Podcasts about developmental origins

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Best podcasts about developmental origins

Latest podcast episodes about developmental origins

Conversations in Fetal Medicine
In conversation with Professor Lucilla Poston - recorded live at RCOG Annual Academic Meeting! Bonus episode

Conversations in Fetal Medicine

Play Episode Play 28 sec Highlight Listen Later Aug 24, 2024 52:59


Send us a Text Message.Welcome to a special bonus episode! Recorded live at the RCOG Annual Academic Meeting in January 2024, organised by the Blair Bell Research Society. Join us in conversation with Professor Lucilla Poston, co-hosted with the fabulous Dr Neil Ryan (a clinical academic and subspecialty trainee in gynae-oncology). This is also a chance to celebrate the RCOG Annual Academic Meeting and learn a bit more about the Blair Bell Research Society. With thanks to the RCOG and BBRS for permission to share the recording.  Professor Poston's bio:https://www.kcl.ac.uk/people/lucilla-postonProfessor Lucilla Poston CBE is a Professor of Maternal & Fetal Health in the School of Life Course & Population Sciences. Her research spans maternal nutrition, obesity and gestational diabetes with a focus on the short as well as longer term consequences for the health of mother and the child. Approaches include studies in mother -child cohorts and development of pragmatic interventions in pregnancy to improve pregnancy outcome and child health. Her team also interrogate the early life origins of disease through maternal and child electronic health record data linkages.Professor Poston is President of the International Society for Developmental Origins of Health and Disease, an Honorary Fellow of the Royal College of Obstetricians and Gynaecologists (FRCOG) and was elected Fellow of the Academy of Medical Sciences in 2009. She was appointed NIHR Senior Investigator, Emeritus in 2017, having succeeded twice in open competition. In 2017, Lucilla was awarded a CBE for services to Women's Health. In 2024 Lucilla was listed by Research.com as being one of the top 1000 female scientists in the world, according to the H Index.Previously Professor Poston was the Tommy's Chair of Maternal & Fetal Health and the Director of the Tommy's Maternal & Fetal Research Unit based at St Thomas' Hospital, and the Head of the School of Life Course & Population Sciences.RCOG Annual Academic Meeting info:The RCOG Annual Academic meeting ‘Save the date' and call for abstracts has just been announced! 6-7 Feb 2025https://rcog.eventsair.com/annual-academic-meeting-feb-2025Dr Neil Ryan's bio:https://www.ed.ac.uk/profile/neilryanNeil is the RCOG Subspecialty Trainee in Gynaecology Oncology at the Royal Infirmary of Edinburgh and a CSO/NES Clinical Lecturer at the University of Edinburgh.He was awarded a personal MRC fellowship to undertake a PhD at the University of Manchester (UoM) which he completed in 2020. His thesis was supervised by Professors Crosbie and Evans.His PhD led to a change in NICE guidelines relating to the testing of womb cancer along with numerous publications, presentations, invited lectures and awards.Neil's work was recognised by a President's Doctorial Scholarship and awarded the UoM's highest postgraduate award: The President's Medal. Neil was recently awarded the William Blair Bell Lecture by the RCOG.British Gynaecological Cancer Society (BGCS) podcast info:https://www.bgcs.org.uk/professionals/new-podcast-series/Podcast information:We have not included any patient identifiable information, and this podcast is intended for professional education rather than patient information (although welcome anyone interested in the field to listen). Please get in touch with feedback or suggestions for future guests or topics: conversationsinfetalmed@gmail.com, or via Twitter (X) or Instagram via @fetalmedcast.Music by Crowander ('Acoustic

Sausage of Science
SoS 210: Dr. Chris Kuzawa on the Developmental Origins of Health and Disease (DOHaD)

Sausage of Science

Play Episode Listen Later Mar 11, 2024 48:13


Cara and guest co-host Cristina sit down with Dr. Chris Kuzawa, the John D. MacArthur Professor & Faculty Fellow at the Institute for Policy Research at Northwestern University. He uses principles from anthropology and evolutionary biology to gain insights into the biological and health impacts of human developmental plasticity. His primary field research is conducted in Cebu, the Philippines, where he and his colleagues work with a large birth cohort study that enrolled more than 3,000 pregnant women in 1983 and has since followed their offspring into adulthood (now 30 years old). They use the nearly 3 decades of data available for each study participant, and recruitment of generation 3 (the grand offspring of the original mothers), to gain a better understanding of the long-term and intergenerational impacts of early life environments on adult biology, life history, reproduction, and health. A theme of much of his work is the application of principles of developmental plasticity and evolutionary biology to issues of health. ------------------------------ Contact Chris: kuzawa@northwestern.edu Website: https://sites.northwestern.edu/kuzawa/; Twitter:@ChrisKuzawa ------------------------------ Contact the Sausage of Science Podcast and Human Biology Association: Facebook: facebook.com/groups/humanbiologyassociation/, Website: humbio.org, Twitter: @HumBioAssoc Cara Ocobock, HBA Public Relations Committee Chair, Cara Ocobock, Co-Host, Website: sites.nd.edu/cara-ocobock/, Email:cocobock@nd.edu, Twitter: @CaraOcobock Cristina Gildee, HBA Junior Fellow, SoS producer Website: cristinagildee.org, E-mail: cgildee@uw.edu, Twitter: @CristinaGildee

Le Labo des savoirs
Empreinte nutritionnelle, tout est foetus !

Le Labo des savoirs

Play Episode Listen Later Jan 31, 2024 60:00


Notre vie commence des mois avant notre arrivée au monde, alors que nous sommes encore au chaud dans le ventre maternel. Les dernières recherches suggèrent que cette période de 9 mois est loin d'être une bulle isolée de l'extérieur, au contraire : elle aurait des influences sur l'ensemble de notre vie ! Notamment quand on parle de l'alimentation… On appelle cela l'empreinte nutritionnelle et pour en parler dans cette émission, nous recevons : Patricia PARNET, neurobiologiste qui a dirigé jusqu'en 2023 l'unité de recherche de Physiopathologie des Adaptations Nutritionnelles (ou PhAN) de Nantes Université, localisée au CHU de Nantes. Dans cette émission, nous entendrons également la chronique de Lénaïg, sur les dangers de l'exposition du fœtus aux micro plastiques, et comment s'en prémunir. Lila nous parleras enfin de l'évolution du régime alimentaire de bébé à travers l'Histoire. Cette émission a été préparée et réalisée par Sophie Podevin. Ressources : le site des 1 000 premiers jours du gouvernement le site de l'unité PhAN de Nantes Université article sur la DOHaD, ou Developmental Origins of Health and Disease (l'origine du développement de la santé et des maladies)

The EMJ Podcast: Insights For Healthcare Professionals
Episode 186: Type 2 Diabetes: Developmental Origins of Health and Disease

The EMJ Podcast: Insights For Healthcare Professionals

Play Episode Listen Later Jan 25, 2024 38:05


In this week's episode, Jonathan is joined by Aleksander Lühr Hansen, Steno Diabetes Center, Copenhagen, Denmark; and Aarhus University Hospital, Denmark. The pair discuss low birthweight and fetal programming, in the context of the associated increased risk of developing conditions like Type 2 diabetes.   Use the following timestamps to navigate the content in this episode: (00:00)-Introduction  (01:50)-Alexander's route in medicine and diabetes  (03:50)-Research on low birthweight  (05:44)-Fetal programming  (10:11)-The ‘thrifty phenotype'  (12:55)-Low birthweight and Type 2 diabetes development  (19:45)-Alexander's experiences in Tanzania  (24.06)-Adverse pregnancy outcomes and incident heart failure  (27.19)-The translational Type 2 diabetes research group  (30:00)-Projects for the future  (33.01)-Three wishes 

Biopedia
70- The Microbiome and Microbiota

Biopedia

Play Episode Listen Later Dec 24, 2023 11:46


Most people will have come across this term before, but what does it actually mean? Today, we'll be dissecting the terms microbiome and microbiota and looking at what can impact them. Sources for this episode: Amon, P. and Sanderson, I. (2017), What is the microbiome? Archives of Disease in Childhood- Education and Practice 102-258-261. Cremon, C., Barbaro, M. R., Ventura, M. and Barbara, G. (2018), Pre- and probiotic overview. Current Opinion in Pharmacology 43: 87-92. Kim, H., Sitarik, A. R., Woodcroft, K., Johnson, C. C. and Woratti, E. (2019), Birth Mode, Breastfeeding, Pet Exposure and Antibiotic Use: Associations With the Gut Microbiome and Sensitization in Children. Current Allergy and Asthma Reports 19: 22. Mariat, D., Firmesse, O., Levenez, F., Guimarăes, V. D., Sokol, H., Doré, J., Corthier, G. and Furet, J.-P. (2009), The Firmicutes:Bacteroidetes ratio of the human microbiota changes with age. BMC Microbiology 9:123. Rautava, S. (2016), Early microbial contact, the breast milk microbiome and child health. Journal of Developmental Origins of Health and Disease 7(1): 5-14. Rees, T., Bosch, T. and Douglas, A. E. (2018), How the microbiome challenges our concept of self. PLoS Biology 16(2): e2005358. Sender, R., Fuchs, S. and Milo, R. (2016), Revised estimates for the number of human and bacteria cells in the body. PLoS Biology 14(8): e1002533. Tojo, R., Suárez, A., Clemente, M. G., de los Reyes-Gavilán, C. G., Margolles, A., Gueimonde, M. and Ruas-Madiedo, P. (2014), Intestinal microbiota in health and disease: Role of bifidobacteria in gut homeostasis. World Journal of Gastroenterology 20(41): 15163-15176. Vongsa, R., Hoffman, D., Shepard, K. and Koenig, D. (2019), Comparative study of vulva and abdominal skin microbiota of healthy females with high and average BMI. BMC Microbiology 19:16. Author unknown, NHS (date unknown), Irritable bowel syndrome (IBS) (online) (Accessed 16/11/2023).

The Disrupted Workforce
The Science Of Resilience, Failure, And Human Connection | Dr. Dani Dumitriu

The Disrupted Workforce

Play Episode Listen Later Nov 28, 2023 46:01


DETAILS | What is the science of human connection that defines the magnetism between us? Why do some people connect while others don't? How can we become more resilient and embrace failure? Join us in this enlightening episode of The Disrupted Workforce, where we delve into the fascinating world of resilience, failure, and human connection with our distinguished guest, Dr. Dani Dumitriu. A renowned pediatrician, neuroscientist, and pediatric environmental health scientist, Dr. Dumitriu shares her groundbreaking research on the neural circuits of stress resilience. You will be amazed by her discoveries surrounding the science behind human magnetism, the nature of social bonds, and the importance of early life experiences in shaping resilience. Her work is more than academic; it's a journey to decode the essence of human connections and the invisible forces that bind us together. This episode is a must-listen for anyone interested in the interplay between mental health, resilience, biology, and the vital role of human connections in our lives and at work. GUEST | Step into the world of Dr. Dani Dumitriu, a trailblazing figure at the intersection of neuroscience, pediatrics, and pediatric environmental health science. With an impressive background combining medical practice and scientific research, Dr. Dumitriu stands as a luminary in understanding the intricacies of human resilience and connection. At the prestigious Columbia University Medical Center, Dr. Dumitriu leads innovative research in her Developmental Origins of Resilience (DOOR) lab. Her groundbreaking work sheds light on the neural circuits underpinning stress resilience, not just in humans but across species, offering profound insights into our biological and psychological makeup. Dr. Dumitriu is committed to unraveling the mysteries of early life experiences and their lasting impact on mental and physical health. Her insights into human magnetism, the invisible threads that connect individuals, and the nurturing of resilience from a young age make her a voice of wisdom and powerful innovation in the field. OVERVIEW | Are you ready to ADAPT and REINVENT YOURSELF for the most disrupted and digital workforce in history? What would it feel like to belong and not get stuck? It is estimated over 1 billion people will need reskilling by 2030, and more than 300 million jobs will be impacted by AI  — work, identity, and what it means to be human are rapidly changing. Join hosts Nate Thompson and Alex Schwartz and the TOP VOICES in the Future of Work to uncover how to meet this dynamic new reality driven by AI, hybrid work, societal shifts, and our increasingly digital world. Discover why a Future of Work Mindset is your key to prepare, navigate, and thrive! We are grateful you are here, and welcome to the TDW Tribe! www.thedisruptedworkforce.com

Undisciplinary
Reflections: The Impact of Preconception Health and Societal Pressures on Reproductive Outcomes

Undisciplinary

Play Episode Listen Later Nov 14, 2023 14:14 Transcription Available


**The below is AI generated**What would it feel like to constantly plan for something as life-changing as pregnancy, but feel ill-equipped to prepare for it? What if we told you that your health decisions pre-conception could impact not just your child, but generations to come? In today's episode, we're diving headfirst into the complexities of pregnancy planning and the repercussions of insufficient preparation. We're dissecting a recent study that found a shocking disparity between the women who plan their pregnancies and those who take active steps to prepare for them. The concept of 'Developmental Origins of Health and Disease' and its unique focus on women forms a critical part of our discussion. We particularly emphasize on the crucial yet often overlooked role of paternal health and the need for interdisciplinary collaborations to enhance overall reproductive health.As the conversation proceeds, we shift focus to explore the unique health challenges faced by overweight women preparing for pregnancy. It's no secret that societal discourse around women's bodies is riddled with negativity, but how does this impact a woman's ability to prepare for pregnancy? How do these biases and pressures complicate weight management during pregnancy? We delve into these dilemmas, shedding light on issues often swept under the rug. This episode is an earnest attempt to delve deeper into the societal pressures, health dilemmas, and the critical need for empathic and comprehensive healthcare for all women, regardless of their body size. So, brace yourself as we navigate this complex terrain in our latest episode.Here is the article Chris refers to:  Situating the Father: Strengthening Interdisciplinary Collaborations between Sociology, History and the Emerging POHaD ParadigmUndisciplinary - a podcast that talks across the boundaries of history, ethics, and the politics of health. Follow us on Twitter @undisciplinary_ or email questions for "mailbag episodes" undisciplinarypod@gmail.com

Researchers Under the Scope
Dr. Wendie Marks: Researching Complex Connections Between Stress, Nutrition & Health

Researchers Under the Scope

Play Episode Listen Later Oct 30, 2023 21:26


By the end of her Grade Eight year in Saskatoon, Wendie Marks was sure about one thing: she knew she wanted to study health and the way early-life development affected the human body.   “I spent a lot of time in the library reading books,” Marks said. “I was always kind of the nerdy type.”   Marks enrolled at the University of Saskatchewan and thrived, earning her PhD in psychology. Her interests evolved towards behavioural neuroscience, focusing on the mechanisms behind behaviour, stress, and their effects on mental and physical health.   “I wanted to make new knowledge. I wanted to be on the cutting edge of finding new pathways that might be involved in anxiety, or depression,” she said.   Under the direction of Dr. Lisa Kalanchuk, Marks looked at stress and depression, during her graduate studies at the University of Saskatchewan. From there, her post-doctoral research veered into epilepsy models at the University of Calgary. Still, Marks' passion for understanding stress and its intergenerational effects never wavered.   When she returned to the University of Saskatchewan last year as an assistant professor in the Department of Pediatrics, Marks steered her research toward investigating stress's effects on health and chronic disease.   This summer, she was appointed as a Tier 2 Canada Research Chair in Developmental Origins of Health and Disease in Indigenous People. Over the next five years, she plans to study the way life experiences, particularly stress and nutrition during pregnancy and early years, can have long-term effects on an individual's health and well-being.    This research isn't just academic for Dr. Marks; it's deeply personal.    Marks is a member of the Asnishinabe of Wauzhushk Onigum First Nation, near Lake of the Woods, Ontario, but she was born and raised in Saskatoon. Her mother and her siblings survived both residential school and the “60s Scoop”.   “The whole family was split up. There are aunts and uncles I've never even met,” said Marks.  "I've seen within my family firsthand the effects that those stressors have played on people, and the effects those things can have on families.”   Today, Marks credits her academic and research career to her mother's unwavering support, encouragement and resilience.    "She's one of the strongest people I know,” said Marks.   In this episode, Marks explained she'll study stress in two different ways. First, she plans to use a multi-generational rat model to study the consequences of early-life stress by separating mothers from their pups. She'll also model malnutrition by reducing the mother's protein intake.    Her goal is to measure each set of stressors separately, then assess whether they have a deeper effect combined.    “Being hungry or exposed to stress when you're younger, chronically, it's possible that it can rewire your stress circuitry,” said Marks, who noted that is the case in numerous animal models.    Her team will investigate how these factors can lead to physiological and cognitive changes, particularly in obesity and brain circuitry.    In the second stage of her research, Marks will observe health conditions in those rats' descendants, and propose potential treatments.   ‘There's a lot of compelling evidence to suggest that stress and the gut microbiome are linked together and affect our health later on in life,” Marks said.    Ultimately, Marks hopes to apply the findings from animal studies to real-world situations within Indigenous communities, and help them come up with preventive strategies.   She hopes to bridge the gap between knowledge and action, ultimately improving the health and well-being of Indigenous communities for generations to come.   "Knowledge itself is powerful," Marks said. “The hope is that with this research we begin to find some of the answers and some of the solutions to decolonize Indigenous communities.”   Her work is a testament to resilience, hope, and the profound impact of science in healing intergenerational trauma.   “It's a significant motivator for my research,” Marks said. “What can I contribute to try to make our world a better place?”This summer, she was appointed as a Tier 2 Canada Research Chair in Developmental Origins of Health and Disease in Indigenous People. Over the next five years, she plans to study the way life experiences, particularly stress and nutrition during pregnancy and early years, can have long-term effects on an individual's health and well-being.    This research isn't just academic for Dr. Marks; it's deeply personal.    Marks is a member of the Asnishinabe of Wauzhushk Onigum First Nation, near Lake of the Woods, Ontario, but she was born and raised in Saskatoon. Her mother and her siblings survived both residential school and the “60s Scoop”.   “The whole family was split up. There are aunts and uncles I've never even met,” said Marks.  "I've seen within my family firsthand the effects that those stressors have played on people, and the effects those things can have on families.”   Today, Marks credits her academic and research career to her mother's unwavering support, encouragement and resilience.    "She's one of the strongest people I know,” said Marks.   In this episode, Marks explained she'll study stress in two different ways. First, she plans to use a multi-generational rat model to study the consequences of early-life stress by separating mothers from their pups. She'll also model malnutrition by reducing the mother's protein intake.    Her goal is to measure each set of stressors separately, then assess whether they have a deeper effect combined.    “Being hungry or exposed to stress when you're younger, chronically, it's possible that it can rewire your stress circuitry,” said Marks, who noted that is the case in numerous animal models.    Her team will investigate how these factors can lead to physiological and cognitive changes, particularly in obesity and brain circuitry.    In the second stage of her research, Marks will observe health conditions in those rats' descendants, and propose potential treatments.   ‘There's a lot of compelling evidence to suggest that stress and the gut microbiome are linked together and affect our health later on in life,” Marks said.    Ultimately, Marks hopes to apply the findings from animal studies to real-world situations within Indigenous communities, and help them come up with preventive strategies.   She hopes to bridge the gap between knowledge and action, ultimately improving the health and well-being of Indigenous communities for generations to come.   "Knowledge itself is powerful," Marks said. “The hope is that with this research we begin to find some of the answers and some of the solutions to decolonize Indigenous communities.”   Her work is a testament to resilience, hope, and the profound impact of science in healing intergenerational trauma.   “It's a significant motivator for my research,” Marks said. “What can I contribute to try to make our world a better place?”

POP: Perspectives on Public Health
Air Pollution and Pregnancy with Carrie Breton, ScD and Zhongzheng Jason Niu, PhD

POP: Perspectives on Public Health

Play Episode Listen Later May 24, 2023 6:35


Carrie Breton, ScD is a professor of population and public health sciences and co-director of the Maternal And Developmental Risks from Environmental and Social Stressors (MADRES) Center for Environmental Health Disparities. Breton is interested in understanding how prenatal environmental exposures and stressors affect epigenetic pathways and maternal and child health outcomes.Zhongzheng Niu, PhD is a postdoctoral scholar in the Department of Population and Public Health Sciences. He has a broad interest in understanding early life environmental risk factors and biological mechanisms for the Developmental Origins of Health and Disease (DOHaD) theory, with a particular focus on cardiovascular diseases (CVD) and aging-related biomarkers.Read the story at USC NewsVisit the MADRES Center online at madres.usc.eduLearn more about this episode and others at pphs.usc.edu/podcastStay in the loop - subscribe to the Preventive Dose newsletter for monthly news straight to your inbox.Follow us on social - find us at @uscpphs Instagram TikTok Facebook LinkedIn Twitter YouTube

Women's Wellness Psychiatry
Why We Must Treat Anxiety & Stress in Pregnancy

Women's Wellness Psychiatry

Play Episode Listen Later Mar 3, 2023 18:38


I define concepts like anxiety, worry, and stress, and review the potential negative consequences on child development if mothers experience these symptoms during pregnancy, with the goal of encouraging treatment and support. To learn more about me and my reproductive psychiatry clinic helping patients across California, please visit - AnnaGlezerMD.comHelpful resources:2021 Review of Stress in Pregnancy: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8824223/2020 Review of Stress in Pregnancy that describes the Developmental Origins of Disease Hypothesis: https://pubmed.ncbi.nlm.nih.gov/28757456/2021 Review of Resilience and Stress in Pregnancy: https://pubmed.ncbi.nlm.nih.gov/34434079/2022 JAMA Article of Impacts on Toddlers: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2791732

The Global Health Collective - With a Local Edge
5.2 A Chat with Dr. Deborah Sloboda on Wellness, Work-Life and Early Origins Science

The Global Health Collective - With a Local Edge

Play Episode Listen Later Aug 4, 2022 27:53


Don't sweat the small stuff and focus on doing your best, even in the worst case scenario. In this episode, we are joined with positive energy from Dr. Deb Sloboda who is a researcher, professor at McMaster University, and one of the founding Co-Presidents of the Developmental Origins of Health and Disease Society of Canada. Her work involves understanding the impact of early life adversity on the mother, and the developing fetus and how fetal adaptations to adversity influence the risk of chronic disease later in life. Join us in a discussion about work-life integration, the incorporation of acts of service and fostering healthy relationships to promote well-being.

Neurosapiens
37 | Celui où on parlait de l'empathie

Neurosapiens

Play Episode Listen Later May 18, 2022 13:12


Dans l'épisode de cette semaine, nous verrons ensemble qu'est-ce réellement l'empathie. Quelles sont les origines cérébrales de l'empathie ? Nous verrons aussi les limites du fonctionnement de l'empathie : pourquoi éprouvons-nous plus d'empathie pour notre voisin plutôt que pour une personne à l'autre bout du monde ? Et enfin, ma question fétiche : mais pourquoi Homo Sapiens a développé et conservé cette capacité au fil des millénaires ?Soutenir et s'abonner à NeurosapiensProduction, animation, réalisation et illustration : Anaïs RouxInstagram : https://www.instagram.com/neurosapiens.podcast/neurosapiens.podcast@gmail.comMusique d'intro KEEP ON GOINGMusique proposée par La Musique LibreJoakim Karud - Keep On Going : https://youtu.be/lOfg0jRqaA8Joakim Karud : https://soundcloud.com/joakimkarudSOURCESZaki J, Ochsner KN. The neuroscience of empathy: progress, pitfalls and promise. Nat Neurosci. 2012 Apr 15;15(5):675-80. doi: 10.1038/nn.3085. Erratum in: Nat Neurosci. 2013 Dec;16(12):1907. Ochsner, Kevin [corrected to Ochsner, Kevin N]. PMID: 22504346.Lamm C, Batson CD, Decety J. The neural substrate of human empathy: effects of perspective-taking and cognitive appraisal. J Cogn Neurosci. 2007 Jan;19(1):42-58. doi: 10.1162/jocn.2007.19.1.42. PMID: 17214562.J. Decety et al., Neurodevelopmental changes in the circuits underlying empathy and sympathy from childhood to adulthood, in Developmental Science, publication en ligne, 2010.Warrier, V., Toro, R., Chakrabarti, B. et al. Genome-wide analyses of self-reported empathy: correlations with autism, schizophrenia, and anorexia nervosa. Transl Psychiatry 8, 35 (2018). https://doi.org/10.1038/s41398-017-0082-6Chen C, Martínez RM, Cheng Y. The Developmental Origins of the Social Brain: Empathy, Morality, and Justice. Front Psychol. 2018 Dec 14;9:2584. doi: 10.3389/fpsyg.2018.02584. PMID: 30618998; PMCID: PMC6302010.Singer T, Seymour B, O'Doherty JP, Stephan KE, Dolan RJ, Frith CD. Empathic neural responses are modulated by the perceived fairness of others. Nature. 2006 Jan 26;439(7075):466-9. doi: 10.1038/nature04271. Epub 2006 Jan 18. PMID: 16421576; PMCID: PMC2636868.Danziger N, Faillenot I, Peyron R. Can we share a pain we never felt? Neural correlates of empathy in patients with congenital insensitivity to pain. Neuron. 2009 Jan 29;61(2):203-12. doi: 10.1016/j.neuron.2008.11.023. PMID: 19186163.Morishima Y, Schunk D, Bruhin A, Ruff CC, Fehr E. Linking brain structure and activation in temporoparietal junction to explain the neurobiology of human altruism. Neuron. 2012 Jul 12;75(1):73-9. doi: 10.1016/j.neuron.2012.05.021. PMID: 22794262. Voir Acast.com/privacy pour les informations sur la vie privée et l'opt-out. Become a member at https://plus.acast.com/s/neurosapiens.

Science & Chill
Episode 31: Exercise during Pregnancy and Developmental Origins of Health and Disease with Dr. Brittany Allman

Science & Chill

Play Episode Listen Later Jun 14, 2021 81:29


In this episode of the podcast, I interview Dr. Brittany Allman. Dr. Allman is a postdoctoral researcher at the University of Arkansas for Medical Sciences, where her areas of research include the maternal programming of obesity — how a mother's health can influence the metabolic health of her offspring. She also is interested in the effect of obesity on mother and child health outcomes. Another promising area in which Dr. Allman is researching is exercise during pregnancy, and this was the main reason I wanted to interview her. We discuss the safety of exercise during pregnancy, the beneficial effects that exercise can exert throughout pregnancy on a mother's health, and some fascinating science related to how exercise can influence the health of the baby through epigenetic and other types of metabolic and fetal programming.   Links - DrBrittanyRAllman.com - Follow Dr. Allman on Twitter: @DrBrittRAllman - Follow Dr. Allman on Instagram: @DrBrittanyRAllman - List of Dr. Allman's scientific publications (Google Scholar)   Podcast links - Listen on Apple Podcasts - Listen on Spotify - Become a Patreon supporter - Make a donation to the podcast (PayPal) - Try LMNT electrolyte drink mix (FREE sample pack)

Curiosity Daily
Stress During Pregnancy Might Affect the Baby's Sex

Curiosity Daily

Play Episode Listen Later Jun 8, 2021 13:11


Learn about how stress during pregnancy can affect a newborn's sex; skipping stone physics in space; and overspending. Stress can make a pregnant person twice as likely to have a girl by Grant Currin Beres, D. (2021, April 13). Stressed-out mothers are twice as likely to give birth to a girl. Big Think; Big Think. https://bigthink.com/surprising-science/stress-pregnancy  Romero-Gonzalez, B., Puertas-Gonzalez, J. A., Gonzalez-Perez, R., Davila, M., & Peralta-Ramirez, M. I. (2021). Hair cortisol levels in pregnancy as a possible determinant of fetal sex: a longitudinal study. Journal of Developmental Origins of Health and Disease, 1–6. https://doi.org/10.1017/s2040174420001300  Scientists have shed light on the physics of skipping stones to make landing spacecraft safer by Briana Brownell Tang, J., Zhao, K., Chen, H., & Cao, D. (2021). Trajectory and attitude study of a skipping stone. Physics of Fluids, 33(4), 043316. https://doi.org/10.1063/5.0040158  Stone skipping techniques can improve reentry of space vehicles. (2021). EurekAlert! https://www.eurekalert.org/pub_releases/2021-04/aiop-sst041521.php  Advanced Aerospace Medicine On-line. (2018, April 11). FAA.gov.  https://www.faa.gov/about/office_org/headquarters_offices/avs/offices/aam/cami/library/online_libraries/aerospace_medicine/tutorial/media/III.4.1.7_Returning_from_Space.pdf  Lovell, J., Kluger, J. (1994). Apollo 13. Houghton Mifflin.  https://books.google.ca/books?id=LDJ43xYxK5YC&pg=PA258&lpg=PA258&dq=Apollo+13+reentry+angle&source=bl&ots=3Cc9mzZNJR&sig=sLWSkkivIHidkiZ_qY3YjyKypaQ&hl=en&sa=X&ei=BemhUuf2NI6OkAfNioCoCg&redir_esc=y#v=onepage&q=Apollo%2013%20reentry%20angle&f=false  C. Clanet, F. Hersen, and L. Bocquet, “ Secrets of successful stone-skipping,” Nature 427, 29–29 (2004). https://doi.org/10.1038/427029a  To Avoid Overspending, Think of Money as Hours of Your Life originally aired September 26, 2018 https://omny.fm/shows/curiosity-daily/gardening-with-martian-soil-how-to-stop-overspendi  Follow Curiosity Daily on your favorite podcast app to learn something new every day withCody Gough andAshley Hamer — for free!  See omnystudio.com/listener for privacy information.

Pager
Oceans and Human Health with Neel Aluru

Pager

Play Episode Listen Later Apr 19, 2021 43:49


In this episode, Dr Neel Aluru joins us to discuss how toxicants in the ocean affect human health. Dr Aluru is an associate scientist at the Woods Hole Oceanographic Institute, where his research group investigates epigenetic and RNA mechanisms linking chemicals to human health.Topics include:The concept of a 'Developmental Origins of Health and  Disease'How scientists investigate chemicals in the OceanPolychlorinated biphenyls, and their effects on genes in the brainModel systemsGene editing tools, and the future directions of the lab's work

health ocean disease rna epigenetics human health gene editing neel marine biology woods hole oceanographic institute developmental origins
The Global Health Collective - With a Local Edge
1.2 Hunger and Poverty - How Can We Make Change? With Dr. Tina Moffat

The Global Health Collective - With a Local Edge

Play Episode Listen Later Nov 18, 2020 30:37


Did you know there is food insecurity in your own neighborhood? What can you do to change that? and what ARE you going to do about it? Join Dr. Tina Moffat as she discusses how to gain confidence in your abilities and seek to make sustainable change in your own community. During this episode - Shania Bhopa and Dr. Moffat analyze the disparities that exist within Hamilton to understand how local issues are global issues, particularly hunger, and poverty. Youth today need to take action and utilize their digital platforms to create change. Dr. Tina Moffat offers her advice to her "younger self" and how we can learn from her experiences. ______________________________________ Shania Bhopa is a current McMaster Global Health graduate student who is passionate about health communications and knowledge translation. She is the founder and executive director of The Canadian Courage Project, a GTA based non-profit organization striving to assist homeless youth with animal companions. She is also an educator, with a micro-credential to teach children and young people about the Sustainable Development Goals. Shania spends her free time learning about mental health and health promotion and is currently writing a wellness book with an aim to help women with their health and well-being. Dr. Tina Moffat's current research focuses on knowledge translation and support for pregnant women regarding the Developmental Origins of Health and Disease (DOHaD) as it relates to maternal diet and child health outcomes. This is a community study based in Hamilton called "Mothers to Babies" (M2B). As well, Moffat currently holds an SSHRC Research Engage Grant (2019-2020) to do research and evaluation of youth food programming at the Hamilton Community Food Centre (HCFC), part of a growing movement of Food Centres across Canada that move beyond charity models of food banks to support food insecure populations to access nutritious food in a dignified manner. Dr. Moffat has also done research on food security and dietary change among immigrants and refugees in Canada, based on a CIHR-funded research project called Changing Homes, Changing Food (2012-2015). Other research interests include vitamin D intake in North America, as well as the social and cultural determinants of child obesity.

Abuelas en Acción: A Podcast for Our Common Good
Abuela, Mama y Yo: Health for Latino Families

Abuelas en Acción: A Podcast for Our Common Good

Play Episode Listen Later Aug 31, 2020 31:02


Today Rebeca Marquez talks about Latinx health and nutrition.  Developmental Origins of Health and Disease (DOHaD) research tells us that a baby's health is impacted by three generations of her/his family.  This unique program doesn't blame mothers or families for their health but rather looks at social determinants including poverty, fear of deportation, unsafe neighborhoods as all factors in poor health.  Abuela, Mama y Yo engages family in becoming advocates for thriving families and communities.Support the show (https://www.familiasenaccion.org/donate/)

Live Healthy Be Well
Glyphosate Causes Multi-Generational Health Damage

Live Healthy Be Well

Play Episode Listen Later Nov 5, 2019 50:30


Key Takeaways: [0:27] Jeffrey Smith gives an introduction of today’s podcast with Dr. Skinner and the implications his research has on our grandchildren. “It turns out that when one person is exposed, their offspring's offspring's offspring could have really serious problems.” [2:44] Dr. Michael Skinner gives an overview of epigenetics and how changes can be passed through generations without affecting or changing DNA, or a nongenetic form of inheritance called Epigenetic Transgenerational Inheritance. [6:49] Dr. Skinner explains the research his team conducted on rats to show how effects from glyphosate don’t show up in the first generation, but are significant three generations later. [9:51] Dr. Skinner tells us about the flaws in Monsanto’s research regarding the toxicology of glyphosate. [10:12 - 10:54] “In the 80s we didn't really know that if you expose an animal, let's say early in life - early, put right after birth or something, to something that there really wouldn't be an effect then. But if you aged them out a year, you see all sorts of things happening and that concept is called the Developmental Origins of Health and Disease. In other words, when we get the disease -when we’re in their 50s or 60s, that has really nothing to do with what we're doing in our 50s and 60s. It had to do with your early life. It's a fetus, early postnatal, or even pubertal periods. It turns out that the environmental stressor changed the epigenetics of the DNA and those cells set its program, but it really doesn't lock in to do anything until later in life.” [14:03] Dr Skinner busts the myth that animal studies can’t really show us what will happen in humans. [16:18] Dr. Skinner lists the diseases found in the second and third generations of his study. Not only was he finding significantly high rates of disease among the rats, he was finding the same rates of certain diseases that are found in the human population. [20:45] Dr. Skinner explains the DDT exposure of the 1950s and the effects we have seen on the population today. [23:18] Why is generational toxicology going to be our most important step moving forward? [26:41] Dr Skinner breaks down how traits are passed from generation to generation through chemical processes. [28:03] “ Okay, so this Epigenetic Transgenerational Inheritance, so far, appears to be more permanently programmed.” [29:33] Dr. Skinner proposes a future where we may be able to prevent ancestral diseases. [32:55] Jeffrey suggests that a healthy diet can still encourage healthy gene expression and negate these ancestral diseases. Dr. Skinner backs up this claim by confirming that diet and lifestyle are huge promoters of these ancestral diseases and have a significant impact on our health. “ On a daily level, probably the biggest exposure we have is our diet; what we eat and how much we eat. “ [44:32] Dr. Skinner gives us advice on how to change the future. The single biggest influence we have is to pressure our government and industries. [47:57] Jeffrey shares his advice on how to stay safe!

The GP Show
#85 Developmental Origins of Health and Disease with Professor Craig Pennell

The GP Show

Play Episode Listen Later Aug 1, 2019 42:48


Professor Craig Pennell is Chair in Obstetrics and Gynaecology and Professor in Maternal-Fetal Medicine at the University of Newcastle (John Hunter Hospital). He is also a senior researcher at Hunter Medical Research Institute HMRI in the Mothers and Babies Research Centre within the Priority Research Centre in Reproductive Health and Chair of the National Scientific Advisory Group of Red Nose.   His research can best be categorised into personalised medicine in perinatal health and the developmental origins of health and disease. His research is focussed on the use of genetics and genomics to predict and prevent preterm birth and non-communicable diseases.  Over his research career, he has written more than 200 papers with 4 in Nature, 19 in Nature Genetics and 5 in Nature Communications. Today we discuss the Developmental Origins of Health and Disease (DOHaD). Further resources: https://dohadsoc.org/ DOHaD 2019 conference October 20-23 Melbourne = https://dohadsoc.org/dohad-world-congress/ Patients: https://thousanddays.org www.telethonkids.org.au https://www.telethonkids.org.au/information-for/parents-and-families/ Further episodes at www.facebook.com/thegpshow.podcast Rating the podcast 5 stars and leaving a review in iTunes is a great help. Enjoy Friends  

Healthy Births, Happy Babies
098: Stress & Depression’s Effect on Your Baby During Pregnancy and Beyond | Dr. Catherine Monk

Healthy Births, Happy Babies

Play Episode Listen Later Oct 30, 2017 33:29


Guest: Dr. Catherine Monk, a Professor in the Departments of Psychiatry, and Obstetrics & Gynecology, Director of Research at the Women’s Program, Columbia University Medical Center, and Research Scientist VI at the New York State Psychiatric Institute. In this episode, we will cover: How to have a developmental outlook throughout pregnancy and early childhood to really see how optimal of a time the transition to parenting is. When stress and depression affect pregnancy, find out how to help yourself as a mother and how to help your baby too. How understanding the importance of development and the environment could change the way you raise and interact with your child. Resources mentioned in the conversation: Developmental Origins of Health & Disease Podcast #071 about the movie, In-Utero Link to watch the movie, In-Utero About Dr. Catherine Monk: Dr. Catherine Monk is a Professor in the Departments of Psychiatry, and Obstetrics & Gynecology, Director of Research at the Women’s Program, Columbia University Medical Center, and Research Scientist VI at the New York State Psychiatric Institute. Originally trained as a clinical psychologist treating children and adults in a program that emphasized the developmental origins of psychopathology, Dr. Monk completed her postdoctoral research training in the Psychobiological Sciences via a National Institutes of Health fellowship at Columbia University in 2000, joining the faculty there a year later. A two-time recipient of the prestigious Brain & Behavior Research Foundation Young Investigator Award, her research has been continuously funded by the National Institutes of Mental Health since she her first support as NIH ‘K’ Career Development awardee in 2001. Dr. Monk’s research brings together the fields of perinatal psychiatry, developmental psychobiology, and neuroscience to focus on the earliest influences on children’s developmental trajectories — those that happen in utero and how to intervene early to prevent risk for mental health disorders in the future children. She is internationally recognized for her contributions to the Developmental Origins of Health and Disease Research model. Most recently, Dr. Monk has been awarded key roles on the NIH-wide ECHO project, Environmental influences on Children’s Health Outcomes — a seven year, nationwide effort to study early factors, including prenatal, in children’s health outcomes across 50,000 participants. She is a PI on one ECHO award, Investigator on another, and elected by her peers to a two-year term to the ECHO Executive Committee.

Aspire Natural Heath
Is Paleo dead? - DrG Interviews Anastasia Boulais & Jamie Scott

Aspire Natural Heath

Play Episode Listen Later Apr 21, 2017 73:03


At the Ancestral Health Symposium 2016 (AHS16), DrG sat down with two of his favorite Kiwi’s: Dr. Anastasia Boulais and Jamie Scott of the Ancestral Health Society of New Zealand. They had a wide-ranging discussion about the first AHS in 2011 and traveling to the US, the “death” of Paleo, the importance of traditional wisdom vs Scientism, the expanding perspective from our personal well-being to social issues, the need to get involved in policy making, and the 2017 AHSNZ conference, plus much more. Resources: Website - https://ancestralhealthnz.org Twitter - @primalmeded (Anastasia), @_Jamie_Scott, @AHealthSocNZ Jamie’s 1000 days (Developmental Origins of Health & Disease) talk - https://www.youtube.com/watch?v=boG4qMj9_mI At Aspire Natural Health we are experts at treating gut problems, autoimmune diseases, and hard to treat cases. If you'd like help please reach out to us at 425-202-7849 or info@aspirenaturalhealth.com Photo attribution: http://bit.ly/2oG8woS (Paleo catfish)

Anthropology
The developmental origins of health and disease: adaptation reconsidered

Anthropology

Play Episode Listen Later Jun 8, 2016 38:22


Ian Rickard (Durham) places the origins of the science of health and disease within a framework of evolutionary theory and a medical anthropology perspective (18 January 2016)

Clinician's Roundtable
Breaking Inter-Generational Cycles of Disease Determinism: The DOHaD Project

Clinician's Roundtable

Play Episode Listen Later May 27, 2014


Host: Matt Birnholz, MD "We are what our parents and grandparents ate, and how they lived," says Dr. Mark Hanson, Director of the Academic Unit of Human Development and Health at the University of Southhampton in the United Kingdom. This chilling but increasingly recognized prospect concerning intergenerational passsages of disease risk helped found the Developmental Origins of Health and Disease (DOHaD) study, a worldwide collaboration aimed at better understanding environmental to genetic determinants of health across multiple generations. In this discussion with host Dr. Matt Birnholz, Dr. Hanson highlights the science behind broadening our scope of individualized care to include both past and future generations of each patient.

Nottingham Medico-Chirurgical Society Archives
2008.01.16 Professor Mark Hanson “Developmental Origins of Health and Disease”

Nottingham Medico-Chirurgical Society Archives

Play Episode Listen Later Oct 7, 2013


Professor Mark Hanson “Developmental Origins of Health and Disease”