Podcasts about ever known

This is an article from the Raised By Woops Substack. "Everyone You've Ever Known is a Little Petty." Written and narrated by Andrew Couch.LinkVisit the Raised By Whoops Substack Tunes in this EpisodeDelicado -Oscar AlemanRBW Theme - Pale CricketALTR - Enter the CowboyZiggy - Hide and SneakSemo - Silver Lining

In episode 206 of The Raised Rowdy Podcast, Nicky T and Kurt Ozan sit down with Ryan Waters to discuss his new album All I’ve Ever Known. Ryan shares insights into the songwriting process, collaborations with fellow artists, and the transition from releasing EPs to creating a full-length album. They explore the themes and lyricism […]

The Ryan Waters Band is no stranger to small-town life and real country living. Inspired by his roots, Ryan made a splash with “Creek Don't Rise,” quickly driving new fans to social media and sparking a string of viral moments on TikTok. Ryan sat down with Sam to talk about his debut album All I've Ever Known, hunting stories, and the drive to push for the success you want. Learn more about Ryan Waters Band: https://www.officialryanwatersband.com/ Follow Ryan Waters Band on IG: https://www.instagram.com/ryanwatersband/ Follow Outsider: https://www.instagram.com/outsiderig/ Shop Outsider: https://www.outsider.com/   Follow Jay: https://www.instagram.com/ifjayhadinstagram/   Follow Sam: https://www.instagram.com/sammackey615/   Watch on YouTube: https://www.youtube.com/@WeAreOutsider/podcasts This podcast was sponsored by the following: Spartan Forge, use code OUTSIDER20 for 20% off a premium membership.  Code Blue Scents, use code OUTSIDER15 for 15% off your order. Learn more about your ad choices. Visit megaphone.fm/adchoices

HADESTOWN Book, Music, & Lyrics by Anaïs Mitchell | Music by Lucy Simon | Adapted from the novel by Frances Hodgson BurnettWorks Consulted & Reference :Hadestown (Original Libretto) by Anaïs MitchellWorking on A Song: The Lyrics of Hadestown by Anaïs MitchellMusic Credits:"Overture" from Dear World (Original Broadway Cast Recording)  | Music by Jerry Herman | Performed by Dear World Orchestra & Donald Pippin"The Speed Test" from Thoroughly Modern Millie  (Original Broadway Cast Recording) | Music by Jeanine Tesori, Lyrics by Dick Scanlan | Performed by Marc Kudisch, Sutton Foster, Anne L. Nathan & Ensemble"Why God Why" from Miss Saigon: The Definitive Live Recording  (Original Cast Recording  / Deluxe)  | Music by Claude-Michel Schönberg, Lyrics by Alain Boublil & Richard Maltby Jr.  | Performed by Alistair Brammer"Back to Before" from Ragtime: The Musical (Original Broadway Cast Recording)  | Music by Stephen Flaherty, Lyrics by Lynn Ahrens | Performed by Marin Mazzie"Chromolume #7 / Putting It Together" from Sunday in the Park with George (Original Broadway Cast Recording)  | Music & Lyrics by Stephen Sondheim | Performed by Mandy Patinkin, Bernadette Peters, Judith Moore, Cris Groenendaal, Charles Kimbrough, William Parry, Nancy Opel, Robert Westenberg, Dana Ivey, Kurt Knudson, Barbara Bryne"What's Inside" from Waitress (Original Broadway Cast Recording)  | Music & Lyrics by Sara Bareilles | Performed by Jessie Mueller & Ensemble"All I've Ever Known" from  Hadestown (Original Broadway Cast Recording)  | Music & Lyrics by Anaïs Mitchell | Performed by Eva Noblezada, Reeve Carney, Anaïs Mitchell, Hadestown Original Broadway Company"Maria" from The Sound of Music (Original Soundtrack Recording)  | Music by Richard Rodgers, Lyrics by Oscar Hammerstein II | Performed by Evadne Baker, Anna Lee, Portia Nelson, Marni Nixon"My Favorite Things" from The Sound of Music (Original Soundtrack Recording) | Music by Richard Rodgers, Lyrics by Oscar Hammerstein II | Performed by Julie Andrews"Corner of the Sky" from Pippin (New Broadway Cast Recording) | Music & Lyrics by Stephen Schwartz | Performed by Matthew James Thomas“What Comes Next?” from Hamilton (Original Broadway Cast Recording) | Music & Lyrics by Lin-Manuel Miranda | Performed by Jonathan Groff

It's been well known for many decades that exercise provides many benefits to our health. But a new scientific consortium is revealing new insights into just how profound exercise can be for the human body. William Brangham discussed more with Euan Ashley, a professor of cardiovascular medicine and genetics at Stanford University and the newly named chair of its department of medicine. PBS News is supported by - https://www.pbs.org/newshour/about/funders

It's been well known for many decades that exercise provides many benefits to our health. But a new scientific consortium is revealing new insights into just how profound exercise can be for the human body. William Brangham discussed more with Euan Ashley, a professor of cardiovascular medicine and genetics at Stanford University and the newly named chair of its department of medicine. PBS News is supported by - https://www.pbs.org/newshour/about/funders

In this episode, Dr. Ray Self will simplify and clarify how to understand the Bible and your Christian faith. Dr. Ray is talented at making the most important messages easy to grasp. Christianity doesn't have to be complicated, nor does the Bible. The key is to understand what God is trying to communicate to us and the impact it can have on our lives. 2 Tim 2:15  Be diligent to present yourself approved to God as a workman who does not need to be ashamed, accurately handling the word of truth.  Help Dr. Self continue this show - partner at www.icmcollege.org/donate  Answer your call by enrolling with the International College of Ministry at www.icmcollege.org/enroll  Buy Dr. Ray Self's new book "The Call" for a minimum donation of $15 to Cash App $drrayself or www.icmcollege.org/donate Follow and subscribe to Self Talk With Dr. Ray Self at our podcast website  - https://www.icmcollege.org/selftalk.   Click here to purchase Dr. Self's book – Hear His Voice, Be His Voice, or visit Amazon.com. Check out our new store at – www.icmcollege.org/merch  Click here to purchase Dr. Self's book – Redeeming Your Past and Finding Your Promised Land, or visit Amazon.com. Or our new podcast website at https://www.buzzsprout.com/2249804   For show topic suggestions, email Dr. Ray Self at drrayself@gmail.com Enjoy free courses offered by the International College of Ministry Free Courses Show host bio - Dr. Ray Self founded Spirit Wind Ministries Inc. and the International College of Ministry. He holds a Doctorate in Christian Psychology and a Doctorate in Theology. He currently resides in Winter Park, Florida. He is married to Dr. Christie Self and has three sons and a daughter. 

On this episode of the Patriarchy podcast, I give a brief review of the Patriarchy Conference and play one of the talks from the conference. If you missed the conference or wanted to hear it again, check this out. In this talk John Michael Clark talks about becoming the best man your wife and children have ever known. #PatriarchyConference #FamilyLeadership #Headship #Marriage #Responsibility #MensRoles #SpiritualGrowth #Relationships #Masculinity #PersonalDevelopment #MarriageRoles #Attraction #SpiritualLeadership #EmotionalIntelligence #FamilyDynamics #Communication #PersonalGrowthFind Us on Social Media: Gab: ThePatriarchyPodcast Facebook: ThePatriarchyPodcast Twitter: @PatriarchyPod Instagram: @ThePatriarchyPodcast Visit us on all our social media platforms: https://linktr.ee/thepatriarchypodcast Listen on the go on your favorite podcast service: Apple - https://tinyurl.com/f3ruzrsa Spotify - https://tinyurl.com/58tm5zjz Sovereign King Church: https://linktr.ee/sovereignkingchurch Music Credits: "Twisted" & "District Four" by Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 3.0 License Additional music from Pixabay.com Don't forget to like, share, and subscribe for more discussions on faith, theology, and the challenges of modern masculinity!

Stand Up is a daily podcast. I book,host,edit, post and promote new episodes with brilliant guests every day. This show is Ad free and fully supported by listeners like you! Please subscribe now for as little as 5$ and gain access to a community of over 700 awesome, curious, kind, funny, brilliant, generous souls Dr. Deborah Adamy has been committed to her meaningful 38 year career in advocacy,  healing and activism. She has advocated for the rights of the most vulnerable, counseled people from all walks of life, developed curriculum, trained social workers and educators, coordinated research projects, ran groups and facilitated workshops. She cares deeply for humanity and believes we are capable of reducing our daily suffering, finding deeper meaning and purpose in our lives, and living more fully into our potential. Listen to Deborah Podcast   PHILOSOPHY Deborah is a holistic psycho-spiritual therapist, who encourages her clients to live from love rather than fear, be guided by their intuitive inner wisdom, and integrate trust, compassion, and empowerment into their daily lives. When she began her private therapeutic practice over 30 years ago, Deborah was compelled to incorporate a holistic approach, understanding that the integration of body-mind-spirit enriches our health and well-being.  She embodies this belief by caring wisely for her body, mind, and spirit. Deborah values and brings consciousness to nutrition, physical exercise and vitality, a thirst for knowledge and wisdom, and her ever-growing spiritual practices.  EDUCATION Deborah completed her doctorate in clinical psychology from The California Institute of Human Sciences in Encinitas, CA; received her masters degree from Hunter College School of Social Work in NYC; graduated Magna Cum Lade with a BA in Psychology and Teaching Certification in elementary and special education from College of New Rochelle, NY; and earned her LMT at The Swedish Institute of Massage Therapy in NYC, having studied eastern and western massage modalities. She is also an ordained minister in the Universal Life Church. PROFESSIONAL BACKGROUND From high school through the early years following college, Deborah taught modern and jazz dance to children, teens and adults. People would question how she could have two seemingly distinct jobs: dance teacher and social worker. For Deborah there was not such a disconnect, whether teaching dance or teaching communication skills, both helped people believe in themselves and build confidence. Deborah began her social work career in the early 80s empowering minority women to enter the work force with confidence, assertiveness and effective job skills. She worked in school-based drug prevention programs, counseling teenagers and families and later running parenting workshops throughout Brooklyn and Queens, NY.  She was a consultant for numerous organizations providing presentations, trainings, staff development workshops, retreats, clinical case conferences, curriculum development, professional development and strategic planning for counselors, educators, social workers, and policy makers. In addition, Deborah worked at a community-based health center, integrating medical and educational services for the most vulnerable. She was hired by Yale University's Consultation Center to direct innovative, comprehensive programs in high-risk middles schools (healthy decision-making curriculum, peer leadership, peer mediation, parent support groups and community organizing collaboration). Deborah coordinated a federally funded research project through Hunter College School of Social Work (HCSSW), focused on effective child welfare practices. Following that research project, she became the Director of Training at HCSSW's National Resource Center for Permanency Planning, helping to improve policy and practices in child welfare throughout the country. Deborah has developed a thriving private practice in Psychotherapy working with children, teenagers, and adults, individuals, couples and families for over 30 years. Over a decade ago, Deborah did an internship with Hospice, where she discovered her natural comfort with the dying process. That comfort and humility led to being invited into the dying process of friends and relatives. Her first experience of being present as a dear friend passed allowed her to feel like a mid-wife to death. She experienced the sacredness of ushering someone to let go of what they previously anguished over, forgiving others as well as themselves, and releasing fear as the dying person softened into acceptance and peace. She is grateful for the wisdom, compassion and guidance she found in "The Tibetan Book of Living and Dying" for not only sitting at the bedside of the dying, but being inspired to write and deliver meaningful eulogies. As an ordained inter-faith minister, Reverend Dr. Mama A feels honored and privileged to officiate weddings. She marvels at the invitation into the vulnerability, intimacy and dreams of couples, while helping them create sacred ceremonies to profess their love. Rev. Dr. Mama A thoughtfully delivers unique, personally relevant, heartfelt sermons, while delighting in these celebrations of love.   The Stand Up Community Chat is always active with other Stand Up Subscribers on the Discord Platform.   Be sure to visit https://www.patreon.com/PeteDominick/membership and scroll down where you should see a "Connect to Discord" button. You can also look at https://support.patreon.com/hc/en-us/articles/212052266-How-do-I-get-my-Discord-Rewards- for more info. Join the SUPD Marketplace! Watch the video to learn how to post at StandUpWithPeteDominick.com/marketplace Join us Thursday's at 8EST for our Weekly Happy Hour Hangout!  Pete on Threads Pete on Tik Tok Pete on YouTube  Pete on Twitter Pete On Instagram Pete Personal FB page Stand Up with Pete FB page All things Jon Carroll  Follow and Support Pete Coe Buy Ava's Art  Hire DJ Monzyk to build your website or help you with Marketing    

Host Chris Vetrano sits down with rising country artist Alexandra Kay to discuss her incredible accomplishments as an independent artist. Alexandra opens up about the personal challenges she faced during her divorce, which inspired the raw honesty of her debut album "All I've Ever Known." She also shares how she's navigated the music industry, turning down major label deals to maintain creative control. You will be inspired by Alexandra's resilience, self-confidence, and her commitment to connecting with fans through vulnerable, emotionally-driven songwriting. Plus, the singer answers fan questions and offers a unique behind-the-scenes look at the life of an independent artist as she prepares for her fall tour with Jelly Roll. Listen! It's Vetrano: https://listenitsvetrano.com/the-gist-podcast/ Instagram: http://instagram.com/CMVetrano TikTok: http://tiktok.com/CMVetrano YouTube: https://www.youtube.com/@listenitsvetranoFacebook: http://facebook.com/ListenItsVetrano X: http://twitter.com/CMVetrano Hosted on Acast. See acast.com/privacy for more information.

Exercise is a conundrum. On the one hand, physical activity is clearly one of the best interventions for preventing physical disease and mental suffering. On the other hand, scientists don't really understand how it works inside the body or what exactly running, jumping, lifting, and squatting do to our tissues and organs. That's finally changing. Euan Ashley, a professor of genomics and cardiovascular medicine and the chair of the Stanford Department of Medicine, is a member of a new research consortium that studies rats and humans to understand the molecular changes induced by exercise. Today we talk about the earliest findings from this new consortium, how exercise might have disparate effects in men versus women, why nature's most effective cardiovascular intervention also seems to be nature's most effective mental health intervention, as well as whether it will one day be possible to identify the molecular basis of exercise precisely enough to develop exercise pills that give us the benefits of working out without the sweat. If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek Thompson Guest: Euan Ashley Producer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

What a privilege it was to spend this time with Thangam Debbonaire. It's such a shame that she isn't a part of the Labour government however she is now standing to become Chair of the Labour Women's Network (https://www.lwn.org.uk/). I think she'd be a fantastic Chair and I really hope she wins this September.We discuss Reflections on the general electionHow we understand the rise of the Green Party The vital work of the Women's Labour network Narrative of the nation and how to make it progressive and inclusiveHow Labour prepared for government Why Labour is the greatest political movement the world has ever seen Whatever you do, don't keep this show to yourself. Share it with others, this is packed with wisdom, inspiration and humour. Email labourpodcast@gmail.com Twitter: @labourpodcast- Fancy listening to the songs chosen by our Win24 Labour Candidates? Then check out our Spotify Playlist - https://open.spotify.com/playlist/4fejZmjzeSG36fgrxZryTx?si=dfdb82c93ed94fd8

Celebrated Hollywood actor and bestselling memoirist Billy Dee Williams (WHAT HAVE WE HERE?) goes behind the scenes about his friendship with James Baldwin and Baldwin's love (and critique) of Hollywood. Then Baldwin historian Ed Pavlić dives into Baldwin's love of cinema, his love/hate relationship with Hollywood, and his impact on American film culture. This podcast is a production of Penguin Random House Media + Knopf Publishing. It is hosted by Cree Myles, produced by Stephanie Bowen and Shalea Harris, edited by Clayton Gumbert, and executive produced by Trevor Baldwin.For more information and to get the deluxe centenary editions of James Baldwin's works, check out JamesBaldwinBooks.com, JamesBaldwin.info, and All Ways BlackListen to more podcasts from Penguin Random House:THIS IS TASTE, a food culture podcast CRIMINAL TYPES, a podcast featuring your favorite crime fiction authorsMARLON & JAKE READ DEAD PEOPLE, co-hosted by Marlon JamesBOOKS CONNECT US

Recently, a series of papers were published in Nature and Nature journals illuminating the physiologic effects of exercise from an NIH initiative called MoTrPAC. To understand the wealth of new findings, I spoke with Professor Euan Ashley, who, along with Matt Wheeler, heads up the bioinformatics center.Earlier this week, Stanford announced Evan Ashley will be the new Chair of the Department of Medicine. He has done groundbreaking work in human genomics, including rapid whole genome sequencing for critically ill patients and applying the technology for people with unknown diseases. A few years ago he published The Genome Odyssey book. As you'll see from our conversation, he has also done extensive work on the science of exercise.Video snippet from our conversation. Full videos of all Ground Truths podcasts can be seen on YouTube here. The audios are also available on Apple and Spotify.Transcript with audio and external linksEric Topol (00:06):Well, hello, it's Eric Topol with Ground Truths, and I'm really delighted today to welcome my friend, Euan Ashley. He is the Roger and Joelle Burnell Chair of Genomics and Precision Health at Stanford. He's done pioneering work in genomics, but today we're going to talk about something very different, which he also is working in exercise. Exercise the cover of a Nature paper in May regarding this MoTrPAC, which we're going to talk about this big initiative to understand the benefits of exercise. But before I hand it over to Euan, and I just want to mention his description of the paper that he posted to summarize started with, “Exercise may be the single most potent medical intervention ever known.” So Euan welcome.Euan Ashley (01:01):Yeah, well, great. It's wonderful to be here, Eric, and so nice to see you.Eric Topol (01:06):Yeah. Well, we have a lot to talk about because exercise is a fascinating topic. And I guess maybe we'd start with the MoTrPAC, which is an interesting acronym that you all came up with. Maybe tell us a bit about that with the 800 rats and the 2,400 people and the 17,000 molecules, there's a lot there.Euan Ashley (01:24):Right, right. Yeah. Well, first of all, of course, before you do any scientific study, especially with a large number of people in a consortium, you need a good acronym. So that was where we started with the idea was to focus on the molecular transducers of physical activity. As you pointed out there at the beginning, we really don't have a more potent medical intervention, especially for prevention of disease. I mean, it's just such a powerful thing that we have, and yet we don't really understand how it works. And so, the MoTrPAC Consortium was designed to really work together, bring groups of people across the US together who all have some interest in exercise and some ability to measure molecules and really put together the world's largest study of exercise to try and start answering some of the questions about where the potency of this intervention come from.Eric Topol (02:20):So the first crop of papers, and there were several of them that came out all on the same day in Nature publications, was about the rats. The people part is incubating, but can you give us a skinny on, there was a lot there, but maybe you could just summarize what you thought were the main findings.Key MoTrPAC FindingsEuan Ashley (02:43):Yeah, of course, of course. And the MoTrPAC Consortium, I'll say first of all, yeah, large group is probably I think 36 principal investigators funded by the Common Fund. And so, it brings together large numbers of people, some of whom who spend most of their time thinking about let's say animal exercise. Some have spent a lot of time thinking about humans in exercise and many of whom think about measuring technologies. And as you say, these first group of papers were focused on the rat study, but actually the study goes much more broadly than that. But of course, there are some advantages to the animal protocols. We can look at tissue and we'll talk about that in a moment. But the humans, of course, are where we're most interested in the end. And we do have tissues coming from humans blood and adipose tissue and skeletal muscle, but those are obviously the only organs we can really access.(03:31):So there's a rat study, which is this one we'll talk about, and that's aerobic exercise and training. There's human studies that include aerobic exercise, strengths studies as well. There's a study in kids, pediatric study and then also a study of people who are very fit because here we're focusing on the change from sedentary to fit. And so that gives us the key exercise signal. So this first crop of papers was really our first look, cross-tissue, cross multi-omics, so multiple different modalities of measurement. And I think, yeah, we were like about nine and a half thousand assays, 19 tissues, 25 different measurement platforms, and then four training points for these rats. So let's talk about the rats for a minute. What do they do? So they normally live at night. They're active at night. In this study, we reverse that so that we can actually do the studies during the day.(04:25):So we reverse their at night cycle and they do their treadmill exercise over the course of several weeks. They start with about 20 minutes, and they do more every day. There's a control group of rats that just get placed on the treadmill and then don't do any exercise. And so, this is a controlled study as well. And over the course of time, we work more, it's about eight weeks in total and then two days after each of those bouts of exercise. So it's not an acute study, we measure to see where we are. So we also have this time trajectory of exercise. So what did we find? I mean, I think the first thing I would say, we talked about just how potent exercise is. It's very, very clear from looking at all these tissues that when you exercise regularly, you are just a different person, or in this case a different rat.(05:15):Like literally every tissue is changed dramatically and some in quite surprising ways. So I give you a couple of the things that surprised me or that I thought were most interesting. The first thing was this question of how does exercise actually work? Because exercise is a stress. You go out and you pound the pavement or you're on the bike or whatever, and then your body recovers. And so, there's been this idea, it's referred to as hormesis, this idea that some of the benefit of exercise might come from this recurrent stress. So your body learns how to deal with stress. And so given that we were very interested that this heat shock response was so prominent across multiple tissues. So heat shock proteins are molecular chaperones and they take care of protein folding to make sure it's appropriately done and they prevent protein aggregation. And when proteins need degraded because they're damaged, the heat shock system jumps in.(06:10):So perhaps not surprising, but pretty interesting that the heat shock proteins were very prominent part of the stress response to exercise. And remember, this is not acute exercise, so these are benefits that are built up over time, so that was one. A surprising one to me, the adrenal gland. So we're used to thinking of adrenaline as an epinephrine, as a stress hormone, but actually we saw dramatic changes in the adrenal gland and we don't necessarily think too much. You think about the exercising muscles, you think about the heart, we think about the lungs, when we think about exercise, you don't necessarily think that you're changing your adrenal gland, but it was one of the most changed tissues. The immune system was a common upregulated system. We saw that. And in fact, some of the tissues in which the immune genes were most changed were somewhat surprising.(07:02):So the small intestine, for example, was a place where there was a highest enrichment of immune mediated pathways. And then some tissues changed pretty early, like the small intestine changed after just one or two weeks of training other tissues like the brown adipose tissue. It was more like seven or eight weeks of training before we saw the real changes in there. So just one or two little things that struck out, but I think this really the first molecular map of exercise. So we're looking across the whole system across multiple modalities of measurement across multiple tissues.Simulating StressEric Topol (07:34):So as far as understanding the benefits of exercise, does this tell us that it really does simulate stress that it's conditioning the body to deal with stress as reflected by the various points you just summarized?Euan Ashley (07:51):Yeah, I think that is exactly right. I mean, part of what we were trying to understand was in what way are you changed after you do exercise regularly? And I think if we think about things that are positive, then the ability to deal with stress at a cellular level, quite literally repair mechanisms seems to be a big part of it. The other aspect that was interesting is that when you're measuring this many analytes, you can also compare that with disease. And so, we understand that exercises is preventive benefit against disease. So in some cases, and this was work highlighted by my colleague Maléne Lindholm in the mitochondrial paper that came along with the main paper and she looked with a team across all mitochondrial changes across all of the tissues of the cell. So these are the workhorses of the individual cells that like the batteries inside the cells of the mitochondria.(08:54):And we saw big changes across, it's not surprisingly, but it's the energy source for cells, big changes across many tissues. But interestingly for two specific really important diseases, a liver disease in one case and type 2 diabetes on the other, it was very clear that the training upregulated a network that was exactly the opposite of that of the disease. And so, it really was intervening in a way that was very specifically opposite to the way we know disease mechanisms go. So it does seem like, I mean people talk about an exercise pill. I think this shows that that is just not going to be possible. There may be ways we could mimic some elements of exercise, but there's no pill. This is a multisystem, multi-tissue, multidimensional response to exercise.Eric Topol (09:44):Yeah, I think it's really important. That was one of the questions I was going to ask you is whether this would ever be simulated by a drug. And I think you already answered that, and the fact that it's so comprehensively sweeping across every organ and all these different signals, tens thousand plus signals across them, it's really striking. We never really understood the benefits of exercise and not that it's all resolved by any means. Some of the things that were interesting too was the sex specific findings. Maybe you want to comment about that because we don't spend enough time thinking about how sex does have a big effect on physiology.Sex-Specific FindingsEuan Ashley (10:24):Yeah, I mean that's a really good point and one that I think was really underlined for us at every corner, every turn of the analysis here. So really no matter which measurement modality, no matter which tissue, no matter which point of training, if we just asked these computer models to sort of separate the data according to the prominent signals without giving it a clue of what to do, the so-called unsupervised models, then sex basically came out every single time. So I think you say you're absolutely right that we so often overlook the difference. For years we've said, oh, it's too expensive to do animal studies in both sexes, so we'll just pick one. And males were picked more often. But there are plenty of studies that were just females, and I mean that clearly is wrong, and we are really, sometimes it appeared like we're almost dealing with two different species.(11:18):They were so different. But I think we can also learn from what those differences were. Interestingly, some of them were most profound in adipose tissue, so in fat, and that was the case both at rest, sedentary and amplified by exercise. So we saw big difference between females and males in relation to the kinds of signals that were prominent in the white adipose tissue. So this fat storage tissue, for example, in sedentary females, insulin signaling and the trigger to make fat and store fat was very prominent. But whereas in the males, even before any exercise, the fat signals were more related to metabolism, and we could have wild speculation about in evolutionary terms why that might be. Obviously, males and females have different biological many differences in their biology and obviously thinking about hormone systems and specifically pregnancy of course. And so, we could probably come up with some theories. In reality, all we know now are these observations were found and they're pretty interesting and they show us that we really always need to think separately about both sexes and look at both independently.Eric Topol (12:39):Well, and the other thing that you already pointed out, but I just want to underscore, you can't do this stuff in people. You can't just do fat biopsies and whatnot. So I mean, the fact that you can do this multi-omic, multi-organ type assessment is just really an extraordinary opportunity for learning. And while we're on the white fat story just briefly, we would rather have a lot more brown fat, but as we age, and I assume it's the same in rats, they don't have much as they get older brown fat. Does exercise help us get more brown fat or are we just stuck with the white adipose tissue?Brown vs White FatEuan Ashley (13:21):Yeah, well, it certainly allows us to have less of a white adipose tissue, and I think it's potential that our brown adipose tissue maybe more functional, and for those who are listening who are not familiar, I mean these really are different colors that relate to the actual color of the tissue, but the color is different because the brown adipose tissue contains lots of mitochondria and lipid droplets, and the brown adipose is there to help essentially generate heat. It has a very different function in a way, but even white adipose tissue that we think of as just being about storing energy, people think of fat as a very metabolically neutral or inert tissue, but in reality it's not. It's signaling. It's constantly, it's a tissue that's as alive as any other and not just a storage for excess energy, but exercise definitely appears to alter both in this sexually dimorphic way as we noted already and clearly both in a positive health way where I think the makeup of the brown tissue is different. The white tissue, there is less of it obviously with exercise, which is something that is well known, but not new here for the first time. But still important to have seen that even in the rats.Eric Topol (14:49):And there's even, we talked a moment go about drugs, but there are some molecules that are thought to be able to help convert white to brown fat that are understudy and we'll see if they get anywhere that's interesting. But also, you talked about aerobic exercise and with us both being cardiologists, and I know throughout my earlier part of my career, we only talked about aerobic exercise. There was no such thing as strength training, and we even discouraged that or we never talked about it. Now we know how important strength training is and not just strength and resistance training, but balance and posture and all these other things. I assume you can't study that in the rats.Euan Ashley (15:32):Well, it's not impossible. This study of course is about endurance, but as you say, and there are some models, I mean I've even seen models in trying to trigger flies to do strength training.Eric Topol (15:46):Wow, I didn't know that.Intensity of ExerciseEuan Ashley (15:46):That somewhere, yeah, we'll have something, there are various methods of making animals hang off things, and this was treadmill. So it's a fairly routine and standard I think part of a rat's life to run. So this was not so different. As we mentioned at the beginning in the human study, we do have a strength portion and the endurance portion, which I think is very important because as you say, the benefits of exercise are found really across both of those. And indeed, as you say, flexibility and other often neglected element of physical activity. But yeah, those benefits are there for both aerobic exercise and endurance. And in fact, they are perhaps even higher for higher intensity exercise. Although I think we don't necessarily recommend everybody do higher intensity exercise. I don't think it's necessary to get most of the benefits of exercise, but there is some additional benefit.(16:42):One of my favorite facts, I think I first saw it probably on a presentation a few years ago, but I looked up the original and recalculated it. But if you look at this very big study of half a million people and look at their physical activity over the course of years and correlate it with their likelihood of being alive or being dead, then it was clear that one minute of exercise bought you five minutes of extra life. And I just thought that was just a really interesting way of putting it essentially. And actually it's a little more, if you did high intensity exercise, one minute would give you seven or eight minutes of extra life. So I tell this to my patients when they come in and tell me they don't have enough time to exercise. I said, oh, well, one minute of exercise. I'm not very popular when I tell them that, but anyway.Eric Topol (17:30):You think it's true. Do you think it's based on good data?Euan Ashley (17:34):Well, the data is large, I mean half a million people. I think we've also seen it currently since the early fifties when we were first doing the London bus conductor study that Jerry Morris did that you will know well, where he compared bus conductors on the London to the bus drivers and found a significantly reduced cardiovascular mortality among the conductors because they were on their feet all day up and down stairs and the driver otherwise in the same environment the drivers were sitting. So I think we have a wealth of epidemiologic correlative evidence that exercise leads to a greater length of life, greater longevity, maybe more than for anything else. The causal evidence is less of course, but we do have causal evidence too. There are enough randomized trials and now increasingly some genetic causal evidence that helps us understand that this is really a causal link and that we actually can change our outcome if we do additional exercise.Mental Health BenefitEric Topol (18:32):Oh, and I don't question at all what you said about the enhancing healthy aging health span and even possibly lifespan. I just wondered about the one to five ratio if we could assert that. I mean that's really interesting and it's a good motivating factor because as you well know by that WHO criteria, one out of four people aren't even close to the modest exercise recommendation. So we got ways to go to get people to spruce up exercise. Now speaking of people, I do want to come back to MoTrPAC and the people plan, but I do want to before that get your sense about a couple of really fascinating studies. So earlier this year there was a study of every exercise study that's been looking at mental health along with SSRIs that name drugs that are used for mental health. And it was a pretty fascinating study. I think I'm just going to pull it up. They looked at everything that this is for depression, walking, jogging, yoga, strength training, SSRIs. And what was fascinating is that dancing, walking, jogging, it made the drugs look like a joke. They didn't seem to work at all. So this was 218 studies with over 14,000 people. And so, I don't know that enough people recognize this fact that this Prozac nation and all this stuff about the SSRIs, but exercise seems to do wonders for people who are depressed, anxious, stressed. What do you think about that?Euan Ashley (20:26):Yeah, I mean it's exactly right. I mean I think that it's very clear from the data and as you mentioned, you and I tend to focus first on the cardiovascular benefit, which is very significant, potentially 50% reduction in risk, but there are similar sorts of numbers when you look at mental health and exercise as an intervention for mental health has been very well studied and has these really dramatic benefits. And I think even if we go in the more general population and think about the fact people talk about a runner's high or an exercise high, and many, many of us, myself included, feel that. And a few years ago, I started exercising every morning and now if I don't do that, I really feel like I'm missing something, there's something in the chemistry of my brain is not quite right. And so, I think that benefit for those who have mental health issues is also very much felt and is real at the brain chemical signaling level and with this few adverse effects as exercise has, I do think we need to think of it earlier and more prominently for almost every disease.Eric Topol (21:40):Yeah, you're I think alluding to the opioids that are released with exercise and addiction to exercise, which is what ideally if everybody could be addicted to exercise, that might help a lot of things. As you mentioned in your post that I started with, “its benefits in prevention outstrip any known drugs: 50% reduction in the cardiovascular disease, 50% reduction in risk of many cancers, positive effects on mental health that we just discussed, pulmonary health, GI health, bone health, muscle function. You name it.” So you said it really well there, and that was just one recent report that substantiated the mental health. I want to also mention another report that's fascinating on cancer that is a publication again recently was looking at both mice and people with pancreatic cancer. And what was fascinating about it is the more exercise of the mice and in the people, the more survival that is from pancreatic cancer, which as we both know and all the listeners will know, is that one of the worst cancers of humankind. So the affecting cancer is fascinating. Now can you dial up your immune system response with exercise?Euan Ashley (23:02):Yeah, I think you can. And I think we were at some level expecting to see it because it's certainly a known thing, but I think again, this is able, our ability to measure it in this study is just much deeper than we've ever had in any study before. And so, I think when we think about mechanisms that might relate to reduced risk of cancer, as you say, we think first of the immune system and that signal was there in many places. As we mentioned at the very beginning, sometimes to me in some slightly surprising places like the small intestine, we don't think of that necessarily as the seat of immune activation, but I think what we were doing, what we were seeing is those signals really across all the tissues and ultimately the immune system is a distributed system. It senses in multiple places and then obviously has implementation.(23:53):Now exactly in what way we've turned up our T or B cells, for example, to be able to attack those cancers or support the therapy that's been given. I don't think we understand that yet. But actually, you bring up another great point, which is part of MoTrPAC was to create this molecular map and analyze it and put the first analysis out there. So that's what we've done, but just as big and maybe even a bigger reason is that to release the data and to make it accessible for everyone and anyone in the world as of the moment this paper came out can go to our data portal at https://motrpac-data.org/ and download the data and then use that in their own work. They can do their own analysis just of this data, but also what we're hoping is that they'll start to use the data, let's say as control data for a cancer study or for a diabetes study or for others. So we really hope it'll fuel many, many more studies over many years from now.Eric Topol (24:52):Yeah, I mean that open science approach to applaud that it's so vital and amplifies what's good to come out of this really important initiative. Now you mentioned the opioids and proteins that are secreted with exercise, exerkines is a term that's used and also I guess these extracellular vesicles (EVs) not electric vehicles. Can you tell us about exerkines and EVs and are they part of the story?Euan Ashley (25:25):Yeah, and actually in the human study there's a specific exosome analysis that will be reported there. Yeah, I think that when we think about this multi-system nature of exercise, and one of the fascinating things was to be able to have these omics in multiple tissues and think about how those tissues were signaling to each other. So obviously there are some tissues that are more fundamental to the exercise response. We think of those as the skeletal muscles. They literally the effectors of our ability to exercise. And I think we think of the heart and lungs in particular in the blood system of course, but we were seeing changes everywhere and it's one of the reasons we were seeing changes everywhere is that there are molecules that are essentially secreted into the circulation or locally by these exercising muscles, exerkines that have a number of positive benefits.(26:21):And it is possible if there's some mechanism towards mimicking some of what exercise does with a drug, then that's a good place to go look for it. And I think that this will also fuel those thoughts. I think we both, we'd agree that there isn't going to be one pill that will do all the magic of exercise, but I think there are probably things we will learn from the study where we say, well, this was a very positive benefit and it seems to be mediated by this particular molecule, and that's something that could potentially lead towards a more targeted drug. I think we'll definitely get into that and understanding just we're systems people are, again, I think we think in physiology, so when we see the tissues like connecting and communicating with each other, I think that just makes a lot of sense from a systems perspective.Eric Topol (27:10):Now getting onto the forthcoming work that's going to come out with the 2,400 people and the different groups that you mentioned, I wonder if it'll include things like biologic aging with DNA methylation, will it have immunomes to characterize the differences in the immune system? What kind of things might we expect? Obviously, you can't get tissue, but for blood samples and things like DNA methylation, can we get some more illumination on what's going on?Euan Ashley (27:41):Yeah, I think we can. And of course, ultimately the human is the organism we're most interested in. Interestingly, I'll say interestingly as well, we can get some tissue and huge credit to both the investigators who are doing this and most credit of all to the individuals who agreed to join the study because they actually agreed not just to give blood samples, but actually to give skeletal muscle samples. So a biopsy of the skeletal muscle and a biopsy of the fat pad. So we will actually have two other tissues in the humans, not this obviously vast range that we talked about with the rat study, but we'll have those two other tissues and we'll also then have the rat data, which is the other great thing. So we'll have this foundational insight that we can then bring to the human study with the humans as we mentioned before as well, we'll have not just endurance but strength trained, we'll have it in kids as well, and we'll have these higher intensity exercise.(28:36):I think we will be able to connect with this, as you mentioned, longevity literature or the health span literature where we can start to think about DNA methylation. We do have genomes of course, on all of the individuals. It won't be a study powered because it's thousands individuals, these kinds of numbers. It won't be powered to give us genetic predictors. If you think about the studies had to be hundreds of thousands of people and even more now in order to give us, let's say common variant predictive. So we won't be able to do that, but there's lots of connections we'll be able to make by being much closer to the effector systems, which is to say the proteins and the metabolites and those signals we're already seeing are very significant. And so, I do think that there'll be a lot of new signals that we'll see that are specific to humans that will connect into other bodies of work, for example, the longevity, and we'll see those in blood and I hope that we'll be able to connect also the skeletal and adipose tissue data as well.Eric Topol (29:37):One of the things that would be wonderful to connect if you can, our mutual friend and your colleague at Stanford, Tony Wyss-Coray has these organ clocks that have been validated now in the UK Biobank, and then you can see what's happening with the wealth of plasma proteins that have been validated across each organ. So without having to do tissue, you might get some real insights about organ clock. So I mean, I'm really looking forward to the people part of this. When do you think the next wave of output's going to come from MoTrPAC?Euan Ashley (30:11):Well, I think that another element of the study is that we have ancillary studies, so investigators who said, I want to be able to use MoTrPAC data and use some of the infrastructure, but I'm looking for funding for my parallel study. So some of those ancillary studies will start to come out over time, which I think will be interesting and will be a very good place to see the breadth of activity that has been triggered by this one investment. The human study is coming along. We're actually just now plotting the last two or three years of the consortium. Time has really gone by pretty fast, and we've had to scale back just a little bit on the total numbers of humans, but it should still be, I think probably the largest multi-omics study of humans that there has been. And I think if we were going to plan one of those, then planning it to study around exercise definitely, definitely makes sense. So there is some data that was, of course Covid happened in the middle of this, so that was a major challenge with hitting the original numbers. But there's some data from the humans who were recruited before Covid hit that will be coming out and hopefully in the relatively near future. And then the big study may still be a year or two away to get it finished. But after that, as we say, we hope that the data and the science will continue for I hope decades beyond just the collection of this repository.Eric Topol (31:41):That's great. You mentioned Covid and I did want to ask you about the folks with Long Covid who are suffering from fatigue and exercise intolerance and what do you think about this kind of vicious cycle? Because if they could exercise, it could help them get into a better state, but because of not being able to, it's just a negative feedback loop. Any thoughts about that?Exercise and the Immune SystemEuan Ashley (32:13):I mean, it's such a good point and it's one of course that we talk to many of our patients where they, for whatever reason, sometimes it's because they are struggling with weight or they're struggling with other mobility challenges, and now we have this very large population who are struggling with fatigue. As you mentioned, it's a group that we were somewhat familiar with because of flu and because EBV and other, I mean long syndromes were something we were familiar with. They were just kind of rare, and so there wasn't really much work done on trying to understand them. Now as you've, I think articulated better than anyone, we have this entire population of people because of the scale of Covid who have these symptoms that are recognizable for the first time and including on your podcast, you have had folks on that have discussed it. Some of the insights that have happened from actually applying science, I wish there was an answer that was buried here in MoTrPAC and maybe there is, there will certainly have data from before and after the pandemic and maybe there may be some insights that we can bring to that.(33:20):I certainly think we have a lot of insights on the interaction between infection and the immune system. We talked about the potential for the immune system to be ramped up in that potentially being one of the mechanisms through which this might help cancer. There's also the idea of, and we've seen this with the effect of vaccination on Long Covid, which perhaps surprisingly does seem to have a significant benefit for at least a group of people. The assumption there is that we're ramping up the immune system and it's having that extra effect on whether it's actually pools of hidden antigens that are hidden from the immune system or whether it's some other element of the kind of ensemble attack of the immune system that is related to the symptoms. But either way, I think we feel that having a more ramped up immune system is likely to be beneficial, but at a very real human level, the point you made is the hard one. If you're really fatigued and you just feel you can't exercise, then these benefits are just out of reach and you're in this negative feedback cycle and breaking that cycle is hard. I think we try to suggest people do it very gradually because you can get a lot of benefit from just a little exercise and that's something, so that's some way, and then hopefully people can build up slowly over time, but it's a really big challenge.Eric Topol (34:43):I hope we can crack the case on that because I know that's something holding these folks back and there's just millions of them out there. Now let's talk about the healthy folks that you see in clinic. What do you advise them about exercise besides the fact that one minute we'll give them five minutes, but do you advise them to have X amount of aerobic and X amount of resistance and in the general person, what would you tell them patients?Euan Ashley (35:13):Yeah, yeah, I do. So I suggest habit is everything. So I suggest to people that they exercise every day or take one day of rest because I think there is some benefit with the stress response and having a rest day. So I suggest five or six days a week if possible, trying to get into a habit of doing it. So pick a time that works for you. It could be first thing in the morning, could be last thing at night. The jury's out on when the best time to exercise is. What it's very, very clear is that getting the exercise done is what counts. Accumulating time is also what counts. I mean, if you're not someone who wants to pull on running kit and go out running, that's fine, but accumulating steps, accumulating physical activity and moving is key. So not having people overshoot being too ambitious, but if they're really motivated to do something, then I would say five or six times a week a combination of both aerobic and endurance exercise and strength.(36:07):Usually I suggest two to one in favor of aerobic exercise, but it's also possible I think to alternate and do more 50/50. I think the key is that both are featured and then I think a bit neglected because to be honest, our data on it is just not as good, but flexibility is really critical and particularly in the senior population and for a group who sit all day long, I think for those two groups in particular, flexibility is really under-recognized as a major component. Even in my cardiology clinic, I've helped several patients just get over their back pain by teaching them some back stretching exercises. And so, I think that's neglected. So I suggest all three of those and really it's whatever works for the individual. I think the key is to find, it might be working in a group format, it might be going to a gym, it might just be taking regular walks. The key is to get moving and not sit. Get moving and do it regularly and get into the habit.Individualized Exercise?Eric Topol (37:09):Yeah, and actually on that point about potential individualization in the future, I noticed that you and some people that worked in your lab and others, Svexa is a company you started for exercise. Can you tell us about that?Euan Ashley (37:26):Yeah, this was a PhD student who was in my lab many years ago and was doing his PhD joint between the Karolinska Institute in Sweden. And of course, the country of Sweden has a long history of exercise physiology, science, and as he came out, we realized that there was the potential for optimization of training for individuals, whether they're recreational athletes or elite athletes in the Olympics. And he was interested in taking this and running with it, which he did. So the company originally Silicon Valley exercise analytics, but shortened now to Svexa builds, builds products to help people basically individualize their training. And we work, say with recreational athletes on an individual basis, we work with a lot of Olympic athletes in multiple countries and the technology building the sort of magic sauce that many of these coaches even up to and including Olympic coaches have into a format that can be spread and amplified to many more people is one of the themes.(38:29):And when we think about professional athletes and the company works with a number of well-known brand name teams that are in soccer leagues and in national football league here in the US and really across professional sport, what we're thinking of there is optimizing performance. Of course, all the teams want to win, but reducing injury is the other key part because the management of load, these are professional athletes, they're getting up every day in training and they're trying to optimize their training and their coaches are trying to do that. And it's been a fairly data free zone over the years, but meanwhile, we actually have learned a lot about how to measure individuals and how to measure what training works, and if you think about a team that might be paying 20 million a year for their star player, if that player gets injured, that's a pretty expensive thing. And so, investing a little bit in understanding the training load, helping the coaches understand the data, and then adapting that to each individual in the team so that their chance of injury is lower. That's really a lot of what the company spends its time thinking about.Eric Topol (39:36):Now, do you use sensors like lactate and glucose and AI of their body and how do you figure this stuff out?Euan Ashley (39:45):Yeah, all of that is possible. It's interesting, some sports have a kind of culture of measurement. For example, lactate measurements, which as your listeners will know, is it requires a small blood sample usually from the finger or from the ear lobe. Some sports like swimming have done that for years. But other sports, it's just not been so much in the culture. So I would say that from the company perspective, we work with whatever data is available and we'll make recommendations if people want to think about wearable devices. Of course, the digital era is around us, and you can get a lot from just a standard watch in terms of heart rate, heart rate variability in terms of accelerometry and movement. You can do a lot with just that, but there's lots more. Many of these teams have GPS signals so they know how far an athlete moves in a given game, how fast they move, how much time they spend at tool speed versus medium speed.(40:37):So we can use all of that. And as you say, yes, AI for sure is a large part of what we do and a couple of different ways actually. One is just for the analysis of the data, but another is this idea of scaling expertise. This is something in the AI community. I know you talked about a lot where you could take the expertise of let's say a physician with a very specialized practice or an Olympic coach for a marathon runner and basically make a language model that contains that expertise and then allow many people, thousands of people potentially to benefit from that expertise that we'd otherwise be sort of locked up with next available appointment is 18 months down the road, but if your AI can potentially reflect a lot of what you have, a lot of your expertise, not all of it, we hope, but probably a lot of it, then that expertise could potentially be offered much more broadly. And if it's to help people exercise more and more effectively, it's going to be a lot of good that I think can come from that.Eric Topol (41:33):Yeah. No, it's really interesting. I think there's unlimited opportunities there. It's like Moneyball to the 10th power. It's like all this data that's in sports that gets me, I guess to the last question I had for you, and that is the elite athlete or athlete hard. These are people that are working out endurance just to the max, these extremists, and they're prone to heart issues like atrial fibrillation. Why is that? What's going on with these people that they exercise too much? Is it just the lack of moderation, extremism or what's going on?Euan Ashley (42:10):Yeah, well, so it's interesting that of course you mentioned atrial fibrillation. I think that really is the only downside of exercise, even fairly extreme exercise that I've ever been, I think that we've ever had really good data for. And I would say that over the years, and I've been one way or another touching the exercise science world for 20 years and more now and certainly have been asked very often, surely these people are doing themselves harm. And the reality is, although every now and again there's a study that shows some harm or they measure troponin, they measure something in the blood and someone says, oh, they must be doing themselves harm. It's been very hard to find it. The reality is atrial fibrillation though really is, especially for those ultra endurance athletes, that's for real. And that is, we don't know that it's associated with a mortality impact necessarily, but it's definitely annoying and it slows down.Endurance Athletes and Atrial Fibrillation(43:03):We have athletes who come in and say they're cycling up a hill and suddenly they drop their power drops and they realize they've gone into atrial fibrillation. I used to play basketball with someone who would go into atrial fibrillation, so I would know when to try and get past him once he went into atrial fibrillation. But that's a real thing, and I think one of your questions was why I think I have a lot of close friends who are ultra endurance runners. They're among some of the most chilled and happiest people I know. I think those benefits of exercise are what they're enjoying, and I think there's a literature on addiction to exercise. So there is a small number of people who get addicted to that feeling and addicted to the chemical matter in their brain and can't stop, and they really do get to the point of doing themselves harm.(43:53):Fortunately, I think that's a pretty small number. And overall, although there are many consequences of chronic long-term exercise, almost all of them seem to be positive. The other one that you and I are probably very familiar with is the calcium scans that we see now much more often, it's common for people who've exercised a lot to have more calcium in their hearts. Now they have a lower risk of that. They have lower risk of heart attacks in general, one or two studies muddied the waters just a little. But in general, it's very clear they have very positive health benefits and yet they have more calcium. So they are an exception. We've seen in our sports cardiology clinic here at Stanford, several athletes every month, several will come in with this finding and we are explaining to them, this doesn't mean they have the same risk as someone who hasn't exercised at that level who would have that calcium score. It does seem to be very different, and it may be that there's a stabilization of those plaques in the arteries. I don't think we understand the biology that well, but we understand the epidemiology quite well, which is that their risk really is still low.Eric Topol (44:59):Yeah, no, it's interesting that there's still some uncertainties there and MoTrPAC may help guide us or at elucidate some of them. I guess it does bring up one other thing I got to get to with you because we didn't really get to the question of moderate to higher intensity, not to the level of the ultra exercises, but if you just do steps or do you sweat like hell, where do you draw the line? Or is that really part a function of age and ability? When you recommend exercise, because obviously you're rational and there's others out there that are exercising three or four hours a day and they're going to extreme craziness, but just in a reasonable thing, do you think just telling people who are 70 that walking is good enough or do you try to encourage them to push it?Euan Ashley (45:59):Yeah, I do encourage people to push it a bit because I think there's clear evidence that higher intensity, some degree of higher intensity exercise really does provide more benefit. But I think my main message first is because for most people, the potential of moderate versus high is in the distance and in the future for most people, we need to get them off the couch and get them on their feet. So my emphasis is that you can go a long way with just a little movement, even a little standing. And then I think if they're really getting into the habit and really doing some exercise then, and if they don't have a prior history of let's say, heart attack or other medical issues that might make high intensity exercise risky, if they don't have those, then I absolutely do get to the point where I recommend some amount of higher intensity exercise, because I think there is some evidence that it has a little extra benefit.Eric Topol (46:51):Oh, that's great. Well, this is the most in-depth conversation I've ever had with anybody on exercise, so Euan I really appreciate it. I mean, I knew you from all your work in genomics of course, and we've had some overlap from time to time, but the exercise stuff is fantastic. Did I miss anything?Euan Ashley (47:09):No, I don't think so. Just underline again to anyone who's listening if they're interested to play with this data, it's very much out there. It's a tool for the world, and they can go to https://motrpac-data.org/ and even you can do some analysis without downloading any data either. If you just have a favorite gene or a favorite protein, you can type that in and take a look at some of the tools we have there. But yeah, really appreciate the conversation and very fun to chat about what has been a really, really fun project.Eric Topol (47:39):Well, thank you and all the folks at MoTrPAC, all the hard work and of course the funding that got it going to give it that runway of several years. So we'll look forward to more. I hope to convene with you again when some of the other studies come out, and thanks so much.*****************************************************Thanks for listening, reading or watching!The Ground Truths newsletters and podcasts are all free, open-access, without ads.Please share this post/podcast with your friends and network if you found it informativeVoluntary paid subscriptions all go to support Scripps Research. Many thanks for that—they greatly helped fund our summer internship programs for 2023 and 2024.Thanks to my producer Jessica Nguyen and Sinjun Balabanoff for audio and video support at Scripps Research.Note: you can select preferences to receive emails about newsletters, podcasts, or all I don't want to bother you with an email for content that you're not interested in. Get full access to Ground Truths at erictopol.substack.com/subscribe

In this podcast episode, Sandy and Tricia engage in a lively and humorous conversation covering a wide range of topics. They discuss favorite meals, with Tricia favoring Sandy's chicken stir fry, and classic TV game shows, expressing a preference for "Wheel of Fortune." The discussion also delves into personal experiences, including Tricia's revelation of knowing someone involved in a complicated relationship as a side chick. The episode captures their dynamic banter and candid nature, making it an entertaining and relatable listen for the audience.   Revealing a Secret (00:02:47) Tricia's admission of knowing someone who was a side chick and her decision to keep it a secret. Saharan Dust Plume (00:05:05) Discussion about the arrival of Saharan dust in central Texas and its effects on health. Personal Preferences (00:06:46) Sandy's appreciation for her neighbor's cooking and the celebration of her birthday weekend. Track Meet and Buc-ee's (00:07:40) Conversation about attending a regional track meet and a stop at Buc-ee's, including a discussion about their chopped beef sandwiches. New Five Hour Energy Product (00:12:08) Introduction of a new caffeinated barbecue sauce by Five Hour Energy. Turn-Ons (00:13:07) Survey results revealing that cleanliness is a turn-on for 69% of Americans, as discussed by Bill Maher. Dating Tips (00:14:05) Bill Maher's dating tips, including grooming and the importance of hygiene. --- Send in a voice message: https://podcasters.spotify.com/pod/show/sandy-show1/message Support this podcast: https://podcasters.spotify.com/pod/show/sandy-show1/support

Cenk uighur it's great! Did you know he's running for president? Me too we both think Joe Biden should step down! Why didn't AOC or any of the other Democrats ever called for perjury traitor green to be censured and removed from Congress?????? Why haven't the Democrats called for 200 GOP insurrectionists to be expelled???? FN COWARDS

2024-05-26 Morning Sermon

Content warning: mental illness, animal abuse, animal cruelty, violence, domestic violence, and murder. As shared in Part 1 of his story, Eric Johnson is a security professional, author, co-victim of murder, and victim advocate from Michigan. He launched himself towards a career designed to protect and serve the safety of consumers at a very young age. However, his career in victim advocacy would begin after losing his father Bill and Bill's beloved dog to domestic violence in 2021. What came next in terms of the legal system and in terms of his healing is a testament to Eric's strength and fortitude, and the Broken cycle Media team is immensely grateful he was willing to share his time and perspective with us this week. This episode is dedicated in loving memory of Bill Johnson. Eric's Linktree: https://linktr.ee/ericjauthor Eric's Book, My Father's Story: The Murder of the Best Man I've Ever Known: https://amzn.to/3K4z26P Eric's Instagram: https://www.instagram.com/ericjauthor1 Mark Manson's Author Page: https://www.amazon.com/stores/Mark-Manson/author/B00BIJOMOC For a list of related non-profit organizations & resources, please visit http://www.somethingwaswrong.com/resources Thank you again to Miracle Made for sponsoring this episode. Don't forget to upgrade your sleep with Miracle Made. Go to try miracle.com/wcn and use the code 'WCN' to claim your free three piece towel set and save over 40%. Again, that's TryMiracle.com/WCN to treat yourself!

Content warning: mental illness, animal abuse, animal cruelty, violence, domestic violence, and murder. Eric Johnson is a security professional, author, co-victim of murder, and victim advocate from Michigan. He launched himself towards a career designed to protect and serve the safety of consumers at a very young age. However, his career in victim advocacy would begin after losing his father to domestic violence in 2021. What came next in terms of the legal system and in terms of his healing is a testament to Eric's immense strength and fortitude, and the Broken cycle Media team is immensely grateful he was willing to share his time and perspective with us this week. This episode is dedicated in loving memory of Bill Johnson. Eric's Linktree: https://linktr.ee/ericjauthor Eric's Book, My Father's Story: The Murder of the Best Man I've Ever Known: https://amzn.to/3K4z26P For a list of related non-profit organizations & resources, please visit http://www.somethingwaswrong.com/resources Thank you again to Detective Perspective podcast and to Babbel for sponsoring this episode. Don't forget to subscribe to Detective Perspective Podcast and listen every Monday on podcasting platforms and Tuesday on YouTube! Also, don't forget about our special limited time Babbel deal for our listeners. Right now, you can get 55% off your subscription - but only for our listeners - at babbel.com/WCN (rules and restrictions may apply).

TSN's James Duthie joins the program to share some memories of his late friend and colleague Darren Dutchyshen.

This week is an off week as we sit between China & Miami.However, we have a great episode as there was a huge amount of news to dissect not least the story about Adrian Newey looking to leave Red Bull!We also preview the race in Miami which will actually be at a time that will allow Sap to tune in and watch live.The running order of this episode is:1) News & Social2) Brian's Video Vaulthttps://www.youtube.com/watch?v=BWw-80RI4vw. 'He Must Be The Worst Liar I've Ever Known!' | Box Of BLUFFS! | Daniel Ricciardo & Alex Albon. Formula 1 channel. https://www.youtube.com/watch?v=rrVESbOpzRo. Down Under with Oscar Piastri and the Great Barrier Reef Foundation. McLaren channel proper. https://www.youtube.com/watch?v=R53B3eSxxBg. 'I'm Gonna Be Much Better At This Than The F1 Stuff!'

Boris Nayfeld's life is like something out of a movie; orphaned in the former Soviet Union, he served time in a brutal penal colony before establishing himself as a top tier street criminal before escaping for America. No stranger to violence, he got involved in the burgeoning Russian mafia factions rising up in Brooklyn's Brighton Beach during the 1980's. But he's way more than just a two bit gangster. He's been involved in organized crime from Odessa to Thailand to Antwerp, survived 5 assassination attempts, done prison in the US and the former soviet union, and been involved in diamond heists, heroin trafficking, extortion, shootouts, tangled with Russian Thieves in Law…the guy's name carries weight. And somehow, through it all, he survived when nearly everyone else he came up with didn't. Learn more about your ad choices. Visit megaphone.fm/adchoices

End time prophetic Messengers 144k --- Send in a voice message: https://podcasters.spotify.com/pod/show/aei-leon/message

On this week's episode of Artist Friendly, Joel Madden is joined by country singer-songwriter Alexandra Kay. Kay is a viral country star who's shared stages with Tim McGraw, Clay Walker, and Tracy Lawrence, all before releasing her debut album. That project, All I've Ever Known, was shared last October, chronicling her divorce in tender detail. “This album is the most raw, vulnerable, and wide open I have ever been when creating music, which can be terrifying and healing at the same time,” she said in a press statement. Later this year, Kay will go on tour with Jelly Roll, and the run launches in late August. You can grab tickets here. Listen to their conversation on Artist Friendly wherever you listen to podcasts. You can also watch the episode over at Veeps.  ------- Host: Joel Madden, @joelmadden Executive Producers: Joel Madden, Benji Madden, Jillian King Producers: Josh Madden, Joey Simmrin, Janice Leary Visual Producer/Editor: Ryan Schaefer Audio Producer/Composer: Nick Gray Music/Theme Composer: Nick Gray Cover Art/Design: Ryan Schaefer Additional Contributors: Anna Zanes, Neville Hardman Learn more about your ad choices. Visit megaphone.fm/adchoices

Eric Johnson is the author of the bestselling book, "My Father's Story: The Murder of the Best Man I've Ever Known." Eric delves into the life and tragic death of his father, Bill Johnson, who was brutally murdered by his ex-girlfriend in his home, taking not only his life but also that of his beloved dog. Eric shares behind the scenes of the court case and the one thing he wished he would've included in the story. All that and more.

In this episode I talk to a good friend of mine and massively experienced business owner Ian Preston, he owns an estate agents, a planning business, architectural company a tech business just to name a few. Ian has so much knowledge to give and shares valuable knowledge in this NOT TO BE MISSED episode

With nearly 95% of our oceans still unexplored, it's hard to imagine what's lurking deep under water. But thanx to deep-sea cameras, advanced technology and amazing enthusiasm, we know that there're pretty incredible creatures that live deep in the ocean. In this video I'm gonna show you the largest sea inhabitants! One of them is a jellyfish that can compete with the blue whale's epic proportions! You'll also meet a huge prehistoric reptile that lived in the waters all over the world! Read more: https://brightside.me/articles/9-incr... #brightside Credit: CC BY-SA 2.0 https://creativecommons.org/licenses/... Jellyfish and shark: By Tim Evanson - https://flic.kr/p/batHCP, https://commons.wikimedia.org/w/index... The lion's mane jellyfish: By Derek Keats - https://flic.kr/p/yAbtDH, https://commons.wikimedia.org/w/index... Physalia physalis: By Auckland Museum Collections - https://flic.kr/p/2hg6qf3, https://commons.wikimedia.org/w/index... Elasmosaur skeleton: By Eden, Janine and Jim - https://flic.kr/p/KY6ZWN, https://commons.wikimedia.org/w/index... Psittacosaurus gastroliths: By Ryan Somma - https://flic.kr/p/5miJX1, https://commons.wikimedia.org/w/index... CC BY-SA 3.0 https://creativecommons.org/licenses/... Shastasaurus altispinus: By Dmitry Bogdanov, https://commons.wikimedia.org/w/index... Albertonectes vanderveldei: By Smokeybjb, https://commons.wikimedia.org/w/index... Platypterygius kiprjianovi: By Creator: Dmitry Bogdanov, https://commons.wikimedia.org/w/index... By Ghedoghedo: Fossil of Ophthalmosaurus, an extinct reptile, https://commons.wikimedia.org/w/index... Fossil of Ophthalmosaurus, https://commons.wikimedia.org/w/index... OphthalmosaurusIcenius: By Captmondo, https://commons.wikimedia.org/w/index... Styxosaurus swim cycle: By Johnson Mortimer - https://www.deviantart.com/johnson-mo..., https://commons.wikimedia.org/w/index... CC BY-SA 4.0 https://creativecommons.org/licenses/... Oceanic Manta: By Stevelaycock21, https://commons.wikimedia.org/w/index... Faja, Faial, Azoren: By Peiner1, https://commons.wikimedia.org/w/index... Plesiosaur: By Andy Dingley, https://commons.wikimedia.org/w/index... Albertonectes vanderveldei gastroliths: By Ghedo, https://commons.wikimedia.org/w/index... Tellus Mosasaurus: By Jonathan Chen, https://commons.wikimedia.org/w/index... Fossil mosasaur: By Ghedoghedo, https://commons.wikimedia.org/w/index... Animation is created by Bright Side. ---------------------------------------------------------------------------------------- Music by Epidemic Sound https://www.epidemicsound.com Check our Bright Side podcast on Spotify and leave a positive review! https://open.spotify.com/show/0hUkPxD... Subscribe to Bright Side: https://goo.gl/rQTJZz ---------------------------------------------------------------------------------------- Our Social Media: Facebook:   / brightside   Instagram:   / brightside.official   TikTok: https://www.tiktok.com/@brightside.of... Stock materials (photos, footages and other): https://www.depositphotos.com https://www.shutterstock.com https://www.eastnews.ru ---------------------------------------------------------------------------------------- For more videos and articles visit: http://www.brightside.me Learn more about your ad choices. Visit megaphone.fm/adchoices

Ed Sheeran - Eyes Closed (00:00 - 03:09) Jacob Collier - Little Blue (03:09 - 11:04) Bongeziwe Mabandla - Noba Bangathini (11:04 - 13:56) Flyte & Florence Pugh - Tough Love (13:56 - 16:42) Mahalia - Lose Lose (16:42 - 20:38) The Teskey Brothers - Carry Me Home (20:38 - 24:35) Madison Cunningham - All I've Ever Known (24:35 - 29:27) Myles Smith - I Found (29:27 - 33:32) Matt Maeson - Cry Baby (33:32 - 36:55) Kim Churchill & Steph Strings - Please Come Home (36:55 - 40:50) SOLOMON - Do You Want My Love? (40:50 - 43:53) Gabrielle Aplin - Skylight (43:53 - 47:21) All uploads on this channel are for promotional purposes only! The music has been converted before uploading to prevent ripping and to protect the artist(s) and label(s). If you don't want your content here  please contact us immediately via email: allmusiclive@outlook.com and WE WILL REMOVE THE EPISODE IMMEDIATELY! 

The script consists of a vibrant discussion on various subjects involving pop culture, such as the impact of problematic pasts on employment and personal perception, the increasing trend of digitally remaking and skin color-swapping existing characters, Martin Luther King Jr. and Nancy Reagan in a hypothetical adult movie scenario, Taylor Swift's influence in the media and football scene, potential Artificial Intelligence control in future telecommunication systems, and shared observations on popular celebrity adult tapes. The language and comedy are often explicit and unfiltered.

As you wrapped yesterday up, you should have said to yourself, as Seneca did each night, “that's it.” I have lived my life. As you tucked your children in last night, you should have said to yourself, as Epictetus and Marcus Aurelius did, this might be the last time.The memento mori medallion , memento mori signet ring And the memento mori pendant, All these were created to remind us that we must live NOW, while there is still time.-⏳ You can view our entire Memento Mori Collection at dailystoic.com/mm✉️ Sign up for the Daily Stoic email: https://dailystoic.com/dailyemail

wah gwan friends?! We're so happy to see you again this week and continue our series called, Sacred Smokes! Today, we are discussing Sweetgrass. It is native to North American and used by First Nations/indigenous peoples of North America AND by many Black populations such as the Gullah Geechee. This plant has sooo much to teach us and I hope you are as eager as we are to take on some of those lessons! Grab ya sweet tea and join us for the ride!  As always, we want to thank you for all of your support, in all the ways! we're trying to build up this patreon, so that we can sustainably fund the work we already do with the podcast. so if you're not yet a patreon, join today @ ⁠patreon.com/pettyherbalist⁠. Sources and what's In the episode: (herb) Sweetgrass (Hierochloe odorata) (yoga posture) legs up the wall (herb) passiflora caerulea tincture (book) Braiding Sweetgrass by Robin Wall Kimmerer (website) Where to buy Sweetgrass, ethically (article) Sacred Teachings of Sweetgrass (journal) Coumarin Compound Summary ________________________ Follow us on social: ⁠@pettyherbalist⁠ ⁠@bonesbugsandbotany⁠ Join the Patreon Community to fund this amazing POD: ⁠https://www.patreon.com/pettyherbalist⁠ Join the bonesbugsandbotany Patreon Community to fund support all of Asia's work: ⁠⁠⁠https://www.patreon.com/bonesbugsandbotany⁠⁠ Rate us to show your support! Thank You! #StayReady #BePetty ***if you read this far, send me a dm @pettyherbalist for a shoutout!*** --- Send in a voice message: https://podcasters.spotify.com/pod/show/pettyherbalist/message Support this podcast: https://podcasters.spotify.com/pod/show/pettyherbalist/support

PHOTO: 1900 Ireland NO KNOWN RESTRICTIONS ON PUBLICATION. @BATCHELORSHOW BETTER PLANET THAN WE HAVE EVER KNOWN:  4/4  A Dog's World: Imagining the Lives of Dogs in a World without Humans, by Jessica Pierce and Marc Bekoff  https://www.amazon.com/Dogs-World-Imagining-without-Humans/dp/0691196184 What would happen to dogs if humans simply disappeared? Would dogs be able to survive on their own without us? A Dog's World imagines a posthuman future for dogs, revealing how dogs would survive―and possibly even thrive―and explaining how this new and revolutionary perspective can guide how we interact with dogs now.

PHOTO: 1650 NO KNOWN RESTRICTIONS ON PUBLICATION. @BATCHELORSHOW BETTER PLANET THAN WE HAVE EVER KNOWN:  3/4  A Dog's World: Imagining the Lives of Dogs in a World without Humans, by Jessica Pierce and Marc Bekoff  https://www.amazon.com/Dogs-World-Imagining-without-Humans/dp/0691196184 What would happen to dogs if humans simply disappeared? Would dogs be able to survive on their own without us? A Dog's World imagines a posthuman future for dogs, revealing how dogs would survive―and possibly even thrive―and explaining how this new and revolutionary perspective can guide how we interact with dogs now.

PHOTO: 1650 NO KNOWN RESTRICTIONS ON PUBLICATION. @BATCHELORSHOW BETTER PLANET THAN WE HAVE EVER KNOWN:  1/4  A Dog's World: Imagining the Lives of Dogs in a World without Humans, by Jessica Pierce and Marc Bekoff  https://www.amazon.com/Dogs-World-Imagining-without-Humans/dp/0691196184 What would happen to dogs if humans simply disappeared? Would dogs be able to survive on their own without us? A Dog's World imagines a posthuman future for dogs, revealing how dogs would survive―and possibly even thrive―and explaining how this new and revolutionary perspective can guide how we interact with dogs now.

PHOTO: 1650 England NO KNOWN RESTRICTIONS ON PUBLICATION. @BATCHELORSHOW BETTER PLANET THAN WE HAVE EVER KNOWN:  2/4  A Dog's World: Imagining the Lives of Dogs in a World without Humans, by Jessica Pierce and Marc Bekoff  https://www.amazon.com/Dogs-World-Imagining-without-Humans/dp/0691196184 What would happen to dogs if humans simply disappeared? Would dogs be able to survive on their own without us? A Dog's World imagines a posthuman future for dogs, revealing how dogs would survive―and possibly even thrive―and explaining how this new and revolutionary perspective can guide how we interact with dogs now.

I'm unable to relax unless I'm doing something well. --- Support this podcast: https://podcasters.spotify.com/pod/show/modernblackman/support

Writer and podcaster Nora McInerny (Terrible, Thanks for Asking) explains why she is the saddest happy person she knows; music entrepreneur Nabil Ayers chats about his memoir My Life in the Sunshine and his estranged relationship with his biological father, funk/soul musician Roy Ayers; and singer-songwriter Madison Cunningham gives a show-stopping performance of her song "All I've Ever Known” from her Grammy-winning album Revealer. Plus, host Luke Burbank and announcer Elena Passarello discuss the ways in which we are too hard on ourselves.

We've made you wait for us, but we're finally talking about the Tony and Grammy award winning musical, Hadestown! Join Tara and Stefania as they break down both the Broadway and Mirvish production of the Anais Mitchell's retelling of the classic myth. So hop in the car and join us on the way down to Hadestown! . . . "When the Chips are Down" - Hadestown (Original Broadway Cast Recording) "Chant" - Hadestown (Original Broadway Cast Recording) "Wait for Me" - Hadestown (Original Broadway Cast Recording) "Why We Build the Wall" - Hadestown (Original Broadway Cast Recording) "All I've Ever Known" - Hadestown (Original Broadway Cast Recording) "Road to Hell" - Hadestown (Original Broadway Cast Recording) "Doubt Comes In" - Hadestown (Original Broadway Cast Recording) "Nobody's Side" - Wild and Free - Jessica Vosk "In Memoriam Grammy's 2022" - Youtube All music tracks used for educational and entertainment purposes only.

We read multiple responses to this question, one of which says, “I had a coworker or employee in high school who went missing for 3 days. Turned out he went on a walk without telling anyone. A tree had fallen on him and was unable to free himself. He was dehydrated and shaken when they found him, but he recovered and came back to work a few days later.” Submit your stories: popmediaagency@gmail.com Go to greenchef.com/pop50 and use code pop50 to get 50% off plus free shipping.Our Instagram page: @reddit_explains

In this short episode, I talk with my brother of experience, Jim and his wife Keiko about all the reasons why we love our father! I also am able to bring in a special guest, my father's great grandson, Jim's grandson, my great nephew, Landon James to talk about his “Old Papa”

Welcome to Poetry Walks! A podcast that brings poems from our hearts to your ears. Center yourself through imaginative and calming poems as Arlo guides you through the city. Step within through these relaxing poems that question existence, friendship, activism, love, and self-worth. This episode features words by my dear friend, Luna Silver. To find more of Luna's projects you can visit their instagram. For a full transcript of today's episode visit arlotomecek.com under the sound section or https://poetrywalks.wordpress.com/ Land Acknowledgement: This podcast was released initially on forcibly ceded Munsee-Lenape land. You can learn more about land acknowledgement through the links below: https://native-land.ca/ https://www.whose.land/en/ https://library.chatham.edu/whoseland https://rethinkingplace.bard.edu/ Land acknowledgement is a way of showing historical accuracy, transparency, and honoring First Nations of this land. While land acknowledgement is not enough on its own, we invite you do the research and understand the multiplicity of histories under your feet. Thank you for listening to Poetry Walks! To submit your work, you can do so by emailing arlotomecek@gmail.com. To help this podcast, you can review and rate us on Apple Podcasts.

Shayne and Max get back to Talking About Nothing

Send us a Text Message.Genghis Khan, the man, the myth, the legend was undoubtedly a fierce and ruthless warrior. The New York Times called him “the original bad boy of history” and tales of his conquests have inspired shock and awe for much of the last millennium. During his reign as Khan of the vast Mongol empire, as many as 40 million people were killed. That's roughly 11 percent of the world population at the time. He showed no mercy to his enemies, wiping them out by the millions, sometimes slaughtering every man, woman, and child in the cities he conquered. But was he a bloodthirsty madman or an ingenious diplomat? Did you know that despite all the killing, Genghis Khan's empire was far more civil than the rest of the world? Let's fix that. Sources: History Channel "Genghis Khan"Metropolitan Museum of Art "The Legacy of Genghis Khan"Live Science "Who was Genghis Khan, the warrior who started the Mongol Empire?" IFL Science "Fact Check: Are 1 in 200 people descended from Genghis Khan?"History Channel "10 things you may not know about Genghis Khan"American Museum of Natural History "Empire of the Horse"History Channel "8 brutal acts of Genghis Khan and his successors"How Stuff Works "Did Genghis Khan really kill 1,748,000 people in one hour?"Uncharted Territories "The Hidden Rule of Empire Size"Science Direct "The Genetic Legacy of the Mongols"Mongol History "The Rescue of Borte"Encyclopedia Britannica "Mongol Empire"The Life Guide "Genghis Khan Explained in 8 Minutes"Support the show! Buy Me a CoffeeVenmo @Shea-LaFountaine

Savvy corporate players have a good chance of climbing up the corporate ladder and unlocking the achievement level of… VICP (Very Important Corporate Person). This coveted level of the work game translates into making good money, having power and influence at work, leading and inspiring teams, and flying business class, baby!Once you get to this point of corporate stardom, it's hard to walk away. But that's exactly what our guest did.  Christine Escribano is the former SVP of One Platform Marketing of NBC Universal, a company she loved and worked for over 14 years. However, during the last few years, she slowly but surely felt compelled to make a major life shift.  Christine gave it all up to start her own interior design and furniture artist business, which began as a pandemic side hustle.In this episode, Christine shares her insights on how to plan a corporate exit strategy and she talks about the tools corporate gave her to be prepared for this new phase of her life. ------ Check out Christine's awesome store here. Book  her spectacular rental vacation home "Casa Di Amici" here.-----Check out Surfing Corporate's website and sign up for our newsletter. ------Episode Credits:Hosts: Aileen Merciel and Glenda PaninsProduction and editing: Aileen MercielIntern: Stephany Gil de SucherOriginal Theme song: Chaliwa Music.Other music: BlueDot Sessions 

The BEST Football Scout I ever knew passed away this week as the annual Scouting Convention of sorts was taking place in the annual visit to the Senior Bowl in Mobile, AL. Bobby Beathard helped to build multiple Championship level rosters with 5 NFL Teams. Lean about the man and what made him so great from his good friend and partner on the Scouting Road for so many years. Chris Landry spent many days working with Beathard and on the road while competing for talent and shares some of the great stories and qualities that only he would know. Landry Football Podcast Network brings you a Coaching & Scouting perspective on College Football, NFL, Recruiting, NFL Draft, Coaching Searches and much more. Subscribe, Rate & Review to the LANDRY FOOTBALL PODCAST NETWORK wherever you get your podcasts. Get inside the game and see the game through the eyes of a Coach & Scout over at www.LandryFootball.com . Your one stop Shopping Football Analysis Shop. If you have not yet tried out LandryFootball.com, get the same inside information that NFL teams and College Football programs get from a veteran Coach/Scout/Administrator on both the college and NFL level. Try it our for a month or take advantage of our Savings Discount on our yearly plan. LandryFootball.com ---put it in your browser and bookmark it for all the latest Inside Information as well as Coaching/Scouting Analysis from Chris Landry. Follow on Social Media---Twitter= @LandryFootball, FaceBook = LandryFootball, Instagram= LandryFootball Learn more about your ad choices. Visit megaphone.fm/adchoices

Host Luke Burbank and announcer Elena Passarello discuss the ways in which we are too hard on ourselves; writer and podcaster Nora McInerny (Terrible, Thanks for Asking) explains why she is the saddest happy person she knows; music entrepreneur Nabil Ayers chats about his memoir My Life in the Sunshine and his estranged relationship with his biological father, funk/soul musician Roy Ayers; and singer-songwriter Madison Cunningham gives a show-stopping performance of her song "All I've Ever Known” from her Grammy-nominated album Revealer.

STRONG Life Podcast ep 340 This is Iron Roots Episode 2 I take you on a trip back in time to learn about the MOST BadAss Gym EVER Known to Man, Zuver's Gym.  Brought to you by http://ZachStrength.com - Get your FREE Training Courses and a 20% Discount Coupon for The Underground Strength Store Recommended Resources: Old School Bodybuilding Course Minimalist Training Course Beginner Strength Program Thank you for listening, sharing and leaving a 5 star review!

Waterfowl guide and snow goose crazy man Jake Wightman stops by to school us on snow goose diy trips, Canadas, and cranes. This episode is packed with useful knowledge on hunting all types of waterfowl. We also hear a couple crazy stories about his time as a guide.  NEW MERCH IS OUT:  /SHOP Podcast is brought to you by our partner Soundgear. Check them out here: Soundgear Don't forget to leave a review and subscribe!