. When they looked, using the newest technology, they found there were differences. [29:33] Dr. Kuang says it is thought that T cells respond to triggers. We don't think eosinophils have a memory for antigens. T cells do. That's one of their definitions. When T cells react to a trigger, they give out messages through cytokines or by delivery. [30:20] Those are the messages that recruit eosinophils and other cells to come and stir up some trouble. [30:28] In the mouse model, where you don't have the T cells, and you don't get eosinophilic esophagitis in the particular way they made it happen in a mouse, that middle messenger is gone, so the eosinophils don't know where to go. [30:44] With drugs that take out eosinophils, you think that you've gotten rid of the cell that creates all the problems. It shouldn't matter what the message says because there's no cell there to cause the damage. [30:58] What Dr. Kuang learned is that, at least in certain eosinophilic GI diseases, that's not true. You erase the eosinophils from the picture, but that message is still coming. [31:10] Who's carrying out the orders? Or is that message maintaining the wall of epithelial cells in a certain way that we didn't appreciate because the eosinophils were also there? [31:24] It's important to study both, because one is the messenger and the other is one of the actors. Whether all of the actions taken by eosinophils are bad, or maybe some of them were meant to be good, we have yet to learn. [31:40] At the moment, we're using it as a marker for disease activity, and that may change in the future, as we learn more about the roles of these cells in the process. [31:50] We have drugs now that target eosinophils and drugs that target T cells. Dr. Kuang thinks it's important to study both and to study the impact of these drugs on these cells. [32:02] You could theoretically use these drugs to understand whether, if someone responds to it, what happens to these cells, and if someone doesn't respond to it, what happens to these cells, and how this disease manifests in this flavor of patients. [32:54] Dr. Kuang says, Often in science, we take a model. We think this works this way. Then, if this works this way, we expect that if we remove this, these things should happen. We did that with the first clinical trial, with NIH patients. [33:10] It didn't quite happen the way we thought, so we had to go looking for explanations. These were unusual setbacks. Sometimes you have unusual findings, like the food allergy part. [33:24] When Dr. Kuang went to Northwestern, she saw different cohorts of patients than she saw at NIH. She saw people who were seen every day, which is a different spectrum than those who are selected to be enrolled in a study protocol at the NIH. [33:42] That broadened her viewpoint. It's maybe not all food-triggered. They were seeing adults who'd never had food allergies or asthma their whole life, and they had eosinophilic esophagitis suddenly as a 50-year-old. There's a significant group of them. [34:10] What Dr. Kuang learned and tries to be open-minded about is that where you train, what sorts of patients you see, really shape your viewpoint and thinking about the disease process and the management process. [34:24] Dr. Kuang says she was so lucky to have experienced that at a quaternary care referral center like the NIH and at an academic center like Northwestern, where there are fantastic gastroenterologists who see so many of these patients. [34:56] Dr. Kuang and an Allergy Fellow knew they were going to get a wonderful data set from the NIH patients they had recruited, so they thought they had better look deeply at what had been learned before with older technology, with mice and people. [35:13] They decided to gather previous research, and that ultimately got published as an article. From that research, they learned that people did things in many different ways because there was no standard. They didn't know what the standard should be. [35:28] Different things you do to try to get eosinophils out of tissue impact how they look, in terms of transcript, gene expression, and what messages they make to define themselves as an eosinophil. [35:43] They also learned that because eosinophils are hard to work with, they die easily, and you can't freeze them and work on them the next day; you can introduce issues in there that have to be accounted for. [35:59] They learned that as an eosinophil research community, they ought to come up with some standards so that they can compare future studies with each other. Dr. Kuang says it was impossible to compare the old studies that used different premises. [36:50] Dr. Kuang says we need to be proactive in creating the datasets in a standard way so that we can compare and have a more fruitful and diverse community of data. It's hard to use the old data. [37:57] Dr. Kuang says they get fresh blood from patients, and because eosinophils are finicky, they need to be analyzed within four hours, or preserved in a way to save whatever fragile molecules are to be studied. [38:19] If you let it sit, it starts dying, so you won't have as many of them, and they start changing because they're not in the body. Dr. Kuang experimented with putting a tube of blood on the bench and checking it with the same test every two hours. It changes. [38:38] Four hours is a standard to prevent the eosinophils from dying. Patients need treatment. If a patient is hospitalized and needs treatment, Dr. Kuang's team needs to be there to get a sample before treatment is started. [39:03] The treatment impacts it, changing the situation. Much of the treatment, initially, is steroids. When you give lots of steroids, the eosinophils go away. It's no good to draw their blood then. [39:27] Dr. Kuang also gets a urine sample. The granules of the eosinophils can get into the urine. As they study people with active disease, they want to capture granule proteins in the urine as a less invasive way to monitor activity in different disease states. [40:04] The patient just needs to give Dr. Kuang either arm and a urine sample. [41:04] Dr. Kuang explains, you can count your eosinophils after four hours, but to study them, they have different flags of different colors and shapes. Those colors and shapes may mean that it's an activated eosinophil, or they may have other meanings. [41:41] Dr. Kuang focused on markers that look at whether it's going to spill its granules and some traditional markers of activation. [41:50] Everyone chooses a different marker of activation. So they decided to look at as many as they could. One marker is not sufficient. They seem to be different in different conditions. The markers are on the surface; you need to analyze them right away. [42:20] Then, Dr. Kuang breaks open the eosinophils and grabs the messenger RNA. They preserve it to do sequencing to read out the orders to see what this eosinophil is telling itself to make. RNA chops up messages. [43:00] When you open an eosinophil, a protein you find is RNA, which chops up messages, destroying parts of the cell. You want to save the message. There's a brief time to analyze the eosinophil. Dr. Kuang works to preserve and read the message. [44:04] Dr. Kuang hopes someday to run a tube of blood, look at the flags on the eosinophils, and say, "I think your eosinophilic GI disease is active," or "You have a kind of eosinophilic GI disease we need to monitor more frequently for organ damage." [44:38] If another patient doesn't have those flags, Dr. Kuang could say, "I think the chances that you're going to have involvement elsewhere are low." That can give reassurance to folks who are worried. [45:15] Dr. Kuang hopes that someday we can understand better why some people have food allergies vs. eosinophilic GI disease. They both have T cells, but the T cells have different packages inside with messages to deliver. [45:34] Every day, Dr. Kuang has to tell patients she doesn't have that answer. Someday, she hopes she can tell a patient she does have that answer. [46:35] Dr. Kuang tells about an NIH grant she's excited about and the patients she recruits after therapy, or elimination diets, to examine eosinophils and T cells, to see the impacts their treatments or diets have had on eosinophilic GI disease. [47:18] Dr. Kuang believes there will be predictors of who will respond to an elimination diet and who will respond to steroid therapy. She hopes one day to have that, rather than going through rounds of six to eight weeks followed by a scope. [47:34] If you have an elimination diet for six to eight weeks, every time you add back a food, you have to do a scope. Dr. Kuang says it would be great if you could be more precise ahead of time for therapy. [47:48] Dr. Kuang says these wonderful drugs selectively take out parts of the pathway in the immune system. They provide real-life opportunities to ask, why is this important in human biology and the human immune system? [48:15] Dr. Kuang finds the knowledge itself fascinating and useful. She hopes it informs how we choose future drugs or therapeutic avenues to get the best we can out of what we've learned, so we have more targeted ways of treating specific diseases. [48:48] Ryan is grateful for all the research happening for the eosinophilic disease community and all the patients participating in the research. He asks Dr. Kuang how a patient can participate in research. [49:12] There are lots of ways to be involved in research. Dr. Kuang says her patients come away from participating in research feeling good about having done it. [49:22] Answer a survey, if that's what you have bandwidth for. Where therapies are changing, being a part of a community is good for the community, for the future, but it's good for you, too. It's healing in ways that are not steroids or biologics. [49:58] Being part of a community is healing in ways we all need when we feel alone and bewildered. You're not alone. [50:12] There are many ways to participate: APFED, CEGIR, individual institutions, and clinical trials. They all have different amounts of involvement. It's worthwhile to participate, not only for future patients but for yourself. They're fantastic! [50:56] Dr. Kuang talks about the privilege as a physician of working with APFED and other organizations to do this work. [51:09] Holly thanks Dr. Kuang for sharing all of this research and exciting information. [51:25] Dr. Kuang is excited about what her group is doing and is hopeful. Besides showing up for this disease, we have to show up for research, in general, in this country. It's a dark time for NIH research funding. [51:55] Dr. Kuang asks the young listeners who are thinking of choosing a field to see the potential and get into it, study this, and believe that there's going to be a future with a more nurturing research environment. [52:36] Dr. Kuang would hate to lose generations of scientists. She says that once she was a little girl who was trying to be a scientist. Her parents had no connections with scientists or doctors, but she was able to get into research, and she thinks you can, too. [53:48] As a graduate student, Ryan has always been interested in trying to improve things, and he sees hope on the horizon. He's very grateful to the APFED community for supporting these research HOPE Pilot Grants. [54:17] Ryan is very grateful to Dr. Kuang for joining us today. [54:22] For our listeners who want to learn more about eosinophilic disorders, we encourage you to visit apfed.org and check out the links in the show notes. [54:28] If you're looking to find a specialist who treats eosinophilic disorders, we encourage you to use APFED's Specialist Finder at apfed.org/specialist. [54:37] If you'd like to connect with others impacted by eosinophilic diseases, please join APFED's online community on the Inspire Network at apfed.org/connections. [54:57] Dr. Kuang thanks Ryan and Holly and says she enjoyed the conversation. Holly also thanks APFED's Education Partners GSK, Sanofi, Regeneron, and Takeda for supporting this episode. Mentioned in This Episode: Fei Li Kuang, MD, PhD, Allergist and Immunologist, Northwestern Medicine Grants and publications discussed: Apfed.org/blog/apfed-announces-2018-hope-apfed-hope-pilot-grant-recipient/ Apfed.org/blog/fei-li-kuang-hope-pilot-grant-award/ Pubmed.ncbi.nlm.nih.gov/39213186/ Pubmed.ncbi.nlm.nih.gov/37487654/ APFED on YouTube, Twitter, Facebook, Pinterest, Instagram Real Talk: Eosinophilic Diseases Podcast apfed.org/specialist apfed.org/connections apfed.org/research/clinical-trials Education Partners: This episode of APFED's podcast is brought to you thanks to the support of GSK, Sanofi, Regeneron, and Takeda. Tweetables: "I think the patients that you meet in a clinical trial, especially in a special place like NIH, occupy a space in your heart — I don't mean to be all too emotional about this — that makes you want to keep working on the subject area." — Fei Li Kuang, MD, PhD "When I was a Fellow at the NIH, we were doing a Phase 2 clinical trial, looking at, for want of a better word, "blowing up" eosinophils in patients who have a lot of them, hypereosinophilic syndrome patients." — Fei Li Kuang, MD, PhD "We're at a point where we've recruited a lot of people. I've had patients drive from the northern part of Illinois … come down and give me blood. It's amazing what people want to do and are willing to do. It's very humbling, actually." — Fei Li Kuang, MD, PhD "You erase the eosinophils from the picture, but that message is still coming. Who's carrying out the orders? Or is that message maintaining the wall of epithelial cells in a certain way that we didn't appreciate because the eosinophils were also there?" — Fei Li Kuang, MD, PhD "We need to be proactive in creating the datasets in a standard way so that we can compare and have a more fruitful and diverse community of data." — Fei Li Kuang, MD, PhD "I think it's worthwhile to participate [in a clinical trial], not only for the future people but for yourself." — Fei Li Kuang, MD, PhD Guest Bio: Fei Li Kuang, MD, PhD, is currently an Assistant Professor in the Division of Allergy and Immunology at Northwestern University Feinberg School of Medicine in Chicago, IL. She is a graduate of the Albert Einstein College of Medicine Medical Scientist Training Program with both a PhD in Cell Biology/Immunology and an MD. She completed her Internal Medicine Residency at Columbia University, New York Presbyterian Hospital in New York City, she did her Fellowship in Allergy and Immunology at the National Institute of Allergy and Infectious Disease (NIAID) in Bethesda, Maryland. She is a physician-scientist who takes care of patients with eosinophilic disorders and also performs laboratory research on these disorders in her lab, often using patient samples.
This broadcast, I speak about how waiting can disrupt your flow, your energy and your momentum in life. It is based on a biblical story about the man at the pool of Bethesda who had been waiting for 38 years for someone to put him into the water to be healed.
Estas son las noticias del cine, series y cultura pop que no te puedes perder.
Ray, Jess and Andrew dig into the 2nd batch of New Vegas feedback from Wil, Suliore, Rando, Jeff, Calm Horizons, Mr Sullivan, Vanessa, Lee and Kos1moModus Files Series Retrospectivehttps://www.youtube.com/watch?v=mR9it4BgguQJoin our Discord:https://discord.gg/cVSN65jJoin in the Roundtable Fun with our Character Generators!Fallout 76: https://tinyurl.com/F76GeneratorFallout 4: https://tinyurl.com/Fallout4GeneratorFallout New Vegas: https://tinyurl.com/NewVegasGeneratorFallout 3: https://tinyurl.com/F3GeneratorThe NEW New Vegas Character Generator! DONATE: https://fightcf.cff.org/site/TR/?fr_id=7889&pg=team&team_id=90760Shop: optimistic.threadless.com/Patreon: https://www.patreon.com/asapodcastingEmail: thefalloutfeed@gmail.comWeb: http://www.asapodcasting.com/#/the-fallout-feed/Twitter: https://twitter.com/TheFalloutFeedFB: facebook.com/groups/askyrimaddictpodcastSupport the show
Evil Hat Productions has opened submissions for new role-playing games, with a primary focus on titles that utilize the Powered by the Apocalypse, Forged in the Dark, or Powered by Fate systems. They are specifically not publishing 5E material. The company is looking for complete or near-complete game manuscripts between 40,000 and 100,000 words that align with the Evil Hat product lines. They offer full publisher services, including editing, art direction, and public playtesting, and are seeking partners in marketing. Pitches should include a short game description, target audience, setting/tone details, mechanics, and development progress, and should be emailed to submissions@evilhat.com. Paizo has unveiled *Starfinder Galactic Ancestries*, an upcoming 224-page rulebook for *Starfinder Second Edition*, scheduled for release in April 2026 at an MSRP of $69.95. This expansion will introduce 21 brand new playable alien ancestries, such as the worlanisi, bantrid, and novian, alongside expanded options for existing Starfinder species like Vesk and Shirren. The book also provides Starfinder updates for classic fantasy ancestries including elves, gnomes, and goblins. Additionally, it features the Gap-touched versatile heritage and the xenometric android, allowing players to create robotic versions of any Starfinder alien or human. A new official Cyberpunk 2077 trading card game, titled *Cyberpunk TCG*, has been announced by CD Projekt Red and Weird Co. A hype trailer was released on December 9th, coinciding with the fifth anniversary of *Cyberpunk 2077*. The game will draw heavily on the aesthetics and characters of both *Cyberpunk 2077* and the *Cyberpunk: Edgerunners* anime, featuring Legends like Jackie Welles and Judy Alvarez, as well as V and Johnny Silverhand. Developed by a team with experience on games like *Marvel Snap* and *Universus*, the TCG is designed to be accessible to new players while offering depth for enthusiasts, with a crowdfunding campaign slated for 2026. A massive month-long sale is currently running on DriveThruRPG for the *Fallout RPG* line from Modiphius. Customers can save 33% on nearly every title, including the 438-page Core Rulebook, which uses the 2d20 cinematic roleplaying system and draws lore primarily from the Bethesda video games, particularly *Fallout 4*. The sale is an opportunity to acquire core books and expansions, such as the *Gamemaster's Toolkit*, the *Winter of Atom* campaign, or the *Wanderer's Guide Book*. Free Quickstart rules are also available for newcomers. #evilhat #starfinder #cyberpunkTCG #falloutrpg Evil Hat Game Submissions: https://evilhat.com/game-submissions/ Fallout RPG Sale: https://www.drivethrurpg.com/ja/product/366742/fallout-the-roleplaying-game-core-rulebook-pdf?affiliate_id=2081746 Free Guild Ball Starter Set: https://steamforged.com/products/guild-ball-starter-kit Warmachine on MyMiniFactory: https://mmf.io/upturned Mantic Companion App: https://companion.manticgames.com/ Use our Referral code: MCTXEE Support us by Shopping at Miniature Market (afilliate link): https://miniature-market.sjv.io/K0yj7n Support Us by Shopping on DTRPG (afilliate link): https://www.drivethrurpg.com?affiliate_id=2081746 Matt’s DriveThruRPG Publications: https://www.drivethrurpg.com/browse.php?author=Matthew%20Robinson https://substack.com/@matthewrobinson3 Chris on social media: https://hyvemynd.itch.io/ Abusecartoons Weekly Cartoons: http://www.abusecartoons.com/ https://www.twitch.tv/abusecartoons Support Us on Patreon: https://www.patreon.com/upturnedtable Give us a tip on our livestream: https://streamlabs.com/upturnedtabletop/tip Donate or give us a tip on Paypal: https://www.paypal.com/ncp/payment/2754JZFW2QZU4 Intro song is “Chips” by KokoroNoMe https://kokoronome.bandcamp.com/
The mental unraveling of a canine co-host accents this largely video game-related installment of Hardly Focused! Jack and Nate express bewilderment at both Metroid Prime 4's heavily anticipated launch, and the announcement of yet another Skyrim re-release. Not owning a Switch 2, this might be the first time Jack isn't buying another version of Bethesda's legendary dragon-taming simulator. Also discussed in this episode of Hardly Focused: Jack and Nate share horror stories about working in retail. How can one possibly screw up a relationship with Hayley Williams? GameStop's "trade anything" day is a huge success, with people bringing in things like taxidermized animals, cans of "whoop ass," and the Declaration of Independence. FOLLOW and SUBSCRIBE! https://hardlyfocused.com/subscribe Learn more about your ad choices. Visit megaphone.fm/adchoices
Teague travels to Bethesda, Maryland, to sit down with Leslie D. Hale, President and CEO of RLJ Lodging Trust. A Howard University alum with an early passion for finance, Leslie built her career driven by a desire to be on the decision-making side of the table—and today leads one of the industry's most respected public lodging companies. As the first African American woman to lead a publicly traded REIT, Leslie shares how her strategic mindset and appetite for calculated risks have shaped RLJ's evolution. With a portfolio of 96 hotels across 23 states—totaling approximately 21,000 rooms—she discusses the company's focus on urban lifestyle assets that thrive in “live, work, play” destinations. From active dispositions to reinvesting through renovations and conversions, Leslie calls this “the best portfolio the company has ever owned.” She opens up about the power of mentorship, the value of diverse perspectives in leadership, and the art of balancing professional ambition with family—reminding us that success often means being comfortable without having it all figured out.
Нужные лучшие новости про технологии и игры, самые интересные слухи, нечего смотреть или не понимаете во что играть – Завтракаст поможет вам. Уже десять лет трое ведущих Дима, Тимур и Максим помогают десяткам тысяч слушателей и зрителей в этом нелегком деле. Вы на пробежке? Едете на работу? Завтракаете? Неважно, трое виртуальных друзей скрасят ваш день диванным экспертным мнением и веселыми шутками (слегка кринжеватыми, но что поделать).
With days before The Game Awards, we're in a weird limbo of game announcements, but not to worry as we have plenty of fun games to discuss! But first, a movie based on a game: Five Nights at Freddy's. Next, Jocelyn completes her adventures in Clair Obscur: Expedition 33 in preparation for our own GOTY episode. Finally in what we're playing, Ryan shares his thoughts on Constance, a new metroidvania with some very welcome accessibility options. Over in the news, Bad Robot Game Studios is partnering with Sony for their game, Bethesda finds YET ANOTHER platform to release Skyrim on, and Netflix hand waves away the game studios as part of their acquisition plans for Warner Bros.Discussion00:00:00 - Five Nights at Freddy's Movie00:22:21 - Clair Obscur: Expedition 3300:38:46 - Constance00:55:26 - NewsExtra Life is back! Check out the team or donate by going to tiny.cc/tgiextralife.Important StuffSupport us on PatreonDiscord ChannelEmail the show Hosted on Acast. See acast.com/privacy for more information.
Ray, Jess, and Andrew tackle Come Fly with Me and Boulder City Showdown, plus some juicy Iguana Bits, gameplay, and lots of Fallout: New Vegas talkModus Files Series Retrospectivehttps://www.youtube.com/watch?v=mR9it4BgguQJoin our Discord:https://discord.gg/cVSN65jJoin in the Roundtable Fun with our Character Generators!Fallout 76: https://tinyurl.com/F76GeneratorFallout 4: https://tinyurl.com/Fallout4GeneratorFallout New Vegas: https://tinyurl.com/NewVegasGeneratorFallout 3: https://tinyurl.com/F3GeneratorThe NEW New Vegas Character Generator! DONATE: https://fightcf.cff.org/site/TR/?fr_id=7889&pg=team&team_id=90760Shop: optimistic.threadless.com/Patreon: https://www.patreon.com/asapodcastingEmail: thefalloutfeed@gmail.comWeb: http://www.asapodcasting.com/#/the-fallout-feed/Twitter: https://twitter.com/TheFalloutFeedFB: facebook.com/groups/askyrimaddictpodcastSupport the show
CLICK HERE! To send us a message! Ask us a Question or just let us know what you think!The autopsy reads like a military operation. The brain goes missing. From the first minutes on the tarmac to the last page of the Warren Commission, the JFK story is stitched with contradictions that refuse to die. We brought our roundtable back together to follow the hard edges: the casket swap accounts from Bethesda, morgue staff who recall a body bag and pre-autopsy surgery, and the chain-of-evidence gaps around the so‑called magic bullet. If a first-year defense attorney could dismantle the case, why did the nation accept it?We dig into the operational backdrop most people never see: JM/WAVE's web of CIA officers, anti-Castro exiles, and mob figures forged in the struggle against Castro; Operation Northwoods, which proved false flags were not fantasy but policy; and the rush to paint Oswald as a Cuban- and Soviet-linked agent via New Orleans leafleting, Mexico City legends, and convenient IDs. We weigh Lyndon Johnson's choices—why the Cuba blame was abandoned, how Vietnam escalated immediately, and what his behavior in Dealey Plaza and on Air Force One might tell us. Along the way, names like E. Howard Hunt and Curtis LeMay surface, tying Dallas to a broader culture of covert power and political pressure.This isn't a hunt for every shooter. It's a search for the employers—the coalition with the reach to manage an autopsy, redirect the press, and outlast oversight. We revisit Parkland doctors' accounts of the head wound, explore the “Prayer Man” doorway footage that could upend the sixth-floor narrative, and confront the witness attrition that shadows the case. If you care about the integrity of evidence, the architecture of cover stories, and how national security can bend truth, you'll want to hear this unvarnished exchange.If this conversation moves you, follow the show, share it with a friend who still has questions about Dallas, and leave a review telling us what piece of evidence you think matters most. Your take might guide our next deep dive.
Podcasting. Podcasting never changes. Except for all the times we break from "Trek" to talk about something else, which we're doing again to discuss "Fallout" season one! With the second season just around the corner, we're talking the very successful video game adaptation that brought Interplay and Bethesda's (and to some extent Obsidian's) wasteland to a wider audience. There's Ghouls, Vault Dwellers, and Power Armor, so pull up whatever bit of pre-war trash counts as a seat around here and listen in! Also this week: hot zombies, cold villains, and chilling motivations!
Müssen wir wirklich bis 2031 auf Fallout 5 warten? Host Felix diskutiert mit den Experten Tillmann und Valentin, ob die legendäre Endzeit-Reihe ihre Seele verloren hat oder durch die Amazon-Serie gerade erst wiedergeboren wird. Wir analysieren knallhart, was Bethesda bei Fallout 4 & 76 versäumt hat und werten eure Community-Umfrage aus: Was muss Teil 5 bieten, um die Fans zu retten – Fahrzeuge, Multiplayer oder endlich wieder tiefgründige RPG-Mechaniken?
Well, here we are. The UX Strategy and Leadership course has wrapped up, and I am officially putting down my digital pen until January 8th.I know. Try not to weep.
Ever worry about finding yourself in a civil or criminal case as a result of your actions as a nurse? Join the co-hosts as they welcome Attorney Rachel Giles to help us demystify nursing legal liability, including must-dos, don't-dos, and real-world pitfalls so you can protect your license, your patients, and your peace of mind. (AMSN Members Earn 0.5 CE Hours*) * This episode is eligible for 0.5 contact hours for AMSN members who listen to the episode and submit a completed evaluation through the online library. None of the individuals with the ability to control the content of this episode have any relevant financial relationships with ineligible companies to disclose. The Academy of Medical Surgical Nurses is an accredited provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. SPECIAL GUEST Rachel Giles, JD, MBA/MHA is a United States Army Veteran, brings over a decade of experience in health law, compliance, federal regulations, and risk management. She is dedicated to delivering innovative conflict resolution, consulting, education, and knowledge, leveraging her unique expertise to help clients and healthcare organizations navigate complex challenges in both legal and operational environments. Rachel is passionate about fostering effective communication and equitable solutions to ensure that every person feels safe and empowered to move forward confidently. Rachel's professional experience includes serving as CEO of Giles Mediation, LLC., where she assist low socioeconomic status clients mediate cases in an attempt to stay out of a long costly court battle. She was the Vice President of Compliance & Administration for AshtonBridge Capital, where she implemented risk management frameworks and compliance protocols across diverse industries such as investment, real estate, and commodity trading. Additionally, her tenure in senior roles at multiple Healthcare Organizations within the Texas Medical Center in Houston highlights her skill in mitigating risks, conducting audits, and driving quality and patient safety improvement initiatives. She is adept at contract negotiation, policy development, and litigation support, making her a trusted advisor to organizations. Academically, Rachel holds a Doctorate in Law with a specialization in Compliance, Regulatory Affairs, and Risk Management, alongside dual master's degrees in Business and Health Administration. Her credentials are complemented by certifications in Lean Six Sigma, Project Management, and Mediation. She was recognized for academic excellence, including achieving top marks in cybersecurity coursework, where she developed actionable strategies for addressing HIPAA data breaches. Her ability to merge research with practical application has been a hallmark of her professional and academic career. MEET OUR CO-HOSTS Samantha Bayne, MSN, RN, CMSRN, NPD-BC is a nursing professional development practitioner in the inland northwest specializing in medical-surgical nursing. The first four years of her practice were spent bedside on a busy ortho/neuro unit where she found her passion for newly graduated RNs, interdisciplinary collaboration, and professional governance. Sam is an unwavering advocate for medical-surgical nursing as a specialty and enjoys helping nurses prepare for specialty certification. Kellye' McRae, MSN-Ed, RN is a dedicated Med-Surg Staff Nurse and Unit Based Educator based in South Georgia, with 12 years of invaluable nursing experience. She is passionate about mentoring new nurses, sharing her clinical wisdom to empower the next generation of nurses. Kellye' excels in bedside teaching, blending hands-on training with compassionate patient care to ensure both nurses and patients thrive. Her commitment to education and excellence makes her a cornerstone of her healthcare team. Marcela Salcedo, RN, BSN is a Floatpool nightshift nurse in the Chicagoland area, specializing in step-down and medical-surgical care. A member of AMSN and the Hektoen Nurses, she combines her passion for nursing with the healing power of the arts and humanities. As a mother of four, Marcela is reigniting her passion for nursing by embracing the chaos of caregiving, fostering personal growth, and building meaningful connections that inspire her work. Eric Torres, ADN, RN, CMSRN is a California native that has always dreamed of seeing the World, and when that didn't work out, he set his sights on nursing. Eric is beyond excited to be joining the AMSN podcast and having a chance to share his stories and experiences of being a bedside medical-surgical nurse. Maritess M. Quinto, DNP, RN, NPD-BC, CMSRN is a clinical educator currently leading a team of educators who is passionately helping healthcare colleagues, especially newly graduate nurses. She was born and raised in the Philippines and immigrated to the United States with her family in Florida. Her family of seven (three girls and two boys with her husband who is also a Registered Nurse) loves to travel, especially to Disney World. She loves to share her experiences about parenting, travelling, and, of course, nursing! Sydney Wall, RN, BSN, CMSRN has been a med surg nurse for 5 years. After graduating from the University of Rhode Island in 2019, Sydney commissioned into the Navy and began her nursing career working on a cardiac/telemetry unit in Bethesda, Maryland. Currently she is stationed overseas, providing care for service members and their families. During her free time, she enjoys martial arts and traveling.
It belongs in a museum! On this episode of The Movie Podcast, Troy Baker returns to the show alongside MachineGames Creative Director Axel Torvenius to celebrate the 1 Year Anniversary release of Indiana Jones and The Great Circle. Set after Raiders of the Lost Ark, Indiana Jones embarks on a globe-spanning adventure—from Vatican City to the Giza pyramids and Sukhothai—to stop rival groups from harnessing the power of the Great Circle, a network of mysterious sites forming a perfect circle around the world. Indiana Jones and the Great Circle is now available on Xbox Series X|S, PC, and PlayStation 5, and coming to Nintendo Switch 2 in 2026. Watch and listen to The Movie Podcast now on all podcast platforms, YouTube, and TheMoviePodcast.ca Contact: hello@themoviepodcast.ca FOLLOW US Daniel on X, Instagram, Letterboxd Shahbaz on X, Instagram, and Letterboxd Anthony on X, Instagram, and Letterboxd The Movie Podcast on X, Instagram, TikTok, Discord, and Rotten Tomatoes Learn more about your ad choices. Visit megaphone.fm/adchoices
Hosted by David and Nycci Nellis. On today's show:· The SNAP mess created during the recent government shutdown threatened 40 million Americans – among them, 16 million kids – with the loss of desperately needed funding for food. Food they count on for survival. Hunger across America – and across the DC area – remains a challenge. Radha Muthiah is the president and CEO of the Capital Area Food Bank. She joins us for an update on the ongoing problem; · Former White House pastry chef Susan Limb is co-owner of the Praline Bakery & Bistro in Bethesda and at The Wharf. She's celebrating Praline's 20th anniversary in April -- and we're going to do the run-up celebration today; · Greg Engert – globally famous partner and beer director at NRG – on ways to give during the holidays; · Chris Powers, partner/owner at the Juneberry Garage, a tavern-style bar and restaurant in The Parks at Walter Reed; · Eric Lawson, director of food and beverage for the Singing Tiger, the new restaurant and bar recently opened in the lower level of the Hotel Nell in the Union Market District.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Jacqueline Ackerman is Director of the Women's Philanthropy Institute (WPI) at the Indiana University Lilly Family School of Philanthropy. WPI believes that gender matters in philanthropy, and that solving the world's complex problems requires perspective, leadership and generosity from women and men. Jacqueline's work centers on moving the institute's research into action, delivering insights to donors, fundraisers and sector leaders that grow women's giving and deepen fundraisers' engagements with female donors. Over the last decade, Jacqueline has led WPI's research agenda, including serving as primary author on most of WPI's research reports. Jacqueline joined the Lilly Family School of Philanthropy in 2012 after earning a Master of Public Affairs from the Indiana University O'Neill School of Public and Environmental Affairs in Bloomington. She was raised in Port-au-Prince, Haiti, and resides in Bethesda, MD. To learn more about Jacqueline Ackerman and Women's Philanthropy Institute: https://www.linkedin.com/in/jacquelineackerman https://www.instagram.com/womensphilanthropy https://www.facebook.com/womensphilanthropyinstitute https://www.linkedin.com/company/womensphilanthropy
Editor in Chief Cecelia E. Schmalbach, MD, MSc, is joined by senior author John P. Dahl, MD, PhD, MBA, and Associate Editor Marissa Ryan, MD, to discuss their findings in "TI-RADS and Bethesda Classification System Correlate With Predicting Pediatric Papillary Thyroid Carcinoma," which was published in the October 2025 issue of Otolaryngology–Head and Neck Surgery. Click here to read the full article.
Garth Heckman The David Alliance TDAgiantSlayer@Gmail.com Psalm 9:1-2: "I will give thanks to the Lord with my whole heart; I will recount all of your wonderful deeds” It says give thanks with your heart, NOT YOUR HEAD OR MIND. **This verse is in the context of Davids enemies coming to get him. ??? What does he do he gives thanks and pulls the video of all the times God came through in the past! Recount/play the video - I should have died or been paralyzed when I broke my neck - I was unjustly fired from a job and it opened the door to a better job 3 minutes from college - I was asked to prophecy over 70 college students How many people talk about having an out of body experience… thats easy - give thanks. Your body your mind does not want to give thanks - IT DOESN'T WANT TO BELIVE GOD WILL DO SOMETHING AMAZING. It has to come from your spirit… your heart. When did the children of Israel make the golden calf? Waiting on Moses… they were unable to step out of the flesh and into the spirit… so they acted out on their own. Abraham and Sarah - sleep with Hagar…= Ishmael King Saul waiting for the Prophet Samuel… makes a sacrifice waiting and God rejects him. UNLIKE IN JOHN 6 - there are over 10K people hungry. The disciples want to send them away… The disciples… learned to think…”you never know” The storm… The 2 fish and five loaves John 6:1-15 Jesus asks Phillip where we could get food. Because Phillip was from Bethesda the nearest town… he wanted to make a point of human wisdom, critical thinking and problem solving with simple trust in God and his power.
Jess and Ray listen to some fantastic Fallout New Vegas feedback from our listeners as they embark into the Mojave Wasteland. Plus Burning Springs, Fallout 4 patches, and moreThe NEW New Vegas Character Generator! Listen to the show to learn more, it should be ready to go!Modus Files Series Retrospectivehttps://www.youtube.com/watch?v=mR9it4BgguQJoin our Discord:https://discord.gg/cVSN65jJoin in the Roundtable Fun with our Character Generators!Fallout 76: https://tinyurl.com/F76GeneratorFallout 4: https://tinyurl.com/Fallout4GeneratorFallout New Vegas: https://tinyurl.com/NewVegasGeneratorFallout 3: https://tinyurl.com/F3GeneratorDONATE: https://fightcf.cff.org/site/TR/?fr_id=7889&pg=team&team_id=90760Shop: optimistic.threadless.com/Patreon: https://www.patreon.com/asapodcastingEmail: thefalloutfeed@gmail.comWeb: http://www.asapodcasting.com/#/the-fallout-feed/Twitter: https://twitter.com/TheFalloutFeedFB: facebook.com/groups/askyrimaddictpodcastSupport the show
The sermon centers on the transformative question, 'Wilt thou be made whole?', drawing from John 5:1–9 to confront the spiritual complacency of believers who, like the man at Bethesda, remain passive despite divine opportunity. It emphasizes that while God offers healing, power, and community, true restoration requires personal responsibility, obedience, and a willingness to move beyond self-justification and blame. The preacher underscores the danger of spiritual stagnation—rooted in bitterness, sympathy, or cultural distractions—arguing that Christians must actively engage with Scripture, the church, and the Holy Spirit to grow beyond long-term infirmities. Drawing from Romans 8, Galatians 6, and Ephesians 4, the message calls for a deliberate choice to walk in the Spirit, mortify the flesh, and bear one another's burdens not through dependency, but through mutual accountability and grace. Ultimately, the sermon is a pastoral challenge to embrace spiritual maturity, reject passive waiting, and step forward in faith, knowing that God's power is available to those who are willing to be made whole.
The torture and murder of 30-year-old Jayna Murray inside the Lululemon store shocked the affluent community of Bethesda, Maryland. But was the rape of her colleague Brittany Norwood everything that it appeared to be? Police had to take a deep dive into betrayal, lies, fraud, and the "cult" of Lululemon to unveil a red collar psychopath.
Ever wondered what it's like to serve as a combat nurse on the front lines? Join us for this special Veterans Day episode with Colonel Susan Luz as she shares inspiring and heartbreaking stories of service, resilience, and leadership that translate from the battlefield to the bedside. SPECIAL GUEST Susan Luz, BSN, MPH, RN graduated from the University of Rhode Island with a degree in Nursing. After a clinical rotation at Rhode Island's Institute of Mental Health and public health experiences, she joined the Peace Corps, with her first assignment in Brazil. After leaving the Peace Corps, Luz earned her master's degree in public health nursing from Boston University. She returned to Brazil with Project Hope and then took a job as a nurse-teacher at Central High School in Providence and ran its school-based clinic from 1978 to 2006. While working at Central, she also worked nights at the state Institute of Mental Health and then Gateway Healthcare's Acute Residential Treatment Center. Luz joined the Army Reserves in 1983. She was 56 years old when her unit was later deployed to Iraq in 2006, at the height of the U.S. surge and the bloodiest point of the war. Colonel Luz was the highest-ranking woman in the 399th Combat Support Hospital, a Massachusetts based Army Reserve unit. As a public health nurse with certification as a psychiatric nurse, Luz's mission in Iraq included helping soldiers with emotional trauma, and providing comfort to dying soldiers. Luz formed her own "Band of Sisters," a group of nurses who were not only dedicated to treating wounded soldiers, but also maintaining morale among the troops, especially during the unit's time in the middle of the desert in Al Asad. Luz was awarded the Bronze Star in 2007. She is the author of "The Nightingale of Mosul" A Nurse's Journey of Service, Struggle, and War. MEET OUR CO-HOSTS Samantha Bayne, MSN, RN, CMSRN, NPD-BC is a nursing professional development practitioner in the inland northwest specializing in medical-surgical nursing. The first four years of her practice were spent bedside on a busy ortho/neuro unit where she found her passion for newly graduated RNs, interdisciplinary collaboration, and professional governance. Sam is an unwavering advocate for medical-surgical nursing as a specialty and enjoys helping nurses prepare for specialty certification. Kellye' McRae, MSN-Ed, RN is a dedicated Med-Surg Staff Nurse and Unit Based Educator based in South Georgia, with 12 years of invaluable nursing experience. She is passionate about mentoring new nurses, sharing her clinical wisdom to empower the next generation of nurses. Kellye' excels in bedside teaching, blending hands-on training with compassionate patient care to ensure both nurses and patients thrive. Her commitment to education and excellence makes her a cornerstone of her healthcare team. Marcela Salcedo, RN, BSN is a Floatpool nightshift nurse in the Chicagoland area, specializing in step-down and medical-surgical care. A member of AMSN and the Hektoen Nurses, she combines her passion for nursing with the healing power of the arts and humanities. As a mother of four, Marcela is reigniting her passion for nursing by embracing the chaos of caregiving, fostering personal growth, and building meaningful connections that inspire her work. Eric Torres, ADN, RN, CMSRN is a California native that has always dreamed of seeing the World, and when that didn't work out, he set his sights on nursing. Eric is beyond excited to be joining the AMSN podcast and having a chance to share his stories and experiences of being a bedside medical-surgical nurse. Maritess M. Quinto, DNP, RN, NPD-BC, CMSRN is a clinical educator currently leading a team of educators who is passionately helping healthcare colleagues, especially newly graduate nurses. She was born and raised in the Philippines and immigrated to the United States with her family in Florida. Her family of seven (three girls and two boys with her husband who is also a Registered Nurse) loves to travel, especially to Disney World. She loves to share her experiences about parenting, travelling, and, of course, nursing! Sydney Wall, RN, BSN, CMSRN has been a med surg nurse for 5 years. After graduating from the University of Rhode Island in 2019, Sydney commissioned into the Navy and began her nursing career working on a cardiac/telemetry unit in Bethesda, Maryland. Currently she is stationed overseas, providing care for service members and their families. During her free time, she enjoys martial arts and traveling.
Linktree: https://linktr.ee/AnalyticJoin The Normandy For Additional Bonus Audio And Visual Content For All Things Nme+! Join Here: https://ow.ly/msoH50WCu0KAnalytic Dreamz breaks down the highly anticipated official trailer for Fallout Season 2 on Prime Video in this new segment of Notorious Mass Effect. Dropping December 17, the trailer teases an even bigger, weirder, and more explosive return to the Wasteland with Ella Purnell reprising Lucy, Aaron Moten as Maximus, Walton Goggins stealing scenes as The Ghoul, and the post-apocalyptic chaos fans crave. Analytic Dreamz analyzes key moments, hidden Easter eggs from the Bethesda games, character arcs, potential Vault-Tec twists, and how Season 2 builds on the massive success of the first season. If you're counting down the days to re-enter the Fallout universe, this segment delivers in-depth reactions, lore connections, and honest takes on what Prime Video's adaptation has in store next.Support this podcast at — https://redcircle.com/analytic-dreamz-notorious-mass-effect/donationsPrivacy & Opt-Out: https://redcircle.com/privacy
Episode Summary: In this episode, Ed sits down with industry leader Kris Butterfield Cance to explore one of the most urgent challenges facing private clubs today: generational transition. From outdated bylaws to evolving member expectations, Kris breaks down what clubs must rethink if they want to stay relevant and financially healthy in the next decade. She shares practical examples from her work at Bethesda Country Club and La Cumbre Country Club, offering a front-row view of what successful evolution looks like. This conversation is a candid, realistic look at how clubs can honor legacy while creating space for the future. Key Moments: 3:20 — Why Kris wrote her Boardroom Magazine piece Kris explains the conversations and frustrations she heard at PCMA that inspired her to address generational stagnation head-on. 5:15 — What younger generations actually want from clubs From flexible programming to redefining tradition, Kris breaks down what Gen X, Y, and Z members value in club experiences. 7:55 — Balancing legacy expectations with modern needs Ed and Kris discuss how clubs can preserve tradition while adapting formats, events, and amenities. 10:05 — Community as the real differentiator A look at why everyday experiences—card rooms, family zones, outdoor gathering spaces—matter more than once-a-year blowout events. 12:25 — The financial urgency behind generational transition Kris and Ed dive into wait lists, initiation fee trends, and the wealth transfer that will shape clubs through 2045. 14:10 — How one traditional club successfully modernized Kris shares the transformation at Bethesda and how they rebalanced their member demographic. 17:50 — The importance of board clarity: mission, vision, values Kris explains why cultural alignment must start in the boardroom and how clubs can implement practical systems. 22:20 — Transparency without oversharing They unpack the difference between healthy transparency and giving members unnecessary or harmful detail. 26:55 — What data reveals about actual member behavior Kris explains how usage patterns—not just event attendance—should inform decision-making. 31:00 — Should younger families "skip the line"? Kris addresses the controversial question of whether clubs should prioritize young applicants over older prospects. 34:40 — Final takeaway: Relevance over replacement Kris closes with the core truth: clubs don't need to choose one generation over another; they need to stay relevant to all.
For thirty eight years a man lay unseen beside Bethesda's waters, until Jesus stepped through a crowd of broken people and found him. This sermon draws you into that moment, pointing to the God who enters our pain, exposes our religious pretense, and heals what no pool ever could. Come see why Jesus is the true “house of mercy.”
As was originally reported, Xbox brought out a Partner Preview in November. It was chockful of everything strange like a co-op alien shop simulator or a thuggish rabbit beating up baddies to more traditional first person horror titles. The catch was that every game we saw throughout was a Play Anywhere title, a program that many of Xbox's players still yearn for the platform to leverage more. All in all, the Dukes enjoyed the show, especially given it dropped ahead of the biggest show of the year in the Game Awards where announcements are typically prioritized. Beyond that, we dive deep into the Valve rumor mill. Half Life 3 is everywhere! Is it finally happening and are the Dukes believers? We get into that plus updated thoughts on the Steam Machine now that we've had some time to digest the triple-whammy Valve hit us with last week. Sign up for your one-dollar-per-month trial and start selling today at https://www.shopify.com/duke Please keep in mind that our timestamps are approximate, and will often be slightly off due to dynamic ad placement. 0:00:00 - Intro0:13:32 - Discussing The Game Awards nominees0:31:43 - The myriad of Half Life 3 rumors0:36:54 - Valve's focus for the Steam Machine0:51:16 - Xbox Ally is exceeding expectations0:55:09 - Xbox releases game publishing documentation to the public0:59:26 - Obsidian has yet to use generative AI1:03:17 - Activision caught using AI generated assets in Black Ops 71:12:01 - Bethesda responds to Fallout 4's anniversary issues1:28:04 - Krafton is now the publisher of Hi Fi Rush, but there's a catch1:31:37 - New comments by Sarah Bond on Xbox's future1:37:18 - PlayStation was indifferent to market shrinking in Japan1:46:07 - Where is Yoko Taro?1:48:58 - A new Ratchet & Clank game got revealed1:56:42 - Don't call it a Concord comeback2:00:35 - Silent Hill Townfall's release date leaked2:02:15 - Ubisoft canceled Splinter Cell for xDefiant2:10:02 - Red Dead Redemption 1 gets next gen update2:10:56 - Kingdom Come Deliverance 2 reaches 4 million sales figure2:13:38 - First look at Zelda movie2:14:27 - Death Stranding is getting an original anime on Disney+2:17:16 - Coming soon to Xbox Game Pass2:19:42 - What We've Been Playing3:11:50 - Xbox Partner Preview Learn more about your ad choices. Visit podcastchoices.com/adchoices
SUMMARY:In today's episode, Steph takes listeners deep into one of the most shocking workplace murders in recent history — the Lululemon case. This story follows the lives of Jayna Murray and Brittany Norwood, two women who started life on remarkably similar paths: athletic, ambitious, intelligent, and deeply loved. But as adulthood unfolded, their journeys diverged dramatically.Jayna lived a life full of adventure, discipline, and exploration — from her childhood in Australia to her graduate studies at Johns Hopkins. Brittany, once a standout soccer star with a promising future, quietly battled an impulse she never confronted: a cycle of compulsive stealing that grew more dangerous over time.On March 12, 2011, those two paths collided inside a Lululemon store in Bethesda, Maryland.Listeners will hear:Jayna's international upbringing, athletic excellence, academic brilliance, and deep devotion to her familyBrittany's competitive childhood, collegiate soccer career, and the long-standing pattern of theft that followed her into adulthoodA detailed breakdown of the crime scene and Brittany's initial account of the attackThe investigation's early focus on an unrelated suspect, Keith Lockett, and how detectives ultimately cleared himThe disturbing inconsistencies that led police to re-examine Brittany's storyThe emotional second interview, including the pivotal moment Brittany's brother confronted herThe psychological insight behind kleptomania—why the urge to steal can become an addictionThe truth about the altercation between Jayna and Brittany that nightHow Brittany staged the scene, lied, and ultimately confessedThe heartbreaking details of Jayna's injuries and the trial that followedThis episode explores:How compulsive behaviors, when left untreated, can escalate into tragedyThe consequences of avoidance, secrecy, and escalating bad choicesThe systemic failure of Lululemon to address repeated employee misconductHow confrontation — especially over conduct long hidden — can trigger catastrophic outcomesThe bravery of Jayna Murray and the life she deserved to continue livingSteph closes the episode with a powerful discussion on how we often trivialize stealing as harmless or childish — when in reality, it can become its own addiction cycle. Brittany's reluctance to get help or face consequences created a storm she could no longer outrun, and Jayna lost her life because of it. This tragedy stands as a reminder that ignoring patterns doesn't erase them… it allows them to grow.-----------------------------------------------------------------Giveaway Instructions Subscribe to the Murder in the Black YouTube channel.Choose any video on our channel and leave a comment.That's it — you're entered!The giveaway closes November 30th, so don't wait — jump in now!LINK BELOWhttps://youtube.com/@murderintheblack?si=cr03m4ITJTzz01qXSources for This Episode:The Washington Post – In-depth reporting on the Lululemon murder, trial transcripts, and investigative findings.ABC News – Coverage of Brittany Norwood's arrest, trial, and details surrounding theft allegations and motive.NBC Washington – Local reporting from 2011 including interviews, community statements, and crime-scene updates.The Baltimore Sun – Reporting on Brittany Norwood's confession, trial proceedings, and sentencing.Montgomery County Court Records – Trial filings, witness statements, and verdict documentation from State of Maryland v. Brittany Norwood
FOLLOW RICHARD Website: https://www.strangeplanet.ca YouTube: @strangeplanetradio Instagram: @richardsyrettstrangeplanet TikTok: @therealstrangeplanet EP. # 1282 JFK & the X-Rays that Shatter the Official Story November 22, 1963 wasn't the day democracy died—it was the day it was murdered in plain sight and autopsied with criminal fraud. Physicist Dr. David Mantik returns to Strange Planet with explosive New EVIDENCE - optical density measurements of the original JFK autopsy X-rays, proving beyond doubt that the president's head wounds were surgically altered on film before the body ever reached Bethesda. And, Cold War historian Walter Herbst reveals how the assassination wasn't chaos, but consensus policy born from covert operations and geopolitical necessity. This is the original Deep State “deep-fake”—forged evidence that still controls the narrative today. GUESTS: Dr. David Mantik, MD, PhD – A radiation oncologist and physicist who personally examined the JFK autopsy X-rays and photographs at the National Archives on nine separate occasions. Author of President John F. Kennedy: The Final Analysis, The JFK Assassination Decoded: Criminal Forgery in the Autopsy Photographs and X-Rays, and the groundbreaking new book JFK Was Killed by Consensus. His peer-reviewed optical density data proves the autopsy images were altered—making him the foremost forensic challenger to the official record. Walter Herbst – Cold War historian and author of the landmark two-volume series It Did Not Start With JFK, which traces the intelligence networks, propaganda machines, and Berlin/Cuba crises that made Kennedy's removal official—if unspoken—policy. His latest work, Last Resort Beyond Last Resort, exposes why the assassination guaranteed no second invasion of Cuba and protected NATO's flank in Berlin. Herbst doesn't peddle conspiracy theories; he documents the paper trail of the original Deep State in action. WEBSITES: https://www.facebook.com/WalterHerbstAuthor https://themantikview.org BOOKS: The Assassination of John F. Kennedy: The Finaly Analysis The JFK Assassination Decoded JFK was Killed by Consensus It Did Not Start with JFK Vols 1 & 2 Last Resort Beyond Last Resort SUPPORT OUR SPONSORS!!! FOUND – Smarter banking for your business Take back control of your business today. Open a Found account for FREE at Found dot com. That's F-O-U-N-D dot com. Found is a financial technology company, not a bank. Banking services are provided by Lead Bank, Member FDIC. Join the hundreds of thousands who've already streamlined their finances with Found. HIMS - Making Healthy and Happy Easy to Achieve Sexual Health, Hair Loss, Mental Health, Weight Management START YOUR FREE ONLINE VISIT TODAY - HIMS dot com slash STRANGE https://www.HIMS.com/strange MINT MOBILE Premium Wireless - $15 per month. No Stores. No Salespeople. JUST SAVINGS Ready to say yes to saying no? Make the switch at MINT MOBILE dot com slash STRANGEPLANET. That's MINT MOBILE dot com slash STRANGEPLANET BECOME A PREMIUM SUBSCRIBER!!! https://strangeplanet.supportingcast.fm Three monthly subscriptions to choose from. Commercial Free Listening, Bonus Episodes and a Subscription to my monthly newsletter, InnerSanctum. Visit https://strangeplanet.supportingcast.fm Use the discount code "Planet" to receive $5 OFF off any subscription. We and our partners use cookies to personalize your experience, to show you ads based on your interests, and for measurement and analytics purposes. By using our website and services, you agree to our use of cookies as described in our Cookie Policy. Learn more about your ad choices. Visit megaphone.fm/adchoices Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://strangeplanet.supportingcast.fm/
Ethan, Ketan & Raad, three amazing Bethesda hospice volunteers and aren't all holidays made up?- h2 full 2173 Wed, 19 Nov 2025 21:12:27 +0000 TarPL69ddXtWwaGBY7loHsPTDEJYhVt5 comedy,religion & spirituality,society & culture,news,government The Dave Glover Show comedy,religion & spirituality,society & culture,news,government Ethan, Ketan & Raad, three amazing Bethesda hospice volunteers and aren't all holidays made up?- h2 The Dave Glover Show has been driving St. Louis home for over 20 years. Unafraid to discuss virtually any topic, you'll hear Dave and crew's unique perspective on current events, news and politics, and anything and everything in between. © 2025 Audacy, Inc. Comedy Religion & Spirituality Society & Culture News Government False
The NEW New Vegas Character Generator! Listen to the show to learn more, it should be ready to go!Modus Files Series Retrospectivehttps://www.youtube.com/watch?v=mR9it4BgguQJoin our Discord:https://discord.gg/cVSN65jJoin in the Roundtable Fun with our Character Generators!Fallout 76: https://tinyurl.com/F76GeneratorFallout 4: https://tinyurl.com/Fallout4GeneratorFallout New Vegas: https://tinyurl.com/NewVegasGeneratorFallout 3: https://tinyurl.com/F3GeneratorDONATE: https://fightcf.cff.org/site/TR/?fr_id=7889&pg=team&team_id=90760Shop: optimistic.threadless.com/Patreon: https://www.patreon.com/asapodcastingEmail: thefalloutfeed@gmail.comWeb: http://www.asapodcasting.com/#/the-fallout-feed/Twitter: https://twitter.com/TheFalloutFeedFB: facebook.com/groups/askyrimaddictpodcastSupport the show
Feeling stressed? You're not alone! And that's exactly the point of this lively episode of Practical for Your Practice! Hosts Jenna Ermold and Carin Lefkowitz welcome back the always-animated (and self-proclaimed “gesturing Italian”) Dr. Gabriel Paoletti for a refreshingly human take on stress.From cheesesteaks to “mamma mia” stress cues, this conversation dives into how we can rethink stress, not as something to eliminate, but as a signal that something meaningful is at stake. Dr. Paoletti breaks down how stress can actually help performance, especially when we approach it as a shared experience, a “team sport”, instead of a solo battle.Tune in for practical strategies (and a few laughs) on how to build your “stress team,” use humor to stay grounded, and create simple cues that help you, and those around you, catch stress before it catches you.Bonus: Find out why “halloumi” might be the most unexpectedly perfect stress word ever.You can leave us a voice mail message at speakpipe.com/cdpp4p, or send us an email at cdp-podcast-ggg@usuhs.edu. Your message could be featured in an upcoming episode!Dr. Gabriel Paoletti is the Director of Human Performance Optimization (HPO) Integration and HPRC in support of the Advanced Research for Military Optimization, Readiness, and Rehabilitation (ARMORR) – Consortium for Health and Military Performance (CHAMP), a center at the Uniformed Services University in Bethesda, Maryland. He oversees the strategic and operational components of delivering comprehensive health and performance education on Total Force Fitness and Human Performance Optimization to the DoD and national security community. Over the past 15+ years, Dr. Paoletti has applied the latest human performance research to create and lead over 400 distinct human performance optimization and leadership development programs for audiences throughout the world, ranging from leaders at the Pentagon, Army, Marine, Air Force, Navy, Coast Guard service members to Fortune 500 companies, professional athletes, CEO's and government leaders. Under his leadership, his team has been officially selected to develop holistic human performance curricula for half of the U.S. Armed Forces. Dr. Gabriel Paoletti graduated from Saint Joseph's University with a double major in economics and philosophy, graduating first in his class in both majors. He received his Master of Applied Positive Psychology from the University of Pennsylvania and his Doctor of Education in Leadership from Creighton University.Resources mentioned in this episode: https://www.hprc-online.org/mental-fitness/stress/unlock-your-full-potential-hprcs-personal-stress-toolkithttps://www.hprc-online.org/mental-fitness/mental-health/build-your-stress-team Calls-to-action: For example:Identify who is on YOUR stress teamReview the resources from HPRCSubscribe to the Practical for Your Practice PodcastSubscribe to The Center for Deployment Psychology Monthly Email Leave us a question or comment on Speakpipe
This week for Episode 196 Jeremy, Stephen, & Chase talk about Sony's State of Play Japan highlights, Steams new hardware lineup announcements, the Pokopia Key-Card news, Super Mario Galaxy Direct, previews panic over a talking character in Metroid Prime 4 Beyond, Black Ops 7 is filled with AI slop, Hi-Fi Rush publishing transfer, Krafton calls for "voluntary resignations" while they replace the people with AI, & more! Our "Big Question" for this week is "With the holiday shopping season coming up soon, what are a few of our favorite gaming accessories we would recommend for others wanting to get a gift for a loved one (or just for themselves)?" Check out the video version of the podcast over at www.youtube.com/zenspathcom, share it with friends, give us a thumbs up, & leave us a review if you enjoy the show to help us grow! Website - https://www.zenspath.com Podcast Website - https://www.zenspath.com/podcast Join our Discord - https://discord.com/invite/jsB8GURSvT ( bit.ly/zenspathdiscord ) Apple Podcasts - https://apple.co/3scFDqv Spotify - https://open.spotify.com/show/2nFegSJNWR0na1BAv6AOSD Libsyn - https://zenspath.libsyn.com/2024/02 Amazon Music - https://music.amazon.com/podcasts/08ab7658-e7f2-43f9-b0de-5a12c8ff24a6/zenspath-entertainment-network Join us on Discord at bit.ly/zenspathdiscord (https://discord.com/invite/jsB8GURSvT) Where to find us: https://www.zenspath.com/podcast for the latest episodes, shorts, & more all in one place! Jeremy - Bluesky - https://bsky.app/profile/zenspath.com Instagram - https://www.instagram.com/zenspathcom/ Threads - https://www.threads.net/@zenspathcom Hive - @zenspath Discord - @zenspath Twitch - https://twitch.tv/zenspath YouTube - https://youtube.com/zenspathcom Stephen - Bluesky - https://bsky.app/profile/n1ntendo.bsky.social Hive - @swantendo Discord - @n1ntendo. (don't forget the "." at the end!) Chase - X - https://twitter.com/LegioXGaming Chris - He's around... Intro 00:00What We've Been Doing 57:05The Group Chat - Recent Pickups! 18:01The Group Chat - "RV There Yet" Travels 22:39Sony State of Play Japan - "Fatal Frame II Crimson Butterfly Remake" 29:39Sony State of Play Japan - "Dynasty Warriors Origins" DLC 30:13Sony State of Play Japan - "MotionRec" 31:14Sony State of Play Japan - "Tokyo Xtreme Racer" 31:58Sony State of Play Japan - PlayStation Gaming Monitor Announced 32:18Valve Announces Their "Steam Machine", "Steam Controller", & "Steam Frame" VR Headset 35:39"Pokopia" is a Key-Card & is Pokemon a First, Second, or Third Party Title? 1:11:26"Super Mario Galaxy Movie" Direct 1:33:43Previews & Players Panic Over a Talkative NPC in "Metroid Prime 4 Beyond" Demo & Trailer 1:38:53"Call of Duty Black Ops 7" Has Messed Up Single Player Requirements & Is Full of AI Slop 1:52:11"Hi-Fi Rush" Publishing Rights Have Transferred from Bethesda to Krafton 2:02:45Krafton Announces a "Voluntary Resignation Program" As They Replace Staff with AI 2:03:19The Speedrun 2:07:44The Big Question 2:12:43Outro & Where to Find Us 2:27:16
Nov. 7- 13: The highest rated E.R. ever, George Costanza loves bosco, Freddie Mercury's finale, 50 Cent tries movies, South Park sparks a hate crime against red heads, the Chilean miners get a film, Bryan Cranston is blacklisted, Diane Keaton just wants a perfect Christmas, and Bob and David are back…briefly. All that and more from 30, 20, and 10 years ago.
Bethesda Women's basketball To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices