Podcasts about molecular structure

In this episode, Keith gets real about the tough balance between working for money and chasing what you love. He talks about his journey dealing with jobs that paid the bills versus work that brought him joy. Keith shares some eye-opening insights on whether doing something just for the cash or trying to turn your passion into your paycheck is worth it. He even brings in some tips from the pros on how to juggle financial needs while still following your heart. If you've ever felt stuck doing a job you can't stand or dreamt of making money doing what you love, Keith's got some solid advice to help you figure it out. So, tune in for an honest chat about finding that sweet spot between responsibility and fulfillment.   Check out these episode highlights

In this episode examine the key concepts of chemical synthesis, structural determination, and biological function, through the work of R.B. Woodward, who approached organic synthesis as an art form, Dorothy Hodgkin, who used X-ray diffraction to make molecular structures "real" , and Venkatraman Ramakrishnan, whose work on the ribosome revealed how RNA senses base-pairing geometry and ensures fidelity. This episode will explore the tools, challenges, and breakthroughs in these scientific fields. Disclaimer: This podcast is for educational purposes. While every effort has been made to ensure accuracy, the producers are not responsible for errors or omissions. Listeners should seek advice from qualified professionals when necessary.

Does your family have a favourite recipe, a meal that feels like home? For Mario, that was his wife's famous spaghetti and meatballs. But one evening, what should have been a comforting dish left him feeling... uneasy. And then, it happened again and again. Was it just a bad batch—or something far more sinister? In this episode, meet John Franceschini, a forensic chemist with over 30 years of experience in private labs. Outside the reach of police or government, he uncovers the truth about what's really on our plates, and in our drugs.  Join host Kathryn Fox and dive into not one, but two cases of alleged food poisoning, the elusive dangers of synthetic drugs, and why independent forensic labs may be the last line of defense in the search for truth. If you or anyone you know needs help: Lifeline (Crisis support and suicide prevention) 13 11 14 1800 Respect (National sexual assault, family and domestic violence counselling line) 1800 737 732 See omnystudio.com/listener for privacy information.

Episode: 1181 In which Edith Humphry doesn't quite receive the Nobel Prize.  Today, a woman doesn't quite get the Nobel Prize.

Episode 12 of the DNA Papers, is the first of a two-parter, which centers on papers published about the now iconic double helix structure of the DNA molecule. This episode features three publications, all published in the journal Nature, which represent the work of scientists working at King's College London, whose X-ray crystallographic work provided some of the crucial data that supported the new double helix model. Wilkins, Maurice Hugh Frederick, Alec R. Stokes, and Herbert R. Wilson. “Molecular Structure of Nucleic Acids: Molecular Structure of Deoxypentose Nucleic Acids.” Nature 171, no. 4356 (1953): 738–40. Franklin, Rosalind E., and Raymond G. Gosling. “Molecular Configuration in Sodium Thymonucleate.” Nature 171, no. 4356 (1953): 740–41. Franklin, Rosalind E., and Raymond G. Gosling. “Evidence for 2-Chain Helix in Crystalline Structure of Sodium Deoxyribonucleate.” Nature 172 (1953): 156–57. Tune in to listen to our panel of experts in a lively and informative conversation about the place of these papers in the history of our understanding of DNA: Soraya de Chadarevian, University of California, Los Angeles Elspeth Garman, Oxford University Kersten Hall, University of Leeds Jan Witkowski, Cold Spring Harbor Laboratory See also a collection of Resources at https://www.chstm.org/video/144 Closed captioning available on YouTube. Recorded on Nov. 6, 2023.

In this episode, we unravel the olfactory mysteries of an AI breakthrough, a model that predicts smells based on the analysis of molecular structures. Join me for a solo discussion on the potential applications and transformative possibilities in the evolving landscape of artificial intelligence. Invest in AI Box: ⁠https://Republic.com/ai-box⁠ Get on the AI Box Waitlist: ⁠https://AIBox.ai/⁠ ⁠AI Facebook Community Learn About ChatGPT Learn About AI at Tesla

Researchers tune the speed of chirality switchingHello and welcome to the NanoLSI podcast. Thank you for joining us today. In this episode we feature the latest research by Shigehisa Akine at the Kanazawa University NanoLSI.The research described in this podcast was published in Science Advances in November 2023Kanazawa University NanoLSI websitehttps://nanolsi.kanazawa-u.ac.jp/en/Researchers tune the speed of chirality switchingResearchers at Kanazawa University report in Science Advances how they can accelerate and decelerate chirality inversion in large cage molecules using alkali metal ion binding.Chiral molecules can have dramatically different functional properties while sharing identical chemical formulae and almost identical structures. The molecular structure of two types of a chiral molecule – so-called enantiomers – are mirror images of each other where one cannot be superposed on the other any more than your right hand can fit front-to-back on the left. While a lot of chiral molecules are traditionally considered fixed as left- or right-handed, chiral molecules based on helices are known to be able to switch in response to changes in their environment. Now researchers led by Shigehisa Akine at Kanazawa University have demonstrated how environmental changes can also accelerate or decelerate this chiral inversion process, providing “a novel time-programmable switchable system”.The researchers focused their study on “metallocryptand (R6)-LNi3”, an organic molecule featuring metal atoms in a cage-like molecular structure that can exist in one of two possible forms described as the P or M type (right- and left-handed, respectively). In its pure form (R6)-LNi3 has a preferred ratio of P type to M type of 12:88. Starting from a 50:50 ratio, the molecules will flip between one form and the other with a preference for flipping towards the M type to meet that ratio. The researchers measured this change in ratio using NMR and circular dichroic spectroscopy. However, add an alkali metal into the cage cavity and this preference can change.By adding alkali metal ions to the solution of the (R6)-LNi3 the researchers could confirm that the metal ions readily bound to the metallocryptand from the changes in the spectroscopic signatures of the molecules. In addition, the bound ion also shifted the preferred ratio by a margin and with a speed that depended on which alkali metal was used.So what is causing this effect?The researchers attribute the different rates and ratios to differences in binding constants not just between the metal ion and the two forms of the molecule but also a virtual binding constant for the molecule transitioning between the two. The binding between a caesium ion and the P type molecule was more than 20 times greater than that with the M type so the solution eventually switched to a higher proportion of the P type with a P:M ratio of 75:25 over the course of 21 hours. The final ratio with a rubidium ion was similarly bias to the P type reaching a slightly lower ratio of 72:28 but in just 100 minutes. With potassium ion the equilibrium ratio was lower again at 68:32 but reached within just a minute, three orders of magnitude faster than for the caesium ion. The researchers attribute this speed to the large virtual bonding constant with the transitioning molecule.With smaller ions – lithium and sodium ions – the preferred molecular type did not actually change but the final ratio was reached much faster. It is the first time researchers have demonstrated that such chiral inversion can be sped up and slowed down by tuning the molecules environment.“This research can provide a new insight into the development of an on-deNanoLSI Podcast website

In this episode, I dissect the breakthrough AI model's ability to forecast scents based on molecular structures, highlighting its significance in diverse applications and the evolution of AI in sensory prediction. Invest in AI Box: https://Republic.com/ai-box Get on the AI Box Waitlist: ⁠⁠https://AIBox.ai/⁠⁠ AI Facebook Community Learn more about AI in Video Learn more about Open AI

O senso comum costuma dizer que somos seres racionais. Mas, afinal, o que é ser racional? O que é razão? Existe razão sem emoção? O que a ciência pode nos elucidar a respeito?Confira o papo entre o leigo curioso, Ken Fujioka, e o cientista PhD, Altay de Souza.> OUÇA (57min 33s)*Naruhodo! é o podcast pra quem tem fome de aprender. Ciência, senso comum, curiosidades, desafios e muito mais. Com o leigo curioso, Ken Fujioka, e o cientista PhD, Altay de Souza.Edição: Reginaldo Cursino.http://naruhodo.b9.com.br*PARCERIA: ALURAAprofunde-se de vez: garantimos conhecimento com profundidade e diversidade, para se tornar um profissional em T - incluindo programação, front-end, data science, devops, ux & design, mobile, inovação & gestão.Navegue sua carreira: são mais de 1450 cursos e novos lançamentos toda semana, além de atualizações e melhorias constantes.Conteúdo imersivo: faça parte de uma comunidade de apaixonados por tudo que é digital. Mergulhe na comunidade Alura.Aproveite o desconto para ouvintes Naruhodo no link:alura.tv/naruhodo*REFERÊNCIASThe Handbook of Rationalityhttps://books.google.com.br/books?id=xVgjEAAAQBAJ&printsec=frontcover&source=gbs_ge_summary_r&cad=0#v=onepage&q&f=falseThe malpractice of “rationality” in international relationshttps://journals.sagepub.com/doi/10.1177/1043463115593144The teleological science of self-controlhttps://www.cambridge.org/core/journals/behavioral-and-brain-sciences/article/abs/teleological-science-of-selfcontrol/60D69F30FA7F1A94C9CBC8D0E48BA737Molecular (moment-to-moment) and molar (aggregate) analyses of behaviorhttps://onlinelibrary.wiley.com/doi/abs/10.1002/jeab.626?casa_token=YfYOfupyKXQAAAAA:J6_3zhpoFkPAcxPTU-NyiQ7s4oSsMP_AIclAr8WICHhKED_pxxh4sWjjzkkKlssycEg-z_Uid_DvA9UtThe Rationality of Emotionhttps://books.google.com.br/books?hl=en&lr=&id=ohoT1CDor9AC&oi=fnd&pg=PR11&dq=racionality+molar+molecular+conflict&ots=JKiGjJttOP&sig=-RUvx9fcUyEt2iAH43bmzpx8EEE&redir_esc=y#v=onepage&q&f=falsePower, Resistance and Conflict in the Contemporary Worldhttps://books.google.com.br/books?hl=en&lr=&id=xEWPAgAAQBAJ&oi=fnd&pg=PP1&dq=racionality+molar+molecular+conflict&ots=2LUTcgSAVj&sig=pHFZcMoJRi4SFK5uipgHInBfU3U&redir_esc=y#v=onepage&q&f=falseMOLAR AND MOLECULAR ACTIVITYhttps://brill.com/previewpdf/book/9789463008723/BP000006.xml#:~:text=Molar%20lines%20such%20as%20these,the%20molar%20lines%20in%20society.Molar and molecular mobilities: The politics of perceptible and imperceptible movementshttps://journals.sagepub.com/doi/full/10.1177/0263775818776976Molar Function Depends on Molecular Structure of Behaviorhttps://psycnet.apa.org/fulltext/1994-28421-001.pdfNaruhodo #116 - Razão e emoção estão em lados diferentes do cérebro?https://www.youtube.com/watch?v=AKKk4R5f91gNaruhodo #378 - Por que avisos de perigo não são seguidos?https://www.youtube.com/watch?v=lKabJ3lQOHUNaruhodo #259 - Por que as coisas parecem óbvias depois que passamos por elas? - Parte 1 de 2https://www.youtube.com/watch?v=fsgAdq_iu-ANaruhodo #260 - Por que as coisas parecem óbvias depois que passamos por elas? - Parte 2 de 2https://www.youtube.com/watch?v=jWTaLWjT-ZUNaruhodo #340 - Como se constrói a auto-estima?https://www.youtube.com/watch?v=0ULx-CXmh7wNaruhodo #396 - O que fazer frente ao aquecimento global?https://www.youtube.com/watch?v=RchVGabxOdoNaruhodo #393 - A psicologia positiva tem validade científica? - Parte 1 de 2https://www.youtube.com/watch?v=LnSZCHHfoWINaruhodo #394 - A psicologia positiva tem validade científica? - Parte 2 de 2https://www.youtube.com/watch?v=n8h3zC7YLNsNaruhodo #338 - Por que fofocamos?https://www.youtube.com/watch?v=ij9ocesTc50Naruhodo #155 - Tomar decisões cansa o nosso cérebro?https://www.youtube.com/watch?v=tqEfVCT4dGoNaruhodo #222 - Existe cognição quântica?https://www.youtube.com/watch?v=J3jjmo7ly18Naruhodo #379 - Como nós nos tornamos nós?https://www.youtube.com/watch?v=fI9rqAJfcUU*APOIE O NARUHODO PELA PLATAFORMA ORELO!Um aviso importantíssimo: o podcast Naruhodo agora está no Orelo: https://bit.ly/naruhodo-no-oreloE é por meio dessa plataforma de apoio aos criadores de conteúdo que você ajuda o Naruhodo a se manter no ar.Você escolhe um valor de contribuição mensal e tem acesso a conteúdos exclusivos, conteúdos antecipados e vantagens especiais.Além disso, você pode ter acesso ao nosso grupo fechado no Telegram, e conversar comigo, com o Altay e com outros apoiadores.E não é só isso: toda vez que você ouvir ou fizer download de um episódio pelo Orelo, vai também estar pingando uns trocadinhos para o nosso projeto.Então, baixe agora mesmo o app Orelo no endereço Orelo.CC ou na sua loja de aplicativos e ajude a fortalecer o conhecimento científico.https://bit.ly/naruhodo-no-orelo

We discuss the victory over the Greeks in terms of Torah. We also discuss how the letters of the Torah are building blocks for Creation. This class was given at the Phoenix Community Kollel on 12/6/23.

Kanazawa University NanoLSI Podcast:Experiments reveal chilli-sensitive molecular structure fluctuation changes in TRPV1Transcript of this podcast Hello and welcome to the NanoLSI podcast. Thank you for joining us today. In this episode we feature the latest research by Ayumi Sumino at the Kanazawa University NanoLSI alongside Motoyuki Hattori at Fudan University in China, and their colleagues. The research described in this podcast was published in the journal Proceedings of the National Academy of Science in May 2023 Kanazawa University NanoLSI websitehttps://nanolsi.kanazawa-u.ac.jp/en/Experiments reveal chilli-sensitive molecular structure fluctuation changes in TRPV1Researchers at Kanazawa University report high-speed atomic force microscopy experiments that show how ligands associated with stimulating and suppressing activation of the TRPV1 protein increase and decrease the molecule's structural variations. The observations provide insights into how these heat- and chilli-sensing proteins function.The skin senses heat – both from increased temperature and molecules like capsaicin in chillies – through the activation of protein receptors called Transient receptor potential vanilloid member 1 or TRPV1. However, the mechanisms behind the function of TRPV1 have not been clear. Now Ayumi Sumino at Kanazawa University in Japan and Motoyuki Hattori at the Fudan University in China and their colleagues provide important insights into this mechanism. Using high-speed atomic force microscopy to compare the protein with and without stimulating or suppressing molecules – ligands – bound to it, they obtain what they describe as “the first experimental evidence showing the correlation between molecular fluctuation and the gating state (ligand binding)”.So what was already known about this mechanism?Well once activated, the TRPV1 channel opens, allowing ions to permeate and signalling to the nervous system that a noxious stimulant is present. And in 2011 researchers at the Howard Hughes Medical Institute in the US put forward a theoretical basis for the activation of the receptor derived from thermodynamics, a theoretical framework that has since been corroborated by experiment. The idea was that the molecule would respond to heat with a change in heat capacity, which is related to the fluctuations in the molecule's conformation. Structures for the TRPV1 protein were known from previous cryo electron microscopy studies but these did not clarify how the fluctuations in protein conformation might change with stimulating or suppressing molecules, or even whether temperature and chilli sensing shared the same molecular mechanism.Here's where the high-speed atomic force microscopy comes inAtomic force microscopy (AFM) senses the topology of surfaces through the effect of distance on the forces on a nanosized tip positioned directly above the surface. The microscope was first invented in 1986 but gained a new lease of life through work at Kanazawa University that enabled it to capture topologies at high speed thereby providing a window into the dynamics of structures.Sumino, Hattori and colleagues used high-speed AFM to image the TRPV1 receptor both in its unbound state and when bound to ligand molecules that either stimulate, that is agonist molecules, or suppress - antagonist molecules - the protein's activity. They used the molecule resiniferatoxin, which is 1000 times hotter than capsaicin, as the agonist and for the antagonist they used capsazepine, which blocks the pain of capsaicin.From the structures captured the researchers were able to observe fluctuations in the conformation of both the bound and unbound states of TRPV1. They found that resiniferaNanoLSI Podcast website

Dr. Xu Simon is smart. Being that she works in the Boston area, you could say she is "wicked smaaht". She earned her BA in Biochemistry from Rice University and, in 2008, completed her PhD in Biophysical Chemistry and Molecular Structure at MIT. After conducting postdoctoral studies in structural biology at Brandeis University, she served for two years as an American Association for the Advancement of Science (AAAS) Science and Technology Policy Fellow. She currently serves as Chief Technology Officer at Enozo Technologies in Andover, MA and owns an independent speaking, consulting, and mediation business focused on helping executive and technical professionals resonate together for maximal impact.You can find out more about her and check out her Ted Talk at www.XuFits.comTo support your favorite podcast on Mental Health & Meaning, pick up some meaningful The Meaning Project Podcast merch in our store at https://the-meaning-project-podcast.creator-spring.com/And finally, if you would like to support our efforts to improve the podcast and maybe even connect with Dr. Dan in different ways, become a Patron on our Patreon page at: https://www.patreon.com/themeaningprojectpodcastTo contact Dr. Dan go to www.DanielAFranz.com

EP913|12MAR2020 TH| PT2| LORD PRESENTS THE 3D MOLECULAR STRUCTURE OF THE CORONA-VIRUS TO HIS TWO DREADFUL PROPHETS | PROPHET DR. OWUOR Repentance and Holiness Master Website: www.repentandpreparetheway.org Listen To Jesus Is LORD Radio: 1. http://www.jesusislordradio.info 2. https://s3.radio.co/s97f38db97/listen 3. https://streema.com/radios/Jesus_is_Lord_Radio   Sermon Transcripts: https://repentancenews.wixsite.com/repentancenews https://t.me/+WGPnuhxROB1pHYs8 ПОКАЯНИЯ И СВЯТОСТИ: https://repentrussia.webstarts.com Korean YouTube Channel:  https://www.youtube.com/user/parkhsa Repentance & Holiness USA: https://www.youtube.com/channel/UCcAwi5hxz7q3hUWAJ3Q16Qw   FOLLOW REPENTANCE NEWS PODCAST ON OTHER PODCAST PLATFORMS BELOW: 1. TELEGRAM https://t.me/repentancenewspodcast 2. PODBEAN https://repentrussia.podbean.com 3. APPLE PODCASTS https://podcasts.apple.com/gb/podcast/repentance-news-podcast/id1544473658 4. SPOTIFY https://open.spotify.com/show/6KTEehXy1PUoyuN7wOF1SJ 5. AMAZON MUSIC/AUDIBLE https://music.amazon.com/podcasts/ddc393f9-f366-46cd-bd63-d83891bfc9de 6. GOOGLE PODCASTS https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkLnBvZGJlYW4uY29tL3JlcGVudHJ1c3NpYS9mZWVkLnhtbA?sa=X&ved=2ahUKEwjK-_PNysbtAhVHeRoKHR3SCgkQ9sEGegQIARAC 7. PLAYER FM https://player.fm/series/repentance-news-podcast 8. LISTEN NOTES https://www.listennotes.com/podcasts/repentance-news-podcast-bishop-julius-r9ZPRtViCkT/ 9. STITCHER https://www.stitcher.com/s?fid=596030 10. PODCAST ADDICT https://podcastaddict.com/podcast/3189320 11. CASTBOX https://castbox.fm/channel/id1489176?country=gb 12. OVERCAST 13. POCKET CAST 14. CASTRO

For more information, contact us at 859-721-1414 or myhealth@prevmedheartrisk.com. Also, check out the following resources:  ·Jubilee website·PrevMed's website·PrevMed's YouTube channel·PrevMed's Facebook page·PrevMed's Instagram·PrevMed's LinkedIn·PrevMed's Twitter ·PrevMed's Pinterest

All hydrohalic acids, but hydrofluoric acid, are strong acids. Why is that (0:31)? Strong acids fully dissociate and have a large Ka, weak acids only dissociate to a small percentage (1:20). When looking at strength, we are comparing the stability of the conjugate acid/base pair partners (2:00). For binary acids across a period (2:37) as well as down a group (3:09) electronegativity determines acid strength. For oxyacids, we can compare acids with different numbers of oxygen atoms, which affects the inductive effect, as well as resonance structures (4:58). We can also discuss acid strength across a period (6:44) and down a group (7:34). Bases are proton acceptors. Common bases are conjugate bases of weak acids, like carboxylic acids, and amines (7:53).Question of the Day: Acid A has a Ka = 3.5 x 10-8, acid B has a Ka = 1.2 x 10-2. Which acid is HClO, which one is HClO2?Thank you for listening to The APsolute RecAP: Chemistry Edition!(AP is a registered trademark of the College Board and is not affiliated with The APsolute RecAP. Copyright 2022 - The APsolute RecAP, LLC. All rights reserved.)Website:www.theapsoluterecap.comEMAIL:TheAPsoluteRecAP@gmail.comFollow Us:INSTAGRAMTWITTERFACEBOOKYOUTUBE

We're diving into some science of mind! In this one, we dive into two science backed studies: The Placebo Effect and Japanese scientist, Dr. Masaru Emoto's studies on how intention changes the molecular structure of water. What does that mean for us as humans? What are we actually capable of? Support me!: linktr.ee/KeelyMeta Music by the dope: @jazz_june on IG Editor: Sebastian Soto

Elisa Fadda obtained her PhD in 2004 from the Department of Chemistry at the Université de Montréal under Professor Dennis R. Salahub. From May 2004 to May 2008, she worked as a post-doctoral fellow in Dr Régis Pomès group in Molecular Structure and Function at the Hospital for Sick Children (Sickkids) Research Institute in Toronto. From June 2008 until May 2013, Elisa worked as a research associate and honorary research lecturer in Prof Robert J. Woods group in the School of Chemistry at NUI Galway. In 2013 she was awarded a Post-Graduate Certificate in Teaching and Learning in Higher Education from the Centre for Learning and Teaching (CELT) at NUI Galway. In August 2013, Elisa became an Assistant Lecturer in the Department of Chemistry at Maynooth University, taking on a Lecturer position since 2014.You will hear the following terms used during the interview. I've included some descriptions here. Quantum chemistry -The branch of chemistry that apply quantum mechanics to chemical systems, including electronic structure, molecular dynamics and Schrödinger equations.Biophysics – And approach to science that applies methods typically used in physics to study biology and biological systems.Glycoproteins – Proteins which contain oligosaccharide chains (glycans), attached to amino acid side-chains via a covalent bond.Carbohydrates – Molecules (typically biological) composed of Carbon, Hydrogen and Oxygen, typically with a 2:1 Hydrogen:Oxygen atom ratio.Glycan (or polysaccharide) – Compounds made of many monosaccharide subunits, linked via a glycoside bond.N-Glycans – Glycans attached to a protein at an Asparagine residue via an N-glycosidic bond.Sequon – A sequence of amino acids in a protein that serve as a carbohydrate binding site.The carbohydrate is often an N-linked-Glycan.Asparagine, proline, serine, threonine. – Amino acids found naturally in biological proteins. Asparagine, serine and threonine are required in specific combinations to form a sequon, proline must be absent from a sequon.Glycosaminoglycans or mucopolysaccharides- Long, linear glucans consisting of repeating disaccharide units – most commonly uronic acid and an amino sugar.Glycosylation – A reaction in which a carbohydrate molecule is attached to a functional group of another molecule (such as a hydroxyl).  In biology the term typically refers to the carbohydrate being attached to a protein molecule.Folded protein – Proteins have several levels of structure, secondary, tertiary (and arguably quaternary) levels of structure describe how the polypeptide chain forms into specific structures that typically confer functional properties.Cryo-EM – Cryogenic Electron Microscopy studies samples cooled to cryogenic temperatures (-153 oC or lower), while embedded in vitreous water.X-Ray crystallography – A technique which uses X-rays to determine crystal structures, but studying the X-ray diffraction patterns.NMR – Nuclear Magnetic Resonance subjects samples to a strong magnetic fields and measures the resonance pattern of the nuclei. It is widely used to study the structure and dynamics of organic molecules.Spike proteins – More properly ‘Peplomers', spike proteins are glycoproteins that project from the surface of a virus particle lipid bilayer and play an important part in viral infectivity.Coronavirus – One of a group of related RNA viruses that cause respiratory tract infections in birds and mammals. These infections lead to diseases that can have mild effects, or be lethal. The Covid-19 pandemic was caused by a coronavirus, the SARS-CoV-2 virus. The 2002/4 SARS outbreak was caused by the SARS-CoV-1 virus.HIV – The Human Immunoseficiency Virus is two species of lentivirus that if left untreated cause Acquired Immunodeficiency Syndrome (AIDS) in humans.Receptor – A protein embedded in a cell membrane which binds to a specific molecule, or class of molecules.  Once the target molecule is bound, there is typically and effect within the cell to trigger some form of biological process.(viral) Pathogensis – The process by which a disease progresses. Viral pathogensis is specific to a disease caused by a virus.Computer node – Each computer in a connected cluster that are working together.GPUs – Graphics Processing Units are specific electronic circuits that rapidly address memory in order to output images to a display device. Their highly parallel structure makes them efficient at processing algorithms that process large data blocks in parallel.Glycoanalytics – Scientific study of glycosylated molecules, often biological in nature.Neuraminidase, or Sialidase – Are enzymes that cut the glycosidic bonds of neuraminic acids. This action helps viruses move through the respiratory tract mucus and infect host cells. The publication we refer to early on in the discussion is available at https://www.sciencedirect.com/science/article/pii/B9780128194751000560?via%3Dihub.  A full list of Elisa's publications is available at her group website. Elisa is contactable on social media, and you can find her on LinkedIn https://www.linkedin.com/in/elisa-fadda-a012b194/ (although, Elisa admits, she's rarely on LinkedIn)On Twitter, search @ElisaTelisaThe group website is https://efadda73.wixsite.com/elisafadda Our theme music is "Wholesome" by Kevin MacLeod (https://incompetech.com)Music from https://filmmusic.ioLicense: CC BY (http://creativecommons.org/licenses/by/4.0/) Connect with me (Paul) at https://www.linkedin.com/in/paulorange/H.E.L. group can be found at www.helgroup.com online,on LinkedIn at https://www.linkedin.com/company/hel-group/ on Twitter, we're @hel_group, https://twitter.com/hel_groupor search for us on Facebook

This MCAT podcast covers molecular structure and absorption spectra. I discuss 4 different analytical techniques: IR Spectroscopy UV-Vis Spectroscopy Mass Spectroscopy NMR Spectroscopy For comments and concerns, email me: MCATpodcast@medschoolcoach.com Thanks for listening!

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.07.19.205005v1?rss=1 Authors: Wang, Y., Kumar, S., Nisar, A., Bonn, M., Rausch, M. K., Parekh, S. H. Abstract: Blood clots are essential biomaterials that prevent blood loss and provide a temporary scaffold for tissue repair. In their function, these materials must be capable of resisting mechanical forces from hemodynamic shear and contractile tension without rupture. Fibrin networks, the primary load-bearing element in blood clots, have unique nonlinear mechanical properties resulting from their hierarchical structure, which provides multiscale load bearing from fiber deformation to protein unfolding. Here, we study the fiber and molecular scale response of fibrin under shear and tensile loads in situ using a combination of fluorescence and vibrational (molecular) microscopy. Imaging protein fiber orientation and molecular vibrations, we find that fiber orientation and molecular changes in fibrin appear at much larger strains under shear compared to uniaxial tension. Orientation levels reached at 150% shear strain were reached already at 60% tensile strain, and molecular unfolding of fibrin was only seen at shear strains above 300%, whereas fibrin unfolding began already at 20% tensile strain. Moreover, shear deformation caused progressive changes in vibrational modes consistent with increased protofibril and fiber packing that were already present even at very low tensile deformation. Together with a bioinformatic analysis of the fibrinogen primary structure, we propose a scheme for the molecular response of fibrin from low to high deformation, which may relate to the teleological origin of its resistance to shear and tensile forces. Graphical Abstract O_FIG O_LINKSMALLFIG WIDTH=200 HEIGHT=71 SRC="FIGDIR/small/205005v1_ufig1.gif" ALT="Figure 1"> View larger version (21K): org.highwire.dtl.DTLVardef@d72dfborg.highwire.dtl.DTLVardef@10bed75org.highwire.dtl.DTLVardef@12d33aorg.highwire.dtl.DTLVardef@1e9b40f_HPS_FORMAT_FIGEXP M_FIG C_FIG Copy rights belong to original authors. Visit the link for more info

Really just a recap of the previous module + the types of bonding that forms the Double Helix

In this episode, Emma looks at the molecular structure of binary acids and bases for your AP Chemistry exam. She goes through the trends in acid strength and electronegativity of binary compounds in the periodic table. Ideal for preparing you for your AP Chemistry exam. Click here for the full course, or visit this link: http://bit.ly/301Bxii

Cheryl learned the importance of gratitude when her health fell apart around her and she started using it to help herself down the road to healing. So we weren't too surprised when we read that research shows that an "attitude of gratitude" can actually change the molecular structure of your brain? Oh wait . . . NO, it still totally blew our minds! Gratitude changes your brain's STRUCTURE?! WOW, that's wild!You see people talking about gratitude all over the place so it's starting to seem almost fluffy. But gratitude is SO much more than just writing down three things that you're grateful for before bed. Listen to our 3 R's that'll help you add some more gratitude into your day in unexpected ways!

Listen to Dr. Eva Nogales describe how cryo-electron microscopy addresses the challenge of visualizing macromolecular structures.

Explore the real reason why people suffer.

Pastor Kevin Shindoll 1/14/18 2nd Hour

Do you have a set of fundamental principles that help to guide your life? How often do you take time out of your busy day to remain goalless and do nothing? Is it possible for our water and food to change it’s molecular structure when love and energy are directed toward them? What does the Sanskrit word ‘Namaste’ mean and how does it apply to those who cross our paths each day? In the 12th episode of ‘4 X Mindfulness’, Neila and Andy explore these questions by sharing their latest seeds of insight and inspiration related to living a more mindful life. Andy shares a powerful 7-Point Creed that he first learned about from listening to a Tony Robbins podcast from 28 years ago when Tony had interviewed world renown basketball coach, John Wooden. In the Robbins podcast, Wooden discusses the 7-Point Creed that his father taught him to live by. The 7-Point Creed is a special set of guiding principles that are very mindful in nature and can challenge us to reflect on the importance of creating our own creed to live by. Andy also shares an amazing study done by Dr. Masaru Emoto that has to do with how the molecular structure of water changes depending on the emotions and feelings that are cast upon it. In this comprehensive research project, Emoto exposes water to a wide range of both positive and negative emotions and proves how the structure of water can change from fragmented and chaotic forms to being beautifully crystallized in different shapes and sizes. A truly astonishing experiment with paying attention to. As this episode was recorded in Italy, Neila delves into a wonderful Italian expression, ‘dolce far niente’, which literally translates into the ‘Sweetness of Doing Nothing’. She discusses how the Italians embrace this type of attitude each and every day through the interactions that they have with others and how they structure this type of time into their own lives. She challenges everyone of us to think about how we might carve out time in our daily schedules to do the same. Neila also shares the meaning of the Sanskrit word, ‘Namaste’ and why this is so much more than a single word but a beautiful philosophy to embrace in our lives. Neila and Andy hope you find a gem or two that resonates with you in this episode which was recorded in the amazing, rustic, old fishing village of Monterosso, Italy. Bios Neila Steele and Andy Vasily are international educators who have worked at fully authorized IB schools in 4 different countries over the past 16 years (Japan, Azerbaijan, Cambodia, and China). Andy is a consultant, workshop leader, presenter, and speaker. Neila presents and leads multiple workshops in the area of mindfulness. They have devoted themselves to sharing the powerful effects that mindfulness has on promoting greater mental, social, emotional, and physical well-being. Connect With Neila and Andy Neila Twitter: @neilasteele Website: www.mindfulandpresent.com Andy Twitter: @andyvasily Website: www.pyppewithandy.com Themes Discussed: John Wooden, Tony Robbins, Dr. Masaru Emoto, Gratitude, Energy and Love, Mindfulness, Principles to Live By, The Molecular Structure of Water

In our most salacious episode of Whiskey Cats, we taste Colonel E H Taylor Small Batch bourbon, discuss whiskey sticks, whiskey subscriptions, and the chemical makeup of what’s in your glass. Enjoy. Taste: Colonel E H Taylor Small Batch bourbon: https://www.buffalotracedistillery.com/brands/eh-taylor Buffalo Trace: https://www.buffalotracedistillery.com/ Photo: http://whiskeycats.com/post/144273730769/colonel-eh-taylor-small-batch-bourbon http://whiskeycats.com/post/144273818404/the-aftermath-of-recording Science Corner: The Whiskey Stick: http://observer.com/2016/05/this-wooden-stick-will-magically-age-whiskey-15-years-in-only-a-few-of-days/ Whiskey News: Bourbon Every Month: http://www.mouth.com/products/bourbon-every-month?ref=subscribe&utm_source=facebook&utm_medium=cpm&utm_content=alc_mobile&utm_campaign=Alc_LAL_Customers#variant=757143281 Ingenious Glassware Cleverly Embossed With the Molecular Structure of the Drinks They Hold: http://laughingsquid.com/ingenious-glassware-cleverly-embossed-with-the-molecular-structure-of-the-drinks-they-hold/ Music *Norleans Lovas by Jeris featuring unreal_dm ccmixter.org/files/VJ_Memes/33400 CC Attribution Share-Alike (3.0) *Don’t Go Way Nobody *Bessie Smith – “I’m Wild About That Thing”

Did you know that energy actually flows in an acoustical wave? It’s not a linear concept. Raise your vibration. Adjust your body to resonate with the Acoustical Wave of Molecular Structure. How much more ease can you have with your body and your creations when you are creating at the molecular level and utilizing the Acoustical Wave? Join us to learn more! www.exuberantlybeing.com     www.KimMalamaLucien.com   trinarice.accessconsciousness.com

Artist and Scientist Dr. David Goodsell join co-hosts Brian Bartel and Dale Basler on Lab Out Loud this week.  As Associate Professor at the Scripps Research Institute, Dr. Goodsell splits his time on research and science outreach.  His science outreach includes artwork featured online, in a variety of media and even in science museums.  Listen to the show to learn how Dr. Goodsell makes his art, how accurate science is reflected in this art, and how you can use it to teach molecular structure and function. art, biology, books, online resources Show notes at: http://laboutloud.com/?p=2980

Photoinduced ultrafast isomerizations are fundamental reactions in photochemistry and photobiology. This thesis aims for an understanding of the generic forces driving these reactions and a theoretical approach is set up, able to handle realistic systems, whose fast relaxation is mediated by conical intersections. The main focus is on the development of strategies for the prediction and accelerated optimization of conical intersections and their application to artificial compounds with promising physicochemical properties for technical applications as molecular switches. All calculations are based on advanced quantum chemical methods and mixed quantum-classical dynamics. In the first part of this thesis the two-electron two-orbital theory by Michl and Bonacic-Koutecky used in its original formulation to rationalize the structure of conical intersections in charged polyene systems is extended by including the interactions of the active pair of electrons with the remaining closed-shell electrons that are present in any realistic system. A set of conditions, called resonance and heterosymmetry conditions, for the formation of conical intersections in multielectronic systems are derived and verified by calculations on the basic units ethylene, cis-butadiene and 1,3-cyclohexadiene at various geometries and functionalizational patterns. The quantitative results help to understand the role of geometrical deformations and substituent effects for the formation of conical intersections and to derive rules of thumb for their qualitative prediction in arbitrary polyenes. An extension of the rules of thumb to conical intersection seams is formulated. The strategy pursued is to divide the molecular system into basic units and into functional groups. Each unit and its intersection space are treated independently, thereby reducing the dimensionality of the search space compared to the complete molecule. Subsequently, the interconnectivity of the intersection spaces of the different units is determined and an initial guess for the complete seam is constructed. This guess is then fed into a quantum chemistry package to finalize the optimization. The strategy is demonstrated for two multi-functionalized systems, hemithioindigo-hemistilbene and trifluoromethyl-pyrrolylfulgide. In the second part of this thesis state-of-the-art quantum chemical calculations and time-resolved transient and infrared spectroscopy are used to reconstruct the complex multi-channel isomerization mechanisms of hemithioindigo-hemistilbene and trifluoromethyl-indolylfulgide. Both the cis-trans isomerization in hemithioindigo-hemistilbene and the electrocyclic ring closure/opening in indolylfulgide are characterized by a charge transfer in the excited state. The ability of each system to stabilize this charge transfer is essential for the returning to the ground state. The relaxation to the ground state through extended regions of the seam is found to be the decisive step determining the reaction speed and the quantum yield. In the last part of this thesis mixed quantum-classical dynamics simulations at multi-configurational perturbation theory (MS-CASPT2) level, using Tully's fewest switches surface hopping approach, are performed to study the ultrafast photoreactivity of 1,3-cyclohexadiene in the gas-phase. For this purpose a numerical routine for the efficient calculation of non-adiabatic couplings at MS-CASPT2 level is presented. The major part of the excited molecules are found to circumvent the 1B2/2A1 conical intersection and reach the conical intersection seam between the excited state and the ground state instantaneuosly. Time constants for the evolution of the wavepacket on the bright 1B2-state, the relaxation into the 2A1-state and the return to the ground state are extracted. It is demonstrated that the accessibility of the conical intersection seam depends on its energetic and spatial relation to the minimum energy path, as well as on the momentum which is accumulated during relaxation on the excited state potential energy surface.

April 22, 2010 — Scientists at Albert Einstein College of Medicine of Yeshiva University have determined the crystal structures of two key fluorescent proteins — one blue, one red — used to "light up" molecules in cells. Their study appears in the April 22 online edition of Chemistry and Biology, a Cell Press publication.

An Access to Health Experts interview with special guest Dr. West Marrin, author of Universal Water: The Ancient Wisdom and Scientific Theory of Water and Altered Perceptions: Addressing the Real Water Crises.  He discusses several plausible water crises such as a water shortage. He also talks about the structure of water on a molecular level. Access to Health Experts is not only an interview series, it's also a membership website featuring user forums, special reports, monthly teleseminars, and much more. Visit www.accesstohealthexperts.com for more information.

Fri, 1 Jan 1993 12:00:00 +0100 http://epub.ub.uni-muenchen.de/5438/ http://epub.ub.uni-muenchen.de/5438/1/Suenkel_Karlheinz_5438.pdf Sünkel, Karlheinz; Hofmann, Julian Sünkel, Karlheinz und Hofmann, Julian (1993): COORDINATION CHEMISTRY OF PERHALOGENATED CYCLOPENTADIENES AND ALKYNES, XII. SYNTHESIS AND MOLECULAR STRUCTURE OF TRICARBONYL(TETRAKIS(TRIMETHYLSILYL)- CYCLOPENTADIENYL)MANGANESE. In: Journal of

Coordination Chemistry of Perhalogenated Cyclopentadienes and Alkynes, XV[1]. - Systematic Generation of Fivefold Ring-Silylated Cyclopentadienyl Manganese Complexes from [C5Br5]Mn(CO)3. Molecular Structure of [C5Br3(SiMe3)2]Mn(CO)3 [C5Br5]Mn(CO)3 reacts in a sequence of alternate bromine-lithium exchange reactions and electrophilic silylations by SiMe3Cl or SiMe3OSO2CF3 to give [C5Br5-n(SiMe3)n]Mn(CO)3, where n = 1 (1), 2 (2), or 3 (3). A crystal structure determination of 2 shows the two silyl substituents in the relative 1,3-orientation. Addition of one or two equivalents of BuLi and SiMe2HCl to a solution of 3 yields [C5Br2-n(SiMe3)3-(SiMe2H)n]Mn(CO)3 with n = 1 (4) and 2 (5), respectively. If 1 is treated twice with 2 eq. of BuLi and then 2 eq. of SiMe2HCl, a further pentasilylated compound, [C5(SiMe3)(SiMe2H)4]-Mn(CO)3 (6), is obtained. In situ chlorination of [C5(SiMe2H)5]Mn(CO)3 or 6 with PdCl2, followed by addition of MeMgCl, yields after chromatography an inseparable mixture of [C5(SiMe3)4X]Mn(CO)3 compounds, where X = H (7a), SiMe2H (7b), and SiMe3 (7c).

Coordination Chemistry of Perhalogenated Cyclopentadienes and Alkynes, X[1]. - Synthesis and Molecular Structure of a Cyclopentadienyl-1,3-dithiol Complex, [C5Cl3(SH)2]Mn(CO)3 The reaction of [C5Cl4Li]Mn(CO)3 with elemental sulfur leads to [C5Cl4SLi]Mn(CO)3 (1), which is easily oxidized by air to the disulfide (OC)3Mn[C5Cl4S-SCl4C5]Mn(CO)3 (2). Addition of one equivalent of BuLi, followed by an excess of S8 produces the dithiolate [C5Cl3(SLi)2]Mn(CO)3 (3), which yields the dithiol [C5Cl3(SH)2]Mn(CO)3 (5) upon hydrolysis. The molecular structures of 2 and 5 have been determined by X-ray diffraction.

Tue, 1 Jan 1991 12:00:00 +0100 http://epub.ub.uni-muenchen.de/5424/ http://epub.ub.uni-muenchen.de/5424/1/6240.pdf Leidl, E.; Steimann, M.; Sünkel, Karlheinz; Beck, Wolfgang Leidl, E.; Steimann, M.; Sünkel, Karlheinz und Beck, Wolfgang (1991): The reaction of Pt (PPh3)2(C2H4) with tetrachlorocyclopropene. The molecular structure of Pt(PPh3)Cl2(η1-C(Cl)=C(Cl)-C(H)(Cl)PPh3). In: European journal of solid state and inorganic chemistry, Vol. 28, Nr. 5: 841-845 .