Podcasts about viagra

Our West Coast reporting continues with LA Legend Ali Macofsky as we get into SATC S2E8, “The Man, the Myth, the Viagra.”  Samantha test-drives sex with an old coot, Carrie proves the haters right and ditches Miranda for Veal Night at Big's, Steve is introduced in such a hot way, and Charlotte is sort of just there.  We catch up with Ali about how LA is sexless and the epicenter of looksmaxxing, reminisce over Evan's first kiss (on the Amtrak!) and realize how working at a dry bar is the natural next step for a babysitter.  After surviving the Trump jump-scare and note how he subscribes to the pop star theory of never repeating hairstyles, we discuss how Frank Sinatra is Big's Sabrina Carpenter, laud Miranda's lotion acting, and decide on our age ranges for lovers.  Find out where Ali is performing next at alimacofsky.com or @notalimac Get 25% Off Cowboy Colostrum with code GIRLSREWATCH at http://cowboycolostrum.com/GIRLSREWATCH. Use code GIRLSREWATCH at jonesroadbeauty.com to get a Free Gift with your first purchase! #JonesRoadBeauty #ad Our listeners can buy one pair of glasses and get 20% off any additional pairs at WarbyParker.com/GIRLSREWATCH — and using our link helps support the show. #WarbyParker #ad Learn more about your ad choices. Visit megaphone.fm/adchoices

What do dinosaur fossils, Bubble Wrap, Super Soakers, Viagra, and Bob Ross have in common? More than you'd think. In this episode of The Box of Oddities, Jethro introduces the astonishing true story of Baron Franz Nopcsa—the eccentric Hungarian aristocrat who transformed himself into one of history's most visionary paleontologists. Decades before mainstream science caught up, he proposed that some dinosaurs were warm-blooded, cared for their young, and evolved through island dwarfism. But his remarkable life didn't stop there. Nopcsa also became an explorer, linguist, spy, and even launched a serious bid to become King of Albania. His extraordinary achievements, however, are overshadowed by one of the most tragic endings imaginable. Then Kat lightens the mood with a celebration of history's greatest happy accidents. Discover how forgotten experiments and unexpected mistakes gave us saccharin, Bubble Wrap, the Super Soaker, and even Viagra—proving that some of humanity's biggest breakthroughs happened because someone was curious enough to ask, "What else could this be?" It's an episode filled with brilliant minds, bizarre history, accidental inventions, dark twists, and the wonderfully unexpected. In this episode: * Baron Franz Nopcsa and the dinosaurs that changed science * The scientist who wanted to become King of Albania * Paleontology, espionage, and eccentric genius * The tragic final chapter of Franz Nopcsa's life * The accidental invention of saccharin * How Bubble Wrap went from failed wallpaper to shipping legend * The surprising origin of the Super Soaker * Why Viagra was originally developed for heart disease * Bob Ross, happy accidents, and the value of unexpected discoveries If you love strange history, forgotten inventors, scientific oddities, accidental discoveries, and true stories that are stranger than fiction, this episode belongs in your queue. Learn more about your ad choices. Visit megaphone.fm/adchoices

Mr. Jones from the We Got A Thing podcast called in to talk all about having prostate cancer, losing his erections and then swinging again years later. Tune in to hear how he found out he had prostate cancer despite having zero symptoms, why routine bloodwork and PSA testing probably saved his life, what his MRI, biopsy and Gleason score revealed, why he decided on surgery vs. radiation, what recovery was really like, how long he had to wear a catheter, when he regained bladder control, how and why he lost penis length after surgery, why he could no longer ejaculate, how prostate removal affected his erections and orgasms, why Viagra and Cialis didn't work for him, how Bimix helped him get his sex life back, what it was like returning to the swinging lifestyle after prostate cancer, why communication with his female partners became more important than ever, what every guy should know about PSA testing and prostate cancer screening, plus a whole lot more. To get in touch with him and join his mens only community you can email him at  mr.jones@wegottathing.com ir find them here: https://wegottathing.com GET A COPY OF THE STRICTLY ANONYMOUS BOOK! Strictly Anonymous Confessions: Secret Sex Lives of Total Strangers. A bunch of short, super sexy, TRUE stories. GET YOUR COPY HERE: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://amzn.to/4i7hBCd⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  or Pre-order audiobook version ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠here⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠   To see HOT pics of my female guests + hear anonymous confessions + get all the episodes early and AD FREE, join my Patreon! It's only $7 a month and you can cancel at any time. You can sign up here: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.patreon.com/StrictlyAnonymousPodcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ and when you join, I'll throw in a complimentary link to my private Discord! To join SDC and get a FREE Trial! click here: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.sdc.com/?ref=37712⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ or go to SDC.com and use my code 37712 Want to be on the show? Email me at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠strictlyanonymouspodcast@gmail.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ or go to ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://www.strictlyanonymouspodcast.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ and click on "Be on the Show." Want to confess while remaining anonymous? Call the CONFESSIONS hotline at 347-420-3579. All voices are changed.   Sponsors:  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://beduc.at/pd2626-anonymous⁠⁠⁠⁠ Click here to take the quiz and  get your personalized SUMMER roadmap to sexual happiness ⁠⁠⁠⁠⁠⁠⁠⁠ ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://Rythm.Health/STRICTLYANON⁠⁠⁠⁠⁠⁠ ⁠⁠for 15% OFF your first month  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://VB.Health⁠⁠⁠⁠⁠⁠⁠ - To get 10% off DRIVE BOOST by VB Health, use code: STRICTLY   ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://bluechew.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ — Buy 2 months of Bluechew GOLD and get the third month FREE! Use code: STRICTLYANON⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  Follow me! Instagram  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/strictanonymous/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ X  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/strictanonymous?lang=en⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Website  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠http://www.strictlyanonymouspodcast.com/⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Everything else: ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://linktr.ee/Strictlyanonymouspodcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

What if there was a pill that could radically change how women feel desire? In this episode, DB talks to her mom, the incredible Dr. Rebecca Levy-Gantt, about libido pills. What can they do -- and what's more marketing than reality? Are pills like Addyi the "Viagra for women"? FROM THIS EPISODE: "Testosterone, Pleasure, and the Libido Myth with Dr. Rebecca Levy-Gantt" from Season 13; "Hyposexuality Disorder with Dr. Rebecca Levy-Gantt" from Season 4; Listen to the Sex and Psychology Podcast here to go to an episode we love on your podcast app of choice! ABOUT OUR GUEST: Rebecca Levy-Gantt is a retired OB-GYN, nationally certified menopause practitioner, and author with more than 30 years of experience caring for women through every stage of reproductive and menopausal health. After decades in clinical practice, she now focuses on writing, speaking, and educating about menopause, aging, women's health, and the emotional realities of life in medicine. She is the author of the memoir Womb With A View and writes widely on women's health, relationships, and life transitions with warmth, honesty, and humor. TAKE OUR SMUT QUIZ: Find your page-turning turn-on with our new SMUT QUIZ! In just 5 questions, you'll get right to the good stuff with curated pages, poems, and audios. No slow burn. No fluff. Just pleasure.; Take the quiz here: https://sexedwithdb.fillout.com/smutquiz  ASK AN ANONYMOUS SEX ED QUESTION: Fill out our anonymous form to ask your sex ed question. ABOUT SEX ED WITH DB: Sex Ed with DB is your go-to podcast for smart, science-backed sex education — delivering trusted insights from top experts on sex, sexuality, and pleasure. Empowering, inclusive, and grounded in real science, it's the sex ed you've always wanted. Season 14 of Sex Ed with DB is ALL ABOUT PLEASURE! Solo pleasure. Partnered pleasure. Orgasms. Porn. Queer joy. Kinks, sex toys, fantasies -- you name it. We're here to help you feel more informed, more empowered, and a whole lot more turned on to help YOU have the best sex. GET IN TOUCH: Email: sexedwithdb@gmail.com CONNECT WITH US: Instagram: @sexedwithdbpodcast; TikTok: @sexedwithdb; Threads: @sexedwithdbpodcast; YouTube: Sex Ed with DB; X: @sexedwithdb SEX ED WITH DB SEASON 14 SPONSORS: Uberlube, Magic Wand, Nancy, and Happy V. Get discounts on all of DB's favorite things here! DISCOVER SEX POSITIVE EVENTS IN YOUR CITY: Subscribe to our newsletter for S.E.X I.R.L: your curated monthly list of sex-positive events, spaces, and experiences happening in person across major cities. FOR SEXUAL HEALTH PROFESSIONALS: Check out DB's workshop: "Building A Profitable Online Sexual Health Brand" SEASON 14 TEAM: Creator, Host & Executive Producer: Danielle Bezalel (DB) (she/her); Producer and Growth Marketing Manager: Wil Williams (they/them); Social Media & Communications Manager: Iva Markicevic Daley (she/her) MUSIC: Intro theme music: Hook Sounds; Background music: Bright State by Ketsa; Ad music: Soul Sync by Ketsa, Always Faithful by Ketsa, and Soul Epic by Ketsa.; Thank you Ketsa!

In this episode, Dr. Rachel Rubin explores the connections between sexual health, hormones, and overall well-being. She discusses topics such as the benefits of regular sexual activity, the impact of menopause and birth control on sexual function, and the importance of open communication about intimacy. Listeners will gain insights into practical lifestyle changes, hormonal therapies, and the significance of normalizing conversations around sexual health. Become a Member to Receive Exclusive Content: renamalik.supercast.com Schedule an appointment with me: https://www.renamalikmd.com/appointments ▶️Chapters: 00:00 Health, Fitness, and Hormones 01:38 Vaginal Hormones and GSM 03:53 Lifestyle Changes for Better Sex 04:53 Devices, Erotica, and Permission 09:54 Viagra, Blood Flow, and Women's Arousal 12:43 Better Language for Women's Sexual Health 14:47 Understanding the Vulvar Vestibule 19:56 Birth Control and Hormonal Changes 23:17 Why Better Counseling Matters Stay connected with Dr. Rachel Rubin on social media for daily insights and updates. Don't miss out—follow her now and check out these links! INSTAGRAM - https://www.instagram.com/drrachelrubin/?hl=en FACEBOOK - https://web.facebook.com/DrRachelRubin/?_rdc=1&_rdr# YOUTUBE - https://www.youtube.com/@DrRachelRubin X - https://x.com/drrachelrubin WEBSITE - https://www.rachelrubinmd.com/ Let's Connect!: WEBSITE: http://www.renamalikmd.com YOUTUBE: https://www.youtube.com/@RenaMalikMD INSTAGRAM: http://www.instagram.com/RenaMalikMD TWITTER: http://twitter.com/RenaMalikMD FACEBOOK: https://www.facebook.com/RenaMalikMD/ LINKEDIN: https://www.linkedin.com/in/renadmalik PINTEREST: https://www.pinterest.com/renamalikmd/ TIKTOK: https://www.tiktok.com/RenaMalikMD ------------------------------------------------------ DISCLAIMER: This podcast is purely educational and does not constitute medical advice. The content of this podcast is my personal opinion, and not that of my employer(s). Use of this information is at your own risk. Rena Malik, M.D. will not assume any liability for any direct or indirect losses or damages that may result from the use of information contained in this podcast including but not limited to economic loss, injury, illness or death. Learn more about your ad choices. Visit megaphone.fm/adchoices

Hot and sweaty sex. Viagra. Man hit by the bison in Yellowstone suffered a broken femur. People were betting on Polymarket if Christian Ronaldo would cry at the World Cup. Man spends over $18.5 million betting on Fanduel. MLB player Bryce Harper speaks about the Cameo video he made that was sent to a man with a gambling addiction. Charlie took the RV to Maryland. Hudson Williams seen at Paris Fashion Week burning a photograph of himself because he was mad at autograph seekers. The quarterback for the Jets, Geno Smith, was stopped by cops for the third time in three months. NFL player, Brandon Aiyuk, seen kicking his dog on Instagram. Couple seen disputing on camera during a soccer game. The Hand of God. Witnesses say they saw a man having sex with a vacuum cleaner. People are upset at all the celebrities who went to the Connor McGregor fight. Rapper Boosie is suing two pro-Trump lobbyists over failed pardon attempt for $300k. See omnystudio.com/listener for privacy information.

Hot and sweaty sex. Viagra. Man hit by the bison in Yellowstone suffered a broken femur. People were betting on Polymarket if Christian Ronaldo would cry at the World Cup. Man spends over $18.5 million betting on Fanduel.  See omnystudio.com/listener for privacy information.

Charlie is out. Did JLR bring in his Viagra? How did Skinny react to Krystle revealing his name? An elephant tracked down a man and killed members of his family. See omnystudio.com/listener for privacy information.

Charlie is out. Did JLR bring in his Viagra? How did Skinny react to Krystle revealing his name? An elephant tracked down a man and killed members of his family. Bison attacks a man at Yellowstone National Park. Mitch McConnell. Most searched words in the U.S. Relationship experts say having a 'hall pass' is not healthy. Does Snitzer have a 'celebrity hall pass?' JLR's mom did not want him to date/marry black woman. Woman dropped dead inside supermarket. Rover would still shop even if there was a dead body in the store. NBA announcer was fired after a social media post stated that he was a cheater. Rover went to a World Cup game. Controversy over a play during the game between Norway and England. Rover got a text from bankruptcy box about his AC. People are upset that Lily Collins was shoved at Paris Fashion Week. The smoke detectors are still going off at Rover's house. See omnystudio.com/listener for privacy information.

Sister Christian. How far did B2 walk during the marathon? JLR says he took a Viagra as a test. Charlie took a boner pill on his way home from London.See omnystudio.com/listener for privacy information.

Sister Christian. How far did B2 walk during the marathon? JLR says he took a Viagra as a test. Charlie took a boner pill on his way home from London. Duji unboxes her order of fake flowers. A mother is upset that her son was able to buy illegal fireworks that ended up blowing his hands off. A man cleaning up the beach lost his hand after picking up fireworks remnants. Woman house hunting in Italy claims to have been kidnapped twice in one day in Italy. Krystle reveals Skinny's name. Someone complained about Duji's nail color. Sophie Cunnigham memes. Republican lawmakers are requesting that the WNBA commissioner protect Caitlin Clark from being discriminated against. ABDL. DraftKings. See omnystudio.com/listener for privacy information.

People are outraged by how Subway makes their bread. Charlie has taken Viagra before. A man chopped off his own penis and lit it on fire. Woman training with a flight instructor was in shock when he jumped out of the plane without a parachute. See omnystudio.com/listener for privacy information.

Does Rover feel differently about weighted vests? Would Krystle let someone poop on her for $5k? JLR is trying to get out of paying a bet and describes his shower routine. The World Cup is going to have a halftime show. Bonnie Tyler passed away. Charlie had Sonny's sperm extracted. People are outraged by how Subway makes their bread. Charlie has taken Viagra before. A man chopped off his own penis and lit it on fire. Woman training with a flight instructor was in shock when he jumped out of the plane without a parachute. Cop was shot and killed near where Rover lives. Cuyahoga County paid $400k to settle a discrimination claim. News station comments about their staff's social media accounts.See omnystudio.com/listener for privacy information.

O sonho do Hexa foi adiado novamente, mas mesmo em tempos de tristeza @katiucha e @OdeioPePe estão aqui pra renovar as esperanças do ouvinte, mostrando nesse Vortex 131 que a seleção pode ter sido eliminada, mas a força do caos segue firme e forte. Oferta especial nos planos usando o nosso link no Nordvpn: https://nordvpn.com/vortexpodou CUPOM: VORTEXPODContato comercial: comercial@parasol.company Host: Katiucha Barcelos. Instagram: @katbarcelos | Twitter/X: @katiuchaCo-Host: Pedro Pinheiro. Instagram: @odeiopepe | Twitter/X: @OdeioPePeInstagram: @feedvortexBluesky: @feedvortex.bsky.sociaTwitter: @feedvortexTiktok: @feedvortexReddit: r/feedvortexGrupo paralelo não-oficial do Vortex no telegram: https://t.me/+BHlkG92BfPU5ZjdhEsse grupo é dos ouvintes, para os ouvintes e pelos ouvintes. Não temos qualquer afiliação oficial ou responsabilidade por QUALQUER COISA falada neste grupoLink do post do episódio nas redes sociais:InstagramTwitterLinks comentados no episódio:Mudança de guarda da Hatsune Miku Mexicanos levam fogos e música alta ao hotel da seleção inglesaA equipe da Inglaterra reservou 15 hotéis diferentes, mas os fãs do México ainda descobriram onde eles estavam hospedadosOs hits dos últimos 25 anos de Carnaval, de Xibom BomBom a MacetandoTorcedores mexicanos falham na tentativa de acordar jogadores inglesesHomem se fantasia de 'Olhos Famintos' de madrugada, assusta moradores e é levado para delegacia em Pernambuco "Era brincadeira", diz ‘Lobisomem de Xexéu' após assustar população e parar na delegacia Produção: Thyara Castro, Bruno Azevedo e Aparecido SantosEdição: Joel SukeIlustração da capa: Brann Sousa

A study is claiming that armed civilians often stop active shooters with fewer casualties than police interventions. The authors attribute this advantage to civilians already being on scene and being harder for attackers to identify. The findings are presented as support for concealed-carry rights, though the conclusions remain controversial within broader debates over gun policy and public safety. USA Today reports that rumors about England using Viagra to combat Mexico City's altitude were false. Thomas Tuchel dismissed the claim, while Jordan Henderson joked about it before clarifying he wasn't serious. The underlying issue is real, though: England faced a significant altitude challenge at Estadio Azteca, where the thinner air can affect player performance and endurance. The medical examiner concluded that Helen Massiell Garay Sanchez died from hypothermia after spending the night inside a walk-in freezer at a Miami Dollar Tree store, with alcohol use contributing to her death. Investigators found no evidence of foul play, but her family is pursuing a wrongful-death lawsuit against the retailer seeking $50 million in damages. Reuters reports on a study by researchers from Poland and the Czech Republic that explored why cannibalism became one of humanity's strongest taboos. Their conclusion: societies that practiced cannibalism faced significantly greater risks of disease, making the behavior harmful to long-term population survival. Please Like, Comment and Follow 'Philip Teresi on KMJ' on all platforms: --- Philip Teresi on KMJ is available on the KMJNOW app, Apple Podcasts, Spotify, YouTube or wherever else you listen to podcasts. -- Philip Teresi on KMJ Weekdays 2-6 PM Pacific on News/Talk 580 AM & 105.9 FM KMJ | Website | Facebook | Instagram | X | Podcast | Amazon | - Everything KMJ KMJNOW App | Podcasts | Facebook | X | Instagram See omnystudio.com/listener for privacy information.

A study is claiming that armed civilians often stop active shooters with fewer casualties than police interventions. The authors attribute this advantage to civilians already being on scene and being harder for attackers to identify. The findings are presented as support for concealed-carry rights, though the conclusions remain controversial within broader debates over gun policy and public safety. USA Today reports that rumors about England using Viagra to combat Mexico City's altitude were false. Thomas Tuchel dismissed the claim, while Jordan Henderson joked about it before clarifying he wasn't serious. The underlying issue is real, though: England faced a significant altitude challenge at Estadio Azteca, where the thinner air can affect player performance and endurance. The medical examiner concluded that Helen Massiell Garay Sanchez died from hypothermia after spending the night inside a walk-in freezer at a Miami Dollar Tree store, with alcohol use contributing to her death. Investigators found no evidence of foul play, but her family is pursuing a wrongful-death lawsuit against the retailer seeking $50 million in damages. Reuters reports on a study by researchers from Poland and the Czech Republic that explored why cannibalism became one of humanity's strongest taboos. Their conclusion: societies that practiced cannibalism faced significantly greater risks of disease, making the behavior harmful to long-term population survival. Please Like, Comment and Follow 'Philip Teresi on KMJ' on all platforms: --- Philip Teresi on KMJ is available on the KMJNOW app, Apple Podcasts, Spotify, YouTube or wherever else you listen to podcasts. -- Philip Teresi on KMJ Weekdays 2-6 PM Pacific on News/Talk 580 AM & 105.9 FM KMJ | Website | Facebook | Instagram | X | Podcast | Amazon | - Everything KMJ KMJNOW App | Podcasts | Facebook | X | Instagram See omnystudio.com/listener for privacy information.

Jogadores da Bélgica fazem a chamada "dança de Trump" e o Viagra que afinal não foi usado pelos ingleses!

In this episode we are joined by one of the most hilarious media personalities, Laura Mbatha, as we talk about everything happening in Nairobi. Enjoy!

Pilot crashed his plane into a skyscraper in China for "personal reasons". Wildfire betting site sparks arson concerns in California. English soccer team approved to use Viagra for their Mexico City match.Weird AF News is the only daily weird news podcast in the world. Weird news 5 days/week and on Friday it's only Floridaman. SUPPORT by joining the Weird AF News Patreon http://patreon.com/weirdafnews - OR buy Jonesy a coffee at http://buymeacoffee.com/funnyjones Buy MERCH: https://weirdafnews.merchmake.com/ - Check out the official website https://WeirdAFnews.com and FOLLOW host Jonesy at http://instagram.com/funnyjones - wants Jonesy to come perform standup comedy in your city? Fill out the form: https://docs.google.com/forms/d/e/1FAIpQLSfvYbm8Wgz3Oc2KSDg0-C6EtSlx369bvi7xdUpx_7UNGA_fIw/viewform

Make Cazarre enchaîné great again de 16h30 à 17h30 en direct du Flora Caffé avec Julien Cazarre & Jean-Christophe Drouet.

Guys, check out b-Vibe's 360 Plug — the male equivalent of the rabbit. It's a remote-controlled vibrator with 360° rotation, a smooth silicone body, and simultaneous prostate and perianal pleasure. Grab yours at bvibe.com and use code TABOO25 for 25% off!Erectile dysfunction affects tens of millions of men in the U.S., yet stays wrapped in silence and shame. In this episode, I bust the biggest ED myth — that it's a permanent, unfixable part of aging — and walk through the full range of treatment options available today. I cover penile implants, vacuum erection devices, testosterone replacement therapy, and FDA-approved medications like Viagra and Cialis, then move into natural approaches: therapy, lifestyle changes, key nutrients, and sex toys that keep intimacy alive during treatment. I close with a look at emerging treatments on the horizon — shockwave therapy, stem cells, PRP, and gene therapy — and a clear call to action: talk to your doctor, because ED is treatable and no one has to navigate it alone.In This Episode:00:00 — bvibe 360 Plug (code TABOO25)00:50 — Podcast Intro / Welcome to Taboo to Truth01:10 — Welcome Back + ED Stats01:55 — What This Episode Will Cover02:15 — Myth-Busting: ED Is NOT a Permanent Part of Aging03:00 — Treatment #1: Penile Implants04:05 — Treatment #2: Vacuum Erection Devices (Pumps)05:00 — Treatment #3: Testosterone Replacement Therapy (TRT)05:50 — Treatment #4: FDA-Approved Medications (Viagra, Cialis, Levitra, Stendra)06:35 — Natural Approaches: Counseling & Sex Therapy07:35 — Lifestyle Changes & Key Nutrients (Citrulline, Vitamin D/E, Zinc)08:20 — Sex Toys: Staying Intimate During Treatment09:10 — The Future of ED Treatment (Shockwave, Stem Cells, PRP, Gene Therapy)10:05 — Fastest Way to Fix ED + Key Takeaway11:00 — Outro: Subscribe + Hotter, Wiser, Wilder CourseWant a deeper look? Watch the full episode on YouTube for a more visual experience of today's discussion. This episode is best enjoyed on video—don't miss out!

In this episode of MENO with Jacqueline Buckingham, we sit down with Board-Certified Urologist and Sexual Medicine Specialist Dr. Rachel Rubin to discuss why hormone therapy is a fundamental element of women's healthcare. Dr. Rubin challenges the historical stigma surrounding hormones, explaining that past concerns were often based on flawed data from synthetic products that are no longer standard practice. She advocates for an individualized approach to hormone therapy where patients are empowered with information to make the best decisions for their specific goals, whether they are seeking relief from hot flashes, prevention of osteoporosis, or improvement in libido and sexual function. The conversation delves into the specific benefits of various hormone treatments: ➡️ Vaginal Hormone Therapy: Dr. Rubin describes low-dose local vaginal hormones (estrogen or DHEA) as highly effective, evidence-based treatments for symptoms like dryness, pain, and urinary urgency. She notes these treatments are safe for most women and can reduce urinary tract infections (UTIs) by more than half. ➡️ The "Female Viagra": Dr. Rubin refers to vaginal hormones as the equivalent of "female Viagra" because they improve blood flow to sexual organs, enhancing arousal and making orgasms better. ➡️ Systemic Hormone Therapy: The discussion covers whole-body hormone therapy—including estrogen, progesterone, and testosterone—which can be administered via patches, rings, or creams to address a broader range of menopausal symptoms. ➡️ Mental Health Connection: Dr. Rubin highlights the "amazing benefit" of hormone therapy in managing anxiety and depression that often emerges during perimenopause. ➡️ Bioidentical Hormones: She clarifies that there are FDA-approved bioidentical hormones available that are both safe and often covered by insurance. ➡️ Jacqueline and Dr. Rubin also discuss pelvic floor rehab, the neurological connection between the spine and sexual organs, and how patients can find knowledgeable specialists to build their own "medical pit crew". RESOURCES The Menopause Society: menopause.org ISSWSH (International Society for the Study of Women's Sexual Health): isswsh.org American Physical Therapy Association (for Pelvic Floor Therapy): apta.org ABOUT MENO MENO is the definitive platform for menopause and perimenopause care — connecting women to trusted experts, solutions, and support https://joinmeno.com/ https://www.instagram.com/join.meno https://www.tiktok.com/@join.meno Follow our Founder/CEO on Instagram @jacquelinebuckingham Disclaimer: MENO is for general information and entertainment purposes only and does not constitute the practice of medicine in any way. MENO does not constitute professional health care services or medical advice. No doctor/patient relationship is formed as a result of this podcast. The use of information on this podcast or materials linked from this podcast is at the user's own risk. The content of MENO is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard getting medical advice for any such medical condition they may have and should seek the assistance of their healthcare professionals for any conditions. Learn more about your ad choices. Visit megaphone.fm/adchoices

The antidote to a boring sex life isn't trying harder, it's trying something new together — Take the quiz at arya.fyi and use code: TRUTH15 for 15% off their guided intimacy subscription at https://arya.fyi/start?rfsn=8333683.c9f861In this episode of Taboo To Truth, I sit down with Sabrina Johnson — founder, president, and CEO of Daré Bioscience — to tackle a question that's been 27 years overdue: where is the female equivalent of Viagra?Sabrina breaks down the critical distinction between libido (desire, the mental appetite for sex) and physical arousal (the body's blood flow response), explaining why the two require completely different solutions — and why the pharmaceutical industry has largely ignored the latter in women. She shares the science and story behind Dare to Play, a topical sildenafil cream engineered with proprietary Dermaflex technology to deliver the active ingredient directly to genital tissue, enhancing physical arousal sensations within 10–15 minutes.We cover how Dare to Play compares to existing options like Addyi, Vyleesi, and testosterone — and why none of those address physical arousal the way this does. We also clear up a common misconception: this is not a lubricant. It works from the inside out, enhancing the body's natural lubrication response through increased blood flow.Sabrina walks us through exactly how to get a prescription today — via your own provider or a free telehealth consult— and explains the pricing: $99/tube, 10 doses, roughly $10 per use. Currently out of pocket (no insurance), but intentionally priced for access.This is Part 1 of a two-part conversation you won't want to miss.In This Episode:0:00 – Ad: Aria.FYI0:55 – Welcome to Taboo to Truth1:30 – Meet Sabrina Johnson, CEO of Daré Bioscience2:15 – Libido vs. Physical Arousal: What's Actually the Difference?5:15 – The Real Reason There's No Female Viagra (Until Now)8:15 – Introducing Dare to Play: Sildenafil Cream Engineered for Women10:15 – How to Get a Prescription Today (Free Telehealth Consult)13:15 – What Does It Cost? The $99 Tube, $10 Per Use Breakdown15:15 – Dare to Play vs. Addyi, Vyleesi & Testosterone17:15 – Is This a Lubricant? No — Here's the Key Difference18:50 – Part 2 Is Coming — Subscribe NowWant a deeper look? Watch the full episode on YouTube for a more visual experience of today's discussion. This episode is best enjoyed on video—don't miss out!About The Guest:Sabrina Martucci Johnson is a seasoned life sciences executive and passionate advocate for women's health innovation. As Founder, President,and Chief Executive Officer of Daré Bioscience, Inc. (NASDAQ: DARE), she leads a purpose-driven biopharmaceutical company dedicated to developing and commercializing novel, differentiated products for women. Under her leadership, Daré advances a diverse pipeline spanning contraception, fertility,menopause, sexual health, and vaginal health, with the goal of accelerating access to important therapies. Her leadership has been honored by Ernst &Young Entrepreneur of the Year (Pacific Southwest Region), Fierce Pharma'sMost Influential People in Biopharma, and inclusion on the Medicine MakerPower List and Endpoints Women in Biopharma. Driven by the belief that women deserve better options, Ms. Johnson champions innovation to transform how women worldwide experience their health and well-being.Connect with Sabrina Johnson:Website: https://darebioscience.comDARE to PLAY™ Sildenafil Cream: https://daretoplaybio.comInstagram: https://www.instagram.com/darebioscienceAbout The Host:Karen Bigman, a Sexual Health Alliance Certified Sex Educator, Life, and Menopause Coach, tackles the often-taboo subject of sexuality with a straightforward and candid approach. We explore the intricacies of sex during perimenopause, post-menopause, and andropause, offering insights and support for all those experiencing these transformative phases.This podcast is not intended to give medical advice. Karen Bigman is not a medical professional. For any medical questions or issues, please visit your licensed medical provider.Looking for some fresh perspective on sex in midlife? You can find me here:Email: karen@taboototruth.comWebsite: https://www.taboototruth.com/Instagram: https://www.instagram.com/taboototruthYouTube: https://www.youtube.com/@taboototruthpodcastSubstack: https://karenbigman.substack.comLINKS, EXCLUSIVE VIP DISCOUNTS, COURSES & FREEBIES

Former California game warden John Nores reveals the hidden war being fought deep inside America's forests — where cartel-run marijuana farms have taken over remote public lands, poisoned wildlife, stolen water, and turned California's mountains into dangerous territory. In this episode, John breaks down how Mexican cartel growers set up massive hidden weed farms, how they camouflage camps and irrigation systems, why game wardens became involved in marijuana raids, and what happened when his team came face-to-face with armed growers in the woods. We also discuss the environmental destruction caused by illegal grows, toxic pesticides, cartel tactics, California legalization, the black market, and why this problem is still far from over. John Nores is a former California Department of Fish and Wildlife game warden and author of Hidden War, where he documents his years tracking cartel activity in America's wildlands. Topics include: Cartel weed farms, California forests, game wardens, illegal marijuana grows, Sinaloa cartel, toxic pesticides, water theft, wildlife destruction, armed growers, and the hidden war on public lands. Go Support John! Book: https://www.johnnores.com/hidden-war.html Website: https://www.johnnores.com/ This Episode Is #Sponsored By The Following: Hims! To get simple, online access to personalized, affordable care for ED, Hair Loss, Weight Loss, and more, visit https://hims.com/connect Prescription required. See website for details and important safety information. Sildenafil is the generic version of Viagra®. Viagra® is a registered trademark of Viatris Specialty LLC. Hims is not affiliated with or endorsed by Viatris. Lucy! Save 20% on your first online Lucy order at https://lucy.co/connect with promo code CONNECT! Join The Patreon For Bonus Content! https://www.patreon.com/theconnectshow 00:00 Intro: California's Weed War 01:00 Meet John Norris: Game Warden Turned Cartel Hunter 04:00 Why Game Wardens Battle Cartels 09:00 Inside Cartel Grow Tactics 17:00 Water Theft & Ranch Infiltration 24:00 Deadly Encounters: Gunfights in the Hills 26:00 This Episode Is Sponsored By Hims 27:58 Cartel Structure & Operations Unveiled 41:00 Cat-and-Mouse: Grow Raids vs Apprehensions 46:16 This Episode Is Sponsored By Lucy 47:52 Cartel Incentives: Who's Growing & Why 55:00 Hidden Health Dangers: Pesticides & Poisons 01:03:00 Environmental Fallout: Wildlife & Water 01:08:00 Legalization Backfires: Black Market Thrives 01:16:00 Chinese Cartels & the Evolving Threat 01:25:00 Why the Legal Market Can't Compete 01:36:00 From Gunfights to Game Wardens: War Stories 01:43:00 Cartels, China, and the Fentanyl Pipeline 01:53:00 Northern Border, Drugs, and the Hidden War 02:03:00 Solutions: Law, Education, & Real Change 02:10:00 Impact of Legalization Laws in Other States 02:12:00 Organic Growers vs Cartels: The Forgotten Warriors 02:16:00 Wrap Up: The Fight for America's Wildlands & Closing Thoughts Learn more about your ad choices. Visit podcastchoices.com/adchoices

JLR plans on attempting to take his Viagra this weekend. Man fell to his death at a concert at Madison Square Garden. DraftKings bets.  

Rover will have marathon details on Monday. Charlie hasn't given up on Hogsback. Lucian Freud painting sells for over $39 million, causing his muses talk about their experience being painted. Would anyone on the show pose nude for a painting? Duji is heading to Connecticut for Nationals. Don't touch the water. Ex-wife spies on her ex-husband and his family through his security cameras. Charlie tracks his friend's location. Would JLR eat a wrapped candy bar that Krystle stuck up her snatch? A town in California is rewarding citizens for reporting illegal fireworks. JLR plans on attempting to take his Viagra this weekend. Man fell to his death at a concert at Madison Square Garden. DraftKings bets.  

JLR plans on attempting to take his Viagra this weekend. Man fell to his death at a concert at Madison Square Garden. DraftKings bets.  See omnystudio.com/listener for privacy information.

Rover will have marathon details on Monday. Charlie hasn't given up on Hogsback. Lucian Freud painting sells for over $39 million, causing his muses talk about their experience being painted. Would anyone on the show pose nude for a painting? Duji is heading to Connecticut for Nationals. Don't touch the water. Ex-wife spies on her ex-husband and his family through his security cameras. Charlie tracks his friend's location. Would JLR eat a wrapped candy bar that Krystle stuck up her snatch? A town in California is rewarding citizens for reporting illegal fireworks. JLR plans on attempting to take his Viagra this weekend. Man fell to his death at a concert at Madison Square Garden. DraftKings bets.  See omnystudio.com/listener for privacy information.

Nitric Oxide Explained: Vascular Health, Exercise Performance, and N1o1 with Dr. Nathan Bryan, international Leader in Molecular Medicine, the first to describe nitrite and nitrate as indispensable nutrients required for optimal cardiovascular health. He details NO as a ubiquitous messenger affecting blood flow, erectile function, cognition, exercise performance, endothelial dysfunction, and aging-related declines in NO production. Bryan explains why PDE5 inhibitors like Viagra prolong cyclic GMP signaling but don't fix NO deficiency, and why beet products often fail due to variable nitrate content and inadequate dosing. He outlines his NO lozenge approach that generates NO gas from sodium nitrite and magnesium ascorbate, plus a fermented beet powder drink (NOBeets), and emphasizes the role of oral bacteria (and harms of antiseptic mouthwash/fluoride) in nitrate conversion. They review published endpoints, including flow-mediated dilation, blood pressure effects, inflammation markers, triglycerides, stem cells, plaque regression, applications to Alzheimer's, glaucoma/microvascular disease, safety/dosing considerations, risks of arginine supplementation, and a dual-chamber topical NO serum developed from wound-healing experience.

TR - Should I tell her I took Viagra???, Spider infestation in the bathroom!!!, Giannis gets traded, and Radar updates us on his coffee thief!!! Listen to Elizabeth & Radar on The Mix LIVE weekdays from 6am to 10am!

It's been a hot minute since George and Mike last recorded an episode!  Surrendering to the inevitable aging process and time itself, George and Mike talk about what life is like in their 50's and how things have changed over the years.   Chugging Pepto, taking Cialis, prostate issues... there's nothing the two don't talk about in his hilarious comeback Season 8 episode.

Could your testicle pain or erectile dysfunction be warning you about something bigger?Many men focus on the symptoms without realizing their bodies may be revealing important clues about their overall health. In this episode, you'll learn why persistent testicular pain should never be ignored, the potential long-term side effects of Cialis and other ED medications, and why erectile dysfunction is often linked to underlying health issues. You'll also discover how simple lifestyle changes may help restore healthy erectile function naturally and improve your overall well-being.Tune in to uncover the hidden messages your body may be sending and learn practical strategies that could help you take control of your health.--------------Key TakeawaysPersistent testicle pain should be medically evaluated.Masturbating without ejaculation typically does not harm the testicles.Cialis and Viagra may have long-term side effects.Erectile dysfunction can signal deeper health issues.Blood flow problems are a common cause of ED.Diet and exercise can improve erectile function naturally.The Mediterranean diet supports better sexual health.Walking daily may help improve blood circulation.Sleep quality directly impacts erectile performance.Addressing the root cause may reduce dependence on ED medication.--------------Resources mentioned:Modern Man CribMediterranean DietGood Morning Wood SmoothieRenew with Dr. Anne--------------Curious about how you can boost your bedroom game and build lasting confidence? Check out the course at getwoodnow.com and start your journey to feeling like yourself again!--------------If you enjoyed this episode and want to learn more and get more tips, subscribe to The Modern Man newsletter for exclusive content delivered straight to your inbox! https://dranne.co/themodernman--------------Follow Me On:InstagramTwitterFacebookTikTokYouTube--------------For all links and resources mentioned on the show and where to subscribe to the podcast, please visit https://truongrehab.com/testicle-pain-erectile-dysfunction-guide--------------Want to regain control of your sex life? It's time to reverse the effects of ED on your life. Join the Modern Man Club and embark on your journey to complete recovery and community.--------------Reveal the FREE treatment most men ignore that solves thousands of erectile dysfunction cases every year, plus the 5 biggest mistakes you must avoid if you want to say goodbye to your ED. Uncover it all in my free eBook, available to download now.https://dranne.co/ebook

On this episode of Our Better Half, we enjoy an in-depth conversation with Dr. Sarah Girardi, a trailblazing urologist and female sexual health specialist with over 25 years of experience. Together, we unpack the often-neglected world of older adults' sexual health. Dr. Girardi connects the physical and urological realities of aging to the broader relational and emotional aspects of intimacy, drawing on her extensive clinical background to bust long-standing myths and advocate for the well-being of her patients. A primary focus of the discussion revolves around the biological realities of aging and the critical importance of proper anatomical education. Dr. Girardi emphasizes that recurrent urinary tract infections (UTIs) in women—regardless of whether they are 20, 60, or 90 years old—are frequently tied to sexual activity, making sexual health history a vital component of standard urological care. Furthermore, she addresses the widespread misconception that painful sex or a compromised sex life is just an inevitable part of growing older that women must accept. Through her practice, Dr. Girardi uses direct, empathetic tools—like using a mirror during exams—to help women understand their own changing bodies and reclaim their sexual vitality. She notes that while physical intimacy changes over time, a lack of compliance from one's anatomy doesn't mean intimacy has to end; rather, partners can discover new ways to pleasure each other beyond standard penetration. The episode also highlights major medical milestones and clarifies the science behind female sexual health treatments. Dr. Girardi discusses the historic November 10, 2025, FDA announcement that officially removed the decades-old black box warning on topical vaginal estrogen, a decision rooted in safety data reviewed during an intensive hearing in September of that year. She explains that topical vaginal estrogen is not absorbed systemically, but instead safely restores a low pH and healthy lactobacillus to the vaginal ecosystem, serving as a powerful defense against life-threatening conditions like urosepsis in older women. Shifting the conversation to non-hormonal desire medications like flibanserin, Dr. Girardi clarifies the public discourse surrounding the "Female Viagra" misnomer. She notes that while Viagra works on a purely physical level by maintaining blood flow to an erection, female arousal and desire operate through complex neural pathways in the brain. Ultimately, Dr. Girardi urges both patients and practitioners to reject a compromised quality of life, navigate past historical fears like the 2002 Women's Health Initiative study, and embrace the healthcare solutions women rightfully deserve. If you want to catch up on other shows, just visit our website and please subscribe! We love our listeners and welcome your feedback, so if you love Our Better Half, please give us a 5-star rating and follow us on Facebook and Instagram. It really helps support our show! As always, thanks for listening!  

In this episode of Tangent Station, hosts Kev and Willis dive into the peculiar recall of Boner Bear Sex Chocolate by the FDA. Disguised as a sweet treat, this chocolate contained the active ingredient from Viagra, causing a stir for its hidden pharmaceutical effects. The hosts humorously navigate through the implications of surprise edible enhancements while highlighting an ongoing theme of bizarre product recalls. The conversation touches on the broader landscape of AI and TQL jobs, showcasing the ever-evolving nature of industries. As they dissect the concept of surprise ingredients, the episode leaves listeners questioning the integrity of novelty snacks.

Erectile dysfunction medications like Viagra and Cialis are more common than ever — but how much do we really know about them? This week on The Dildo Whisperer, we dive deep into the world of ED medications: how they work, why people use them recreationally, the pressures surrounding sexual performance, and the very real health risks that can come with misuse. We also tackle one of the most important harm reduction conversations in queer nightlife and hookup culture: the dangerous combination of ED drugs and poppers. Why is this mix so common, and why can it become medically dangerous so quickly? Along the way, we unpack shame, masculinity, aging, anxiety, porn culture, and the myth that erections define sexual worth. Because great sex isn't about perfection — it's about communication, pleasure, connection, and safety. Come for the hard truths. Stay for the safer sex education. Send the us your sex and relationship questions and maybe you will inspire the next episode of The Dildo Whisperer. We have two ways to reach the show. You can call into our show at 844-695-2766 or you can email us at Askthedw@gmail.com. Follow us on social media @dildowhisperer The Dildo Whisperer is produced by DNR Studios. To subscribe to this show and the rest of the DNR Network of shows including the Cookie Jar Podcast visit: www.dnrstudios

Don't do that.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. Deb Muth 00:00:09 Hi there, how are you? Bob Miller 00:00:10 Excellent! Pedaling as fast as humanly possible, but doing okay. Dr. Deb Muth 00:00:14 Good, good. Well, I’m looking forward to our conversation today. This should be amazing. Bob Miller 00:00:20 Yeah, it should be a lot of fun. Dr. Deb Muth 00:00:22 Yeah, anything that’s off-limits for you in, our conversation? Bob Miller 00:00:28 No. Dr. Deb Muth 00:00:29 Okay, anything you want me to make sure we cover for you? Bob Miller 00:00:33 Well, I mean, is it okay if we put a little plug-in for our software? Dr. Deb Muth 00:00:35 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:36 Yeah. Dr. Deb Muth 00:00:37 Absolutely. Bob Miller 00:00:38 Hey, can we… can we do a screen share? Yes, we can. Yeah, because I want to show you some maps, and… Dr. Deb Muth 00:00:43 Okay. Things like that, yeah, so… Perfect. So just let me know when you want to do screen share. Bob Miller 00:00:48 Okay. Dr. Deb Muth 00:00:49 And yeah, feel free to plug your software wherever you want to. Bob Miller 00:00:53 Okay, well, good. Let me pull up a, a slide for that, and give me one second, I just want to shut the door to my office to get the noise down. Dr. Deb Muth 00:01:01 No worries. Bob Miller 00:01:16 And, how should I refer to you? Dr. Debb? Dr. Muth, what do you like? Dr. Deb Muth 00:01:18 Dr. Deb is great, or Deb, either way, I’m pretty informal, so… Bob Miller 00:01:22 Yeah, and… Bob is fine for me. Okay. Yeah. Yeah, there you go. Why people feel like they need this, son. Special name, it’s like, seriously. Dr. Deb Muth 00:01:33 Right? I agree. Bob Miller 00:01:35 When I work with my clients, it’s like, Dr. Millison, just, just bop, just, just bop. Dr. Deb Muth 00:01:41 Yep, that’s how I am, too. Just call me Deb, it’s good. Dr. Deb Muth 00:01:44 They feel a little awkward with that, you know? They’re not used to that, but… Bob Miller 00:01:48 Alright. And you’re a naturopath, medical doctor. Dr. Deb Muth 00:01:52 A nastropathic doctor and a nurse practitioner. Oh, nice. Yeah, so I got the best of both worlds, right? Bob Miller 00:01:58 Yeah, damn. Okay. Alright, so here we go… There we go. Alright, so I got that ready, and then I will do a, I will do a screen share. I think you’re gonna really, appreciate what we’ve come up with. We’ve come up with the concept of, Cellular CPR. Dr. Deb Muth 00:02:23 Oh, nice! Bob Miller 00:02:24 And that is, construct the cell membrane, Protect the cell membrane. And restore it if it’s damaged. Dr. Deb Muth 00:02:32 Love that. Bob Miller 00:02:34 I love that. Yeah, so that’s what we’re focusing on, and then how, You know, we want to get to the point that, you know, most people think of genetics, they think of, like, 23andMe or Ancestry. Dr. Deb Muth 00:02:44 Yeah. Bob Miller 00:02:45 And then you have the professional geneticists who are looking at, you know, odd things that could create a disease. We’re looking at functional genomics. Dr. Deb Muth 00:02:54 Which is so much better. Bob Miller 00:02:56 Yeah. Are you familiar with what we do here, or… Dr. Deb Muth 00:02:58 A little bit, a little bit. So, it’ll be new to me, too, so I’m excited. Bob Miller 00:03:03 And how much time do we have? Dr. Deb Muth 00:03:04 We have an hour, give or take a little bit on either side. Do you have a hard stop anywhere? Bob Miller 00:03:10 No, no, I put a, I moved my clients around, and I don’t have anybody till, 3.30, so we’re good. Okay. Dr. Deb Muth 00:03:16 Perfect. Alright. Bob Miller 00:03:18 It’s like we’re getting started early as well, so… Dr. Deb Muth 00:03:19 Yeah, we’re getting started a little bit early, so that’s good. Bob Miller 00:03:22 Yeah, I just got my office cleaned up, so… Dr. Deb Muth 00:03:23 Okay, good. All right, are you all set to get started? Bob Miller 00:03:28 I’m good to go, my friend. Dr. Deb Muth 00:03:29 I’m gonna just record a little intro and a little bit of a, hook for people, and then we’ll get started. I’ll ask you to kind of tell us a little bit about yourself, and then we’ll just take this conversation wherever it’s supposed to go. Bob Miller 00:03:39 Okay, you got it. Dr. Deb Muth 00:03:40 Alright, sounds good. So what if the reason you’re not healing isn’t your diet, your supplements, or your labs, but it’s actually your genes? Dr. Bob Miller is uncovering how genetic variants, when combined with modern toxins, explain why some of us stay sick no matter what we try. Today, we’re talking genetic pathways, detox blocks, and the new science every wellness warrior needs to know. Welcome back to Let’s Talk Wellness Now, the show where we uncover the root causes of chronic illness, exploring cutting-edge regenerative medicine, and empower you to heal from the inside out. I’m Dr. Deb, your medical detective, and today, our guest, Dr. Bob Miller, is a true pioneer in functional genomics. He’s a board-certified traditional naturopath and the founder of Neutrogenetic Research Institute. And he’s the leading groundbreaking research on how genetic variants influence chronic illness, inflammation, and detoxification. His work has been recognized on international stages, uncovering links between genetic expression and conditions like Lyme disease, mast cell activation, or MCAS, and mitochondrial dysfunction. I’m so excited to talk to Dr. Bob today. He is gonna reveal some things that even I don’t know about, so I’m excited to learn alongside of you guys. So… Dr. Bob, let’s get started. Tell us a little bit about yourself, and kind of how you got on this journey. Bob Miller 00:05:04 Well, that’s, that’s interesting. I was sort of like a mid-career coming to the natural health field, because in my early 30s, I found myself with a severe case of ulcerative colitis. Bob Miller 00:05:15 And I was in the hospital for 21 days. probably within hours of death, pleading to death. And they told me I’ve got one option, and that is cut out the colon and wear a bag. Didn’t sound like a lot of fun. Dr. Deb Muth 00:05:27 Not an option I would want. Bob Miller 00:05:29 So, you know, the medical folks wasn’t real happy with me, but I said, yeah, I’d like to explore some alternative things.Never thinking that I’d get into this field, and then I just, you know, worked with some herbalists and things that I found absolutely fascinating. So, that’s how I got into this around 30 years ago. And, haven’t looked back since, and just having a… having a blast as we now move into how our genetics impacts things. So, that’s what we’re gonna… that’s what we’re gonna talk about today. Dr. Deb Muth 00:05:58 I’m excited to talk about this genetic thing. When you started over 30 years ago, what kind of patience and problems first inspired you to dig deeper into that root cause healing and kind of get into the genetic piece of it? Bob Miller 00:06:10 Sure. Well, you know, as a… now, I’m in a part of the country called Lancaster County, Pennsylvania, where there’s a lot of Amish and Mennonite, and they gravitate towards these things.So, this is their first thing to do, and that doesn’t work, then they’ll go other routes. So, you know, back then, we just saw typical, you know, a little tired, constipation. You know, a little bit of fatigue, arthritis, those kind of things. But things have changed dramatically over the years, as people are now getting more chronically sick. You know, it’s worse than it’s ever been. And what we’re finding is the, the culprits Primarily is mold exposure and Lyme disease. When people get those two together, they’re just… it’s an inflammatory cascade that nobody can seem to unravel. So that’s where we spend a lot of our time. And we’re also spending a lot of time looking at mental health, like ADD, ADHD. And, we give… this year I’ll be speaking at three autism conferences. And we can dig into that a little bit as to why we think we’re seeing such a dramatic increase. And aside from autism, that used to be 1 out of 1,000, now it’s 1 out of 33, or 23. You know, we’re also seeing dramatic increases in ADD, ADHD. People are stressed out. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. And today, I think we’ll have the time to actually go through and show how environmental factors combine with genetics to cause that to happen. So we’ll… we should have a fun visit here today. Dr. Deb Muth 00:07:37 This should be a fun visit. We can cover lots of topics. I am so excited. So, you founded Nutri Genetic Research Institute in 2015. What did you hope to accomplish, and what kind of surprised you in your findings so far about that? Bob Miller 00:07:51 Well, you know, let’s back up at what, you know, genetics is used for. Everybody’s familiar with 23andMe and Ancestry that, you know, tells you where your ancestors came from. Then you have your professional geneticists. I mean, these are people with a degree in genetics. And they’ll look for, you know, very odd sort of things that are prone to relate to a disease. So there are disease-related genetics. Well, in functional, we don’t look at either of those. We look at For example, how you’re breaking down your fats and utilizing them. How you’re recycling your glutathione. How you might be handling your iron. And none of those are disease-causing on their own.And none of those are disease-causing on their own. But when they pile up on you, and then combine that with environmental factors, that’s when things start to go south on us. So, that’s what we’re doing, we’re looking at patterns. And our first foray into this was, we did studies on Lyme disease. And our first foray into this was, we did studies on Lyme disease. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. So, we looked at, like, I think 50 people with Lyme disease. We looked at their genome. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. And we found patterns that were more evident in those with Lyme. Now, this doesn’t… these genetics don’t mean you get Lyme, it just means if you get Lyme, you react worse to it. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. So, as you know, some people get Lyme, they go on a round of antibiotics, and they’re done. Others have a little more struggle, and then others are struggling terribly for years. So there’s an old adage of genetics loads the gun, environment pulls the trigger. Dr. Deb Muth 00:09:14 Yeah, that is so true, and I think when we’re talking about Lyme and mold and things like that, we forget sometimes that our genetics can predispose us to be more sensitive to those things, and if we have genetic pathways where we don’t clear things properly, it’s harder for us to get them out of the body. And then you add on that whole rain barrel effect that we’ve always used as a functional medicine term, right? If the barrel’s half full, you’re okay. If it’s full, and now it’s spilling over, it’s a bigger problem. Have you guys found, too, that some of these environmental things actually are changing the genetics of people, or how they’re processing their own genetics? Bob Miller 00:09:53 Well, let’s go back to, Genetics 101. But we’ll go back a little bit further. So, what an interesting mechanism, what a miracle the body is. Bob Miller 00:10:03 Fats, carbohydrates, proteins, drink water, breathe air, expose the sunlight, and somehow everything gets made. I mean, when you just step back and think about that, it’s like, It’s pretty darn amazing. Dr. Deb Muth 00:10:15 I always tell women, you know, the fact that we get pregnant and we have healthy pregnancies and births is a miracle, because if we had to try to control that, that wouldn’t work so well. Bob Miller 00:10:25 Right. Well, that’s another miracle. These microscopic sperm and egg, human being, 9 months later, it’s like. But even inside of us. We are making our hair, our skin, our nails, our blood vessels, our ATP, our energy, it’s all being created. Well, that gets created by enzymes. So, enzymes take one substance, combine it with something else, and make something new. Then another enzyme comes along and does the same thing. Your DNA is the instructions on how to make the enzymes. So, when we are conceived. If it’s a, if it’s a female, of course, it’s the XX, the two chromosomes. You know, we’ve… everybody’s seen those… the genetics that… Listed pair. So, if it’s a female, the father donated the X enzyme. And the mother has no choice but to give the eggs, so that’s female. If the father donates the Y, you have a male that’s in chromosome number 1. Then 2 through 23 is the rest of the instructions on how to make enzymes. So, what can happen? We can get what are called SNPs, single nucleotide polymorphisms. And SNPs just mean that the instructions to make the enzyme’s not quite as good. So, if one parent gives a SNP on the making of an enzyme, The enzyme’s fine. It works. But, general rule of thumb, It may only work at 70-80% of efficiency. Now, a good analogy is think of an 8-cylinder and a 6-cylinder car. If parents give you good information, that’s like having an 8-cylinder car. If one parent gives you that snip, it’s like having a 6-cylinder car. Now, is a 6-cylinder car a fine car? Sure. It’ll get you from point A to point B, but it’s just going to have the power of an 8-cylinder. Then if both parents give you a SNP on the same enzyme, it may be 30-40%, and that’s like having a 4-cylinder car. Sits in the driveway, looks the same, puts gas in it, everything. But if you’ve got a 4-cylinder car. Probably not a good idea to go cross-country pulling a trailer behind you up and down mountains. Dr. Deb Muth 00:12:29 This is true. Bob Miller 00:12:32 So… We can get an 8-cylinder, 6-cylinder, or 4-cylinder enzyme. Now, if it’s not under a lot of stress, if that 4-cylinder car is just taking you to the bank and the grocery store. It’s just as good as an 8-cylinder car. But if you gotta pull that trailer, and there’s a lot of stress on it, being mountains, it’s gonna struggle. Now, there’s one other little caveat to this, and that is some genetic mutations are gain-of-function. They actually work faster. Now, we have enzymes that do all kinds of things. We have enzymes that make and recycle our antioxidants, but we also have enzymes that make inflammation. No, that’s a good thing, because if we get a virus or bacteria, if you didn’t make inflammation to kill it, well, we’d all die of infection. So, you know, we tend to think of free radicals as bad, antioxidants as good. They both play an important role. But interestingly, some of the major enzymes that make inflammation, they can be overactive. They can be turbocharged. And when they’re stimulated by environmental toxins, they overreact. Bob Miller 00:13:40 And therein lies the problem. When they overreact, we have a problem. Bob Miller 00:13:46 So, if we have genes that overreact when stimulated. And then the enzymes that take care of inflammation are underactive. Then you’re gonna be more inflamed. You know, the majority of people that, you know, come for functional medicine Or naturopathic help, or… Inflammation that they can’t seem to get under control. Dr. Deb Muth 00:14:06 Right. Bob Miller 00:14:07 And we will be, you know, during this hour, we’re going to look at some of the pathways that make that happen. So, what we can do then, we can’t change our genetics. When you’re conceived, that’s the hand you’re dealt. When your life would be over, if someone would take some tissue and measure, it’d be exactly the same as conception. Does it change. Bob Miller 00:14:28 The enzyme’s ability to do its job may be compromised. Because remember I said there’s a, the enzyme takes a cofactor. So an enzyme takes substance A, cofactor, make substance B. Well, if that cofactor’s not there, the enzyme’s not going to work either. So, you could have an 8-cylinder car, and if there’s no gas in it, it’s not going anywhere. So… It’s the strength of the enzyme, it’s the cofactor to do the A to B conversion. And that’s what we’re going to get into. So, many people say, well, where did these SNPs come from? Nobody knows for sure. Sometimes they’re what’s just called de novo, when the sperm and egg go together, the instructions get mixed up a little bit. We do believe a lot of it came from a long time ago, when we were almost wiped out by sexually transmitted diseases. And those STDs were altering the genes when the conception, in other words, when the sperm went into the egg, the STDs were interfering. And causing the problem, so… I often joke, if you want to blame somebody. Blame your great-great-great-great-great-great-great-grandparents for, being a bit promiscuous, so… Dr. Deb Muth 00:15:31 Yeah, for being… having a little too much fun, right? Bob Miller 00:15:35 So, we don’t know for sure, but, you know, there are some that, But most of the SNPs that we get inherit from our parents. So, if you look at a child. And you look at the SNPs. 99.9% of the time, it came from one of the parents. Dr. Deb Muth 00:15:50 In identical twins, do they have the exact same identical makeup? Bob Miller 00:15:54 Yep, Dr. Deb Muth 00:15:56 But not in fraternal twins, correct? Bob Miller 00:15:59 No, no, those could be different, Jeff. Dr. Deb Muth 00:16:00 It could be different because they have different sacs, they’re not sharing that same genetic makeup. Bob Miller 00:16:04 Yeah, so keep in mind, both your mother and your father have, you know, the two And so you get one from one parent, one from another. Dr. Deb Muth 00:16:13 So… Bob Miller 00:16:14 Interesting situation. I had, 3, 3 boys. And, we were looking at an enzyme related to breaking down oxalates. Now, the mother and father each had one SNP, and that’s called heterozygous. Three boys, and they all come together, they’re Amish boys, they’re a lot of fun. And I looked at their genomes, and the one boy didn’t have any SNPs at all. And one had won. And the other one had two. Dr. Deb Muth 00:16:41 Interesting. Bob Miller 00:16:42 So, we don’t quite know how these things get handed off, but with the parents each having one, you could have a child with none, one, or two. So, the one, his ability to break down oxalates, which is fine. The other one was slightly impaired, and the other one was dramatically impaired. So, you can have 3 children, and it all depends what the parents have. Now, if a parent has a homozygous, or 2 copies. And the other parent has nothing. Every child will have one. Okay. If both parents are homozygous, that they both have two, Every child will have two. Dr. Deb Muth 00:17:19 too. Bob Miller 00:17:20 Yes, so that’s the way it works, but, you know, but it’s somewhat rare that both parents are homozygous on an enzyme, but it can happen. Dr. Deb Muth 00:17:27 Do we think that infections today, like Lyme disease or mold exposure, things like that, if the parent, the woman, primarily, I’m thinking, is pregnant, and she actively has these infections. Can those infections affect the genetics, kind of like a past sexual transmission did where we thought back in the day? Bob Miller 00:17:47 Yeah, I… I mean, I’m not that much of a geneticist to answer that for sure, but my thought would be no, that at conception, the pattern’s made. Dr. Deb Muth 00:17:55 Okay. And then that’s… that’s the hand you’re dealt. Bob Miller 00:17:58 Yeah. So, I tell people we have good news and bad news. The good news is we can compensate for the weakness. The bad news is we can compensate for the weakness. Dr. Deb Muth 00:18:09 That is so very true. Bob Miller 00:18:11 Yeah, we can’t, because I often get asked, so we’ll do some things now, and we’ll check my genes again, and they’ll be better. It’s like, nope. Dr. Deb Muth 00:18:18 Oh, – – Bob Miller 00:18:19 You gotta play the hands you’re dealt, so… Dr. Deb Muth 00:18:21 That’s right. Bob Miller 00:18:22 You can test your genetics… if you’re looking at the same enzyme, you can test it every year. It’s not gonna change. It’s like the blueprint. Dr. Deb Muth 00:18:30 It’s good and bad, right? It’s the one test you only have to do once in your lifetime. Bob Miller 00:18:34 No, unless, you know, like, our. Dr. Deb Muth 00:18:36 All the time. Bob Miller 00:18:37 Yeah, now our test looks at, called the Functional Genomic Analysis Test of your genomic Resource. We look at 220,000 steps. Dr. Deb Muth 00:18:46 Wow, that’s a lot. Bob Miller 00:18:47 That’s not all of them. Dr. Deb Muth 00:18:49 Right. Bob Miller 00:18:50 So, maybe in the next year, we’re gonna come out with our third version of the chip. And then, if someone wants to get those new things that weren’t on it, they’d have to repeat. But whatever we measured is gonna stay the same. Dr. Deb Muth 00:19:03 That’s a lot of SNPs to look at. Bob Miller 00:19:05 Keeps us busy. Dr. Deb Muth 00:19:06 But there’s still, but there’s still SNPs that we. Bob Miller 00:19:09 That we’d like to have that we don’t have, so… Bob Miller 00:19:11 We started out with version 1 on our genetic test, then we worked with version 2, and we’re already compiling a list of what version 3 would look like. So if somebody has our version 2, And we’re saying, you know what, it’d be nice if we could see these, well, then you’d repeat, but it won’t change what you already know, so… Dr. Deb Muth 00:19:29 Got it, got it. So, when you started out, and you started looking at the research of Lyme disease and chronic infections, which detox pathways are most important for people who struggle with those conditions? Bob Miller 00:19:43 Okay. You know what might make sense as we do a screen share, and I’ll actually show you the pathway. Does that make sense? Bob Miller 00:19:48 Alright, so… let’s see if I… let me just press the share… Dr. Deb Muth 00:19:52 Yep, you should just be able to press share. Bob Miller 00:19:54 And… number 2. Okay. Are we seeing the screen there? Bob Miller 00:20:01 Okay. Dr. Deb Muth 00:20:02 So, this is a map that we made. Bob Miller 00:20:05 And by the way, this is not… All-inclusive of all the things we look at, but we believe this is a core issue. So, where we’re going to start here, there’s something called the microglia. And the microglia are glial cells. They’re in the brain and the central nervous system. And they’re very interesting little creatures, because most of the time, and this is just a drawing of what they sort of look like. Most of the time, they’re in what’s called the M2 anti-inflammatory mood. What that means, these little guys pick up dirt, debris, Recycle them. Turns on an enzyme called interleukin-10 that’s anti-inflammatory. And just kind of does general housekeeping. And just kind of does general housekeeping. However, when a trigger comes along. However, when a trigger comes along. They… it’s the same glial cell, but it moves over to a very pro-inflammatory enzyme. A pro-inflammatory glial cell. And it triggers these 3 enzymes, Actually, these four. That are pro-inflammatory. Tumor necrosis vector alpha, Interleukin-6. NF Kappa B, Inos. Now, these create inflammation. So you might think, well, why is that good? Well, if you have some foreign invader, virus, bacteria coming in, parasite. If you didn’t have these guys coming to the rescue, you would just die of infection. So, these guys are your friend unless they’re your worst enemy. Because TNFA, and we’ll show you when we actually do a demo account, TNFA can be overactive. So, in other words, it over-responds. Interleukin-6 can be overactive. And if Kappa-B can be overactive. The INOS, and I’ll explain each of these as we go through a demo, can be overactive. Now, what that means is, you’re very good at killing virus and bacteria. But this is where autoimmune disease comes in, and just inflammatory conditions. Now, this is just speculation, but we think what happened is, as you know. Thousands of years ago, we didn’t have refrigeration, we didn’t have sewer, we didn’t have pure water, and we didn’t have antibiotics. So, if you made it to 40, you were an old-timer, because everybody was dying of infection. So, what we believe happened is, by what’s called natural selection, Having these overactive. A thousand years ago was to your advantage. Dr. Deb Muth 00:22:31 Hmm. Bob Miller 00:22:32 But now… We have pure water, we have refrigeration, we have sewers, we have antibiotics. But now we have environmental factors that are stimulating them. Now it’s to our disadvantage. And we’ll talk about that a little bit as it relates to the hemochromatosis genes and maybe the G6PD. Dr. Deb Muth 00:22:48 Yep. Bob Miller 00:22:49 Now, why are we becoming so inflamed? Let’s look at the triggers. Now, one of my, favorite expressions is. I was born all the way back in 1954. Dr. Deb Muth 00:23:01 And it was a different world back then. Bob Miller 00:23:05 These are some of the triggers. And we’ll get into these, but right now, high fructose corn syrup, And the high-fat diet. High fructose corn syrup only came about in 1968. So now we’re being exposed to high fructose corn syrup. Then… we didn’t have these, these viruses like COVID. Dr. Deb Muth 00:23:26 Yeah. Bob Miller 00:23:27 Now, there’s now pretty strong evidence that COVID Was actually, you know, made as a gain of function. It’s debated, and I’m not taking an opinion on it, but there’s some people who believe Lyme disease was also a part of experimentation. Dr. Deb Muth 00:23:40 Go. Bob Miller 00:23:41 Then we have molds, and it appears as though mold is getting stronger. you know, 20 years ago, when I was seeing folks, mold wasn’t on the radar. I would say 7 out of the 10 folks we speak to today have mold problems. Yeah, 20 years ago, we talked more about mold allergy being an issue versus mold toxicity being an issue. Right. So… I know some folks are, you know, speculating what’s happening, but one of the theories out there is that EMF is strengthening mold. I don’t know if you ever heard that theory, and I don’t… Dr. Deb Muth 00:24:13 I have. Bob Miller 00:24:14 I’m not claiming it’s true, but it’s an interesting theory. Then even, you know, your black mold from water-damaged buildings. Then our air pollution is getting worse. We’re getting more toxic metals. Dr. Deb Muth 00:24:26 You know, if we have a… Bob Miller 00:24:27 You know, we’re gonna look back someday and say, what were we thinking, smearing aluminum into our armpits? The, what were we doing putting mercury in our teeth? Then, you know, glyphosate. When I was a kid, there was no glyphosate. So, all of these herbicides and pesticides. Polychlorinated biphenols, And then EMF. So, we love our cell phones, you know, and I think unless you, or in the middle of the desert, or down in a cave, you’re being exposed to EMF somewhere. So, you know, we have our cell phones with us, we have, We have Wi-Fi, the towers are everywhere. And we don’t know long-term, but we may find that this can… this creates some inflammation. And I don’t know if you get any folks, but do you have any folks that have… are they EMF sensitive? Dr. Deb Muth 00:25:16 Oh yeah, we have a whole bunch of them. Bob Miller 00:25:18 Yeah, and then if you have any TBIs, So, plenty of things here. that will stimulate into the microglia, M1. Now, you could say, well. We’re all pretty much exposed to the same thing. Why do some people get hit harder than others? So here’s where we’re gonna start. There’s an enzyme called Nrf2 and RF2. And Nrf2 is the enzyme that senses when there’s inflammation. And turns on hundreds of anti-inflammatory enzymes. We’ll show when we do the demo, you can have genetic weakness on NERF2. And NERF2 inhibits and slows down microglia M1. supports M2. Now, if it’s not complicated enough, there’s an enzyme called KEEP1. And KEEP1 inhibits NRF2. And you can actually have gain of function on keep 1, that makes Keap 1 stronger. So… A lot of the people who land on my doorstep So… A lot of the people who land on my doorstep Both parents gave a mutation on KEEP1, making it overactive. Both parents gave a mutation on KEEP1, making it overactive. Dr. Deb Muth 00:26:31 Hmm. Dr. Deb Muth 00:26:31 Hmm. Bob Miller 00:26:32 Suppressing Nrf2, nerve 2 might be weak. So, nobody’s putting the brakes on, M1. And by the same token, Nerve 2 supports M2. Then there’s a process called mTOR and autophagy. mTOR stands for mammalian tard of rapamycin, the growth of new cells. And then autophagy, taking our dead cells and recycling them. We need a balance between the two of them. If we didn’t have mTOR, the sperm and the egg would never become the baby, the baby would never become the adult, we wouldn’t make new cells. But our cells are constantly, you know, the old cells dying off. Autophagy is where we take that debris from the cell and recycle it, just like a farmer Plows the crop under at the end of the year. The dead plant then becomes the fuel for the spring, your dead cell becomes the fuel for the spring, and that’s autophagy. So we’re gonna look back someday and say, what were we thinking? We give our animals growth hormones so they get fatter faster. Oh my. So, we consume those animals, and inventory runs faster. Now, for anybody who’s, You know, maybe above 40, 45 years old. Think back when you were 12, and what did girls look like? They were primarily flat-chested little girls. Now they look like 16-year-olds. Because environmentally, we’re jacking up mTOR. So, mTOR stimulates microglia M1, suppresses microglia M2. Probably 80% of the folks we visit with. This is the part of the problem. NRF2 is weak. mTOR is strong. Environmental factors come along. And this guy gets carried away. He doesn’t do that burst and move back. Stays here. We’re calling that How environmental factors create a locked-in, pro-inflammatory. and neurotoxic phenotype. In other words, once it starts, it just keeps… Feeding upon itself. Alright, so what happens now when microglia is overactive. it triggers these 3 enzymes, TNFA, N of kappa B, And interleukin-6. Each one of these can have genetics that make them run stronger. Then it stimulates an enzyme called NLRP3, Which makes what are called inflammasomes. Now, guess what inflammasomes can be? Your best friend or your worst enemy? Because they will, if you’ve got, again, a virus or bacteria, or possibly even some bad cells in the body. They will zap them. Well, that’s good. Unless it’s overactive. Unless it’s overactive. And then what it does, through interleukin-1 beta, makes excess glutamate. And then what it does, through interleukin-1 beta, makes excess glutamate. Anxiety, gut inflammation, OCD, ADD, autism. And, you know, glutamate, we’ll talk about that a little bit, but glutamate makes you intelligent, highly motivated go-getter. but can also be excitatory. And then, look what it does. Let’s see, do I have the drawing tool here? Yes, I do. Okay. So, it comes down through here, Makes the glutamate. Comes back up through here. through the ADORA 2A enzyme, Then we’ve got a feedback loop that feeds upon itself. Then, through interleukin-18, we make histamine. and mast cells. And then through histamine receptor site number 1, we come back and spin it. And now you’ve just got this spinning feedback loop. So, the glutamate will make you anxious, the histamine will give you allergies and make you anxious. And you’re allergic to everything, and you’re feeling horrible. Now, it doesn’t end there, Dr. Dad. It then goes on to make something called gast dermins that creates pyroptosis, where it actually starts punching a hole in the cell membrane. And you’re only going to be as healthy as your cells are. Just a little background. You know, we’re made up of trillions of cells, and each one of them has what’s called a lipid bilayer, made from lipids, which comes from fats. And you’re only going to be as healthy as those membranes are. So that’s why we coined an interesting phrase. Cellular CPR. Construct the cell. Protect the cell. And restore the cell membrane. And we believe that’s going to be revolutionary in the functional medicine world. So… It’s not hard to figure out that if you start punching holes in the cell membrane, that’s not a good thing, okay? Bob Miller 00:31:22 Now… There’s an interesting molecule called NAD. Thicotide adenoside dinucleotide. And anybody who’s in the, you know, listening to the health podcasts and things, they’re… They’re, they’re learning about NAD. And I’m going to show you a chart later, all the good things that NAD does, but For the most part, it helps what’s called sirtuins. And sirtuins are quite interesting. If anybody’s looking at longevity. The sirtuins is where they’re looking at.Because sirtuins turn on good things. Turn off bad things. And I’ll show some charts on that later. So for right here, this sirtuin uses NAD, to slow down NF-kappa-B. CERT 2 uses NAD to slow down an ORP3. So, if we’ve got genetic weakness on these, or we don’t have enough NAD, We don’t hold this pathway back. Make sense? Dr. Deb Muth 00:32:24 Yeah, makes perfect sense. Bob Miller 00:32:25 Now, I’ll show this a little bit later. So, people are like, oh, well, I’m gonna start taking some NAD. Dr. Deb Muth 00:32:31 Right. Bob Miller 00:32:32 And there’s functional doctors who give NAD intravenous. It was just this morning, I was talking to a woman who said, Oh my gosh. I went and got intravenous NAD, and it took me a month to recover from that. Dr. Deb Muth 00:32:45 Hmm. Bob Miller 00:32:46 what happens is, and I’ll show this in a little more detail, there’s an enzyme called CD38, that’s stimulated by NF-kappa-B. And it takes NAD, To make intracellular calcium. that stimulates NLRP3 and actually makes things worse. So, if we have this guy upregulated, and I’ll show a chart what does that. taking NAD will make you worse. Again, when I go into the software, I’ll show you that whole pathway, so… I would encourage people, you know, just don’t go out and start taking massive amounts of NAD, you know, stick your toe in the water, see how you do. Because everything you’ve heard about, how good it is, is true, unless this guy says, oh, thank you very much, let me make more inflammation. Now, this might be part of our innate immune system, that if we have some pathogen that’s gonna kill us. By golly, we want that to happen. But if this is happening by environmental factors, Then it’s detrimental. So the immune system that protected us a thousand years ago now might be turning on us because of the environmental factors that we showed earlier. All right. Then there’s an enzyme called PARP that’s NAD-dependent, and that actually repairs strain breaks in your DNA. Now, the next thing that happens… is there’s an enzyme called NADPH oxidase that gets stimulated. and something called INOS. Now, I’m sure most people know about nitric oxide. It’s a gas that dilates your blood vessels. That’s why sometimes they’ll even give people drugs, nitroglycerin, to boost their nitric oxide. That’s why people are doing beetroots and other things to boost their nitric oxide. But there’s an OS3 enzyme that makes the nitric oxide that’s good for blood flow. But there’s an INOS That makes nitric oxide to kill pathogens. probably might be the third or fourth time I’ve said this. That’s a good thing, unless it isn’t. So, if it’s killing some pathogen, great. It was just misfiring. it combines… With superoxide that’s made by this enzyme, and makes something called peroxynitrite, which is one nasty free radical that chews you up and spits you out. So, the NOx enzyme, NADPH oxidase, uses NADPH, To make this free radical called superoxide. If we have time, we’ll get into it. NADPH is what your body needs to recycle your antioxidants.So, I coined the phrase, the NADPH steel. Where the NOX enzyme takes this very important NADPH, And rather than being useful, makes superoxide. Now, again, is that fine if you’ve got some bacteria to kill? Of course. But if it’s just chronically running, it’s just making all this chronic inflammation. Then it makes something called hydrogen peroxide. And we need to clear hydrogen peroxide by 3 enzymes, catalase, thyroid reduction. And glutathione peroxidase. If we have genetic issues on here, or we don’t have the cofactors. There’s something called the Fenton reaction, discovered in 1895 by Dr. Fenton. Where hydrogen peroxide combines with iron to make what are called hydroxyl radicals. And guess what they do? They create lipid peroxides, That damages your cell membranes. Now, again, the body’s pretty darn amazing. We have glutathione, And here’s where your body’s taking glutathione and recycling it. But look who’s needed to recycle it. NADPH. So, if this guy up here is chewing it up, We don’t recycle our glutathione. And then an enzyme called glufon peroxidase 4, Takes this damaged lipid and repairs it. So, here we’ve got this protecting, we want to protect it by not having this happen. But then we also need this guy to do the restoration. So, there’s a lot that can go wrong in here, Dr. Deb. Dr. Deb Muth 00:37:07 There’s a lot that could go wrong. And I can imagine some of my listeners are thinking that lipid peroxidase, is that the same thing as what they’re thinking of when we talk about lipids and cholesterol? Is that the same process that’s happening there? Bob Miller 00:37:22 Well, no, no, the lipids can be used to make cholesterol, but here we’re talking about where they’re going to build the cell membrane. And they’re being… and they’re being, destroyed. If anybody would like to see a visual representation of this, just go on YouTube. And type in, ferrooptosis Animation. cool little video, it’s about 3 minutes long, and it shows the lipids coming over, being oxidized, and now GPX4 fixes them, so… YouTube, Pharaoptosis Animation, cute little video. It’s just that really… Shows vividly what we’re… what we’re talking about here. Now, this is… Dr. Deb Muth 00:37:59 And so this is very common, too. Like, a lot of people do hydrogen peroxide IVs. Dr. Deb Muth 00:38:04 And so, if somebody doesn’t know their genetics, they could have a problem with doing those, just like they could doing the NADHIVs, correct? Bob Miller 00:38:13 Sure, yeah, yeah, yeah. So, I’ve talked to so many, you know, of course, the hydrogen peroxide kills pathogens. I mean, that’s what it does. So… but I’ve spoken to so many people that said. I had one client that said they’ve never been the same after having one hydrogen peroxide infusion. Dr. Deb Muth 00:38:30 Interesting. Bob Miller 00:38:31 Yeah. So… it can be… I see why people use it, because it. Bob Miller 00:38:36 pathogens, But on the other hand. And now’s a good time to speak about… I don’t have it on here, but there’s a, there’s an enzyme called the HFE gene. And that is what causes you to absorb iron. And there’s mutations in it that cause something called hemochromatosis. Were you overabsorb iron? Now, true hemochromatosis is when both parents give you a mutation. But there’s now growing evidence even a heterozygous can cause a little bit more iron absorption, not to the human chromatosis point, but overabsorption. So, if you overabsorb iron, And you have too much hydrogen peroxide that’s not cleared, All kinds of inflammation. Now, what’s happened is sometimes this inflammation Will damage the red blood cells. And some well-meaning doctor says, oh, you need some iron. And they take iron and it makes it worse. So, can’t tell you how many people I’ve said, you’ve got the overabsorption of iron, and they say, well, that can’t be right, because I’m low in iron. Well, that could be because it’s being chewed up here. Dr. Deb Muth 00:39:40 Sure. GPX1 and TXN turn it into, to water. The, catalase turns it into water and oxygen. Dr. Deb Muth 00:39:58 Now, I see a lot of my clients who have mutations or SNPs on that GPX gene, on that glutathione gene. And they really struggle to clear a lot of their toxins. Bob Miller 00:40:12 Sure. Dr. Deb Muth 00:40:14 Yeah, absolutely. Well, GPX4. Bob Miller 00:40:18 is what, repairs, but you can see GPX1 Is what uses glutathione. To turn hydrogen peroxide. So, but it all depends upon having enough glutathione. Dr. Deb Muth 00:40:30 Yeah. Bob Miller 00:40:31 Well, guess who controls making a glutathione? Dr. Deb Muth 00:40:34 Nerf 2. Bob Miller 00:40:37 So, if you have a keep one weakness, or strength to two… I’m sorry, keep one is too strong. Nrf2 is too weak. You don’t make glutathione. So, when a lot of people do that, it’s like, well, I’m gonna take glutathione. Dr. Deb Muth 00:40:51 Right. Bob Miller 00:40:52 And some do great, and some do poorly. You know, because… and I’ll show this on one of the other charts. You can see here that the, The glutathione has to be recycled. And if we don’t recycle it, it actually turns into superoxide free radical. So… NADPH are the cofactors, For taking the oxidi… here’s oxidized glutathione, here’s reduced. So, this is a good glutathione. After it does its job, you can see it becomes oxidized.We need to recycle it. Well, if we have weakness on the enzyme that does that, or a weakness in Nrf2, or not enough NADPH. The oxidized glutathione never gets recycled. So, I’ve talked to a lot of people who said, oh, glutathione made me so sick, and say, well. Dr. Deb Muth 00:41:43 Yeah. Bob Miller 00:41:44 You need it, but you need to recycle it. Dr. Deb Muth 00:41:46 Can you speak for just a brief moment, too, about MTHFR? That is a very popular gene, it’s all over social media as the major gene, but can you speak to a little bit about that, and how that fits into this whole process of things? Because it is just such a small piece. Dr. Deb Muth 00:42:04 understanding genetics. Bob Miller 00:42:06 Yeah, to be honest, it drives me nuts. Dr. Deb Muth 00:42:08 Me too. Bob Miller 00:42:11 Alright, so… You know, there are people on social media I won’t say what I think, I’ll be kind. But… But the, And, you know, they might mean well. But they talk about, if you have MTHFR and COMT and PEMT, that’s… oh my goodness, that’s horrible, and we’ll fix that for you, and you’ll be fine. Bob Miller 00:42:36 it just irritates me to no end. And it really could get anybody who’s doing this legitimately in trouble. I mean, I’m afraid someday, you know, there might be some cracking down on this kind of nonsense. Now, to answer your question about MTHFR. Dr. Deb Muth 00:42:51 I mean, it really is, but I’ll tell you what, why don’t we hold that thought until I go to another map and I can actually… Okay. Bob Miller 00:42:56 But the real… the cliff notes is the MTHFR puts a methyl group on your folate, which is needed, but it has gotten way, way, way too much attention. And people learn they have MTHFR, and they start taking a multivitamin with methylfolate, then they take a B vitamin with methylfolate. Dr. Deb Muth 00:43:13 And they’re pushing it too hard. Bob Miller 00:43:15 Yeah. So I can’t tell you how many people I’ve helped by saying, stop it. Dr. Deb Muth 00:43:20 Yeah, take less of it. Bob Miller 00:43:21 Take less of it, yeah. So, yeah. Yeah, there’s a… If somebody, say, ranked the enzymes at their level of importance, MTHFR might be 40 or 50 on a scale of 100, you know. Keep one Nerf two. big deals. Dr. Deb Muth 00:43:40 deals. Bob Miller 00:43:41 NQO1 that I didn’t even talk about yet, NQO1, takes your, NA… your NAD goes into NADH, To make electrons for the electron transport chain. you need NQ01 to bring that back. If that’s not working, and I’ll show you on the NAD map how disastrous that can be. Now, the next piece is here, and I think You know, if you talk to any school teachers and say, if you’ve taught for more than 10 years, how are the kids today? Every one of them says, more ADD, ADHD, more autism. Just look at human beings, we’ve never been so agitated. You know, everybody, and it might be a social media thing, but people take a position on something, and if anybody doesn’t share that position, they view them as the enemy. Dr. Deb Muth 00:44:29 And it’s kind of scary what’s happening to us. Bob Miller 00:44:33 So, we can’t agree to disagree anymore. We see anybody who has a differing opinion as the enemy. And, you know, there was… there’s people that didn’t have Christmas dinners together, because they had political differences, like… Dr. Deb Muth 00:44:44 Excuse me. Bob Miller 00:44:45 can’t you put your political differences aside to have Christmas together, you know? Dr. Deb Muth 00:44:49 Right? Bob Miller 00:44:50 become that, you know, no matter what your position is, and I’m not saying anyone’s right or wrong, I’m just saying. You know, in the old days, they used to say that the Republicans and Democrats in Congress would argue policy and then go have dinner together. And now everybody’s all up in arms, angry. Dr. Deb Muth 00:45:05 Yeah. Bob Miller 00:45:06 So… There’s likely multiple reasons for that. But let me show you one of them. That, you know, to what degree this is… very important, we don’t know, but I think We’re beginning to believe this is very important. So, there’s something… there’s a neurotransmitter called GABA. And God buys the don’t worry, relax, be happy. Chill. Okay. Dr. Deb Muth 00:45:31 Nobody has enough of that anymore. Bob Miller 00:45:33 Well, yeah, you’ll be surprised what I’m gonna show you. So, let me see if I can find a, Let me see if I can find the right slide here. Let me look for it here. So, there’s something called a GABA receptor site. And here you can see… This is a neuron, and this is where you, The neuron normally is excitatory. However, there’s normally low chloride in the neuron. Dr. Deb Muth 00:46:09 Hmm. Bob Miller 00:46:10 So, GABA itself is neither relaxing. For excitatory, all GABA does, it opens up what’s called a chloride channel. And then chloride, which has a negative charge, will flow into the neuron. Follow me there? Dr. Deb Muth 00:46:26 Yep. Bob Miller 00:46:27 And as it does, it changes this from a positive charge to a negative charge, And it’s relaxing. and inhibitory. Dr. Deb Muth 00:46:34 Hmm. Bob Miller 00:46:36 Now, on the other hand, there’s enzymes called NKCC1, That will push chloride in. and KCC2 that will bring chlor… oops and bring chloride out. And then there’s a sodium channel. And, sodium has a positive charge. And glutamate will push that in. So, as long as this is happening. And GABA says, receptor sites, open, chloride goes in, Chill. However, If NKCC1 Pushes extra chloride in. KCC2 doesn’t pull it out. and GABA hits the receptor site, the GABA comes flowing out, Sodium comes in, And now it’s excitatory. So Gabba didn’t change. GABA just opened the receptor site, that’s all it does. Dr. Deb Muth 00:47:33 Yeah. Bob Miller 00:47:34 But it’s the chloride balance that’s going to determine whether this is relaxing or not. Now, these are the things that go along with when they lose that KCC2 or gain NKCC1. Pain and sensitivity, burning electrical, neuropathic pain. Normal touch hurts. Sound and light sensitivity. Tinnitus can flare. Headaches and migraines. Seizure tendency. Body jolts. Spasticity, cramps, stiffness, startle reflex. Trouble falling asleep, non-restorative sleep. Anxiety, stress, reactivity, that’s what we have now. Hyperarousal, panic-like surges, irritability, racing thoughts. Brain fog, slowed processing, working memory slip-ups. Mental fatigue. Episodes of racing hearts, sweaty palms, guts on edge. Those are all the things that happen when this GABA switch occurs. Now, here’s what happens, and this is what I’m going to be presenting at an autism conference. When you have a newborn, they need that NKCC dominant to develop. By early childhood, it should… or, sorry, early adulthood. we should move over to the KCC dominant, that’s the taking the chloride out. Nice-looking 25-year-old boys, functioning very well. However, when we get microglia M1 upregulated. Because of environmental toxins, processed foods, Tylenol, aluminum. they stay in NKCC1 dominant, and there’s ADD, ADHD, Autism, the whole spectrum. because… They’ve not moved over to the… They’ve not moved over to the KCC2. And again, this is caused by… Environmental factors. Stimulating the microglia. And then, interleukin-1, interleukin-18 weakens KCC2, interleukin-1 beta, Strengthens NKCC1. high chloride. We open up the chloride channel, In Rebell Excitatory. So, I think when, When the pediatricians get ahold of this, they’re going to be very excited to know that This could be why we’re seeing such a rise, and not just autism, but ADD, ADHD, anxiety, the whole shit mess. Dr. Deb Muth 00:49:58 thing. Bob Miller 00:49:59 Yeah, so… and you can see NF-kappa-B stimulates that. These stimulate it, and I think that’s why everyone’s getting so anxious. Now, there’s a little bit more to it, and we’ll get into this when we look at some of the maps, but… The, the glutamate, Which is excitatory. will stimulate the NMDA receptor, make more glutamate, And glutamate will inhibit KCC2. And then we also need an astrocyte To, take both ammonia And glutamate, and… Turn them back into glutamine. And I’m going to talk to you a little bit about arachidenic acid, and if we have too much arachidenic acid. or TNFA is upregulated, that doesn’t happen. Ammonia goes up, and there may be multiple reasons for this, but this is a reason why some of the autistic kids do flapping. Dr. Deb Muth 00:50:49 Hmm. Bob Miller 00:50:50 Because they’re not clearing their ammonia. And you can tell if somebody has high ammonia by… they get that old person smell, you know. Dr. Deb Muth 00:51:00 Yup. Bob Miller 00:51:01 your vehicle cycle’s not taking out the, the ammonia. Now, last pathway here. There’s growing interest in mast cell activation. So, back here, we talked about peroxynitride. And that will stimulate mast cells, and those are white blood cells that are your best friend, unless they’re your worst enemy. Then it’ll make histamine. And there’s enzymes called histidine decarboxylase that’ll make more. Dr. Deb Muth 00:51:28 I’m sure everybody’s heard of DAO, the enzyme that degrades histamine. Yep. Bob Miller 00:51:31 We can have genetic weakness, we don’t make that. There’s an enzyme called histamine and methyltransferase, That, That breaks down the histamine. Then if we don’t do that, it’ll get stuck in the histamine receptor site. And then it’ll make something called, renin. Which will cause angiotensinogen to turn into angiotensin. One, that turns into angiotensin II,And that’s where people make aldosterone, where they’ll get the, The swollen ankles and high blood pressure. But interestingly, there’s an enzyme called ACE2, that takes this guy and turns it into angiotensin 1-7, Which is anti-inflammatory and also inhibits… TNFA. Now, you can have weakness on ACE2, But… and anybody’s saying, that sounds familiar? Dr. Deb Muth 00:52:25 That’s where COVID comes in, using ACE2. Bob Miller 00:52:28 And now we just found there’s literature that if you get COVID long enough, it can actually make ACE2 not be able to work as well. So look what it does. It comes down here, stimulates the NADPH oxidase, More superoxide. More peroxynitrite. And we’re on a cycle here. We’ve actually named this the Home Cycle Hypothesis, the proposed feed-forward loop. That just keeps feeding on itself. All being caused by… Primarily, The environmental factors. But hitting those who have genetic weakness the hardest. That’s why. Dr. Deb Muth 00:53:08 To the people. Bob Miller 00:53:09 Don’t live in a moldy house. One person is sick as can be, and the other person says, well, you must be imagining things, because I don’t feel anything. Dr. Deb Muth Yeah. Same thing with long haul, right? Two people can both get sick, one gets sick and never seems to recover, and somebody else gets sick, and they have absolutely no problems with it at all. Bob Miller 00:53:30 Sure. Well, think about it, if you get COVID, and ACE2 is weak, and some of this other stuff is going on. This thing just starts feeding upon itself. Dr. Deb Muth 00:53:38 Keep creating more inflammation, more complications, nothing’s calming down. Bob Miller 00:53:43 Yeah. Now, you, you ask about, MTHFR. So, this is the, this is the, the software called Functional Genomic Analysis. There’s a demo report we have. So, let’s talk a little bit about, MTHFR. So, we actually have a map called a methylation map. Now, what happens is, when you do your saliva test, you, you know, you spit, you put some saliva. in a collection kit, goes to a lab, takes out the DNA data, sends it to the computer, and now you can actually see it visually. Okay. So, it’s gonna take a second for this, data to load up, it’s, and each of these Circles, each of these ovals, is an enzyme. And the data gets loaded up to see where it is. So, until it gets loaded up here, I didn’t preload this. There it goes. So… The primary thing about methylation is There’s a nasty substance called homocysteine that, if it’s too high, can really be detrimental. The body takes methylfolate, and combines with methyl B12, To bring this back up to methionine. And then through the MAT genes, we make SAMI, S-adml methionine. Which is involved in so many processes. Then after it does its thing, it turns back into homocysteine. And this thing needs to keep spinning around. That’s why, you know, it’s a good idea to keep homocysteine at, do you have a number that you’d like? 7, 8? What do you like for a number? Dr. Deb Muth 00:55:24 Yeah, I like mine below 7. Bob Miller 00:55:26 Yeah. So if the homocysteine goes too high. It, caused all kinds of problems. So, here’s where you ask about the MTHFR. So, here you can see on this individual. I click on MTHFR, and you can see it comes up here, here’s the C677. And you can see here where it says, variants. I’ll… I’ll draw in case somebody’s having a hard time seeing that. So, you can see there’s nothing in there. That means there’s no genetic mutations. If one parent would have given a mutation, there’d be a 1. If both parents did, there’d be a 2. Now, here’s why Yes, methylation is important, I’m not saying it isn’t important, but look at this MTHFRC677. In my software. Only 42.5% of the population does not have a mutation. 44.7% have won. 12.9 have 2. So, this isn’t some rare, oh my god, I’m gonna die… Kind of thing, yeah. Dr. Deb Muth 00:56:27 Right. Bob Miller 00:56:28 So, And then what happens is that, and again, I’m not dismissing methylation, I… we could do a whole show on methylation. Bob Miller 00:56:36 get it. But I think that what people are doing is they’re, they’re learning about MTHFR, they get it measured, they panic. They start taking massive amounts of methylfolate, which many times is to their detriment. Dr. Deb Muth 00:56:50 Well, it’s… and isn’t it true, too, with MTHFR, like, you have to also look at MTR, MTRR, and the more we stack up of those, the more complicated than MTHFR can be. It’s not… it’s not as simple as just saying MTHFR 677 versus 1298. It’s more complex than that, kind of like what you’ve already shown with some of the other things. There’s more to it than just that one little sliver. Bob Miller 00:57:17 Oh, sure, well, let’s take a look. So, remember I said there’s a cofactor? One of the cofactors is called FAD. Just a Bob Miller observation, that’s all. But when people have trouble with their riboflavin and they don’t have enough FAD, They’re doing much worse than people who have just a C677. So, right here, you could have perfect C677th. And if you don’t have the cofactor, it’s not gonna work, okay? Dr. Deb Muth 00:57:48 And as you said, there’s an MTR enzyme. Bob Miller 00:57:51 that takes methylfolate and methyl B12, to spin it around. So, here on this individual. here’s your… here’s your B vitamins, or I’m sorry, your B12s. There’s an enzyme called TCN1 that takes it from the stomach into the blood. Then there’s other enzymes that take it from the blood into the tissue. And if you’re having trouble here. Well, then you’re not going to have this working, so… Even if you don’t have MTHFR, And you have MTR, like this, no, I’m sorry, this person doesn’t. But they have the MTRR, and then they don’t have enough B12, this isn’t gonna work, aside from that. And then there’s a middle pathway. And then there’s enzymes called the MAT1. they take the methionine to the salmon. If that’s not working, we stick… we get stuck in methionine. So, it’s, it’s not just an MTHFR. And then, one of the things that people forget about. is through these CBS enzymes and CTH, We make cysteine, which is needed to make glutathione. The master antioxidant. So, it really is that… I call it the, The 3D chess game played underwater. Dr. Deb Muth 00:59:07 It really is. I mean, I see people who have CVS, COMT, glutathione, MGHFR genes. And some of them function just fine. Like, they have Like, I look at this person and I’m like, oh my gosh, I don’t know how they’re functioning because they’re double mutated on so many pathways, but yet they don’t have a lot of symptoms, they don’t have a lot of complications. Somehow their body has figured out a way to adapt to what it has so it can stay alive and it can function at a high functioning level. Bob Miller 00:59:36 Yeah, and they may be, you know, eating right? Yeah. Staying out of a moldy house. reducing stress. So, it’s diet, it’s stress, it’s genetics, environmental factors. So, yeah, we can’t just say somebody’s gonna be good or somebody’s gonna be bad. You know, some people get scared, oh, I got all these, it’s like, well… Bob Miller 00:59:56 Are you living in a moldy house? You know, and if you live in a moldy house and your glucuronidation pathway doesn’t do well, or if you’re, you know, a smoker, or you’re constantly eating junk food, I mean, all. Bob Miller 01:00:07 things come together. Although, you know, when we focus on genetics, we’re well aware that this is just a piece of it. You know, you could have identical twins, Genetically, and if one… Is exposed to mold and smokes and drinks and stressed out. They’re gonna be a whole lot sicker than their sibling. Bob Miller 01:00:28 Yep. Dr. Deb Muth 01:00:29 Yeah, it’s that concept of taking twins, and one gets raced with one family, and one gets raced with another family, and they don’t have the same… problems that… that each other have, you know? It’s a very unique situation, we don’t think about that enough. Bob Miller 01:00:44 Alright, so again, genetics loads the gun, environment pulls the trigger. So, if you’ve got a loaded gun, but you don’t have the triggers, you’re okay. Dr. Deb Muth 01:00:53 Yeah. Bob Miller 01:00:54 Yeah. So, remember I said I was going to talk about NAD? So, here’s NAD, and what it does, it turns into NADH. And what NADH does, it, Comes down this pathway, what’s called the electron transport chain. And that makes your ATP, that’s your energy. So, if this wasn’t working, we wouldn’t be alive, because we wouldn’t have energy. So it donates an electron, that’s why it’s called electron transport chain. So, we need NAD, To make this, to make the energy. But remember I said that NQ01, this would probably be, like, on my top 10 list of… Bob Miller 01:01:36 Much more important than MTHFR. This one takes NADH back to NAD. If we’re stuck over here, We’re low in this NAD+, But what happens is, NQO1 also provides CoQ10. And CoQ10 Is what’s needed for the electron transport chain to flow. So if we get too many electrons up here. And they don’t turn them into energy. They make a nasty free radical called superoxide. Okay. Now, NAD plus also makes NADPH, And that is needed. Remember I said we need to recycle our antioxidants. So, if we have a problem with FAD from riboflavin. Yeah, we don’t have enough NADPH, Glutathione’s not getting recycled, and you’re gonna be inflamed. And you take glutathione, you’ll feel worse. There’s another enzyme called thimoredoxin. Same thing, needs NADPH and FAD. And same way with your nitric oxide, there’s an enzyme called NOS3, That makes the nitric oxide that dilates your blood vessels. And if we don’t have enough NADPH or fat, You’re gonna make superoxide. Rather than nitric oxide. Now, remember

Jordan's back from Soccer Aid with tales from the dressing rooms. Not to be outdone on dressing room chat, William's been hard at work preparing for his West End debut and has an update on his bevel. The boys also help you with your dilemmas involving changing hairdressers, massage parlour faux pas, and how to confront your partner over his secret stash of Viagra.If you want to get involved you can email us, and for more Sexted fun sign up to our free VIG&Diva newsletter. You can follow us and DM on Instagram and TikTok, and watch the latest episode every Tuesday and Friday on YouTube.Help I Sexted My Boss is presented by William Hanson and Jordan North. It is an Audio Always production. Hosted on Acast. See acast.com/privacy for more information.

This is Part 1 of a five-part miniseries on Tim Griesheimer's life. Tim is by far one of the most popular guests we've had on the show, so this series dives even deeper into his life featuring new stories about gang life, prison, identity, trauma, and redemption. In this episode, Tim shares the early chapters of his life, from growing up in an abusive household to finding acceptance in the streets, gang culture, and eventually prison. Tim opens up about what it was like being white while running with mostly Black friends and Blood gang members, how racial dynamics differed between Ohio and Texas, and the controversy around using the n-word. He also describes childhood violence, early crime, carrying guns as a kid, shootouts, and how he became drawn to the outlaw lifestyle before his first prison sentence. Topics include: -Growing up in Ohio and Texas -Childhood abuse and street life -Being white around Blood gang members -Saying the n-word and facing consequences -Early gun violence and shootouts -Racial tension in Texas -First experiences with prison politics -Finding identity through crime and gang culture Go Support Tim! IG: https://www.instagram.com/tattoos_bykriminalkustoms/ This Episode Is #Sponsored By The Following: Hims! To get simple, online access to personalized, affordable care for ED, Hair Loss, Weight Loss, and more, visit https://hims.com/connect Prescription required. See website for details and important safety information. Sildenafil is the generic version of Viagra®. Viagra® is a registered trademark of Viatris Specialty LLC. Hims is not affiliated with or endorsed by Viatris. Join The Patreon For Bonus Content! https://www.patreon.com/theconnectshow 00:00 From a Troubled Home to the Streets 01:01 Introducing Tim Griesheimer's Story 04:47 Connecting with People and Early Social Traits 07:09 Nature vs. Nurture and Developing an Outlaw Mentality 10:27 Embracing the Streets: Stealing and Early Crimes 13:01 Fighting, Survival, and Street Cred 17:08 Shootouts and Guns at a Young Age 21:12 Gang Affiliations: Bloods, Crips, and Neighborhood Politics 25:48 This Episode Is Sponsored By Hims 27:38 Reflecting on Gang Life, Family Bonds, and Military Ambitions 33:13 Childhood Abuse and Family Trauma 36:50 Violence at Home and Resentment Toward Parents 41:13 Cycles of Abuse: Family History 43:14 Moving Between States & Unstable Upbringing 45:27 Culture Shock: Racial Dynamics in Texas vs. Ohio 48:00 Experiencing Prejudice from Both Black and White Communities 50:01 First Time Going to Prison – Facing Reality 54:01 Arrival at the Most Dangerous Texas Prison 56:11 Navigating Prison Politics and Racial Pressure Learn more about your ad choices. Visit podcastchoices.com/adchoices

its not a joke anymore. im on the roof and its not funny anymore. im green. Hims connects you with licensed healthcare providers online, giving you simple access to legitimate ED options from home. No awkward appointments, no pharmacy lines.Just complete a simple online intake, and a provider will review your information to determine if treatment is right for you. If prescribed, your treatment ships directly to your door in discreet packaging.That includes Sildenafil, also known as Generic for Viagra®, available through Hims at up to 95% less than the brand-name version. And if that option isn't right for you, there are additional treatment options available—so you can find what works best for your body.Get HimsSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

On this week's episode, Will helps Scotty with the sound board, and JP does not like it. Is Derek's absence overrated or underrated, and what are some taglines for Viagra. where is the weirdest place you have done the dirty and could you have s dead battery smoke doctor in your house? Enjoy another episode and keep on laughing.

Former federal inmate Eric King joins to expose what life is really like inside ADX Florence, America's most notorious supermax prison. After being sentenced to 10 years for firebombing a politician's office in 2014, King says he endured brutal treatment in federal custody, including beatings, starvation, solitary confinement, four-point restraints, and years of communication restrictions. In this episode, Eric opens up about his radicalization in Kansas City, the Ferguson protests, his federal case, surviving violent prison politics, fighting a guard in self-defense, winning at trial, and later being sent to ADX Florence in what he believes was retaliation. He also explains the psychological toll of extreme isolation, the myths surrounding ADX, how prisoners communicate inside, and what it took to rebuild his life after release. Eric is the author of A Clean Hell: Anarchy and Abolition Inside America's Most Notorious Dungeon, a firsthand account of survival, resistance, and humanity inside the federal prison system. Topics include: -Eric King's childhood and political awakening -Ferguson, direct action, and his federal charges -Violence, solitary confinement, and prison retaliation -Life inside ADX Florence -The psychological effects of extreme isolation -Reentry, trauma, family, and healing after prison Go Support Eric! Book: https://pmpress.org/index.php?l=product_detail&p=1872 IG: https://www.instagram.com/supportericking/ This Episode Is #Sponsored By The Following: Hims! To get simple, online access to personalized, affordable care for ED, Hair Loss, Weight Loss, and more, visit https://hims.com/connect Prescription required. See website for details and important safety information. Sildenafil is the generic version of Viagra®. Viagra® is a registered trademark of Viatris Specialty LLC. Hims is not affiliated with or endorsed by Viatris. Cash App! Download Cash App Today: https://capl.onelink.me/vFut/1ekoiacn #CashAppPod. Cash App is a financial services platform, not a bank. Banking services provided by Cash App's bank partner(s). Prepaid debit cards issued by Sutton Bank, Member FDIC. See terms and conditions at https://cash.app/legal/us/en-us/card-agreement. Cash App Green, overdraft coverage, borrow, cash back offers and promotions provided by Cash App, a Block, Inc. brand. Visit http://cash.app/legal/podcast for full disclosures. Join The Patreon For Bonus Content! https://www.patreon.com/theconnectshow 00:00 Eric King Introduction 02:00 Eric's Early Life & Radicalization 06:00 Growing Up: Crime, Poverty, and Activism 12:00 Losing Faith & Early Legal Troubles 18:00 Protest, Ferguson, and Political Activism 21:06 This Episode Is Sponsored By Hims 22:41 The Crime: Ferguson Response & Arrest 29:00 Prison: First Experiences & Racial Politics 34:00 Surviving Prison Culture & Targeting 40:00 Abuse by Guards & Florence Medium Incident 45:42 This Episode Is Sponsored By Cash App 47:00 Torture, Four-Point Room & Transfer Hell 53:00 Isolation, Violence, and Solitary Life 01:00:00 Fighting Back: Resistance & Prison Protests 01:14:00 Second Trial: Self-Defense, Winning in Court 01:20:00 ADX Florence: Punishment & Reprisal Transfers 01:28:00 Arriving at ADX: Conditions and Isolation 01:37:00 ADX Daily Life & Psychological Impact 01:49:00 Punitive System, Corruption, and Quota Reality 01:56:00 Surviving Isolation: Mental Discipline & Gratitude 02:00:00 Reentry: Life After Prison & Its Challenges 02:06:00 Reflection: Regrets, Growth, and Activism Now 02:12:00 ADX Realities, Mythbusting & Book Release 02:18:00 ADX Procedures, High-Profile Inmates & Closing Learn more about your ad choices. Visit podcastchoices.com/adchoices

How did Ozempic, Prozac, & Viagra get their names?... It's the wild world of drug-naming.Now is the perfect time to ask your landlord to cut your rent… We got the receipts & playbook.Google's Search Bar is history's most profitable feature… But last week it got plastic surgery.Plus, the hot new vacation trend is lights-off… Dark Sky Vacations have never been brighter.$GOOG $NVO $MARNEWSLETTER:https://tboypod.com/newsletter OUR 2ND SHOW:Want more business storytelling from us? Check our weekly deepdive show, The Best Idea Yet: The untold origin story of the products you're obsessed with. Listen for free to The Best Idea Yet: https://wondery.com/links/the-best-idea-yet/NEW LISTENERSFill out our 2 minute survey: https://qualtricsxm88y5r986q.qualtrics.com/jfe/form/SV_dp1FDYiJgt6lHy6GET ON THE POD: Submit a shoutout or fact: https://tboypod.com/shoutouts SOCIALS:Instagram: https://www.instagram.com/tboypod TikTok: https://www.tiktok.com/@tboypodYouTube: https://www.youtube.com/@tboypod Linkedin (Nick): https://www.linkedin.com/in/nicolas-martell/Linkedin (Jack): https://www.linkedin.com/in/jack-crivici-kramer/Anything else: https://tboypod.com/ About Us: The daily pop-biz news show making today's top stories your business. Formerly known as Robinhood Snacks, The Best One Yet is hosted by Jack Crivici-Kramer & Nick Martell. Hosted on Acast. See acast.com/privacy for more information.

Did JLR get his car repairs done? Why do public bathroom toilet seats have a gap in the front? In a new Netflix docuseries Michael Jackson's child molestation Trial is going to be revisited. Rover enjoyed using his bidet at bankruptcy box. Has JLR taken his Viagra?

Did JLR get his car repairs done? Why do public bathroom toilet seats have a gap in the front? In a new Netflix docuseries Michael Jackson's child molestation Trial is going to be revisited. Rover enjoyed using his bidet at bankruptcy box. Has JLR taken his Viagra?See omnystudio.com/listener for privacy information.

B2 has her 1 week follow up. Weiner mobile race. Duji had to buy a new water pump. Charlie's friend saw something shocking in the parking garage. A Tennis pro begs for an emergency bathroom break mid-math during the French Open. A woman was killed by an umbrella while eating at a restaurant. Duji needs to get a car for Gia in the next two weeks. Ferrari just released a new electric car. Did JLR get his car repairs done? Why do public bathroom toilet seats have a gap in the front? In a new Netflix docuseries Michael Jackson's child molestation Trial is going to be revisited. Rover enjoyed using his bidet at bankruptcy box. Has JLR taken his Viagra? During a college woman's softball game on ESPN, Texas vs. Arizona State, a wild comment was heard during the broadcast. Woman who is paragliding is struck by a plane. A woman in Florida passed away after she was attacked by two pitbulls.

B2 has her 1 week follow up. Weiner mobile race. Duji had to buy a new water pump. Charlie's friend saw something shocking in the parking garage. A Tennis pro begs for an emergency bathroom break mid-math during the French Open. A woman was killed by an umbrella while eating at a restaurant. Duji needs to get a car for Gia in the next two weeks. Ferrari just released a new electric car. Did JLR get his car repairs done? Why do public bathroom toilet seats have a gap in the front? In a new Netflix docuseries Michael Jackson's child molestation Trial is going to be revisited. Rover enjoyed using his bidet at bankruptcy box. Has JLR taken his Viagra? During a college woman's softball game on ESPN, Texas vs. Arizona State, a wild comment was heard during the broadcast. Woman who is paragliding is struck by a plane. A woman in Florida passed away after she was attacked by two pitbulls.See omnystudio.com/listener for privacy information.

The response to our first episode on penis performance problems was so big that we knew we had to come back for round two. In this episode, we're getting into the practical stuff: what to do in the moment when things aren't going as planned, how to keep your sex life feeling connected and fun even when performance issues are in the mix, and how both partners can show up for each other without making everything weird.

Patrick Bet-David and Dr Paul Saladino walk through the timeline of modern “quick fix” breakthroughs, from the birth control pill and breast implants to Viagra, GLP‑1 weight loss drugs and the explosion of Botox. Saladino argues the real frontier now is peptides, including GLP‑1s and growth‑related compounds, which can deliver dramatic short term changes but come with poorly understood long term tradeoffs for hormones, muscle, fertility and aging.