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For the fifth consecutive year, the Departures Hall of Shannon Airport will be transformed to host the highly anticipated Explore Engineering Showcase 2026 on Thursday, 5th March. This inspiring event brings together 2,000 senior-cycle secondary school students, teachers, their parents, professionals, and industry leaders for a dynamic celebration of engineering excellence and innovation. Established in 2015, this annual event provides a unique platform for students and emerging engineers to speak directly with over 60 engineering companies in the Mid-West and gain insights into the latest technological advancements. Key educational institutions from across the Mid-West will come together to showcase the diverse pathways open to students, from apprenticeships and training bodies to third-level programmes, for students, parents, guidance counsellors, and teachers. Speaking today, Eimear Brophy, Chairperson of Explore Engineering, said: "The Explore Engineering Showcase is about inspiring future engineers and connecting them with real training and career opportunities close to home. We invite students, their parents, and educators to join us in Shannon Airport as we showcase the very best of what the Mid-West region has to offer the future of engineering talent." Commenting on the event, Ray O'Driscoll, Interim CEO of The Shannon Airport Group, said: "It's a real honour for us to host the Explore Engineering Showcase in Shannon Airport. Engineering and aviation go hand in hand, and several of the companies participating are an integral part of the Shannon Airport Business Park, where innovation and creativity thrive. It's wonderful to see the curiosity and passion for engineering this event helps to ignite in students – future talent who will undoubtedly play an important role in our business and the wider region in the years ahead." Attendees will have the opportunity to explore interactive exhibits, witness live demonstrations, and participate in hands-on activities designed to spark creativity and problem-solving skills. The Explore Engineering Showcase takes place in the Departures Hall of Shannon Airport on Thursday, 5th March 2026. Admission and parking are free. Pre-registration is not required. Doors open from 5 pm. For more details, please contact Fiona Murphy at Fiona.burke.murphy@outlook.com or visit www.explore-engineering.ie.
C-TRAN reports ridership surpassed 5 million trips in 2025, continuing a four-year growth trend driven by increases across most routes, expanded on-demand service, and strong performance from The Vine corridors. https://www.clarkcountytoday.com/news/c-tran-ridership-grows-for-fourth-consecutive-year/ #ClarkCounty #Transportation #PublicTransit #CTRAN #Ridership #BusService
2-9-26 Lobos still in control of At-Large bid despite a 2nd consecutive home loss
The Columbian recently reported that Clark County recorded the highest rate of evictions per capita in Washington state for the third year in a row. In 2025, Clark County landlords filed 2,275 cases to evict tenants, an increase of roughly 33% since 2023. Washington has passed legislation in recent years to help tenants, including a new law Governor Bob Ferguson signed last May that limits rent increases to no more than 10% in a year. In 2021, Washington became the first state in the nation to establish a right to free legal counsel for low-income tenants facing eviction. But amid growing need and rising caseloads, the Washington State Office of Legal Aid is seeking $3 million in supplemental funding from lawmakers for the next fiscal year. Mia Ryder-Marks is a reporter for The Columbian covering homelessness, affordable housing and veterans. She joins us for more details.
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Listen to the latest SBS Hindi news from India. 02/02/2026
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January 26, 2026 ~ Bud Denker, President of Penske Corporation discusses Team Penske's winning stream at Rolex 24 at Daytona. Hosted by Simplecast, an AdsWizz company. See https://pcm.adswizz.com for information about our collection and use of personal data for advertising.
Sumo: Tamawashi Gets Guinness Record Certificate for Consecutive Appearances
While some progress has been made in stabilizing the farm economy through the Farmer Bridge Assistance Program and Emergency Commodity Assistance Program, recent numbers show farmers still need help.
-Jake was on the scene (with Swim and friend David) in Evanston for what ended up being more of the same---2 nd half dominance, asthe Huskers outscored the Wildcats in the 2 nd half, 43-29…without much production from Rienk Mast or Jamarques Lawrence-Nebraska's defense was relentless again, and the offense hit 11/26 3-pointers..with Pryce Sandfort going for 22 points and BradenFrager again off the bench scoring 20 points…this team is really, really goodOur Sponsors:* Check out Aura.com: https://aura.com/remove* Check out BetterHelp: https://www.betterhelp.com* Check out Progressive: https://www.progressive.comAdvertising Inquiries: https://redcircle.com/brandsPrivacy & Opt-Out: https://redcircle.com/privacy
The Avalanche have lost consecutive games for the first time and their first regulation game at home this season, as they've hit a bit of a lull in the dog days of January. Is there anything to worry about long term from the loss to the Nashville Predators, or can they bounce back with a win over the Washington Capitals on Monday? Send questions to the mailbag here: https://forms.gle/7ytuJfsiTr1x3VDt6 Keep up with everything on the site at HockeyMountainHigh.com Follow the show: @HockeyMTNPod Follow Griffin: @GRYoungs Follow Christian: @Christian_Bolle Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Things are getting crazy in Nashville and the Preds are thinking playoffs all of a sudden! The Lightning might never lose another hockey game. And it's time for some teams to go all in for a cup this year: Avalanche, Stars, Bolts, Canes, and of course… the Oilers. The Professors of Puckline dish out electric weekend picks. The boys debate the value of the snooze button. And a game of Trivia Factorial takes us home NEW EPISODES EVERY TUESDAY & THURSDAY! Watch full episodes, shorts, and clips right here on YouTube. Listen to the podcast on Spotify or anywhere you get your pods. Subscribe & follow Empty Netters everywhere: YouTube: / @emptynetters Instagram: @EmptyNetters TikTok: @EmptyNetters X: @EmptyNetters PRESENTED by BetMGM. Download the BETMGM app and use code “NETTERS” and enjoy up to $1500 in bonus bets if you lose your first wager! Thanks to our Sponsors! BetMGM: Use bonus code NETTERS when signing up to receive up to $1500 in bonus bets if your first bet loses. Bauer: Get your hands on Bauer's newest innovation — the PULSE stick — and feel the difference. Get your hands on one at https://Bauer.comLUCY: Order your LUCY Today by going to https://www.lucy.co/Friday and use promo code FRIDAY for 20% off your first order Gambling problem? Call 1-800-GAMBLER (Available in the US) 877-8-HOPENY or text HOPENY (467369) (NY) 1-800-327-5050 (MA), 1-800-NEXT-STEP (AZ), 1-800-BETS-OFF (IA), 1-800-981-0023 (PR) 21+ only. Please Gamble Responsibly. See BetMGM.com for Terms. First Bet Offer for new customers only. Subject to eligibility requirements. Bonus bets are non-withdrawable. In partnership with Kansas Crossing Casino and Hotel. This promotional offer is not available in New York, Nevada, Ontario, or Puerto Rico. Learn more about your ad choices. Visit megaphone.fm/adchoices
"McElroy & Cubelic In The Morning" airs 7am-10am weekdays on WJOX-94.5!!See omnystudio.com/listener for privacy information.
Baseball hall of famer Cal Ripken Jr. joins David M. Rubenstein to discussed his legendary career and his work as a bestselling author, and gave viewers a tour of memorabilia from his decades in baseball. Learn more about your ad choices. Visit megaphone.fm/adchoices
Mike is at La Mission Mexican Restaurant! But before he talks over their menu, he talks about a man who took 6 consecutive flights to lock in his airline status, the top 25 Travel Cities, and the NEW Black Eyed Pea. This and more on Hour 2 of the Mike Boyle Restaurant Show!See omnystudio.com/listener for privacy information.
0:00 - The Avs lost back-to-back games in regulation, and we don't know how to handle it. It's been ages! Also, some good news: according to Shams Charania, Jokic is making great progress in his injury recovery, and he could be back later this month.Next Moseys categories: Worst Analogy, Let's Not Get HR Involved16:24 - Turns out, someone snatched the trademark for both "Las Vegas Athletics" and "Vegas Athletics"...which means the ACTUAL TEAM isn't allowed to use them.Next Moseys categories: Worst Prediction, Worst Question That May or May Not Be a Question31:04 - David Webb, the QB guru wunderkind, is being courted by lots of NFL teams right now. He could get hired as an OC or even a head coach! Both Webb and Vance Joseph might leave Denver and move up the NFL ladder.Next Moseys categories: Worst Treatment of Each Other, Huh??
On this week's episode of Out and About, Dr. Mae Gilliland of ArtsPartners of Central Illinois talks to Sharon Samuels Reed, founder and artistic director of The Heritage Ensemble. Sharon reflects on founding the Ensemble and the mission that continues to guide its work.
In this newscast, I report on the latest data on syphilis in Japan in 2025.
The Houston Texans are playoff bound for the third consecutive season! Marc Vandermeer and Andre Ware break down the thrilling 20-16 road victory over the Los Angeles Chargers at SoFi Stadium.See omnystudio.com/listener for privacy information.
In this episode Sam and Andrew first discuss some trades that happened right before the roster freeze with Marchment going to Columbus and Danault going to Montreal (3:15). Then they discuss an injury update with Jarvis being put on IR, Slavin's reduced minutes, and Nadeau being called up (8:09). For the last part of the episode they recap the brutal losses against Florida (15:42) and Tampa Bay (39:44). If you have any questions or just want to contact us please email us at: thecaniacreport@gmail.com Follow us on our Social Media Accounts below! X: https://twitter.com/TheCaniacReport Instagram: https://www.instagram.com/thecaniacreport/ BlueSky: https://bsky.app/profile/thecaniacreport.bsky.social Tiktok: https://www.tiktok.com/@thecaniacreportpod YouTube Link: https://www.youtube.com/@TheCaniacReport Donation Link: https://paypal.me/sgwallace917?country.x=US&locale.x=en_US Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
On Episode 755 of The Core Report, financial journalist Govindraj Ethiraj talks to Manas Majumdar Partner and Leader Oil & Gas, Fuels & Resources, PwC India.SHOW NOTES(01:00) Shares drift down the fourth consecutive session(02:45) Rising apprehension over Oracle's finances, a key player in the AI infra game(04:27) Sebi would like more women to invest in debt(05:06) 2026 is a busy year for Indian energy as more refineries go on stream, a demand outlook(15:45) India strengthens India's economic and geopolitical presence at the mouth of the Gulf with Oman FTA(18:13) Let that sink in: The Indian telecom industry saw overall overall subscriber base reaching 1.2 billion by NovemberRegister for India Energy Week 2026https://www.indiaenergyweek.com/forms/register-as-a-delegateFor more of our coverage check out thecore.inSubscribe to our NewsletterFollow us on:Twitter |Instagram |Facebook |Linkedin |Youtube
Hunter Cantwell grew up in Paducah, walked on at the University of Louisville under Coach Bobby Petrino, started a bowl game for UofL, and eventually made it to the NFL.He's been coaching the Christian Academy of Louisville Centurions for 6 years and has won the 3A state championship for the past four seasons.He has an amazing story to tell and much more direction to bring the young men who keep winning at sports and in life.
Golden State dropped consecutive clutch games over the weekend. Even with Steph Curry's heroic performances, the Warriors came up short. On "Dubs Talk," Bonta Hill and Monte Poole break down why leads keep slipping away from the Warriors late in games and how that has led to mediocrity in Golden State.(02:00) - Warriors drop consecutive clutch-time games to Timberwolves and Trail Blazers over the weekend(07:00) - Warriors' fourth-ranked defensive rating doesn't match the eye test(11:00) - How can Warriors' role players get a rhythm if their rotations keep changing?(17:00) - Joe Lacob won't be happy with Warriors' level of mediocrity(23:00) - Is Steve Kerr getting burnt out coaching this iteration of the Warriors?(26:30) - Warriors' blown leads in the fourth quarter are a problem(32:00) - Draymond Green and Jimmy Butler are starting to not fit together as well as we've seen Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Bobby and Mike remembered former Saints center Max Unger's outstanding career, and the guys criticized the flag-happy referees in the Saints' win over Carolina. They praised Saints rookie quarterback Tyler Shough for leading back-to-back game-winning drives. The guys also discussed the Saints' biggest needs in the 2026 NFL Draft.
Happy Friday and welcome back to another edition of "Under The Lights" as Cole and Dom return to talk through Aston Villa's 2-1 win over FC Basel in Switzerland and look ahead Sunday's trip away at West Ham United.You can listen for FREE on Acast, Apple Podcasts, and Spotify - dig in!WHAT DO WE DISCUSS?Another case of Unai Emery's men taking care of business; what did the lads make of the performance?What does Villa's 8th consecutive win mean to the team and supporters?Evann Guessand's role and development within the Villa squad.How important has squad depth been this season?What should we expect to see against West Ham on Sunday?STAY CONNECTED:Email: holtecast@gmail.comX: @HoltecastPodThreads: HoltecastBluesky: @holtecastpod.bsky.socialCole Pettem: @TalkAstonVillaDom Phillips: @_domphillipsEPISODE NOTES:Thank you to our charity partner, Acorns Children's Hopsice.Donate today to support a fantastic charity: https://www.acorns.org.uk/get-involved/donate/ Hosted on Acast. See acast.com/privacy for more information.
The WIP Midday Show react to the Eagles dropping their third game in a row and continuing to flounder. The Team is joined by Merrill Reese, Devan Kaney and Ross Tucker.
“If you get on cruise control and let everything start festering, it's gonna find a way to get out somehow…everybody makes mistakes, I made one and I apologized for it and moved on, and I'm better for it now.” Desmond Bane In one of the most authentic and real conversations we've had on The Pivot Podcast, Ryan Clark, Fred Taylor, and Channing Crowder sit with Orlando Magic star Desmond Bane — a player whose journey is as powerful as his jump shot and deep roots that have grounded him since day one. With humility at his core in all he does, Bane's talents have often been overshadowed by his quiet demeanor but this off season his value was at the forefront, when Orlando traded for the young star solidifying his place as one of the top players in the NBA. Bane opens up about the early adversity that fueled his rise, the overlooked beginnings that pushed him to grind harder than the next guy, and the deep bond he built with Ja Morant in Memphis — a brotherhood formed through shared battles, growth, and the pressures of leading a young franchise. Now, after a blockbuster trade to Orlando, Bane talks candidly about embracing a new chapter and the responsibility of being a cornerstone for a young Magic squad. He opens up on how it took a little while trying to find his place in a new arena and gives context to the uncharacteristic game ejection early on, and shares what one thing clicked that has fueled his explosive run, including his back-to-back 37-point performances that set the tone for what's becoming a breakout year in his new uniform and has his team 4-0 in the NBA Cup. Raised by his grandparents in the tight-knit community of Richmond, Indiana, Bane reflects on how small-town values, discipline, and love shaped the competitor and man he is today. It wasn't an easy path and the young star reveals his personal anxiety battles and how he redefined his path. He talks about the pain of loss and how his wife and kids helped him redefine purpose after grieving from so much change. And in a rare pivotal moment on the show, Desmond flips the conversation to Ryan, Channing and Fred, asking them how life is for them and how they have handled certain changes....truly a powerful part of the episode. Authentic, honest, and inspiring, this conversation captures Desmond Bane at a pivotal moment — reflecting on where he came from, honoring the people who raised him, and stepping boldly into the player he's proving he can be. Pivot Family, please like, comment and hit the subscribe button, we love hearing from you! Learn more about your ad choices. Visit megaphone.fm/adchoices
Marcus Jones joins WEEI Afternoons with Andy Hart and Nick “Fitzy” Stevens to talk about his electric punt-return touchdown, the Patriots improving to 11–2, and what he's looking forward to during the bye week. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices
Robbie Connor rushed for 96 yards and 3 touchdowns, Charlie Klass added 2 rushing touchdowns and Reid Hites threw for a touchdown as St. Ignatius took down Morgan Park 40-12 to win its second straight Prep Bowl.Become a supporter of this podcast: https://www.spreaker.com/podcast/friday-night-drive--3534096/support.
Robbie Connor rushed for 96 yards and 3 touchdowns, Charlie Klass added 2 rushing touchdowns and Reid Hites threw for a touchdown as St. Ignatius took down Morgan Park 40-12 to win its second straight Prep Bowl.Become a supporter of this podcast: https://www.spreaker.com/podcast/friday-night-drive--3534096/support.
The full review from IKON Park with Laura Spurway, Meg McDonald and Sarah Burt. See omnystudio.com/listener for privacy information.
Recap of the game.
Beat reporter Coty Davis and Detroit News contributor Tarohn Finley talk about the Pistons' 11-game winning streak heading into Saturday's game against the Bucks in Milwaukee. This year's team coached by J.B. Bickerstaff is off to their best start (13-2) in 20 years and sit just a couple wins shy of the franchise record for consecutive wins. Larry Brown’s “Goin’ to Work” team won 13 in a row in 2003-2004, while Chuck Daly’s “Bad Boys” had streaks of 12 and 13 wins in 1989-1990.
The New York Jets have won their second straight game despite trading two of their key players in the last week and another underwhelming performance by Justin Fields. However, the Jets found a way to win. Why this is a big win for this regime, what they need to do on Thursday Night, and what to look forward to over the final eight games. Want more Jets content? make sure to subscribe!
PLUS - Man City v Liverpool & Playing 417 CONSECUTIVE matches!! A look back at the week of sport, and a look ahead of this weekend's action, with Andy & Gary - THE SPORTCAST (Ep 192) 00:00 - Intro 03:30 - Battle of The Sexes 15:00 - Mary Earps Book 25:00 - Are Liverpool Back? 38:30 - Man City v Liverpool 43:00 - Everton v Fulham 49:00 - Gana Gueye 53:00 - Are Everton Fans Having Moyes? 01:03:00 - Phil Neal's Outrageous Record Join us on Patreon for our Betting Show, Bonus Episodes and all of the other Patreon Perks... https://www.patreon.com/legitpodcast Shout out to our sponsors... The Feathers - Bootle | https://www.instagram.com/the.feathersbootle/ Hill Dickinson | https://www.hilldickinson.com/ Comoletics | Get 30% off with code "LEGIT30" at checkout https://comoletics.com/ For BOXPARK tickets & access to COMOLETICS huge giveaway: https://boxpark.co.uk/events/propel-xmas-pop-up-market/ #Liverpool #LFC #Everton #EFC #Sport #Podcast #PremierLeague #Podcast #Sports #Football #News
At the 2025 World Championships in Tokyo Japan, Mondo Duplantis, Faith Kipyegon, and Ryan Crouser all won gold medals in their respective events, which gave them an unprecedented 5 consecutive gold medals at 5 consecutive global championships, in 5 consecutive years.Let's breakdown how each of them won their gold medals and a bit of history of consecutive medalists at previous global championships.--------------------------------------------Chapters:00:00 Intro00:40 History of Olympic/World Championship Cycle02:28 Five consecutive Global Champs04:12 Athletes with 3 consecutive medals04:52 Athletes with more than 3 consecutive medals05:38 Athletes with 3 consecutive gold medals06:06 Athletes with more than 3 consecutive gold medals06:38 2021-2025 Championships06:53 Contenders for 5 golds after 202207:24 What happened at Budapest 202308:23 What happened at Paris 202408:51 What happened at Tokyo 202509:10 How Mondo Duplants won 5 Golds10:11 How Faith Kipyegon won 5 Golds11:41 How Ryan Crouser won 5 Golds14:26 5 consecutive medals of any color15:11 2026 World Ultimate Championships16:03 Summary--------------------------------------------
In a new episode of The Bernie Fratto Show, Bernie Fratto opens the show reacting to the Dodgers back-to-back World Series victory. Professional Sports Handicapper Bill Krackomberger joins the show to some of the lines surrounding Game 7 of the World Series and some of the lines heading into Week 9 of the NFL! NBA Inside Mark Medina joins the show to respond to some of the rumors surrounding LeBron James and the reasons he’s been MIA around the Lakers, Mavericks C Anthony Davis’s injury impact, if the Chicago Bulls look legit & more! Bernie then dives more into how baseball is the most difficult sport to repeat, and gives a full recap of all the great storylines from a busy day in College Football. Ohio State Insider Don Gesick joins the show to talk about Ohio State’s dominant win over Penn State, rumors regarding their OC being considered for HC opportunities + a new edition of Fantasy Files, & your calls during the Midnight Hour! See omnystudio.com/listener for privacy information.
Support the show: Antiwar.com/donatePhone bank for Defend the Guard: https://defendtheguard.us/phonebankSign up for our newsletter: https://www.antiwar.com/newsletter/
Charlotte is joined by Ordy and Kyle to discuss Newcastle's FOURTH League Cup QF in as many years under Eddie Howe. They discuss: easy win against a good Spurs side with 8 changes Ramsdale, Tonali and a bit of Barnes next round - how bothered are we? Join us on Patreon! https://www.patreon.com/tfpodcast Learn more about your ad choices. Visit podcastchoices.com/adchoices
In this episode of JCO PO Article Insights, host Dr. Jiasen He summarizes the article, "Somatic Mutation Profiles of Colorectal Cancer by Birth Cohort" by Gilad, et al published October 11, 2025. TRANSCRIPT Jiasen He: Hello, and welcome to the JCO Precision Oncology Article Insights. I am your host, Jiasen He, and today, we will be discussing the JCO Precision Oncology article, "Somatic Mutation Profiles of Colorectal Cancer by Birth Cohort," by Dr. Gilad and colleagues. Early-onset colorectal cancer is defined as colorectal cancer diagnosed before the age of 50. Several reports have suggested that early-onset colorectal cancer has unique characteristics. Compared with late-onset colorectal cancer, early-onset colorectal cancer cases are more commonly found in the distal colon or rectum, tend to be diagnosed at more advanced stages, and may display unfavorable histologic features. Although the overall incidence of colorectal cancer has declined in recent decades, the incidence of early-onset colorectal cancer continues to rise. This increase appears to be driven by birth cohort effects. The reasons behind this rise remain unclear but are likely multifactorial, involving changes in demographics, diet, lifestyle, environmental exposures, and genetic predisposition. At the same time, studies have shown conflicting results regarding whether there are differences in the mutation profiles between early-onset and late-onset colorectal cancer. Therefore, it is crucial to explore whether colorectal cancer somatic mutational landscape differs across birth cohorts, as this could provide important insight into generational shifts in colorectal cancer incidence. To address this question, the authors conducted a retrospective study to characterize the mutation spectrum of colorectal cancer across different birth cohorts. Consecutive colorectal cancer patients who underwent somatic next-generation sequencing at the University of Chicago pathology laboratory between 2015 and 2022 were retrospectively identified. Tumors were tested for 154 to 168 genes and categorized as either microsatellite stable or high according to established thresholds. Patients with hereditary cancer syndromes or inflammatory bowel disease were excluded. Participants were then grouped into birth cohorts by decades, as well as into two major groups: those born before 1960 and after 1960. Genes that were identified in at least 5% of the sample were selected and grouped into 10 canonical cancer signaling pathways. These genes and pathways were then included in the analysis to explore their association with colorectal cancer across different birth cohorts and age groups. A total of 369 patients were included in the study, with a median birth year of 1955 and a median age at colorectal cancer diagnosis of 62.9 years. 5.4% were identified as having microsatellite-high tumors. The median tumor mutational burden was 5 mutations per megabase for microsatellite-stable tumors and 57.7 mutations per megabase for microsatellite-high tumors. Patients with microsatellite-high tumors tended to have earlier birth years and were diagnosed at an older age. However, after adjusting for potential confounders, neither birth year nor age remained statistically significant. Similarly, after controlling for confounders, no significant associations were observed between birth year or age and mutation burden. In this cohort, APC, TP53, and KRAS were the most frequently mutated genes. No statistically significant differences in the prevalence of gene mutations were observed across birth cohorts. Correspondingly, the most affected signaling pathways were the Wnt, TP53, and (RTK)/RAS pathways. Similar to the gene-level finding, no significant differences in the prevalence of these pathways were identified among birth cohorts. When examining patients born before and after 1960, the authors found that the older birth cohorts were diagnosed at an older age and had higher tumor mutational burden. However, no significant differences were observed in any of the genes or pathways analyzed. Among microsatellite-stable tumors, 18.3% were classified as early-onset colorectal cancer, while 81.1% were late-onset colorectal cancer. Consistent with previous reports, early-onset colorectal cancers in this cohort were more likely to be left-sided and more common among more recent birth cohorts. However, no significant differences were identified in any of the examined genes or pathways when comparing early-onset to late-onset colorectal cancer. In this cohort, a higher prevalence of early-onset colorectal cancer was observed among more recent birth cohorts, consistent with previous reports. Still, no distinct mutational signature was identified between the early and late birth cohorts. The authors proposed that the lack of distinct mutational profile by age or birth cohort may be due to the limited number of key molecular pathways driving colorectal cancer. Although environmental exposures likely differ across generations, the downstream effects may have converged on similar biological mechanisms, leading to comparable somatic mutations across cohorts. Alternately, they proposed that the observed birth cohort differences in colorectal incidence may be driven by distinct mutation signatures, epigenetic alterations, or changes in the immune microenvironment rather than variations in canonical gene mutations. As the authors noted, given the retrospective nature of this study, its modest sample size, and the predominance of advanced-stage tumors, larger prospective studies are needed to validate these findings. In summary, this study found no significant differences in the mutational landscape of colorectal cancer across birth cohorts or age groups. The authors proposed that the generational shift in colorectal cancer incidence is unlikely to be driven by changes in the underlying tumor genomics. However, larger prospective studies are needed to validate these findings. Thank you for tuning in to JCO Precision Oncology Article Insights. Do not forget to subscribe and join us next time as we explore more groundbreaking research shaping the future of oncology. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.
The Daily Drama Podcast with Steve Burton & Bradford Anderson
We discuss the night that was EMMY NIGHT. How did Steve feel about his spray tan? How did Steve almost miss Jonathan's speech? What happens when your show wins the big award?? A fun discussion of Daytime's Biggest Night! Watch This Episode on YouTube: https://youtu.be/OIyBVWzJqOE For Tickets to Our Live Holiday Shows Go To: https://www.stonecoldandthejackal.com/tour Follow us on Facebook at: https://www.facebook.com/StoneColdandTheJackal/ Follow un on Instagram at https://www.instagram.com/stonecoldandthejackal/ Get even more on PATREON: https://www.patreon.com/stonecoldandthejackal
Your EXCLUSIVE NORD VPN discounted offer is here → https://nordvpn.com/toon There's no risk with NORD's 30-day money back GUARANTEE! One subscription can be used across 10 devices! Stay secure while online. --- Andrew is joined by Sammy James from Fulhamish - a podcast covering this weekend's opponents, Fulham. Newcastle will be looking to get their second win of the week after beating Benfica in the Champions League. Sammy admits, Nick Woltemade is the man who scares him. Learn more about your ad choices. Visit podcastchoices.com/adchoices
This inspiring conversation with Denise dives into her extraordinary 40+ year career in the travel industry, her rebirth into health and wellness, and her daily commitment to walking 10 miles—over 1,172 consecutive days. From surviving trauma to creating three thriving businesses, Denise shares her journey of resilience, self-belief, and intentional living. Her story beautifully weaves together entrepreneurship, personal health, and a mindset of awe.Major Takeaways / Learnings:Believe in yourself first. Denise built her career from hardship by cultivating a positive mindset and surrounding herself with mentors.Look in the mirror. A daily ritual of affirmations (“I love you. You are strong. You are worthy.”) became a cornerstone of her confidence.Health is wealth. Her transformation began with honest self-assessment, journaling eating habits, drinking more water, prioritizing rest, and adding movement back into her life.Start small, stay consistent. What began as short walks turned into over 1,000 consecutive days of 10-mile walks.Excuses are non-negotiable. Rain or shine, she shows up for herself.Travel + wellness = awe. She helps clients create experiences that light them up from the inside—not just trips for social media.Overcome trauma through connection. Faith, therapy, nature, and community helped her rebuild and thrive.Memorable Quotes:“Your health is your wealth. Don't wait until it's too late to pour into yourself.”“I was looking in the mirror, but I wasn't seeing myself.”“Movement is key to life, to the brain, to how you think and feel.”“Walking is non-negotiable. Excuses are non-negotiable.”“Some climb the mountain to see the world; others climb it to be seen by the world.” Why It Matters / How to Use It:Denise's story is a masterclass in intentional living: starting small, anchoring in personal rituals, and committing to yourself daily. Entrepreneurs, leaders, and anyone feeling stuck can use her example to reset their habits—focusing on health, gratitude, and purpose. It's a reminder that awe isn't found on a screen; it's found in how you live each day.Connect with Denise:Instagram: thehealthy_travelerEmail: TripPro@verizon.netSpecial note: Denise embodies the spirit of “Most People Don't… But YOU Do.” She doesn't just talk about mindset and movement—she lives it.
This week we welcome on former Maryland linebacker Tre Watson Sr.. The former player discusses why the Terps have lost three straight games after having the lead in fourth quarter. We also get his perspective on if Mike Locksley is still the man for the head coaching job at Maryland. As always we talk this week in Maryland Athletics.
Batavia totaled over 400 yards of offense as it downed St. Charles East 31-13 to clinch its 14th straight playoff appearance on Friday.Become a supporter of this podcast: https://www.spreaker.com/podcast/friday-night-drive--3534096/support.
Sponsored by thegalindocollective.com, BHIhats.com, Austin.Patchmaster.com - A Homecoming fiasco, Texas State (3-3, 0-2) squandered a 28-7 first half lead to lose to the Troy Trojans (4-2, 2-0) in overtime. Consecutive losses despite the offense gaining over 500 yards and scoring at least 30 points - it's time for GJ Kinne and the Texas State Bobcats to take accountabilty for the underperforming defense. Keff Ciardello is here to talk all about it.
Tim May joined Baskin and Phelps to preview the Buckeyes' upcoming match up with Illinois and what challenges he expects Ohio State to face. He also went around the Big 10 to break down the different match ups and discussed whether or not he thinks any of them can challenge Ohio State down the stretch.
Today we talk to one of the most influential Athletes in the Master's Division. Not only has he won the CrossFit Games 6 Consecutive times he has also built the divisions biggest training camp and programmer. They are one of the biggest sponsors, influencers and businesses in the space. How does Jason do it all, we find out today...
Mysterious James and I emerge from our three-night Cannon Beach odyssey to accidentally unlock our cycling superpowers, turning a modest Tillamook target into a shocking 52-mile triumph. It's the usual stuff: ice cream as performance enhancer, and the stunning revelation that hydration might actually matter. But with tomorrow's weather turning and our schedule still behind, will this newfound confidence carry us forward or set us up for an epic crash? Key Highlights Morning departure from Cannon Beach with sunny weather (rain expected tomorrow) Arch Cape Tunnel challenge - one of the less enjoyable parts of the Oregon coast, but navigated successfully with proper lighting and safety gear Strong riding performance despite variable winds - tailwinds providing good speed, headwinds creating challenges around rivers and inlets Confidence boost as both riders felt strong throughout the day, a marked improvement from their struggles the previous day leaving Beaverton Hydration success - Tim credits focused hydration efforts for dramatically improved performance Cape Lookout State Park arrival - described as potentially "the best camp on the coast" with individual pod-like clearings and ocean wave sounds Route Details Departed Cannon Beach early morning Climbed through Arch Cape Tunnel to Manzanita (20-mile checkpoint) Continued south past Garibaldi and Bay City to Tillamook Extended ride from Tillamook to Cape Lookout State Park Riders met at Safeway in Tillamook for resupply (chicken strips and ice cream) Camp Review: Cape Lookout State Park Pros: - Excellent location directly on the coast - Individual pod-like campsites with perfect flat ground - Beautiful ocean wave sounds - Great overall facilities Cons: - Long walk to bathhouse/showers - Charging stations only have USB-A ports (no USB-C or standard 110V outlets) Tomorrow's Plan Targeting Beverly Beach as the main goal South Beach as potential stretch goal (though 70 miles seems too ambitious) Weather forecast: overcast and cool - ideal "James and Tim weather" Still working out end-of-week logistics due to being behind schedule Technology MVP Perplexity AI proving invaluable for route planning and logistics, including confirming their direct route choice over the longer ACA (Adventure Cycling Association) scenic route. Statistics Miles Biked: 52 Times Tim arrived before James: 2 (hmm… that's not normal. Foreshadowing…) Power of James's insane phone charger: 100 watts Consecutive nights at Cannon Beach: 3 (do I need to declare it as a part time residence this year?) • • Flats: Zero