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Brethren, this was one of the very first STBs that were sent to every member Lodge in April 1923, and was prepared by Clara Richards. As the future of public education is now a hot topic among the leadership of the United States, it seems like a good time to revisit how our forbears though, […]
In this podcast we try to understand a bit more about the challenge of fixing transport in the North - and how Sub-National Transport Bodies like Transport for the North can help to drive the vital investment required.And yes - I renamed this podcast because feedback suggested the original title "Understanding the role of Sub-National Transport Bodies" was just a little too obscure and not "grabbing" enough! So we start by asking what exactly are Sub-National Transport Bodies (STBs) – what are they, what do they do and why do we need them.STBs were created by the Cities and Local Government Devolution Act in 2016, and there are now seven Sub National Transport Bodies covering different regions of the UK. The intension is to provide strategic transport policy leadership at a larger scale than is possible by the existing local transport authorities or local authorities individually.Of the seven currently in existence, only one - Transport for the North - has been given statutory powers – and as such, from 2018 TfN has been a statutory partner to the Department for Transport, National Highways, and Network Rail to ensure that the North's pan-Northern strategic transport priorities are developed and delivered. The rest, bodies such as Transport for the South East, Transport for the East, England's Economic Heartland, Western Gateway and Peninsular Transport and Midlands Connect operate in shadow form, advising and cajoling but without formal powers to act.That said, they do hold influence and, by bringing together local authorities, businesses, communities and asset owners, they should able to make significant cross border difference in terms of where sone vast sums of devolved and centralised public cash is focussed. But do they in reality? Well to discuss this it is my pleasure to welcome Martin Tugwell to the Infrastructure Podcast. Martin is chief executive of Transport for the North and the former leader of England Economic Heartland so probably knows more about STBs than anyone in the UK! STB Conference - 5th JuneTransport for the North websiteTfN strategic transport plan
Brethren, this Short Talk Bulletin Podcast episode was written by MW Bro Carl Claudy, and first published in December 1938. This bulletin represents the conclusion of the first 16 years of STBs, and celebrates itself as the 192nd such Bulletin. What was begun as an experiment in short, digestible, sugar coated bits of Freemasonry has […]
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2022.11.17.516978v1?rss=1 Authors: Liu, P., RUAN, D., Ye, Z.-W., Yuan, S., Li, Z., Zhang, W., Ong, C. P., Tang, K., Guo, J., Xuan, Y., Tam, T. T. K. K., Huang, Y., Zhang, Q., Lee, C.-L., Chiu, P. C. N., Liu, F., Jin, D.-Y. Abstract: The ongoing and devastating pandemic of coronavirus disease 2019 (COVID-19) has led to a global public health crisis. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and can potentially pose a serious risk to maternal and neonatal health. Cases of abnormal pregnancy and vertical transmission of SARS-CoV-2 from mother to foetus have been reported but no firm conclusions are drawn. Trophoblasts are the major constituents of the placenta to protect and nourish the developing foetus. However, direct in vivo investigation of trophoblast susceptibility to SARS-CoV-2 and of COVID-19 and pregnancy is challenging. Here we report that human early syncytiotrophoblasts (eSTBs) are highly susceptible to SARS-CoV-2 infection in an angiotensin-converting enzyme 2 (ACE2)-dependent manner. From human expanded potential stem cells (hEPSCs), we derived bona fide trophoblast stem cells (TSCs) that resembled those originated from the blastocyst and the placenta in generating functional syncytiotrophoblasts (STBs) and extravillus trophoblasts (EVTs) and in low expression of HLA-A/B and amniotic epithelial (AME) cell signature. The EPSC-TSCs and their derivative trophoblasts including trophoblast organoids could be infected by SARS-CoV-2. Remarkably, eSTBs were highly susceptible to SARS-CoV-2. They expressed high levels of ACE2 and produced substantially higher amounts of virion than Vero E6 cells which are widely used in SARS-CoV-2 research and vaccine production. These findings provide experimental evidence for the clinical observations that opportunistic SARS-CoV-2 infection during pregnancy can occur. At low concentrations, two well characterized antivirals, remdesivir and GC376, effectively eliminated infection of eSTBs by SARS-CoV-2 and middle east respiratory syndrome-related coronavirus (MERS-CoV), and rescued their developmental arrest caused by the virus infection. Several human cell lines have been used in coronavirus research. However, they suffer from genetic and/or innate immune defects and have some of the long-standing technical challenges such as cell transfection and genetic manipulation. In contrast, hEPSCs are normal human stem cells that are robust in culture, genetically stable and permit efficient gene-editing. They can produce and supply large amounts of physiologically relevant normal and genome-edited human cells such as eSTBs for isolation, propagation and production of coronaviruses for basic research, antiviral drug tests and safety evaluation. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Brethren, this Short Talk Bulletin Podcast episode was written by Rev Dr Bro Joseph Fort Newton, and was first published in May 1924. In following with our theme of revisiting some of the first STBs that were sent out to all Lodges across the country, here we find an excellent discussion of that second of […]
Brethren, this Short Talk Bulletin Podcast episode was written by Rev Dr Bro Joseph Fort Newton, and was first published in April 1924. The Square was one of the first STBs sent to all lodges a hundred years ago, the aim being to provide a common stock of vetted Masonic information to all Lodges throughout […]
Selling feels icky for many teachers! Mainly because we've had bad experiences with being sold to ad don't want to be seen as those pushy, manipulative salesy salespeople (that's a lot of sales, I know haha!) And that's why learning how to sell starts with your mindset! We need to get rid of those old stories and beliefs around sales and see selling our services or courses as HELPING. I talk about that and give a few tips on how to sell in this new podcast episode! Enjoy!
Money is a tricky subject for us, teachers. If not to all of us in general! In this episode, I give you some ideas on how to think about managing money in your business so that it can support you and your lifestyle. 1. I talk about how different offers can support your business growth 2. I mention how managing money is going to help you run a more sustainable business 3. I also make a point of investments in business that will support you! Listen now to get inspired on how to have a better relationship with your money!
I know being on social media is a pain. It's forever changing and you probably cannot keep up with the trends. I feel the same. But the opportunities that your online presence and visibility can bring are priceless. 1. Rather than getting stuck at 'I'm afraid to show up' (because perhaps you're scared of judgment?) think 'My online presence allows me to connect with people that I can help!' 2. Rather than comparing yourself with others, think 'I've learned so much about social media already and there will always be so much more to learn' so the only person to compare to is yourself from the past (This reframe was created by my ex-Rocketer Katie!) 3. Instead of 'I'm not interested in social media and have never been active on it', think 'Social media is a free marketing tool that I can use for my benefit and the way I see fit!' And if you want to learn more about being visible and why it's important, listen to the newest podcast episode!
'If people want to study with me, they can just check out my website and see what I offer' Oh I've heard it so many times from teachers that I work with! Teachers assume that if they exist (eg have a website and a social media profile) that's enough to attract paying clients to their business. But then they don't see any results. They just sit and wait and think: 'But all the information is out there!' Well, I could say that that's literally the definition of what marketing IS NOT. Marketing is the art of creating tension, provoking, and making people think! And it needs to be proactive. And that's what I talk about in my newest podcast episode. Have a listen to get inspired on how to market your teaching business effectively!
I know, I know. You want your tips and tricks and how-tos on how to build and scale a teaching business, so will I just shut up about MINDSET. Nope, not gonna happen! Your mindset is EVVVVERYTHING. If things don't go according to the plan, if your launch fails, if you're stressed about money, if you haven't had any students enquiring about lessons, if your content strategy doesn't work, do you know what's going to help? If you do, that's great, because I don't. What I know is that your mindset will HELP YOU DEAL WITH THE CRISIS. So, if you please, let me tell you why and how that's going to work. Listen to this week's episode and let me know what limiting beliefs you still have about yourself or your teaching business!
Here are a few questions I wanted to ask you: How much time do you spend on teaching and how much on admin in your usual week? How much do you hate Mondays or how desperate are you for the weekend in your usual week? How many things do you do manually (invoicing/scheduling lessons/content posting etc)? How many times a week do you sit down to plan lessons and how many bespoke lesson plans do you create? Basically, all I want to know is DO YOU HAVE ANY AUTOMATED SYSTEMS in your business, or do you just go with the flow? Your business should be EASY, AUTOMATED and bring you money and satisfaction. I'm not saying that setting up those systems won't require work but it's definitely worth it! Let me help you by pointing you to the direction of the systems in your business that you need in my newest podcast episode.
Welcome to this new awesome series of short juicy episodes of my podcasts that will teach you the 8 fundamentals of successful teaching business. This week is all about your offers! So many teachers run their social media profiles thinking that their job is to teach people more language. And then hope for the best - aka that students will come knocking at their door when they've seen them teach a few useful expressions... Not really! You need to be clear on YOUR OFFER - what you want your students to pay for. Whether it is 1:1s, group classes, courses, digital programs, or e-books, you need to make sure that they know that something is in store for them! There's no point in collecting random followers if you don't know what you're going to offer to them. So listen to this week's episode to find out: 1. Why it's important to have an offer 2. How it relates to your content on social media 3. How to make sure you're not teaching people for free but attracting paying students 4. How to decide what your offer(s) could be
In honour of one of the most disappointing movies of all-time, we present to you: the most heartbreaking episode of STBS ever... Negative emotions are at an all-time high (or low?), as this episode has frustration, anger, disappointment, melancholy, and downright depression. We kind of treated it like a therapy session, so we hope you can do the same!The Flames are out of the playoffs after some some classic controversy, and Liverpool lost the Premier League title and Champions League Final in back to back weeks.Time StampsHockey: 2:08Soccer: 35:45Weekly Round-Up: 1:00:24 Social MediaInstagram: @slappinthebasssportsTikTok: @slappinthebasssportsTwitter: @slappinthebass
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We've really been doing this for FOUR years now? Time flies! Listen as we flashback to some classic moments of STBS from 2018, from the funny to the downright embarrassing...Also tune in to hear about Carsten's love for Coronation Street, the issues with the NHL All Star Weekend, some hefty hunches in the NFL Playoffs, and the almighty Georgian Calendar!But most importantly, thank you so much for all of the love and support over the past four years and thank you for joining our Slappin' The Bass family! We love you so much and will continue to provide you with mediocre content for as long as it's ordered! Time StampsBirthday Clips: 0:48Hockey: 17:14Football: 37:17Weekly Round-Up: 53:15 Social MediaInstagram: @slappinthebasssports TikTok: @slappinthebasssports Twitter: @slappinthebass
We fully recommend booking a one-way ticket to Ottawa because it is B-E-A-U-T-I-F-U-L! Listen to how our trip was and how bad the Sens are! Also, Canada is no longer a one-trick pony, WE'RE A RUBIK'S CUBE OF TRICKS! Find out why by listening NOW!Time Stamps:Ottawa Review: 2:00Soccer: 25:58Football: 44:32Weekly Round-Up: 54:32Social MediaInstagram: @slappinthebasssports TikTok: @slappinthebasssports Twitter: @slappinthebass
For what seems like the first time in STBS history, the boys are cautiously optimistic about the Flames two weeks in a row! They also discuss the true contenders and pretenders in the NHL and try to calm down some of the overreactions in soccer.If you or someone you know needs help with sexual assault, abuse, or violence, please call the following phone numbers:Calgary Communities Against Sexual Abuse: (403) 237-6905Alberta's One Line for Sexual Violence: 1-866-403-8000Canadian Association of Sexual Assault Centres: 604-876-2622Time Stamps:Flames: 5:52Hockey: 20:06Soccer: 37:12Weekly Round-Up: 56:56Also check out https://ca.movember.com/donate or @movember to donate to support men's health! Social MediaInstagram: @slappinthebasssports TikTok: @slappinthebasssports Twitter: @slappinthebass
The young chaps make their extremely anticipated predictions for the new NHL season! Will they be correct? Probably not. Will they be as bold as ever? Absolutely! Will Carsten ever love Mark? Find out in one of the greatest episodes in STBS history :)Time StampsTrophies: 1:59Hefty Hunches: 15:21Bold Predictions: 37:03Standings Predictions: 45:26Weekly Round-Up: 1:05:44Social MediaInstagram: @slappinthebasssportsTikTok: @slappinthebasssportsTwitter: @slappinthebass
1000 Episodes in Review It's our 1000th episode so we thought it would be fun to go down memory lane. It has been so much fun getting to know all of you. Some we know well and have developed personal relationships with. Others came and went as things in their lives changed. To Industry members, thank you for your support! To our listeners, thank you for subscribing, downloading and listening to our show. It's because of you that we are here today and will be here tomorrow! There was a big gap in our records between 2005 and 2007. We switched to Google Docs in 2007 and have been able to keep everything we wrote archived there. But from memory some highlights were: We became the official podcast of AVS Forum and were introduced to members at their CES Party We had an affiliation with HDTV Magazine Met Mark Cuban (owner of HDNet at the time) and Interviewed the President of Syntax-Brillian at the HDTV Conference in Beverly Hills Dolby Flew us to San Francisco to demo some of their projects they were working on. While there we recorded two shows of their now defunct Dolby podcast Oppo and Monoprice were big supporters of the show early on as was Olevia TVs Sonos - The first real product we reviewed on the show back in 2005 A few of our day job colleagues mocked us for doing a podcast. LOL jokes on them HT Guys TV Tech Timeline Braden (Sony CRT...) -> Panasonic Plasma 480p EDTV -> JVC LCoS 1080p Rear Projection -> Epson 1080p Projector(s) -> (Lots of 4k TCLs) -> Sony 4k LED Ara RCA CRT -> Samsung DLP-> Panasonic Plasma-> JVC Projector-> Vizio 4K TV Optoma UST Reviews of all the Rear Projection TVs from 2007 - JVC HD-61FN97 61" HD-ILA Our bottom line at the time - The JVC HD-61FN97 is an excellent value. It looks great, does a wonderful job with HD content, a great job with DVDs and a pretty good job with standard definition TV. Blacks are good, contrast is solid, colors are excellent and detail is vivid. We try to look for great values to help you (and us for that matter) get a little more out of each hard earned dollar. You'd be hard pressed to find a better looking 61" TV at its price. At an online street price of $2125 this is an awesome TV for the money. It really helps bring the big screen home. Our first mention of home automation was in March of 2007. We wrapped up our discussion with - One day home automation will be standard. We'll wonder what people ever did without them. But for now your options are somewhat limited. You can spend a lot of money to get it custom built and done just right, with a system like Crestron, AMX or Control4, or you can try to put it together yourself if you don't mind the occasional hiccup that comes with a home made system. This can be one of the most fun home projects you've ever worked on. And it lasts forever - it's the gift that just keeps on giving. Our earliest “Kaleidescape Killer” comment was also in 2007 when we showcased a $2500 Linux based machine with full DVR and DVD server capabilities. The company was called Interact-TV and they are no longer in business. Our Top Ten shows in HD from 2007: Ara: American Idol (Fox) Dancing with the Stars (ABC) Football/Basketball/Sports Center/Etc on ESPN Planet Earth/Sunrise Earth (Discovery HD Theater) Lost (ABC) CSI Miami (CBS) CSI (CBS) Bikini Destinations (HD Net) Heroes (NBC) NHL Hockey on HD Net Braden: The Unit (CBS) Las Vegas (NBC) Numb3rs (CBS) Monday Night Football (ESPN) Lakers Basketball on KCAL 24 (Fox) I Shouldn't Be Alive (Discovery HD) Destination HD (Discovery HD) Planet Earth (Discovery HD) CSI Miami (CBS) SlingMedia VS Major League Baseball Issue: Slingboxes infringe on the local cable company's right to broadcast the content. Interactive TV Still not a thing DVDpedia In an attempt to build a video server or “Kaleidescape Killer” out of a Mac Mini Ara used DVDpedia to catalog and display album art and id3 data about his library. It worked OK but was quickly abandoned for Boxee and then eventually Plex. Plex is indeed the Kaleidescape Killer! Vudu Movie Download Set Top Box ($399) - October 2007 What we liked: High quality movies on demand Large selection with more coming every week Easy to use remote and easy menu navigation Up and running in five minutes What we disliked: No lease option to defray $400 entry price Not a large selection of Dolby 5.1 Downloads interfered with VOIP telephone service Bottom Line: This is the best home video on demand system the HT Guys have seen. The video quality is first rate! The user interface is clean and simple. You will have the system up and running in no time. All of this is with the initial release of the system software. With more movie releases coming, HD, external storage, and new software updates this product will only get better. At $400 for the Vudu box its not for everyone, but you will get a very good video on demand system for the investment. HDDVD - Bluray - a comparison Conclusion Blu-ray clearly has an advantage in specs, higher storage capacity and higher maximum bitrate. HD-DVD seems to hold the edge in "market readiness" if that's a real term. All the features you want were required in the spec from the beginning, so you know your player supports it. Man it would be nice if the studios would create discs in both formats so we didn't have to buy two players... Netflix Watch Instantly Technology Minimum Requirements Computer running Windows XP with Service Pack 2 or higher, or Windows Vista Internet Explorer version 6 or higher Windows Media Player version 11 (DRM version 5145) or later An active broadband connection to the Internet 1.0 GHz processor 512 MB RAM 3 GB free hard disk drive space Recommended in addition to minimum requirements An active broadband Internet connection of at least 1.5 Mbps 1.5 GHz processor 1 GB RAM The Death of Rear Projection TVs - Jan 2008 Harmony One Universal Remote - As with any Harmony remote, the One is a great choice for your home theater. It's new, sexy and easy to use. The touchscreen is cool and the larger buttons make it a bit easier to use. But overall it doesn't represent a huge departure from the 880. Of course we're gadget freaks, so we'll both be using them, but if you want to save some money, the 880 remains a great option. Bang for the buck, the 880 is still probably the way to go. For the coolness factor, the One is where it's at. Mobile Digital TV Standard - Although ATSC 3.0 has a provision for this most people are just using IPTV over the Cell Networks Orb Speaker Review - we did a review of these cool spherical speakers that sounded pretty good at the time. The cost for a 5.1 system was $1597 in June of 2008. The company is still around and today you can get an improved 5.1 system for $740. Is TidalTV the Next Big Thing? - a new service that mimics the Cable or Satellite experience over the Internet. So the answer is No and Yes! This was in 2008 Popcorn Hour A-100 Review Not a week goes by that we don't hear something about the Popcorn Hour A-100 network media player. We tried relentlessly to get a demo unit for review, but to no avail. Finally, slightly weary but committed whole-heartedly to the show, Ara decided to pony up the cash and purchase one. It arrived last week and we got a chance to play with it. All in all, not a bad little unit. If you want an inexpensive network media player that can play anything, the Popcorn Hour is the best we've seen so far. It requires some IT expertise to get it up and running and to use it on a day-to-day basis, but it works like a champ. Even streaming 1080p HD content over the network looked good, granted it was all that was happening on the network at the time, but it still looked good. If you want something with a little more visual appeal, stick with AppleTV, the PS3 or the Xbox 360 (or Vudu when it adds local network playback). But all of those options are a bit more expensive and not quite as flexible. Vudu HDX Movies Black Friday Roundup 2008 Panasonic Viera 50" 720p Plasma HDTV 899.99 min 10 per store Sony 40" 1080p LCD HDTV & Sony Blu-Ray Player Bundle (Model # KDL40V4100 and BDPS350) - $1,199.98 Sony Blu-ray Player (BDP-S350) -- $179 (with a firmware upgrade and a 1 GB USB stick this will be come BD Live Compliant) Mitsubishi 65" Home Theater 1080p DLP HDTV (Model # WD65735) - $1,199.99 IPTV - Can it replace Cable and Satellite? Note- This was us just talking about the subject LONG (2009) before it was even dreamed of in it's current state - If you had to, you could cut the cord between you and your cable company and not miss a beat. But in reality if you won't have the same video quality. The other thing to consider is that the Cable or Satellite box has an simple well understood interface. Connecting a computer to the TV requires using a keyboard and a mouse and there are no channel numbers. You'll have to bookmark your sites. Companies like Apple, Netflix and Boxee are all trying to provide a ten foot interface that is Grandma proof but we still have a ways to go. Finally, cable companies are not going to be happy with subscribers that watch a lot of Internet streamed content. So even if the quality improved you may not be able to stream a months worth of TV into your home. If you are a light TV watcher that is computer savvy then you may be able to cut the cable cord completely. But in actually, for most of us, IPTV is a good way to augment what we already have. If you are on the road you can watch something on your terms. If you forget to record something then its a great backup. Its also a great way to watch old TV shows that are no longer aired. What if AppleTV Replaced my DVR? The concept at this point in time was to buy subscriptions to your favorite TV show. But as we see today, that's not even required. Plus we now have boxes from Apple, Google, Amazon and Roku. It's safe to say that the AppleTV type STBs have replaced the DVR Zune HD The Zune HD is a powerful portable media device. It has a beautiful OLED screen, small form factor, smooth touch screen menus, and wonderful 720p output to a TV. However, for Microsoft to steal some iPod users, more apps and video content need to be available in the Zune Marketplace. The Zune HD has solid hardware that is almost as sexy as the iPod. What would make this device perfect for a home theater would be Hulu and Netfilx support. Microsoft has also stated that they will release games for the Zune HD, since Xbox Live and the Zune Marketplace already seem to be linked, the possibility of it being a good portable gaming device are great. The Zune HD is a solid device. With future updates it may take a run at the iPod's dominance in the market. RedEye Universal Remote Control (MSRP $190) 2010 - This remote eliminated the need to be in the same room with your gear and will work with your iPod Touch or iPhone. LED TV Technology was just coming on the scene in 2010 Quartics(2010) Quartics Inc. is a semiconductor company based in Irvine, CA, with offices in India, China and Taiwan. Quartics was formed in 2003 to focus on semiconductor architecture for video-based media, aiming to overcome a raft of modern digital challenges. To date, the company has been granted 10 patents, with 40 pending, in media processing architecture, video and graphics processing and QoS algorithms. We don't know if these patents were sold or even used. But the company does not seem to be in business any longer Life|ware Today as part of our ongoing series on home automation we discuss Life|ware. Life|ware™ is software developed by Exceptional Innovation that allows you to seamlessly merge control of your home along with your world of digital entertainment. Life|ware lets you control your home through your TV with a Media Center PC, Media Center Extender or Xbox 360™, from your home or office PC or notebook, or from a Life|point touch screen. You can even use your iPhone or iPod Touch and iPad as a Life|ware client with full two-way functionality. One of the biggest draws to Life|ware is that it works with numerous third party devices. Life|Ware provides bridges to lighting, HVAC, Media and more. The system will go from IP to IR, RF, or RS-232. Life|ware is OS agnostic as well. The control software will run on Windows, Mac OS, and LINUX machines. But if you don't want to mess with loading the software on your own equipment Life|Ware sells a complete line of home automation controllers, servers, and bridges. We can't find a trace of this company any longer. It may have been sold or merged Are High End Audio/Video Retailers a Dying Breed? “If the AV business cannot more clearly illustrate why specialty audio is in fact special, then expect more stores and regional chains to fold in the coming months even as the economy improves, simply perhaps fueled by the fact that mainstream home theater gear is just too good.“ Crystal LED HDTV Technology So when can I have one and how much will it cost? Sony isn't answering any of these questions. Our hunch is that it will cost about what an OLED TV will cost. And if Sony wants this technology to have a chance it needs to come out at about the same time as OLED. We know that Samsung will be releasing their OLEDs in the second half of the year. Our prediction is that you will be able to buy a Crystal LED TV from Sony by the summer of 2013 and it will run about $6,000. The best we can tell is that this tech never made it into consumer TVs. Sony still has a page dedicated to it but more in the commercial side of it's business. Revolv Home Automation Hub 1/2013 The beginning of the “Year of Automation” The best we can tell is that Revolv was bought by Nest and lives on in their products Conclusion When we first learned about a device that could unify all the various home automation and control devices out there we were sceptical. But after putting the Revolv Home Automation Hub through its paces, we can say, yes you can control everything regardless who makes it. Well maybe not everything yet. But we are sure the engineers at Revolv are working diligently to make that happen! Is a 7.1 System Worth it? Bottom Line - A properly installed 7.1 system with 7.1 content will take your home theater to the next level. You will definitely be able to hear a difference, especially with good content like the movie Super 8 . However, if you are not watching Blu-rays or your room doesn't support proper placement of the rear surround channels, a better approach would be to upgrade your 5.1 system or just save the money. This was from 2013. Consistent with our ATMOS recommendations too Netflix SuperHD (6/2013) Netflix SuperHD claims to provide superior 1080p video quality for the same price as regular streaming. But not everyone is eligible. Requirements Netflix Super HD requires an internet connection with at least 5Mb/s download. Not all devices can play Super HD. Super HD is only available via Internet Providers that are part of the Open Connect network. Supported devices include Sony PlayStation 3, Apple TV with 1080p, Roku with 1080p, Nintendo Wii U, Windows 8 App, TiVo Premiere DVR Blu-Ray Players, Smart TV's, Home Theaters, and Streaming Players with existing Netflix 1080p support Bottom Line Netflix is really pushing the streaming frontiers and they have come a long way. We can now sit on our couch on any given evening and find a high quality movie at a moment's notice. We anxiously await the day when we will be able to stream Blu-ray quality movies whenever we want. From what we have seen that day is not too far away! Is Blu-ray a Dead Format? Also from 6/2013 Ask anyone who knows something about home theater what is the highest quality audio and video available to mere mortals today and they will tell you Blu-ray. Blu-ray video is stunning and the audio is simply amazing. But we don't have to tell you that. So does Blu-ray have a future? The following are some reasons why Blu-ray may not be around for too much longer. . . . Time to Bury Blu-ray? Its probably too early to put the last nail in the Blu-ray coffin right now. There needs to be one or two more paradigm shifts before Blu-ray goes away. The first is the studios realizing that DRM is more hassle than it is worth. Once this hurdle is crossed in-store Kiosks or online downloads will soar. Prices will come down and the world will be saved from all that plastic being created. The second is a jump in online speeds. Once gigabit Internet is ubiquitous there will be a shift to storing content in online lockers and again the world will be saved. The big question is when? Based on what we are seeing we are betting on within 5 years. ZyXEL 500 Mb/s Fast Ethernet Powerline Wall-Plug Adapter We reviewed almost a dozen powerline Ethernet adapters. They never achieved their advertised speeds, but they did work and depending on what you needed them to do they were an excellent solution. However, with faster mesh network Wifi it's not really a thing any longer. Aereo In April of 2014 we interviewed a broadcaster who opposed our stance on Aero's business plan. He felt Aero was making money off of the local broadcasters. We felt Aero was providing a service to allow us the viewer to watch our local stations. The Courts agreed with the broadcaster. But today we have Locast. And so far they have been in business for a couple of years. SmartThings Home Automation Hub And so continues the many years of “The Year of Automation”. This was before Samsung bought the company. A full year after we kicked off the “Year of Automation” Pono Player (1/2015) Neil Young's "high resolution" PonoPlayer is on sale for $400. PonoPlayer, a triangular portable music player that promises only the highest of fidelities. We were Skeptics from the beginning: The point is that you don't need fancy hardware to make music sound good, and that no amount of hardware will make your ears hear better than the limits of biology and physics. Ara's first DIY Speaker project was in Jan 2015 Axiim Q Wireless Home Theater System 2/2016 The first Wisa system we reviewed. We are happy to say it's still around today! Conclusion Many of our listeners have asked us to recommend wireless solutions for their home theater over the years. We have tested and rejected all but a few and the acceptable solutions still required some speaker wire from an external amp. Not exactly wireless! The Axiim Q Wireless Home Theater System is the first one that delivers on the promise of a truly wireless system that is simple to install, looks fantastic and sounds great! We hate having to send it back! It would be so easy to bring 5.1 to your master bedroom that we are seriously thinking about buying one! What is HDR? (4/2016) To Sum it Up Getting the best picture from an HDR TV will require HDR content. To guarantee your TV will support HDR look for the “Ultra HD Premium” label. If you really want a UHD TV that does not have the “Ultra HD Premium” label buy a TV that has or comes close to 1000 nits brightness. HDR from cable, satellite, and OTA are still a bit off. We will stop here in 2016 because we'll save some for the next 1000 shows. Along the way we have had dozens of interviews, product reviews, buying guides, and lists that were not mentioned in this episode. Some weeks we struggled to come up with show ideas, some weeks we had too many. But we always managed to have a show ready for your Friday morning commute.
If you want to hear the biggest tangents in STBS history, then please listen to one of the funniest episodes we've ever recorded!P.S. We love all of you so so so much
Disgruntled is a word being thrown out there a lot these days. Can someone really be disgruntled and frat? Find out who is the most frat player in the NHL on this week's episode of STBS.P.S. Thank you to all of our international listeners!!!
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.10.01.322750v1?rss=1 Authors: Stürner, T., Castro, A. F., Philipps, M., Cuntz, H., Tavosanis, G. Abstract: Dendrites display a striking variety of neuronal type-specific morphologies, but the mechanisms and principles underlying such diversity remain elusive. A major player in defining the morphology of dendrites is the neuronal cytoskeleton, including evolutionarily conserved actin-modulatory proteins (AMPs). Still, we lack a clear understanding of how AMPs might support developmental phenomena such as neuron-type specific dendrite dynamics. To address precisely this level of in vivo specificity, we concentrated on a defined neuronal type, the class III dendritic arborisation (c3da) neuron of Drosophila larvae, displaying actin-enriched short terminal branchlets (STBs). Computational modelling reveals that the main branches of c3da neurons follow a general growth model based on optimal wiring, but the STBs do not. Instead, model STBs are defined by a short reach and a high affinity to grow towards the main branches. We thus concentrated on c3da STBs and developed new methods to quantitatively describe dendrite morphology and dynamics based on in vivo time-lapse imaging of mutants lacking individual AMPs. In this way, we extrapolated the role of these AMPs in defining STB properties. We propose that dendrite diversity is supported by the combination of a common step, refined by a neuron type-specific second level. For c3da neurons, we present a molecular model of how the combined action of multiple AMPs in vivo define the properties of these second level specialisations, the STBs. Copy rights belong to original authors. Visit the link for more info
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.07.28.224857v1?rss=1 Authors: Park, P., Kang, H., Georgiou, J., Zhuo, M., Kaang, B.-K., Collingridge, G. L. Abstract: The synaptic tag and capture (STC) hypothesis provides an important theoretical basis for understanding the synaptic basis of associative learning. We recently provided pharmacological evidence that calcium-permeable AMPA receptors (CP-AMPARs) are a crucial component of this process. Here we have investigated two predictions that arise on the basis of CP-AMPARs serving as a trigger of the STC effect. Firstly, we compared the effects of the order in which we delivered a strong theta burst stimulation (TBS) protocol (75 pulses) and a weak TBS protocol (15 pulses) to two independent inputs. We only observed a significant STC effect when the strong preceded the weak TBS. Second, we found that pausing stimulation following either the sTBS or the wTBS for ~20 min largely eliminates the STC effect. These observations are exactly as predicted for a process that is triggered by the synaptic insertion of CP-AMPARs and provide a framework for establishing the underlying molecular mechanism. Copy rights belong to original authors. Visit the link for more info
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.04.29.069005v1?rss=1 Authors: Gallyer, A. J., Dougherty, S. P., Burani, K., Albanese, B. J., Joiner, T. E., Hajcak, G. Abstract: Suicidal thoughts and behaviors (STBs) are thought to be the result, at least in part, of abnormalities in various neural systems. Event-related potentials (ERPs) are a useful method for studying neural activity, and can be leveraged to study neural deficits related to STBs, but it is unknown how effective ERPs are at differentiating various STB groups. The present meta-analysis examined how well ERPs can differentiate those with and without suicidal ideation (SI), suicide attempts (SA), and those determined to be at different levels of suicide risk, or suicidality. Our meta-analysis included 192 effect sizes from 24 studies. We used a random effects meta-analysis and found a small-to-moderate relationship between ERPs and STBs. However, we also found evidence that the literature may be suffering from small sample publication bias. Our results suggest that ERPs may compliment other approaches, such as fMRI, in the study of the neurobiology of individuals with STBs. However, the clinical utility of ERPs to predict STBs remains to be tested, and larger samples are needed to confirm the results of the present meta-analysis. Copy rights belong to original authors. Visit the link for more info
Put this episode in the history books as the Ottawa Senators crack the Top 20 of the NHL Power Rankings, many sports are being played without spectators and the boys share some very special news that belongs in the hearts of every Slappin' The Bass Sports fan!
Every few months, I remind my partners of something that took me way too long to learn.I say, “When a person believes in what they're doing – even if it's an imperfect plan – let them keep doing it. Give them advice and try to open their eyes, but don't fight them too hard, because, ‘A person convinced against their will, remains unconvinced, still.' So be careful. If you finally convince a person to quit doing what they believe in, and to start doing what you would do if you owned their company, they're probably going to fail.” People who have spent time with me may find this difficult to believe, but I'm a lot less combative than I used to be. Here is the non-combative technique I use.Listen attentively to the person with whom you disagree. Let them speak until they're finished. Find a point of agreement, something you can honestly endorse. Tell them why you agree with them. And if they have altered your opinion in any way, confess that to them, as well. Use the point you agree upon to introduce another point which you feel might expand and enrich their perspective. Don't misunderstand me. I'm not talking about introducing “alternative facts.” I'm talking about introducing your idea as a logical extension of the idea about which you have already agreed. This will cause the other person to feel like they already knew the thing that seemingly just occurred to you. In essence, you'll be giving them an entirely new perspective while reinforcing what they already believe. Bottom line: Try to avoid telling people they are wrong. You'll make more progress and achieve more change if you can figure out a way to tell them they are right. Here's a recent example:An air conditioning client was convinced that we should target the perfect customer profile by using “addressable TV” ads. This would allow us to target specific households individually – rather than as a demographic, geographic, or psychographic group – by using data provided by broadcaster set-top boxes (STBs) and over-the-top (OTT) streaming devices like Apple TV, Google Chromecast, Roku, or Amazon Firestick. The CEO of the air conditioning company said, “Why should we pay to reach people who live in apartments, or who rent their houses from landlords, or who have a home warranty contract with a company other than ours? Wouldn't it make more sense to target ONLY those homeowners living in houses old enough to need a new air conditioner, and who don't have a home warranty?” “I love that idea!” I said, “And we've already got some great TV ads we could air!” I gave him a high five, then asked, “How much did they say it will cost us?” “They said it will be extremely efficient since we'll be aiming a rifle with a scope instead of using a shotgun like we're doing now.” “I don't doubt that a bit,” I said, “but we do need to find out how much they're going to charge us per 1,000 households they deliver (CPM.) We're currently paying a cost-per-thousand (CPM) of $3 on broadcast radio. Now I'm DEFINITELY willing to pay more than $3 per thousand to reach the PERFECT customer rather than the unfiltered, mixed-bag, untargeted customers we're currently reaching, but how many untargeted customers is one PERECTLY TARGETED customer worth? Is it 4-to-one? 7-to-one? Are we willing to trade 10 untargeted customers for 1 targeted customer? How many are we willing to trade? I think at some point there's going to be at least one perfect customer in our current, unfiltered assortment of broadcast TV viewers and broadcast radio listeners, don't you think? And then we get all those other people for free. But I still think this “addressable TV” thing is a great idea. So call and tell them exactly who you want to target and ask for the cost-per-thousand.” After he checked into it, he learned that the cheapest we might possibly pay was 12x to 16x our current cost-per-thousand, but with the layers of targeting he wanted to add, we would be trading at least 26 broadcast...
S H O W – N O T E S Warum meckern nichts bringt Was Du von Deinem Steuerberater (Stb.) erwarten kannst Was Du selbst leisten musst, damit es läuft Wann sprichst Du mit Deinem Steuerberater? Sprichst Du mit Deinem Steuerberater auch nur über die Vergangenheit? viele Steuerberater nennen sich auch Unternehmensberater jedoch arbeiten nicht alle entsprechend oft wird von der Vergangenheit bis heute geplant als Unternehmer musst Du von jetzt in die Zukunft schauen das ist eine ganz andere Perspektive ein Steuerberater hat nicht die Kernaufgabe Dein Unternehmensberater zu sein steuerlich kannst Du in der Vergangenheit etwas verändern unternehmerisch jedoch nicht Wie kannst Du Deinen Stb. zu Deinem Komplizen machen? sei schnell mit Deinen Buchhaltungsunterlagen so kannst Du den Betrachtungszeitraum reduzieren für Mittelständler sind nur zwei Größen wichtig! 1. Gewinn 2. Cashflow wieviel willst Du pro Monat steigern? 5%, 10% oder 100% wenn Dir Dein Ziel klar ist, kannst Du die Aktionen dazu planen plane Deine Aktionen monats/ maximal quartalsweise mache Deinem Stb. deutlich was genau Dein Bedarf ist Welche Daten brauchst Du wirklich? vielleicht hat Dein Stb. sogar spannende Kontakte für Dich fordere Dir mehr Input von Deinem Stb. ein erfülle aber vorher Deine Pflichten gehe auf Deinen Stb. zu finde heraus wo Dir Dein Stb. helfen kann da wo seine Expertise aufhört, suche Dir Profis in den Bereichen prüfe ob es spezialisierte Stbs. in Deiner Branche gibt dank der EDV ist eine Datenübergabe recht einfach 3 Schlüsselpunkte Mache Deine Hausaufgaben und bereite alle Unterlagen vor prüfe genau Deinen Bedarf ab suche Dir den für Dich passenden Profi Ressourcen und Referenzen Hier geht es zur 7-Tage-Challenge Kontakt: rayk@codu-training.de Alle Folgen findest Du unter: codu-training.de/podcast Der Beitrag 65: Was Du wirklich mit Deinem Steuerberater bereden solltest erschien zuerst auf Rayk Hahne Unternehmerwissen in 15 Minuten codu.
This week a new boat crashes onto the island. Harley Matthews joins the Padre to talk about his journey of beginning a new kind of faith community. Listen in as they talk about tattoos,punk rock, and the power God to work when we get out of the way! As always there is laughter and stoories that will hopefully reveal something new to us all. Padre's Pods, Episcopal, Interfaith, Spiritual, Holy Spirit, St'Bs, The Brewery, Punk Rock, Tattoos, Alt Lifestyle, Faith, Formation, Christianity, Jesus, God, Maloney,Fr. Sean
In this episode the Padre is joined by supermom Kim Gray. Kim brings here expertice as a teacher and mother of 4 to the mic. Together they talk about the importance of lent for kids and how parents can get them involved in the season. As always there are plenty of laughs and fun along the way. As aways don't forget to share thoughts or questions with us on our facebook page. https://www.facebook.com/pages/Padres-Pods/1395494267368503 padres pods,episcopal, maloney, lent,st.bartholomew's,st.b's,family,faith,spirit,christianity,teaching,children
Human cytomegalovirus (HCMV) is the major viral cause of congenital infection and birth defects. Primary maternal infection often results in virus transmission, and symptomatic babies can have permanent neurological deficiencies and deafness. Congenital infection can also lead to intrauterine growth restriction, a defect in placental transport. HCMV replicates in primary cytotrophoblasts (CTBs), the specialized cells of the placenta, and inhibits differentiation/invasion. Human trophoblast progenitor cells (TBPCs) give rise to the mature cell types of the chorionic villi, CTBs and multi-nucleated syncytiotrophoblasts (STBs). Here we report that TBPCs are fully permissive for pathogenic and attenuated HCMV strains. Studies with a mutant virus lacking a functional pentamer complex (gH/gL/pUL128-131A) showed that virion entry into TBPCs is independent of the pentamer. In addition, infection is blocked by a potent human neutralizing monoclonal antibody (mAb), TRL345, reactive with glycoprotein B (gB), but not mAbs to the pentamer proteins pUL130/pUL131A. Functional studies revealed that neutralization of infection preserved the capacity of TBPCs to differentiate and assemble into trophospheres composed of CTBs and STBs in vitro. Our results indicate that mAbs to gB protect trophoblast progenitors of the placenta and could be included in antibody treatments developed to suppress congenital infection and prevent disease.
In this episode the Padre is joined by Matt Wise once again. After a brief interlude on A&M football they Dive into looking at New Year's resolutions and Baptism. They discuss how people of faith live a cycle that is always calling us look at ourselves deeply. The guys look at popular iagary around baptism and what it means to wade into the waters of faith.
This week I am joined by Everett Lees for a discussion on the holiday movies we have all grown up. Listen in as we look for deeper truths in the stories of Ebeneezer, Rudolph, Clark, and Cousin Eddie. Spoiler alert, if you haven't seen these movies your missing out!
Lisa Mason joins the Padre this week for a discussion of the war on Christmas. The conversation meanders from shopping to commercials to Charlie Brown. Listen as they wade through the distraction to try and find a way to keep the season bright.
This week the Padre sits down with Jamie McAdams to discuss the difficulties of waiting. We discuss the impatience we struggle with and how Advent just might be the season to help us with that. The guys also talk about how Santa may help us come to a deeper understanding of what it means to wait for Jesus. The guys also get a little riff in about resposibility and what it means to live into our choices.
The Padre sits down with Jared Cramer, Aaron Evans, and Matt wise for a discussion of the misunderstood seasonn of Advent. Listen to the guys as they share their traditions and struggles with the season leading into Christmas. As a bonus, you get to hear the sultry tones of Aaron as he proclaims the virtue of the Counting Crows theology.
The Padre talks to Jonathan Wickham (fellow Padre) about the nature of bullies. It's a timely look at Jonathon Martin and Richie Incognito. The roles of sin and brokenness and our responsibility to the process. Sean even takes a little guff about cmparing music and sports.
In this inagural episode of Padre's Pods we hear the origin story of the podcast. Listen in as the Padre talks about the importance of these kinds of stories and sets us up for future episodes.
Title: The Next Generation Cable Network: DOCSIS 3.0 Intro: The first DOCSIS standard, short for Data Over Cable Service Interface Specifications, standard was released by the company Cable Labs in 1997. In this podcast we take a look at the history of these standards and discuss DOCSIS 3.0 – the emerging standard in the cable industry. Mike: Gordon, can you give us a brief history of the first DOCSIS standards? Gordon – just covers up to 2.0 Mike: What are “tiered services?? Tiered services is business jargon for providing a service (such as telecom connectivity or cable channel service) according to separate, incrementally distinct quality and pay levels, or "tiers." We’re seeing this term used a lot recently in political debate regarding “net neutrality?. Mike: Can you tell us a little more about DOCSIS 3.0? Sure – in a nutshell it’s bigger, better, faster… It’s a needed response to products from competitors like Verizon with FIOs FTTH product and AT&T with the FTTN Lightspeed product. It’s triple play broadband – voice video and data. DOCSIS 3.0: - Much higher bandwidth through channel bonding - Starts at 160 Mbps Downstream, 60 Mbps Upstream and goes up from there - TI just rolled out their Puma 5 chip set a couple of weeks ago for cable modems. The chipset supports new DOCSIS 3.0 features, such as channel bonding, enable ultra high downstream bandwidth rates of at least 160 Mbps in the residential data and voice services configuration and 320 Mbps in video and business services configuration. In addition Puma 5 also supports greater quality of service with IPv6 and security with Advanced Encryption Standard (AES). - Multiple 6 MHz (or 8 MHz) channels are bound, treating them logically as one Channel bonding in both upstream and downstream - IPv6 for advanced networking capabilities - Expanded address space (2128 or 3.4 dodecillion) Improved operational capabilities Mike: How will IPv6 be rolled out? There’s a lot of speculation now but it looks like it will be in to phases. John T. Chapman and Shalabh Goel from Cisco Systems have an interesting piece we’ve got linked in the shownotes (http://www.cable360.net/ct/sections/features/20942.html ) “The initial deployment phase allows the cable operator to set up an IPv6 control and management plane for managing the cable modems, set-top boxes, and multimedia terminal adapters (MTAs) with a cost-effective upgrade. In a subsequent deployment phase, cable operators can offer IPv6 directly to the home network. Many new devices are already IPv6 capable, and cable operators could soon be running the largest IPV6 networks in the world.? Mike: What are some other key features of DOCSIS 3.0? Other key related DOCSIS 3.0 features, which may be migrated over time, include: • Enhanced security, including advanced encryption standard (AES), security provisioning and theft of service features; • An upstream frequency range extension to 85 MHz and a downstream frequency extension to 1 GHz that allows an operator to add existing capacity with plant upgrades at a later date; • Enhanced plant diagnostic features, including a cable modem diagnostic log, enhanced signal quality monitoring, extension of IP data record (IPDR) usage and capacity management. Mike: How about the commercial services? (from: http://www.cable360.net/ct/sections/features/20942.html) DOCSIS 3.0 specifications define two technologies for business services over DOCSIS: layer 2 virtual private networks (VPNs) and T-1 circuit emulation. Business users will be able to videoconference from their PCs and PDAs and tap into corporate networks through VPNs; residential customers will subscribe to video-on-demand (VOD) and IP telephony services with low latency and minimum packet loss; and users everywhere will be able to upload and download files at much greater broadband speeds. Mike: When will it be available? Comcast demo’ed 150 Mbps at the May 14, 2007 Cable Show in Las Vegas. “The Associated Press described a demo in which a 30-second, 300MB television commercial was downloaded in a few seconds, while a standard cable modem took 16 minutes?. “Also downloaded, in less than four minutes, was the full 32-volume Encyclopedia Britannica 2007 and Merriam-Webster’s visual dictionary. With a standard cable modem, that download would have taken three hours and 12 minutes (dialup would have taken 2 weeks)?. “Comcast is currently trialing this in the Boston area. In one trial, the cable operator will set up an IP video headend to experiment with carrying voice, video and data over a single IP connection?. According to FierceIPTV (http://www.fierceiptv.com/story/comcast-to-trial-docsis-3.0-iptv/2007-05-08 ): “Comcast's planned converged-services trial will take place in a system that serves 50,000 homes, and will include an IP-video headend and DOCSIS 3.0 STBs, as well as the Slingbox from Sling Media, dual mode WiFi-cellular handsets and mobile phones capable of playing video.? According to Chapman and Goel: The industry consensus is that fully compliant DOCSIS 3.0 CMTS* implementations will be available in 2008 to 2009. Many cable operators will require the most critical DOCSIS 3.0 features, such as downstream channel bonding and IPv6, far earlier. To meet this demand, many vendors’ CMTS products now include early implementations of such a subset of DOCSIS 3.0 features. * CMTS: A cable modem termination system or CMTS is equipment typically found in a cable company's headend, or at cable company hubsite and is used to provide high speed data services, such as cable internet or Voice over IP, to cable subscribers. In order to provide these high speed data services, a cable company will connect its headend to the Internet via very high capacity data links, also known as a circuit (canonical form of telecommunication circuit), to a network service provider. On the subscriber side of the headend, the CMTS enables the communication with subscribers' cable modems. Different CMTSs are capable of serving different cable modem population sizes - ranging from 4,000 cable modems to 150,000 or more. A given headend may have between half a dozen to a dozen or more CMTSs to service the cable modem population served by that headend. One way to think of a CMTS is to imagine a router with Ethernet interfaces (connections) on one side and coax RF interfaces on the other side. The RF/coax interfaces carry RF signals to and from the subscriber's cable modem. (source: http://en.wikipedia.org/wiki/CMTS )