Podcasts about Sigmoid

Ever wondered how to stop LLMs from hallucinating or making things up? The answer is RAG (Retrieval-Augmented Generation), and it's a critical technique for building reliable, fact-based AI applications.In this episode, Alan sits down with Abhinav Kimothi, Director of Data Science at Sigmoid and author of the Manning book, "A Simple Guide to RAG". Abhinav demystifies this powerful concept, making it accessible for developers and enthusiasts at any level.This is a must-listen for anyone looking to move beyond basic chatbot functionality and build truly intelligent, trustworthy AI.

Welcome to the Sterile Technique Podcast! It's the podcast about Surgical Technology. Whether you are a CST or CSFA, this podcast helps you earn CE credits and improve your surgery skills in the OR. This episode discusses an article in the October 2016 issue of The Surgical Technologist, the official journal of the Association of Surgical Technologists (AST). The article is titled, "Robotic Sigmoid Colectomy with NOSE". "Scrub in" at steriletpodcast.com and on Twitter, @SterileTPodcast (twitter.com/SterileTPodcast). This podcast is a Dybas Media production. Sound effects adapted from GarageBand and sindhu.tms at https://freesound.org/people/sindhu.tms/sounds/169065/ and licensed courtesy of https://creativecommons.org/licenses/by-nc/3.0/.

In this episode of The Greenbook Podcast, host Lenny Murphy sits down with Deb, Director of Data Science at Sigmoid Analytics and a 2025 Greenbook Future List Honoree. Deb shares insights into solving complex data challenges, the evolving role of Gen AI in analytics, and how companies are integrating AI-driven efficiencies. They discuss the future of data science, the shift towards strategic problem-solving, and the importance of upskilling talent in an AI-powered world. Tune in for a thought-provoking discussion on how organizations are embracing AI while navigating unknowns in the industry.Key Takeaways:AI is revolutionizing data analytics, but strategic thinking and human expertise remain essential.Organizations must embrace unknowns and invest in future-proof AI strategies.The industry is shifting from traditional statistical models to AI-driven insights with LLMs and automation.The future of analytics will prioritize business impact over technical complexity.Developing strong problem-solving skills is critical for the next generation of data scientists.Resources & Links:Learn more about Sigmoid AnalyticsYou can reach out to Debapriya Das on LinkedIn.Many thanks to Debapriya Das for being our guest. Thanks also to our production team and our editor at Big Bad Audio.

Sepp Hochreiter, the inventor of LSTM (Long Short-Term Memory) networks – a foundational technology in AI. Sepp discusses his journey, the origins of LSTM, and why he believes his latest work, XLSTM, could be the next big thing in AI, particularly for applications like robotics and industrial simulation. He also shares his controversial perspective on Large Language Models (LLMs) and why reasoning is a critical missing piece in current AI systems.SPONSOR MESSAGES:***CentML offers competitive pricing for GenAI model deployment, with flexible options to suit a wide range of models, from small to large-scale deployments. Check out their super fast DeepSeek R1 hosting!https://centml.ai/pricing/Tufa AI Labs is a brand new research lab in Zurich started by Benjamin Crouzier focussed on o-series style reasoning and AGI. They are hiring a Chief Engineer and ML engineers. Events in Zurich.Goto https://tufalabs.ai/***TRANSCRIPT AND BACKGROUND READING:https://www.dropbox.com/scl/fi/n1vzm79t3uuss8xyinxzo/SEPPH.pdf?rlkey=fp7gwaopjk17uyvgjxekxrh5v&dl=0Prof. Sepp Hochreiterhttps://www.nx-ai.com/https://x.com/hochreitersepphttps://scholar.google.at/citations?user=tvUH3WMAAAAJ&hl=enTOC:1. LLM Evolution and Reasoning Capabilities[00:00:00] 1.1 LLM Capabilities and Limitations Debate[00:03:16] 1.2 Program Generation and Reasoning in AI Systems[00:06:30] 1.3 Human vs AI Reasoning Comparison[00:09:59] 1.4 New Research Initiatives and Hybrid Approaches2. LSTM Technical Architecture[00:13:18] 2.1 LSTM Development History and Technical Background[00:20:38] 2.2 LSTM vs RNN Architecture and Computational Complexity[00:25:10] 2.3 xLSTM Architecture and Flash Attention Comparison[00:30:51] 2.4 Evolution of Gating Mechanisms from Sigmoid to Exponential3. Industrial Applications and Neuro-Symbolic AI[00:40:35] 3.1 Industrial Applications and Fixed Memory Advantages[00:42:31] 3.2 Neuro-Symbolic Integration and Pi AI Project[00:46:00] 3.3 Integration of Symbolic and Neural AI Approaches[00:51:29] 3.4 Evolution of AI Paradigms and System Thinking[00:54:55] 3.5 AI Reasoning and Human Intelligence Comparison[00:58:12] 3.6 NXAI Company and Industrial AI ApplicationsREFS:[00:00:15] Seminal LSTM paper establishing Hochreiter's expertise (Hochreiter & Schmidhuber)https://direct.mit.edu/neco/article-abstract/9/8/1735/6109/Long-Short-Term-Memory[00:04:20] Kolmogorov complexity and program composition limitations (Kolmogorov)https://link.springer.com/article/10.1007/BF02478259[00:07:10] Limitations of LLM mathematical reasoning and symbolic integration (Various Authors)https://www.arxiv.org/pdf/2502.03671[00:09:05] AlphaGo's Move 37 demonstrating creative AI (Google DeepMind)https://deepmind.google/research/breakthroughs/alphago/[00:10:15] New AI research lab in Zurich for fundamental LLM research (Benjamin Crouzier)https://tufalabs.ai[00:19:40] Introduction of xLSTM with exponential gating (Beck, Hochreiter, et al.)https://arxiv.org/abs/2405.04517[00:22:55] FlashAttention: fast & memory-efficient attention (Tri Dao et al.)https://arxiv.org/abs/2205.14135[00:31:00] Historical use of sigmoid/tanh activation in 1990s (James A. McCaffrey)https://visualstudiomagazine.com/articles/2015/06/01/alternative-activation-functions.aspx[00:36:10] Mamba 2 state space model architecture (Albert Gu et al.)https://arxiv.org/abs/2312.00752[00:46:00] Austria's Pi AI project integrating symbolic & neural AI (Hochreiter et al.)https://www.jku.at/en/institute-of-machine-learning/research/projects/[00:48:10] Neuro-symbolic integration challenges in language models (Diego Calanzone et al.)https://openreview.net/forum?id=7PGluppo4k[00:49:30] JKU Linz's historical and neuro-symbolic research (Sepp Hochreiter)https://www.jku.at/en/news-events/news/detail/news/bilaterale-ki-projekt-unter-leitung-der-jku-erhaelt-fwf-cluster-of-excellence/YT: https://www.youtube.com/watch?v=8u2pW2zZLCs

Welcome to the latest installment of "The Interventional Endoscopist," where we delve into the practical application of the Endorotor device, a novel innovation transforming the landscape of tissue resection. In this episode, I share my personal experiences with Endorotor, discussing its integration into my practice and its current applications. Whether you're an established professional seeking to stay informed on the latest advancements, or a curious individual eager to gain insight into the future of medicine, this podcast offers a wealth of information. Join us as we uncover the intricacies of the Endorotor device, its role in modern healthcare, and its potential for shaping the medical practices of tomorrow.       Important Links:  Academic Links: Hollerbach S, Wellmann A, Meier P, Ryan J, Franco R, Koehler P. The EndoRotor(®): endoscopic mucosal resection system for non-thermal and rapid removal of esophageal, gastric, and colonic lesions: initial experience in live animals. Endosc Int Open. 2016 Apr;4(4):E475-9. doi: 10.1055/s-0042-105207. Epub 2016 Mar 30. PMID: 27092332; PMCID: PMC4831928. Surkunalingam N, Das A, Khosravi F, Sachdev M. Sigmoid colon polyp EMR with novel endoscopic morcellator. VideoGIE. 2018 May 29;3(6):191-192. doi: 10.1016/j.vgie.2018.04.006. PMID: 30128384; PMCID: PMC6098755. Vyas N, Sachdev M, Das A, Khosravi F. Pancreatic necrosectomy using an automated mechanical endoscopic tissue extraction device. VideoGIE. 2018 Sep 25;3(11):354-355. doi: 10.1016/j.vgie.2018.08.005. PMID: 30402583; PMCID: PMC6206328. Rizzatti G, Rimbas M, Impagnatiello M, Gasbarrini A, Costamagna G, Larghi A. Endorotor-Based Endoscopic Necrosectomy as a Rescue or Primary Treatment of Complicated Walled-off Pancreatic Necrosis. A Case Series. J Gastrointestin Liver Dis. 2020 Oct 27;29(4):681-684. doi: 10.15403/jgld-2534. PMID: 33118541. Bazarbashi AN, Ge PS, de Moura DTH, Thompson CC. A novel endoscopic morcellator device to facilitate direct necrosectomy of solid walled-off necrosis. Endoscopy. 2019 Dec;51(12):E396-E397. doi: 10.1055/a-0956-6605. Epub 2019 Jul 24. PMID: 31340385. Other Links https://www.interscopemed.com/ https://mtendoscopy.com/products/gastroenterology/resection-retrieval/emr-esd/endorotor-epr/  

In this episode I am discussing about epidemiology, etiopathogenesis, clinical features, diagnostic investigations, complications and treatment of Sigmoid Volvulus.

Divertiküler hastalıklar, tıbbi uygulamada sıkça karşılaşılan ve zaman zaman karmaşık yaklaşımlar gerektiren durumlar arasında yer alır. Özellikle acil serviste bu hastalığın doğru teşhis ve tedavisi, hızlı ve etkili bir müdahale gerektirir. Bu yazıda, divertiküler hastalıkların temel kavramlarına, sıklıkla karşılaşılan türlerine ve acil serviste bu hastalıklara nasıl yaklaşılması gerektiğine dair bilgilere yer verilmektedir. Tanımlar Gerçek divertikül, kas tabakasını da içeren bağırsak duvarının tüm katmanlarını etkilerken, psödodivertikül yalnızca mukoza ve submukoza tabakası ile kaplanır. Psödodivertikül, kas tabakasının zayıf noktalarından çıkıntı yapar ve büyük olasılıkla daha önce delinmiş bağırsak damarlarından kaynaklanmaktadır. Divertiküler hastalık, geniş bir klinik spektrumu kapsayan ve acil servislerde sıkça karşılaşılan bir gastrointestinal sorundur. Divertikülozis: Divertikülozis, kolonun zayıf bölgelerinde divertikül adı verilen küçük keseciklerin oluşumu ile karakterizedir. Bu kesecikler genellikle sigmoid kolon bölgesinde yer alır ve genelde belirti vermeyen bir durumdur. Divertikülozisin prevalansı yaşla birlikte artar ve Batı ülkelerinde yaygındır. Divertikülit: Divertikülit, bu divertiküllerin iltihaplanması ve enfekte olması durumudur. Hastalar genellikle sol alt karın ağrısı, ateş, bulantı, kusma ve değişen dışkılama alışkanlıkları gibi semptomlar ile başvurur. Etiyoloji​1​ Esas olarak yaşam tarzı ve çevresel faktörlerden kaynaklanır Diyet: Düşük lifli, yağ ve kırmızı etten zengin diyetler divertikülit riskini artırabilir. Obezite Düşük fiziksel aktivite Artan yaş Sigara içmek Diğer nedenler: genetik faktörler Bağ dokusu bozuklukları (örn. Marfan sendromu, Ehler-Danlos sendromu) Otozomal dominant polikistik böbrek hastalığı Klinik DivertikülozisGenellikle asemptomatikÖzellikle kronik kabızlıkla ilişkiliyse karın ağrısıyla kendini gösterebilir. Divertiküler kanama DivertikülitÇoğunlukla subfebril ateşSigmoid kolon en sık etkilenen bölgedir → sol alt kadran ağrısı şikayeti sıktırMuhtemelen hassas, ele gelen kitle (perikolonik inflamasyon )Bağırsak alışkanlıklarında değişiklikler gözlemlenebilir (vakaların yaklaşık %50'sinde kabızlık ve vakaların %25-35'inde ishal )İdrar aciliyeti ve sıklığında artış gözlenebilir (vakaların yaklaşık %15'inde ) Akut karın : olası perforasyon ve peritoniti gösterir Nadiren: hematokezya gözlemlenebilir Divertikül ve Divertikülit Patofizyolojisi: Divertiküller, en yaygın olarak sigmoid kolon duvarının zayıflaması ve intraluminal basıncın artmasıyla bağırsak duvarının yaşa bağlı veya fizyolojik zayıflığının bir kombinasyonu sonucu oluşurlar. Divertikülit, bir divertikülün tıkanması ve bakteriyel overgrowth ile ilişkilidir. Bu durum, divertikülde iltihaplanmaya ve sonrasında perforasyon, abses oluşumu, fistülizasyon ve peritonit gibi komplikasyonlara neden olabilir. Divertikül Oluşumu: Zayıf Bağırsak Duvarı: Divertiküller, genellikle bağırsak duvarındaki zayıflık nedeniyle oluşur. Bu zayıflık, bağırsak kası zayıflığı ve bağ dokusu eksikliği nedeniyle olabilir. Artmış Intraluminal Basınç: Dışkılama sırasında artan intraluminal basınç, bu zayıf alanlarda bağırsak duvarının dışarı doğru itilmesine neden olabilir, bu da divertiküllerin oluşumuna neden olur. Konumu: Divertiküller genellikle kolonun sigmoid bölgesinde oluşur, çünkü bu bölge genellikle en yüksek intraluminal basınca sahiptir. Divertikülitin Gelişimi: Fekal Retansiyon: Divertiküllerde dışkı retansiyonu, bakteri sayısında artışa ve divertiküllerin iltihaplanmasına neden olabilir. Bakteriyel Overgrowth: Divertiküllerdeki fekal materyal, bakteriyel aşırı büyümeye (overgrowth) zemin hazırlar. Bu bakteriler, divertikül duvarını tahriş eder ve iltihaplanmayı tetikler. İltihaplanma: Bakteriyel enfeksiyon ve tahriş, divertikülün iltihaplanmasına neden olur. Bu, divertikülitin tipik semptomları olan ağrı,

In this episode, we introduce the Sigmoid Curve and practical ways you can drive sustained success on your team.

Interview with Ville Sallinen, MD, PhD, and Alexandre Santos, MD, authors of Quality-of-Life and Recurrence Outcomes Following Laparoscopic Elective Sigmoid Resection vs Conservative Treatment Following Diverticulitis: Prespecified 2-Year Analysis of the LASER Randomized Clinical Trial. Hosted by Amalia Cochran, MD. Related Content: Quality-of-Life and Recurrence Outcomes Following Laparoscopic Elective Sigmoid Resection vs Conservative Treatment Following Diverticulitis

Interview with Ville Sallinen, MD, PhD, and Alexandre Santos, MD, authors of Quality-of-Life and Recurrence Outcomes Following Laparoscopic Elective Sigmoid Resection vs Conservative Treatment Following Diverticulitis: Prespecified 2-Year Analysis of the LASER Randomized Clinical Trial. Hosted by Amalia Cochran, MD. Related Content: Quality-of-Life and Recurrence Outcomes Following Laparoscopic Elective Sigmoid Resection vs Conservative Treatment Following Diverticulitis

What does a mathematical concept from the business world have to do with Finishing Well? Hal and Randy discuss a commonly understood theme in business, life, etc and how a person in their senior years can approach this cycle of life. Visit finishingwellministries.org/podcast for more episodes from Finishing Well Ministries!Email us: Hal@finishingwellministries.orgFollow us on Facebook: https://www.facebook.com/finishingwellministriesSupport Our Ministry: https://www.finishingwellministries.org/donateAre there biblical principles to help us understand how to finish well?Join Dr. Habecker LIVE on ZOOM for a greater understanding of the SEVEN Essentials to Finishing Life Well: https://www.finishingwellministries.org/upcoming-eventsThanks for listening as we all strive to live and finish life well!

Sigmoid volvulus

By fiscal year 2026, at least 12 percent of the free-on-board value of Apple's global iPhone shipments could be made in India, Inc42 reports, citing a report by Business Standard that is behind a paywall. Byju's, India's most-valued startup, yesterday, reported losses of Rs. 4,589 crore for the fiscal year that ended March 31, 2021, which is close to a 20-fold increase over the Rs. 231.69 crore adjusted loss for the previous fiscal year, Moneycontrol reports. And SoftBank Group could be planning another Vision Fund, Wall Street Journal reports. Notes: Byju's, India's most-valued startup, yesterday, reported losses of Rs. 4,589 crore for the fiscal year that ended March 31, 2021, which is close to a 20-fold increase over the Rs. 231.69 crore losses for the previous fiscal year, Moneycontrol reports. The company's revenue for FY21 fell 3 percent year on year to Rs. 2,428 crore on a consolidated basis, down from Rs. 2,511 crore the previous year, according to Moneycontrol. By the fiscal year 2026, at least 12 percent of the free-on-board value of Apple's global iPhone shipments could be made in India, Inc42 reports, citing a report by Business Standard on Sep. 12 that is behind a paywall. Apple has been stepping up efforts to boost production in India to reduce its dependence on China, where currently almost all its iPhones are made. According to numbers submitted to the government by Foxconn, Wistron and Pegatron, India might account for at least 12 percent of the free-on-board value of Apple iPhones manufactured by its vendors worldwide. Free-on-board value typically refers to the cost of the goods being shipped including transportation to specific destinations, insurance, loading and unloading and so on. The total value of iPhones sold worldwide could reach $250 billion in FY26 and the total free-on-board of iPhones made in India would be around 12 percent of that, according to the Business Standard repot, as cited by Inc42. SoftBank Group, one of the world's biggest investors in tech startups, is considering the launch of a new giant fund even though its first and second Vision Funds have been hit with big losses owing to the global tech route, Wall Street Journal reports. The Tokyo-based tech conglomerate, by far the world's largest startup investor in recent years, would likely use its own cash for what would be the third SoftBank Vision Fund if it moves ahead with the plan, according to the Journal. Sigmoid, a data engineering, analytics and AI solutions company in Silicon Valley, has closed $12 million in Series B funding, in a mix of primary and secondary investments from Sequoia Capital India. Founded in 2013 by IIT alumni Lokesh Anand, Mayur Rustagi and Rahul Kumar Singh, Sigmoid has a team of about 500 data professionals, who offer deep expertise in data engineering, cloud data modernization, artificial intelligence, and DataOps, according to the release. Theme music courtesy Free Music & Sounds: https://soundcloud.com/freemusicandsounds

Bu yazımda acil serviste takip ettiğimiz hastalarda sık karşılaştığımız bir durum olan metabolik asidoz sebepleri ve yönetimini özetlemeyi amaçladım. Ayrıca sık gözlenen klinik durumlardaki tedavi önerilerini derlemeye çalıştım. İyi okumalar dilerim. Metabolik asidoz vücuttaki hidrojen iyonlarının arttığı ve bikarbonatın azaldığı bir süreç olarak tabir edilebilir. Bu süreç sadece kan gazı sonuçlarında pH değerine bakarak açıklanmamalıdır. Metabolik asidozda vücuttaki kompansasyona bağlı olarak pH değeri düşük, normal veya yüksek saptanabilir. Kan pH değerinin

The CPG Guys, Sri & PVSB, are joined in this episode by:Taj Peeran, VP of Digital, Commerce & Brand Engagement at ReckittRahul Kumar Singh: Co-Founder  at SigmoidThis episode is sponsored by Sigmoid.Follow Sigmoid online at: https://www.sigmoid.com/Follow Sigmoid on LinkedIn at: https://www.linkedin.com/company/sigmoid-analytics/Follow Sigmoid on Instagram at: http://instagram.com/sigmoidincFollow Rahul on LinkedIn at: https://www.linkedin.com/in/rksiit/Follow Reckitt Online at: http://reckitt.comFollow Reckitt on LinkedIn at: https://www.linkedin.com/company/reckitt/ Follow Taj on LinkedIn at: https://www.linkedin.com/in/tajpeeran/Taj and Rahul answer these questions:1) Rahul, what was your inspiration to start Sigmoid? Tell us about your data science practice and how have you been delivering impact for CPG customers?2) Taj you of course come from Mead Johnson and Reckitt. What is your role and what does a day in your life look like? Tell us how data and insights shape your marketing strategy?3) Rahul, Many CPG companies are recognizing that the digital world requires a new approach to marketing measurement. Tell our audience how Sigmoid's Multi-Touch  Attribution accelerator helps to optimize marketing spends and drive revenue?4) Taj, how are you leveraging Sigmoid in your everyday life? Do you connect their capabilities directly with ecommerce results? If so, how?5) Rahul - Connect AI to your solutions and how you extract value from AI which I believe is a buzzword in CPG? Taj - please chime in with how your role helps take Reckitt forward on this?6) Rahul - lets jump into 2 others areas - Personalized Recommendations & Customer Life-Time Value (CLTV). Take us through your offerings here.7) Rahul, why do you believe you are different from the many technology engineering analytics providers we talk to? What is your core value proposition and why should someone work with you?Please provide the CPG Guys feedback at http://ratethispodcast.com/cpgguysCPG Guys Website: http://CPGGuys.comDISCLAIMER: The content in this podcast episode is provided for general informational purposes only. By listening to our episode, you understand that no information contained in this episode should be construed as advice from CPGGUYS, LLC or the individual author, hosts, or guests, nor is it intended to be a substitute for research on any subject matter. Reference to any specific product or entity does not constitute an endorsement or recommendation by CPGGUYS, LLC. The views expressed by guests are their own and their appearance on the program does not imply an endorsement of them or any entity they represent. The views expressed by the CPGGUYS, LLC do not represent the views of their employers or the entity they represent. CPGGUYS LLC expressly disclaims any and all liability or responsibility for any direct, indirect, incidental, special, consequential or other damages arising out of any individual's use of, reference to, or inability to use this podcast or the information we presented in this podcast.

The CPG Guys, Sri & PVSB, are joined in this episode by:Frank Cervi: Senior Vice President Supply Chain Strategy and Transformation at Mondelēz InternationalMayur Rustagi: Co-Founder and CTO at SigmoidThis episode is sponsored by Sigmoid.Follow Sigmoid online at: https://www.sigmoid.com/ Follow Sigmoid on LinkedIn at: https://www.linkedin.com/company/sigmoid-analytics/ Follow Sigmoid on Instagram at: http://instagram.com/sigmoidincFollow Mayur on LinkedIn at: https://www.linkedin.com/in/rustagi/Follow Mondelēz International Online at: https://www.mondelezinternational.com/Follow Mondelēz International on LinkedIn at: https://www.linkedin.com/company/mondelezinternational/ Follow Frank on LinkedIn at: https://www.linkedin.com/in/frank-cervi-5304131/Mayur & Frank answer these questions:1) Let's get into the world of Sigmoid, how did the journey start, what was the inspiration and where you are as a company today?2) Frank, as a veteran in the CPG industry, how are data engineering and AI impacting your business? Where does Data fit now, as compared to 5 yrs?3) The intersection of data + AI is sizzling hot these days. AI can help take the most complex data sets and deliver reporting quickly, is this the biggest opportunity in the CPG industry for insights generation?4) Tell us how Sigmoid has differentiated itself from other data analytics companies? What are tangible results of this for CPG brands or retailers? How can this result in stronger downstream ROI generation?5) Solving the digital and analytics scale-up challenge in consumer goods is a real thing. How is Sigmoid helping its customers? Frank - please chime in with how your role helps take Mondelez forward on this?6) What did you find different & compelling in Sigmoid's approach vs. other technology companies that you've dealt with?7) Sigmoid is one of the fastest-growing technology companies in The Americas. What's driving this growth?8) What does the future hold for Sigmoid? What can your clients and those who want to be partners expect from you?Please provide the CPG Guys feedback at http://ratethispodcast.com/cpgguysCPG Guys Website: http://CPGGuys.comDISCLAIMER: The content in this podcast episode is provided for general informational purposes only. By listening to our episode, you understand that no information contained in this episode should be construed as advice from CPGGUYS, LLC or the individual author, hosts, or guests, nor is it intended to be a substitute for research on any subject matter. Reference to any specific product or entity does not constitute an endorsement or recommendation by CPGGUYS, LLC. The views expressed by guests are their own and their appearance on the program does not imply an endorsement of them or any entity they represent. The views expressed by the CPGGUYS, LLC do not represent the views of their employers or the entity they represent. CPGGUYS LLC expressly disclaims any and all liability or responsibility for any direct, indirect, incidental, special, consequential or other damages arising out of any individual's use of, reference to, or inability to use this podcast or the information we presented in this podcast.

You are seeing a young female patient in the clinic with rectal prolapse. When do you offer surgery?  Does she get a perineal approach or a transabdominal approach?  Open or minimally invasive?  Mesh or no mesh?  Sigmoid resection or no resection?  Join Drs. Abelson, Marcello and Aulet as they take us through the wide world of rectal prolapse! Learning Objectives: 1.     Describe the difference between rectal prolapse and hemorrhoidal prolapse 2.     List the different approaches to surgical management of rectal prolapse 3.     Discuss the approach to recurrent rectal prolapse Be sure to check out the associated video below.  Please visit behindtheknife.org to access other high-yield surgical education podcasts, videos and more.  

Contributor: Aaron Lessen, MD Educational Pearls: Sigmoid volvulus occurs when the sigmoid colon twists 180 to 360 degrees 10% of intestinal obstructions in the US; 50-70% of intestinal obstructions worldwide More common in elderly patients with chronic constipation Eventually may lead to bowel perforation, a surgical emergency Treatment is sigmoidoscopy or sigmoid colectomy References Lieske B, Antunes C. Sigmoid Volvulus. [Updated 2021 Aug 11]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2021 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK441925/ Summarized by John Spartz, MS4 | Edited by Erik Verzemnieks, MD The Emergency Medical Minute is excited to announce that we are now offering AMA PRA Category 1 credits™ via online course modules. To access these and for more information, visit our website at https://emergencymedicalminute.org/cme-courses/ and create an account.  Donate to EMM today!

May 11, 2021Ray, Mark, and Scott discuss physician supervision, incident to, and IDTF (Independent Diagnostic Testing Facility), also answer questions from the PRS Community and the Urology Coding and Reimbursement GroupFAQs[14 minutes and 01 Seconds] Our Urology group bills inpatient hospital codes when we get called in for initial visit (99221-99223).  We have always been paid without issues and I have read Medicare guidelines stating this can be billed by each specialty.  In the past few months Aetna started denying these codes stating only one doctor, regardless of specialty is allowed to bill and we were told to bill subsequent day codes.  Now, Anthem is requesting takebacks on payments of these codes dating back to 2019.  I'm looking to see if anyone else is having this issue and is this correct for the payer?Thank you.Carrie[19 minutes and 50 Seconds] Is biofeedback billable service after prostate surgery during the global days?  [26 minutes and 02 Seconds] I need your assistance in coding a 2 surgeon surgery.Summary...I shortened immenselyMy urologist performed cysto open ended stent placement in ureter. The surgery was passed to the general surgeon for robotic lap sigmoid colectomy. The general surgeon dissected the colon from the bladder.My urologist now took over and robotically closed the colovesical fistula. The surgery was passed back to the general surgeon to finish his part.Would I use CPT 51999? and equate it to ? CPT code. The 52005 would be included correct?These combined 2 surgeon surgeries where my urologist performs thecolovesical fistula closure always confuses me.I appreciate your help.Thank you,Linda

The Sigmoid Curve indicates that everything - organizations, relationships, even organisms - follows a phased existence of Development, Introduction, Growth, Maturity, Plateau, and Decline. In this episode, we look further into what these phases mean and how to capitalize on them in your personal and professional life.

Interview with Ville Sallinen, MD, and Alexandre Santos, MD, authors of Comparing Laparoscopic Elective Sigmoid Resection With Conservative Treatment in Improving Quality of Life of Patients With Diverticulitis: The Laparoscopic Elective Sigmoid Resection Following Diverticulitis (LASER) Randomized Clinical Trial

Interview with Ville Sallinen, MD, and Alexandre Santos, MD, authors of Comparing Laparoscopic Elective Sigmoid Resection With Conservative Treatment in Improving Quality of Life of Patients With Diverticulitis: The Laparoscopic Elective Sigmoid Resection Following Diverticulitis (LASER) Randomized Clinical Trial

Most new things in technology turn out to be fads: patterns of talking and doing that come and go without leaving a permanent mark. Microkernels; EPIC architectures like IA-64; object request brokers; and 1990s’-style neural nets are gone, and will not return. Sorry for the deep throwbacks; only time proves which things are fads, so for uncontroversial … https://slack.engineering/how-big-technical-changes-happen-at-slack/ precision and recallsigmoiddiffusion of innovationReact libraryrebuilding our emoji pickershipped a React-only version of Slack on desktopmigrating from PHP to Hack since 2016typesa canonical static vs. dynamic typing debateVitessturned to as we evolve our data sharding strategyour cross-platform C++ client libraryWe took what we learned from the LibSlack effortElixirCassandraWebAssemblyTCRproduct-market fit Different tactics are appropriate for different obstaclesWe’re hiring

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.10.14.338277v1?rss=1 Authors: Dixit, P. D. Abstract: In modern biological physics, there is a great interest in building generative probabilistic models for ensembles of covarying binary variables. A popular approach is to use the maximum entropy principle. Here, one builds generative models that use as constraints lower level statistics estimated from the data. While extremely popular, maximum entropy models have conceptual as well as practical issues; they rely on the modelers' choice of constraints and are computationally expensive to infer when the number of variables is large (n > 100). Here, we address both these issues with Superstatistical Generative Model for Binary Data (SiGMoiD). SiGMoiD is a maximum entropy based framework where we imagine that the data as arising from superstatistical system; individual binary variables are coupled to the same bath whose intensive variables fluctuate from sample to sample. Moreover, instead of choosing the constraints, in SiGMoiD we choose only the number of constraints and let the algorithm infer them from the data itself. Notably, we show that SiGMoiD is orders of magnitude faster than current maximum entropy-based models and allows us to model collections of very large number of binary variables. We also discuss future directions. Copy rights belong to original authors. Visit the link for more info

Improving Gut function TOP to BOTTOM - Organs Involved & Gut-brain connection- Dr. Jason Jones Elizabeth City NC, Chiropractor The food we eat moves through the gastrointestinal tract (a long, connected, hollow tube that starts from the mouth and ends in the anus), and there are lots of organs involved in this process. Along the way, the body absorbs the beneficial part of the food after digestion, giving your nutrients and energy. The remaining part is given out as a waste product. A series of muscles work together to coordinate the moment of food and cells that produce enzymes and hormones involved in the process of digestion. Other “accessory” organs, including the liver, gallbladder, and the pancreas also involved in this process. What organs are involved in the process of digestion? The major organs that are part of the digestive system includes: Mouth Esophagus Stomach small intestine large intestine rectum   These organs work hand-in-hand to convert foods into nutrients and energy that is needed for survival. In the end, it packages the solid waste or stool and gets rid of them through the bowel movement. Mouth This is the starting part of the gastrointestinal tract. It starts working even before you ingest food. The moment you see and smell that warm bread or pasta dish, your salivary glands gets active. After ingesting your food and chewing into smaller pieces, your saliva mixes with the food, breaking it into an absorbable form that your body can use. The tongue helps to move the food to the next organ Esophagus The esophagus is a long tube close to your trachea (windpipe). It receives food from your mouth, and move it to your stomach through a series of muscular contractions called peristalsis. But for this food to move down, the ring-like muscle called lower esophageal sphincter has to relax to allow passage into the stomach. After that, the muscle contracts to prevent backward flow into the esophagus, which may cause acid reflux or heartburn. Stomach The stomach holds food and serves as the mixer and grinder of food. The cells in the lining of this sac-like organ secrete a strong acid and enzymes that are involved in the breakdown of food into a usable form. After proper processing of the food in the stomach, changing it to a consistency of paste or liquid, the content is then moved to the small intestine. Small intestine This organ is a muscular tube 22-foot long, having three segments- the duodenum, jejunum, and ileum. This organ is the “workhouse” of digestion, and most nutrients are absorbed here. Foods are mixed with digestive enzymes released by the pancreas and bile produced from the liver. Peristalsis is also in action in this organ, moving food through as it is being mixed with digestive juices. The duodenum is the first segment and it is largely responsible for continuing the breakdown process. The jejunum and ileum are responsible for the absorption of nutrients into the bloodstream. Once the nutrients have been absorbed, the leftover (the waste) passes into the large intestine or colon. Large Intestine (Colon) The large intestine is a muscular tube that is 6-foot long, and it links the small intestine directly to the rectum. It has segments, including: Cecum Ascending (right) colon Transverse (across) colon, Descending (left) colon, Sigmoid colon This organ is highly specialized and it is responsible for processing waste to ease emptying of the bowels. The stool or waste left over is sent to the colon through peristalsis, and any remaining water is absorbed. The stool is stored in the sigmoid colon until a mass movement pushes it down into the rectum to begin the process of elimination through the anus. Accessory Digestive Organs and functions Liver The liver secretes bile and process the nutrient-rich blood coming from the small intestine. It purifies this blood of impurities before allowing it to travel to the rest of the body. Pancreas The pancreas is the main factory for digestive enzymes that helps to break down carbohydrates, proteins, and fats. These enzymes are secreted into the duodenum segment of the small intestine. Gallbladder This is a sac for the storage of excess bile made in the liver. This bile is released via the bile duct into the small intestine, where it helps to break down fat and move waste out of the liver. Gut-brain connection The brain has a strong connection to the gastrointestinal tract, especially the stomach and small intestine. For example, the thoughts of food alone can trigger the release of the stomach’s juice even before eating. The walls of the digestive system are lined with more than 100 million nerves, starting from the esophagus to the rectum. That’s called the brain in your gut, otherwise known as the enteric nervous system (ENS). So those moments when you’re nervous and feel “butterflies in your stomach,” the ENS is at work. This brain in your gut mainly controls digestion, from swallowing to enzyme release and food breakdown and absorption. Although this ENS is not capable of thought as we know, it has a direct link with our big brain. More so, the ENS can trigger big emotional shifts, especially in people with irritable bowel syndrome (IBS) and bowel problems like diarrhea, constipation, bloating, stomach upset, and pain. Little wonder people with these issues tend to develop depression and anxiety. You can consult Doctor Jason Jones at our Chiropractic office, Elizabeth City, NY, to get mind-body therapies to help your gut function.  

A quick rant about sigmoid functions (a.k.a. S curves) and what that means to my son’s great successes in crawling

On this week's episode, Cam & Otis discuss Sigmoid curves and performance.  We all want to strive for continuous improvement, getting better every day; but unfortunately we do not always have tangible rewards for all of our hard work.  How can you keep your team motivated during the learning phase where there are little to no tangible rewards?  Then once you battle your way into the growth stage, how do you deal with maturity of performance? And what do you do when your team's performance begins to decline?

It's often said that the definition of insanity is doing the same thing over and over and expecting a different result. Everything in life is complex. Take the Sigmoid curve for example - it's the key to growth and transformational change - without change, you're going to get the same results. Listen as Joel Berg, CEO of Hunger Free America and a thought leader, addresses hunger in the U.S. as his passion comes right through the speaker! Joel, Gerry and Phil discuss how hunger does NOT discriminate, the alarming nationwide statistics and how perception is deceiving. Learn more about Hunger Free America at www.hungerfreeamerica.org. Be sure to get caught up on the innovative and inspiring conversation at www.foodfirstmi.org or on Newstalk 760 AM WJR Radio. You can also join the movement for a Food Secure Michigan by filling out our simple form at www.foodfirstmi.org/join-the-movement.

Gill and Matt are gathered around the Leadership Table once more and in this episode they’re discussing the ups and downs of a ride on the Sigmoid Curve. Leaders can face push-back when they attempt to initiate change at a time when the organisation is perceived to be already doing well - at the top of its game, even. How do you respond to those challenges tactfully and get the whole team on-board?Related LinksCharles Handy on WikipediaBuilding Schools for the Future on WikipediaGill’s book, Where Will I Do My Pineapples, gives a deeper look into the building of the new schoolOur intro and outro music by Twin Musicom is licensed under a Creative Commons Attribution licence.

Daniel G. Haller, MD, of the University of Pennsylvania, Philadelphia, joins Blood & Cancer host David H. Henry, MD, also of the University of Pennsylvania, to discuss two real-world gastrointestinal cancer cases and how the latest research should influence the approach to care. Plus, in Clinical Correlation, Ilana Yurkiewicz, MD, of Stanford (Calif.) University talks about pressure from patients to overtreat indolent cancer. This week in Oncology: Perceived discrimination linked to delay in ovarian cancer diagnosis for black women Perceived everyday discrimination was associated with an extended duration between symptom onset and cancer diagnosis in black women with ovarian cancer. Time Stamps: This week in Oncology (04:47) Interview with Dr. Haller (07:27) Clinical Correlation (26:20) Show Notes Patient case #1: Patient presents with a T2 tumor with right-sided colon cancer with invasion of a large right vessel. What is the best management?  The IDEA collaboration: Large analysis to evaluate CAPOX vs. FOLFOX therapy for colorectal cancer and to determine 3 months vs. 6 months of therapy. Researchers at the 2019 American Society of Clinical Oncology annual meeting presented an evaluation of the treatments in stage II colon cancer with high-risk features (Abstract 3501). Definition of high risk: T4, inadequate nodal harvest, poorly differentiated, obstruction, perforation or vascular/perineural invasion. Difficult for pathologists to diagnose T4 disease. The definition of high-risk disease was slightly different in each individual trial. T stage makes the most difference of all. Overall data: Difference in survival is 3% between 3 months and 6 months of therapy. Results by regimen: CAPOX: 3 months vs. 6 months, the difference in survival is almost identical. FOLFOX: 3 months vs. 6 months, difference in survival was 7%, with 6 months being superior. Link: asco.org/239/AbstView_239_257383.html Refresher on grading colorectal cancers: net/cancer-types/colorectal-cancer/stages Patient case #2: A 38-year old woman with past medical history of diverticulitis presents with left lower quadrant pain and is treated with antibiotics but does not improve. She was referred for colonoscopy, which reveals sigmoid polyp; pathology shows moderately differentiated adenocarcinoma. A CT scan is performed, which reveals a lesion that is transmural, circumferential in the sigmoid, and requires surgery. Sigmoid is colectomy performed for a large tumor and serosal and pericolic and immediately adjacent retroperitoneal soft tissue is noted. Other notable features included lymphovascular invasion but no metastases. Genetic testing shows RAS/BRAF negative and MMR analysis notes PMS2 negative.  Concern for Lynch syndrome given right-sided disease, female, large tumor; therefore, genetic testing for Lynch syndrome is recommended. This is important because patient requires more frequent colonoscopies. Work with surgeons to recommend keeping clips in place to minimize area that gets radiation. Approach to treatment: Dr. Haller recommends the “sandwich approach,” in which the patient receives chemotherapy, then radiation, then more chemotherapy. FOLFOX or CAPOX are both chemotherapy options.   Show notes by Ronak Mistry, DO, resident in the department of internal medicine, University of Pennsylvania, Philadelphia. For more MDedge Podcasts, go to mdedge.com/podcasts Email the show: podcasts@mdedge.com Interact with us on Twitter: @MDedgehemonc Ilana Yurkiewicz on Twitter: @ilanayurkiewicz      

With one less Muskrat today, the boys do some bitching about their lives and talk about random shit. Like pretty much always --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app

This episode of CRACKCast covers Rosen’s Chapter 95, Large Intestine. This chapter covers a number of pathologies affecting the large colon, including their associated risk factors & complications.     List features that are typical for IBS. (Describe the Rome IV criteria and list 4 medications used to treat irritable bowel syndrome - show notes) What is the pathophysiology of diverticular disease? List clinical presentations of diverticular disease. How is diverticular disease managed in the ED? Which patients should be admitted to hospital? List 3 complications. List the types and potential causes of large bowel obstruction. What are the four types of GI volvulus? What are the risk factors for developing each type? List the extra-intestinal manifestations of IBD. What are the pathologic and clinical differences between UC and Crohn’s?  List 4 categories of medical therapy for IBD and give one example for each. Describe the radiologic features of toxic megacolon. What the potential causes of toxic megacolon? Which conditions are associated with the development of colonic ischemia? List 4 precipitants of ischemic colitis in the elderly and 3 in young patients List 4 ddx for colitis Differentiate between acute and chronic radiation proctocolitis in pathophys and clinical presentation   Wisecracks:   1) What is Ogilvie’s Syndrome? List 3 RFs 2) Compare AXR findings in SBO with LBO 3)  What is the difference between each Cecal and Sigmoid volvulus on AXR? How is management different? 4) List 3 Perianal complications and 6 Extra-intestinal manifestations of Crohn’s disease. 5) How does adult intussusception differ from peds

This episode of CRACKCast covers Rosen’s Chapter 95, Large Intestine. This chapter covers a number of pathologies affecting the large colon, including their associated risk factors & complications.     List features that are typical for IBS. (Describe the Rome IV criteria and list 4 medications used to treat irritable bowel syndrome - show notes) What is the pathophysiology of diverticular disease? List clinical presentations of diverticular disease. How is diverticular disease managed in the ED? Which patients should be admitted to hospital? List 3 complications. List the types and potential causes of large bowel obstruction. What are the four types of GI volvulus? What are the risk factors for developing each type? List the extra-intestinal manifestations of IBD. What are the pathologic and clinical differences between UC and Crohn’s?  List 4 categories of medical therapy for IBD and give one example for each. Describe the radiologic features of toxic megacolon. What the potential causes of toxic megacolon? Which conditions are associated with the development of colonic ischemia? List 4 precipitants of ischemic colitis in the elderly and 3 in young patients List 4 ddx for colitis Differentiate between acute and chronic radiation proctocolitis in pathophys and clinical presentation   Wisecracks:   1) What is Ogilvie’s Syndrome? List 3 RFs 2) Compare AXR findings in SBO with LBO 3)  What is the difference between each Cecal and Sigmoid volvulus on AXR? How is management different? 4) List 3 Perianal complications and 6 Extra-intestinal manifestations of Crohn’s disease. 5) How does adult intussusception differ from peds

As you can tell from the episode title, this week the Humerus Hacks gals talk about Bowel Obstruction! Sarah and Karen are back in the same city and making more sense than ever. Email us questions at humerushacks@gmail.com Like our Facebook page 'Humerus Hacks' Follow us on Twitter @humerushacks

In this episode, we discuss the problem of how to build a machine that can do anything! Or more specifically, given a set of input patterns to the machine and a set of desired output patterns for those input patterns we would like to build a machine that can generate the specified output pattern for a given input pattern. This problem may be interpreted as an example of solving a supervised learning problem. Checkout the shownotes at: www.learningmachines101.com for a transcript of this show and free machine learning software!

Editor's Audio Summary by Howard Bauchner, MD, Editor in Chief of JAMA, the Journal of the American Medical Association, for the January 15, 2014 issue

Jon Lund talk to Rajeev Singh, Consultant Radiologist at Royal Derby Hospital, UK about common abnormalities see on plain abdominal x-rays, using the ABC structure described in the previous video podcast on the normal plain x-ray. The video podcast covers small and large bowel obstruction and caecal and sigmoid volvulus amongst other topics. Ideal for learning or revision for medical students or foundation doctors and core trainees in surgery (interns and junior residents)