Podcasts about chirality

We're taking you through the looking glass to explore 'mirror life': could we be about to flip biology on its head? Like this podcast? Please help us by supporting the Naked Scientists

We love to hear from you. Send us your thought, comments, suggestions, love lettersProfessor Luciano Iess, Planetary Scientist and NASA Exceptional Scientific Achievement MedalistThe Cassini spacecraft's final moments were like a fading heartbeat—one last signal before silence. In this episode, Professor Luciano Iess takes us on a journey across the solar system, from Saturn's icy moons to Venus's runaway greenhouse effect. Hidden oceans beneath alien surfaces, the search for extraterrestrial life, and the delicate balance between planetary protection and bold exploration.Quotable Insights:

On this week's show, Victoria kicks things off with a discussion of Chirality and how the study of the "handedness" of molecules could actually lead to the creation of completely new forms of life. It's a bizarre thought experiment with very real and dangerous consequences. Rachel brings us a creature feature, the fish-scaled gecko. This strange creature has an amazing defense mechanism that is both fascinating and gross. Kirk ends things with a salute to Groundhog Day and he dives into the possible science behind why we think these giant ground squirrels can predict the weather. Support us: patreon.com/strangebynature Email us: contact@strangebynaturepodcast.com Visit us at: strangebynaturepodcast.com

In this episode of Tiny Show and Tell Us, we cover why your body feels so ‘off' at high altitudes and how we've evolved not to detect low oxygen levels but high amounts of carbon dioxide. Then we unpack the confusing world of molecule chirality — what it is, why it matters, and how we evolved to only have ‘left-handed' amino acids but ‘right-handed' DNA and RNA.We need your stories — they're what make these bonus episodes possible! Write in to tinymatters@acs.org *or fill out this form* with your favorite science fact or science news story for a chance to be featured in a future episode and win a Tiny Matters mug!A transcript and references for this episode can be found at acs.org/tinymatters.

On this episode of Loose Canon the team tries to stay on topic and gets sidetracked every step of the way. The lore of Destiny is deep and easy to sink into when its two lore nerds such as these! This week we talk all about the lore book Chirality! If you want more of your favorite Loose Canons go follow their Twitter accounts, and for more information on when we stream or if you have any direct questions to ask us check out the Loose Canon Twitter! The Show:   https://www.twitter.com/LooseCanonShow  The Hosts:   https://www.twitter.com/AnonPig  https://www.twitter.com/Baxt3r  https://www.twitter.com/IshtarColl  https://www.twitter.com/Ryno_666

On this episode of Loose Canon the team tries to stay on topic and gets sidetracked every step of the way. The lore of Destiny is deep and easy to sink into when its two lore nerds such as these! This week we talk all about the first week of Echoes Act 2, as well as the lore book Chirality! If you want more of your favorite Loose Canons go follow their Twitter accounts, and for more information on when we stream or if you have any direct questions to ask us check out the Loose Canon Twitter! The Show:   https://www.twitter.com/LooseCanonShow  The Hosts:   https://www.twitter.com/AnonPig  https://www.twitter.com/Baxt3r  https://www.twitter.com/IshtarColl  https://www.twitter.com/Ryno_666

Join Ellimist and Orchid as they finish reading the lore book "Chirality". The episode was produced by Rindel Zivas. You can find him on Twitter at: @RindelZivas The artwork for the episode is courtesy of Vulshok. You can find him on Twitter at: @VulshokB Guardians of Lore: Website: https://guardians-of-lore.pinecast.co Twitter: @guardians_lore Email: guardians_lore@outlook.com Discord: https://discord.gg/LoreHub You can find other amazing lore content creators at: https://www.reddit.com/r/TheLoreNetwork/ If you feel generous, you can leave us a tip at: https://ko-fi.com/guardians_lore

Join Ellimist and Orchid as they start reading the lore book "Chirality". The episode was produced by Rindel Zivas. You can find him on Twitter at: @RindelZivas The artwork for the episode is courtesy of Vulshok. You can find him on Twitter at: @VulshokB Guardians of Lore: Website: https://guardians-of-lore.pinecast.co Twitter: @guardians_lore Email: guardians_lore@outlook.com Discord: https://discord.gg/LoreHub You can find other amazing lore content creators at: https://www.reddit.com/r/TheLoreNetwork/ If you feel generous, you can leave us a tip at: https://ko-fi.com/guardians_lore

Has JWST found potential alien worlds? Neil deGrasse Tyson and comedian Matt Kirshen learn about exoplanet discovery on the frontier, how higher oxygen gave us dinosaurs, and what type of life could be out there with astrophysicist and astrobiologist Lisa Kaltenegger. NOTE: StarTalk+ Patrons can listen to this entire episode commercial-free here: https://startalkmedia.com/show/distant-aliens-space-dinosaurs-with-lisa-kaltenegger/Thanks to our Patrons Steve Solomon, Jeff Johnson, Duncan Corps, Rodrigo VM, Richard Kashdan, Jenn Long, Jeremy Shimanek, Gary Gaskin, and Longbow81 for supporting us this week.

Episode: 1184 The mirror: something that looks far more obvious than it is.  Today, we look in the mirror and find something strange.

You ever feel like just makin' stuff? Neil deGrasse Tyson and comedian Chuck Nice sit down with the master of making stuff – Adam Savage. They answer fan-submitted questions about creativity, MythBusters, engineering, and a whole lot more.NOTE: StarTalk+ Patrons can listen to this entire episode commercial-free here:https://startalkmedia.com/show/making-stuff-with-adam-savage/

Episode: 1181 In which Edith Humphry doesn't quite receive the Nobel Prize.  Today, a woman doesn't quite get the Nobel Prize.

What is chirality? How do 3D movies work? Why do some drugs have different effects depending on if the molecule is left or right handed? Erin, Kaih and Kade talk chirality on Radio Sci-Lens. Bringing science into focus 4pm Fridays on Radio Fodder (radiofodder.airtime.pro). Follow us on Twitter @radioscilens.

In this podcast episode, MRS Bulletin's Sophia Chen interviews Irmgard Bischofberger of the Massachusetts Institute of Technology about her investigation of how chirality emerges in nature. She uses liquid crystal molecules of disodium chromoglycate in her studies. When the molecules are dissolved in water, they form linear rods. The research group then forces the rods through a microfluidic cell, causing the rods to assemble into spiral structures without mirror symmetry. The achiral structure transformed into a chiral one. What is unique, says Bischofberger, is that the new material is composed of non-chiral building blocks. This work was published in a recent issue of Nature Communications. 

Researchers fix the chirality of helical proteinsHello and welcome to the NanoLSI podcast. Thank you for joining us today. In this episode we feature the latest research by Naoki Ousaka, Mark J. MacLachlan and Shigehisa Akine at the Kanazawa University NanoLSI.The research described in this podcast was published in Nature Communications in October 2023 Kanazawa University NanoLSI websitehttps://nanolsi.kanazawa-u.ac.jp/en/Researchers fix the chirality of helical proteinsResearchers at Kanazawa University report in Nature Communications how they can control chirality inversion in α helical peptides.The function of a protein is determined by its structure – prompting great interest in how to manipulate these structures. The structure is defined not just by the sequence of amino acids that make it, but the shape these acids make – the secondary structure – as well as how that shape is then folded. The most common secondary protein structure is the α-helix, which can coil to the right or left. This coiling direction in turn determines how it engages with other chiral structures, which may be the form of a light beam or another molecule. Although molecular components and environmental factors can favor a particular coiling direction over the other, helical molecules tend to flip between the two coil directions. Now Naoki Ousaka, Mark J. MacLachlan and Shigehisa Akine at Kanazawa University in Japan have shown how they can control and fix the coil direction.Helical proteins are chiral molecules, which means that the molecule's shape cannot be fitted into its mirror image. In nature helical proteins often have other chiral components, such as sugars or amino acids, and these will determine which way the protein coils. However, there is a lot of interest in synthesizing artificial helical proteins that have different chemical components and hence functions not found in nature, and these may not have other chiral components. Nonetheless having both types or “enantiomers” of the chiral molecule can be hazardous because of the significant differences in behavior between the two chiral forms, one of which may be benign or even therapeutic while the other is toxic. Hence, there is demand for other ways of selecting and fixing the chirality.So how did they go about this?Ousaka, MacLachlan and Akine synthesized α helical molecules solely from achiral components. They included bulky segments so that the molecule tended towards the larger rings of the α helical structure, as well as side chains of piperidine – molecular components that are common in pharmaceuticals. These side chains can be cross linked to “staple” the molecule into either the righthanded or lefthanded coil, inhibiting flipping between the two – chiral inversion. Finally they added another molecular component, known as an ester  – the L-Val-OH residue. This would switch the direction of the coil in response to acidic or basic environments due to preferences in the interaction between oxygen atoms in the ester and the amino acid backbone.The researchers used a range of chiral characterization methods including circular dichroism, nuclear magnetic resonance and liquid chromatography. They found that with the molecule stapled just once, it would slow down the flipping between enantiomers by a factor of 106, although this still occurred over minutes. Changing the solution to acid or alkali also successfully determined which enantiomer was favoured. However, stapling the molecule twice slowed down the chirality inversion by a factor of 1012, so that the molecular chirality was stable for years. This increased energy barrier to chirality inversion could then be overcome by heating the sample to very high temperatures to switch betNanoLSI Podcast website

Researchers tune the speed of chirality switchingHello and welcome to the NanoLSI podcast. Thank you for joining us today. In this episode we feature the latest research by Shigehisa Akine at the Kanazawa University NanoLSI.The research described in this podcast was published in Science Advances in November 2023Kanazawa University NanoLSI websitehttps://nanolsi.kanazawa-u.ac.jp/en/Researchers tune the speed of chirality switchingResearchers at Kanazawa University report in Science Advances how they can accelerate and decelerate chirality inversion in large cage molecules using alkali metal ion binding.Chiral molecules can have dramatically different functional properties while sharing identical chemical formulae and almost identical structures. The molecular structure of two types of a chiral molecule – so-called enantiomers – are mirror images of each other where one cannot be superposed on the other any more than your right hand can fit front-to-back on the left. While a lot of chiral molecules are traditionally considered fixed as left- or right-handed, chiral molecules based on helices are known to be able to switch in response to changes in their environment. Now researchers led by Shigehisa Akine at Kanazawa University have demonstrated how environmental changes can also accelerate or decelerate this chiral inversion process, providing “a novel time-programmable switchable system”.The researchers focused their study on “metallocryptand (R6)-LNi3”, an organic molecule featuring metal atoms in a cage-like molecular structure that can exist in one of two possible forms described as the P or M type (right- and left-handed, respectively). In its pure form (R6)-LNi3 has a preferred ratio of P type to M type of 12:88. Starting from a 50:50 ratio, the molecules will flip between one form and the other with a preference for flipping towards the M type to meet that ratio. The researchers measured this change in ratio using NMR and circular dichroic spectroscopy. However, add an alkali metal into the cage cavity and this preference can change.By adding alkali metal ions to the solution of the (R6)-LNi3 the researchers could confirm that the metal ions readily bound to the metallocryptand from the changes in the spectroscopic signatures of the molecules. In addition, the bound ion also shifted the preferred ratio by a margin and with a speed that depended on which alkali metal was used.So what is causing this effect?The researchers attribute the different rates and ratios to differences in binding constants not just between the metal ion and the two forms of the molecule but also a virtual binding constant for the molecule transitioning between the two. The binding between a caesium ion and the P type molecule was more than 20 times greater than that with the M type so the solution eventually switched to a higher proportion of the P type with a P:M ratio of 75:25 over the course of 21 hours. The final ratio with a rubidium ion was similarly bias to the P type reaching a slightly lower ratio of 72:28 but in just 100 minutes. With potassium ion the equilibrium ratio was lower again at 68:32 but reached within just a minute, three orders of magnitude faster than for the caesium ion. The researchers attribute this speed to the large virtual bonding constant with the transitioning molecule.With smaller ions – lithium and sodium ions – the preferred molecular type did not actually change but the final ratio was reached much faster. It is the first time researchers have demonstrated that such chiral inversion can be sped up and slowed down by tuning the molecules environment.“This research can provide a new insight into the development of an on-deNanoLSI Podcast website

References Dr Guerra-notes Schubert. F. 1815 (late March-Early April. Stringt Quartet No. 9 in G minor (D.173) https://youtu.be/piIet7QVLGA?si=FcY0VUUXRPPekKs1 --- Send in a voice message: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/message Support this podcast: https://podcasters.spotify.com/pod/show/dr-daniel-j-guerra/support

In this episode:What is optical isomerismEnantiomersChiral carbon and chiralityAsymmetric carbonOptical Activity and plane-polarized lightBecome a Patreon supporter of the podcast and get more from each episode. patreon.com/chemistrymadesimplePrefer to say a quick 'thank you'? You can buy me a coffee if that's your jam.Check out the Chemistry Made Simple academyFind out more about the Chemistry Made Simple academyContact me:Instagram @chemistrymadesimpleEmail Matthew@ChemistryMadeSimple.netJoin the discussion at the Chemistry Made Simple podcast community.

The ‘scientific' consensus is that the Earth is some billions of years old (on the order of four-and-a-half billion years old) and that the Universe is some fourteen or so billion years old. But Scripture paints a different picture. Which may, should, or must the Christian believe? Is the contention of the so-called ‘scientific community' even reasonable? Which is to say: Does it stand up to scrutiny? Knowledge is warranted true belief, and so it is vitally important to ask upon what warrant the scientists base their beliefs. As we will show in this episode, the Christian position is — unequivocally — that the Earth is ancient in terms of created age and young (some six thousand or so years) in terms of chronological age and that God created all things in six literal, twenty-four-hour days. As to the supposedly ‘scientific' position? Well, it does not stand up particularly well under scrutiny. Subscribe to the podcast here. Show Notes Hexameron [Wikipedia] See Also “Geochronologically Speaking” “James Tour: The Origin of Life Has Not Been Explained” [YouTube] “James Tour & Stephen Meyer Bring Clarity to the Origin of Life Debate (Ep. 1)” [YouTube] Discover Science [YouTube Channel] “Copying and Pasting Passwords” (Relevant for the math involved in the latter part of the episode.) Creation.com CreationWiki.com Further Reading Cosmic background radiation [Wikipedia] DNA [Wikipedia] RNA [Wikipedia] mRNA [Wikipedia] Chirality [Wikipedia] “The Significance of Chirality in Drug Design and Development” “Nature's mirror: The code for chirality” “Understanding the Thalidomide Chirality in Biological Processes by the Self-disproportionation of Enantiomers” Amino Acid [Wikipedia] Abiogenesis [Wikipedia] Neo-Darwinism [Wikipedia] Modern Synthesis [Wikipedia] Hard Problem of Consciousness [Wikipedia] Qualia [Wikipedia] Probability [Wikipedia] Blood Clotting “How it all starts: initiation of the clotting cascade” “Coagulation Cascade” Coagulation [Wikipedia] Vision Visual Phototransduction [Wikipedia] “Phototransduction” Labeling of Fertilizer [Wikipedia] Deoxyribose [Wikipedia] Organophosphate [Wikipedia] Books Darwin's Black Box: The Biochemical Challenge to Evolution by Michael Behe Theistic Evolution: A Scientific, Philosophical, and Theological Critique edited by J. P. Moreland, et al. Also available on ChristinBook.com. Parental Warnings None.

A discussion on the purity standards and lab tests our oils go through.

In this podcast episode, MRS Bulletin's Laura Leay interviews Monica Olvera de la Cruz of Northwestern University and her colleagues who gained insight into biochirality. By analyzing self-assembly for a series of amphiphiles, Cn-K, consisting of an ionizable amino acid [lysine (K)] coupled to alkyl tails with n = 12, 14, or 16 carbons, the researchers found the degree of ionization is what controls the shape. They incorporate this phenomenon into a membrane energetics model. Furthermore, their experimental techniques show that the nanoscale structure of the chiral assemblies can be continuously controlled by solution ionic conditions. The model moves researchers one step closer to building entire cells in the laboratory and could lead to the development of nanotechnology such as drug delivery and electronics. This research is published in a recent issue of ACS Central Science (https://doi.org/10.1021/acscentsci.2c00447).

Galaxy Spin Classification I: Z-wise vs S-wise Spirals With Chirality Equivariant Residual Network by He Jia et al. on Monday 10 October The angular momentum of galaxies (galaxy spin) contains rich information about the initial condition of the Universe, yet it is challenging to efficiently measure the spin direction for the tremendous amount of galaxies that are being mapped by the ongoing and forthcoming cosmological surveys. We present a machine learning based classifier for the Z-wise vs S-wise spirals, which can help to break the degeneracy in the galaxy spin direction measurement. The proposed Chirality Equivariant Residual Network (CE-ResNet) is manifestly equivariant under a reflection of the input image, which guarantees that there is no inherent asymmetry between the Z-wise and S-wise probability estimators. We train the model with Sloan Digital Sky Survey (SDSS) images, with the training labels given by the Galaxy Zoo 1 (GZ1) project. A combination of data augmentation tricks are used during the training, making the model more robust to be applied to other surveys. We find a $sim!30%$ increase of both types of spirals when Dark Energy Spectroscopic Instrument (DESI) images are used for classification, due to the better imaging quality of DESI. We verify that the $sim!7sigma$ difference between the numbers of Z-wise and S-wise spirals is due to human bias, since the discrepancy drops to $

Ya estamos en octubre. Y, como es habitual en el Sonidos y Sonados, cambio de mes, cambio de sintonía. Todos los programas de octubre comenzaran con “Turia river killed the radio star” del dúo valenciano Le Garçon Rêvé, luego otra gente que también podrían haber sido sintonía este mes, Epoch of Chirality, Igor, Marien Novi […]

Podcast time for the show that was broadcast on Saturday. Music from: #LeviNice Monster Truck Seething Akira Wicked Smile Papa Shango The Gloom In The Corner The Maine Taking Back Sunday and Charlotte Sands Atheana Honeycub Beyond the Black Killer Kings H.E.A.T The Plague #TheRetaliators featuring Motley Crue Asking Alexandria Ice Nine Kills And From Ashes to New Meteora Guardian of Lightning Fallen Mafia Alien Weaponry Epoch of Chirality

Topic discussing: The Realm of Dreams: Is there any Meaning? The Homeless in the Heat Presenter: Samail Ahmad Bashir Ahmed Segment 1: The Realm of Dreams: Is there any Meaning Gist of the story: Since time immemorial, dreams have been considered a special means of communion with the Divine Being. It is considered a means through which a person can be illuminated with the light of knowledge, righteousness and truth. Dreams are a portal to an unknown world and this concept forms the basis of a long-awaited Netflix adaptation of Neil Gaiman's comic book series, The Sandman. In these series, the king of dreams, Morpheus, rules over the realm of dreaming and so begets many questions about the realities of dreams. Therefore, in this segment, we will be exploring the origins and meaning of dreams, whilst also emphasising their significance in Islam. Segment 2: Exploring the Emergence of Chirality in Nature, Biological Life and Medicinal Drugs: Gist of the story: Did you know that both lemons and oranges constitute the exact same compound, limonene, yet, they smell so different due to one of the molecules spinning to the right, whilst the other spinning on the left side? Well, the preference for a certain side or otherwise known as chirality, can also be found in nature and biological life. In 1848, Louis Pasteur first discovered chirality in the salt of tartaric acid where he was able to isolate two sets of crystals, each a mirror image of the other. Since then, thousands of chiral molecules have been discovered around the world with chirality being found in amino acids which create proteins and even in medicinal drugs (thalidomide being a prominent example). Thalidomide, when it spins to the right, is instrumental in treating morning sickness, but if it spins to the left can lead to devastating effects such as birth defects. In this segment, we will be discussing the essence of chirality in nature, biological life and medicinal drugs, whilst highlighting its importance in Islam. Segment 3: The Homeless in the Heat Gist of the story: We tend to think about rough sleepers in the winter, but what about during summer heatwaves? Especially with homelessness increasing amid the cost-of-living crisis. This segment will look at raising awareness on homelessness: why it's happening and how we can help it. Guests include: Prof Tom Stoneham Prof Matt Jones Dr Simon Cotton Prof Laurence Barron Prof David Parker Dr Jess Wade Petra Salva Rafa Ahmed Gemma Thapermall Researchers: Maleeha | Anoosha | Ine | Basil Produced by: Rameen Masood & Maleeha Mahmood

We talk about chirality, how some molecules have left-handed properties and others have right-handed properties.  It turns out that electrons, carrying energy and information vital to life, spin in different directions when interacting with these two types of molecules and harnessing that effect could lead to big advances in energy production, agriculture and medicine.  Our panelists are two of the leading researchers in the field:  Dr. Ron Naaman of the Weizman Institute of Science and Dr. Moh El Naggar of the University of Southern California.  In a “Town Talk” at the Transfer Warehouse in Telluride, they were interviewed by award-winning broadcast journalists Judy Muller and George Lewis.

This episode is also available as a blog post: https://ungroovygords.com/2022/02/27/chirality-preponderance-haibun-poetry%ef%bf%bc/ --- Send in a voice message: https://anchor.fm/groovygords/message

Rich How of EPOCH OF CHIRALITY chats with Jon about alien sounds, sci-fi movies, the fun part of the pandemic, Star Trek vs Star Wars; two tracks 'Labyrinth', 'Pyramid Cybergod', and his latest record, Nucleosynthesis. 'Labyrinth' https://youtu.be/aoxACwFr4Yo 'Lost In Echoes' https://youtu.be/j6MNqPfIe74 Find out more about EPOCH OF CHIRALITY at: https://epochofchirality.com/ -------------------------------------------------------------------------------------------------------------------------- Jon Harris of The Rock Metal Podcast interviews rock and metal bands to get the scoop on their latest two songs and news! Want to be on The Rock Metal Podcast? Email Jon at TheRockMetalPodcast@gmail.com Want to support The Rock Metal Podcast? Donate here: https://www.paypal.me/JonJHarris Want to be on our newsletter list? Provide your email address at https://mailchi.mp/af7a2332e334/therockmetalpodcastnewsletter

I caught up with Rina last year where we had a really interesting conversation  covering a host of topics, from being a woman scientific entrepreneur, to the challenges in developing a business  over  the past 20 years, to the use of Chiral Technology in Drug development.We discussed...Who are BioTools 00:52Why did Rina launch BioTools 01:56What was it like being a woman working in Pharma 20 years ago? 03:49What changes has Rina seen over the past  20 years in relation to Women in Science?  08:42How has Rina developed the culture of here business? 10:46What were the biggest challenges did Rina have developing the business? 12:20What advice would she give people starting up their own business? 16:52What changes has Rina seen in Chiral Technology and why is it still relevant? 20:46What does Rina see the future for Chiral Technology 23:27What solutions do Biotool offer which are unique? 25:15You can find out more about BioTools here https://biotools.us/You can view  this and many more interviews and demos from  many other industry experts across Pharma, Bio-Pharma and Life Science on my YouTube channel RSK Life Science Media https://www.youtube.com/channel/UC9vdET2xLlGweqveW6JmQdQ#WomenInScience, #WomenInStem, #Science, #Entrepreneurship, #spectroscopy, #chirality, #pharma, #chiralmolecules, #VCD, #VibrationalSpectroscopy,,#mentor, #payitforward, #medchem, #WomenDoingScience, #WomenInChemistry, #WomenInSpectroscopy,

Visit https://thermofisher.com/bctl to register for your free Bringing Chemistry to Life T-shirt and https://www.alfa.com/en/chemistry-podcasts/ to access our episode summary sheet, which contains links to recent publications and additional content recommendations for our guest.The only chemistry we know is what we can experience on our planet, or is it? Brett McGuire is among the pioneers looking beyond the Earth's atmosphere and discovering a surprising and fascinatingly complex chemical world that defies imagination and provides intriguing new insights into the origin of the chemistry we know. In one of our most fascinating episodes yet, Paolo and Brett discuss astrochemistry, the study of chemistry in outer space. Chemistry in space is unique because it is atmosphere and solvation free, and temperature is really low. By scanning radio telescope spectra, astrochemists are discovering hundreds of complex organic molecules in the spaces between stars and are developing intriguing new theories on the origin of our chemical reservoir, the reasons for biological L- chirality, and how life could vary in different parts of the universe. If you're tempted to dismiss this as mere curiosity, you will be surprised by how efforts to study chemistry happening light years away from our planet are often the key to revolutionizing chemistry here on Earth.

Christine Johnson, Empowerment Radio Guest Speaker - Michael Devon Alston Topic - Part 2 The Tabernacle Christian: What is Outside of your Temple? Luv Radio Network

You will hear the following terms used during the interview. I've included some descriptions here. Chirality – Chirality is a feature where an object can be distinguished from a mirror-image version of itself (for instance left and right gloves, or shoes). In chemistry, chirality is often due to the presence of an asymmetrical carbon atom. Chiral isomers are identified as either L-type or D-type, based on how polarized light is rotated when passing through a molecule.Superstructure – In the context of this discussion “When the structures become way, way bigger than the building blocks, you can call the superstructures.” They represent massive polymers of the base construction moleculesNanomaterials / Nanoparticles – A term used to describe substances where the base unit is small – between 1 nm - 100 nm along one or more dimensionsAmyloid beta-peptide (also known as Abeta, or Aβ) – Peptides between 36-43 amino acids long that form insoluble amyloid plaques in the brains of people suffering from Alzheimer's disease. Although the specific role of Amyloid plaques in Alzheimer's disease is not fully understood, it is widely accepted that they are responsible for the pathology of the disease.Peptide – A short chain of 2-50 amino acids, linked by a peptide bond. A dipeptide has two amino acids in the chain, a tripeptide has three amino acids, and so on.Hydrophobic pockets – When folded into a functional configuration, the amino acids of a protein can be brought into physical proximity. When the majority of amino acids surrounding an ‘opening' in the surface of the protein are hydrophobic, it creates a region that is unattractive to hydrophilic molecules. As the majority of biological systems are water-based, this hydrophobic region stimulates other hydrophobic regions of suitable molecules to bind. This then typically leads to downstream activation or effectCatalytic triads - a set of three coordinated amino acids that can be found in the active site of some enzymes. Catalytic triads are most commonly found in hydrolase and transferase enzymes.Antimicrobial resistance – This is an evolutionary process where bacteria become immune to the effects of antimicrobial agents (such as antibiotics). Typically this is caused by exposure are designed to kill bacteria. To do this, the bacteria need to be exposed to the agents at sub-lethal levels. As antimicrobial agents accumulate in the environment, it is believed that this provides an opportunity for bacteria to be exposed at sub-lethal levels, which accelerates the rate at which the bacteria develops resistance to the antimicrobial.We discussed the drawing of Alice going through the looking glass during our discussion, you can see it at https://www.sciencephoto.com/media/995913/view/through-the-looking-glass-alice-pushes-through-the-mirror.Silvia also mentions an article in the journal ACS Nano, you can find that at: https://pubs.acs.org/doi/10.1021/acsnano.0c09386#Silvia is contactable on social media, you can find her on LinkedIn https://www.linkedin.com/in/silvia-marchesan-2590712/On Twitter, search @MarchesanLabThe group website is www.marchesanlab.com Our theme music is "Wholesome" by Kevin MacLeod (https://incompetech.com)Music from https://filmmusic.ioLicense: CC BY (http://creativecommons.org/licenses/by/4.0/) Connect with me (Paul) at https://www.linkedin.com/in/paulorange/H.E.L. group can be found at www.helgroup.com online,on LinkedIn at https://www.linkedin.com/company/hel-group/ on Twitter we're @hel_group, https://twitter.com/hel_groupor search for us on Facebook 

Hanieh Sigari, an entrepreneur, biochemist, and anti-aging disruptor, shares how her journey as an entrepreneur started, her decision-making process in going from a new business venture to the next, and her take on approaching a career in this modern age. Timecode Guide 01:17 About Hanieh Sigari 02:10 About Qyral and the Definition of Chirality 03:19 Business Ventures: Health Care Start-Up on Aging 04:59 Business Ventures: E-Commerce Fulfillment and Logistics 05:39 Business Ventures: Qyral 06:15 Dealing with Burnouts 08:07 E-Commerce Fulfillment and Logistics Business Learnings 09:53 Multilevel Marketing or Network Marketing Business Model 10:31 Her Inspiration in Being in Business 13:49 What makes Qyral different? 15:55 What would your billboard say that screams a motto that you love? 16:40 Influential persons in the concept of “There’s no such thing as failure” 17:50 The number one thing to know about setting themselves up for success and showing up authentically to who they are as human beings 20:00 When a belief is controversial 21:37 What to change about the way people are approaching their careers? 24:12 How can people continue to bring more good into their life? 24:38 How to Connect with Hanieh Sigari If you want to know more about Hanieh Sigari, click the links below. Hanieh Sigari's Website Hanieh Sigari's Instagram Hanieh Sigari's Facebook --- Support this podcast: https://anchor.fm/shareinspirerepeat/support

Howard Jones from Light The Torch (and ex-Killswitch Engage) is back on the show! This time we're chatting about the new LtT album You Will Be The Death Of Me, Camping, 80's Fashion, touring with the Killswitch guys again, and more. JT & Jesse from ERRA discuss their first band. Then I recommend Epoch of Chirality. Howard Jones  New Record - Facebook Erra  Website - New Album Epoch of Chirality  New Record - Facebook

A new monthly mix featuring the best new music from across House, Trance, and electronic genres, mixed by HNNRS from Miami, USA. This mix features @LeYouth @NoraEnPure @EliandFur @MikeMago @GorgonCity @FrankyWah.Follow @DJHNNRS on Soundcloud and Instagram. Visit www.HNNRS.com for videos, gigs, bookings.  Subscribe to listen on Apple Podcasts, Google Podcasts, Amazon Music, Stitcher, iHeartRadio, Pandora, Overcast, Castro, Castindex and Podfriend, TuneIn + Alexa, Podcast Addict, Podchaser, Pocket Casts, Deezer, Listen Notes, Player FM, Podcast Index. ---1. Colour - @LeYouth2. Enchantment - @NoraEnPure3. Adagio for Square - @Worakls.music4. Renaissance (@djManuelRiva Remix) - @MaximLany5. Soothing Tension - @realPassenger106. About Us - @LeYouth7. Why Do We Shake In The Cold? (@VintageCulture Remix) - @_Elderbrook8. Eyes On Me - @TCTSoffical, @AnabelEnglund, @MikeMago9. 8 (Circle) - @NickChicane10. Otherside (@NilsHoffmannMusic Remix) - @EliandFur11. Piece Of Your Heart (@CYA Remix) - @MeduzaMusic, @Goodboysoff12. Chirality x Lies Deception And Fantasy - @MarVeiMusic @ChrisLake @LeeFoss14. Should Have Seen It Coming - @FrankyWahmusic, @AETHOmusic15. Dark Magic - @PROFFmusic16. Easier - @CamelPhatmusic17. Alive - @Paxmusic & @GorgonCity18. Oceanic (JeromeIsmaAe Mix) - @_Tranquility_Base, @AboveandBeyond19. Electric Mama - @JamieJonesMusic & @Harvy_Valencia_

From winter gloves and people with inverted organs to the effects of molecular mirror images. Chirality can be found everywhere, so it is high time to talk about it. If you would like to share feedback or have a suggestion for a topic, I can now be reached on twitter under @ChemistryinEve1. Alternatively, you can send an email to chem.podcast@gmail.com. Sources Wikipedia entries on Chirality and Enantiomers · https://en.wikipedia.org/wiki/Chirality · https://en.wikipedia.org/wiki/Chirality_%28chemistry%29 · https://en.wiktionary.org/wiki/chirality · https://en.wikipedia.org/wiki/Enantiomer · https://de.wikipedia.org/wiki/Enantiomer · https://de.wikipedia.org/wiki/Chiralit%C3%A4t_(Chemie) Textbook Entries on Chirality · General Chemistry by D. D. Ebbing 5th Ed. 1996 ISBN 0-395-74415-6; p. 1002ff · Organic Chemistry by Clayden, Warren & Wothers; p. 382ff Thalidomide and its effect on pregnant women · https://de.wikipedia.org/wiki/Thalidomid · https://en.wikipedia.org/wiki/Thalidomide About the people with inversed organs · https://en.wikipedia.org/wiki/Situs_inversus · https://de.wikipedia.org/wiki/Situs_inversus Origins of L-amino acids Meteorite Theory (extraterrestrial influence) · https://www.nature.com/articles/38460?error=cookies_not_supported&code=ab67c03e-1459-4eeb-a6b6-d03ee81fde42 à Meteor · https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667035/ · https://en.wikipedia.org/wiki/Murchison_meteorite Asymmetric Synthesis of Chirality · https://www.onlinelibrary.wiley.com/doi/10.1002/%28SICI%291521-3773%2819991203%2938%3A23%3C3418%3A%3AAID-ANIE3418%3E3.0.CO%3B2-V · https://pubmed.ncbi.nlm.nih.gov/11848967/ · https://www.sciencedirect.com/science/article/abs/pii/S0959943603704878?via%3Dihub · https://www.onlinelibrary.wiley.com/doi/10.1002/anie.200290005

Von Handschuhen über Menschen mit umgedrehten Organen bis hin zu den Effekten von molekularen Spiegelbildern, Chiralität kann man überall finden, daher ist es jetzt höchste Zeit ein paar Worte darüber zu verlieren. Willst du einen Kommentar zu dieser Episode oder zu diesem Podcast abgeben oder hast du einen Vorschlag für ein Thema, dann gibt es zwei Möglichkeiten. Entweder schreibe mir auf Twitter unter @alltagschemie oder schicke mir einfach altmodisch eine email auf chem.podcast@gmail.com. Quellen: Wikipedia entries on Chirality and Enantiomers · https://en.wikipedia.org/wiki/Chirality · https://en.wikipedia.org/wiki/Chirality_%28chemistry%29 · https://en.wiktionary.org/wiki/chirality · https://en.wikipedia.org/wiki/Enantiomer · https://de.wikipedia.org/wiki/Enantiomer · https://de.wikipedia.org/wiki/Chiralit%C3%A4t_(Chemie) Textbook Entries on Chirality · General Chemistry by D. D. Ebbing 5th Ed. 1996 ISBN 0-395-74415-6; p. 1002ff · Organic Chemistry by Clayden, Warren & Wothers; p. 382ff Thalidomide and its effect on pregnant women · https://de.wikipedia.org/wiki/Thalidomid · https://en.wikipedia.org/wiki/Thalidomide About the people with inversed organs · https://en.wikipedia.org/wiki/Situs_inversus · https://de.wikipedia.org/wiki/Situs_inversus Origins of L-amino acids Meteorite Theory (extraterrestrial influence) · https://www.nature.com/articles/38460?error=cookies_not_supported&code=ab67c03e-1459-4eeb-a6b6-d03ee81fde42 à Meteor · https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667035/ · https://en.wikipedia.org/wiki/Murchison_meteorite Asymmetric Synthesis of Chirality · https://www.onlinelibrary.wiley.com/doi/10.1002/%28SICI%291521-3773%2819991203%2938%3A23%3C3418%3A%3AAID-ANIE3418%3E3.0.CO%3B2-V · https://pubmed.ncbi.nlm.nih.gov/11848967/ · https://www.sciencedirect.com/science/article/abs/pii/S0959943603704878?via%3Dihub · https://www.onlinelibrary.wiley.com/doi/10.1002/anie.200290005

Jess Wade from Imperial College London’s Blackett Laboratory kicks off Season 3 with expert insights on OLEDs, chiral materials, and the not-so-clear-cut relationship between science and equity. Through the lens of SPIE’s very first Diversity Outreach Award winner, listeners will enjoy a candid conversation on topics ranging from polymer conjugation to breaking biases in STEM and beyond.Sponsored by:MKS Instruments - www.newport.comHamamatsu Corporation - www.hamamatsu.comAll Things Photonics is produced by Photonics Media and airs bi-weekly, on Tuesdays. Find links to the stories mentioned in the episode on our website, www.photonics.com/podcast.The podcast has been named a finalist in two categories — Best Science & Medical Podcast and Best Technology Podcast — for The Publishers Podcast 2021 Awards. Season 1 received an Honorable Mention for excellence in engaging content from the 2020 Folio Eddie Awards.

Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay.WISHING EVERYONE A VERY MERRY CHRISTMAS!! To start episode, I will be emphasizing the essence of this great holiday and festive seasonBonding fosters complete, proper interaction of drugs with receptors. The most important and major bonds to be known are Covalent, Electrostatic and Hydrophobic. Strongest bonds are covalent, many a times irreversible in nature. This concept will be clear with  good examples.Next I will be talking about Electrostatic bonds, Their strength may vary from very strong to weak to very weak, Last to discuss will be hydrophobic bonds. A relation of drug selectivity will be stated along with bonding. Next I will cover a word about inert substances or drugs.Drug shape along with characteristics of "Chirality" or "Stereoisomerism".All the concepts will be crystal clear with apt examples. A fact about current overpowered use of racaemic mixture of drugs will be discussed along with the basis to justify the rationality of this point of talk.Then lastly, I will talk about Rational Drug designing, in very brief though its quite important topic of conversation, I will be talking about most important points and the importance of rational drug designing.With a promise to continue such informative crispy conversations without any delay, no ideas to hamper your holiday, Christmas eve plans, with a little sneak peak about next episode, time to wave y'all HAPPY CHRISTMAS again!! GOD BLESS ALL !! For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also. You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. WISHING EVERYONE A VERY MERRY CHRISTMAS!! To start episode, I will be emphasizing the essence of this great holiday and festive season Bonding fosters complete, proper interaction of drugs with receptors. The most important and major bonds to be known are Covalent, Electrostatic and Hydrophobic. Strongest bonds are covalent, many a times irreversible in nature. This concept will be clear with good examples. Next I will be talking about Electrostatic bonds, Their strength may vary from very strong to weak to very weak, Last to discuss will be hydrophobic bonds. A relation of drug selectivity will be stated along with bonding. Next I will cover a word about inert substances or drugs. Drug shape along with characteristics of "Chirality" or "Stereoisomerism".All the concepts will be crystal clear with apt examples. A fact about current overpowered use of racaemic mixture of drugs will be discussed along with the basis to justify the rationality of this point of talk. Then lastly, I will talk about Rational Drug designing, in very brief though its quite important topic of conversation, I will be talking about most important points and the importance of rational drug designing.With a promise to continue such informative crispy conversations without any delay, no ideas to hamper your holiday, Christmas eve plans, with a little sneak peak about next episode, time to wave y'all HAPPY CHRISTMAS again!! GOD BLESS ALL !! For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also. You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

Welcome all to IS PHARMACOLOGY DIFFICULT Podcast! I am Dr Radhika Vijay. WISHING EVERYONE A VERY MERRY CHRISTMAS!! To start episode, I will be emphasizing the essence of this great holiday and festive season Bonding fosters complete, proper interaction of drugs with receptors. The most important and major bonds to be known are Covalent, Electrostatic and Hydrophobic. Strongest bonds are covalent, many a times irreversible in nature. This concept will be clear with good examples. Next I will be talking about Electrostatic bonds, Their strength may vary from very strong to weak to very weak, Last to discuss will be hydrophobic bonds. A relation of drug selectivity will be stated along with bonding. Next I will cover a word about inert substances or drugs. Drug shape along with characteristics of "Chirality" or "Stereoisomerism".All the concepts will be crystal clear with apt examples. A fact about current overpowered use of racaemic mixture of drugs will be discussed along with the basis to justify the rationality of this point of talk. Then lastly, I will talk about Rational Drug designing, in very brief though its quite important topic of conversation, I will be talking about most important points and the importance of rational drug designing.With a promise to continue such informative crispy conversations without any delay, no ideas to hamper your holiday, Christmas eve plans, with a little sneak peak about next episode, time to wave y'all HAPPY CHRISTMAS again!! GOD BLESS ALL !! For all the updates and latest episodes of my podcast, please visit www.ispharmacologydifficult.com where you can also sign up for a free monthly newsletter of mine. It actually contains lot of updates about the medical sciences, drug information and my podcast updates also. You can follow me on different social media handles like twitter, insta, facebook and linkedin. They all are with same name "IS PHARMACOLOGY DIFFICULT". If you are listening for the first time, do follow me here, whatever platform you are consuming this episode, stay tuned, do rate and review on ITunes, Apple podcasts, stay safe, stay happy, stay enlightened, Thank you!!

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.11.11.377721v1?rss=1 Authors: Kim, S. J., Ko, W.-K., Han, G. H., Lee, D., Lee, Y., Sheen, S. H., Hong, J. B., Sohn, S. Abstract: Neuroinflammation forms a glial scar following a spinal cord injury (SCI). The injured axon cannot regenerate across the scar, suggesting permanent paraplegia. In this study, we report that d-chiral glutathione (D-GSH) suppresses the inflammatory response after SCI and leads to axon regeneration of the injured spinal cord to a greater extent than l-chiral glutathione (L-GSH). After SCI, axon regrowth in D-GSH-treated rats was significantly increased compared to that in L-GSH-treated rats (***p < 0.001). Secondary damage and motor function were significantly improved in D-GSH-treated rats compared to those outcomes in L-GSH-treated rats (**p < 0.01). Moreover, D-GSH significantly decreased pro-inflammatory cytokines and glial scar via inhibition of the mitogen-activated protein kinase (MAPK) signaling pathway compared to L-GSH (***p < 0.001). In primary cultured macrophages, we found that D-GSH undergoes more intracellular interaction with activated macrophages than L-GSH (***p < 0.001). These findings reveal a potential new regenerative function of chiral GSH in SCI and suggest that chiral GSH has therapeutic potential as a treatment of other diseases. Copy rights belong to original authors. Visit the link for more info

Polymer chemistry has been one of the main disruptive forces in the last few decades, having a profound impact on materials used in all applications, enabling new technologies and profoundly impacting everyone’s life. Polymers are at the core of modern material science and despite having generated some concerning environmental challenges, it’s hard to imagine a future without them. Dr. Leibfarth is one of the most creative minds in polymer chemistry today and he is leading some incredible innovation in the way these materials are made and applied. He shares a fascinating story of elite collegiate American football, science, inspiration and creativity, as well as where different disciplines converge and provide the disruptive force to change paradigms. Paolo and Frank discuss stereo-controlled polymerization, novel functionalization, exploration of structure-function relationships, as well as Frank's personal and professional growth.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.08.16.252718v1?rss=1 Authors: Dubovski, N., Ben Shoshan-Galeczki, Y., Malach, E., Niv, M. Y. Abstract: Chirality plays a key role in biomolecular recognition. Typically, a change in chirality will dramatically affect ligand receptor binding. However, both D glucose and its enantiomer L glucose elicit sweet taste in humans. We show that L and D glucose are perceived as similarly sweet by humans, and that in cell-based functional assays, both enantiomers activate the human sweet taste receptor TAS1R2/TAS1R3. We hypothesize that both L and D glucose occupy the orthosteric binding site in the VFT domain of TAS1R2. Using induced fit docking to a homology model of this domain, we identify two subpockets in this binding site. The model suggests that glucose molecules can bind in either of these subpockets, which overlap with the predicted positions of monosaccharide units of sucrose. One subpocket is close to the hinge between the two lobes, and overlaps with aspartame and neotame site, the second subpocket overlaps with that described for sweetness enhancers. These findings suggest a framework for rational design of sweeteners combinations. Copy rights belong to original authors. Visit the link for more info

Chirality is a particularly important concept in biology, because cells are mostly composed of chiral molecules. Small chiral molecules such as amino acids and sugars (figure 1, top) are the building blocks of larger molecules, such as proteins and nucleic acids, which are also chiral. Cited Article-https://pubs.acs.org/doi/10.1021/ja0686155 One enantiomer of a chiral drug may be a medicine for particular disease whereas; another enantiomer of the molecule may be not only inactive but can also be toxic. Hence Chirality plays an essential role in drugs. Synthesising compound as single enantiomer is crucial in the design and synthesis of drugs Externally, the human body can be mirrored and it looks identical on the outside, this is what it means to be achiral.However, internally, the human body is chiral, meaning it is different when mirrored How will my skin actually benefit though? You will have healthier, plumper, more hydrated, younger-looking and problem-free skin because at the right level in your skin the right ingredients will be able to provide: increased antioxidant protection an increased rate of cellular renewal an increase in collagen and elastin an increase in cell function and skin efficiency a reduction in free radical formation chemist Arnaldo Piutti discovered D ‐asparagine and found that it tasted intensely sweet, in contrast to the known L ‐asparagine which had no taste. This was the discovery of stereoselectivity at biological receptors. As a result of advances in stereoselective synthesis and enantioselective chromatography during the last decades of the 20th century, in the 1990s the importance of molecular chirality in drug action and disposition began to receive serious attention from drug‐regulatory authorities and the pharmaceutical industry, the overall result of which has been the near‐complete disappearance of racemic drugs as newly introduced pharmaceuticals. https://pdfs.semanticscholar.org/828e/5bbdb56637326803083b6d72e6d2bc2be49a.pdf https://pdfs.semanticscholar.org/828e/5bbdb56637326803083b6d72e6d2bc2be49a.pdf https://bhsales.myctfo.com/ HTTPS://BHSALES.VPWEB.COM --- Send in a voice message: https://anchor.fm/bhsales/message Support this podcast: https://anchor.fm/bhsales/support

This week we discuss very loud bangs back in '69, the EU/ESA space projects with Brexit headaches, why life became right-handed and the chances of life on a Trappist-1 exoplanet just got more likely, no wait.. less likely? Space Song playlist on Spotify bit.ly/spacesongs If you enjoy the show please go over to www.Patreon.com/Interplanetary and become a Patron or even a producer of the show. If you enjoy why not join the BIS at www.bis-space.com the oldest space advocacy organisation in the world. Subscribe on iTunes itunes.apple.com/podcast/id1097505801 Subscribe on Stitcher www.stitcher.com/podcast/interplanetary-podcast Hosts: Matt Russell and Jamie Franklin Music: Matt Russell / Iam7 Additional Narration: George Russell www.interplanetary.org.uk @interplanetypod

This episode of About Beverages is going to take on a decidedly local flavor. The word “flavor” is doing double duty as it is referring not only to being local, but that we are also highly anticipating the actual flavor of the beverage. We are excited to try a collaboration beer from two of the best breweries in southern Arizona. While we can’t take credit for this collaboration beer actually happening, we do feel that sometime in the last year we mused about the possibility of these two local breweries getting together to create something amazing. The beverage that we will be trying on this show is the Chirality IPA, a collaboration beer from Pueblo Vida and Dragoon. The goal was to take Dragoon’s IPA and add to it the hazy twist that Pueblo Vida is so famous for. What did we think? What do you think? Let us know in the comments below or join us live on Thursday nights to give us your feedback while we are live streaming on Twitch.

This week, Dr. Shireen Adenwalla shows that condensed matter physics is brimming not only with technological promise but also with strange and beautiful phenomena. Shireen introduces Jocelyn and Bradley to superconductivity, superfluidity, and other superlatives of condensed matter physics, and she tells us how she created the website Funsize Physics to bring this cutting-edge research to a broad audience. With a little help from Samuel L. Jackson (or is it Samuel R. Jackson?), the friends discuss Shireen’s current research on chiral molecules. Finally, with her trademark wit and wisdom, Shireen offers advice for young people, and especially young women, who are embarking on careers in science. Links:NCMN: https://ncmn.unl.edu/faculty/adenwallaFunsize Physics:https://funsizephysics.com/https://www.aps.org/units/foep/newsletters/september2019/spotlight.cfmhttps://news.unl.edu/newsrooms/today/article/nebraska-led-website-shows-wonders-of-funsize-physics/https://journalstar.com/news/local/education/unl-website-puts-the-fun-in-physics/article_6f0123a6-484d-5d9d-8e3c-db232cd21b63.html Thalidomide chirality:https://www.sciencedaily.com/releases/2016/02/160208124237.htmhttps://www.youtube.com/watch?v=mrTHfBCduRAFirst Transistor: https://www.edn.com/1st-successful-test-of-the-transistor-december-16-1947/Contact Science! With Friends (especially if you’re a scientist interested in a lively conversation about your science and science story) at Gmail or Twitter!• Gmail: sciwithfriends@gmail.com• Twitter @SciWithFriends• Facebook: Science With FriendsScience! With Friends Podcast is created and hosted by Jocelyn Bosley (@SciTalker) and Bradley Nordell (@bradleynordell) and Produced by the Basement Creators Network. You can find them at https://www.basementcreators.network/Sound Editing by Vince Ruhl

DWM presents The Hidden People, episode 17 "Chirality" Written by Chris Burnside Directed by Chris and Megan Burnside   It's Mackenna's birthday. And when the Fetch answers Mackenna's phone, it prompts her to remember her last birthday...in Arcadia.   If you enjoy The Hidden People, please join us at patreon.com/hiddenpeoplepodcast to support the show and get a ton of insider bonuses. Then take a moment to share your love for The Hidden People on whatever social media you prefer. All of this helps spread the word and keep the show going.   Check out hiddenpeoplepodcast.com for more info on the show.   Connect with us: Facebook: https://www.facebook.com/hiddenpeoplepodcast/ Twitter: @dwmpresents Instagram: dwmpresents   The Hidden People is a work of fiction. Any resemblance to real persons, places, and/or events is purely coincidental.   Copyright 2019 Dayton Writers Movement ltd. All rights reserved.

Neil deGrasse Tyson, author and inventor extraordinaire Adam Savage, and comic co-host Chuck Nice answer fan-submitted questions about MythBusters, the creative process, the future of engineering, movies, and much more! NOTE: StarTalk All-Access subscribers can watch or listen to this entire episode commercial-free here: https://www.startalkradio.net/all-access/making-stuff-with-adam-savage/ Photo Credit: StarTalk©

Aaron Fried returns for a second conversation about anatomical specimens, this time discussing illustrations based on executed Nazi prisoners. Plus updates on epigenetics, handedness in cells, HAPS sponsorship, making course content accessible to all students. Oh, and your homework. 00:40 | Listen up: feedback on accommodating hearing impairment 05:06 | HAPS is now a sponsor of this podcast! 06:36 | Update in epigenetics 10:07 | Handedness in cells 13:45 | Featured: The Nazi Anatomists (a chat with Aaron Fried)   If you cannot see or activate the audio player click here. Questions & Feedback: 1-833-LION-DEN (1-833-546-6336) Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram!   I never teach the same course twice. (Elie Wiesel)   1 | Listen up! 4.5 minutes Feedback from listener Ron Parente leads to a discussion of how accommodating for hearing impairments and other challenges actually help all learners—not just those needing accommodation. Have questions, comments, stories, or ideas related to accommodating student needs? Pass them along for a future episode focused on this topic. Don't forget your homework assignment: share this podcast with ONE other A&P colleague before the next episode arrives. Yes, I do accept late homework.   2 | HAPS is now a sponsor of this podcast 1.5 minutes The Human Anatomy & Physiology Society (HAPS) is now a sponsor of this podcast. You can help appreciate their support by clicking the link below and checking out the many resources and benefits found there. Anatomy & Physiology Society (the HAPS website, where you can explore resources and check out the membership options) @HumanAandPhysSoc (follow the HAPS Twitter feed)     3 | Update in epigenetics 3.5 minutes Epigenetic inheritance is known to involve various factors impacting DNA, such as methylation. We are now seeing roles for RNAs, including the long RNAs from sperm than enable epigenetic inheritance via the male parent. Studies raise questions over how epigenetic information is inherited (short, plain English summary) Alterations in sperm long RNA contribute to the epigenetic inheritance of the effects of postnatal trauma (Research journal article)    4 | Handedness in cells 3 minutes Chirality is "handedness" or the characteristics of having mirror-image versions. You may be familiar with this phenomenon in cells, but did you know it also occurs in cells? New research suggests that a change in handedness in diabetes mellitus may explain how blood vessels get leaky. Flipped Cells Cause Blood Vessels To Leak in Diabetes and Other Diseases (press release explaining the new research) Cell chirality regulates intercellular junctions and endothelial permeability (Research journal article)   5 | The Nazi Anatomists—A Conversation with Aaron Fried 21 minutes Aaron Fried, A&P faculty at Mohawk Valley Community College and national speaker on human body donation and anatomists in Nazi Germany, joins Kevin for a lively discussion of the value of "the silent teacher"—the human body donor—in teaching human structure. In this second of two chats, Aaron discusses illustrations produced using executed prisoners in Nazi Germany and what this means for today's A&P teacher. Episode 29 (our first conversation, which which touched on the ethics of using human body donors) Who Was Eduard Pernkopf? (Aaron Fried's video explains some of the history around Eduard Pernkopf and defines the Pernkopf controversy.) https://www.mvccanatomy.org/ (Aaron Fried's website) professoranatomeme (Aaron Fried's Instagram) The Immortal Life of Henrietta Lacks (The A&P Professor Book Club selection by Rebecca Skloot; mentioned by Aaron Fried) History & Culture Mini Lesson (part of Kevin's course outline that explores issues of using human bodies in anatomy) Anatomy and Ethical Transgressions in National Socialism (video of a talk given by Sabine Hildebrandt at Harvard) Researchers Issue Guidelines on Handling Holocaust Remains (video with text summary; includes application of "Vienna protocols" to anatomical art, as mentioned by Aaron Fried)   If the hyperlinks here are not active, go to TAPPradio.org to find the episode page. More details at the episode page. Transcript available at the script page. Listen to any episode on your Alexa device. Join The A&P Professor social network: Blog Twitter @theAPprofessor Facebook theAPprofessor Instagram theAPprofessor YouTube Amazon referrals help defray podcasting expenses. Transcript and captions for this episode are supported by the American Association of Anatomists. The Human Anatomy & Physiology Society also provides support for this podcast.(Clicking on sponsor links helps let them know you appreciate their support of this podcast!)  

Host Kevin Patton previews the content of The Nazi Anatomists, featuring another chat with Aaron Fried. There's more...including a small bit of bonus content to make the full episode more meaningful to listeners...including a recommendation from The A&P Professor Book Club.   If you cannot see or activate the audio player click here. Questions & Feedback: 1-833-LION-DEN (1-833-546-6336) Follow The A&P Professor on Twitter, Facebook, Blogger, Nuzzel, Tumblr, or Instagram!   This preview is an experiment. Do you like having a preview? Do you like the "bonus content" that goes beyond a simple preview? Or has it ruined your life? Let me know: 1·833·LION·DEN (1·833·546·6336) podcast@theAPprofessor.org    There's upcoming news about this podcast's relationship with the Human Anatomy & Physiology Society (HAPS)!   The A&P Professor Book Club has a new recommendation in this preview: The Silent Teacher: The Gift of Body Donation by Dr. Claire Smith (paperback available in UK)   If the hyperlinks here are not active, go to TAPPradio.org to find the episode page. More details at the episode page. Transcript available at the script page. Listen to any episode on your Alexa device. Join The A&P Professor social network: Blog Twitter @theAPprofessor Facebook theAPprofessor Instagram theAPprofessor YouTube   Amazon referrals help defray podcasting expenses.   Transcript and captions for this episode are supported by the American Association of Anatomists.     The Human Anatomy & Physiology Society also provides support for this podcast. (Clicking on sponsor links helps let them know you appreciate their support of this podcast!)    

How can Chemistry take inspiration from nature to create cleaner and more efficient ways of producing and using Hydrogen as a source of clean energy? Professor Kylie Vincent explains how bacteria may hold the key to harnessing Hydrogen as a clean energy source: Chemists are looking to understand how bacteria make use of Hydrogen as efficiently as they do using common metals. The hope is that we may be able to learn from them to inspire our own fuel cells. Currently, we have to use really expensive metals, like Platinum: something you might rather use to create jewellery, rather than the innards of a car. And what we can learn from nature doesn't just stop there. Bacteria are also very good at making specific molecules, e.g., those that might be of interest as drugs. And they do it better than we can! Kylie also describes work in this area to make use of bacterial cell 'machinery' to carry out specific chemical reactions.

In this video, students are introduced to the concept of chiral molecules and the relationship between molecular structure and function.

Oxford Sparks explore what chirality is. What links drugs, shells, springs and vines? Chirality, when mirror images of things don't look the same, is explored and we learn what maths can tell us about it - from designing drugs to the very meaning of life.

00:00:00 - Charlie and Ryan are joined by Chad Jones, the host of the newest show in the Brachiolope Media Network, The Collapsed Wavefunction! Our first topic is about modifying the surface of the planet to run experiments about sand dune formations. It's possibly the most excited Charlie has been on the mic in a long time. Plus, Chad informs us about hydrophobic sand, which sounds dangerously fun.   00:18:55 - The drinks too, must flow. Charlie has the very proprietary Rogue Chocolate Stout. Chad, clearly worried he won't be invited back anytime soon, doubles down with a Jone's Soda and a Flying Cauldron Butterscotch Beer. Ryan begins his local beer journal with the totally expected Cerveza Panama.   oo:24:55 - Trailer Trash Talk goes tactical (whatever that means) with the preview for the all-new but not really new at all remake of the 80's 'classic' Robocop.   00:36:09 - Robots may not sweat, but people do. People also need drinking water. Well now some nerds have made a machine to turn human sweat into drinkable water. Refreshing, or just gross?   01:01:09 - PaleoPOWs are a lot drinking your own sweat; self-involved and perplexing to others. Charlie thanks Kris T. for a nice e-mail and hefty donation. Thanks, Kris! Ryan fields a correction about gender vs. sex from Episode 183 sent in by Liam T. (not from England). And Chad thankfully knows the answers to Liz C.'s questions of chirality and sugar substitutes. Be sure to bug Chad on Twitter and tell him about the chemical topics you want to hear on his podcast!   Thanks for listening and be sure to check out the Brachiolope Media Network for more great science podcasts!   Music for this week's show: Dune Buggy - Presidents of the United States of America Panama - Van Halen I Am Not A Robot - Marina and the Diamonds Don't Drink the Water - Dave Matthews Band  

Zumer, S (University of Ljubljana) Monday 24 June 2013, 14:45-15:30

We look at the work of Stephanie Getty at NASA Goddard Space Flight Center

In this episode, we examine a useful method determinig R/S conifgurations, travel to our virtual whiteboard and see an animation to help you visualize how to rotate chiral carbon atoms.

http://webs.anokaramsey.edu/aspaas/2061/video/9.2%20Chirality.m4v Sat, 06 Nov 2010 04:46:09 -0500 Higher Education

Chirality; enantiomers; assigning configuration; diastereomers; meso compounds; racemic mixtures; stereochemistry of reactions

The exciting discovery in 1985 of an unknown form of carbon, the building blocks of today's nano world. Introducing the Electron and Scanning Tunnelling Microscopes in Cambridge.

Transcript -- The exciting discovery in 1985 of an unknown form of carbon, the building blocks of today's nano world. Introducing the Electron and Scanning Tunnelling Microscopes in Cambridge.

Transcript -- The exciting discovery in 1985 of an unknown form of carbon, the building blocks of today's nano world. Introducing the Electron and Scanning Tunnelling Microscopes in Cambridge.

The exciting discovery in 1985 of an unknown form of carbon, the building blocks of today's nano world. Introducing the Electron and Scanning Tunnelling Microscopes in Cambridge.

In the first part, the use of chirality transfer in acyclic allylic systems was assessed for an intra- and an intermolecular reaction. The thermal [2,3] sigmatropic rearrangement of acyclic allylic phosphinites proved to be highly enantioselective, even at 110 °C and led to enantiomerically pure allylic phosphine oxides. The substitution pattern of the substrate and the reaction conditions were fully optimized.The chirality transfer concept was also used intermolecularly in asymmetric allylic substitution reactions. This allowed to build up enantiomerically pure quaternary centers. The product were then reacted to obtain enantionerically pure tertiary alcohols, desymmetrized 1,3 diols and aldol compounds. In a second part, it was found that Heck reaction leading to neopentylic palladium species underwent, in the absence of nucleophile, a C-H activation reaction, leading to spiro cyclopropyl compounds.