Podcasts about Sensitization

There are a number of theories that have been studied to try to explain addiction and drug use escalation, and thus to also create animal models of that behavior that can then serve to help develop treatments. One theory for escalation is that people feel worse and worse over time and so they take the drug to feel better. Another is that they just don't get as much of a reaction to the drug and so need more and more of it to get the euphoria. And then there's something called incentive salience, which is a craving for the drug.Read the full study here: Incentive salience, not psychomotor sensitization or tolerance, drives escalation of cocaine self-administration in heterogeneous stock rats | Neuropsychopharmacology Hosted on Acast. See acast.com/privacy for more information.

A free guide to FSM training is available there for licensed practitioners. https://frequencyspecific.com/how-to-choose-your-fsm-core-training Hosts: Carolyn McMakin, MA, DC, &  Kim Pittis, LCSP, (PHYS), MT In this Frequency Specific Microcurrent (FSM) podcast episode, the hosts discuss mindset and race preparation, including using FSM (even in a sauna), yoga, meditation, and balance work, and connect performance gains to often-neglected intrinsic foot muscles and tarsal/talus mobility. Dr. Carol Kim Pittis explains how restricted tarsal and talus motion can disrupt gait mechanics and how tools like an activator may stimulate proprioceptors. She then recounts a home visit with an 83-year-old man with four prior spine surgeries and severe chronic pain; a CT scan revealed extensive fusion (including pelvis), lateral vertebral shift, and hardware issues that changed the care plan away from forcing upright posture and toward safe walking, lower-leg/foot mobility, and symptom management. After targeted FSM protocols and supportive strategies, his leg circulation improved, and he became virtually pain-free, highlighting the importance of imaging, clinical judgment, and resetting goals and expectations. 00:00 Mindset for Racing 00:32 Foot Mechanics Matter 01:02 FSM Podcast Intro 01:28 Goals, Expectations, and Shoulds 03:13 Personal Best Breakdown 05:07 Tarsals, Talus, and Balance 10:41 Foot Model Show and Tell 15:04 House Call Spine Case 17:16 CT Scan Changes Everything 21:19 FSM Protocol and Recovery 29:58 Clinical Instinct and Authority 35:50 Imaging Stories and Running 36:52 Disc Healing and Imaging 37:48 When to Order Scans 39:27 Advocating for Imaging 41:45 Fall Prevention Reality 43:28 Processing Missed Care 45:19 Choosing the Right Modality 47:30 Knee and Shoulder Protocols 49:25 Safety and Sensitization 51:13 Goals and Hard Limits 52:40 Alcohol Gene Factoid 55:06 Continuing Education Nuggets 58:39 Practitioner Mindset Pivot 01:01:55 Deal Breakers and Buy In 01:04:19 Diet Negotiation Tactics  

Description:  Hosts Roz and Dr. Sanchez-Fueyo are joined by Somaya Zahran to discuss the key articles of the May issue of the American Journal of Transplantation. Somaya Zahran is a transplant nephrology fellow at the Mayo Clinic in Rochester. [03:06] Sensitization in organ transplantation: Assessment of Risk (STAR) 2025 meeting group report [08:55] The Banff 2024 Kidney Meeting Report: Rejection as a spectrum of phenotypes and focus on differential diagnostic reasoning [22:17] Normothermic versus hypothermic machine perfusion in kidney transplantation: A randomized controlled trial [27:36] Gene-edited pig cardiac xenotransplantation as a bridge to allotransplantation in infants: Progress in a pig-to-baboon model

  Ali Damron discusses practical strategies for managing nervous system sensitization, anxiety, and emotional regulation. She emphasizes the importance of acceptance, slowing down, and teaching the brain safety to build resilience.  Nervous system sensitization and regulation Fight or flight response and how to manage it Practical techniques for emotional resilience  sound bites "Fight or flight doesn't always look like a panic attack." "Reassurance often doesn't work when you're in threat mode." "Drop the pressure to fix everything; just be present." Chapters 00:00 Introduction to Nervous System Sensitization 02:49 Understanding Fight or Flight Response 05:51 The Impact of Stress on the Body 09:03 Navigating Anxiety and Emotional Processing 11:55 Changing Your Response to Anxiety 14:41 Slowing Down to Regulate Your Nervous System 17:54 Paying Attention to Pleasant Sensations 20:48 Personal Story of Grief and Resilience 23:39 Finding Hope and Solidarity in Healing  resources David Kessler's books on grief - https://www.amazon.com/s?k=David+Kessler Ali Damron's Instagram - https://www.instagram.com/ali_damron/ Ali's Resources:  Consults with Ali  BIOptimizers Magnesium Breakthrough 10% off using code ALIDAMRON10 www.alidamron.com/magnesium Master Your Perimenopause Course + Toolkit "Am I in Perimenopause?" Checklist.  What Hormone is Imbalanced? Quiz! Fullscript (Get 10% off all supplements) "How To Balance Your Hormones For Better Sleep, Mood, Periods and Energy" Free, On Demand Training Website  Ali's Instagram Ali's Facebook Group: Holistic Health with Ali Damron     

Leading up to May 1, the Department of Labour joins the UN and ILO in spotlighting workers' rights with a series of social and cultural events under the theme, "A Celebration of Workers."

CardioNerds (Dr. Hamza Patel, Dr. Jenna Skowronski, and Dr. Apoorva Gangavelli) discuss advanced heart failure and LVAD management with Dr. Mark Belkin, Advanced Heart Failure & Transplant Cardiologist, and Dr. Chris Salerno, Cardiothoracic Surgeon. They explore the nuances of right ventricular (RV) physiology, perioperative hemodynamic optimization, long-term complications, sensitization and transplant considerations, and the evolving role of GDMT in LVAD patients.  This episode highlights the delicate interplay between surgical and medical management in achieving optimal outcomes for patients living with durable mechanical circulatory support.Audio editing by CardioNerds Academy intern, student doctor, Pace Wetstein. Enjoy this Circulation 2022 Paths to Discovery article to learn about the CardioNerds story, mission, and values. CardioNerds Heart Success Series PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls “The right ventricle sets the stage.” — LVAD success hinges on RV performance; a struggling RV can turn a perfect LVAD surgery into a perfect storm.  “Watch the ratios.” — A PAPi < 2 and RA:PCWP >0.6 signal high risk for RV failure post-implant; trends and response to optimization matter more than static numbers.  “From hemocompatibility to hemodynamics.” — The LVAD field has moved from fighting pump thrombosis to mastering long-term RV failure and aortic insufficiency.  “Not all antibodies are created equal.” — LVAD-related sensitization often resolves post-transplant, reminding clinicians to interpret PRA trends in context.  “Recovery is possible.” — The RESTAGE-HF trial and emerging SGLT2 data hint at a new era: not just sustaining life with LVADs but restoring native heart function.  Notes Notes drafted by Dr. Hamza Patel. 1. Hemodynamic & Vasoactive Management of the RV  Use norepinephrine and vasopressin for pressor support; consider dobutamine as inotrope of choice.  Consider avoiding early milrinone due to hypotension and reduced coronary perfusion.  Use inhaled NO or epoprostenol selectively; institutional variation depends on cost and supply.  Key hemodynamic markers:  PAPi = (PA systolic – PA diastolic) / RA pressure.  PAPi < 2 → increased RV failure risk.  RA:PCWP ratio ≈ 0.6 normal; ≈ 1 → severe RV dysfunction.  RV reserve—the ability to improve these indices with optimization—is a stronger predictor of outcomes than baseline numbers alone.  NOTE: there is no robust data to guide vasoactive medical decision-making and there is substantial institutional variability in practive.  2. Long-Term LVAD Complications  MOMENTUM 3 trial: HeartMate 3 reduced pump thrombosis (10 → 1 %), stroke (14 → 5%), and GI bleed (77 → 43 %).  Persistent issues: driveline infections, RV failure, and aortic insufficiency.  Driveline care: silver sulfadiazine (Silvadene) cream linked to lower infection rates (Cowher & Kenmore 2025).  Field now focuses on hemodynamic-related adverse events—the next frontier in LVAD outcomes.  Innovation ahead: smaller drivelines and fully implantable LVADs to eliminate infection risk.  3. Sensitization and Transplant Candidacy  LVADs may induce de novo HLA antibodies, complicating transplant matching.  These antibodies tend to be transient and less cytotoxic, often resolving post-transplant.  Sensitization degree varies by device and patient; management strategies are center-dependent.  The field is redefining which antibodies are truly LVAD-induced versus incidental.  4. GDMT & Myocardial Recovery  GDMT data in LVAD patients limited—excluded from major HFrEF trials.  RESTAGE-HF: aggressive GDMT post-LVAD yielded 52% explant rate within 18 months.  SGLT2 inhibitors: emerging evidence of reverse remodeling and reduced LV size (Belkin et al., THT 2025).  GDMT promotes recovery but requires cautious titration to avoid hypotension and RV strain.  5. Future of LVAD Therapy  The fully implantable LVAD remains the goal—wireless energy, no driveline, and fewer infections.  Short-term focus: device miniaturization, improved energy efficiency, and better hemocompatibility.  HeartMate 3 remains gold standard until next-generation systems mature.  References Mehra MR et al. NEJM 2018 — MOMENTUM 3 Final Report.  Takeda K et al. JHLT 2020 — Predictors of RV Failure After LVAD.  Imamura T et al. Circ Heart Fail 2017 — Hemodynamics and RV Adaptation Post-LVAD.  RESTAGE-HF Trial, JHLT 2019.  Cowher J, Kenmore C et al. 2025 — Driveline Care & Infection Outcomes.  Belkin M et al. THT 2025 — SGLT2 Inhibition and Reverse Remodeling Post-LVAD. 

In this episode of The Healers Café, Manon Bolliger, speaks to health coach and nervous system expert Mitch Webb who shares his powerful journey from biohacking and forcing his body to heal, to embracing trauma-informed, somatic, and nervous system-based healing. Discover how shifting from survival mode to self-trust and gentle awareness can transform chronic symptoms and expand your capacity for life. For the transcript and full story go to: https://www.drmanonbolliger.com/mitch-webb     Highlights from today's episode include:  Force vs. healing: Mitch describes how intense biohacking, strict diets, and "overwhelming force" helped only temporarily—true, sustainable healing began when he addressed unresolved trauma and his nervous system. Sensitization & safety: Mitch explains sensitization (chronic hyper-vigilance, fear, and shrinking life) and how building safety, capacity, and self-trust through somatic and nervous system work allowed his symptoms to ease and his life to expand. Bowen as a doorway to safety: Manon highlights how Bowen therapy can gently guide the body out of constant sympathetic overdrive, helping people slow down, become observers of their physical experience, and open another doorway into the deeper healing process.   ABOUT MITCH WEBB: Mitch Webb is a health coach and nervous system expert who helps clients heal from the inside out. He works one-on-one with people dealing with gut issues, anxiety, autoimmune symptoms, fatigue, burnout, and other chronic conditions that haven't resolved through conventional approaches. Mitch blends functional health principles with deep nervous system work to get to the root cause—so healing isn't just a quick fix, it's sustainable. His approach is trauma-informed, body-based, and tailored to the individual. If you're ready to feel like yourself again, Mitch helps you get there. To contact, visit mitchwebb.com Core purpose/passion: My core mission is to help people heal their nervous systems so they can stop chasing symptoms and start trusting their bodies again. I'm here to guide folks out of survival mode and back into a life that feels safe, aligned, and fully alive –  Facebook |  Instagram |  LinkedIn  |  Website | Freebie | YouTube  ABOUT MANON BOLLIGER, RBHT, FCAH: As a retired Naturopath 1992-2021, I saw an average of 150 patients per week and have helped people ranging from rural farmers in Nova Scotia to stressed out CEOs in Toronto to tri-athletes here in Vancouver. My resolve to educate, empower and engage people to take charge of their own health is evident in my best-selling books:  'What Patients Don't Say if Doctors Don't Ask: The Mindful Patient-Doctor Relationship' and 'A Healer in Every Household: Simple Solutions for Stress'. and What if Your Body is Smarter than You Think?  I am the Founder & CEO of The Bowen College Inc. which teaches BowenFirst™ Therapy and holds transformational workshops to achieve these goals. So, when I share with you that LISTENing to Your body is a game changer in the healing process, I am speaking from expertise and direct experience". Mission: A Healer in Every Household! For more great information to go to her weekly blog:  http://bowencollege.com/blog.  For tips on health & healing go to: https://www.drmanonbolliger.com/tips Follow: Manon Bolliger website  | Linktr.ee | Rumble | Gettr  | Facebook | Instagram | YouTube | Twitter | LinkedIn | Follow: Bowen College Inc. | Facebook | Instagram  | LinkedIn | YouTube | Twitter | Rumble | Locals ABOUT THE HEALERS CAFE: Manon's show is the #1 show for medical practitioners and holistic healers to have heart to heart conversations about their day to day lives. Subscribe and review on your favourite platform: iTunes | Google Play | Spotify | Libsyn | iHeartRadio | Gaana | The Healers Cafe | Radio.com | Medioq | Audacy |   Follow The Healers Café on FB: https://www.facebook.com/thehealerscafe   Remember to subscribe if you like our videos. Click the bell if you want to be one of the first people notified of a new release.   * De-Registered, revoked & retired naturopathic physician after 30 years of practice in healthcare. Now resourceful & resolved to share with you all the tools to take care of your health & vitality!  

 In this episode of the Research Bites Podcast, Dr. Kristina Spaulding dives deep into two foundational—but often under-discussed—forms of non-associative learning: sensitization and habituation. Drawing on research and classic learning theory, she explains what these processes are, how they differ, why they matter, and how they show up every day in companion animals. Dr. Spaulding connects the research to practical strategies you can use right away. From monitoring behavior and adjusting stimulus intensity to incorporating conditioning and systematic desensitization, this episode offers clear guidance for helping animals move toward calmer, more adaptive responses.  This episode will help you learn how to apply these principles thoughtfully in real-world training and behavior work. Whether you're a trainer, behavior consultant, or simply passionate about science-informed practice, this episode will deepen your understanding of how animals learn—and how you can support them more effectively.For more information, please check out my website and social media links below! Website: https://sciencemattersllc.com/ Unlocking Resilience: https://sciencemattersllc.com/unlocking-resilience Research Bites: https://sciencemattersllc.com/research-bites Join the Science Matters newsletter Facebook ...

What does it take to make a city nearly rabies-free without harming a single stray dog? How can compassion transform centuries-old practices of animal exploitation into humane alternatives? In this powerful episode we sit down with Timmie Kumar, Managing Trustee of Help in Suffering and a pioneer in India's animal welfare movement.Why This Episode Matters:Animal welfare in India is often overshadowed by human struggles, but compassion is not a zero-sum game. Timmie Kumar reveals how Jaipur became a model for humane street dog management while challenging animal cruelty in festivals, weddings, and traditions. She also stresses the need to regulate pet ownership, end animal testing, and build empathy through education so kindness becomes a way of life.Lessons in Compassion & Change:Jaipur's rabies-free success shows that large-scale humane interventions can save lives.Abandonment and overbreeding must end.Sensitization of police/authorities can transform society.From animal testing to zoos and sacrificial rituals, cruelty must never be justified as entertainment or tradition.Connect with UsMohua Chinappa: https://www.linkedin.com/in/mohua-chinappa/The Mohua Show: https://www.themohuashow.com/Connect with the Guest:Timmie Kumar: https://www.instagram.com/timmie.kumar/ Help in Suffering: https://www.instagram.com/helpinsuffering/ References:Help in Suffering, PETA India on Zoos & Elephants, General Animal Welfare Legislation in IndiaFollow UsYouTube: https://www.youtube.com/@TheMohuaShowLinkedIn: https://www.linkedin.com/company/themohuashow/Facebook: https://www.facebook.com/themohuashowInstagram: https://www.instagram.com/themohuashow/More Episodes Like This:Gargi Rawat: https://www.youtube.com/watch?v=Vc3xZ8wf5do For any other queries EMAILhello@themohuashow.comDisclaimerThe views expressed by our guests are their own. We do not endorse and are not responsible for any views expressed by our guests on our podcast and its associated platforms. Hosted on Acast. See acast.com/privacy for more information.

Wenn es irgendwo schmerzt, will der Körper uns sagen, dass etwas nicht stimmt. Was aber, wenn keine Ursache gefunden wird oder der Schmerz chronisch ist? Millionen von Menschen in Deutschland leiden an chronischen Schmerzen. Trotzdem wird kaum auf das Phänomen geschaut. Chronischer Schmerz kann Menschen über Jahre begleiten. Doch auch wenn er nicht chronisch, sondern akut auftritt: Fast jede und jeder hat irgendwann einmal mit Schmerzen zu kämpfen. Host Beke Schulmann und Autorin Daniela Remus gehen der Sache auf den Grund: Warum haben wir Schmerzen? Wie entstehen Schmerzen und wie sollte man mit ihnen umgehen, damit sie nicht chronisch werden? Was hat das Geschlecht mit dem Schmerzempfinden zu tun? HINTERGRUNDINFORMATIONEN: Ein internationales Team hat ein Gen identifiziert, das dazu führt, dass Menschen keine Schmerzen empfinden können: Transcriptional regulator PRDM12 controls the development of pain perception. Nature Genetics, 2015, doi:10.1038/ng.3308. UKE in Hamburg, Schmerztherapie: https://www.uke.de/kliniken-institute/zentren/ambulanzzentrum-medizinisches-versorgungszentrum-(mvz)/fachbereiche/schmerztherapie/index.html Sölle, A., Bartholomäus, T., Worm, M., Klinger, R. (2014). How to psychologically minimize scatching impulses: benefits of placebo effects on itching using classical conditioning and expectancy. Zeitschrift für Psychologie, Vol. 222(3):140–147. DOI: 10.1027/2151-2604/a000183. Irnich, Dominik (2022): Grundlagen der Mikrosystemakupunktur und ihre Anwendung bei Ellenbogenbeschwerden. Deutsche Zeitschrift für Akupunktur, Bd. 65, Nr. 3: S. 142-146 Meergans, Christine und Irnich, Dominik (2021): Inhaltlicher Bericht zu den Bayerischen Schmerztagen 2021. 20-jähriges Jubiläum der Integrativen Schmerztherapie am LMU Klinikum. Deutsche Zeitschrift für Akupunktur, Bd. 64, Nr. 4: S. 310-315 Hohn VD, Tiemann L, Bott FS, May ES, Fritzen C, Nickel MM, Gil Ávila C, Ploner M. Neurofeedback and attention modulate somatosensory alpha oscillations but not pain perception. PLoS Biol. 2025; 23(1):e3002972. doi: 10.1371/journal.pbio.3002972. Sensitization of the Nociceptive System in Complex Regional Pain Syndrome. Reimer M, Rempe T, Diedrichs C, Baron R, Gierthmühlen J. PLoS One. 2016 May 5;11(5):e0154553. Complex regional pain syndromes: the influence of cutaneous and deep somatic sympathetic innervation on pain. Schattschneider J, Binder A, Siebrecht D, Wasner G, Baron R. Clin J Pain. 2006 Mar-Apr;22(3):240-4. Hier geht's zur Schmerzmittelseite bei ARD Gesund: ardgesund.de/schmerzmittel Hier geht's zur Synapsenseite: https://www.ndr.de/nachrichten/podcastsynapsen100.html Habt ihr Feedback oder einen Lifehack aus der Welt der Wissenschaft? Schreibt uns gerne an synapsen@ndr.de. Und noch ein Hörtipp: Abzocke oder Heilung? Welche Therapien gegen Long Covid wirklich helfen könnten. Darum geht's im Podcast Quarks Science Cops in der ARD Audiothek: https://1.ard.de/syn_x_science_cops

Wenn es irgendwo schmerzt, will der Körper uns sagen, dass etwas nicht stimmt. Was aber, wenn keine Ursache gefunden wird oder der Schmerz chronisch ist? Millionen von Menschen in Deutschland leiden an chronischen Schmerzen. Trotzdem wird kaum auf das Phänomen geschaut. Chronischer Schmerz kann Menschen über Jahre begleiten. Doch auch wenn er nicht chronisch, sondern akut auftritt: Fast jede und jeder hat irgendwann einmal mit Schmerzen zu kämpfen. Host Beke Schulmann und Autorin Daniela Remus gehen der Sache auf den Grund: Warum haben wir Schmerzen? Wie entstehen Schmerzen und wie sollte man mit ihnen umgehen, damit sie nicht chronisch werden? Was hat das Geschlecht mit dem Schmerzempfinden zu tun? HINTERGRUNDINFORMATIONEN: Ein internationales Team hat ein Gen identifiziert, das dazu führt, dass Menschen keine Schmerzen empfinden können: Transcriptional regulator PRDM12 controls the development of pain perception. Nature Genetics, 2015, doi:10.1038/ng.3308. UKE in Hamburg, Schmerztherapie: https://www.uke.de/kliniken-institute/zentren/ambulanzzentrum-medizinisches-versorgungszentrum-(mvz)/fachbereiche/schmerztherapie/index.html Sölle, A., Bartholomäus, T., Worm, M., Klinger, R. (2014). How to psychologically minimize scatching impulses: benefits of placebo effects on itching using classical conditioning and expectancy. Zeitschrift für Psychologie, Vol. 222(3):140–147. DOI: 10.1027/2151-2604/a000183. Irnich, Dominik (2022): Grundlagen der Mikrosystemakupunktur und ihre Anwendung bei Ellenbogenbeschwerden. Deutsche Zeitschrift für Akupunktur, Bd. 65, Nr. 3: S. 142-146 Meergans, Christine und Irnich, Dominik (2021): Inhaltlicher Bericht zu den Bayerischen Schmerztagen 2021. 20-jähriges Jubiläum der Integrativen Schmerztherapie am LMU Klinikum. Deutsche Zeitschrift für Akupunktur, Bd. 64, Nr. 4: S. 310-315 Hohn VD, Tiemann L, Bott FS, May ES, Fritzen C, Nickel MM, Gil Ávila C, Ploner M. Neurofeedback and attention modulate somatosensory alpha oscillations but not pain perception. PLoS Biol. 2025; 23(1):e3002972. doi: 10.1371/journal.pbio.3002972. Sensitization of the Nociceptive System in Complex Regional Pain Syndrome. Reimer M, Rempe T, Diedrichs C, Baron R, Gierthmühlen J. PLoS One. 2016 May 5;11(5):e0154553. Complex regional pain syndromes: the influence of cutaneous and deep somatic sympathetic innervation on pain. Schattschneider J, Binder A, Siebrecht D, Wasner G, Baron R. Clin J Pain. 2006 Mar-Apr;22(3):240-4. Hier geht's zur Schmerzmittelseite bei ARD Gesund: ardgesund.de/schmerzmittel Hier geht's zur Synapsenseite: https://www.ndr.de/nachrichten/podcastsynapsen100.html Habt ihr Feedback oder einen Lifehack aus der Welt der Wissenschaft? Schreibt uns gerne an synapsen@ndr.de. Und noch ein Hörtipp: Abzocke oder Heilung? Welche Therapien gegen Long Covid wirklich helfen könnten. Darum geht's im Podcast Quarks Science Cops in der ARD Audiothek: https://1.ard.de/syn_x_science_cops

One of the most common questions we hear from people working through anxiety disorders and OCD is: "How long is this going to take?" In this episode, Drew and Josh tackle the timeline question head-on—but probably not in the way you're expecting.We explore why asking "how long until I recover?" might be the wrong question, and why shifting to "how long until I'm desensitized?" can be a game-changer in how you approach your anxiety journey. We discuss the reality that there's no universal timeline, no magic number of weeks, and why that's actually okay.In this episode:Why the concept of "recovery" as a finish line may not be helpful for anxiety disordersThe difference between recovery and desensitizationHow urgency and pressure can actually slow your progressWhy some people seem to progress faster than others (and why that doesn't matter)The role of self-compassion, patience, and realistic expectationsWhy hard days are a normal part of the process—even after significant progressHow perfectionism and the need for certainty can keep you stuckWe also share inspiring "Did It Anyway" stories from listeners who are moving forward with their lives—traveling, attending events, and even jumping into mosh pits—alongside their anxiety, not waiting for it to disappear first.Whether you're struggling with panic disorder, agoraphobia, OCD, health anxiety, or other anxiety disorders, this episode offers a realistic, compassionate perspective on what it means to make progress and why the journey looks different for everyone.---Want a way to ask questions about this episode or interact with us and other Disordered listeners?  The Disordered app is nearing release! ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Visit our home page and get on our mailing list for more information..---Struggling with worry and rumination that you feel you can't stop or control? Check out ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Worry and Rumination Explained⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠, a two hour pre-recorded workshop produced by Josh and Drew. The workshop takes a deep dive into the mechanics of worrying and ruminating, offering some helpful ways to approach the seemingly unsolvable problem of trying to solve seemingly unsolvable problems.-----Want to ask us questions, share your wins, or get more information about Josh, Drew, and the Disordered podcast? Send us an email or leave a voicemail on our website.

In this intriguing conversation, Sathiya and Shawn answered many questions from our clients, and delve into various aspects of mental and emotional health, particularly focusing on the challenges of overcoming triggers, emotional dependence, and the journey towards freedom from addiction. They discuss the importance of understanding the root causes of these issues, the nature of temptation, and the distinction between sobriety and true freedom. The conversation emphasizes the need for self-awareness, healing, and the role of community support in achieving lasting change.   DCIC Always – Join The Brotherhood (and get coached by Sathiya) For Less Than $2/day   Know more about Sathiya's work:   Submit Your Questions (Anonymously) To Be Answered On The Podcast TLR Always – Get A Free Copy of The Last Relapse, Your Blueprint For Recovery Watch Sathiya on Youtube For More Content Like This   Chapters:  (00:00) Understanding Triggers and Sensitization (06:28) Emotional Dependence and Root Pain (16:02) Navigating Temptation and Lust (26:11) Replacing Addictions and Destructive Behaviors (30:49) Balancing High Standards and Managing Stress (36:14) Freedom vs. Sobriety: Overcoming Lustful Thoughts

Scientific Sense ® by Gill Eapen: Prof. Kent Berridge is professor of Psychology and Neuroscience at the University of Michigan. His research includes Addiction, Psychology, Emotion and Brain & Behavior. Please subscribe to this channel:https://www.youtube.com/c/ScientificSense?sub_confirmation=1

Are you wondering why your chronic pain keeps getting worse — even when your scans are clear and your doctors say nothing is wrong?In this second installment of my three part podcast series inside The Chronic Pain Experience Podcast, we dive into one of the most frustrating questions people with persistent pain face:Why is my pain not going away — and why does it feel like it's getting worse over time?You'll learn about a key but often-overlooked piece of the chronic pain puzzle:Sensitization — when your nervous system becomes hypersensitive and overprotective, amplifying pain signals even in the absence of ongoing injury.We'll break down the science in simple terms, explore how pain pathways become overactive, and explain what you can do about it — especially if you've already tried everything and feel stuck.If you're living with fibromyalgia, CRPS, chronic back pain, pelvic pain, or pain after injury or surgery that just won't go away… this episode is for you.Rate, Review & Follow on Apple PodcastsIf this episode resonated with you, it would mean the world if you'd take a moment to rate and review The Chronic Pain Experience Podcast on Apple Podcasts.Your words help me reach more people who are living with pain and looking for a different path forward — one that leads to hope, healing, and a life well-lived.Click HERE then head to the show page, scroll to the bottom, tap the five stars, and write a quick review. Let me know what stood out most for you — I read every single one!Want to know what might really be keeping you stuck?Here's your next step:Step 1: Click here to take the Sensitization Quiz to see if your nervous system might be contributing to your pain.Step 2: Click here to book a Free Strategy Call with me. We'll talk about what's working, what's not, and what your next best step could be.

Interactive

An interview with Rosalito, Graphic Designer.  In this compelling interview, Rosalito shares how an upgraded Wi-Fi router triggered an immediate and life-altering reaction, leading her to recognize and eliminate wireless technology from her life. She reflects on years of anxiety, tinnitus, and immunity issues that she now connects to prolonged EMF exposure—all of which disappeared after removing wireless devices. Keith and Rosalito discuss the social isolation that comes with EMF sensitivity, the widespread denial of wireless addiction, and the medical validation she received that confirmed her only solution was complete avoidance. Rosalito now dedicates her work to raising awareness through her graphic design and website, Rosalito.Art, reaching those who might never actively seek out EMF information. They explore the societal implications of wireless dependence and the urgent need for education, shielding strategies, and informed remediation. Despite the hardships, Rosalito considers her experience a blessing, giving her clarity and purpose in protecting herself and helping others navigate the growing electromagnetic landscape. Hey this is Keith, this month I'm sharing 3 recent episodes from the EMF Remedy Premium podcast so you can see what we've been up to recently -- behind the pay wall.As I record this brief announcement, we have 118 episodes carefully crafted to support both the winning mindset and technical tactics needed to survive the now ubiquitous electromagnetic poisoning.Two new changes to our podcast subscription model -- We're now offering a 7-day free trial, for thoseSupport the showContinue the journey with the EMF Remedy Premium Podcast, with over 110 episodes and counting! Keith Cutter is President of EMF Remedy LLChttps://www.emfremedy.com/YouTube Channel: https://www.youtube.com/channel/UCp8jc5qb0kzFhMs4vtgmNlgKeith's SubstackThe EMF Remedy Podcast is a production of EMF Remedy LLC

Check out Dr. Mina's top picks for skin care here. Download the free eBook 'Skincare Myths Busted' here. Nails aren't just there to show off your favorite polish or nail art—they're a direct reflection of your overall health (yep, just like your skin). With the rise of gel nails, dip powders, and intricate manicures, it's more important than ever to find a balance between nails that look great and are healthy, too. While these trends can take your style to the next level, they also come with potential risks like allergic reactions, infections, and long-term nail damage.  Tune into this week's podcast with Dr. Carina Woodruff as she answers key questions on nail care, from the safety of manicures and pedicures to the risks at the nail salon. She shares her top 3 tips for beautiful nails and explains how the rise of at-home nail kits may be contributing to acrylate allergic contact dermatitis (ACD).  Key Takeaways: - Patch testing helps identify triggers for skin reactions. - Nail treatments can cause allergic reactions in unexpected areas. - Acrylic and gel nails can lead to sensitization over time. - Gentle nail care practices can prevent infections and damage. - Fungal infections can spread in nail salons if hygiene is poor. - Top coats in nail polish can harbor fungus and spread infections. - UV light used for gel nails can cause skin damage. - Choosing a reputable salon is crucial for nail health. - Taking breaks from nail treatments can promote healthier nails. - Regular check-ups with a dermatologist are important for nail health. In This Episode: (04:43) Introduction to Dermatology and Patch Testing (06:00) The Impact of Nail Treatments on Skin Health (08:33) Understanding Allergic Reactions and Sensitization (16:23) Nail Care Practices and Their Risks (18:31) Choosing the Right Nail Salon (20:57) Safety of Gel Nails and UV Light Exposure (23:24) Top Tips for Healthy Nails (25:28) Importance of Full Body Skin Checks Dr. Woodruff is the Director of the Epiphany Skin Allergy Institute in Dallas, Texas. Before joining Epiphany, Dr. Woodruff was an assistant professor of dermatology at the University of California, San Francisco where she was also Associate Director of the Contact Dermatitis Unit and Director of Medical Student Education. Her formal education and training include: Harvard University (Cambridge, MA) – BA, Social and Cognitive Neuroscience  Yale School of Medicine (New Haven, CT) – Doctor of Medicine Kaiser Permanente Medical Center (Oakland, CA) – Internal Medicine Internship University of California, San Francisco (San Francisco, CA) – Dermatology Residency Dr. Woodruff's ongoing involvement in research has facilitated a host of publications in major dermatology journals. She enjoys teaching medical students and residents and is a regular lecturer at national conferences. She co-founded VETTED Dermlab, a hypoallergenic skincare brand, and is an associate editor for the contact allergy journal Dermatitis.  Dr. Woodruff is originally from São Paolo, Brazil and is fluent in Portuguese. She grew up in Orlando, Florida. In her spare time, she enjoys exploring Dallas, traveling, and spending time with her family husband (Henry), daughter (Sienna - 5yo), son (Hughie- 3yo), and her King Charles Spaniel, Poppy. Find Dr. Carina Woodruff here: Instagram: https://www.instagram.com/drcarinawoodruff/?hl=en Linkedin: https://www.linkedin.com/in/carina-woodruff-md-faad-74b65ba4/ Clinic website: https://www.epiphanydermatology.com/location/dallas-tx/ https://vetteddermlab.com Follow Dr. Mina here:-  https://instagram.com/drminaskin https://www.facebook.com/drminaskin https://www.youtube.com/@drminaskin https://www.linkedin.com/in/drminaskin/ For more great skin care tips, subscribe to The Skin Real Podcast or visit www.theskinreal.com Baucom & Mina Derm Surgery, LLC Website- https://www.atlantadermsurgery.com/ Email - scheduling@atlantadermsurgery.com Contact - (404) 844-0496 Instagram - https://www.instagram.com/baucomminamd/ Thanks for listening! The content of this podcast is for entertainment, educational, and informational purposes and does not constitute formal medical advice.

Welcome to another enlightening episode of the StreetSmart Wisdom Podcast! I'm your host, Steve Stein, founder of Better Listen and Wisdom Feed Plus. Today, we have the immense privilege of conversing with Dr. Rick Hanson, a best-selling author and renowned speaker, whose work beautifully intertwines mindfulness, clinical psychology, and neuroscience. In this episode, we dive deep into the concept of sensitization and neuroplasticity, exploring how our inner world shapes our existence and overall well-being. Rick shares his journey—from a young boy grappling with feelings of inadequacy and social awkwardness to becoming a leading figure at the fascinating intersection of brain science and contemplative wisdom. We also reflect on the impermanence of life through the poignant metaphor of a sand mandala, and Rick offers street smart wisdom on how to navigate this ever-changing world with resilience and inner peace. This episode is rich with insights and practical takeaways that will inspire you to cultivate a deeper understanding of yourself and your place in the world. So, buckle up and get ready for a thought-provoking conversation with Dr. Rick Hanson, right here on the StreetSmart Wisdom Podcast.   TIMESTAMP: 00:00 Street Smart Wisdom Podcast with Steve Stein. 04:04 UCLA at 16, evolved to psychology intersection. 07:12 Socially awkward, turned to inner world exploration. 11:57 Everything is cloud-like; live with less attachment. 15:34 Life is transient, memories fade over time. 19:02 Skipping grades poses social challenges for students. 22:53 Realization: It was up to me. 26:39 Join WisdomFeed Plus for curated wellness content. 27:42 Begin your peaceful journey at surfingthetsunami.com   Connect with us: Facebook: https://bit.ly/FBpageWF Instagram: https://bit.ly/RealWisdomFeed WisdomFeed Website: https://bit.ly/WisdomFeedHome BetterListen Website: https://bit.ly/BetterListenWebsite

Atopic dermatitis is the single most common chronic condition in the world, but it's also the most misunderstood and mistreated. People who struggle with it endure years of discomfort, a drop in their quality of life, a revolving door of doctors, reams of blood tests and a multitude of treatments. These treatments often focus on food and finding out what they can stop eating to get better. Though this is well-intentioned advice, it is misguided. The food you eat isn't the root cause of eczema. Growing data show that eczema is what causes food allergies. This changes everything about how eczema is treated, and also how to prevent it in infants. For high-risk babies, early and frequent exposure to food can significantly reduce the chance of atopic dermatitis and potentially set them up for an allergy-free life. In this episode, I'm joined by the Chief Medical Officer at Snö Asthma & Allergy, Dr. Stuart Carr. He shares the truth about atopic dermatitis, and why there are more treatment options on the table other than avoiding certain foods and hoping for the best.  Things You'll Learn In This Episode  -Sensitization vs. true allergy  Food sensitivity and allergy are two very different things that often get mixed up. How do doctors determine if you're allergic to something? -The right way to restrict your diet  Many people use elimination diets to try and combat allergies. How do you do this without actually increasing your chance of allergy? -Early and often exposure is key Parents of infants prone to eczema often delay the introduction of certain foods, could this actually make the likelihood of allergy higher? -Food in mouth, but not on skin Atopic dermatitis patients think eating certain foods will trigger a reaction. What actually triggers a reaction?  Guest Bio Dr. Carr has been Chief Medical Officer at Snö Asthma & Allergy in Abu Dhabi since January 2019, having spent the previous 20 years in academic clinical allergy practice in Edmonton, Canada.  He was an Associate Clinical Professor at the University of Alberta, and is also a Past-President of the Canadian Society of Allergy and Clinical Immunology, and a reviewer for Allergy, Asthma & Clinical Immunology, the journal of the CSACI. His primary interests are pediatric asthma, food allergy, and eosinophilic esophagitis, and Dr. Carr is currently involved in a Canada-wide collaboration examining the safety and effectiveness of oral immunotherapy for peanut and other food allergies in preschool children. To learn more follow @allergydoc4kidz on Instagram   About Your Host Hosted by Dr. Deepa Grandon, MD MBA, triple board-certified physician with over 23 years of experience working as a Physician Consultant for influential organizations worldwide. Dr. Grandon is the founder of Transformational Life Consulting (TLC) and an outspoken faith-based leader in evidenced-based lifestyle medicine.   ​​TLC is presenting this podcast as a form of information sharing only. It is not medical advice or intended to replace the judgment of a licensed physician. TLC is not responsible for any claims related to procedures, professionals, products, or methods discussed in the podcast, and it does not approve or endorse any products, professionals, services, or methods that might be referenced. Check out this episode on our website, Apple Podcasts, or Spotify, and don't forget to leave a review if you like what you heard. Your review feeds the algorithm so our show reaches more people. Thank you!

The Medical Disruptor podcast is back, and we're blowing the lid off the toxic secret that's driving the hidden epidemic of chronic illness. Is mold secretly sabotaging your sanity? Mold toxicity isn't just about musty basements. It's the hidden menace wreaking havoc on your brain, gut, and entire body.  From "unexplained" anxiety to autoimmune flare-ups and cognitive decline, mold's fingerprints are all over our most baffling health crises. In this mind-blowing episode, I sit down with mold mastermind Dr. Neil Nathan to expose the truth about this overlooked culprit.  We're diving deep into why your "mental health" issues might actually be mold colonizing your brain, the shocking link between mold and conditions like POTS that leave doctors scratching their heads, and how mold toxicity steals your vitality, hijacks your potential, and makes you question your own reality. Dr. Nathan isn't just a colleague - he's a true Medical Disruptor whose work has revolutionized how I unmask mold's destruction in my own patients. Here's the truth: Mold toxicity can derail your life, but it doesn't have to define it. Are you ready to stop being a victim of invisible toxins and become the ultimate biohacker of your own health?  Your toxic-free transformation starts now. Don't waste another day feeling dismissed by doctors or defeated by mystery symptoms.  You have more power to detox and heal than you ever imagined - it's time to tap into it. Tune in and arm yourself with the knowledge to reclaim your health from mold's toxic grip.    00:00 Introduction 03:00 Dr. Neil Nathan's Journey to Medicine  06:00 Transition to Mold and Mycotoxins 09:00 Exploring Chronic Pain and Fibromyalgia 12:00 Discovering Mold Toxicity 15:00 Collaborating with Dr. Shoemaker on Mold Treatment 18:00 Mold's Impact on Health and Sensitivity  21:00 Understanding Mast Cell Activation and Vagal Dysfunction 24:00 How Mold and Lyme Disease Are Linked 27:00 Treating Mold Toxicity: Steps and Challenges 30:00 The Role of Sensitization in Mold and Lyme Disease 33:00 Neurological Impact of Mold: Brain Fog and Dementia Risks 36:00 Supporting Sensitive Patients and Available Resources 39:00 Encouraging Patients to Seek Proper Treatment 42:00 Conclusion and Final Thoughts   Check us out on social media: drefratlamandre.com/instagram  drefratlamandre.com/facebook  drefratlamandre.com/tiktok

✅ Watch the MASTERCLASS on Low Back Pain & Sciatica. https://www.shapeshiftwellness.com/LBP-masterclass . If you have chronic low back pain or sciatica, it's easy to think that the pain is all coming from tissue damage like a disc bulge, a disc herniation, disc degeneration, tight muscles, or a pinched nerve. . Research shows that in most cases of chronic pain, a large portion of the pain is NOT from damage, but rather from inflammation and hypersensitization of the nerves in the muscles, joints, and disc, through a process called peripheral sensitization. . Peripheral sensitization can make chronic low back pain and sciatica much worse by creating hypersensitivity to normal, non-damaging activities or movements. This is crucial in understanding the difference between safe pain and unsafe pain during chronic low back pain and sciatica rehab. . . #lowbackpain #lowbackpainrelief#lowbackpainexercises #discherniation #sciaticarelief#sciatica #sciaticatreatment

In this video, I take you step by step through a playful sensory sensitization exercise! This is another great way to use our external world to increase our internal awareness. It's also important in getting us thinking about the ways we have become desensitized as a result of trauma and what "waking up the senses" really means. I also share about how a client of mine recently used interoception to decide whether or not a relationship was working for her!#beyondsurviving #sexualabusesurvivor #nervoussystemregulation #interoception #usethesenses #internalawareness #incestsurvivor #healingsexualtrauma #foryou #viral #coachrachelsays #coaching #toolsthatwork #healing #sensitization #wakeupthesensesSupport this show http://supporter.acast.com/beyond-surviving. Hosted on Acast. See acast.com/privacy for more information.

Let's work on feeling the water.  Sensitization drills to highten your feel!#swimming #feelthewater #liquiddeathmainset @liquiddeath Visit www.nlscak.coach for additional practice videos. #swimming #swimcoach #nlscak #nlscakpracticevideo #usaswimming #worldaquatics #alaskaswimming #swimfaster #thelegsfeedthebear @usaswimming

Small and Medium-sized Enterprises (SMEs) are growing concerned over business interruptions and cyberattacks, especially in Germany.  There is a notable gap in organizational measures relating to information security despite current safeguards, particularly in the areas of awareness and emergency preparedness.Professor Margit Scholl from TH Wildau is leading research across an evolving landscape of cybersecurity threats. Her work highlights how important it is to equip SMEs in Germany with robust mechanisms to improve their security attitudes and their resilience against cyberthreats.Read the original article: doi.org/10.13140/RG.2.2.12630.22082 

In this episode, Okey Ndibe and Emeka Onyeagwa interview Weyimi Lube, a social commentator and advocate for good governance in Nigeria. They discuss Weyimi's love for reading, especially books by Nigerian authors, and how it has shaped her political consciousness. Weyimi shares her experiences using her voice to advocate for change during political campaigns and the influence of her parents on her values and leadership style. She also discusses the importance of having a support system to navigate challenges. The conversation explores the experience of bigotry and division leading up to the election, the day of the election, the violence and intimidation faced, and the aftermath and reflection on the events. The conversation covers topics such as support from the diaspora, the impact of a CNN appearance, transitioning to a new name, and the speaker's education and experience at university. Weyimi B. Lube discusses her experiences with different Heads of Department (HODs) during her studies and the impact they had on her perspective. She shares her thoughts on Obi's presidency and how she believes he would have been accountable to the youth if he had won. Weyimi emphasizes the importance of problem-solving and the need for balance in leadership and followership. She also discusses the tendency to normalize abnormalities in Nigeria and the need for effective communication. Weyimi expresses her concerns about the economic crisis in Nigeria and the dire situation faced by the people. She highlights the passion and apathy of Nigerian youth and the lack of reasoning in Nigerian politics. Weyimi calls for young people's involvement in politics and discusses the potential future of Nigeria. The conversation covers various topics related to politics and society in Nigeria. It emphasizes the need for the Labor Party to be actively involved in society and address the concerns of the people. Peter Obi's intentionality and his engagement with youth and women are highlighted as positive aspects. The role of social media in spreading messages and the importance of education and sensitization are discussed. The conversation also emphasizes the need for unity and addressing personal issues. The interview concludes with a discussion on relaxation and hobbies, as well as reflections on the interview itself. ------------------- Chapters: 00:00 - Introduction and Background 02:27 - Love for Books and Reading 07:07 - Influence of Reading on Political Consciousness 13:27 - Basic Understanding of Politics 16:22 - Using Voice to Educate and Mobilize 32:34 - Navigating Relationships and Repercussions 38:42 - Unity and Love in Nigeria 43:36 - The 2023 Presidential and National Assembly Elections 44:25 - The Day of the Election 46:03 - Emotional Impact of the Election 50:26 - Violence and Intolerance 56:13 - The Importance of Love and Unity 59:58 - Support from the Diaspora 01:04:16 - Reflections on the Election 01:14:23 - Choosing to Get Active 01:17:16 - Bullying and Support from the Diaspora 01:18:16 - The Power of Social Media and Diaspora Support 01:19:13 - The Emotional Connection and Support from the Diaspora 01:20:12 - People Flying Back to Nigeria to Vote 01:21:10 - The Impact of the CNN Interview 01:23:30 - The Personal Experience of the CNN Interview 01:24:59 - The Effect of the CNN Interview on Social Media 01:25:58 - Choosing a Name and Maintaining Authenticity 01:27:26 - The Significance of the Name 'Orishawemi' 01:28:52 - The Decision to Start a Podcast and Making an Impact 01:30:49 - The Impact of CNN and Managing Expectations 01:33:17 - The Isolation and Challenges of University Life 01:35:10 - Education and Experience at Ogun State University 01:37:31 - The Importance of Speaking Yoruba in University 01:38:00 - The Unique Experience of Ibogun Campus 01:40:20 - Living in Close Proximity with Family 01:41:43 - The Challenges of Socializing in University 01:44:08 - The Importance of Critical Thinking in Engineering 01:48:02 - Accountability and Vision for a President 01:49:27 - The Accessibility and Relatability of Peter Obi 01:51:06 - The Ability to Provide Feedback to Peter Obi 01:54:06 - The Impact and Accessibility of Peter Obi 01:55:01 - The Experience of Gaslighting and Complaints 01:55:56 - Tolerance and Normalizing Abnormalities 01:56:54 - Lack of Balance in Leadership and Followership 01:57:24 - The Impact of Economic Crisis on Daily Life 01:58:21 - Calling Out Flaws and Propaganda 01:59:50 - The Importance of Constructive Criticism 02:00:49 - The Need for Progress and Change 02:01:19 - Economic Crisis as an Excuse 02:02:14 - The Struggle of Daily Life and Financial Burdens 02:03:13 - The Impact of Economic Crisis on Burials 02:04:05 - Rising Cost of Rice and Minimum Wage Disparity 02:05:02 - The Passion and Passionate-ness of Nigerians 02:05:30 - The Lack of Reason and Absence of Judgment 02:06:57 - The Importance of Education and Formation 02:07:26 - The Irrationality and Animalistic Drive in Nigeria 02:08:52 - The Decline in Living Standards 02:09:18 - The Need for Overhaul and Change 02:10:06 - Existential Crisis and the Concept of Change 02:11:01 - The Importance of Being Proactive for the Next Election Cycle 02:13:04 - The Cycle of Apathy and Entrenched Parties 02:14:29 - Addressing Ethnic Cleansing and Speaking Out 02:15:30 - The Love for Tolerating Abuse and the Need for Change 02:16:28 - The Importance of Education and Sensitization 02:20:44 - The Flaws of the Labour Party and the Need for Intentionality 02:22:41 - The Importance of Youth Dialogues and Engaging with the People 02:24:07 - The Role of Peter Obi and the Need for Continuous Engagement 02:25:36 - The Responsibility of the People to Educate and Unlearn 02:27:02 - The Need for Unity and Addressing Personal Issues 02:28:31 - Relaxation and Enjoyment of Cartoons and Music ----------------------------- Stay Connected: Follow "The Offside Musings Podcast" on Substack for insightful articles accompanying our episodes: offsidemusings.substack.com Listen to all episodes of "The Offside Musings Podcast" on your favorite podcast platforms. Social Media: YouTube: The Offside Musings Podcast Facebook: TheoffsideMusingsPodcast Instagram: @the_offside_musings Twitter: @MusingsOffside TikTok: @Theoffsidemusingspodcast --- Support this podcast: https://podcasters.spotify.com/pod/show/the-offside-musings/support

OH NO! IT'S COME BACK! The habits we develop and the neuropathways that get created by a disordered state of anxiety mean that even long into recovery, an anxious person might be re-triggered by life events, stress, memories, or any number of expected issues. This is normal. If this happens, we can feel things again ... anxiety, anxiety symptoms, and scary thoughts. This is not failure, or returning to square one, or "doing it wrong". This is being human and alive. But exactly what has been re-triggered when this happens? How does a recovered person or nearly recovered person become re-sensitized to anxious sensations and thoughts? This week we're talking about how external events can re-trigger INTERNAL sensitization - the state where we treat how we feel and what we think as urgently important or even dangerous. When suddenly re-sensitized, what then? As you might expect, this episode goes into detail about the process of de-sensitizing oneself to your internal state, which isn't a process at all. It's OK to be re-triggered. The trick here is to steer clear of the usual traps - looking for steps, tools, and techniques for making the feelings go away. When re-sensitized, the object of the game is to de-sensitize as you did before by allowing, accepting, tolerating, and surrendering. Bring it all with you, do not launch into evasive action or retreat rituals, and you will likely find that de-sensitization happens much more quickly than you expect it to. --- Want to pre-order Josh's book, “And How Does That Make You Feel?”  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://geni.us/JoshFletcher⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ---- If you love Disordered and think you might benefit from spending 30 full days in an everyday intensive small group recovery support group led by Josh and Drew,⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ check out Disordered Boost at https://disordered.fm/boost⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ ----- Want to ask us questions, share your wins, or get more information about Josh, Drew, and the Disordered podcast? Visit us on the web at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://disordered.fm⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Disclaimer: Disordered is not therapy or a replacement for therapy. Listening to Disordered does not create a therapeutic relationship between you and the hosts of the podcast. Information here is provided for psychoeducational purposes. As always, when you have questions about your well-being, please consult your mental health and/or medical care providers. If you are having a mental health crisis, always reach out immediately for in-person help.

Join us as we explore the interplay between feed forward and feedback in the somatosensory system. Learn how this impacts our ability to perform skilled movements and how our brain prepares for the next action. Find out how inhibition plays a crucial role in allowing us to venture forward in novel experiences. Check out DFX's learning journeys to build your clinicalreasoning skills with Tracy --> https://dfxlearningjourneys.thinkific.com/ Full transcription of our episode is available on ourwebsite. Timestamps:0:00:00 Introduction and revisiting the topic of praxis0:01:28 Difficulty of replicating human praxis in robots0:02:48 Somatosensory basis of dyspraxia0:05:01 Importance of enhancing somatosensation, movement, and vision0:05:41 The dynamic and solidified body map of the homunculus0:06:25 Purpose of somatosensory processing and sensory integrative processing0:07:49 Treating the whole, not just practicing the end products0:08:12 Understanding the homunculus and its dynamic nature0:10:04 Feed forward and feedback happening simultaneously0:11:35 Interplay between feed forward and feedback happening simultaneously in the brain0:12:22 Peripheral receptors learning in the neural network0:13:03 Neurodevelopmental changes in the peripheral and central nervous system0:13:45 Preparing the body for the next activity0:14:44 Sensitization of peripheral receptors in response to unexpected events0:16:12 Pre-emptive preparation of the brain in eye movement control0:17:19 Interplay between somatosensory, vestibular, and visual systems in response to uneven surfaces0:17:50 Importance of somatosensation as a perceptual layer that supports skilfulness0:18:58 The interplay between modulation and discrimination processing in novel experiences0:20:40 Treating the modulation issue to clear the slate for discrimination to become relevant0:21:57 Co-regulation through touch in discrimination processing0:22:25 The spreading activation of the homunculus enriching the body map0:23:10 The nervous system drawing somatosensory information to create inhibition and engagement0:23:41 The somatosensory system as the primary inhibitory system0:24:26 The whole process being somatosensory dependent0:24:42 The valence and tipping in the somatosensory system0:25:21 The role of the social engagement secretary in somatosensory modulation0:27:01 Co-regulation and the importance of a partner in somatosensory experiences0:29:20 The impact of not meeting a child's somatosensory needs on adaptation and efficiency0:29:54 The power of OT observations in shifting perceptions and supporting children's sensory needs0:34:20 The importance of separating modulation from discrimination in clinical reasoning for effective intervention0:34:54 The interplay between modulation, discrimination, cognition, and executive function in treatment. Connect with us: Instagram: https://www.instagram.com/spiritedconversations_ot/Facebook: https://www.facebook.com/spiritedconversationsOTYouTube: https://www.youtube.com/@spiritedconversations_OTWebsite: https://www.spiritedconversationspodcast.com/ Loved this episode and want an easy cost free way to support us?Subscribe to our youtube channel! Hosted on Acast. See acast.com/privacy for more information.

How can humanity use energetic communication and sensitization training to prepare us for whatever comes next? On this episode of The Science of Superpowers, Tonya Dawn Recla shares basic energetic communication concepts and explains the importance of the sensitization component. By integrating both constructs, we're able to learn how to align our communication at all levels and energetically express congruently. This opens us to awareness of how to activate and utilize our creative energy field and, ultimately, use our superpowers to change the world. Tap into these powerful episodes guaranteed to inspire a different perspective into a very different world.

How can humanity use energetic communication and sensitization training to prepare us for whatever comes next? On this episode of The Science of Superpowers, Tonya Dawn Recla shares basic energetic communication concepts and explains the importance of the sensitization component. By integrating both constructs, we're able to learn how to align our communication at all levels and energetically express congruently. This opens us to awareness of how to activate and utilize our creative energy field and, ultimately, use our superpowers to change the world. Tap into these powerful episodes guaranteed to inspire a different perspective into a very different world.

Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Investigating Fabrication, published by LoganStrohl on May 18, 2023 on LessWrong. Note 1: This was originally published in 2021. I'm now re-publishing it in 2023 as the penultimate post in The Nuts and Bolts Of Naturalism, as a demonstration of the method. I intend to publish a collection of much-more-complete demonstrations in the future, and I plan for them to explicitly discuss each step as I've described it in the sequence. For now, though, I hope that this partial demo will give you a taste of one way the overall process can go.(For a similarly partial demo by someone other than me, check out "Maps of Maps, and Empty Expectations" by Nora Ammann.) Note 2: This essay was written in response to “Lies, Damn Lies, and Fabricated Options”. I expect it'll be pretty confusing to read this one without having read that one first. However, I'm not the boss of you, and it isn't obvious to me anyway which reading order is best overall. If prolonged confusion makes you grumpy, I recommend reading Duncan's essay first. But if you try it backwards, I'd love to hear how that goes. 1. Motivation When I read Duncan's essay "Lies, Damn Lies, and Fabricated Options," it seemed to me to point toward something that's worth knowing for real, rather than just worth knowing about. I think it does a good job of helping the reader build a new concept that could conceivably be taken as a hypothesis in important situations. The hypothesis is, “Perhaps this thing that seems to me like an option isn't really a possibility, and it only seems like one because I'm in the grips of a map/territory conflation.” (Or, at least, “Perhaps the person I'm arguing with thinks their made-up option is real because [etc.].”) But I wasn't satisfied with my new concept “fabricated options”. There were some super important questions that I'd need to answer before I could put it to use. For instance, Which situations are the crucial ones for promoting this hypothesis to attention? How do I actually move my mind to recognize that the option I'm considering might be fabricated? Once I've posed the hypothesis, how do I confirm or deny it? When I've successfully identified a fabricated option, how can I prevent the usual harm? And, my favorite: How can I stop making this kind of mistake in the first place? So I set out to investigate option fabrication (the act), and what my brain is up to in the moments just before a fabricated option appears. I hoped that if I could learn where fabricated options come from, and what they are made of, I'd be a long way toward answering many of the practical questions on my list. 2. Approach I did naturalism to this. (One of the reasons this essay felt worth writing and sharing is to give people more chances to see what naturalism looks like in practice.) I assumed that there's sometimes A Thing Going On in my brain that in some ways resembles what Duncan called "fabricated options", and that my default understanding of the Thing is worse than I'd prefer. I set out to observe the Thing myself, directly and in real time, and to gradually build my own understanding of whatever I found. I tried to observe the Thing both in the "field" (as it occurs naturally in the course of daily life) and in the "lab" (as it occurs when I deliberately create controllable conditions that might give rise to it). This was not a full naturalist study (which usually takes at least a month), but was instead a "let's see what comes of a week or two" dalliance. Still, it turned out to follow the arc of a mostly complete study: Sensitization, zooming in, zooming out, and experimentation. [ETA: Though I used different terms here, these correspond to Locating Fulcrum Experiences, Getting Your Eyes On, Collection, and Experimentation.] 3. Lab Work, Part 1 In accordance with the “try it immediately” heuristic, I ...

My guest this episode is Lex Fridman, Ph.D., a Research Scientist at the Massachusetts Institute for Technology (MIT), an expert on artificial intelligence (AI) and robotics, and the host of the Lex Fridman Podcast. We discuss Lex's recent trip to the heart of the Ukrainian-Russian War, geopolitics, perspectives on people living in war zones, the shared human experience, and how information is communicated and controlled. As an experienced podcaster and public educator, Dr. Fridman offers unique insights into the art of holding conversations that grow understanding, especially when they involve people with opposing viewpoints. We also discuss the peer-review process for scientific research publications and how social media and podcasts are evolving the way science and technology are communicated. We consider how to find and follow your life's purpose, maintain ongoing motivation and implement support systems to build and sustain momentum. Our conversation also covers capitalism, masculinity, chess and cheating, Lex's idea for an AI robotics start-up and a Q&A from audience questions solicited on social media. As one of the main inspirations for the Huberman Lab podcast, hosting Dr. Fridman for this special centennial episode was an honor and a pleasure! Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/huberman Levels: https://levels.link/huberman Eight Sleep: https://www.eightsleep.com/huberman InsideTracker: https://www.insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Lex Fridman (00:04:30) LMNT, Levels, Eight Sleep (00:08:28) Podcasting (00:12:11) Ukraine, Russia, War & Geopolitics (00:23:17) Conflict & Generalized Hate (00:26:23) Typical Day in Ukraine; American Military & Information Wars (00:37:28) AG1 (Athletic Greens) (00:38:42) Deliberate Cold Exposure & Sauna; Fertility (00:46:44) Ukraine: Science, Infrastructure & Military; Zelensky (00:53:33) Firearms; Violence & Sensitization (00:57:40) MIT & Artificial Intelligence (AI), University Teaching & Pandemic (01:05:51) Publications & Peer Review, Research, Social Media (01:13:05) InsideTracker (01:14:17) Twitter & Social Media Mindset, Andrew Tate & Masculinity (01:26:05) Donald Trump & Anthony Fauci; Ideological Extremes (01:35:11) Biotechnology & Biopharma; Money & Status (01:45:08) Robotics, AI & Social Media; Start-ups (01:53:50) Motivation & Competition; Relationships (02:01:55) Jobs; A Career vs. A Calling; Robotics & Relationships (02:12:11) Chess, Poker & Cheating (02:22:25) Ideas of Lately (02:24:44) Why Lex Wears a Suit & Tie (02:27:50) Is There an AI Equivalent of Psychedelics?  (02:29:06) Hardest Jiu-Jitsu Belt to Achieve (02:32:07) Advice to Young People (02:39:29) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Neural Network Newsletter, Social Media Disclaimer Title Card Photo Credit: Mike Blabac

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Huberman Lab Podcast Notes Key Takeaways The human brain is shaped differently depending on sounds you are exposed to in utero and throughout the first years of brain developmentIt's probably best to skip the white noise machine to help your babies sleep – our brain is structured to hear environmental noises; constant white noise exposure may lead to delaysWhether you are right-handed or left-handed is strongly genetically determinedThe earlier, more intense, and longer you can have exposure to a second language – the better; human interaction allows for greater specialization of the languageMemory is widely distributed across the brain which is good because even in the event of head injury or illness requiring surgery, memory is generally preservedNew technologies are being studied to give paralyzed and nonverbal patients a chance to communicate again through the use of electrodes connected from the brain to a computer which uses AI to translateRead the full notes @ podcastnotes.orgMy guest is Eddie Chang, MD, a neurosurgeon and professor of neurological surgery at the University of California, San Francisco (UCSF) and the co-director of the Center for Neural Engineering & Prostheses. We discuss the brain mechanisms underlying speech, language learning and comprehension, communicating human emotion with words and hand gestures, bilingualism and language disorders, such as stuttering. Dr. Chang also explains his work developing and applying state-of-the-art technology to decode speech and using that information and artificial intelligence (AI) to successfully restore communication to patients who have suffered paralyzing injuries or “locked in syndrome.” We also discuss his work treating patients with epilepsy. Finally, we consider the future: how modern neuroscience is overturning textbook medical books, the impact of digital technology such as smartphones on language and the future of natural and computer-assisted human communication. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Levels: https://www.levelshealth.com/huberman Eight Sleep: https://www.eightsleep.com/huberman InsideTracker: https://insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Huberman Lab Premium https://hubermanlab.com/premium For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Eddie Chang, Speech & Language (00:03:00) Levels, Eight Sleep, InsideTracker, Momentous Supplements (00:07:19) Neuroplasticity, Learning of Speech & Environmental Sounds (00:13:10) White Noise Machines, Infant Sleep & Sensitization (00:17:26) Mapping Speech & Language in the Brain (00:24:26) Emotion; Anxiety & Epilepsy (00:30:19) Epilepsy, Medications & Neurosurgery (00:33:01) Ketogenic Diet & Epilepsy (00:34:56) AG1 (Athletic Greens) (00:36:10) Absence Seizures, Nocturnal Seizures & Other Seizure Types (00:41:08) Brain Areas for Speech & Language, Broca's & Wernicke's Areas, New Findings (00:53:23) Lateralization of Speech/Language & Handedness, Strokes (00:59:05) Bilingualism, Shared Language Circuits (01:01:18) Speech vs. Language, Signal Transduction from Ear to Brain (01:12:38) Shaping Breath: Larynx, Vocal Folds & Pharynx; Vocalizations (01:17:37) Mapping Language in the Brain (01:20:26) Plosives & Consonant Clusters; Learning Multiple Languages (01:25:07) Motor Patterns of Speech & Language (01:28:33) Reading & Writing; Dyslexia & Treatments (01:34:47) Evolution of Language (01:37:54) Stroke & Foreign Accent Syndrome (01:40:31) Auditory Memory, Long-Term Motor Memory (01:45:26) Paralysis, ALS, “Locked-In Syndrome” & Brain Computer Interface (BCI) (02:02:14) Neuralink, BCI, Superhuman Skills & Augmentation (02:10:21) Non-Verbal Communication, Facial Expressions, BCI & Avatars (02:17:35) Stutter, Anxiety & Treatment (02:22:55) Tools: Practices for Maintaining Calm Under Extreme Demands (02:31:10) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Huberman Lab Premium, Neural Network Newsletter, Social Media Title Card Photo Credit: Mike Blabac Disclaimer

My guest is Eddie Chang, MD, a neurosurgeon and professor of neurological surgery at the University of California, San Francisco (UCSF) and the co-director of the Center for Neural Engineering & Prostheses. We discuss the brain mechanisms underlying speech, language learning and comprehension, communicating human emotion with words and hand gestures, bilingualism and language disorders, such as stuttering. Dr. Chang also explains his work developing and applying state-of-the-art technology to decode speech and using that information and artificial intelligence (AI) to successfully restore communication to patients who have suffered paralyzing injuries or “locked in syndrome.” We also discuss his work treating patients with epilepsy. Finally, we consider the future: how modern neuroscience is overturning textbook medical books, the impact of digital technology such as smartphones on language and the future of natural and computer-assisted human communication. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman Levels: https://www.levelshealth.com/huberman Eight Sleep: https://www.eightsleep.com/huberman InsideTracker: https://insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman Huberman Lab Premium https://hubermanlab.com/premium For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Eddie Chang, Speech & Language (00:03:00) Levels, Eight Sleep, InsideTracker, Momentous Supplements (00:07:19) Neuroplasticity, Learning of Speech & Environmental Sounds (00:13:10) White Noise Machines, Infant Sleep & Sensitization (00:17:26) Mapping Speech & Language in the Brain (00:24:26) Emotion; Anxiety & Epilepsy (00:30:19) Epilepsy, Medications & Neurosurgery (00:33:01) Ketogenic Diet & Epilepsy (00:34:56) AG1 (Athletic Greens) (00:36:10) Absence Seizures, Nocturnal Seizures & Other Seizure Types (00:41:08) Brain Areas for Speech & Language, Broca's & Wernicke's Areas, New Findings (00:53:23) Lateralization of Speech/Language & Handedness, Strokes (00:59:05) Bilingualism, Shared Language Circuits (01:01:18) Speech vs. Language, Signal Transduction from Ear to Brain (01:12:38) Shaping Breath: Larynx, Vocal Folds & Pharynx; Vocalizations (01:17:37) Mapping Language in the Brain (01:20:26) Plosives & Consonant Clusters; Learning Multiple Languages (01:25:07) Motor Patterns of Speech & Language (01:28:33) Reading & Writing; Dyslexia & Treatments (01:34:47) Evolution of Language (01:37:54) Stroke & Foreign Accent Syndrome (01:40:31) Auditory Memory, Long-Term Motor Memory (01:45:26) Paralysis, ALS, “Locked-In Syndrome” & Brain Computer Interface (BCI) (02:02:14) Neuralink, BCI, Superhuman Skills & Augmentation (02:10:21) Non-Verbal Communication, Facial Expressions, BCI & Avatars (02:17:35) Stutter, Anxiety & Treatment (02:22:55) Tools: Practices for Maintaining Calm Under Extreme Demands (02:31:10) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Huberman Lab Premium, Neural Network Newsletter, Social Media Title Card Photo Credit: Mike Blabac Disclaimer

Many users' perceptions and perspectives are shaped by social media across multiple platforms, making it a dominant force in society. British-American Multi-Millarina Andrew Tate took over the algorithm, becoming polarizing among a social media generation that has become progressively sensitized to social media and algorithms.   This week, we break down Andrew Tate's de-platforming and analyze what lessons can be learned while examining how social media companies establish particular agendas and shape how society perceives issues and controversy.  

Intro Hyperplasia is different from hypertrophy in that the adaptive cell change in hypertrophy is an increase in the size of cells, whereas hyperplasia involves an increase in the number of cells. Body Hypertrophy seems to generally lead to hyperplasia Swimming pool analogy Hypertrophy for beginners, intermediate, advanced Common hypertrophy rep ranges Mechanical tension model Pure volume model Periodization changes what works best Sensitization to intensity, volume, etc Not just for bodybuilders Dietary considerations Lean gains vs “bulking” Blood flow restriction training - should we mention Conclusions Periodization!

Huberman Lab Podcast Notes Key Takeaways The inherent goal of the taste system is to get nutrients to survive – attracted to the ones we need, aversion to the ones that may kill usTaste is predetermined: parts of the brain will experience the full behavioral stimulus, even if activated when only ingesting water“I don't believe obesity is a disease of metabolism, I believe obesity is a disease of brain circuits.” – Dr. Charles ZukerSugar molecules activate the “gut-brain axis” which drives the preference for sugarArtificial sweeteners fail to curb the appetite for sugar because they work on the tongue to recognize sweetsness but do not activate sensors in the gut which satisfy the cravingDiseases of malnutrition today are linked to overnutrition (of processed foods), not the actual absence of foodHighly processed foods highjack the gut-brain axis, continuously reinforcing “wanting”Read the full notes @ podcastnotes.orgMy guest this episode is Dr. Charles Zuker, PhD, Professor of Biochemistry, Molecular Biophysics and Neuroscience at Colombia University and an Investigator with the Howard Hughes Medical Institute. Dr. Zuker is the world's leading expert in the biology of taste, thirst and craving. His laboratory explores the mechanisms of taste perception, focusing on how our conscious and unconscious processing of specific foods and nutrients guide our actions and behaviors. We discuss the neural circuits of taste, the “gut-brain axis,” the basis of food cravings and the key difference between wanting (craving) and liking (perceiving) sugar. We also explore how taste perception relates to specific food satiety, thirst, to our emotions, and expectation. We also consider how sugar containing and highly-processed foods can hijack the natural balance of the taste and digestive systems. Dr. Zuker provides a true masterclass in the biology of taste and perception that ought to be of interest to anyone curious about how the brain works, our motivated behaviors and the neural, chemical perceptual aspects of the mind. Thank you to our sponsors Thesis: https://takethesis.com/huberman ROKA: https://roka.com/huberman Helix Sleep: https://helixsleep.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Dr. Charles Zuker & Taste Perception (00:03:05) Momentous Supplements (00:04:35) Thesis, ROKA, Helix Sleep (00:08:35) Sensory Detection vs. Sensory Perception (00:11:48) Individual Variations within Perception, Color (00:16:20) Perceptions & Behaviors (00:20:19) The 5 Taste Modalities (00:26:18) Aversive Taste, Bitter Taste (00:28:00) Survival-Based & Evolutionary Reasons for Taste Modalities, Taste vs. Flavor (00:30:14) Additional Taste Modalities: Fat & Metallic Perception (00:34:02) Tongue “Taste Map,” Taste Buds & Taste Receptors  (00:39:34) Burning Your Tongue & Perception (00:42:54) The “Meaning” of Taste Stimuli, Sweet vs. Bitter, Valence (00:51:55) Positive vs. Negative Neuronal Activation & Behavior (00:56:16) Acquired Tastes, Conditioned Taste Aversion  (01:01:44) Olfaction (Smell) vs. Taste, Changing Tastes over One's Lifetime (01:09:14) Integration of Odor & Taste, Influence on Behavior & Emotion (01:17:26) Sensitization to Taste, Internal State Modulation, Salt (01:24:05) Taste & Saliva: The Absence of Taste (01:28:10) Sugar & Reward Pleasure Centers; Gut-Brain Axis, Anticipatory Response (01:36:23) Vagus Nerve (01:43:09) Insatiable Sugar Appetite, Liking vs. Wanting, Gut-Brain Axis (01:52:03) Tool: Sugar vs. Artificial Sweeteners, Curbing Appetite (01:54:06) Cravings & Gut-Brain Axis  (01:57:30) Nutrition, Gut-Brain Axis & Changes in Behavior (02:01:53) Fast vs. Slow Signaling & Reinforcement, Highly Processed Foods  (02:10:38) Favorite Foods: Enjoyment, Sensation & Context (02:15:58) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer

My guest this episode is Dr. Charles Zuker, PhD, Professor of Biochemistry, Molecular Biophysics and Neuroscience at Colombia University and an Investigator with the Howard Hughes Medical Institute. Dr. Zuker is the world's leading expert in the biology of taste, thirst and craving. His laboratory explores the mechanisms of taste perception, focusing on how our conscious and unconscious processing of specific foods and nutrients guide our actions and behaviors. We discuss the neural circuits of taste, the “gut-brain axis,” the basis of food cravings and the key difference between wanting (craving) and liking (perceiving) sugar. We also explore how taste perception relates to specific food satiety, thirst, to our emotions, and expectation. We also consider how sugar containing and highly-processed foods can hijack the natural balance of the taste and digestive systems. Dr. Zuker provides a true masterclass in the biology of taste and perception that ought to be of interest to anyone curious about how the brain works, our motivated behaviors and the neural, chemical perceptual aspects of the mind. Thank you to our sponsors Thesis: https://takethesis.com/huberman ROKA: https://roka.com/huberman Helix Sleep: https://helixsleep.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman. For the full show notes, visit hubermanlab.com. Timestamps (00:00:00) Dr. Charles Zuker & Taste Perception (00:03:05) Momentous Supplements (00:04:35) Thesis, ROKA, Helix Sleep (00:08:35) Sensory Detection vs. Sensory Perception (00:11:48) Individual Variations within Perception, Color (00:16:20) Perceptions & Behaviors (00:20:19) The 5 Taste Modalities (00:26:18) Aversive Taste, Bitter Taste (00:28:00) Survival-Based & Evolutionary Reasons for Taste Modalities, Taste vs. Flavor (00:30:14) Additional Taste Modalities: Fat & Metallic Perception (00:34:02) Tongue “Taste Map,” Taste Buds & Taste Receptors  (00:39:34) Burning Your Tongue & Perception (00:42:54) The “Meaning” of Taste Stimuli, Sweet vs. Bitter, Valence (00:51:55) Positive vs. Negative Neuronal Activation & Behavior (00:56:16) Acquired Tastes, Conditioned Taste Aversion  (01:01:44) Olfaction (Smell) vs. Taste, Changing Tastes over One's Lifetime (01:09:14) Integration of Odor & Taste, Influence on Behavior & Emotion (01:17:26) Sensitization to Taste, Internal State Modulation, Salt (01:24:05) Taste & Saliva: The Absence of Taste (01:28:10) Sugar & Reward Pleasure Centers; Gut-Brain Axis, Anticipatory Response (01:36:23) Vagus Nerve (01:43:09) Insatiable Sugar Appetite, Liking vs. Wanting, Gut-Brain Axis (01:52:03) Tool: Sugar vs. Artificial Sweeteners, Curbing Appetite (01:54:06) Cravings & Gut-Brain Axis  (01:57:30) Nutrition, Gut-Brain Axis & Changes in Behavior (02:01:53) Fast vs. Slow Signaling & Reinforcement, Highly Processed Foods  (02:10:38) Favorite Foods: Enjoyment, Sensation & Context (02:15:58) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Instagram, Twitter, Neural Network Newsletter Title Card Photo Credit: Mike Blabac Disclaimer

Join us for the third and final episode of our series on the progress of the Sensitization in Transplantation: Assessment of Risk (STAR) workgroup. Dr. Michelle Hickey joins us to discuss perhaps the newest and most controversial STAR workgroup sub-study, non-HLA antibody testing and diagnostics.

In this episode of RCA Radio, host Brandon Miller is joined by Dr. Matthew Jorgensen and Audrey Turley, Matt a board-certified toxicologist with a Ph.D. in chemistry and is Nelson Laboratory's Chemistry and Materials Scientist and Audrey is a Nelson Labs Senior Biocompatibility Expert.Listen in as Matt and Audrey help educate our listers about Irritation and Sensitization in medical devices biocompatibility for launching your products in this part of the Intro into Biocompatblity podcast series.About RCARegulatory Compliance Associates® (RCA) provides worldwide services to the following industries for resolution of compliance and regulatory challenges:Pharmaceutical Biologic & BiotechnologySterile compoundingMedical deviceWe understand the complexities of running a life science business and possess areas of expertise that include every facet of R&D, operations, regulatory affairs, quality, and manufacturing. We are used to working on the front lines and thriving in the scrutiny of FDA-and globally-regulated companies.As your partners, we can negotiate the potential minefield of regulatory, compliance, quality, and private equity due diligence with insight, hindsight, and the clear advantage of our unique expertise and experience.About Nelson LabsEvery year, hundreds of medical device, pharmaceutical, and tissue companies make Nelson Labs their testing laboratory of choice. For them, the decision is easy. Nelson Labs is a clear leader in the microbiology and analytical chemistry testing industry, offering more than 800 laboratory tests and employing more than 500 scientists and staff in state-of-the-art facilities. We are known for exceptional quality and rigorous testing standards, but it is our focus on the bigger picture that sets us apart. We look beyond test results and partner with you to achieve your long-term business goals — mitigating risk, being first to market, and succeeding with your customers.Companies choose Nelson Labs for our:Thought leaders and approachable experts. We give you direct access to industry authorities who understand your business and add value every step of the way.Customer-centric culture. We take the time to understand your vision. Your goals become our goals.Real-time project management tools and a dedicated client portal. We provide proactive information, keeping you informed and in control.Metric-driven testing processes. We're our own toughest customer, holding ourselves to goals exceeding 99% for things that matter most to you, like quality, turnaround time, and testing accuracy.Global compliance expertise and support. We act as a trusted advisor, helping you navigate the ever-changing compliance landscape.See how we can help you mitigate risk, be first to market, and succeed with your customers.

When it comes to the topic of porn, one of the most common questions is whether or not it can actually be addictive. According to many addiction experts, it absolutely can be.Click here to access the resources discussed in this episode.To learn more about the harms of pornography on consumers, relationships, and its larger societal impacts, visit FTND.org.To support this podcast, click here.As you go about your day we invite you to increase your self-awareness, look both ways, check your blindspots, and consider before consuming.Fight the New Drug collaborates with a variety of qualified organizations and individuals with varying personal beliefs, affiliations, and political persuasions. As FTND is a non-religious and non-legislative organization, the personal beliefs, affiliations, and persuasions of any of our team members or of those we collaborate with do not reflect or impact the mission of Fight the New Drug.

This week, we're back in the flow of the Amidah exploring the 4th and 5th middle weekday blessings. We talk timeless personal Passover stories, S&H green stamps, healing vs cure, and being in the body. There's also lots of inter-text, lots of liturgical variation, and lots of questions to be had. Support us on ko-fi! Membership tiers are now live. There are fun perks to be had! To support the show without perks, you can make a tax-deductible donation here. And please rate, subscribe, and share! It means the world to us, and we are so grateful. Thank you! Be sure to check out this week's Transcript And show notes And follow us on facebook and instagram @thelight.lab

Join us for the second episode of our series on the progress of the Sensitization in Transplantation: Assessment of Risk (STAR) workgroup. During this second episode of the STAR workgroup series we are joined by Dr. David Pinelli for a discussion on alloimmunity and diagnostics.

Drs Russo and Horvath discuss the 2021 Dan Mishell article award winner The concentration of fetal red blood cells in first-trimester pregnant women undergoing uterine aspiration is below the calculated threshold for Rh sensitization by Horvath et al.  

Join us for the first in a multi-episode series on the progress of the Sensitization in Transplantation: Assessment of Risk (STAR) workgroup. In the first episode of the STAR workgroup series, we discuss progress in the utility of anti-HLA antibody testing in clinical trials with Dr. Nicole Valenzuela.

The Dr. Junkie show does not offer medical advice. In this episode I take another shot at describing how cocaine works in the body. I talk about where it comes from and how it's produced, why it is so extreme in its effects, and how we can regulate and decriminalize it to put all illegal drug dealers out of business overnight. Plus, I discuss sleep cycles and why they are so important, Sigmund Freud's dark outlook on life and why we can thank cocaine for his conclusions, what happens when we mix cocaine and alcohol.For more on sleep, check out Dr. Matthew Walker's book, Why We Sleep.For more on the history of coca farming, cocaine production, cocaine addiction, and all sorts of other stuff, check out my book, Dr. Junkie: One Man's Story of Addiction and Crime that will Challenge Everything you know about the War on Drugs. The Dr. Junkie Show  was recently listed in Feedspot's top 10 podcasts about drugs.  

In this episode, I take you along on my first experience of injecting heroin. Rituals of use are a big part of addiction. They have increasingly become the focus of both  addiction researchers and treatment providers. When we do something that makes us feel better (take a drug, place a bet, make a move, hit the gas, take a trip, etc.), we begin to feel the effects of that action before we actually do it. And the more we do it, the earlier and more intense our feelings become. Injecting drugs is a ritual of use. We lay out the equipment in a familiar room, on a  familiar table. We turn on the same TV or we click on the same stereo. We notice the same sounds and smells, the same sense of what is coming. All of it becomes part of the ritual.  In cultures of drug prohibition, rituals of use expand to fill an addicted person's entire life. Our laws are designed to make it appear to be the fault of drug users, not the culture which ensured it will happen.  Audio for the intro & outro came from a 1967 anti-drug PSA called Narcotics: Pit of Despair. 

I have recently received so many questions about the book that I thought I would spend an episode talking about it. Dr. Junkie: One Man's Story of Addiction and Crime that will Challenge Everything you Know about the War on Drugs is available on Amazon and Barnes & Nobel. This autobiographical account of addiction and crime in the United States reveals the design-flaws of the current War on Drugs, which has consistently failed to focus on the things citizens should want prioritized, like saving lives, reducing addiction and getting rid of dangerous street drugs. Instead, the we have spent trillions of dollars imprisoning our neighbors, killing our family-members and driving the price of these chemicals sky high. And if we have learned nothing else through the 120 years plus of this worthless war, it is that  people will not be stopped from using drugs, no matter how dangerous, expensive or illegal they are. Dr. Junkie is a story about how we can change our priorities and save lives. We are currently in the midst of the worst overdose crisis in contemporary history, and it can only be stopped with safe supply, therapy, support, treatment...in a word, love.  If we truly want people to stop, and to experience minimal damage from their use, we would legalize all drugs and, as a bonus, put all illegal drug dealers out of business overnight. 

Hello and Welcome everyone to episode #5! Today I am going to talk about another part of pain reprocessing therapy - Emotional Awareness and Expression therapy Let me first briefly summarize the main teaching points of prior 4 episodes  Fibromyalgia pain – neuroplastic pain - misfiring neurons in the brain pain centers and pain pathways. They are misinterpreting safe or neutral signals from the body. THE PAIN IS REAL. The good news is that the pain pathways CAN BE REWIRED and the pain reversed. Other names for neuroplastic pain are central SENSITIZATION or AUGMENTATION pain. Reasons for pain: unprocessed emotions, prior traumatic experiences in life, exacerbated by current trauma or injuries. Winning at fibromyalgia process – my unique method implemented in treatment of my patients with fibromyalgia that borrows from several fields. The principal parts of the process are: Confirm the diagnosis of fibromyalgia (best handled by a Rheumatologist), 2. Education about the neuroplastic pain and Being open to the diagnosis/the concept of neuroplastic pain, and Willingness to Try the methods PRT (pain reprocessing therapy). Of those we talked about A) the practice of fierce self-compassion which combines mindfulness, identifying our emotions and giving ourselves love and compassion like we would do for other people. B) somatic tracking which consists of approaching your pain with curiosity and basically “scanning” your body for all the sensations you feel in the moment and instead of being annoyed or upset, you send safety messages to your brain such as “I am ok, brain, I am healthy and strong, it will be ok”. The purpose of that is to soothe the brain and reassure it like you would reassure a scared small child. Today I will talk about a psychological therapy referred to as emotional awareness and expression therapy (EAET). It is SOMEWHAT new approach but HAS been studied with SUCCESS in patients with fibromyalgia. Some case studies even suggest it can lead to RESOLUTION or REMISSION of the pain in some people! This is why I am so excited about this technique and have started using it in my practice in selected patients in whom I deemed it safe to proceed. We already touched upon how the stress and emotions from the stress, can trigger, worsen or maintain our pain. Focus of EAET is the trauma, stress and relationship problems found in many people with chronic pain. Even more precisely, it focuses on thoughts and feelings. So how does it work? It is done in individual or group sessions, anywhere from 8-12 sessions. After educating my patients about the role of stress and emotions in their pain, we talk about the traumas or conflicts in their lives that appear to drive their pain. Some patients have told me upon initial discussion that they did not have any repressed emotions or no past trauma. As we start talking more, it turns out they have been through so much emotional pain and charged experiences, but they just did not associate them with their physical pain. We talk about it and I ask them to express emotionsthey have been avoiding or blocking related to the trauma or stressors, especially anger, but also guilt, sadness, love and self-compassion. Because EAET is rather new, there are few providers who have been trained specifically to deliver it. Many psychologists and other mental health providers have training in trauma-focused therapies and "exposure-based" therapies that help patients overcome their fears. I am part of the pain reprocessing therapy course led by Dr. Schubiner who is one of the leading minds in the field of chronic pain and utilization of pain reprocessing therapy. He shares with us many successful stories and demonstrations of this techniques in his practice, the success and often immediate improvement is astounding. A Therapist has patients revisit important conflicts or traumatic experiences that involve other people and helps patients "express the unexpressed" feelings to those people. This can be done with writing exercises but also involves "talking to" an empty chair where the imagined other person sits. Patients are encouraged to activate and express their emotions fully, using their words, voice tone, and bodily expression (arms, face). Patients are helped to express the full range of avoided emotionsThey usually go through a range of emotions with guilt following anger, then sadness. Then they are guided by a therapist to love and self-compassion. This is all done with just imagining the other person. Finally, patients are encouraged to plan and role play how they would like to be in real life with people who have been a source of stress or conflict. Such communication depends on the type of relationship and may involve healthy assertiveness and setting boundaries, and often includes being open, vulnerable, and expressing intimacy. Throughout therapy, patients are encouraged to work on emotional awareness, writing exercises, emotional expression, and healthy communication as homework. Successful EAET is typically associated with substantial reductions or even elimination of pain as well as improvements in functioning, mood, and relationships. EAET and related approaches are associated with greater risk than CBT and other psychological treatments for chronic pain. EAET encourages patients to disclose and emotionally express experiences and feelings that may have been avoided for many years and that often are quite upsetting. It is not uncommon, therefore, for patients to become temporarily more upset (e.g., anxious, depressed, angry) as they start to deal with memories and feelings that have long been avoided. Pain and other physical symptoms sometimes increase temporarily. Because patients are encouraged to communicate and interact differently in their relationships, these relationships might change in ways that are unexpected. Practitioners of EAET believe, however, that such emotional and relationship changes are important to make, and even though they may be difficult in the short run, such changes can be healthy and lead to pain reductions in the longer-term. EAET may not be appropriate for certain patients, especially those who have difficulties regulating their emotions, who have trouble thinking when they are emotional, or who tend to hurt themselves or others when memories or feelings are activated or intense. This would be all assessed during early sessions and decisions would be made how to best proceed. That's it for today's session. Please share or leave a review if you found it helpful. I would really appreciate it. In the next episode, we will start tying all of these individual parts I have spoken about so far, together. A Winning at fibromyalgia approach is slowly emerging  Until next time 