Podcasts about RH

Rodgers & Hammerstein ushered in a new style with Oklahoma! in 1943, and soon, the old styles died away, putting up various degrees of resistance as they did so. Irving Berlin and Cole Porter both adopted a more R&H approach with their late 40s musicals, but it wasn't only existing masters who were influenced by the new approach. 1950 brought Guys & Dolls to Broadway, with Frank Loesser making his debut as a Broadway composer. Is it the best musical comedy ever written? It certainly belongs in the conversation, as we discuss in our episode on "Fugue for Tinhorns." All clips are from a 1951's cast recording of Guys & Dolls: A Musical Fable of Broadway and are protected by the Fair Use guidelines of Section 107 of the Copyright Act for criticism and commentary. All rights reserved to the copyright owners. Listen to the SMSTS playlist on Spotify! Follow SMSTS on Instagram: @somuchstufftosing Email the show: somuchstufftosing@gmail.com Recommended Reading/Viewing: Ethan Mordden, Anything Goes: A History of American Musical Theater (Mordden's other volumes are also excellent resources for more in-depth discussion)Broadway: The American Musical

Nach dem Schwimmen hat Gustav Hunger. Draußen läuft er schnell voraus. Papa ruft zwar "Achtung!", aber Gustav stürzt über eine Kante. Er will seinen 7. Sinn besser trainieren. Aus der OHRENBÄR-Hörgeschichte: Ich sehe was, was du nicht siehst (Folge 5 von 7) von Katrin Askan. Es liest: Richard Barenberg. ▶ Mehr Hörgeschichten empfohlen ab 6: https://www.ohrenbaer.de/podcast/empfohlen-ab-6.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

Cerramos la serie “Acompañando al CEO” con Juan Antonio Escobedo, experto en transformación cultural y con más de 28 años de experiencia en empresas globales.En este tercer episodio hablamos de un tema clave para la evolución de Recursos Humanos:

Jeden Donnerstag holt Papa Gustav von der Vorschule ab. Dann geht’s ins Schwimmbad. Gustav liebt Wasser. Er geht vor, während Papa zahlt. Oje, wo ist sein Rucksack? Wo ist Papa? Aus der OHRENBÄR-Hörgeschichte: Ich sehe was, was du nicht siehst (Folge 4 von 7) von Katrin Askan. Es liest: Richard Barenberg. ▶ Mehr Hörgeschichten empfohlen ab 6: https://www.ohrenbaer.de/podcast/empfohlen-ab-6.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

Do you know your blood type? When you're pregnant, the Rh factor in your blood type is important because it could conflict with the baby's blood type. What determines a baby's blood type and Rh factor? At what point during your pregnancy can their blood type be determined? And how will your pregnancy change if your baby's blood is incompatible with your own?  Learn more about your ad choices. Visit megaphone.fm/adchoices

Can 4 Volts of Electricity Replace 60 Bars of Pressure in Seawater Desalination? ilion Water Technologies is a 2025 spinout from the Physics Laboratory of the École Normale Supérieure in Paris. Their VIRO (Voltage-Induced Reverse Osmosis) technology claims to replace the high-pressure pump train in seawater desalination with an alternating electric field applied to engineered composite membranes, operating at atmospheric pressure.

Im Morgenkreis in der Vorschule hört Gustav sofort, dass ein Neuer da ist: Lukas, der Praktikant. Die blinden Kinder erzählen ihm, wie sie sehen: mit Ohren, Händen und Nase. Aus der OHRENBÄR-Hörgeschichte: Ich sehe was, was du nicht siehst (Folge 3 von 7) von Katrin Askan. Es liest: Richard Barenberg. ▶ Mehr Hörgeschichten empfohlen ab 6: https://www.ohrenbaer.de/podcast/empfohlen-ab-6.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

Der Schulbus ist da. Gustav trifft dort seine Freundin Agneta, die vor ihm abgeholt wurde. Sie ist auch blind. Sie bemerkt sofort, dass er nicht gekämmt ist. Er erzählt von den Spatzen. Aus der OHRENBÄR-Hörgeschichte: Ich sehe was, was du nicht siehst (Folge 2 von 7) von Katrin Askan. Es liest: Richard Barenberg. ▶ Mehr Hörgeschichten empfohlen ab 6: https://www.ohrenbaer.de/podcast/empfohlen-ab-6.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

Als Gustav morgens aufwacht, hört er die Spatzen. Gustav ist blind. Für ihn ist es normal, dass er nicht mit den Augen sehen kann. Die Spatzen will er gleich füttern. Er weiß auch, wie. Aus der OHRENBÄR-Hörgeschichte: Ich sehe was, was du nicht siehst (Folge 1 von 7) von Katrin Askan. Es liest: Richard Barenberg. ▶ Mehr Hörgeschichten empfohlen ab 6: https://www.ohrenbaer.de/podcast/empfohlen-ab-6.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

Das sind gewöhnliche Tage im Leben eines recht ungewöhnlichen Jungen: Gustav wird zur Vorschule gebracht, fährt mit dem Vater ins Schwimmbad, spielt zu Hause mit einer Freundin. Gustav ist blind. Für ihn ist es normal, dass er nicht mit den Augen sehen kann. Manche Stolperfalle gibt es, weil auch er einfach seine Grenzen austestet – wie alle Kinder. Alle 7 Folgen der OHRENBÄR-Hörgeschichte: Ich sehe was, was du nicht siehst von Katrin Askan. Es liest: Richard Barenberg. ▶ Mehr Hörgeschichten empfohlen ab 6: https://www.ohrenbaer.de/podcast/empfohlen-ab-6.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

Hört Tante Mila wirklich nicht mehr gut? Sie sagt nein. Mama, Papa und Ron sagen ja. Luzie begleitet ihre Tante zum Arzt. Wie wär’s mit einem roten Hörgerät? Als Überraschung! Aus der OHRENBÄR-Hörgeschichte: Tante Mila macht Geschichten (Folge 7 von 7) von Monika Feth. Es liest: Eva Mattes. ▶ Mehr Hörgeschichten empfohlen ab 4: https://www.ohrenbaer.de/podcast/empfohlen-ab-4.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

Coordonner 100 personnes… à 4 000 mètres d'altitude. En chute libre. Avec une obligation de 100 % de réussite.Ça fait peur ? C'est le travail de Domitille Kiger, championne du monde de freefly et organisatrice de multiples records du monde en grandes formations. Son terrain de jeu ? Des figures géantes construites en plein ciel, parfois à plus de 70 personnes, où chaque erreur peut tout faire échouer. Un peu un laboratoire grandeur nature du management en conditions extrêmes finalement.Que vous soyez manager, DRH ou dirigeant, vous trouverez dans cet épisode des parallèles très concrets avec vos enjeux quotidiens : coordination, feedback, gestion de crise, décision en incertitude, dynamique collective…Bonne écoute !À très vite,Prenez soin de vous !Plus d'info :Pour suivre Domitille sur LinkedIn : https://www.linkedin.com/in/domitille-kiger-conferenciere/Pour recevoir gratuitement notre sélection hebdo de conseils pratiques pour animer votre équipe, rendez-vous ici : https://teambakery.com/nlEt n'oubliez pas de laisser 5 étoiles et un gentil commentaire sur Apple Podcast et Spotify si l'épisode vous a plu.CHAPITRAGE00:00:00 - Intro00:03:09 - Présentation de Domitille et son parcours00:09:40 - Comment a-t-elle découvert le saut en parachute à 15 ans ?00:12:14 - Comment se prépare-t-elle en tant que championne du monde ?00:14:34 - Se préparer aux sauts en équipes00:26:28 - Dire non à quelqu'un de son équipe00:29:14 - Y a-t-il un profil type des gens de son équipe ?00:31:00 - Comment font-ils leurs feedbacks ?00:35:57 - La notation dans le sport00:39:34 - Ce que les managers peuvent directement adopter dans leur quotidien00:49:39 - Son process de décisionVous aimerez cet épisode si vous aimez : Outils du Manager • Happy Work • HBR on Leadership • Le Podcast de la Formation • MANAGEMENT & LEADERSHIP • Learn & EnjoyHébergé par Audiomeans. Visitez audiomeans.fr/politique-de-confidentialite pour plus d'informations.

Tante Mila wollte zum Mittagessen kommen. Doch nun sagt sie ab. Luzie bringt ihr Essen nach Hause. Sie staunt: Tante Mila hat eine Mäuseleiter gebaut, um ein Mäuschen zu retten. Aus der OHRENBÄR-Hörgeschichte: Tante Mila macht Geschichten (Folge 6 von 7) von Monika Feth. Es liest: Eva Mattes. ▶ Mehr Hörgeschichten empfohlen ab 4: https://www.ohrenbaer.de/podcast/empfohlen-ab-4.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

Goldfisch Iwan ist krank! Sofort eilt Luzie zu Tante Mila. Sie gehen zum Tierarzt und der kann helfen. Kaum ist Iwan zu Hause ins Aquarium gesetzt, feiern sie ein Willkommensfest! Aus der OHRENBÄR-Hörgeschichte: Tante Mila macht Geschichten (Folge 5 von 7) von Monika Feth. Es liest: Eva Mattes. ▶ Mehr Hörgeschichten empfohlen ab 4: https://www.ohrenbaer.de/podcast/empfohlen-ab-4.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

Tante Mila will mit Luzie ins Kino gehen. Sie hat Karten für einen Kinderfilm geschenkt bekommen. Tiere sind dort nicht erlaubt. Können sie Hund Othello heimlich einschmuggeln? Aus der OHRENBÄR-Hörgeschichte: Tante Mila macht Geschichten (Folge 4 von 7) von Monika Feth. Es liest: Eva Mattes. ▶ Mehr Hörgeschichten empfohlen ab 4: https://www.ohrenbaer.de/podcast/empfohlen-ab-4.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

Continuamos la serie “Acompañando al CEO” con Juan Antonio Escobedo, experto en transformación cultural y con más de 28 años de experiencia en empresas globales.En el episodio anterior hablamos del rol estratégico de Recursos Humanos junto al Director General.En esta segunda conversación exploramos otro ángulo fundamental: la relación entre RH y las áreas operativas como Producción o Calidad.En muchas organizaciones existen juicios y tensiones hacia Recursos Humanos, especialmente porque es el área asociada a contratar, evaluar o despedir personal. Pero el rol de RH va mucho más allá de esos momentos.En este episodio reflexionamos sobre:​ Cómo debería relacionarse un líder de Producción o Calidad con la dirección de Recursos Humanos​ Qué papel juega RH dentro del staff directivo​ Por qué surgen malos entendidos entre las áreas​ Y cómo construir una colaboración más estratégica para el bienestar de las personas y el negocioUna conversación útil para líderes que quieren comprender mejor el papel de Recursos Humanos dentro de la organización.

Dr. Don and Professor Ben talk about the risks from drinking wine from grapes grazed by goats. Dr. Don - not risky

Als Luzie ihre Tante Mila heute besucht, ist die Wohnung ganz durcheinander. Tante Mila hat bald Geburtstag. Darum bastelt sie sich selbst ein Geschenk: ein Vogelhaus mit Gardinen. Aus der OHRENBÄR-Hörgeschichte: Tante Mila macht Geschichten (Folge 3 von 7) von Monika Feth. Es liest: Eva Mattes. ▶ Mehr Hörgeschichten empfohlen ab 4: https://www.ohrenbaer.de/podcast/empfohlen-ab-4.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

Einmal im Monat fährt Tante Mila in die Stadt. Dann macht sie sich chic. Und Luzie darf sie begleiten. Obwohl es regnet, haben sie viel Spaß mit Himbeerbonbons und Orgelspiel. Aus der OHRENBÄR-Hörgeschichte: Tante Mila macht Geschichten (Folge 2 von 7) von Monika Feth. Es liest: Eva Mattes. ▶ Mehr Hörgeschichten empfohlen ab 4: https://www.ohrenbaer.de/podcast/empfohlen-ab-4.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

Tante Mila ist Omas Schwester. Manche Leute finden sie wunderlich. Aber Luzie nicht! Sie freut sich, denn heute kommt Tante Mila zu Besuch. Und Mama backt extra Möhrentorte. Aus der OHRENBÄR-Hörgeschichte: Tante Mila macht Geschichten (Folge 1 von 7) von Monika Feth. Es liest: Eva Mattes. ▶ Mehr Hörgeschichten empfohlen ab 4: https://www.ohrenbaer.de/podcast/empfohlen-ab-4.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

Tante Mila ist Omas Schwester. Ihr Haus unten im Dorf ist alt und vollgestopft mit Dingen, die Geschichten erzählen. Das Gartentörchen hängt schief in den Angeln. Türen und Fenster stehen meistens offen. Tante Milas Lieblingsfarbe ist Rot und in ihrem Aquarium wohnt ein Prinz. Manche Leute finden sie wunderlich. Luzie nicht! Sie hat Tante Mila einfach nur lieb. Alle 7 Folgen der OHRENBÄR-Hörgeschichte: Tante Mila macht Geschichten von Monika Feth. Es liest: Eva Mattes. ▶ Mehr Hörgeschichten empfohlen ab 4: https://www.ohrenbaer.de/podcast/empfohlen-ab-4.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

durée : 00:13:04 - Les Enjeux internationaux - par : Guillaume Erner - Dans les années 1920, des rescapés du génocide arménien trouvent refuge en France… Une partie d'entre eux s'installe dans la Drôme et notamment à Valence, où se constitue progressivement une véritable "petite Arménie". Quelle influence cette immigration a-t-elle eue sur la ville et la région ? - réalisation : Félicie Faugère - invités : Jean-Luc Huard Historien, auteur de "Présence arménienne en Rhône-Alpes : histoire d'une communauté"

Herr Li Tai-bo singt ein Lied. Währenddessen gibt der Gelbe Hase Gabriele aus dem Kessel zu trinken. Das schmeckt wie Musik. Plötzlich versteht Gabriele alles. Da wacht sie auf. Aus der OHRENBÄR-Hörgeschichte: Gabriele in der gelben Zeit (Folge 7 von 7) von Fritz Mikesch. Es liest: Peter Simonischek. ▶ Mehr komplette Hörgeschichten gibt es hier: https://www.ohrenbaer.de/podcast/komplette-hoergeschichten.html ▶ Mehr Hörgeschichten empfohlen ab 6: https://www.ohrenbaer.de/podcast/empfohlen-ab-6.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

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Nun haben Gabriele und der Papierdrache nicht nur den Gelben Hasen kennengelernt, sondern auch den chinesischen Dichter. Der singt und die Prinzessin hat Durst. Aus der OHRENBÄR-Hörgeschichte: Gabriele in der gelben Zeit (Folge 6 von 7) von Fritz Mikesch. Es liest: Peter Simonischek. ▶ Mehr komplette Hörgeschichten gibt es hier: https://www.ohrenbaer.de/podcast/komplette-hoergeschichten.html ▶ Mehr Hörgeschichten empfohlen ab 6: https://www.ohrenbaer.de/podcast/empfohlen-ab-6.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

C dans l'air du 4 mars 2026 - Iran : la France entrainée dans la guerre ?Au cinquième jour de guerre au Moyen-Orient, l'armée israélienne poursuit ses tirs sur l'Iran et intensifie ses bombardements au Liban. Les États-Unis revendiquent, eux, des frappes « sur près de 2 000 » cibles depuis samedi. Mais la République islamique d'Iran résiste à la puissance de feu des États-Unis et d'Israël. Des drones frappent les ambassades américaines de la région, mais aussi les pays du Golfe, alliés de Washington, ainsi que des navires dans le détroit d'Ormuz. Les Gardiens de la révolution disent en avoir le contrôle total ce mercredi.Parallèlement, les autorités iraniennes ont annoncé le report de l'hommage national à Ali Khamenei, initialement prévu ce mercredi soir à Téhéran, alors que plusieurs frappes américaines et israéliennes ont eu lieu contre l'Assemblée des experts, chargée notamment d'élire un nouveau guide suprême.Alors, jusqu'à quand le régime des mollahs peut-il tenir ? La Turquie, qui avait exprimé ces derniers jours son inquiétude face aux attaques américano-israéliennes contre l'Iran, « déclenchées par des provocations du Premier ministre israélien Netanyahu », a mis en garde ce mercredi Téhéran après qu'un tir de missile balistique visant son espace aérien a été détruit par « les éléments de défense aérienne et antimissile de l'OTAN » déployés en Méditerranée orientale. La Turquie « n'était pas la cible du missile », a précisé en début d'après-midi un responsable turc à l'AFP. « Nous pensons qu'il visait une base militaire » à Chypre, « mais qu'il a dévié de sa course », a-t-il ajouté.La France, de son côté, a décidé de renforcer son dispositif militaire dans la région, alors que le rapatriement des ressortissants français a commencé. Le porte-avions Charles-de-Gaulle fait route vers la Méditerranée, a ainsi annoncé le chef de l'État mardi soir lors d'une allocation télévisée. Une frégate, le « Languedoc », est arrivée, elle, au large de Chypre dès hier soir, et des moyens de défense antiaérienne supplémentaires vont être envoyés pour sécuriser ce pays membre de l'Union européenne, « avec lequel nous venons de signer un partenariat stratégique », et où des drones iraniens ont visé une base britannique, a indiqué le président de la République. La première frappe avait suivi de peu l'annonce par le Premier ministre britannique, Keir Starmer, qu'il avait autorisé les États-Unis à utiliser les bases britanniques dans sa campagne militaire contre l'Iran.Alors, quelle est la situation au Moyen-Orient ? Pourquoi Chypre se retrouve-t-elle impliquée dans le conflit ? La France est-elle entraînée dans cette guerre ? Enfin, quels sont les pays engagés dans une démarche de « dissuasion nucléaire avancée » avec la France ? Nos journalistes ont eu accès à la base aérienne stratégique d'Istres, dans les Bouches-du-Rhône, qui abrite l'arme nucléaire française.Experts : - Général Dominique Trinquand - Ancien chef de la mission militaire française auprès de l'ONU, auteur de D'un monde à l'autre- Melissa Bell - Journaliste, correspondante à Paris pour CNN- Alain Pirot - Journaliste, spécialiste des questions de défense- David Rigoulet-Roze - Politologue – Chercheur associé à l'Institut français d'analyse stratégique- Magali Lacroze, journaliste #cdanslair (en duplex de Tel Aviv)

Beloved, Scientifically, we only access about 1% of the light spectrum and frequency bands. We call this "real," but it is only a fraction of what exists.While this may be FAR LEFT FIELD as you read this - it would be irresponsible of me NOT to share - in the month's ahead.Aliens, UFO's and what's ahead.RIGHT NOW WE ARE WITNESSING….Government secrecy is crumbling as its costs exceed the risks of transparency.Instead of chaos or Hollywood-style invasions, world leaders, scientists, and the media will gradually normalize extraterrestrial presence.This shift is less about seeing ships in the sky and more about a fundamental identity change—moving from cosmic isolation to realizing we've never been truly alone.The Big PictureWhat's Actually Happening Something remarkable is occurring at the cellular level of every human being on Earth right now. While spiritual communities have long discussed “DNA activation” and “ascension,” there's actually a fascinating interplay between cosmic physics and human biology driving these changes.The Science Behind the construct of the “Veil Thinning”Our sun creates something called a heliosphere - essentially a protective bubble that extends beyond our solar system. This barrier has historically filtered out much of the cosmic radiation and light particles coming from the rest of the galaxy.Fear is the primary anchor that keeps consciousness locked in the body. When the body starts to "shut down" during deep meditation or an exit, the ego panics. Letting go of the fear of other dimensions or of dying - is actually the key to truly living and exploring the beyond.Here's what's changing:* The sun itself is transforming - becoming whiter and brighter than previous decades* The heliosphere is becoming more permeable, allowing more interstellar particles through* Earth's gravitational field is also shifting, permitting more of these “light codes” to reach us* These aren't mystical concepts - they're measurable electromagnetic frequenciesWhat This Means at the Cellular LevelAccording to channeled information - the energies are interacting with our biology in specific ways:The Telomere Connection: The telomeres (protective caps at the ends of our chromosomes) are allowing electromagnetic frequencies to pass through the DNA coils. This is triggering genetic expressions that have been dormant - essentially “remembering” capabilities that were switched off long ago.Mitochondrial Changes: The energy-producing structures in our cells are adapting. The suggestion is that eventually, human cells will be able to hold light directly, potentially reducing our dependence on food for energy.Why We Feel So Tired: The fatigue many people experience isn't random. When these cosmic frequencies interact with our cellular structures, it creates a kind of beneficial stress - similar to how a sauna creates stress proteins that ultimately strengthen the body. Our systems are working overtime to integrate these new frequencies.Ascension Symptoms - not just for EmpathsExplained…..Many people report experiencing:* Chronic fatigue and disrupted sleep patterns* Heart palpitations* Ringing in the ears* Skin issues and sensitivities* Watery eyes* Feeling mentally “scattered” or anxiousYour body is literally acting as a conduit - pulling cosmic energy down through your personal energy field, processing it through your cells, and anchoring it into Earth's crystalline grid system. Where you have emotional, mental, or energetic blockages, this energy has to push through, creating discomfort.Why some people feel it more than others: It depends on where you are in relation to what's called “the singularity” - a convergence point of timelines:* Those “ahead” of it feel energized and clear* Those “in the middle” experience neutral observation* Those “behind” it feel heavy, sluggish, and lost* Earth is a “Free Will Planet”The Bigger Context? You Chose It. Earth holds a unique position in our galaxy as a free will zone. This means:* We've been largely left alone to develop and make our own choices* That changed with nuclear weapons - when the bombs dropped on Hiroshima and Nagasaki, the effects rippled through quantum fields across the universe, affecting beings everywhere* This triggered intervention - not control, but assistance from various cosmic intelligences who recognized that “the children found the matches”The Living Library ConceptThrough my experience as a intuitive and Akashic Reader, just as the astral has a library of resonance - the Earth is also a “living library” - for every animal species on this planet, there exists an extraterrestrial race that resembles it. This planet was seeded with incredible biodiversity as a kind of cosmic repository.The Hybridization ProgramsThere are ongoing programs creating human-extraterrestrial hybrid children. Some live on ships, others on Earth. The purpose isn't sinister - it's about creating beings who can be a genetic and frequency match for where Earth is heading, since not all current humans will be able to adapt to the higher frequencies.The Timeline We're InWe're currently about 75-78% through an 18-year window (2012-2030) that represents the most significant consciousness expansion in human history.Key markers “suggested”* 1987 (Harmonic Convergence): The starting gun for this shift* 2012: Earth/Gaia herself ascended; karmic laws that had been held in the grids were released* 2025: A year of pushing through density and difficulty - necessary preparation* 2026: A “one year” in numerology - about renewal, not repair; what we create this year sets the cycle for where we're heading through 2030* 2030: The completion of this particular ascension windowThe 3D/5D SplitRather than everyone moving to “5D” as a destination, what's actually happening is more nuanced:* Multiple dimensions exist simultaneously (it's called “multi-dimensional” for a reason)* We fluctuate through various density perspectives constantly* The 3D and 5D “timelines” are being pulled apart - people will increasingly experience very different realities based on their frequencyThe Human Hybridization HistoryOur DNA carries contributions from multiple cosmic sources:The Anunnaki (approximately 350,000 years ago): The primary encoders who created a significant jump in human evolution. They contributed what's called “Enki's gift” - dormant potential in our DNA that's now reactivating. RH negative blood is Anunnaki blood, which explains why RH negative women sometimes have difficulty conceiving - that blood carries programming that resists mixing with the standard human genome.The Pleiadian's contributed quantum aspects to our chromosomes.It's why we process in 12's and 24's. This isn't arbitrary - it's genetic encoding from these cosmic ancestors that determines how we can perceive dimensional realities. Currently, we can only process up to 12 dimensions; expanding beyond that will take approximately 3,000 more years of evolution.Practical Wisdom for Navigating This TimeHOW IT EFFECTS OUR NERVOUS SYSTEM AND MENTAL HEALTHWhen powerful energy waves hit Earth, many people experience anxiety spikes. Here's why:The brain's synapses can't always handle the acceleration of these frequencies. When the mind can't process what's happening, it spirals into fear responses - “I'm being attacked,” “something terrible is happening.” This creates anxiety that feels sourceless.The solution?Self compassion and for the love of God, get off social media. Ground yourself. Stay in your heart rather than your head. The heart processes feeling and compassion; the mind processes logic and fear. During intense energy periods, the heart is your anchor.The Self-Love ParadoxTrue self-love isn't “love and light” without boundaries. That's actually toxic because it:* Doesn't create self-worth* Doesn't allow you to know yourself* Avoids the necessary work of integrationReal self-love means:* Discovering the parts of yourself you've rejected* Learning to love what you've pushed into shadow* Integrating these aspects* Setting firm, compassionate boundaries with othersThe Awakening TruthAwakening isn't awakening to love and light - it's awakening to your trauma. You cannot skip straight to being an “ascended being” without walking through all your density. There are no shortcuts. You have to run the marathon.Key Principles for This Time* Go within, not without - All answers exist inside you. External teachers and resources are helpful, but they're not necessary if you can access your own inner knowing.* Feel, don't think - You don't think energy; you feel it. The ego wants timelines and logic; source wants to guide you through feeling and authenticity.* Surrender, don't trust - Trust is conditional (”I'll do my part if you do yours”). Surrender is unconditional allowing.* Internalize, don't externalize - Stop projecting onto external mirrors. Learn from what life shows you by looking inward.* Stay in compassionate detachment - Observe without judgment. Detach without disconnecting.* Release victimhood - The belief that “rogue aliens did this to us” or “we have no free will” is the ego avoiding responsibility. Starseeds and lightworkers are just as powerful as any cosmic being - they simply don't believe it yet.The Deeper MeaningThe purpose of this entire journey? To allow source - your higher self, your soul - to work through you in a state of non-resistance, creating healing and synchronicity for yourself and everything around you.We're not just passive recipients of cosmic change. We're active participants in ascending a planet - something that's never been done quite this way before.The “great experiment” is seeing if a free-will planet can raise its consciousness collectively, and we're well ahead of schedule.The work isn't easy. It requires releasing everything built from fear, trauma, and conditioning. It means becoming unrecognizable to those who knew the old version of you. It often means losing relationships that can't match your new frequency.But it's also the most profound opportunity any soul could choose - to be here, now, participating in this transformation.Stay in your hearts. Where your heart is, where your feeling is, where your compassion is - that's where we save each other. I truly believe every single soul here without question becomes free.Love, KassandraPS: If this lit up your heart and mind to go deeper into infinite love, then I'd love for you to experience the LIGHT BETWEEN ORACLE. Five Guides and a Five Layer Path…..The Five-Layer Path integrates intention rituals, intuitive card draws, ancient wisdom teachings, somatic practices, and multidimensional exploration to support your journey. With your purchase, you gain access to:* Tailored Guidance: Personalized oracle readings to answer your questions.* Your Place of Power: Tools to discover and transform disempowering states.* Self Hypnosis: Techniques to rewire the subconscious, enhanced by the Neuro-Nature Self Hypnosis App.* Soul Prayer: Contemplative practices to deepen your connection to inner wisdom.* Poetic Insights: A space to save reflections for creative expression and meaning.* Five-Layer Path for Integration: A holistic approach combining intention, intuition, ancient teachings, somatic practices, and multidimensional awakening.This journey helps you:* Gain Clarity: Understand what matters most and take meaningful action.* Reduce Self-Doubt: Reframe fear and confusion into empowering patterns.* Reconnect with Inner Wisdom: Strengthen your intuitive guidance.* Release Emotional Blocks: Heal through co-regulation and emotional release.* Enhance Creativity: Ignite new perspectives and creative expression.* Cultivate Mindfulness: Ground your energy and deepen your inner connection.* Navigate Life's Challenges: Approach obstacles with confidence and insight.* Transform Your Life: Embrace personal power and align with your larger vision.In essence, The Light Between Oracle Journey is a transformative framework that draws out your inner wisdom, guiding you to align with your personal power and purpose through the support of unique points of view with the playful integrity of the Chakra Centers, Universal Laws, Subtle Energy Bodies, Elements of Nature, and Circuits of Emotion. Want to be mind blown? Tap into my friends interview HERE! This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit thelightbetween.substack.com/subscribe

Gabriele und der Papierdrache sind gelandet. Der Gelbe Hase begrüßt sie vor seiner achteckigen sonnengelben Hütte. Was hat der chinesische Dichter mit allem zu tun? Aus der OHRENBÄR-Hörgeschichte: Gabriele in der gelben Zeit (Folge 5 von 7) von Fritz Mikesch. Es liest: Peter Simonischek. ▶ Mehr komplette Hörgeschichten gibt es hier: https://www.ohrenbaer.de/podcast/komplette-hoergeschichten.html ▶ Mehr Hörgeschichten empfohlen ab 6: https://www.ohrenbaer.de/podcast/empfohlen-ab-6.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

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Dr. Deb Muth 0:00 Welcome back to Let’s Talk Wellness Now. I’m your host, Dr. Zab, and we are continuing our discussion this week on 0:08 peptides. And so, if you haven’t heard our first conversation about peptides, 0:13 please go back and look at that episode. We talk all about the manufacturing, the safety, the quality of peptides, and we 0:20 dove into GLP1s. And today we’re going to dive into peptides for sexual 0:26 wellness, immune function, growth hormone, and all the amazing fun things 0:32 we can do with peptides. So, as usual, grab your cup of coffee or tea, settle 0:37 in, and let’s talk wellness now. And we’re going to take a short pause from our sponsor. I know we’ve got to do 0:44 that, you guys. They’re who keep us on the air. So, I’m going to pause for just a minute and be right back after this 0:50 message from our sponsor. Ladies, it’s time to reignite your vitality. Primal 0:56 Queen supplements are clean, powerful formulas made for women like you who want balance, strength, and energy that 1:03 lasts. Get 25% off at primal queen.com. Serenity Health. That’s primalqueen.com. 1:10 Serenity Health. Because every queen deserves to feel in her prime. All 1:15 right, everybody. We are back. And are you ready? We are talking all things peptide and I am opening the show today 1:23 with sexual wellness. Yes, I’m going there, you guys. I am going there. You 1:29 know, this has really become a big issue for people um of all ages. It’s not just 1:3 4us older people. It’s younger people, too. And there’s a whole variety of reasons why we have sexual dysfunction. 1:42 And when we’re talking about sexual dysfunction, we’re not just talking about it doesn’t work, right? Or I can’t 1:48 reach orgasm. A lot of it is around desire and um the thought of it and 1:54 wanting to connect, wanting to be kinder to one another, wanting to be touching 2:00 one another. A lot of it resolves or revolves around that. And so there are some peptides that can help us and I’m 2:08 really excited to be able to talk about those today. So the first one is called PT-141. 2:14 This targets the brain not the periphery. Right? So for many women I 2:20 will always tell you sex starts between here. It is a brain thing for us. It is 2:26 not necessarily a physical thing. For guys that’s a little different. It’s very physical. For women it’s all in our 2:32 brain. So tip for you men that are listening. You have to prime your woman’s brain first if you want her to 2:38 have sex with you that night. You have to be nice to her. You have to bring her flowers. Do the dishes for her. Do 2:45 something kind. Bring her a cup of coffee or tea or a glass of wine. Take her to dinner. You have to woo her. And 2:51 I don’t care how long you’ve been married. That has to happen. And tip number two, don’t say anything stupid 2:57 that day. I’m just being honest. When you guys say things that make us upset, 3:03 that lingers with us for the rest of the day. And it’s it’s a turnoff for us. And 3:08 for a lot of women, we can’t get past that when it comes time to snuggle at night. And sex doesn’t always have to be 3:14 at night either. So, you can tell I really love talking about this conversation, but we’re going to get into the peptide part of it because this 3:21 is going to help people. So, um, PT-141 is marketed as I’m going to slaughter 3:28 this name, Vali, and it represents a fundamentally different approach to 3:34 sexual dysfunction than the PDE5s inhibitors like Slenden, Viagra, 3:40 Tedataphil, which is Seialis. And while the PDE5 inhibitors work specifically by 3:47 enhancing blood flow to the genital tissues, PT-141 works centrally in the brain by 3:54 modulating neural s neural circuits involved in the sexual desire and 4:00 arousal. Now PT-41 is a cyclic hpatipeptide. It’s seven amino acid 4:07 peptide arranged in a cyclic structure that acts as a melanoortin receptor 4:13 agonist and with particularly the infinity for MC3R and MC4R subtypes. 4:20 It’s actually a metabolite of the melanotan 2, a peptide originally 4:26 developed for tanning that was also found to enhance sexual desire in early 4:31 studies. Now the melanoortin system in the brain is involved in multiple functions including energy homeostasis 4:39 but it also is involved in sexual motivation and arousal behaviors. The FDA approved PT-141 in 2019 specifically 4:48 for the treatment of acquired generalized hypoactive sexual desire 4:54 HSDD in permenopausal women. So for the first time we have a medication that was 5:01 approved by the FDA to use for women for sexual dysfunction. We have had all of 5:07 these seialis tedataphil viagros for men but we had nothing for women. And so 5:12 this is amazing that this is available for women and approved by the FDA. It’s a big deal. This represents the first 5:19 and only FDA approved medication specifically targeting these circuits of sexual desire rather than the peripheral 5:27 arousal mechanisms. And this indication is quite specific, meaning it was developed at some point, not lifelong. 5:35 So I if you’ve had sexual dysfunction your entire life, this medication was 5:40 not approved for you. But if it’s something that you developed over time, like when you went through pmenopause or 5:46 menopause or some women have this experience happen after childirth, that’s what we’re talking about here. 5:53 Now, it’s also not just um supposed to be used if you dislike your partner, 5:59 right? If your relationship is bad and you dislike your partner, this probably isn’t going to fix a ton. It might help 6:05 a little bit, but that’s not what it’s meant for. So, you really have to know what you’re using it for and why. And 6:11 the other thing that I would say is this is something that we don’t go to if your hormones are not balanced properly. You 6:17 have to balance your hormones properly before using something like this because it still may not work. Now, the only 6:24 caveat to that is if you’re a woman that has a risk of breast cancer and can’t use hormones, then that’s a different 6:31 story and we would have that conversation about whether or not this medication would be appropriate for you. Now, the FDA label specifies PTA1 uh 6:39 PT-141 as it not being indicated for HSDD in causes where low sexual desire 6:46 is due to coexisting medical or psychiatric conditions, problems with relationships, like we had talked about, 6:53 side effects to medications or other substance use. This specifically reflects the importance of differential 6:59 diagnosis. Low sexual desire can have many root causes and PT-41 is only 7:05 appropriate when those causes have been ruled out. Now, I have I used PT41 in 7:10 people who have sexual dysfunction issues as a result of using 7:16 anti-depressants. Yes, I have. I’ve used Flynn in that effect as well. And it 7:21 does work sometimes, but it doesn’t work completely. But you need to know that that is not what the approval is for the 7:27 FDA. So that is done in something that we call off label use. So very important 7:33 to know. Now in these clinical trials leading to FDA approval, this was published by Kinsburg and colleagues in 7:40 obstetrics and gyne gynecology in 2019. PT-141 demonstrated statistically 7:46 significant improvements in sexual desire and decreases in distress related 7:51 to low desire compared to placebo. The effects manifest over 45 minutes to 7:56 several hours after the injection and the mechanisms involved modulation of dopamine and melanoorton pathways in the 8:04 hypothalamus and the brain regions that involved sexual motivation. Now cardiovascular effects of PT 141 require 8:12 careful attention. This drug causes transient increases in blood pressure about 3 to four points and transient 8:20 decreases in heart rate. And because of this, it is contraindicated in patients 8:25 with uncontrolled hypertension or known cardiovascular disease. And it has been studied in patients who’ve had recent 8:32 cardiovascular events or sorry hasn’t been studied hasn’t been studied in patients who’ve had recent 8:39 cardiovascular events. So patients need to have their blood pressures checked before starting therapy. Nausea is 8:45 extremely common. It is one of the biggest things I often will tell people to take an anti-nausea medicine if 8:52 they’re going to do this because the last thing you want to do is inject this medication and think it’s going to give 8:57 you this great time with your partner and you’re so nauseated that you can’t even perform, don’t want to kiss, don’t 9:05 want to do anything. It it can be pretty profound for some people. um it does affect about 40% of the patients in 9:12 clinical trials which is why many clinicians require or recommend an 9:17 anti-nausea medication like I had just said other common adverse effects include flushing injection site 9:24 reactions headache in about 13% of the population which I have seen worse if 9:30 people are prone to headaches and the headaches are pretty intense so I will also have them premedicate if they have 9:36 that um sensitivity ity with a Tylenol or Advil, Alie, whatever it is they 9:42 typically use for their headaches to help prevent that from occurring. Now, some patients also experience a 9:50 generalized hyperpigmentation of their skin, particularly in areas with chronic friction, and this may not be reversible 9:57 after discontinuation. So from an integrative perspective, PT-41 10:03 represents one tool in addressing female sexual dysfunction, but it should never be the first or only intervention. And 10:11 low sexual desire in women is complex. Multiffactorial involving hormonal imbalances, low testosterone, estrogen 10:18 deficiency, progesterone imbalances, thyroid dysfunction, adrenal dysfunction, and with elevated or 10:24 disregulated cortisol levels, sleep deprivation, relationship issues, unresolved trauma, including sexual 10:31 trauma, chronic pain, body image concerns, and medication side effects such as SSRIs are notorious for this. So 10:39 a comprehensive hormone panel including total and free testosterones, estradile, 10:45 progesterone, DHEA, thyroid function in cortisol assessment, ideally four-point 10:51 cortisol, salivary should precede any pharmacological intervention. And additionally, addressing the 10:57 psychological component and relationship dimensions through appropriate therapy is necessary. I have a lot of patients 11:03 that say, “This is just too much work for sex. I don’t want the side effects. I don’t want to deal with this.” and that’s totally fine. But for some 11:09 people, their sexual dysfunction is actually causing more problems on their 11:14 relationship and they want to do something to fix that. And just know that if you’re using a peptide like this 11:20 that comes with some of these side effects and you have to premedicate for it, it is not the end of the world. Um, 11:27 but it may be a possibility that you may need that. So, let’s dive into body composition and growth hormone access. 11:34 So Tesmarellin is the only FDA approved GH 11:40 analog. Tesarelin is marketed as Agrifta and Agria SV. It is a synthetic analog 11:48 of human growth hormone releasing hormone. So GH RH human growth hormone 11:53 releasing hormone. These things are such long names it’s confusing and it’s difficult to spit out, right? It 11:59 consists of 44 amino acids. The structure is identical to our own 12:05 body’s growth hormone GHR um with the addition of trans3 hexonol group which 12:14 stabilizes the molecule that extends its half-life compared to the native GHR. 12:19 The mechanism of tesmarellin is elegant in its preservation of physiological 12:24 growth hormone GH secretion patterns and rather than administering an exogenous 12:30 growth hormone directly, tesmarillin binds to the GH receptor in the anterior 12:36 pituitary gland stimulating the indogenous pulsatile release of GH. So 12:42 you know it it’s slower in that stimulation and it pulsates instead of a direct rise and fall. This pusile 12:49 pattern more closely mimics natural GH secretion which occurs in bursts 12:54 primarily during sleep. The GH then stimulates the liver to produce insulin-like growth factor IGF-1 which 13:01 exerts many of the downstream metabolic effects including lipolytic effects on 13:07 the atapost tissue. So fat atapose and how we break that down. The FDA approved 13:13 tesmarellin in 2010 for a very specific narrow indication, the reduction of 13:19 excess abdominal fat in HIV infected patients with lipodistrophe. This 13:25 condition characterized by abnormal fat redistribution with accumulation of visceral body fat and the loss of 13:32 subcutaneous fat in face and limbs developed as a complication of an 13:37 antiviral therapy particularly with older protease inhibitor reg uh 13:42 regimens. The visceral fat accumulation in patients is not just cosmetic. It’s associated with increased cardiovascular 13:49 risk, insulin resistance, and inflammatory markers. The pivotal trial that led to the FDA approval included 13:56 work by Stanley and colleagues published in the annuals of internal medicine in 2014. It demonstrated that tesmarillan 14:03 significantly reduced the visceral atapose measured by CT scan by approximately 15 to 20% which is a 14:10 significant difference to placebo over a short period of time only 26 weeks. Now, 14:16 interestingly, the total body uh weight typically remained stable or even 14:21 increased slightly as the reduction of visceral fat was sometimes offset by increases in lean body mass or 14:28 subcutaneous fat. This highlights an important point. Tesmearellin is not a weight loss drug in its conventional 14:34 sense. Its effects are specifically on body composition and fat redistribution. 14:40 Now the glucose metabolism effects of tesmarellin do require careful monitoring because GH and IGF1 can 14:47 induce insulin resistance. Tesmearellin can increase glucose levels and hemoglobin A1C and in these clinical 14:54 trials glucose tolerance and new onset diabetes occurred in some patients. So 14:59 this creates a therapeutic paradox while res reducing visceral fat we should theoretically improve metabolic health. 15:07 The GH mediated insulin resistance can worsen the glycemic control and patients 15:12 with diabetes require particularly close monitoring. The potential need for adjustment in diabetic medications can 15:19 occur. So I already know what you guys are thinking. Can I use Tesmarellin and 15:24 GLP1 at the same time? And the answer is yes. Especially in those people that we 15:30 know have an insulin resistance already or are prone to that, we can use lowd 15:36 dose micro doing GLP-1 along with tesmarellin to help prevent this from 15:42 occurring um or reduce the risk of it occurring. Now there are some other adverse related problems to growth 15:49 hormone access which include fluid retention which can uh manifest as uh 15:55 ankle swelling, joint pain, muscle pain, paristhesas, carpal tunnel syndrome is 16:01 common to see. Of course you can always see injection site reactions reported about 26 to 30% of the time in the trial 16:08 participants. And this also theoretically has a concern about IGF-1 elevation potentially promoting 16:14 malignancy through long-term data is limited. So we have to be cautious about 16:20 this but it is a growth hormone and anything that is a growth hormone can cause cells to grow and it cannot 16:26 necessarily differentiate between healthy cells and bad cells. So the drug is contraindicated is contraindicated in 16:33 patients with active cancer and in patients with the disruption of the HPA access from conditions like pituitary 16:40 tumors, pituitary surgery, head of radiation um and traumatic brain injury. 16:46 Now off label use of tesmarellin for general anti-aging or body composition 16:51 optimization in non-HIV population, it doesn’t have FDA approval. There is no 16:58 FDA studies. um that promote this, but practitioners do prescribe it for these 17:04 purposes under an experimental and not supported by FDA approved indications. 17:10 And um from an integrative medical standpoint, optimizing natural growth 17:15 hormone secretion through lifestyle interventions, high quality sleep is important. GH primarily is excreted 17:22 during sleep and deep sleep waves. So improving your deep sleep is important. Intermittent fasting can also increase 17:28 growth hormone by five-fold as demonstrated in a Hartman and colleagues uh study from the journal of clinical 17:35 endocrinology and metabolism in 1992. And highintensity interval training, adequate dietary protein, blood sugar 17:42 control, these all can help naturally increase your growth hormone. So, let’s 17:47 dive in now and talk about bone health. peptide hormones um such as oh I’m gonna 17:54 I’m gonna really slaughter this name. Terraparatide is a true bonebuilding 18:01 peptide. It’s marketed as forio. It’s a recumbent form of the first 34 amino 18:08 acids out of 85 of the human parathyroid hormone PTH. It represents a unique 18:13 approach to osteoporosis treatment because it’s one of the few truly anabolic anabolic bone therapies meaning 18:21 it actively binds new bone rather than simply preventing bone loss. The biology 18:26 of parathyroid is fascinating and seemly contraindicated or uh contradictory. 18:32 Continuously sustained elevations of PTH as occurs in hyperarathyroidism 18:37 is catabolic to bone. So people who have hyperarothyroidism typically have significant bone loss 18:44 especially before it’s diagnosed and it causes causes increased bone 18:49 reabsorption loss of bone density increased fracture risk and however 18:55 intermittent exposure to PTH as achieved with once daily uh injections of forio 19:01 has the opposite effect. This intermittent exposure preferentially stimulates osteoblasts bone building 19:08 cells over osteoclasts bone reabsorbing cells and it leads to 19:13 the net bone formation. So terraparatide binds to the PTH receptors on 19:20 osteoblasts and renal tubular cells in bone. It increases the number of 19:25 activity of osteoblasts stimulating the differentiation of osteoblast precursor cells and may 19:32 reduce osteoblast apoptosis basically programmed cell death allowing this bone 19:37 building cell to work longer. The result is increased bone formation, improved bone architecture and tbacular 19:45 connectivity and ultimately increased bone mineral density um particularly in the hip and the spine which is so 19:51 difficult to regain. The FDA approved this medication in 2002 based on pivotal 19:57 studies by Near and colleagues published in the New England Journal of Medicine in 2001 which demonstrated significant 20:05 reductions in vertebral and non-vebral fractures in post-menopausal women with 20:11 osteoporosis. specifically uh reduced new vertebral fractures by 20:17 65% and nonvettebral fragility fractures by 53% 20:23 compared to placebo over a median followup of 21 months. This is really 20:29 incredible because we have not seen this kind of um change uh in other 20:35 medications that we’ve used for osteoporosis. So current FDA approval 20:40 indicates uh this for post-menopausal women with osteoporosis at high risk for 20:46 fracture, men with primary or hypoconatal osteoporosis at high risk for fracture 20:53 and men and women with glucocord cord glucocordide 21:00 induced osteoporosis at high risk for fracture. The high risk qualifier is 21:05 important. uh terrapeptide is reserved for patients with severe osteoporosis, 21:11 multiple fractures, very low low bone density and those who have failed or are 21:16 intolerant of other therapies. The most significant concern for this medication 21:21 is highlighted in a boxed warning with rat toxicology studies where it caused 21:27 osteioaroma which is a bone cancer in a dose dependent and treatment duration dependent manner. The revolence of this 21:34 finding to humans is debated. Rats have fundamentally different bone biology than humans with continuous bone growth 21:41 throughout life and different PTH receptors. Now post marketing 21:46 surveillance in humans hasn’t shown a clear increase in osteocaroma risk but 21:51 theoretically concerns persist and because of this terapeptide is 21:57 contraindicated in patients at risk baseline risk for osteioaroma 22:02 including those with pageantss disease of the bone unexplained elevations of alkaline phosphate prior skeletal 22:10 radiations bone metastases or skeletal malignancies and pediatric patients or young adults 22:16 with open hyes. There’s also a lifetime treatment duration of only 2 years and 22:22 terrapeptide can cause transient hypercalcemia. So an elevated blood calcium and as PTH normally increases 22:31 calcium levels by enhancing bone reabsorption, increasing renal calcium 22:36 reabsorption and promoting activation of vitamin D which increases intestinal calcium absorption. Some patients 22:43 experience orthostatic hypotension within 4 hours of injecting requiring 22:48 caution in at risk populations for blood pressure. Common side effects include 22:53 muscle pain, joint pain, pain in the limbs, nausea, headache, and dizziness. So from an integrative bone health 23:00 perspective, terrapeptides should be part of a comprehensive strategy. Adequate calcium intake, 500 to a,000 23:08 milligrams of calcium a day from food and supplements combined. and vitamin D. 23:13 Getting vitamin D levels of at least 50 to 80 are essential for the drug to work 23:20 optimally. But beyond this, bone health requires vitamin K2, which directs calcium into the bones rather than soft 23:27 tissues, magnesium as a co-actor in bone metabolism, trace minerals like boron, 23:33 copper, silica, and of course, adequate protein intake, which many of us, especially as women, don’t do 0.8 8 to 1 23:42 gram of protein per kilogram of body weight, weightbearing exercise. Of 23:47 course, these all provide mechanical signals that complement the biochemical 23:52 symbol uh signals of terrapeptide. Sequential therapy is also critical. The 23:58 bone mass gains from terraparatide can be lost if patients don’t transition to 24:05 an anti-resorbbitive agent a bisphosphinate after completing this therapy and the anabolic effects to 24:12 build bone but maintaining the new bone requires preventing excess reabsorption. 24:18 So positive things about this but there are definitely some concerns as well. So 24:23 the next one we’re going to talk about is Lu Prolrooide. It is marketed under 24:29 the multiple brand names of Lupron, Depo, Eligard, and it’s a synthetic 24:34 nonapeptide analog of naturally occurring ginonadotropen releasing 24:39 hormone G&R, also called luteinizing hormone releasing hormone, LHR. 24:46 It’s a fascinating example of how manipulating natural hormonal feedback systems can create therapeutic effects. 24:53 So, G&RH is normally secreted in a pulsatile fashion by the hypothalamus 24:59 and travels to the anterior pituitary where it binds to G&R receptors and 25:05 stimulates the release of luteinizing hormone LH and follical stimulating hormone FSH. These ginatotropins signal 25:13 the ovaries or the testes to produce sex hormones, estrogen, progesterone in 25:18 women, testosterone in men. Uh, luoprololi lupron as a GNR agonist 25:26 initially mimics the action of natural G&R causing an acute flare response with 25:33 uh increased LHFSH secretion which temporarily increases sex hormone 25:38 production. However, the continuous administration which is in the depo 25:44 formulations, the GNR receptors in the pituitary become desensitized and 25:50 downregulated. And after about 2 to four weeks of continuous exposure, LH and FSH 25:56 secretion is profoundly suppressed, leading to what’s termed as chemical 26:01 castration. Testosterone levels in men drop to castrated levels less than 50 26:08 and estrogen production is marketkedly suppressed in women. This bifphasic 26:13 response creates both therapeutic applications and management challenges in prostate cancer where tumor growth is 26:20 typically androgen dependent and the ultimate goal is testosterone suppression. However, the initial 26:27 testosterone surge during the flare phase can temporarily worsen symptoms potentially causing increased bone pain, 26:34 urinary obstruction, or even spinal cord compression in patients with metastatic 26:40 disease. This is why uh luoprolide is often started with an anti-ad androgen 26:47 like bicladamide for the first two to four weeks to block the effects of the 26:52 testosterone surge. The FDA has approved lupalide for multiple indications across 26:59 formulations. In oncology, it’s used for palletive treatment of advanced prostate cancers. In gynecology, various 27:06 formulations are approved for endometriosis, for pain management and lesion reduction and for fibroids. 27:13 Typically for pre-operative uh hematological improvement in anemic patients. In pediatrics, it’s used for 27:20 central precocious p puberty basically to halt the premature sexual development of these young people. Now, there are 27:28 adex uh adverse effect profile that reflects profound hormonal suppression. 27:34 In men treated for prostate cancer, hot flashes affect about 59% of the patients. Other common effects include 27:41 general pain, swelling, bone pain. Um long-term use of these medications leads 27:47 to metabolic changes. It increases fat mass. It decreases lean mass. It worsens 27:53 insulin sensitivity, disrupts the cholesterol uh lipid panels, increases 27:59 diabetic risk, has some concerns over cardiovascular disease. And the metaanalysis have shown increased risks 28:06 of heart infarction, myocardial inffection, sudden cardiac death, and stroke in populations receiving 28:13 long-term androgen deprivation therapy. The bone effects are particularly dramatic. Without sex hormones, bone 28:20 density decreases significantly, typically 3 to 4% per year during the 28:26 first two to three years of therapy. And this bone loss may not fully be reversible after the the therapy 28:32 discontinues. The American Society of Clinical Oncology recommends bone density monitoring and consideration of 28:39 bisphosphinates uh in men receiving long-term androgen deprivation. In women treated for 28:46 endometriosis or fibroids, the estrogen suppression creates a hypoestrogenetic state similar 28:54 to menopause. Hot flashes affect 90% of patients with other common effects 29:00 including headaches, emotional irritability, decreased sex drive, vaginal dryness, bone density loss. And 29:08 because of these bone concerns and treatment duration with endometriosis, typically limited to six months, though 29:14 some formulations allow for longer use with adback hormonal therapy to 29:20 partially mitigate these side effects. The mood and cognitive effects can be s 29:25 significant. I’ve seen it over the years. the depression, the memory impairment, difficulty focusing and 29:31 concentrating. It can be very very traumatic and the quality of life that 29:37 happens for these uh women and men can be unbearing for many of them. Um, from 29:44 an integrative perspective, patients receiving this medication need comprehensive support care. Bone health 29:51 interventions using calcium, vitamin D, vitamin K2, weightbearing exercise, 29:58 cardiovascular risk management becomes critical, including blood pressure monitoring, lipid management, diabetes 30:05 screening. For hot flashes management, some patients respond to black coohos, 30:10 sage, or vitamin E. Though evidence is mixed and individual response varies, 30:16 omega-3s may help with the mood and the inflammation, resistance training becomes specifically important to 30:22 preserve lean muscle mass in the face of hormonal suppression. 30:27 Now there’s something called calcetonin salamon which is marketed as miaelin. 30:34 It is a nasal spray. It is now discontinued. And foral is the new 30:39 synthetic polyeptide hormone of 32 amino acids identical to calcetonin of salamon 30:47 origin. It represents an interesting case study in how initial promise gives 30:52 way to safety concerns that regulate a therapy to historical footnote status. 30:58 Calcetonin is naturally occurring hormone in humans. It’s secreted by the paraphalicular sea cells in the thyroid 31:04 gland. Its primary physiological role is to lower blood calcium levels by 31:10 directly inhibiting osteoclast activity, reducing bone reabsorption, increasing 31:16 renal calcium secretion or excretion, and possibly reducing the intestinal 31:21 calcium absorption. So, salamon calcetonin is used therapeutically because it’s more potent and longer 31:27 acting than human calcetonin. The FDA initially approved calceton and salmon 31:34 for several indications post-menopausal osteoporosis in women more than five 31:39 years post-menopausal when alternative treatments are not sustainable. Padet’s 31:44 disease for bone and hypercalcemium as emergency treatments. The nasal spray formulation is particularly popular for 31:53 osteoporosis because it offered a non-injectable alternative to bisphosphinates. 31:58 However, in 2012, the European Medicine’s Agency, EMA, conducted a 32:05 comprehensive safety safety review after a poolled analysis of 21 clinical trials 32:10 involving over 10,000 patients showed a statistically significant increase in 32:15 malignancy risk in patients treated with calceton salamon compared to compared to 32:21 placebo. The overall malignancy rate was 4.1% in calcetonin treated patients 32:28 versus 2.9% in placebo patients. The types of cancer 32:34 varied with no single cancer type predominating, making it difficult to establish a clear mechanistic link. 32:41 However, the signal was concerning enough that the EMA restricted the use of calcetonin containing medicines. In 32:48 the United States, the FDA issued communications about malignancy signal and conducted its own review. While they 32:56 didn’t fully withdraw the drug, the cons consensus shifted dramatically. The nasal spray formulations miaelson was 33:03 voluntarily discontinued by the manufacturer and current clinical practice guidelines now consider 33:10 calcetonin salamon as a second line or lower option for osteoporosis. While 33:15 behind bisphosphinates, dennism mob, uh, terrapeptide, the analesic effect of 33:21 calcetonin in bone pain, particularly in acute vitibbral, uh, compression 33:26 fractions from osteoporosis or pageantss disease may still provide a role for short-term use in these selected 33:32 patients. The mechanism of this pain relief is unclear, but may involve 33:38 effects of endorphin systems and/or direct actions on pathways. The history serves as an important reminder in 33:45 peptide medicine. Initial approval and early clinical use does not guarantee 33:50 long-term safety effects. Post marketing surveillance and poolled analysis of the clinical trial data can reveal adverse 33:58 effects that weren’t apparent in initial studies. It also underscores why newer 34:04 agents with better safety profiles um have largely replaced calcetonin in 34:10 clinical practice. So this is really an important thing. Not one thing stays the same forever. We have to change as we 34:18 identify new and better products as we identify problems and concerns. I will 34:24 always tell my patients if you are uncertain of taking a new drug which we 34:30 all should be wait five years. Within five years we are going to find the 34:36 problems that they didn’t find in the clinical studies. Remember, a lot of these clinical studies are small, small 34:43 groups, short periods of time. It’s expensive to do these trials. So, if you 34:49 wait for five years, in the first two to three years, you will see the problem start to emerge. And what are you going 34:55 to look for? You’re going to look for the the news um commercials from lawyers 35:02 suing a drug. And they will tell you what the problem is. and then you can decide, is this something that I want to 35:09 use or not. Don’t jump on bandwagon and be the first one to do this, especially 35:14 if you’re sensitive. You know, give it time so you can see exactly what’s going on. So, I’m going to end our show on 35:22 this and we are going to pick up on part three of peptide therapy in our next 35:28 segment where we’re going to talk about the investigational peptides and some 35:34 exciting things that are happening with that. So, I want to thank you for joining me today on Let’s Talk Wellness 35:39 Now. It’s always a pleasure having a conversation with you guys and I hope this brings value to you with what we’re 35:45 talking about. If you have ideas for topics that you want me to discuss, 35:51 please message us, you can share your comments on Facebook, you can email us, 35:58 um you can get a hold of us however you would like to share that. I do look at the comments below in the episodes as 36:04 well. So you can place your comments there. And once again, one of the best things you can do for me is like, 36:11 subscribe, and share so that we can spread the messages of what we’re doing. 36:16 I do this at no cost. I don’t make any money out of this. I do this as an 36:21 educational purpose for everybody else. I love doing it, but it really helps us 36:28 on the algorithms if you would be just willing to like, subscribe, and share. 36:33 So, thank you for spending your time with me. I know time is important.The post Episode 257 – Peptides for Sexual Wellness & Hormonal Health: PT-141, Growth Hormones, Bone Health & More! first appeared on Let's Talk Wellness Now.

Im Traum fliegen Gabriele und der Papierdrache durch die Nacht in die gelbe Zeit. Denn der Gelbe Hase möchte sie kennenlernen. Hier oben ist alles ganz anders und luftig leicht. Aus der OHRENBÄR-Hörgeschichte: Gabriele in der gelben Zeit (Folge 4 von 7) von Fritz Mikesch. Es liest: Peter Simonischek. ▶ Mehr komplette Hörgeschichten gibt es hier: https://www.ohrenbaer.de/podcast/komplette-hoergeschichten.html ▶ Mehr Hörgeschichten empfohlen ab 6: https://www.ohrenbaer.de/podcast/empfohlen-ab-6.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

Stoizismus klingt nach alter Philosophie, aber so verrückt es klingt: Diese 2000 Jahre alten Gedanken haben das Zeug, dein nächstes Abenteuer da draußen zu verändern und dir am Ende vielleicht sogar eine neue Haltung zu schenken – eine, die dir nicht nur outdoor, sondern auch auf anderen Ebenen des Lebens hilft. In dieser Folge stelle ich dir den Stoizismus vor, seine Ursprünge im antiken Griechenland, die zentralen Ideen von Kontrolle, Akzeptanz und innerer Haltung, und ich zeige dir, warum diese Philosophie heute aktueller ist denn je. Was bedeutet die „Dichotomie der Kontrolle“ konkret, wenn das Wetter umschlägt? Wie hilft dir Amor Fati dabei, Rückschläge anders zu betrachten? Was hat Memento Mori damit zu tun? Und warum ist die Natur vielleicht das beste Trainingscamp für Gelassenheit, Resilienz und mentale Stärke? Diese Folge verbindet Philosophie mit Outdoor-Erfahrungen, Mindset mit Naturverbundenheit und alte Weisheit mit modernen Herausforderungen. Für mehr Klarheit im Kopf, mehr Ruhe im Sturm und mehr innerer Freiheit. Ach ja, und dann gibt's noch News zu Big-Wave-Surfer Sebastian Steudtner und einem neuen Fernwanderweg durch Europa ... // Die Infos zum Gewinnspiel für die Teilnahme am Mikroabenteuer-Wochenende für Familien mit HABA und Christo Foerster in der Rhön findest du hier: https://www.haba-play.com/de-de/s/service-vorteile/gewinnspiel // Alle Werbepartner des FREI RAUS Podcast und aktuelle Rabatte für Hörer:innen findest du unter https://www.christofoerster.com/freiraus-partner // Hier kannst du den wöchentlichen Newsletter zum Podcast abonnieren: https://www.christofoerster.com/freiraus // Ich freue mich, wenn du den Podcast mit einem keinen Beitrag unterstützt! Alle Infos dazu ebenfalls auf https://www.christofoerster.com/freiraus // Outro-Song: Dull Hues by Lull (audiio.com)

Iniciamos una serie de tres episodios para quienes desean entender a profundidad el verdadero rol estratégico de Recursos Humanos.En esta primera sesión hablamos de un tema clave:¿Cómo debe el área de RH acompañar al CEO y a la alta dirección?Nuestra host, la Dra. Ana María, conversa con Juan Antonio Escobedo, ejecutivo con más de 28 años de experiencia en empresas globales, quien comparte su visión sobre el papel que juega Recursos Humanos cuando trabaja de cerca con el Director General.En este episodio abordamos:​ Qué debe entender RH del negocio antes de acercarse al CEO​ Cómo construir credibilidad en la mesa de decisiones​ La diferencia entre operar procesos y aportar visión estratégica​ Qué espera realmente un CEO de su cabeza de Recursos HumanosSi trabajas en RH o aspiras a un rol de liderazgo en el área, esta serie te dará claridad sobre cómo evolucionar de ejecutor a socio estratégico.Este es el episodio 1 de 3.

Was für eine traumhafte Nacht! Erst hat Gabriele den Drachen losgelassen, damit er frei ist. Nun fliegt sie mit ihm zum Vollmond hinauf, denn sie wollen in die Zeit des Gelben Hasen. Aus der OHRENBÄR-Hörgeschichte: Gabriele in der gelben Zeit (Folge 3 von 7) von Fritz Mikesch. Es liest: Peter Simonischek. ▶ Mehr komplette Hörgeschichten gibt es hier: https://www.ohrenbaer.de/podcast/komplette-hoergeschichten.html ▶ Mehr Hörgeschichten empfohlen ab 6: https://www.ohrenbaer.de/podcast/empfohlen-ab-6.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

Abends schaut der Vollmond durchs Fenster ins Kinderzimmer. Gabriele denkt an den Papierdrachen, den ihr Großvater repariert. Da taucht der Drache auf und sie schwebt hinaus. Aus der OHRENBÄR-Hörgeschichte: Gabriele in der gelben Zeit (Folge 2 von 7) von Fritz Mikesch. Es liest: Peter Simonischek. ▶ Mehr komplette Hörgeschichten gibt es hier: https://www.ohrenbaer.de/podcast/komplette-hoergeschichten.html ▶ Mehr Hörgeschichten empfohlen ab 6: https://www.ohrenbaer.de/podcast/empfohlen-ab-6.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

Gabriele lässt mit ihrem Großvater Julius den Drachen steigen, den er ihr aus Papier gebaut hat. Der verheddert sich in einem Baum. Danach hat er ein Loch. Und Gabriele lässt ihn los. Aus der OHRENBÄR-Hörgeschichte: Gabriele in der gelben Zeit (Folge 1 von 7) von Fritz Mikesch. Es liest: Peter Simonischek. ▶ Mehr komplette Hörgeschichten gibt es hier: https://www.ohrenbaer.de/podcast/komplette-hoergeschichten.html ▶ Mehr Hörgeschichten empfohlen ab 6: https://www.ohrenbaer.de/podcast/empfohlen-ab-6.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

Gabriele lässt den Papierdrachen los, damit er hinfliegen kann, wohin er will. Wer würde es für möglich halten, dass der leere Becher des chinesischen Dichters ein Schmetterling wird? Oder dass der Schmetterling den Drachen in einen Namen verwandelt, der lebendig wird? Im Traum ist alles möglich. Und so besucht Gabriele nachts den Gelben Hasen in der gelben Zeit. Alle 7 Folgen der OHRENBÄR-Hörgeschichte: Gabriele in der gelben Zeit von Fritz Mikesch. Es liest: Peter Simonischek. ▶ Mehr komplette Hörgeschichten gibt es hier: https://www.ohrenbaer.de/podcast/komplette-hoergeschichten.html ▶ Mehr Hörgeschichten empfohlen ab 6: https://www.ohrenbaer.de/podcast/empfohlen-ab-6.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

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C dans l'air du 27 février 2026 - "Epstein ou Epstine" : à quoi joue Mélenchon ?Sa prise de parole était attendue. Le leader insoumis Jean-Luc Mélenchon a tenu hier un meeting à Lyon, deux semaines jours après la mort du militant nationaliste Quentin Deranque, après des affrontements avec des antifascistes. Devant 2 000 sympathisants galvanisés, l'ancien député des Bouches-du-Rhône a condamné les événements tout en accusant le groupuscule identitaire Nemesis d'avoir orchestré l'affrontement : « Elles voulaient un incident pour que surgissent des gens armés, casqués, cagoulés. (…) Une organisation criminelle ! ». Tout en condamnant la violence de « ces jeunes qui ont perdu leur sang-froid », il a demandé la dissolution du collectif Nemesis et renouvelé son soutien à La Jeune Garde, groupe déjà dissous en juin 2025 : « La Jeune Garde n'a jamais voulu à aucun moment la mort de qui que ce soit, parce que leur formation ne prévoit pas qu'on tue ». Commentant enfin le scandale Epstein, il a ironisé sur la prononciation de ce nom. Une charge antisémite ciblant les médias, accusés à demi-mots de vouloir couvrir un scandale international, dans une approche très complotiste. Ses propos ont fait réagir sur X le président du Conseil représentatif des institutions juives de France, Yonathan Arfi : « N'en déplaise à Jean-Luc Mélenchon, un élève de cinquième sait qu'en anglais “Epstein” se prononce “Epstine” (…) Voir dans cette prononciation une manipulation est un délire complotiste aux vrais relents antisémites ». Sur le côté droit de l'échiquier politique, ce sont deux anciens de la famille LR qui se livrent un duel fratricide à Nice. D'un côté, le maire actuel, Christian Estrosi, candidat Horizons qui vise un quatrième mandat, et de l'autre le député Union des droites (UDR) Eric Ciotti, allié du RN. Les deux candidats se sont mutuellement disputé des collaborateurs, à l'image de Françoise Meunier, adjointe historique de Christian Estrosi, récemment passée dans le camp Ciotti. « On ressent des coups bas comme je n'en avais que rarement ressenti dans ma vie politique », a récemment déclaré Christian Estrosi à RTL. Porté par la vague RN à Nice, ville très ancrée à droite, Eric Ciotti est largement en tête dans les derniers sondages, tandis que Christian Estrosi semble payer sa proximité avec Emmanuel Macron. Le président de la République, lui, n'a pas hésité à profiter du remaniement d'hier soir pour placer plusieurs de ses proches à des postes clés, une semaine après la nomination polémique de sa ministre des Comptes publics Amélie Montchalin à… la Cour des comptes, chargée de certifier les comptes de l'État. Catherine Pégard, 71 ans, ancienne présidente du château de Versailles, jusqu'alors conseillère culture à l'Élysée, succède à Rachida Dati au ministère de la Culture. Proche du couple présidentiel, l'ex-ministre de la ville Sabrina Roubache est nommée ministre déléguée à l'enseignement, à la formation professionnelle et à l'apprentissage. Quant à Maud Bregeon, elle récupère le portefeuille de l'énergie, en plus de rester porte-parole du gouvernement. Comment interprété le dérapage de Jean-Luc Mélenchon, perçu comme antisémite et complotiste ? Une telle stratégie de radicalisation ne le condamne-t-il pas à la marginalisation ? Jusqu'où ira la guerre fratricide entre Christian Estrosi et Eric Ciotti pour la mairie de Nice ? Et comment interpréter le remaniement gouvernemental d'hier soir ?Experts :- Corinne LHAIK - Journaliste – L'Opinion - Anne-Charlène BEZZINA - Constitutionnaliste et politologue, maître de conférences en droit public - Université de Rouen et Sciences Po - Aurore MALVAL - Grand reporter au service politique – Marianne - Jérôme FOURQUET - Institut de sondages IFOP, auteur de « Métamorphoses françaises »

Auf dem Rückweg wird Kasper lustig. Was haben sie nicht alles erlebt! Das führt er alles auf. Schade, dass Kasimir nicht mit auf die Bühne kann. Aber: daneben gibt es viel zu tun! Aus der OHRENBÄR-Hörgeschichte: Kasper und Kasimir auf der Suche nach einer neuen Geschichte (Folge 7 von 7) von Peter Nink. Es liest: Otto Mellies. ▶ Mehr komplette Hörgeschichten gibt es hier: https://www.ohrenbaer.de/podcast/komplette-hoergeschichten.html ▶ Mehr Hörgeschichten empfohlen ab 4: https://www.ohrenbaer.de/podcast/empfohlen-ab-4.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

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Der Theaterbesuch bei Korbinian Korb hat Kasper und Kasimir gut gefallen. Finden die tollsten Abenteuer wirklich auf der Bühne statt? Da sehen sie einen Dieb auf dem Marktplatz. Aus der OHRENBÄR-Hörgeschichte: Kasper und Kasimir auf der Suche nach einer neuen Geschichte (Folge 6 von 7) von Peter Nink. Es liest: Otto Mellies. ▶ Mehr komplette Hörgeschichten gibt es hier: https://www.ohrenbaer.de/podcast/komplette-hoergeschichten.html ▶ Mehr Hörgeschichten empfohlen ab 4: https://www.ohrenbaer.de/podcast/empfohlen-ab-4.html ▶ Mehr Infos unter https://www.ohrenbaer.de & ohrenbaer@rbb-online.de

The VITURE Beast is proving itself to be one of the best of the bunch for XR glasses right now. You get a huge 174" ultra-sharp micro-OLED display, excellent immersive audio, 3DoF anchoring, very useful built-in screen controls, along with 3D mode. The screen anchoring really has been the game changer though. ✨Featured items:

Seb Pradal is a wine Renaissance man—a vin-aissance man, you could say. An acclaimed French sommelier and owner of the Parisian restaurant La Petite Régalade, Pradal also co-owns a wine-importing company that operates in Mexico and Colombia while simultaneously working as a viticultural consultant on estates in Burgundy, Bordeaux, and the Rhône Valley. As if that weren't enough to keep his iCal full, he's also the head wine consultant on the Apple TV series Drops of God. Pradal works closely with the show's writers and actors to ensure that every wine-related scene is accurate and authentic. In this episode, Pradal tells us about how he brought his deep wine industry knowledge to the series, his thoughts on the broader challenges facing the industry, and how working on the show has changed his life. Is there a guest you want us to interview? A topic you want us to cover? We want to hear from you! Email us at podcast@wineenthusiast.com. Remember to rate and review us on Apple Podcasts, Spotify, or wherever you listen to podcasts. Go to WineEnthusiast.com for the latest beverage industry coverage and all the tools you need to bring your love of wine to life. And wait, there's more! Get over 70% OFF the original cover price by subscribing to Wine Enthusiast magazine today!    FOLLOW US: TikTok: @wineenthusiast Instagram: @wineenthusiast Facebook: @WineEnthusiast

Tu souhaites faire former tes managers ? Prends contact avec adelie@outilsdumanager.com pour voir si l'École des Managers est faite pour eux.***Découvre ce que nous avons créé pour t'aider à aller plus loin :Des formactions pratiques et concrètes pour manager efficacement, quel que soit ton rôle ou ton secteur.Une communauté unique en ligne, le CIEL, où dirigeants et cadres dirigeants, s'entraident pour réussir ensemble.L'offre exclusive du moment pour t'aider à passer à l'action dès aujourd'hui.Clique ici pour explorer le catalogue ODM : https://www.formactions.outilsdumanager.com/cataloguecomplet***Dans ce deuxième épisode de notre série, Cédric s'attaque aux deux grands modèles qui piègent les entreprises : le management à la pression et le management à la bienveillance pure.Beaucoup de dirigeants oscillent entre ces deux extrêmes sans jamais trouver l'équilibre. Entre la logique darwinienne de Jack Welch (General Electric) qui consiste à licencier les 10 % les moins performants et le mirage de la bienveillance inconditionnelle qui dérive souvent vers le laisser-faire , Cédric vous explique pourquoi aucune de ces voies ne garantit une performance durable.Au programme :Le management à la pression : Pourquoi le pouvoir hiérarchique seul crée des "collaborateurs zombies" et des comportements passifs-agressifs.Le piège de la bienveillance : Pourquoi être "trop gentil" sans exigence détruit le respect et la productivité.Le rôle du chef : Pourquoi vos collaborateurs attendent que vous sachiez dire "non" et que vous fassiez le tri dans les initiatives.Vers la Troisième Voie : Une introduction à la méthode qui réconcilie respect et performance.Hébergé par Ausha. Visitez ausha.co/politique-de-confidentialite pour plus d'informations.

In this live episode recorded at the AHR Expo 2026 Podcast Pavilion in Las Vegas, host Bryan sits down with longtime friend and industry expert Nikki Krueger of Santa Fe and AprilAire. Nikki brings over 15 years of experience in indoor air quality and whole-home dehumidification to the conversation, having started her career with AprilAire before moving to Santa Fe (formerly Ultra Aire) — and now coming full circle as the two brands have integrated under the AprilAire umbrella as of January 1st of this year. The episode dives deep into a topic close to both hosts' hearts: how to properly manage indoor humidity, and what role a whole-home ventilating dehumidifier plays in a comprehensive HVAC system strategy. Bryan and Nikki lay out a holistic framework for tackling moisture problems, emphasizing that a dehumidifier should be the last tool added — not the first. Before reaching for dedicated dehumidification equipment, contractors need to assess the building envelope for air leaks, evaluate whether the air conditioning system is properly sized (oversizing is a major contributor to poor latent removal), confirm that the AC is set up with the right airflow and sensible heat ratio, and take into account the ventilation strategy and occupant behavior. The pair discuss real-world scenarios ranging from elderly residents in Florida who keep their thermostats at 80°F, to a project in Barbados where overcooling caused interstitial condensation in walls and ceilings. The message is clear: humidity control is a systems problem, not a single-product fix. A significant portion of the episode is dedicated to proper installation practices for whole-home dehumidifiers. Nikki explains why Santa Fe recommends pulling from a dedicated return and discharging into the supply side of the AC duct — rather than tying into the return side — because the heat generated by dehumidification (roughly 1,054 BTUs per pint of water removed) can warm the AC evaporator coil and reduce its latent removal capacity. Bryan adds nuance around dew point management when routing outdoor air ducts, and both hosts agree that fan operation strategy (continuous low-speed vs. intermittent) matters more in tight, low-load homes where mixing is harder to achieve naturally. They also clarify a common misconception: a ventilating dehumidifier is not a dedicated outdoor air system (DOAS) and does not automatically condition incoming ventilation air before it enters the home. The conversation wraps up with an exciting look at Santa Fe's newly launched Ultra V Series, which features an upgraded 8-inch ventilation duct (up from 6 inches), a more powerful fan for handling higher static pressure in retrofit applications, a new digital control panel, and a wired remote humidity sensor that can be placed in the living space for more accurate readings. Nikki and Bryan also field audience questions on topics like short-cycling risks from oversized dehumidifiers and why Santa Fe chose a wired sensor over wireless (accuracy, reliability, and fewer callback headaches). Bryan closes by noting that rising dew points across most U.S. markets over the last 20 years make whole-home dehumidification more relevant than ever — and that any region where you can see green grass outside is a candidate for a more advanced moisture control strategy. Topics Covered Introduction to Nikki Krueger and the merger of Santa Fe and AprilAire under one brand The purpose of whole-home ventilating dehumidifiers and how they fit into an overall HVAC system strategy Latent vs. sensible heat loads explained — and why both matter for comfort and moisture control Geographic reach of humidity problems — why dehumidification isn't just a Florida or Gulf Coast issue Ken Gehring ("Teddy Bear"), inventor of the whole-house ventilating dehumidifier, and his framework for diagnosing moisture problems The four-factor checklist before deploying a dehumidifier: building envelope, AC sizing, AC setup/airflow, and ventilation strategy How occupant behavior (thermostat preferences, activity levels, large households) creates latent load variability The dangers of overcooling — how setting thermostat too low can cause interstitial condensation in walls, ceilings, and attics Sensible heat ratio (SHR) and its role in a system's ability to remove moisture — targeting ~350 CFM per ton in humid climates Why dehumidifiers should connect to a dedicated return and discharge into the supply — not tie into the AC return side How dehumidifier heat output (~1,054 BTUs per pint) can reduce AC coil efficiency when ducted incorrectly Fan-on strategy debate: when running continuous low-speed circulation helps vs. hurts humidity control Tighter homes, smaller systems, and the importance of air mixing strategies (including ceiling fans)  Ventilating dehumidifiers vs. dedicated outdoor air systems (DOAS) — clearing up a common misconception about how ventilation air is conditioned Dew point management for outdoor air ducts — preventing condensation inside duct runs Using dehumidifiers to address sweating ductwork in multi-story homes Rising dew points over the past 20 years and what "green grass climates" means for dehumidification demand Heat pump oversizing challenges in colder climates and the downstream impact on AC latent removal Santa Fe's new Ultra V Series: 8-inch ventilation duct, stronger fan, digital controls, and wired remote humidity sensor Why proper dehumidifier sizing matters: short-cycling risks, moisture reservoir release, and uneven RH throughout the home Why Santa Fe chose a wired humidity sensor — accuracy, reliability, and reducing contractor callbacks Audience Q&A: oversizing consequences, short-cycling mechanics, and sensor placement best practices   Learn more about Santa Fe Dehumidifiers at santafeproducts.com.  Connect with Nikki Krueger on LinkedIn or Instagram @nikkikruegerIAQ. Check out the work of Ken Gehring ("Teddy Bear") or ask him a question on the HVAC Talk Forum: hvac-talk.com. Have a question that you want us to answer on the podcast? Submit your questions at https://www.speakpipe.com/hvacschool. Purchase your tickets or learn more about the 7th Annual HVACR Training Symposium at https://hvacrschool.com/symposium. Subscribe to our podcast on your iPhone or Android. Subscribe to our YouTube channel. Check out our handy calculators here or on the HVAC School Mobile App for Apple and Android.