Podcasts about 1A

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Latest podcast episodes about 1A

1A
The News Roundup For October 10, 2025

1A

Play Episode Listen Later Oct 10, 2025 85:22


President Donald Trump threatened to invoke the Insurrection Act this week. He continues to clash with state and municipal authorities over the limits of his abilities to send Immigration and Customs Enforcement agents into American cities.Meanwhile, Republicans in Congress are eyeing their Democratic counterparts, looking for someone from the opposition to join them in voting for a bill that would reopen the government, more than a week into a shutdown.Former FBI Director James Comey was arraigned this week, pleading not guilty on Wednesday to charges that he lied to Congress, and saying he would move to have a court dismiss the case.Meanwhile, the first phase of a peace deal between Israel and Hamas was agreed to this week. But questions remain over how both parties will move forward with the details of the agreement.Despite a friendly summit between Russian President Vladimir Putin and President Donald Trump in Alaska in August, the Russian government is claiming that any headway made during that meeting has largely been undone.And after just 28 days, Sébastien Lecornu's time as France's prime minister came to an end this week. He's President Macron's fifth government leader to head for the exit in less than two years.Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

Movin' the Chains
Carvers Bay's Winning Formula: In-Season with Coach Matthew Richard

Movin' the Chains

Play Episode Listen Later Oct 9, 2025 15:51


The Carvers Bay Bears are 7–0 (3–0 in region 6-1A) and rolling under Head Coach Matthew Richard, now in his 7th season leading the program.After a first-round playoff exit last year, the Bears are back with 18 seniors and a renewed focus — and they're aiming to make a deep postseason run.Coach Richard joins Movin' The Chains to discuss:

1A
The US-Backed Plan To End The War In Gaza

1A

Play Episode Listen Later Oct 8, 2025 42:23


It's been two years since Hamas fighters killed 1,200 people and seized more than 250 hostages from inside Israel.More than 67,000 Palestinians have been killed in Israel's retaliatory war. On Monday, Israeli and Hamas negotiators met in Egypt to discuss President Donald Trump's 20-point plan to end the war in Gaza.Over the weekend, thousands of Israeli citizens took to the streets in Tel Aviv in support of a deal to release the hostages and end the war in Gaza.What do we know about the U.S.-backed plan to end the war in Gaza? And what does this plan mean for Israelis and Palestinians two years into this conflict? Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

The Mind Killer
145 - Shutdoooooown! Or Did Trump Bring Peace to the Middle East?

The Mind Killer

Play Episode Listen Later Oct 8, 2025 53:59


Wes, Eneasz, and David keep the rationalist community informed about what's going on outside of the rationalist communitySupport us on Substack!News links:Youtube is the latest company to give Trump a payoffHegseth sent 200 national guard troops to PortlandE.J. Antoni nomination to BLS withdrawnHHS said it is referring Harvard for suspension and debarment proceedings.Trump defunding the ethics watchdogspaused $2.1B in federal funds for Chicago infrastructure projectsTrump made an Israel-Hamas peace plan?James Comey indictedTrumpRX is apparently going to be a thingFederal Judge: Trump Administration violated 1A by deporting Palestinian sympathizersHegseth called in all the generals to tell them they're too fatTrump apparently all-in on support for Ukraine.EA bought out by (among others) the Saudi Public Investment CorporationHappy News!San Fran Supervisor going YIMBY on business regulationsJames Web Space Telescope is now examining the atmospheric make-up of exoplanets!Denver's Support Team Assistance Response (STAR) program is working!city reports 45% decrease in street peopleRecent study in Lancet shows people dying from chronic diseases globally fell in four out of five nations between 2010 and 2019The 60th nation ratified the High Seas Treaty, meaning it'll soon become legally bindingChina has signed on to this one and a related treaty20% increase in kids getting school lunches in last five years, worldwideHuntington disease treated for the first time!Got something to say? Come chat with us on the Bayesian Conspiracy Discord or email us at themindkillerpodcast@gmail.com. Say something smart and we'll mention you on the next show!Follow us!RSS: http://feeds.feedburner.com/themindkillerGoogle: https://play.google.com/music/listen#/ps/Iqs7r7t6cdxw465zdulvwikhekmPocket Casts: https://pca.st/vvcmifu6Stitcher: https://www.stitcher.com/podcast/the-mind-killerApple: Intro/outro music: On Sale by Golden Duck Orchestra This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit mindkiller.substack.com/subscribe

Movin' the Chains
Week 7 Preview Show | 2025 South Carolina High School Football

Movin' the Chains

Play Episode Listen Later Oct 8, 2025 99:41


Week 7 Preview Show | 2025 South Carolina High School FootballCarolina Orthopaedic & Neurosurgical Associates Games of the WeekScott's Branch @ Cross (4:55-11:40)Christ Church @ Powdersville (11:41-18:34)Greenville @ Greenwood (18:35-26:18)James Island @ Summerville (26:19-35:38)Trinity Collegiate @ Wilson Hall (35:39-38:55)Additional SegmentsMerch (1:17-2:30)5A (39:51-52:46)4A (52:47-57:29)3A (57:30-1:03:57)2A (1:05:02-1:09:55)1A (1:09:56-1:14:10)SCISA (1:14:11-1:17:51)Pick'Em (1:18:47-1:19:45)Polls (1:19:46-1:33:20)

1A
1A-10.07.2025

1A

Play Episode Listen Later Oct 7, 2025 39:55


The Supreme Court begins its new term this week.It's agreed to hear cases on several hot button issues like tariffs, trans athletes in sports, and the use of presidential power.The rulings could change constitutional precedent as we know it. What's at stake in these cases?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1A
'If You Can Keep It': Trump's New Vision For The Military

1A

Play Episode Listen Later Oct 6, 2025 42:38


President Donald Trump and Defense Secretary Pete Hegseth outlined some stark changes to the U.S. military's policies and norms at last week's gathering of its top brass.From new standards that question the fitness of women in combat roles, to deploying the military to U.S. cities, the White House is outlining a new vision for the armed forces. It's also looking to eliminate existing channels to report abuse and harassment within the ranks and implement random polygraph tests.We talk through all these changes, how they affect our troops, and what they mean for civilians.Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ atplus.npr.org/the1a.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1A
The News Roundup For October 3, 2025

1A

Play Episode Listen Later Oct 4, 2025 83:06


After Congress failed to reach an agreement to keep the doors in Washington open, the government has shut down. This comes as tens of thousands of federal workers are set to exit the federal payroll due to firings and deferred buyout agreements.Secretary of Defense Pete Hegseth called all military generals to Quantico, Virginia, to listen to an address about his vision for the armed forces.President Donald Trump said he plans on sending troops to Portland, Oregon, to protect Immigration and Customs Enforcement agents working there.Meanwhile, overseas, President Trump and Israeli Prime Minister Benjamin Netanyahu unveiled a 20-point plan to end Israel's war in Gaza.Following multiple Russian incursions into NATO airspace, the alliance has stepped up its drone defense, with Ukraine sharing its expertise with Denmark.Venezuelan President Nicolas Maduro is ready to declare a state of emergency, as the U.S. military builds up presence in the Caribbean.Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

PuckSports
Why Julio Rodriguez and Cal Raleigh NEED to be superstars | Daily Puck Drop

PuckSports

Play Episode Listen Later Oct 3, 2025 91:09


On Friday's Daily Puck Drop, Jason “Puck” Puckett starts off the show being joined by the Go-2-Guy, Jim Moore and Chris Egan from KING 5 and it's all Mariners playoff fever!  The boys breakdown the excitement what's in the store this weekend on the sports calendar that includes the Mariners, Seahawks and even the Sounders in action Saturday night!   One worry for the guys though is the injury situation for Bryan Woo, it sure doesn't sound like he's going to pitch against Detroit, is there a chance he's not back at all?  After Puck and Jim say goodbye to Egan they welcome their handicapper TroyWins.com to give out his best picks for the weekend including his “Lock of the Week.” Puck then welcomes Todd Milles from VarsityWaNews.com “Friday Night Lights” to get a preview of the top high school games of the weekend.  Big matchup in 4A Wesco with Lake Stevens and Glacier Peak.  Todd is heading east to watch 1A powerhouse Royal vs. their arch rival Cashmere. Puck then switches gears over to the Seahawks and “The Last Word” with Bob Condotta of the Seattle Times.  Injuries continue to mount for the secondary and it's another game they will have to juggle the starters.  Riq Woolen's name has been brought up in trade speculation, how realistic is it that the Seahawks move on from there one time Pro Bowl corner?  Puck wraps up the show with “Hey, What the Puck!?”   Superstars win games and carry teams. The Mariners have two of the best in Cal Raleigh and Julio Rodriguez. (1:00) Puck, Jim and KING 5's Chris Egan (44:02) Troy Wins, PuckSports handicapper  (55:00) Todd Milles, Varsitywanews.com  (1:08:30) Bob Condotta, Seattle Times (1:26:22)  “Hey, What the Puck!?”  

ChipChat
Chip got shutdown

ChipChat

Play Episode Listen Later Oct 3, 2025 107:16 Transcription Available


With the government shutdown Chip was forced to take a week off to atone for whatever he did to cause it. Tez and Bryan handle the week's news with headlines. Tez explains the shutdown, Trump loses in court, a bunch more times, and the show finishes on time!Become a supporter of this podcast: https://www.spreaker.com/podcast/chipchat--2780807/support.

1A
The Link Between Misogyny And Violent Extremism

1A

Play Episode Listen Later Oct 2, 2025 36:13


How does hatred towards women relate to violence?We've seen more than a few incidents of political extremism and mass violence in the U.S. over the last few years.In the days, weeks, and months after acts like these, we seek motives. We try to understand why violence is perpetrated in hopes of preventing it in the future.One expert argues that in that search for answers – we're missing something crucial. Something that keeps us from addressing this violence and extremism head on. That blind spot is misogyny.We sit down with Cynthia Miller-Idriss. She is a sociologist and founding director of the Polarization and Extremism Research & Innovation Lab, or PERIL at American University. She's also the author of “Man Up: The New Misogyny and the Rise of Violent Extremism.” She joins us to talk about her book and latest research.Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1A
Checking In On The Federal Workforce As The Government Shuts Down

1A

Play Episode Listen Later Oct 1, 2025 30:22


The White House is continuing its mission to hollow out the federal workforce. The Trump administration has signaled that it will use the government shutdown to prompt and encourage mass resignations and layoffs.More than 150,000 federal employees plan to leave the U.S. government payroll this week. It's the largest single-year exodus of federal workers since World War II.For workers who opted into the deferred exit program, those resignations began on Tuesday. Workers who didn't take the buyouts were recently threatened with dismissal.We check in on the state of the federal workforce. What happens now that tens of thousands of these employees are leaving? And what's life like for those who remain?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a.  Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

Movin' the Chains
Week 6 Preview Show | 2025 South Carolina High School Football

Movin' the Chains

Play Episode Listen Later Oct 1, 2025 95:27


Week 6 Preview Show | 2025 South Carolina High School FootballCarolina Orthopaedic & Neurosurgical Associates Games of the WeekCarvers Bay @ Latta (4:26-13:56)Strom Thurmond @ Batesburg-Leesville (13:57-22:31)Loris @ Dillon (22:32-32:36)Berkeley @ Stratford (32:37-41:38)Bethesda @ Beaufort Academy (41:39-45:41)Additional SegmentsMerch (1:08-2:07)5A (46:42-59:15)4A (59:16-1:05:09)3A (1:05:10-1:10:35)2A (1:11:46-1:15:25)1A (1:15:26-1:19:16)SCISA (1:19:17-1:21:40)Pick'Em (1:22:36-1:24:05)Polls (1:24:06-1:30:30)

1A
How Spending Time In Nature Helps Our Health

1A

Play Episode Listen Later Sep 30, 2025 33:08


Many of us know that being outside feels good. Maybe it's for a short walk to the store. Maybe for a hike at a nearby mountain. Or maybe spending time at the beach with loved ones for a holiday.But did you know that a short walk in nature can improve your attention span by 20 percent? And that even fake plants have been shown to deliver health benefits? There are real benefits to surrounding yourself with the natural world. We sit down with the pioneer of environmental neuroscience, Marc Berman. He's out with a new book all about the science behind the benefits spending time outside called “Nature and the Mind.”Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1A
Why Are Russian Aircraft Violating NATO Airspace?

1A

Play Episode Listen Later Sep 30, 2025 21:44


NATO's airspace is busy these days. And not in a good way. That's especially true for member nations on the alliance's eastern flank.It's not supposed to be that way. In recent weeks, states like Poland, Estonia, Romania, and Denmark have seen drones or other aircraft violate their airspace. In some cases, these airborne craft clearly identify they're Russian in origin.Multiple countries have called on NATO to consult about what to do next. So, what's going on? What is Russia up to?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1A
'If You Can Keep It': James Comey And The Justice Department

1A

Play Episode Listen Later Sep 29, 2025 40:50


President Donald Trump has, according to many legal experts, crossed the Rubicon.After years of railing against his perceived enemies and publicly threatening to use the government for revenge, he's pressured the Justice Department to bring charges against someone he hates despite warnings from top prosecutors.Late last week, a grand jury narrowly indicted former FBI Director James Comey on allegations that he lied to Congress in 2020. The 5-year statute of limitations was set to expire on Tuesday.So, how independent is the DOJ? And how much independence should it have? We talk about how the Justice Department is treating Trump's enemies and also how it's treated his friends.Find more of our programs online.Listen to 1A sponsor-free by signing up for 1A+ atplus.npr.org/the1a.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

Journal of Clinical Oncology (JCO) Podcast
JCO Article Insights: Phase I DLL3/CD3 T-Cell Engager in DLL3-Positive SCLC or NECs

Journal of Clinical Oncology (JCO) Podcast

Play Episode Listen Later Sep 29, 2025 12:51


In this JCO Article Insights episode, Dr. Ece Cal interviews Dr. Martin Wermke, author of the JCO article, "Phase I Dose-Escalation Results for the Delta-Like Ligand 3/CD3 IgG-Like T-Cell Engager Obrixtamig (BI 764532) in Patients With Delta-Like Ligand 3+ Small Cell Lung Cancer or Neuroendocrine Carcinomas." TRANSCRIPT The disclosures for guests on this podcast can be found in the transcript. Dr. Ece Cali: Welcome to this episode of JCO Article Insights. This is Dr. Ece Cali, JCO editorial fellow, and today I am joined by Dr. Martin Wermke, Professor for Experimental Cancer Therapy at Dresden University of Technology, to discuss the manuscript “Phase 1 Dose-Escalation Results for the Delta-Like Ligand 3/CD3 IgG-like T-Cell Engager Obrixtamig in Patients with DLL3+ Small Cell Lung Cancer or Neuroendocrine Carcinomas.” Obrixtamig is a bispecific T-cell engager that binds to DLL3 on tumor cells and CD3 on T-cells. This manuscript presents the phase 1A dose escalation results of Obrixtamig in patients with DLL3+ small cell lung cancer and neuroendocrine carcinomas. In this study, 168 patients were treated with Obrixtamig across four different dosing regimens. 49% of the patients had small cell lung cancer, 42% had extrapulmonary neuroendocrine carcinoma, and 8% had large cell neuroendocrine carcinoma of the lung. Patients received a median of two prior lines of therapy. 33% of the patients had brain metastases at baseline. Of note, this trial did not mandate baseline brain imaging. Maximum tolerated dose was not reached. 88% of the patients experienced a treatment-related adverse event, however, only 3.6% of the patients had to discontinue treatment due to treatment-related AEs, and dose reduction due to treatment-related AEs was documented in 2.4% of the patient population. Similar to the other DLL3-targeted bi-therapies, the most common adverse events included CRS in 57%, dysgeusia in 23%, and pyrexia in 21% of the patients. CRS events were mostly mild. They occurred more frequently in the first two to three doses. 9% of the patients experienced ICANS, of which 3% were graded as Grade 3 or higher. And let's review the efficacy results. Responses were only seen in patients who received 90 microgram per kg or more once weekly or once every three weeks dosing. The objective response rate in patients who received an effective dose was 28%. If we review by tumor type, 21% of the small cell lung cancer patients, 27% of the extrapulmonary neuroendocrine carcinoma patients, and 70% of the large cell neuroendocrine carcinoma patients had objective response. Median duration of response was 8.5 months, though this data is immature due to short follow-up. Dr. Wermke, DLL3-targeted bispecific T-cell engagers are reshaping the treatment landscape of small cell lung cancer. This trial investigates Obrixtamig in other high-grade neuroendocrine tumors as well. Can you put this trial into context for us and explain why it may represent an important step forward? Dr. Martin Wermke: Yeah, thank you for providing me with the opportunity to discuss our data today. I think the data with Obrixtamig in small cell lung cancer are largely similar to what has been observed with other bispecific T-cell engagers such as tarlatamab with respect to the response rate and duration. It has, however, been to be mentioned that BI 1438001 had a bit more liberal inclusion criteria than other trials around. You already mentioned the fact that we allowed the inclusion of patients without mandatory brain imaging, which led to some patients having their brain mets been diagnosed during the treatment with obrixtamig and then adding to the progressive disease patients. That is something which was not the case with the tarlatamab trials where you really had to have a brain imaging before, and in the Phase 1 trial you were even required to treat the brain mets before you included the patient. So it is a bit different, more poorest patient population. I think the trial adds on existing data by being the first trial to also include non-SCLC neuroendocrine carcinoma of other origin, for example from the gastrointestinal tract, and also by including large cell neuroendocrine carcinoma of the lung, which is a really hard to treat pulmonary neoplasm which currently lacks any standardized treatment. So that is really a step forward which we will build on in the future. Dr. Ece Cali: And one thing I would note in this trial, only patients with tumor expressing DLL3 were enrolled. Can you tell us a little bit more about this target, DLL3 in the context of neuroendocrine tumors, and does DLL3 expression predict clinical outcomes after treatment with DLL3 BiTEs, or do we actually need other predictive biomarkers for these novel agents? Dr. Martin Wermke: Yeah, thank you. That's a pretty interesting question. First of all, DLL3 is an atypical notch ligand, which is expressed by the majority of neuroendocrine carcinomas, virtually absent on healthy adult tissues. Therefore, turning it really into a bona fide target for T-cell engaging therapies, pretty low risk for on-target off-tumor side effects. We found that in all the patients we screened, we had an expression rate of about 94% in small cell lung cancer, 80% of large cell neuroendocrine carcinoma of the lung were positive, and also about 80% of the extrapulmonary neuroendocrine carcinoma. So it's really a high prevalence. So the fact that we only included DLL3+ tumors still means we included most of the patients that presented with these diseases. I think at the moment there are no data suggesting a clear-cut association between DLL3 expression levels and outcome on DLL3 CD3 T-cell engagers. There's also not a lot published. If you want to find this out for tarlatamab, you have to look into their patent to really see the data, but it's not clear-cut and I'm sure we need other markers to complement that. And I think what probably plays a major role is intrinsic T-cell fitness. So the question how really diseased your T-cells are, how old you are, because age also correlates with the fitness of the immune system, and other patient characteristics such as tumor burden, we've seen all across the board that the higher the tumor burden, the lower the rate of prolonged response is in such trials. And I also think we need to focus on other components of the tumor microenvironment. So see how high the T-cell infiltration with obrixtamig is and how abundant suppressive elements like regulatory T-cells or myeloid-derived suppressive cells are. That is work which is currently being done. Data are emerging, but I don't think that at the moment we have any clear biomarker helping us to select who should not receive DLL3 T-cell engagers. Dr. Ece Cali: Those are great points and there is a lot we need to learn about how to use these novel agents in the future. I'd like to highlight the results in large cell neuroendocrine carcinoma of the lung. The response rate in this group was remarkably high at 70%. Though we should note the small sample size of only 14 patients in this trial. After first line chemoimmunotherapy, current approved options for this population have very modest clinical activity. Given these trial results, how do you envision the field moving forward for patients with large cell neuroendocrine carcinoma? Dr. Martin Wermke: Yeah, I think LCNEC is really an area which urgently needs further improvement of therapeutic standards. At the moment, as I said, there is no real standard. We are usually extrapolating from results we have in small cell lung cancer or non-small cell lung cancer, but I don't think we have too many prospective trials really informing this. Of course, 14 patients is a small sample size, but I think it's still fair to say that we can claim that DLL3 T-cell engagers are not doing worse in LCNEC than they do in SCLC. And that's why I think we really need to move forward clinical trials that are specifically targeting this population. Although I fear a bit that, given the rareness of this disease and the aggressiveness of its phenotype, that this is probably not the main focus of the pharmaceutical industry. So I think it's up to us academic investigators to really come up with investigator-initiated trials trying to fill the knowledge gaps we have here. Dr. Ece Cali: And one more thing that I want to talk about is the accessibility for these drugs. These novel agents are showing real promise in improving outcomes for patients with high-grade neuroendocrine tumors, an area where progress has been limited until very recently. However, as DLL3 BiTEs become more widely used, issues of logistics and access come into sharper focus. With unique toxicities and the specialized monitoring, their use is restricted to certain centers. Looking ahead, what kinds of strategies could help mitigate some of these adverse events or make these treatments more broadly available? Dr. Martin Wermke: Yeah, I think if you look at countries like the United States where tarlatamab has already been approved, we can see how the management strategies are evolving. I've heard about a colleague equipping their patients with thermometers and a pill of Dexamethasone, alongside with a temperature control protocol and clearly instructing them, "If you measure a temperature above a certain level then start taking the Dexamethasone and come back to our office and we're going to take care of you." I think that's one way to move forward. I think we are lucky in a way that CRS usually manifests within the first 24 hours. This was the same in our study, like in the tarlatamab studies. So we really know when the time of trouble is for our patients. And in this time, I think we need to instruct the patients to stay close to the hospital. I don't think we need to hospitalize all of them, but we probably need them to stay in a nearby hotel to be able to reach the emergency room if needed in a short period of time. And I think we can also learn in this strategy how to manage bispecific antibodies from the experience our colleagues in hematology had because they have been using bispecific T-cell engagers for quite some years right now and they developed strategies and networks that were able to successfully treat these patients also on an outpatient basis. And I think that is clearly an experience we need to follow, acknowledging that we are talking about diseases which are much more frequent than the standard hematology indications. Dr. Ece Cali: Thank you so much, Dr. Wermke, for this informative discussion and for sharing your perspective on this evolving field. Dr. Martin Wermke: Yeah, thank you for providing me with the opportunity to talk about data. It was really great being able to share that, and I really think that we are just at the beginning of a new exciting area for the treatment of neuroendocrine carcinomas, and I think much improvement is yet to come for our patients. Dr. Ece Cali: Yes, that's really exciting. And thank you everyone for listening to JCO Article Insights. Please come back for more interviews and article summaries and be sure to leave us a rating and review so others can find our show. For more podcasts and episodes from ASCO, please visit asco.org/podcasts. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on this podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement. Dr. Martin Wermke's Disclosures Honoraria: Lilly, Boehringer Ingelheim, SYNLAB, Janssen, Merck Serono, GWT, Amgen, Novartis, Pfizer,  BMS GmbH & Co. KG, Regeneron, MJH/PER, Takeda Consulting or Advisory Role: Bristol-Myers Squib, Novartis, Lilly, Boehringer Ingelheim, ISA Pharmaceuticals, Amgen, immatics, Bayer, ImCheck therapeutics, AstraZeneca, Tacalyx, Regeneron, Daiichi Sankyo Europe GmbH, Zymeworks, PharmaMar, Iovance Biotherapeutics, T-Knife, Genentech Research Funding: Roche Patents, Royalties, Other Intellectual Property Travel, Accommodations, Expenses: Pfizer, Bristol-Myers Squibb, AstraZeneca,  Amgen,  GEMoaB, Sanofi/Aventis, immatics,  Merck Serono, Janssen Oncology, Iovance Biotherapeutics, Daiichi Sankyo Europe GmbH"

Back Roads
Back Roads 2025: Episode 7

Back Roads

Play Episode Listen Later Sep 28, 2025 48:41


It's another exciting episode with game scores, player stats, and week 6 games coming up. The Wesp entertains us, and we follow up with news & notes around 1A. Top 25 Volleyball rankings are updated - district starts soon!Join us!

1A
The News Roundup For September 26, 2025

1A

Play Episode Listen Later Sep 26, 2025 85:26


A gunman opened fire at an ICE detention facility in Dallas leaving one person dead and two more injured. All three of the victims were detainees and no ICE agents were hurt. The shooter was found dead according to senior law enforcement officials.Late night host Jimmy Kimmel returned to the air on ABC this week. He was suspended after he made comments concerning the death of conservative activist Charlie Kirk.The deadline to pass the government funding bill  is fast approaching. The Trump White House is threatening mass firings if the government does shuts down.And, in global news, President Donald Trump addressed the United Nations General Assembly this week. In a nearly hour-long speech, he attacked the U.N., criticized the immigration policies of its member states, and called climate awareness the “greatest con job ever perpetrated on the world.”Spanish and Italian frigates were sent to protect the Global Sumud Flotilla. The boats carrying aid were attacked by drones on Tuesday.And in a meeting on the sidelines of the U.N. General Assembly, Donald Trump said Ukraine could win back all its territory taken by Russia with NATO assistance.We cover the most important stories here and around the globe in the News Roundup.Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ atplus.npr.org/the1a.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

TODAY
TODAY September 26, 3RD Hour: Investing 101 with Jim Cramer | Celebrating Jane Austen's 250th Birthday | Maura Tierney and Reid Scott in Studio 1A to discuss 25th Season of 'Law & Order'

TODAY

Play Episode Listen Later Sep 26, 2025 36:36


CNBC's Jim Cramer stops by 1A to discuss his new book coming out next week on 'How to Make Money in Any Market.' Also, NBC News' Raf Sanchez joins from across the pond to share the many celebrations underway for Jane Austen's 250th birthday. Plus, Maura Tierney and Reid Scott pop in to discuss more about the 25th season of 'Law & Order.' And, board-certified psychiatrist Dr. Sue Varma shares ways to find happiness during a change in seasons.  Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

1A
The Future Of Cancer Research In The US

1A

Play Episode Listen Later Sep 25, 2025 31:44


More than 50 years ago, President Richard Nixon declared war on cancer when he signed the National Cancer Act in 1971. Since then, the United States has emerged as a juggernaut in cancer research, funded largely by the government.But since President Donald Trump took office in January, the administration's sweeping cuts to the federal workforce and government funding are upending the country's research system.So, how are these funding and staffing cuts affecting cancer research and treatment? And how could they impact our progress towards scientific breakthroughs?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

TODAY
TODAY, Pop Culture & Lifestyle September 25: Regina Hall Discusses 'One Battle After Another' | Marking 25 Years Since Katie Couric's Colonoscopy | Shake and Bake Chicken Recipe

TODAY

Play Episode Listen Later Sep 25, 2025 31:06


Regina hall in 1A to discuss her role in the highly anticipated 'One Battle After Another.' Also, Katie Couric joins to celebrate her 25th anniversary since becoming the first person in history to broadcast a colonoscopy live on national TV and shares a first look into her new project aimed at saving more lives. And, chef Meredith Hayden prepares a shake and bake chicken recipe perfect for a crowd. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

1A
The Conditions In ICE Detention Centers

1A

Play Episode Listen Later Sep 24, 2025 31:02


A record number of people are being detained by Immigration and Customs Enforcement. And the conditions they're reporting have been described as cruel and inhumane.Last month, 60,000 people were detained by ICE, breaking a record set by the previous Trump administration. A Los Angeles Times analysis of public data found that more than a third of detainees have spent time in a dedicated facility that is over capacity.And now, county jails and ICE field offices are being transformed to fill those gaps. Jails held an average of about 10 percent of all detainees (7,100 people) each day in July, according to the Prison Policy Initiative.So, what fallout is the Trump administration's immigration crackdown having on ICE detention centers? What are the conditions in these centers like? And what legal options do detainees have?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

Movin' the Chains
Week 5 Preview Show | 2025 South Carolina High School Football

Movin' the Chains

Play Episode Listen Later Sep 24, 2025 94:25


Week 5 Preview Show | 2025 South Carolina High School FootballCarolina Orthopaedic & Neurosurgical Associates Games of the WeekClover @ Fort Mill (3:14-11:02)Seneca @ Daniel (11:03-19:05)Dorman @ Byrnes (19:06-26:01)Cheraw @ Central (26:02-33:21)Florence Christian @ Wilson Hall (33:22-36:45)Additional SegmentsMerch (1:43-2:36)5A (37:37-47:22)4A (47:23-56:40)3A (56:41-1:01:52)2A (1:03:00-1:06:52)1A (1:06:53-1:10:39)SCISA (1:10:40-1:14:45)Pick'Em (1:15:43-1:17:13)Polls (1:17:40-1:29:25)

TODAY
TODAY September 23, 3RD Hour: Fall Skincare Switch-Up | Zachary Quinto talks 'Brilliant Minds' | Teyana Taylor discusses 'One Battle After Another'

TODAY

Play Episode Listen Later Sep 23, 2025 36:18


Board-Certified dermatologist Dr. Angela Lamb breaks down how to revamp our skincare routines as fall is in full swing. Also, Zachary Quinto joins to discuss his medical drama 'Brilliant Minds' on NBC where he plays a doctor solving neurological mysteries.  Plus, critically acclaimed actress Teyana Taylor, is in 1A to talk about her highly anticipated film 'One Battle After Another.'  Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

1A
'If You Can Keep It': The Fight Over Funding The Government

1A

Play Episode Listen Later Sep 22, 2025 36:06


It happens every year — sometimes even more frequently than that.A fight is brewing over funding the government before a deadline at the end of September. On Friday, Republicans in the House of Representatives, led by Speaker Mike Johnson, passed a stop-gap measure to fund the government through Nov. 21.This is all happening against the backdrop of President Donald Trump's summer of immigration raids, the deployment of the National Guard to Washington D.C., and the claw back of approved federal funding.In this installment of 1A‘s weekly politics series, we talk about how this month's government funding fight could turn into a shutdown, and what Democrats could demand in exchange for keeping the government open.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

Ask Dr. Drew
Hate Speech Isn't Real: Why We DEFEND Horrible Speech Of Our Enemies w/ Robert Shibley (FIRE) + Curtis Houck (Newsbusters) & Jerome Hudson (Breitbart) – Ask Dr. Drew – Ep 533

Ask Dr. Drew

Play Episode Listen Later Sep 20, 2025 71:46


In a controversial post, AG Pam Bondi says “Hate speech that crosses the line into threats of violence is NOT protected by the First Amendment. It's a crime.” But does “hate” speech even exist under 1A? Laws to silence our foes today will be the same laws our foes use to silence us tomorrow. AG Bondi's post quickly received a Community Note: “The US Constitution protects most violent speech… The Supreme Court ruled it legal to “justify” or celebrate violence… but not “incitement” to “imminent” violence.” Even commenters from the Right were stunned that an admin official would propose a limit on the free speech of their political enemies: Chuck Garten writes “We must be very careful that our reaction to the Charlie Kirk shooting doesn't cause us to become the fascists that the left says that we are.” Robert Shibley is Special Counsel for Campus Advocacy at FIRE, the Foundation for Individual Rights and Expression. A Duke Law graduate, he served 19 years at FIRE, including six as executive director. He launched litigation initiatives, represented students and faculty, and authored “Twisting Title IX.” Follow at https://x.com/rshibley Curtis Houck is Managing Editor at NewsBusters. With over 10 years at the Media Research Center, he has made more than 600 TV appearances and 1,000 radio appearances. His work has appeared in Fox News, Breitbart, Drudge, The Federalist, and more. Follow at https://x.com/CurtisHouck Jerome Hudson is Entertainment Editor at Breitbart and author of “50 Things They Don't Want You to Know About Trump.” He covers the intersection of culture, politics, and entertainment. Learn more at https://breitbart.com and follow him at https://x.com/JeromeEHudson 「 SUPPORT OUR SPONSORS 」 Find out more about the brands that make this show possible and get special discounts on Dr. Drew's favorite products at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drdrew.com/sponsors⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠  ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠• FATTY15 – The future of essential fatty acids is here! Strengthen your cells against age-related breakdown with Fatty15. Get 15% off a 90-day Starter Kit Subscription at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drdrew.com/fatty15⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ • PALEOVALLEY - "Paleovalley has a wide variety of extraordinary products that are both healthful and delicious,” says Dr. Drew. "I am a huge fan of this brand and know you'll love it too!” Get 15% off your first order at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://drdrew.com/paleovalley⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ • VSHREDMD – Formulated by Dr. Drew: The Science of Cellular Health + World-Class Training Programs, Premium Content, and 1-1 Training with Certified V Shred Coaches! More at https://drdrew.com/vshredmd • THE WELLNESS COMPANY - Counteract harmful spike proteins with TWC's Signature Series Spike Support Formula containing nattokinase and selenium. Learn more about TWC's supplements at ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twc.health/drew⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠ 「 MEDICAL NOTE 」 Portions of this program may examine countervailing views on important medical issues. Always consult your physician before making any decisions about your health. 「 ABOUT THE SHOW 」 Ask Dr. Drew is produced by Kaleb Nation (⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://kalebnation.com⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠) and Susan Pinsky (⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠https://twitter.com/firstladyoflov⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠e⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠). This show is for entertainment and/or informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment. Learn more about your ad choices. Visit megaphone.fm/adchoices

1A
ICYMI: US Destroys Another Boat Coming From Venezuela

1A

Play Episode Listen Later Sep 19, 2025 11:41


Fourteen people are dead after the U.S. military launched strikes on two Venezuelan boats this month in international waters. President Donald Trump says they were heading towards the U.S.That's despite reports from several agencies saying the boat attacked two weeks ago was headed away from the U.S. when it was hit. Trump is also accusing the boats of being connected to Venezuelan drug trafficking cartels that he says posed a threat to the U.S.Venezuela's president, Nicolás Maduro, says the U.S. is trying to start a war.We discuss the stakes and what we know about the situation. Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1A
The News Roundup For September 9, 2025

1A

Play Episode Listen Later Sep 19, 2025 79:26


In a blow to free speech, TV host Jimmy Kimmel's late-night show was suspended from ABC's lineup after the comedian made jokes about President Donald Trump's relationship with the late conservative activist Charlie Kirk.The 22-year-old suspect in Kirk's killing was charged on  Tuesday in Utah County with aggravated murder. The state is seeking the death penalty.This week the president announced the National Guard will be deployed to Memphis, Tennessee.Meanwhile, a United Nations commission concluded that Israel is committing a genocide in Gaza against the Palestinian people.The UK rolled out the red carpet for President Trump during his visit with the royal family and Prime Minister Keir Starmer. In a press conference at the conclusion of the trip Trump said the two governments were making ties “closer than ever before.”Following recent Russian drone incursions in its own airspace, Poland suggests the European Union should set up a no-fly zone over Ukraine. Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a.  Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1A
ICYMI: FBI Director Kash Patel Appears Before Congress

1A

Play Episode Listen Later Sep 18, 2025 12:10


FBI Director Kash Patel appeared before the House Judiciary Committee on Wednesday for a second day of questioning by lawmakers.He faced questions about his leadership of the bureau including the firing of dozens of FBI agents and officials, the release of investigative files related to alleged sex trafficker Jeffrey Epstein, and the shooting of right-wing commentator Charlie Kirk.Patel began his hearings on Wednesday by defending the agency under his leadership. What were some of the biggest takeaways from the the hearing?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1A
ICYMI: Missouri Set To Sign A New Congressional Map Into Law

1A

Play Episode Listen Later Sep 17, 2025 11:49


Various states in the U.S. are locked in a fight over redistricting. It's all centered on which party will keep the House next year. Republicans now have a slim majority, 219 seats to 213.It started this summer when President Donald Trump asked Republicans in Texas to redraw the state's congressional maps early. The goal he said, was to improve Republicans' shot at winning five more seats in the House of Representatives during the 2026 midterm elections. After a standoff with Democrats in the state legislature, Republicans passed a map that did just that.Democrats in California, led by Gov. Gavin Newsom, responded with their own map. It's a redraw aimed at giving Democrats five more seats in the House. Newsom signed that bill into law in late August, saying it would “neutralize” what happened in Texas. Unlike Texas, California's map goes to the voters this November for approval. It would last through the 2030 elections.But the redistricting fights don't end there. Another GOP effort is nearing the finish line in Missouri. Republicans pushed a new map that will set them up to win seven seats instead of the usual six. Democrats currently hold two House seats in Missouri.Missouri Senate Republicans passed their redistricting bill on Friday. Now, it's at the desk of Republican Gov. Mike Kehoe for his signature. So, what does this mean for the state, the Democrats, and the midterms?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

Movin' the Chains
Week 4 Preview Show | 2025 South Carolina High School Football

Movin' the Chains

Play Episode Listen Later Sep 17, 2025 92:02


Week 4 Preview Show | 2025 South Carolina High School FootballCarolina Orthopaedic & Neurosurgical Associates Games of the WeekJohnsonville @ Lake View (4:40-11:20)Greenwood @ TL Hanna (11:21-20:11)Fairfield Central @ Newberry (20:12-25:08)South Pointe @ AC Flora (25:09-33:47)Dorchester Academy @ Beaufort Academy (33:48-37:12)Additional SegmentsMerch (1:11-2:05)5A (38:05-47:53)4A (47:54-56:30)3A (56:31-1:02:35)2A (1:03:45-1:09:01)1A (1:09:02-1:12:17)SCISA (1:12:18-1:16:38)Pick'Em (1:17:39-1:19:02)Polls (1:19:03-1:27:41)

1A
Mr. Trump Goes To Windsor

1A

Play Episode Listen Later Sep 16, 2025 11:32


British Prime Minister Keir Starmer broke the norm when he handed President Donald Trump an invitation for a second state visit.The pomp begins on Wednesday, and leadership across the pond is making no secret of its intention to woo President Trump. But there's more on the docket than making nice – and more at stake, too.What does the visit mean for both the U.S. And the UK?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1A
The News Roundup For September 12, 2025

1A

Play Episode Listen Later Sep 12, 2025 88:30


Republican provocateur and online personality Charlie Kirk was shot and killed while hosting an event at Utah Valley University this week. Despite authorities searching for the person responsible, no suspects are in custody.Donald Trump's takeover of the Washington D.C. police department expired Thursday evening. Trump signaled that he would seek an extension, but that desire has reportedly cooled.Meanwhile, in an attempt to harm Hamas, Israel bombed the Qatari capital of Doha this week. Israeli Prime Minister Benjamin Netanyahu signaled that he and his forces are prepared to do so again despite a rare condemnation of Israeli military strategy by the U.S.Poland invoked NATO's Article 4 this week after Russian drones entered its airspace, leading to consultations between representatives of the alliances member nations.France's government has collapsed again. Now, President Emmanuel Macron has appointed outgoing defense minister Sébastien Lecornu as the country's next prime minister.We get into all this and more during this week's News Roundup.Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1A
The Future Of Telehealth Abortions

1A

Play Episode Listen Later Sep 11, 2025 31:25


The nation's patchwork system of abortion laws is once again being challenged.This time, opponents are targeting telehealth abortions. That's when a provider in a state where abortion is legal meets virtually with a patient and sends them pills to take at home.Those patients come from states all over the country – even those with abortion bans. A quarter of all abortions in the U.S. are done via telehealth. That's according to a June report from the Society of Family Planning.Now, attorneys general in Texas and Louisiana are suing a doctor in New York for prescribing pills to patients in their states, where abortion is almost completely banned. New York is one of several states that's enacted shield laws after Roe was overturned. These statutes ban cooperation with other states' attempts to enforce abortion bans.Now that this has evolved into a battle between states, the Supreme Court is expected to weigh in soon. Their decision could drastically change access to abortion nationwide.So, what's at stake in this case? And how did states' rights become the latest flashpoint in the battle over abortion access?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1A
Trump's Battle With The Federal Reserve

1A

Play Episode Listen Later Sep 10, 2025 36:09


What's behind Donald Trump's ongoing battle with the Federal Reserve? That's the question on some analysts minds as the White House proposes staff shakeups at the historically independent central bank.Trump has been attempting to fire Federal Reserve Governor Lisa Cook since Aug. 25. Cook was nominated by Joe Biden and confirmed by the Senate in 2022.The administration is attempting to fire her based on allegations that she committed mortgage fraud before joining the Fed – that's despite the fact that she hasn't been convicted or charged with any crime.On Tuesday night, a federal judge temporarily blocked the president from removing Cook from the Federal Reserve's Board of Governors. She'll continue to serve as she contests her dismissal.The Fed has operated independently since its inception more than a century ago. How do the Trump administration's proposed changes threaten that independence? And what effect could changes at the Fed have on the U.S. economy?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1A
The Lawsuits Against The Trump Administration

1A

Play Episode Listen Later Sep 9, 2025 34:49


President Donald Trump has tested the limits of the law since the day he took office at the start his second term.This includes signing an executive order to end birthright citizenship, terminating or freezing billions of dollars in federal funding, and enacting sweeping tariffs on foreign goods without congressional approval.But these actions have not been met with silence.Over the last eight months, hundreds of lawsuits have been filed by state attorneys, physicians, media organizations, international students, and others to challenge the Trump administration's policies.We check in on major lawsuits against the administration. Where do they stand now? What do they mean for our country's system of checks and balances?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

Lee Hacksaw Hamilton
Padres Dodgers Fight to the Death, Chargers, Rams, NFL Week 1, Aztecs, USC, UCLA

Lee Hacksaw Hamilton

Play Episode Listen Later Sep 9, 2025 109:34


The Dodgers only lead the Padres by 1 game in the NL West. Which team has best chance to win division? We remember MLB player and manager Davey Johnson. Chargers rolled Chiefs on Friday night. Is the Chiefs era over? Lots of big games in the NFL Week 1 including Eagles, Rams, Ravens, Packers, Raiders, Bengals, Dolphins, Steelers, 49ers and Broncos. USC beats a cupcake while UCLA and San Diego State suffer defeats. Plus, news from Ohio State, Oregon, Utah and Fresno State. Trouble in the WNBA with Caitlin Clark and Angel Reese. Plus, Montreal Canadiens Ken Dryden, Carols Alcaraz, Max Verstappen and Christian Pulisic. Got a question or comment for Hacksaw? Drop your take in the live chat on YouTube, Facebook or X. Here's what Lee Hamilton thinks on Monday, September 8, 2025.   1)...PADRES-DODGERS WEIRD WEEK "FIGHT TO THE DEATH"   1A)...PADRES-DODGERS...19-GAMES LEFT "WHO PLAYS WHO"   LA..3-COLO               SD..3-CINN 3…SF                       4-COLO 3-PHI                       3...@NYM 4-SF                         3...@SOX 3…AZ                       3-MILW 3..SEA                      3-AZ   2)...MLB NOTEBOOK…METS/DAVEY JOHNSON "BASEBALL REMEMBERS"   3)...CHARGERS-CHIEFS...AN OPENING NIGHT TO REMEMBER "STATEMENT GAME-END OF ERA"   4)...NFL FIRST WEEKEND...BIG GAMES BY QBS-DEFENSES "OPEN WEEKEND = WAR"   EAGLES...RAMS RAVENS...PACKERS RAIDERS...BENGALS BENGALS...STEELERS 49ERS...BRONCOS =========== (HALFTIME...DIXIELINE LUMBER) =========== 5)...COLLEGE FOOTBALL...WEEKEND UPDATE…AZTECS/USC/UCLA "BLOWOUT WINS-BAD LOSSES"   6)...TOP TEAMS-TOP GAMES "BOMB JOBS"   OHIO STATE OREGON UTAH FRESNO STATE ----------- 7)...WNBA...BAD NEWS WITH BIG NAMES…CAITLIN CLARK/ANGEL REESE "INJURIES-SUSPENSION"   ----------- 8)...THE HOCKEY WORLD MOURNS…MONTREAL "KEN DRYDEN PASSES" ------------ 9)...HOT HEADLINES "OFF THE SPORTSWIRE"   CARLOS ALCARAZ MAX VERSTAPPEN CHRISTIAN PULISIC ======================= #nfl #DOLPHINS #JETS #BILLS #PATRIOTS #RAVENS #BROWNS #BENGALS #STEELERS #TEXANS #COLTS #TITANS #CHIEFS #CHARGERS #RAIDERS #BRONCOS #EAGLES #COWBOYS #GIANTS #COMMANDERS #LIONS #PACKERS #49ERS #RAMS #SEAHAWKS #PADRES #yudarvish #jakecronenworth #DODGERS #tylerglasnow #yoshinobuyamamoto #tannerscott #sandiegostate #aztecs #seanlewis #sdsu #jaydendenegal #jacobbostick #ucla #usc #utah #oregon #GENOSMITH #PETECARROLL #justinherbert #quentinjohnston #joealt #matthewstafford #lamarjackson #justinfields #derrickhenry #aaronrodgers #patrickmahomes #joshallen #dakprescott #joeburrow #jordanlove #bonix #jalenhurts #CAMWARD #nhl #canadiens #kendryden #wnba #caitlinclark #angelreese #f1 #maxverstappen #teamusa #christianpulisic #carlosalcaraz #deshaunfoster #lincolnriley     Be sure to share this episode with a friend! ☆☆ STAY CONNECTED ☆☆ For more of Hacksaw's Headlines, The Best 15 Minutes, One Man's Opinion, and Hacksaw's Pro Football Notebook: http://www.leehacksawhamilton.com/ SUBSCRIBE on YouTube for more reactions, upcoming shows and more! ► https://www.youtube.com/c/leehacksawhamiltonsports FACEBOOK ➡ https://www.facebook.com/leehacksaw.hamilton.9 TWITTER ➡ https://twitter.com/hacksaw1090 TIKTOK ➡ https://www.tiktok.com/@leehacksawhamilton INSTAGRAM ➡ https://www.instagram.com/leehacksawhamiltonsports/ To get the latest news and information about sports, join Hacksaw's Insider's Group. It's free! https://www.leehacksawhamilton.com/team/ Thank you to our sponsors: Dixieline Lumber and Home Centers https://www.dixieline.com/  

1A
'If You Can Keep It': HHS Versus The Science

1A

Play Episode Listen Later Sep 8, 2025 43:30


In recent weeks, we've seen a seismic shakeup inside the Department of Health and Human Services and unprecedented discord between the agency, scientists, and doctors.HHS Secretary Robert F Kennedy Jr. is bucking the science-backed guidance of physicians on vaccines. That's angered some Democrats. Vermont Sen. Bernie Sanders and Massachusetts Sen. Elizabeth Warren went after Kennedy over his pseudoscientific approach to running the agency during a Senate hearing Thursday.So, what happens when political ideology outweighs medical consensus?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1A
The News Roundup For September 5, 2025

1A

Play Episode Listen Later Sep 5, 2025 86:41


Jobs numbers are out. They indicate a stalling labor market, with U.S. employers adding just 22,000 jobs in August and unemployment rising to 4.3 percent.After rumors about the president's supposedly failing health swirled online last weekend, Donald Trump appeared in public at a press conference this week announcing the relocation of the Space Force headquarters from Colorado to Alabama.Florida announced this week that it's set to become the first state in the U.S. to end vaccine mandates in schools, including for young children.The leaders of China, India, Russia met this week in a display of friendship meant to signal unity to the world. Indian Prime Minister Narendra Modi, Russian President Vladimir Putin, and Chinese President Xi Jinping convened in China for a summit of powers not aligned with the West.Meanwhile, Putin told officials in Kyiv he was willing to try and negotiate the end the war in Ukraine should “common sense prevail.” However, he also threatened that he was prepared to continue should he not find terms agreeable.Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1A
What The 2025 US Open Says About The Future Of Tennis

1A

Play Episode Listen Later Sep 4, 2025 33:14


Every August, New York City becomes the headquarters for all things tennis thanks to the U.S. Open.And a lot has happened for the sport in the Big Apple. This year marks 75 since Althea Gibson broke the tennis color barrier at the tournament.So, ahead of the finals this weekend, we sit down with a panel of experts to talk about the biggest takeaways from this year's event and the future of the sport.Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1A
ICYMI: A Face-off Ahead Of Another Possible Government Shutdown

1A

Play Episode Listen Later Sep 3, 2025 11:45


Congress returned to the Capitol on Tuesday after their month-long summer break. They're already in a time crunch.Lawmakers have around four weeks – or around just 14 legislative days – to pass a spending measure and avoid a government shutdown before Sept. 30.Tensions between Republicans and Democrats are high. After the passages of President Donald Trump's spending and rescission bills, Democrats say they are ready for a fight. But the potential for being blamed for a government shutdown also puts them in a tough spot.On Tuesday, House Speaker Mike Johnson said the ball is in the Democrats' court, but will Republicans play ball at all?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1A
ICYMI: Earthquake Aftershocks Rock Afghanistan

1A

Play Episode Listen Later Sep 3, 2025 12:09


A 6.0 earthquake hit Afghanistan on Sunday night leaving more than 1,400 dead and at least 3,000 injured.Rescue crews struggled to reach affected villages in remote areas of the country's Kunar Province as powerful aftershocks continued to rattle the area.All of this is happening in a country already reeling from deep cuts to aid funding, a struggling economy, and an influx of millions of Afghans forcibly returned from Iran and Pakistan.Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a.  Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1A
The President And The National Guard

1A

Play Episode Listen Later Sep 2, 2025 33:06


Donald Trump says the office of the president gives him the right to deploy the National Guard to U.S. states. But does it? And who decides?The president signed an executive order last week calling for a restructuring of the National Guard. It also asks the nation's defense secretary to create a rapid response force to be deployed to states for “quelling civil disturbances and ensuring public safety.” Meanwhile, Trump says the city of Chicago is in need of National Guard presence due to a rise in crime. But the president has declined to say how the federal government can intervene outside of D.C., a federal enclave.Violent crime in Chicago is on a decline. In the first half of 2025, gun violence is down 25 percent compared to last year and down 41 percent from the average reported between 2020 and 2024. That data is from the CBS News Chicago Gun Violence Tracker. What could that deployment look like? And what has the response been from city officials? Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1A
1A Presents: Milk Street's Summer Lollapalooza

1A

Play Episode Listen Later Aug 31, 2025 33:45


We love talking about food at 1A. From the latest cookbooks to answering your questions about your favorite foods.As a holiday weekend treat and a fond look back at summer, we bring you highlights from an episode of Christopher Kimball's Milk Street Radio Podcast. The team discusses grilling and answer listener questions.Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a.Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

1A
The News Roundup For August 29, 2025

1A

Play Episode Listen Later Aug 29, 2025 84:47


A shooter opened fire in a Minneapolis church on Wednesday, injuring 17 people and killing two children. Parishioners and students were gathered at a Mass marking the first week of schoolA federal grand jury in the nation's capital this week declined to indict a man who threw a sandwich at a federal officer in Washington DC.Emails between top Florida officials show that they expect the state's newest immigration detention facility, dubbed “Alligator Alcatraz,” to be emptied in the coming weeks. The White House is fighting a judge's order to shut it down.Israeli and U.S. officials met this week in Washington to discuss plans for post-war Gaza. This comes as the Israeli military expands the offensive in Gaza City and they come under fire for a “double-tap” bombing of a hospital.In the war in Ukraine, both sides are attacking energy resources. In Europe, leaders sit down to try and negotiate peace in the region.Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

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New Orleans And Katrina, 20 Years Later

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Play Episode Listen Later Aug 28, 2025 43:11


It's been two decades since Hurricane Katrina ravaged New Orleans, making landfall in the city as a Category 3 storm. The massive storm surge broke through levees and the flood walls.Some 80 percent of New Orleans flooded. Entire neighborhoods were wiped out. The official death toll totaled nearly 1,400 people. And what happened in the storm's wake changed the face of emergency response in this country forever.We mark 20 years since Hurricane Katrina hit. We take you back to that time, look at what rebuilding has meant for New Orleans, and what lessons were learned.Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

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ICYMI: Trump Tries to Remove a Fed Governor

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Play Episode Listen Later Aug 27, 2025 11:54


President Donald Trump is ramping up his attacks on the Federal Reserve.On Monday, the president posted orders on Truth Social to remove Federal Reserve governor Lisa Cook – effective immediately. The president claims she committed mortgage fraud, an allegation first raised by a Trump loyalist and housing official.Cook, who was appointed by former President Joe Biden, responded in a statement saying that Trump has no authority to remove her and that she will continue her duties. Cook has not been charged with a crime.It's an unprecedented move that puts into question the independence of the central bank. So, what comes next and what does this mean for the Fed?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

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'If You Can Keep It': Trump Takes Aim At Mail-In Voting

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Play Episode Listen Later Aug 25, 2025 36:11


"Corrupt" is the word President Trump is using, without evidence, to describe mail-in voting. It's how almost one third of Americans cast their ballots in the last election.States including Florida and Pennsylvania also saw recent jumps in GOP mail-in ballots, after President Trump in his campaign called for votes by any means possible, including by mail.And while mail-in voting has historically favored Democrats, there is no evidence of the fraud Trump is claiming. But his push to end it fits a pattern: our President wants to change how elections are run in the United States.In this installment of our weekly series, “If You Can Keep It,” we get to the issue right at the very heart of U.S. democracy: the ability to cast a ballot in free and fair elections.Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy

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Why The FBI Searched John Bolton's Home And Office

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Play Episode Listen Later Aug 25, 2025 12:07


Another Friday, another move against a perceived enemy of the president.Last week, the FBI searched the Maryland home and Washington office of President Trump's former national security advisor, John Bolton.Since he was fired from the administration during Trump's first term, Bolton has turned into one of the president's most vocal critics.Vice President JD Vance confirmed in an interview that aired this weekend that this raid was in part connected to a criminal investigation over Bolton's handling of classified documents and information.What does this investigation say about the priorities of the Justice Department in Trump's second term?Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ at plus.npr.org/the1a. Learn more about sponsor message choices: podcastchoices.com/adchoicesNPR Privacy Policy