Podcasts about igf1

Stew tears into the latest attempt by Turning Point USA proxies to push a dubious alibi for Erika Kirk regarding the day of Charlie Kirk's assassination. Exposing the gaping holes, suspicious retractions, and corporate media cover-ups.   Join us on KICK https://kick.com/stewpeters   Get your first month for just $5 and join the movement before the fake election season heats up. Unlock exclusive content, behind-the-scenes access, and a community that refuses to be silenced. Join Today: https://StewPeters.tv   Support the network

In this explosive episode of God Grit & Glory, Stew joins the show as a featured guest to pull back the curtain on the high stakes battle between uncompromising truth and corporate silence. Facing a high-pressure ultimatum from major sponsors keep quiet or lose millions.   Join us on KICK https://kick.com/stewpeters   Get your first month for just $5 and join the movement before the fake election season heats up. Unlock exclusive content, behind-the-scenes access, and a community that refuses to be silenced. Join Today: https://StewPeters.tv   Support the network

Stew dismantles the narrative surrounding Charlie Kirk's assassination, exposing controlled opposition and federal assets pushing fabricated evidence.   Stew sits down with Diligent Denizen to unpack damning new evidence that completely shatters the official timeline in the Charlie Kirk assassination case. From weaponized lavalier mics to a hidden restaurant receipt 200 miles away from the crime scene.   Join us on KICK https://kick.com/stewpeters   Get your first month for just $5 and join the movement before the fake election season heats up. Unlock exclusive content, behind-the-scenes access, and a community that refuses to be silenced. Join Today: https://StewPeters.tv   Support the network

Stew exposed the state-backed propagandists and fake-news "feds" who have infiltrated conservative spaces directly from the halls of the Pentagon. From manufactured X beefs to coordinate cover-ups, Stew sits down with former Charlie Kirk cameraman Mitchell Manley also known as "Artifex Memoriarum" on X to uncover shocking allegations regarding Turning Point USA and its connection to federal handlers.   Join us on KICK https://kick.com/stewpeters   Get your first month for just $5 and join the movement before the fake election season heats up. Unlock exclusive content, behind-the-scenes access, and a community that refuses to be silenced. Join Today: https://StewPeters.tv   Support the network

Andrew Wilson promised undeniable receipts that would shut down the questions surrounding Charlie Kirk's death—but what he released raises even more questions. Stew tears into the alleged messages, the security claims, and the contradictions surrounding the official story. Dan Bilzerian joins Stew to break down the shocking vote-count discrepancy he says occurred during his Florida 6 congressional race, including the sudden shift of roughly 2,000 votes and the unanswered questions surrounding the count.   Join us on KICK https://kick.com/stewpeters   Get your first month for just $5 and join the movement before the fake election season heats up. Unlock exclusive content, behind-the-scenes access, and a community that refuses to be silenced. Join Today: https://StewPeters.tv   Support the network

Two of the most relentless voices fighting for truth are joining forces for an unscripted, no-holds-barred showdown against the censorship regime. Join us now live on KICK https://kick.com/stewpeters Get your first month for just $5 and join the movement before the fake election season heats up. Unlock exclusive content, behind-the-scenes access, and a community that refuses to be silenced. Join Today: https://StewPeters.tv Support the network

The prosecution says Tyler Robinson was a terrible shot—but somehow wants the public to believe he pulled off an impossibly precise rooftop shooting in a matter of seconds. Stew breaks down the contradictions surrounding the rifle, the disputed screwdriver evidence, the prosecution's mounting assumptions, and the legal arguments now putting the entire case under a microscope. Anna Escobar joins Stew to dig into a disturbing trail of Google searches, private flights, FBI connections, and the mysterious rise of Jacqueline McGuire's crisis PR firm. The data raises explosive questions about Turning Point, Las Vegas, and whether these connections are really coincidence—or evidence of a much bigger operation. J.D. Sharp joins Stew for a wide-ranging discussion on escalating tensions in the Middle East, concerns over military readiness, global trade chokepoints, and the growing distrust many Americans feel toward political institutions. From foreign policy and energy security to the future of American power, this conversation explores the narratives, fears, and unanswered questions shaping today's geopolitical landscape. Join us now live on KICK https://kick.com/stewpeters Get your first month for just $5 and join the movement before the fake election season heats up. Unlock exclusive content, behind-the-scenes access, and a community that refuses to be silenced. Join Today: https://StewPeters.tv Support the network

Owen Benjamin joins Stew to expose the latest political headlines involving Charlie Kirk and Nick Fuentes. He pulls back the curtain on the entertainment industry, sharing raw insights into what it really takes to survive being blacklisted by Hollywood.   Join us on KICK https://kick.com/stewpeters Get your first month for just $5 and join the movement before the fake election season heats up. Unlock exclusive content, behind-the-scenes access, and a community that refuses to be silenced. Join Today: https://StewPeters.tv   Support the network

Blake Nef says he remembers some things about Charlie Kirk's final day but suddenly the details become remarkably unclear when the questions turn to his own whereabouts. Stew breaks down the timeline and asks why these basic questions remain unanswered. John Cullen joins Stew to break down the aircraft and drone activity surrounding the Charlie Kirk shooting and the open source flight data that Cullen says raises massive questions about what was happening in the sky. Anna Escobar Joins Stew to break down crucial flight-tracking logs, geofencing routes, and suspicious Google Trends activity directly originating from military facilities during key windows of interest. We trace how these high-altitude Hades aircraft and coordinated military procurement efforts tie directly into broader patterns that the mainstream system refuses to investigate.   Join us on KICK https://kick.com/stewpeters Get your first month for just $5 and join the movement before the fake election season heats up. Unlock exclusive content, behind-the-scenes access, and a community that refuses to be silenced. Join Today: https://StewPeters.tv   Support the network

Andy Loue joins Stew to expose the bizarre flight patterns of military aircraft surrounding the Charlie Kirk assassination and Tyler Robinson's reported surrender. The timestamps, altitude changes, and suspicious movements raise questions that the establishment desperately wants you to stop asking. Keli Rabon joins Stew to expose the unanswered questions surrounding the screwdriver, the rifle, the rooftop, and the evidence being used to build the case against Tyler Robinson.   Join us on KICK https://kick.com/stewpeters Get your first month for just $5 and join the movement before the fake election season heats up. Unlock exclusive content, behind-the-scenes access, and a community that refuses to be silenced. Join Today: https://StewPeters.tv   Support the network

Stew joins The Black Line Brief for a deep dive into the Charlie Kirk assassination, questioning the official lone-gunman narrative and examining the motives, inconsistencies, and evidence surrounding the case. They explore Charlie Kirk's reported political shift, the power networks surrounding Turning Point USA, and the growing push for independent, crowd-sourced investigation.   Join us on KICK https://kick.com/stewpeters Get your first month for just $5 and join the movement before the fake election season heats up. Unlock exclusive content, behind-the-scenes access, and a community that refuses to be silenced. Join Today: https://StewPeters.tv   Support the network

Matt Tucciarone joins Stew to expose the explosive allegations on TPUSA about the organization's internal culture, political power structure, and what he says he witnessed behind the scenes. Jimmy Dore joins Stew to confront the questions surrounding vaccine injuries, COVID mandates, censorship, Fauci, and the media's handling of dissent and also examine the unanswered questions and allegations surrounding Charlie Kirk's assassination without accepting the establishment narrative at face value. Octavia LaVon joins Stew to break down Tyler Robinson's defense brief and explains why its confusing language has led many people to believe the defense conceded key facts in the case. Peptides are exploding in popularity, but do you really know what you're putting into your body? Dino Guglielmelli joins Stew to expose the importance of potency, purity, sourcing, testing, microdosing, and the claims surrounding peptides for longevity, inflammation, brain health, hormones, and overall wellness.   Join us on KICK https://kick.com/stewpeters Get your first month for just $5 and join the movement before the fake election season heats up. Unlock exclusive content, behind-the-scenes access, and a community that refuses to be silenced. Join Today: https://StewPeters.tv   Support the network

Rob McCoy is suddenly explaining his whereabouts, international travel, and connections after explosive questions surrounding the Charlie Kirk investigation. Ana Escobar joins Stew to dissect the timeline, the alleged alibi, the Israel connections, and the disturbing network of unanswered questions that refuse to go away. Get your first month for just $5 and join the movement before the fake election season heats up. Unlock exclusive content, behind-the-scenes access, and a community that refuses to be silenced. Join Today: https://StewPeters.tv   Support the network

Ana Escobar joins Stew Peters with explosive new findings involving Cliff Sims, Fort Huachuca, and search activity in the days and weeks surrounding Charlie Kirk's assassination. John Jubilee joins Stew to expose the approach behind his stunning 88-day transformation—from “dad bod” to a dramatically leaner, stronger physique without spending hours in the gym. Jubilee explains the Energized Health philosophy of cellular hydration, lean muscle, and total-body wellness while sharing powerful client transformation stories.   Join us now live on KICK https://kick.com/stewpeters Get your first month for just $5 and join the movement before the fake election season heats up. Unlock exclusive content, behind-the-scenes access, and a community that refuses to be silenced. Join Today: https://StewPeters.tv   Support the network

Ana Escobar joins Stew Peters to expose a disturbing flight trail involving Turning Point USA-linked jets, Hanscom Field, and other obscure airfields as she investigates a potential weapons-smuggling network.   Join us now live on KICK https://kick.com/stewpeters Get your first month for just $5 and join the movement before the fake election season heats up. Unlock exclusive content, behind-the-scenes access, and a community that refuses to be silenced. Join Today: https://StewPeters.tv   Support the network

This week on the Stew Peters Network, we break down the investigations, interviews, and major stories that generated the biggest questions and the strongest reactions. From forensic analysis and security failures to government accountability and headline-making developments, here's your complete weekly recap of the stories everyone is talking about.   John Jubilee is exposing the catastrophic truth about these GLP-1 shots causing blindness, pancreatitis, and muscle loss. I went from inflamed and fat to shredded with real cellular hydration through Energized Health — ditch the dangerous drugs and transform your body the right way. Get your first month for just $5 and join the movement before the fake election season heats up. Unlock exclusive content, behind-the-scenes access, and a community that refuses to be silenced. Join Today: https://StewPeters.tv   Support the network

Join us now live on KICK https://kick.com/stewpeters Get your first month for just $5 and join the movement before the fake election season heats up. Unlock exclusive content, behind-the-scenes access, and a community that refuses to be silenced. Join Today: https://StewPeters.tv Support the network

Join us on KICK, the EXCLUSIVE home of Stew's daily livestream broadcasts! https://kick.com/stewpeters Get your first month for just $5 and join the movement before the fake election season heats up. Unlock exclusive content, behind-the-scenes access, and a community that refuses to be silenced. Join Today: https://StewPeters.tv Support the network

OVERWHELMING, Irrefutable evidence that can't be explained away directly connects Israel to the murder of Charlie Kirk. Ana Escobar joins Stew to present the hard data, which will inevitably be deleted immediately after it's exposed!   Haydn Wood joins Stew to break down the "evidence" used by the prosecution, specifically the video(s) of "Tyler Robinson's" movements around campus at UVU on Sept 10, 2025. Get your first month for just $5 and join the movement before the fake election season heats up. Unlock exclusive content, behind-the-scenes access, and a community that refuses to be silenced. Join Today: https://StewPeters.tv   Support the network

This month brought a relentless barrage of explosive cover-ups, deep-state collusion, and critical revelations that the regime's fake-news apparatus refuses to touch. From exposing the hidden Fort Huachuca timelines and tearing down the fraudulent narratives surrounding high-profile assassinations to blowing the lid off NDAA provisions forcing foreign technology into American military hardware, we've tracked every single betrayal they tried to hide from you. This monthly recap delivers an aggressive, line-by-line breakdown of uncensored interviews, courtroom scrambling, rampant censors taking down independent voices, and the treacherous globalist agendas actively dismantling our nation. Catch up on every single bombshell report, exclusive investigation, and live exposé you missed this month—uncensored, uncompromising, and absolutely unapologetic. Celebrate freedom while we still have it. Become an annual member of the Stew Peters Locals community and receive $17 OFF for a limited time. Your membership includes: • Exclusive members-only content • Live chats and community discussions • Behind-the-scenes access • Directly supporting independent, uncensored journalism. Don't wait, his special ends July 31.

This month brought a relentless barrage of explosive cover-ups, deep-state collusion, and critical revelations that the regime's fake-news apparatus refuses to touch. From exposing the hidden Fort Huachuca timelines and tearing down the fraudulent narratives surrounding high-profile assassinations to blowing the lid off NDAA provisions forcing foreign technology into American military hardware, we've tracked every single betrayal they tried to hide from you. This monthly recap delivers an aggressive, line-by-line breakdown of uncensored interviews, courtroom scrambling, rampant censors taking down independent voices, and the treacherous globalist agendas actively dismantling our nation. Catch up on every single bombshell report, exclusive investigation, and live exposé you missed this month—uncensored, uncompromising, and absolutely unapologetic. Celebrate freedom while we still have it. Become an annual member of the Stew Peters Locals community and receive $17 OFF for a limited time. Your membership includes: • Exclusive members-only content • Live chats and community discussions • Behind-the-scenes access • Directly supporting independent, uncensored journalism. Don't wait, his special ends July 31.

Celebrate freedom while we still have it. Become an annual member of the Stew Peters Locals community and receive $17 OFF for a limited time. Your membership includes: • Exclusive members-only content • Live chats and community discussions • Behind-the-scenes access • Directly supporting independent, uncensored journalism. Don't wait, his special ends July 31.

The Leah Files joins Stew to take a deeper look into what made TPUSA the billion dollar organization they've become. Celebrate freedom while we still have it. Become an annual member of the Stew Peters Locals community and receive $17 OFF for a limited time. Your membership includes: • Exclusive members-only content • Live chats and community discussions • Behind-the-scenes access • Directly supporting independent, uncensored journalism. Don't wait, his special ends July 31.

Celebrate freedom while we still have it. Become an annual member of the Stew Peters Locals community and receive $17 OFF for a limited time. Your membership includes: • Exclusive members-only content • Live chats and community discussions • Behind-the-scenes access • Directly supporting independent, uncensored journalism. Don't wait, his special ends July 31.

Celebrate freedom while we still have it. Become an annual member of the Stew Peters Locals community and receive $17 OFF for a limited time. Your membership includes: • Exclusive members-only content • Live chats and community discussions • Behind-the-scenes access • Directly supporting independent, uncensored journalism. Don't wait, his special ends July 31.

The fake news media and the uniparty puppets thought they could bury the truth, but we aren't letting them off the hook. This month, we tore down their propaganda machine—exposing the corrupt courts, the explosive developments in the Charlie Kirk investigation and Tyler Robinson trial, the endless military-industrial complex spending through the NDAA, and the treasonous globalist agenda destroying our nation from within. Celebrate freedom while we still have it. Become an annual member of the Stew Peters Locals community and receive $17 OFF for a limited time. Your membership includes: • Exclusive members-only content • Live chats and community discussions • Behind-the-scenes access • Directly supporting independent, uncensored journalism. Don't wait, his special ends July 31.

The occupied United States Government, made up of actors willing to read their lines from the Zionist script are overtly merging the US Military, intel, weapons and secrets with "Israel", the FAKE, terrorist "nation state" in the Middle East. Celebrate freedom while we still have it. Become an annual member of the Stew Peters Locals community and receive $17 OFF for a limited time. Your membership includes: • Exclusive members-only content • Live chats and community discussions • Behind-the-scenes access • Directly supporting independent, uncensored journalism. Don't wait, his special ends July 31.

Celebrate freedom while we still have it. Become an annual member of the Stew Peters Locals community and receive $17 OFF for a limited time. Your membership includes: • Exclusive members-only content • Live chats and community discussions • Behind-the-scenes access • Directly supporting independent, uncensored journalism. Don't wait, his special ends July 31.

LIVE BROADCAST: Iran War, Charlie Kirk, Rick Cutler, the SUV, the dirt from UVU Your Calls tonight! 507-698-STEW (7839) Celebrate freedom while we still have it. Become an annual member of the Stew Peters Locals community and receive $17 OFF for a limited time. Your membership includes: • Exclusive members-only content • Live chats and community discussions • Behind-the-scenes access • Directly supporting independent, uncensored journalism. Don't wait, his special ends July 31.

Stew Peters LIVE CALL-IN SHOW: Call NOW 507-698-STEW to discuss war with Iran, China/Cuba scripted narrative, Charlie Kirk's murder and the occupation force behind all of it. Celebrate freedom while we still have it. Become an annual member of the Stew Peters Locals community and receive $17 OFF for a limited time. Your membership includes: • Exclusive members-only content • Live chats and community discussions • Behind-the-scenes access • Directly supporting independent, uncensored journalism. Don't wait, his special ends July 31.

The PERFECT procurement pipeline was exposed on The Stew Peters Show when Ana Escobar revealed a damning bank of Google Image Searches that originated from Fort Huachuca. The fallout has been eye-popping! Turning Point USA Insider Mitchell Manley, who worked closely with Charlie Kirk beginning as a young teenager, joins the Stew Peters Show to break his silence, name names and dismantle the web of lies being told about who Charlie Kirk was, why he was killed and who was involved. John Jubilee is exposing the catastrophic truth about these GLP-1 shots causing blindness, pancreatitis, and muscle loss. I went from inflamed and fat to shredded with real cellular hydration through Energized Health — ditch the dangerous drugs and transform your body the right way. Celebrate freedom while we still have it. Become an annual member of the Stew Peters Locals community and receive $17 OFF for a limited time. Your membership includes: • Exclusive members-only content • Live chats and community discussions • Behind-the-scenes access • Directly supporting independent, uncensored journalism. Don't wait, his special ends July 31.

Explore how IGF-1, saturated fat, and keto diets can fuel cancer growth, while plant-based diets offer protection. #CancerRisk #KetoMyths #IGF1 #PlantProtection

Dr. Deb Muth 0:00 Welcome back to Let’s Talk Wellness Now. I’m your host, Dr. Zab, and we are continuing our discussion this week on 0:08 peptides. And so, if you haven’t heard our first conversation about peptides, 0:13 please go back and look at that episode. We talk all about the manufacturing, the safety, the quality of peptides, and we 0:20 dove into GLP1s. And today we’re going to dive into peptides for sexual 0:26 wellness, immune function, growth hormone, and all the amazing fun things 0:32 we can do with peptides. So, as usual, grab your cup of coffee or tea, settle 0:37 in, and let’s talk wellness now. And we’re going to take a short pause from our sponsor. I know we’ve got to do 0:44 that, you guys. They’re who keep us on the air. So, I’m going to pause for just a minute and be right back after this 0:50 message from our sponsor. Ladies, it’s time to reignite your vitality. Primal 0:56 Queen supplements are clean, powerful formulas made for women like you who want balance, strength, and energy that 1:03 lasts. Get 25% off at primal queen.com. Serenity Health. That’s primalqueen.com. 1:10 Serenity Health. Because every queen deserves to feel in her prime. All 1:15 right, everybody. We are back. And are you ready? We are talking all things peptide and I am opening the show today 1:23 with sexual wellness. Yes, I’m going there, you guys. I am going there. You 1:29 know, this has really become a big issue for people um of all ages. It’s not just 1:3 4us older people. It’s younger people, too. And there’s a whole variety of reasons why we have sexual dysfunction. 1:42 And when we’re talking about sexual dysfunction, we’re not just talking about it doesn’t work, right? Or I can’t 1:48 reach orgasm. A lot of it is around desire and um the thought of it and 1:54 wanting to connect, wanting to be kinder to one another, wanting to be touching 2:00 one another. A lot of it resolves or revolves around that. And so there are some peptides that can help us and I’m 2:08 really excited to be able to talk about those today. So the first one is called PT-141. 2:14 This targets the brain not the periphery. Right? So for many women I 2:20 will always tell you sex starts between here. It is a brain thing for us. It is 2:26 not necessarily a physical thing. For guys that’s a little different. It’s very physical. For women it’s all in our 2:32 brain. So tip for you men that are listening. You have to prime your woman’s brain first if you want her to 2:38 have sex with you that night. You have to be nice to her. You have to bring her flowers. Do the dishes for her. Do 2:45 something kind. Bring her a cup of coffee or tea or a glass of wine. Take her to dinner. You have to woo her. And 2:51 I don’t care how long you’ve been married. That has to happen. And tip number two, don’t say anything stupid 2:57 that day. I’m just being honest. When you guys say things that make us upset, 3:03 that lingers with us for the rest of the day. And it’s it’s a turnoff for us. And 3:08 for a lot of women, we can’t get past that when it comes time to snuggle at night. And sex doesn’t always have to be 3:14 at night either. So, you can tell I really love talking about this conversation, but we’re going to get into the peptide part of it because this 3:21 is going to help people. So, um, PT-141 is marketed as I’m going to slaughter 3:28 this name, Vali, and it represents a fundamentally different approach to 3:34 sexual dysfunction than the PDE5s inhibitors like Slenden, Viagra, 3:40 Tedataphil, which is Seialis. And while the PDE5 inhibitors work specifically by 3:47 enhancing blood flow to the genital tissues, PT-141 works centrally in the brain by 3:54 modulating neural s neural circuits involved in the sexual desire and 4:00 arousal. Now PT-41 is a cyclic hpatipeptide. It’s seven amino acid 4:07 peptide arranged in a cyclic structure that acts as a melanoortin receptor 4:13 agonist and with particularly the infinity for MC3R and MC4R subtypes. 4:20 It’s actually a metabolite of the melanotan 2, a peptide originally 4:26 developed for tanning that was also found to enhance sexual desire in early 4:31 studies. Now the melanoortin system in the brain is involved in multiple functions including energy homeostasis 4:39 but it also is involved in sexual motivation and arousal behaviors. The FDA approved PT-141 in 2019 specifically 4:48 for the treatment of acquired generalized hypoactive sexual desire 4:54 HSDD in permenopausal women. So for the first time we have a medication that was 5:01 approved by the FDA to use for women for sexual dysfunction. We have had all of 5:07 these seialis tedataphil viagros for men but we had nothing for women. And so 5:12 this is amazing that this is available for women and approved by the FDA. It’s a big deal. This represents the first 5:19 and only FDA approved medication specifically targeting these circuits of sexual desire rather than the peripheral 5:27 arousal mechanisms. And this indication is quite specific, meaning it was developed at some point, not lifelong. 5:35 So I if you’ve had sexual dysfunction your entire life, this medication was 5:40 not approved for you. But if it’s something that you developed over time, like when you went through pmenopause or 5:46 menopause or some women have this experience happen after childirth, that’s what we’re talking about here. 5:53 Now, it’s also not just um supposed to be used if you dislike your partner, 5:59 right? If your relationship is bad and you dislike your partner, this probably isn’t going to fix a ton. It might help 6:05 a little bit, but that’s not what it’s meant for. So, you really have to know what you’re using it for and why. And 6:11 the other thing that I would say is this is something that we don’t go to if your hormones are not balanced properly. You 6:17 have to balance your hormones properly before using something like this because it still may not work. Now, the only 6:24 caveat to that is if you’re a woman that has a risk of breast cancer and can’t use hormones, then that’s a different 6:31 story and we would have that conversation about whether or not this medication would be appropriate for you. Now, the FDA label specifies PTA1 uh 6:39 PT-141 as it not being indicated for HSDD in causes where low sexual desire 6:46 is due to coexisting medical or psychiatric conditions, problems with relationships, like we had talked about, 6:53 side effects to medications or other substance use. This specifically reflects the importance of differential 6:59 diagnosis. Low sexual desire can have many root causes and PT-41 is only 7:05 appropriate when those causes have been ruled out. Now, I have I used PT41 in 7:10 people who have sexual dysfunction issues as a result of using 7:16 anti-depressants. Yes, I have. I’ve used Flynn in that effect as well. And it 7:21 does work sometimes, but it doesn’t work completely. But you need to know that that is not what the approval is for the 7:27 FDA. So that is done in something that we call off label use. So very important 7:33 to know. Now in these clinical trials leading to FDA approval, this was published by Kinsburg and colleagues in 7:40 obstetrics and gyne gynecology in 2019. PT-141 demonstrated statistically 7:46 significant improvements in sexual desire and decreases in distress related 7:51 to low desire compared to placebo. The effects manifest over 45 minutes to 7:56 several hours after the injection and the mechanisms involved modulation of dopamine and melanoorton pathways in the 8:04 hypothalamus and the brain regions that involved sexual motivation. Now cardiovascular effects of PT 141 require 8:12 careful attention. This drug causes transient increases in blood pressure about 3 to four points and transient 8:20 decreases in heart rate. And because of this, it is contraindicated in patients 8:25 with uncontrolled hypertension or known cardiovascular disease. And it has been studied in patients who’ve had recent 8:32 cardiovascular events or sorry hasn’t been studied hasn’t been studied in patients who’ve had recent 8:39 cardiovascular events. So patients need to have their blood pressures checked before starting therapy. Nausea is 8:45 extremely common. It is one of the biggest things I often will tell people to take an anti-nausea medicine if 8:52 they’re going to do this because the last thing you want to do is inject this medication and think it’s going to give 8:57 you this great time with your partner and you’re so nauseated that you can’t even perform, don’t want to kiss, don’t 9:05 want to do anything. It it can be pretty profound for some people. um it does affect about 40% of the patients in 9:12 clinical trials which is why many clinicians require or recommend an 9:17 anti-nausea medication like I had just said other common adverse effects include flushing injection site 9:24 reactions headache in about 13% of the population which I have seen worse if 9:30 people are prone to headaches and the headaches are pretty intense so I will also have them premedicate if they have 9:36 that um sensitivity ity with a Tylenol or Advil, Alie, whatever it is they 9:42 typically use for their headaches to help prevent that from occurring. Now, some patients also experience a 9:50 generalized hyperpigmentation of their skin, particularly in areas with chronic friction, and this may not be reversible 9:57 after discontinuation. So from an integrative perspective, PT-41 10:03 represents one tool in addressing female sexual dysfunction, but it should never be the first or only intervention. And 10:11 low sexual desire in women is complex. Multiffactorial involving hormonal imbalances, low testosterone, estrogen 10:18 deficiency, progesterone imbalances, thyroid dysfunction, adrenal dysfunction, and with elevated or 10:24 disregulated cortisol levels, sleep deprivation, relationship issues, unresolved trauma, including sexual 10:31 trauma, chronic pain, body image concerns, and medication side effects such as SSRIs are notorious for this. So 10:39 a comprehensive hormone panel including total and free testosterones, estradile, 10:45 progesterone, DHEA, thyroid function in cortisol assessment, ideally four-point 10:51 cortisol, salivary should precede any pharmacological intervention. And additionally, addressing the 10:57 psychological component and relationship dimensions through appropriate therapy is necessary. I have a lot of patients 11:03 that say, “This is just too much work for sex. I don’t want the side effects. I don’t want to deal with this.” and that’s totally fine. But for some 11:09 people, their sexual dysfunction is actually causing more problems on their 11:14 relationship and they want to do something to fix that. And just know that if you’re using a peptide like this 11:20 that comes with some of these side effects and you have to premedicate for it, it is not the end of the world. Um, 11:27 but it may be a possibility that you may need that. So, let’s dive into body composition and growth hormone access. 11:34 So Tesmarellin is the only FDA approved GH 11:40 analog. Tesarelin is marketed as Agrifta and Agria SV. It is a synthetic analog 11:48 of human growth hormone releasing hormone. So GH RH human growth hormone 11:53 releasing hormone. These things are such long names it’s confusing and it’s difficult to spit out, right? It 11:59 consists of 44 amino acids. The structure is identical to our own 12:05 body’s growth hormone GHR um with the addition of trans3 hexonol group which 12:14 stabilizes the molecule that extends its half-life compared to the native GHR. 12:19 The mechanism of tesmarellin is elegant in its preservation of physiological 12:24 growth hormone GH secretion patterns and rather than administering an exogenous 12:30 growth hormone directly, tesmarillin binds to the GH receptor in the anterior 12:36 pituitary gland stimulating the indogenous pulsatile release of GH. So 12:42 you know it it’s slower in that stimulation and it pulsates instead of a direct rise and fall. This pusile 12:49 pattern more closely mimics natural GH secretion which occurs in bursts 12:54 primarily during sleep. The GH then stimulates the liver to produce insulin-like growth factor IGF-1 which 13:01 exerts many of the downstream metabolic effects including lipolytic effects on 13:07 the atapost tissue. So fat atapose and how we break that down. The FDA approved 13:13 tesmarellin in 2010 for a very specific narrow indication, the reduction of 13:19 excess abdominal fat in HIV infected patients with lipodistrophe. This 13:25 condition characterized by abnormal fat redistribution with accumulation of visceral body fat and the loss of 13:32 subcutaneous fat in face and limbs developed as a complication of an 13:37 antiviral therapy particularly with older protease inhibitor reg uh 13:42 regimens. The visceral fat accumulation in patients is not just cosmetic. It’s associated with increased cardiovascular 13:49 risk, insulin resistance, and inflammatory markers. The pivotal trial that led to the FDA approval included 13:56 work by Stanley and colleagues published in the annuals of internal medicine in 2014. It demonstrated that tesmarillan 14:03 significantly reduced the visceral atapose measured by CT scan by approximately 15 to 20% which is a 14:10 significant difference to placebo over a short period of time only 26 weeks. Now, 14:16 interestingly, the total body uh weight typically remained stable or even 14:21 increased slightly as the reduction of visceral fat was sometimes offset by increases in lean body mass or 14:28 subcutaneous fat. This highlights an important point. Tesmearellin is not a weight loss drug in its conventional 14:34 sense. Its effects are specifically on body composition and fat redistribution. 14:40 Now the glucose metabolism effects of tesmarellin do require careful monitoring because GH and IGF1 can 14:47 induce insulin resistance. Tesmearellin can increase glucose levels and hemoglobin A1C and in these clinical 14:54 trials glucose tolerance and new onset diabetes occurred in some patients. So 14:59 this creates a therapeutic paradox while res reducing visceral fat we should theoretically improve metabolic health. 15:07 The GH mediated insulin resistance can worsen the glycemic control and patients 15:12 with diabetes require particularly close monitoring. The potential need for adjustment in diabetic medications can 15:19 occur. So I already know what you guys are thinking. Can I use Tesmarellin and 15:24 GLP1 at the same time? And the answer is yes. Especially in those people that we 15:30 know have an insulin resistance already or are prone to that, we can use lowd 15:36 dose micro doing GLP-1 along with tesmarellin to help prevent this from 15:42 occurring um or reduce the risk of it occurring. Now there are some other adverse related problems to growth 15:49 hormone access which include fluid retention which can uh manifest as uh 15:55 ankle swelling, joint pain, muscle pain, paristhesas, carpal tunnel syndrome is 16:01 common to see. Of course you can always see injection site reactions reported about 26 to 30% of the time in the trial 16:08 participants. And this also theoretically has a concern about IGF-1 elevation potentially promoting 16:14 malignancy through long-term data is limited. So we have to be cautious about 16:20 this but it is a growth hormone and anything that is a growth hormone can cause cells to grow and it cannot 16:26 necessarily differentiate between healthy cells and bad cells. So the drug is contraindicated is contraindicated in 16:33 patients with active cancer and in patients with the disruption of the HPA access from conditions like pituitary 16:40 tumors, pituitary surgery, head of radiation um and traumatic brain injury. 16:46 Now off label use of tesmarellin for general anti-aging or body composition 16:51 optimization in non-HIV population, it doesn’t have FDA approval. There is no 16:58 FDA studies. um that promote this, but practitioners do prescribe it for these 17:04 purposes under an experimental and not supported by FDA approved indications. 17:10 And um from an integrative medical standpoint, optimizing natural growth 17:15 hormone secretion through lifestyle interventions, high quality sleep is important. GH primarily is excreted 17:22 during sleep and deep sleep waves. So improving your deep sleep is important. Intermittent fasting can also increase 17:28 growth hormone by five-fold as demonstrated in a Hartman and colleagues uh study from the journal of clinical 17:35 endocrinology and metabolism in 1992. And highintensity interval training, adequate dietary protein, blood sugar 17:42 control, these all can help naturally increase your growth hormone. So, let’s 17:47 dive in now and talk about bone health. peptide hormones um such as oh I’m gonna 17:54 I’m gonna really slaughter this name. Terraparatide is a true bonebuilding 18:01 peptide. It’s marketed as forio. It’s a recumbent form of the first 34 amino 18:08 acids out of 85 of the human parathyroid hormone PTH. It represents a unique 18:13 approach to osteoporosis treatment because it’s one of the few truly anabolic anabolic bone therapies meaning 18:21 it actively binds new bone rather than simply preventing bone loss. The biology 18:26 of parathyroid is fascinating and seemly contraindicated or uh contradictory. 18:32 Continuously sustained elevations of PTH as occurs in hyperarathyroidism 18:37 is catabolic to bone. So people who have hyperarothyroidism typically have significant bone loss 18:44 especially before it’s diagnosed and it causes causes increased bone 18:49 reabsorption loss of bone density increased fracture risk and however 18:55 intermittent exposure to PTH as achieved with once daily uh injections of forio 19:01 has the opposite effect. This intermittent exposure preferentially stimulates osteoblasts bone building 19:08 cells over osteoclasts bone reabsorbing cells and it leads to 19:13 the net bone formation. So terraparatide binds to the PTH receptors on 19:20 osteoblasts and renal tubular cells in bone. It increases the number of 19:25 activity of osteoblasts stimulating the differentiation of osteoblast precursor cells and may 19:32 reduce osteoblast apoptosis basically programmed cell death allowing this bone 19:37 building cell to work longer. The result is increased bone formation, improved bone architecture and tbacular 19:45 connectivity and ultimately increased bone mineral density um particularly in the hip and the spine which is so 19:51 difficult to regain. The FDA approved this medication in 2002 based on pivotal 19:57 studies by Near and colleagues published in the New England Journal of Medicine in 2001 which demonstrated significant 20:05 reductions in vertebral and non-vebral fractures in post-menopausal women with 20:11 osteoporosis. specifically uh reduced new vertebral fractures by 20:17 65% and nonvettebral fragility fractures by 53% 20:23 compared to placebo over a median followup of 21 months. This is really 20:29 incredible because we have not seen this kind of um change uh in other 20:35 medications that we’ve used for osteoporosis. So current FDA approval 20:40 indicates uh this for post-menopausal women with osteoporosis at high risk for 20:46 fracture, men with primary or hypoconatal osteoporosis at high risk for fracture 20:53 and men and women with glucocord cord glucocordide 21:00 induced osteoporosis at high risk for fracture. The high risk qualifier is 21:05 important. uh terrapeptide is reserved for patients with severe osteoporosis, 21:11 multiple fractures, very low low bone density and those who have failed or are 21:16 intolerant of other therapies. The most significant concern for this medication 21:21 is highlighted in a boxed warning with rat toxicology studies where it caused 21:27 osteioaroma which is a bone cancer in a dose dependent and treatment duration dependent manner. The revolence of this 21:34 finding to humans is debated. Rats have fundamentally different bone biology than humans with continuous bone growth 21:41 throughout life and different PTH receptors. Now post marketing 21:46 surveillance in humans hasn’t shown a clear increase in osteocaroma risk but 21:51 theoretically concerns persist and because of this terapeptide is 21:57 contraindicated in patients at risk baseline risk for osteioaroma 22:02 including those with pageantss disease of the bone unexplained elevations of alkaline phosphate prior skeletal 22:10 radiations bone metastases or skeletal malignancies and pediatric patients or young adults 22:16 with open hyes. There’s also a lifetime treatment duration of only 2 years and 22:22 terrapeptide can cause transient hypercalcemia. So an elevated blood calcium and as PTH normally increases 22:31 calcium levels by enhancing bone reabsorption, increasing renal calcium 22:36 reabsorption and promoting activation of vitamin D which increases intestinal calcium absorption. Some patients 22:43 experience orthostatic hypotension within 4 hours of injecting requiring 22:48 caution in at risk populations for blood pressure. Common side effects include 22:53 muscle pain, joint pain, pain in the limbs, nausea, headache, and dizziness. So from an integrative bone health 23:00 perspective, terrapeptides should be part of a comprehensive strategy. Adequate calcium intake, 500 to a,000 23:08 milligrams of calcium a day from food and supplements combined. and vitamin D. 23:13 Getting vitamin D levels of at least 50 to 80 are essential for the drug to work 23:20 optimally. But beyond this, bone health requires vitamin K2, which directs calcium into the bones rather than soft 23:27 tissues, magnesium as a co-actor in bone metabolism, trace minerals like boron, 23:33 copper, silica, and of course, adequate protein intake, which many of us, especially as women, don’t do 0.8 8 to 1 23:42 gram of protein per kilogram of body weight, weightbearing exercise. Of 23:47 course, these all provide mechanical signals that complement the biochemical 23:52 symbol uh signals of terrapeptide. Sequential therapy is also critical. The 23:58 bone mass gains from terraparatide can be lost if patients don’t transition to 24:05 an anti-resorbbitive agent a bisphosphinate after completing this therapy and the anabolic effects to 24:12 build bone but maintaining the new bone requires preventing excess reabsorption. 24:18 So positive things about this but there are definitely some concerns as well. So 24:23 the next one we’re going to talk about is Lu Prolrooide. It is marketed under 24:29 the multiple brand names of Lupron, Depo, Eligard, and it’s a synthetic 24:34 nonapeptide analog of naturally occurring ginonadotropen releasing 24:39 hormone G&R, also called luteinizing hormone releasing hormone, LHR. 24:46 It’s a fascinating example of how manipulating natural hormonal feedback systems can create therapeutic effects. 24:53 So, G&RH is normally secreted in a pulsatile fashion by the hypothalamus 24:59 and travels to the anterior pituitary where it binds to G&R receptors and 25:05 stimulates the release of luteinizing hormone LH and follical stimulating hormone FSH. These ginatotropins signal 25:13 the ovaries or the testes to produce sex hormones, estrogen, progesterone in 25:18 women, testosterone in men. Uh, luoprololi lupron as a GNR agonist 25:26 initially mimics the action of natural G&R causing an acute flare response with 25:33 uh increased LHFSH secretion which temporarily increases sex hormone 25:38 production. However, the continuous administration which is in the depo 25:44 formulations, the GNR receptors in the pituitary become desensitized and 25:50 downregulated. And after about 2 to four weeks of continuous exposure, LH and FSH 25:56 secretion is profoundly suppressed, leading to what’s termed as chemical 26:01 castration. Testosterone levels in men drop to castrated levels less than 50 26:08 and estrogen production is marketkedly suppressed in women. This bifphasic 26:13 response creates both therapeutic applications and management challenges in prostate cancer where tumor growth is 26:20 typically androgen dependent and the ultimate goal is testosterone suppression. However, the initial 26:27 testosterone surge during the flare phase can temporarily worsen symptoms potentially causing increased bone pain, 26:34 urinary obstruction, or even spinal cord compression in patients with metastatic 26:40 disease. This is why uh luoprolide is often started with an anti-ad androgen 26:47 like bicladamide for the first two to four weeks to block the effects of the 26:52 testosterone surge. The FDA has approved lupalide for multiple indications across 26:59 formulations. In oncology, it’s used for palletive treatment of advanced prostate cancers. In gynecology, various 27:06 formulations are approved for endometriosis, for pain management and lesion reduction and for fibroids. 27:13 Typically for pre-operative uh hematological improvement in anemic patients. In pediatrics, it’s used for 27:20 central precocious p puberty basically to halt the premature sexual development of these young people. Now, there are 27:28 adex uh adverse effect profile that reflects profound hormonal suppression. 27:34 In men treated for prostate cancer, hot flashes affect about 59% of the patients. Other common effects include 27:41 general pain, swelling, bone pain. Um long-term use of these medications leads 27:47 to metabolic changes. It increases fat mass. It decreases lean mass. It worsens 27:53 insulin sensitivity, disrupts the cholesterol uh lipid panels, increases 27:59 diabetic risk, has some concerns over cardiovascular disease. And the metaanalysis have shown increased risks 28:06 of heart infarction, myocardial inffection, sudden cardiac death, and stroke in populations receiving 28:13 long-term androgen deprivation therapy. The bone effects are particularly dramatic. Without sex hormones, bone 28:20 density decreases significantly, typically 3 to 4% per year during the 28:26 first two to three years of therapy. And this bone loss may not fully be reversible after the the therapy 28:32 discontinues. The American Society of Clinical Oncology recommends bone density monitoring and consideration of 28:39 bisphosphinates uh in men receiving long-term androgen deprivation. In women treated for 28:46 endometriosis or fibroids, the estrogen suppression creates a hypoestrogenetic state similar 28:54 to menopause. Hot flashes affect 90% of patients with other common effects 29:00 including headaches, emotional irritability, decreased sex drive, vaginal dryness, bone density loss. And 29:08 because of these bone concerns and treatment duration with endometriosis, typically limited to six months, though 29:14 some formulations allow for longer use with adback hormonal therapy to 29:20 partially mitigate these side effects. The mood and cognitive effects can be s 29:25 significant. I’ve seen it over the years. the depression, the memory impairment, difficulty focusing and 29:31 concentrating. It can be very very traumatic and the quality of life that 29:37 happens for these uh women and men can be unbearing for many of them. Um, from 29:44 an integrative perspective, patients receiving this medication need comprehensive support care. Bone health 29:51 interventions using calcium, vitamin D, vitamin K2, weightbearing exercise, 29:58 cardiovascular risk management becomes critical, including blood pressure monitoring, lipid management, diabetes 30:05 screening. For hot flashes management, some patients respond to black coohos, 30:10 sage, or vitamin E. Though evidence is mixed and individual response varies, 30:16 omega-3s may help with the mood and the inflammation, resistance training becomes specifically important to 30:22 preserve lean muscle mass in the face of hormonal suppression. 30:27 Now there’s something called calcetonin salamon which is marketed as miaelin. 30:34 It is a nasal spray. It is now discontinued. And foral is the new 30:39 synthetic polyeptide hormone of 32 amino acids identical to calcetonin of salamon 30:47 origin. It represents an interesting case study in how initial promise gives 30:52 way to safety concerns that regulate a therapy to historical footnote status. 30:58 Calcetonin is naturally occurring hormone in humans. It’s secreted by the paraphalicular sea cells in the thyroid 31:04 gland. Its primary physiological role is to lower blood calcium levels by 31:10 directly inhibiting osteoclast activity, reducing bone reabsorption, increasing 31:16 renal calcium secretion or excretion, and possibly reducing the intestinal 31:21 calcium absorption. So, salamon calcetonin is used therapeutically because it’s more potent and longer 31:27 acting than human calcetonin. The FDA initially approved calceton and salmon 31:34 for several indications post-menopausal osteoporosis in women more than five 31:39 years post-menopausal when alternative treatments are not sustainable. Padet’s 31:44 disease for bone and hypercalcemium as emergency treatments. The nasal spray formulation is particularly popular for 31:53 osteoporosis because it offered a non-injectable alternative to bisphosphinates. 31:58 However, in 2012, the European Medicine’s Agency, EMA, conducted a 32:05 comprehensive safety safety review after a poolled analysis of 21 clinical trials 32:10 involving over 10,000 patients showed a statistically significant increase in 32:15 malignancy risk in patients treated with calceton salamon compared to compared to 32:21 placebo. The overall malignancy rate was 4.1% in calcetonin treated patients 32:28 versus 2.9% in placebo patients. The types of cancer 32:34 varied with no single cancer type predominating, making it difficult to establish a clear mechanistic link. 32:41 However, the signal was concerning enough that the EMA restricted the use of calcetonin containing medicines. In 32:48 the United States, the FDA issued communications about malignancy signal and conducted its own review. While they 32:56 didn’t fully withdraw the drug, the cons consensus shifted dramatically. The nasal spray formulations miaelson was 33:03 voluntarily discontinued by the manufacturer and current clinical practice guidelines now consider 33:10 calcetonin salamon as a second line or lower option for osteoporosis. While 33:15 behind bisphosphinates, dennism mob, uh, terrapeptide, the analesic effect of 33:21 calcetonin in bone pain, particularly in acute vitibbral, uh, compression 33:26 fractions from osteoporosis or pageantss disease may still provide a role for short-term use in these selected 33:32 patients. The mechanism of this pain relief is unclear, but may involve 33:38 effects of endorphin systems and/or direct actions on pathways. The history serves as an important reminder in 33:45 peptide medicine. Initial approval and early clinical use does not guarantee 33:50 long-term safety effects. Post marketing surveillance and poolled analysis of the clinical trial data can reveal adverse 33:58 effects that weren’t apparent in initial studies. It also underscores why newer 34:04 agents with better safety profiles um have largely replaced calcetonin in 34:10 clinical practice. So this is really an important thing. Not one thing stays the same forever. We have to change as we 34:18 identify new and better products as we identify problems and concerns. I will 34:24 always tell my patients if you are uncertain of taking a new drug which we 34:30 all should be wait five years. Within five years we are going to find the 34:36 problems that they didn’t find in the clinical studies. Remember, a lot of these clinical studies are small, small 34:43 groups, short periods of time. It’s expensive to do these trials. So, if you 34:49 wait for five years, in the first two to three years, you will see the problem start to emerge. And what are you going 34:55 to look for? You’re going to look for the the news um commercials from lawyers 35:02 suing a drug. And they will tell you what the problem is. and then you can decide, is this something that I want to 35:09 use or not. Don’t jump on bandwagon and be the first one to do this, especially 35:14 if you’re sensitive. You know, give it time so you can see exactly what’s going on. So, I’m going to end our show on 35:22 this and we are going to pick up on part three of peptide therapy in our next 35:28 segment where we’re going to talk about the investigational peptides and some 35:34 exciting things that are happening with that. So, I want to thank you for joining me today on Let’s Talk Wellness 35:39 Now. It’s always a pleasure having a conversation with you guys and I hope this brings value to you with what we’re 35:45 talking about. If you have ideas for topics that you want me to discuss, 35:51 please message us, you can share your comments on Facebook, you can email us, 35:58 um you can get a hold of us however you would like to share that. I do look at the comments below in the episodes as 36:04 well. So you can place your comments there. And once again, one of the best things you can do for me is like, 36:11 subscribe, and share so that we can spread the messages of what we’re doing. 36:16 I do this at no cost. I don’t make any money out of this. I do this as an 36:21 educational purpose for everybody else. I love doing it, but it really helps us 36:28 on the algorithms if you would be just willing to like, subscribe, and share. 36:33 So, thank you for spending your time with me. I know time is important.The post Episode 257 – Peptides for Sexual Wellness & Hormonal Health: PT-141, Growth Hormones, Bone Health & More! first appeared on Let's Talk Wellness Now.

Limitations of Conventional Parkinson's Treatment; Dietary Neurotoxins and Dopamine Cell Damage; Protein Excess and Dopamine Interference; Dopamine Pathways and Cell Protection; Medication Masks Symptoms but Doesn't Slow Disease; Early Cell Loss in Parkinson's and Prevention; Animal Fat Increases Parkinson's Risk; Organochlorine Pesticides and Brain Cell Death; Dairy Products Contain Neurotoxic Residues; Dairy and Parkinson's: Dose-Response Risk; Dairy Reduces Protective Uric Acid and Adds Toxins; Cheese and Pizza Amplify Disease Risk; Scientific Consensus Against Dairy in Parkinson's; Common Dairy Toxins Trigger Brain Inflammation #Parkinsons #BrainHealth #NeuroNutrition #HealthTalks

Please share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.comThe Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder: [ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]http://www.transcendcompany.com/nylenaygaRP Hypertrophy Training App: rpstrength.com/nyle00:00:00 - Intro00:02:40 - Podcast Start00:03:00 - Turkey Hair Transplant00:04:50 - Quitting Finasteride00:09:18 - Skull Needles & Anesthesia00:11:46 - Piercings Gone Wrong00:14:26 - Nipple Piercings00:17:15 - Meeting Melissa00:21:00 - 12 Weeks Out?00:24:11 - 90s Hardcore vs. Science00:32:10 - Digestion First00:37:00 - Off-Season Insulin Strategy00:40:48 - Gaining 15lbs in 3 Weeks00:42:37 - No More Chicken00:46:12 - Eating Raw Testicles00:49:04 - Fruit & Digestion00:50:48 - High Volume Training00:56:23 - How My Calves Died01:02:00 - Best Body Part01:05:49 - Vacuum & Gut Control01:08:00 - Career PED Dosages01:13:00 - GH & Insulin Timing01:16:48 - Insulin & Digestion01:19:00 - Current Cycle (300 Test)01:20:56 - Feeling Small (Deflated)01:24:46 - The IVF Journey01:27:10 - Gender Selection Laws01:28:22 - Daily Micro-Injections01:29:58 - The PMMA Scandal01:33:07 - No AIs Needed01:35:18 - Deca vs. Masteron01:37:05 - Why Masteron Now?01:38:52 - Aromatization Genetics01:41:47 - Future Cycle Plans01:47:55 - The 99ng/dL Crash01:53:23 - Peptides for Repair01:55:35 - Retatrutide for Bulking?02:01:11 - GHK-Cu for Skin02:02:40 - The White Fish Diet02:07:54 - Hybrid Training is a Trap02:09:30 - The Mindset of Peeled02:14:00 - Finding Your Volume Limit02:18:20 - The McDonald's Rebound02:22:11 - Marriage & Prep02:27:13 - The Greg Doucette Beef02:29:11 - Fertility on Gear02:32:30 - Patrick Tuor Era02:37:34 - Coaching CBum02:41:28 - 2024 Olympia Placings02:42:16 - The Smoking Video02:44:20 - Advice for Young Blasters02:46:06 - The "Trauma Pro"02:48:44 - Final Message

Please share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.comThe Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder: [ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]http://www.transcendcompany.com/nylenaygaRP Hypertrophy Training App: rpstrength.com/nyleTimestamps:00:00:00 - Intro00:03:19 Father Steve00:05:28 Banned on Social Media00:07:45 Raving00:12:06 Harm Reduction for Partying00:13:36 Alcohol Toxicity & "Cocaethylene"00:15:25 The Ultimate Hangover Stack00:18:54 Injectable Glutathione & NAC00:23:00 Rave Fashion: Cyclops Shades00:24:34 The Lifestyle Cutting Stack (TRT + GLP-1)00:26:58 The Crackdown on Peptides00:27:53 Cagrilintide Nightmares00:29:29 Orlistat & "Oily" Disasters00:31:36 Peptides for Naturals?00:33:57 The Sting of GHK-Cu00:35:23 Injectable Winstrol00:36:16 YK-11 vs. Superdrol00:39:21 Follistatin: Hype or Real?00:43:04 Mitochondrial Health Stack00:46:24 When to Start TRT?00:47:30 Adding Primo or Masteron00:50:36 My Tequila Mistake00:51:14 My Full Health Protocol00:53:11 What NOT to Take at Parties00:59:11 GHB vs. Alcohol01:00:00 High-Dose Melatonin01:02:17 Competitive Prep Stacks01:06:21 Nyle's Contest Cycle Revealed01:07:24 The "Pharmacy" Load01:13:38 Protecting the Brain (Neuroprotection)01:16:54 Epitalon & Longevity01:20:12 SGLT2 Inhibitors ("Biker Flows")01:21:15 Methylene Blue & Serotonin Syndrome01:24:42 Nootropics: Alpha GPC & Choline01:27:00 Noopept & Bromantane01:30:03 Tanner's Aston Martin01:34:55 Chinese Generics & Heavy Metals01:38:14 1000ng/dL Naturally?01:44:06 Underrated Meds (Telmisartan)01:46:24 Managing Cholesterol01:50:41 Equipoise Anxiety & Kidneys01:56:53 Hair Loss Prevention02:04:33 The "Femboy" Aesthetic Trend02:07:33 Future Drugs (Retatrutide)02:20:58 GLP-1s Saving Marriages02:23:18 Training Volume in Prep02:24:53 Low Iron in Bodybuilders02:27:12 Top 3 Steroids Ranked02:28:55 Substitutes for Primo/Mast02:30:52 Best Beginner Cycle02:34:44 Conceiving on Cycle02:38:16 Post-Cycle Muscle Retention02:41:40 Steve's Ladyboy Story02:50:49 NPP & Neurotoxicity02:52:10 Closing Wisdom

Renaissance Periodization: Training on gear vs. natty, how training styles affect the look of one's physique, slow vs fast twitch training, intensifiers & myoreps, peptides, the future of PED's, & myostatin inhibitors. The Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder: [ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]http://www.transcendcompany.com/nylenaygaRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.com00:00:00 The Red Skin Phenotype00:01:25 Trensparent Origins00:03:23 Visual Diagnostics00:07:23 The Roundness Myth00:10:47 Vibes vs. Physiology00:15:46 The Failure Paradox00:18:15 Volume Kings00:22:23 The Thailand Spirit00:25:16 Genetic Determinism00:30:30 The Volume Response00:36:03 The DUP Protocol00:38:44 Glass Cannons00:43:42 The Recovery Trap00:51:37 Tech-Enhanced Gains00:54:00 Intensifier Logic01:04:02 Weed & Gains01:09:00 The Booty Clap Test01:10:12 The God Stack01:16:18 Exercise Mimetics01:18:04 The Post-Steroid Era01:24:12 The Final Message

The Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder: [ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]http://www.transcendcompany.com/nylenaygaRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.comTimestamps:00:00 Intro05:00 The Patrick Tuor Strategy06:36 The 10-Gram Cycle Myth10:42 Winning a Pro Card on Orals13:53 Engineering Degrees & Bodybuilding21:05 The Best Version of Justin (2016)26:23 Emergency Room Horror Stories28:19 Olympia Afterparties Exposed33:58 Samson Dauda & Travel Meals37:26 Genetics: Muscle Bellies & Skin Thickness38:53 The Pop-Tart Peak Week Disaster45:07 Dangers of Cookie Cutter Cycles47:25 The 1000mg Testosterone Standard50:21 Hyper-Responders vs. Hard Gainers55:40 The 20lb Rebound Phase59:34 Building a Freak Natural Base01:02:13 Failing Classes for Prep01:08:24 Bodybuilders in Bar Fights01:14:30 Old School "Factory" Protocols01:28:22 Insomnia & Dementia Risks01:32:19 Generic vs. Pharma GH01:36:47 18IU Insulin Pre-Workout01:41:56 IGF-1 for Massive Legs01:45:32 The Infection That Ruined Prep (C. Diff)01:51:34 Increlex: The Nuclear Option01:56:40 Underground vs. Pharmacy Gear Strength01:59:25 Halotestin Rage & High Blood Pressure02:07:53 Hair Loss: Thyroid vs. Gear02:14:21 Eating Bear Meat in Alaska02:20:35 The 3 Heart Tests You Need02:32:37 Peaking for the Texas Pro02:40:12 Q&A: High Dose Winstrol Loading?02:49:15 Training 30 Weeks With No Rest02:51:54 Perfect Insulin Timing02:55:37 Fixing the IFBB Pro League03:06:20 Conclusion & Life Advice

The Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder: [ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]http://www.transcendcompany.com/nylenaygaRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.comTimestamps:00:00:00 Intro00:01:26 Holidays & Work00:02:14 Vegas vs. California: The "Realness" Factor00:03:00 The Secret to 23-Inch Arms00:04:57 Genetics: Korean Calves & Ethnic Muscle Insertions00:06:30 The New Generation of Bodybuilders00:08:27 The Boston Lloyd Controversy: Truth vs. Harm00:13:11 Debunking the "10 Grams of Gear" Myth00:14:53 Natural Bodybuilding & Social Media Expectations00:16:47 The Limitless Mindset00:18:52 Evan's Origin Story: From Obese to Anorexic00:20:39 The "Perma-Cut" Trap: Fear of Eating00:22:46 Drugs Are Tools, Not the Foundation00:25:42 Losing Gains to Stay Lean (The Teenage Mistake)00:28:03 Winning the First Show & Turning Pro00:28:27 Starting PEDs at Age 19 (500mg Test)00:30:51 First Cycle Results & The "Cold Turkey" PCT00:32:45 Coming Off Gear: Bloodwork Reality Check00:34:28 Rebound Strategies: Staying On vs. PCT00:36:58 Testing TRT Levels & Fertility00:39:53 Host Message: Subscribe & Sponsors00:41:03 First Growth Hormone Experience (Serostim)00:41:50 The Holy Trinity: Test, Tren, & Winstrol00:44:12 Injectable Winstrol: Alpha Pharma Rexogin00:46:26 Oral Winstrol Side Effects: Gut Health & Acne00:49:02 Quitting Orals (Reflux Issues)00:51:55 Modern Coaching Lunacy: High Dose Orals00:53:26 Acute Toxicity: Why Injectables are Safer00:58:09 Finding "Real" Injectable Winstrol 101:00:55 GH Strategies: Prep vs. Off-Season01:02:13 Insulin Without GH? The Joe Palacios Anomaly01:03:11 Is Growth Hormone Overrated?01:04:26 Cycling GH: 2 Days On, 1 Day Off01:05:21 The Ronnie Coleman Standard01:06:09 The GH15 Era & Internet Rumors01:09:42 The "One Bottle of Sustanon" Pre-Stage Protocol01:13:28 GH Frequency Debate01:16:19 What Pros Actually Take: The 4-6 IU Reality01:19:02 Steroids in Japan01:20:41 Earning the Pro Card01:21:10 2009 NY Pro Win & The Oscar Ardon Era01:23:58 Passion vs. Career: The Bodybuilder's Dilemma01:28:44 Evan's Heaviest Cycle: 1,500mg Test & Suspension01:30:55 The Cytadren (Aminoglutethimide) Nightmare 201:32:43 Diuretics & Dangerous Prep Protocols01:34:26 Insulin Frequency & Diabetes Risk01:37:53 Dangerous Modern Coaching: 100mg Orals Daily01:40:15 Longevity & The "One Vice" Rule01:43:45 Essentiale Forte: The Ultimate Liver Supplement 301:45:33 Host Message: Transcend HRT01:46:20 Training Philosophy: Oscar Ardon's "Mental Torture" 401:50:38 Science-Based Op

Placing 2nd at Texas Pro. Real talk the whole time, everything you'd want to know, from the deep sht to how they blew up and the juicy deets in between. Honored to know these bros. The Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder: [ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]http://www.transcendcompany.com/nylenaygaRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.com00:00:00Intro 00:02:21The Post-Show Dopamine Crash vs. Prep "Grumpiness"00:02:42Relationship Survival Guide: "The Pre-Emptive Apology"00:04:31Reading Cortisol: Why "Low" Can Be Worse Than "High"00:05:12Adrenal Burnout Protocol: "Baby Sessions" & No Cardio00:06:52Elliot's Pro Debut: Navigating the "Growing Pains"00:07:29The "Food Noise" Reality: When One Donut Turns into Four00:08:03Retatrutide ("Retta"): The 2mg Protocol for Appetite Control00:09:19Flashback: The Misery of the 1100-Calorie Natty Prep00:12:14The Cult Following of the Unranked Podcast00:14:41The Origin Story of the "Unranked" Name00:16:19The Great Debate: Health Phase vs. Aggressive Rebound00:18:43The Burnout Checklist: When to Abort the Rebound00:20:10Metabolic Adaptation: When the Body Stops Responding00:23:29Methylation Hacks: Methyl Folate & The MTHFR Mutation00:25:31The "Mic Check" Comedy Segment00:28:05Andrew's Origin: The Magazine Era (1996)00:33:58Kyle's Origin: The Mentorship Era (2014)00:37:54Joining the "Dark Side" at Age 10? (Andrew's Story)00:39:57Andrew's First Cycle: The "Tren & D-Bol" Kitchen Sink00:42:00Kyle's First Cycle: Pro-Hormones & Peer Pressure00:43:19The "Mad Scientist": Snorting Andro at Age 1400:45:10The Golden Rule: Wait Until 25 (Or 30)00:47:09The "Natty Ceiling": Switching to the Dark Side (Chris's Story)00:49:58The Halo-Only Nightmare: A Lesson in Hormonal Crashing00:56:27Financial Advice for Young Pros: Freeze Your Sperm01:03:16Training Mistakes: The "Two-a-Day" Trap01:06:57The Meadows Hack: Binge Until You're Sick01:10:54The "Dreamer Bulk" Mistake: Fat Doesn't Turn to Muscle01:13:00The Secret to Rebounding: Stay "Hungry" & Insulin Sensitive01:21:38Executing the Health Phase: Diet & Training Adjustments01:26:47The "Zero Carb" Depletion Experiment (Martin's Protocol)01:35:19Peak Week Orals: Managing Winstrol & Digestion Issues01:40:52The "Detox Week" Protocol: No Training, Med Diet01:44:11Setting the Cap: Max Weight Gain Post-Show (10-15%)01:49:49The "Soft Landing": Using Primo/Proviron to Bridge01:51:25The "No-Go" List: DNP & Dangerous Diuretics01:

Placing 2nd at Texas Pro. Real talk the whole time, everything you'd want to know, from the deep sht to how they blew up and the juicy deets in between. Honored to know these bros. The Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder: [ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]http://www.transcendcompany.com/nylenaygaRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.com00:00:00Intro00:03:43First Cycle Experience00:06:1290s Mentality vs. Modern Science00:08:00Mental Side Effects & Anxiety00:09:22"Death Face" at the 9-to-500:15:51Fat Kid to Anorexia: The Origin Story00:23:51The 80lb Binge Eating Rebound00:26:34Losing Dad & Finding Purpose00:34:52The Reality of Being 300lbs00:40:17Blood Work & Kidney Health00:45:22Coming Off vs. Cruising00:58:198,000 Calories & The McDonald's Diet01:08:49Growth Hormone & Insulin Protocols01:13:01Injection Sites: The "Ass Fat" Method01:15:51Sleep Apnea & The Death Rattle01:21:15The Secret to Transformation01:36:02The Disney World Scooter Incident01:37:49Gaining 50lbs in One Cycle01:45:07Dosage Evolution (Year 1 to Pro)01:51:23Crying While Force Feeding01:58:17Current Cycle Reveal02:09:26Training: Volume vs. Intensity02:15:20The "Death Cocktail" Prep Cycle02:23:12Essential Health Supplements02:45:07Final Message to the World

The Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder: [ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]http://www.transcendcompany.com/nylenaygaRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.comTimestamps:00:00:00 – Intro00:02:28 – Remote vs. In-Person Peaking00:03:50 – Data Driven Coaching00:06:13 – First Cycle Philosophy00:09:31 – Post-Show Buffer Protocol00:11:02 – The Estrogen Myth00:14:14 – The Calcium Score Imperative00:15:59 – The Vitamin D3 Danger00:17:49 – Death by Potassium00:20:23 – Halo vs. Superdrol00:27:37 – Thyroid Tapering00:30:59 – Western Medicine vs. Bodybuilding00:33:16 – The Rebound Phase00:37:42 – Female Androgen Health Effects00:44:31 – Metformin vs. Berberine00:48:18 – Myostatin & The Future of PEDs00:52:23 – Training is what matters most00:58:00 – Fixing Back Training01:05:26 – From Dietitian to Super Coach01:14:32 – Insulin Sensitivity & Gut Health01:23:03 – Peak Week Glucose & GI Health Management01:31:01 – The Dyazide Strategy01:41:02 – The GLP-1 Trap01:54:31 – Classic Physique Weight Cuts01:56:14 – Stanimal Case Study02:09:48 – Insulin & HGH Synergy02:15:42 – Why Modern Bodybuilding is Soft02:21:35 – Designing the Offseason Cycle02:37:05 – Waist Control Secrets02:40:33 – Nick Walker & Coaching02:43:27 – Female PED Safety02:52:36 – Fertility & Sperm Banking02:55:40 – The Final Message

How he improved drastically from his last year with Jansen - Did he deserve to beat Urs?  ⁨@Quintbeastwood⁩  YoungLA BLACK FRIDAY SALE: https://www.youngla.com/discount/nyleCode ‘NYLE' for 30% off to support the podcastThe Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder: [ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]http://www.transcendcompany.com/nylenaygaRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.comTimestamps:00:00:00 – Intro00:08:41 – Why This Was His Best & Most Consistent Season Ever00:14:05 – How Much Easier This Prep Was vs. Matt Years00:19:40 – The New York Pro That Broke Him00:26:47 – Off-Season Weight, Calories & Smarter Approaches00:36:55 – Peak Week Breakdown: Depletion + Carb Loads00:44:00 – Glutamine Mega-Dosing & Gut Health for Peak Week00:47:21 – Germany Show Was His Favorite Trip Ever00:49:34 – What Quinton Packs for Overseas Shows00:55:26 – Running Almost No Orals vs. Winstrol Experiment01:00:17 – Managing a Tiny Waist on Stage01:04:34 – Water Manipulation Mistakes & Lessons01:10:09 – Why Self-Coaching Gave Him His Best Season Ever01:13:50 – Salt, Spillover & Why Judges Prefer Fuller Looks01:19:00 – The Look Judges Want From Quinton01:23:17 – When You Can't See Yourself Objectively01:25:17 – Judges Reward Muscle Pressure Over Shape01:34:19 – Staying Smiling & Confident on Stage01:46:31 – Bodybuilding Pulled Him Through Ruts01:53:06 – PPL vs. Bro Split Thoughts01:56:56 – New Health Phase: Cardio & Controlled Food02:01:23 – Balancing Opinions With Self-Analysis02:04:26 – Prioritize Training Above All02:09:10 – Peptide Recovery: MOTS-C & BPC-15702:20:15 - Leg Cramps02:29:44 – Brittany Brought Life Balance02:32:32 – Say “F*** It” & Take Risks02:33:41 – Kidney Health on Point02:35:55 – Message to the World: More in Common02:38:48 – Closing Thanks & Giant Potential

Dr. Dean St. Mart returns.YoungLA BLACK FRIDAY SALE: https://www.youngla.com/discount/nyleCode ‘NYLE' for 30% off to support the podcastThe Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder: [ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]http://www.transcendcompany.com/nylenaygaRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.com00:00:00 Intro00:06:11 NHS Hospital Nightmare & Surgery Delays00:17:45 Enhancement Perspective – Shoes, Tech & Humanity00:22:32 Fast vs Slow Metabolizers Explained00:30:19 Best Injection Sites: Glutes vs Delts00:38:01 10 Grams of Test 00:45:00 Posing Injuries & Calf Cramp Story00:55:19 Dean's Full 2024 Contest Prep Cycle01:05:31 Reps in Reserve Revolution – Growing With Less Drugs01:21:03 Low-Dose Stack – Slow & Steady Wins01:32:45 Stomach Acid & Bile: First Line of Defense01:42:09 Androgenic Overload – Hair Loss & Acne Signals01:52:51 Modern Abuse: 3–4g Doses Without Results02:06:26 Why Coming Off Gear Can Boost Gains02:15:14 GH Dosing Deep Dive02:24:41 SubQ vs IM GH Absorption Debate02:32:49 Systemic vs Local Effects (GH & IGF-1)02:39:11 Protecting Your Future Health02:40:12 Podcast Wrap & Goodbye

4th at Olympia 2025, 5th at Olympia 2025, & Prague Pro ChampThe Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder: [ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]http://www.transcendcompany.com/nylenaygaRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.comTimestamps:00:00:00 Intro00:10:13 Sleep Stack: Melatonin, GABA, L-Theanine00:16:34 Pittsburgh Pro Miss & Mental Reset00:20:36 Olympia Flatness vs. Prague Peak00:25:12 Prague Peak Recipe Perfection00:31:10 Olympia Migraine Backstage00:35:23 Earlier Hammer Drop (6 Weeks Out)00:40:20 Strict Salt/Water Tracking (10g/5L)00:44:49 Pulling Test Early in Open vs. Classic00:53:18 Yo-Yo Feeding Strategy01:00:36 TB-500 & BPC-157 for Injuries01:04:47 Winstrol Sides & Inflammation01:10:16 Blue Collar to Pharmacy Journey01:18:23 Beating 5 Mr. Olympia Champs01:24:49 Data-Driven Confidence01:34:29 Anti-Shrink Secrets01:36:48 Slow Gains, Max Detail01:44:41 Videographer Coop Magic01:47:18 Cream of Rice Hack01:51:17 Water Retention Balance01:55:24 Fat-Holding Edge02:01:03 Lean Protein Choices02:03:21 Muscle Fatigue Battles02:08:00 X-Frame Strategy02:11:14 Dehydration Balance02:12:47 Parabolan PED Vibes02:15:21 Bloodwork Monitoring02:20:03 Insulin Off-Season Use02:23:01 Insulin & Cardio Effects02:27:00 Insulin & Blood Pressure02:30:00 Insulin & Test Levels02:33:30 Glutamine GI Benefits02:36:45 Tips for Sport Success02:40:56 Grateful for Bodybuilding02:44:33 Journey Support Thanks

Olympia 2025 for 212 bodybuilding shocked people. John Jewett took over Shaun's prep for Olympia and brought an unexpected package vs. Keone Pearson.The Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder: [ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]http://www.transcendcompany.com/nylenaygaRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.comTimestamps:00:00 – Intro02:31 - Catching up08:44 – Why Competing Overseas Is a Nightmare12:36 – Judge Feedback: Fuller + Chest/Quads20:51 – Shaun Clarida's Best Olympia Peak Ever24:00 – Rebounding After 2024 Olympia30:33 – Peak Week Strategy: Simple Always Wins32:27 – Managing Backstage Chaos at Olympia36:20 – Zero Diuretics for Shaun Clarida41:15 – Peaking Pro Tip: Start Simple44:41 – Data Logging = Perfect Peaks45:30 – Shaun's 182lb Magic Window48:53 – Fake GH? What Happens When It's Pulled50:01 – Clen Mistakes & Monster Carb Loads56:00 – Simple Peaks Beat Complicated Protocols58:30 – Martin Fitzwater's MONSTER Fill-Out01:00:47 – Sodium Strategy: 3–5g Daily01:06:57 – Backstage Snacks: Glucose vs Fructose01:12:10 – The 3-Exercise Pump Routine01:18:33 – Winstrol Experiment: Fuller but Softer01:25:28 – If You Could Only Run One Steroid…01:26:51 – SuperDrol: Bull Mode01:32:23 – Shaun's Training: Less Volume, More Gains01:38:40 – Fasted vs Fed Cardio01:43:04 – Steady-State Wins for Conditioning01:50:42 – Cutting the GI Protocol Down01:58:22 – Retatrutide Update & Lipid Focus02:00:14 – Masteron Muscle Myth Busted02:04:16 – Biggest Regret: Should've Hired a Coach02:06:09 – Pro Life: Keep Showing Up02:16:24 – Final Message

2025 Olympia, Family, PED's, & From The Start Til NowThe Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder: [ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]http://www.transcendcompany.com/nylenaygaRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.com00:00 – Intro00:01:42 – Marriage & Relationship Challenges During Prep00:04:27 – Filipino Inspiration & Bodybuilding Legacy00:07:15 – Coaching Joven to the Olympia00:11:09 – Rebuilding After the 2018 Crash00:14:25 – Top 10 Validation & Shutting Down Haters00:16:56 – Stoik Gym: Local Grind to Global Expansion00:21:18 – 18-Hour Prep Days: Building the Blueprint00:25:24 – Fatherhood Struggles During Prep00:31:25 – PED Awareness & Brain Chemistry00:35:07 – Downfall Lessons & Accountability00:43:18 – OCD Since Age 6: Pain to Empathy00:48:59 – Career Rollercoaster & Public Perception00:56:09 – Stoik Vision: Pros Building Pros00:59:46 – Attitude Kills Deals: Losing Everything01:03:18 – The Total Package: Physique + Communication01:06:41 – Backstage Battles & God's Plan01:12:54 – TRT, Peptides & Health Optimization01:17:02 – Proud Dad Shift: Value Beyond Stage01:26:45 – Recovery Mindset: Faith & Muscle Memory01:31:15 – Diet Is King: 5–6 Meals Over Gear01:35:57 – Final Message: Treat People Right, Kill Loneliness

Olympian & 3x Classic Pro ChampThe Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder: [ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]http://www.transcendcompany.com/nylenaygaRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.comTimestamps:0:00 - Intro01:26 - Starting Chat and Merch Talk10:35 - Early Training & First Competition20:32 - Post-Show Binge & Taco Bell Story27:07 - Dessert Obsession & Mukbang Talks33:17 - Low Libido in Prep & Recent Wins36:12 - Dealing with Losses & Growth Mindset40:24 - Embracing Suffering & Process48:23 - Lessons from Last Season & Positivity54:17 - Pressure, Stability & Financial Struggles56:01 - Vegas Trip & First Flights1:03:07 - Travel Strategies & Pro Lifestyle1:12:18 - Hardships, Inspiration & Adversity1:16:12 - Competing Against Daniel & Stage Reality1:18:59 - Tanning & Glaze Lessons1:25:16 - Backstage Anxiety & Timing Errors1:31:08 - Pump Timing & Anxiety in Prep1:46:55 - Classic Division Surprise & Point System1:52:54 - Passion for Competing & Vegas Vibes01:55:07 - Post-Show Health & Growth Strategy2:02:09 - Progress Pics & Cycle Breakdown2:07:20 - Low Dose Philosophy & Longevity2:10:28 - Lab Work & Supplement Insights2:31:09 - Posing Flow State & Stage Confidence2:34:52 - Prep Reduces Anxiety & Staying Ready02:39:38 - Gut Health & Peak Week Tactics2:44:31 - Back Weakness & Training Fixes2:48:15 - Olympia Predictions & Expo Stage Chat3:00:39 - Final Show Reflections & Lessons3:03:29 - Olympia Hype & Vegas Linkup Plans03:04:26 - Control What Matters & Gratitude3:05:24 - Clothing Deals & Meeting Appreciation3:06:29 - Transparency & Meaningful Impact3:07:09 - Vegas, Brownies & Farewell

Olympian in 212 and now Classic.  @thedurrah  The Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder: [ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]http://www.transcendcompany.com/nylenaygaRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.comTimestamps:00:00 - Intro03:19 - Carb Up & Diuretics08:45 - Lineup Drama & Feedback15:19 - Full vs Dry Debate20:58 - Bloodwork Wins & Health Markers25:43 - Water Retention & Dosing40:32 - Schedule Stress & Experience Edge50:06 - 212 vs Classic Prep57:48 - Surgery Loss to Suicide Shift01:03:48 - Quick Q&A & Peak Strategies01:06:26 - Future Moves & Olympia Cycle01:11:39 - Rebound Tips & Self-Coaching01:13:37 - Fatherhood Paradox & Olympia Path1:17:46 - Peace Out

Evidence-Based Olympian IFBB Coach of pros like Jordan Hutchinson & Host of IFBB AMAThe Bodybuilding-friendly HRT Clinic - Get professional medical guidance on peptides AND optimizing your health as a man or bodybuilder: [ Pharma Test, IGF1, Tesamorelin, Glutathione, BPC, Semaglutide, Var troche, etc]http://www.transcendcompany.com/nylenaygaRP Hypertrophy Training App: rpstrength.com/nylePlease share this episode if you liked it. To support the podcast, the best cost-free way is to subscribe and please rate the podcast 5* wherever you find your podcasts. Thanks for watching.To be part of any Q&A, follow trensparentpodcast or nylenayga on instagram and watch for Q&A prompts on the story  https://www.instagram.com/trensparentpodcast/Huge Supplements (Protein, Pre, Defend Cycle Support, Utilize GDA, Vital, Astragalus, Citrus Bergamot): https://www.hugesupplements.com/discount/NYLESupport code 'NYLE' 10% off - proceeds go towards upgrading content productionYoungLA Clothes: https://www.youngla.com/discount/nyleCode ‘NYLE' to support the podcastLet's chat about the Podcast:Instagram: https://www.instagram.com/trensparentpodcast/TikTok: https://www.tiktok.com/@transparentpodcastPersonalized Bodybuilding Program:  https://www.nylenaygafitness.com00:00 - Intro00:04:00 - Value of Transparency & Gear Evolution00:09:24 - Genetics and Drug Strategies00:14:10 - Post-Surgery Growth & Gear Myths00:19:30 - Smart Training & Rebound Management00:26:50 - TRT, Recovery & Tissue Retention00:32:40 - Parasympathetic Recovery & Sleep Struggles00:37:20 - Individualized Training & Overtraining Risks00:43:50 - Smart vs Hard Training Myths00:48:24 - Chest & Leg Training Insights00:52:30 - Jordan's Olympia Prep & Peaking Strategy01:00:00 - Stress-Free Prep & Weight Management01:05:15 - Sleep Hacks & HRT Checkups01:09:04 - James' Prep & Fullness vs Condition01:15:20 - Fruit, Food & Force-Feeding Myths01:22:00 - Gear Balance & Client Collaboration01:26:20 - Retatrutide & New Drug Cautions01:29:29 - Fat Loss Stories & Microdosing01:33:15 - Prep Catastrophes & Client Communication01:38:08 - Offseason & Reverse Diet Strategies01:51:28 - Post-Show & GH Timing Tips02:01:10 - Sugar Timing & Glycemic Control02:06:54 - Stage Experiences & Confidence02:12:11 - Carb Cycling02:24:41 - How Chris Started with James 02:34:10 - Chest Support Pads Restricting Stretch02:38:46 - Final Question