Podcasts about south american

A South American opponent in the quarterfinals does us in again. Mikey Varas's team played good soccer down in Argentina, but defensive lapses cost us on Sunday, and we lacked the cutting edge to overcome those. Matt Hartman joins to recap the game.----Scuffed is an ad-free podcast. Support that and get exclusive episodes once a week, plus access to the Discord and live call-in shows, by signing up for our Patreon: https://www.patreon.com/scuffed

AI is reviving voices of deceased musicians and creating new tracks by contemporary artists. The tech could mean job loss, especially for people in technical roles such as mixing and mastering. The DGA reached a possible deal with Hollywood studios over the weekend. How could this affect the striking film/TV writers? South American migrants were bussed from Texas to New Mexico, then flown to Sacramento. California's attorney general is evaluating criminal or civil action against people who sent those migrants. State lawmakers want to force big tech companies like Meta to pay for news articles that appear on their sites. Assemblymember Buffy Wicks sponsored a bill that would make this happen.

Episode 77: Frankie & Marcus recap Week 1 of the 2023 French Open, including how the Break Point Podcast Curse struck heavily in Week 1, the surprise runs of Elina Svitolina and South American clay courters, as well as our predictions for the rest of the tournament. Thanks for tuning in, make sure to follow and subscribe on all major podcasts & social media platforms! Socials ⁠Website⁠ ⁠Instagram⁠ ⁠Twitter⁠ ⁠LinkedIn⁠ ⁠YouTube⁠ --- Support this podcast: https://podcasters.spotify.com/pod/show/breakpointpodcast7/support

California Attorney General Rob Bonta blames Florida Governor Ron DeSantis for arranging a group of South American migrants to be transported from Texas to California and to be dropped off in Sacramento. The Hollywood Directors Guild has reached a deal with the studios as the writers' strike continues. According to John Carreyrou's book, "Bad Blood", Elizabtgher Holmes was obsessed with monitoring how many hours her employees were putting in and would order dinners for Theranos staff but made sure they weren't delivered until after 8 p.m. so they worked late.

AP correspondent Jackie Quinn reports on Texas Migrants Flown California

Photo: No known restrictions on publication. @Batchelorshow #NewWorldReport: Lula shepherds South American summit to include Nicholas Maduro Latin American Research Professor Evan Ellis, U.S. Army War College Strategic Studies Institute. @revanellis #NewWorldReportEllis https://www.reuters.com/world/americas/venezuelas-maduro-meets-lula-first-visit-brazil-since-2015-2023-05-29/

Peanuts have a long history tied to indigenous South American people, early traders,and slavery. It was African slaves who brought the peanut to Virginia and planted and harvested the first crop. Some of those early harvesting techniques are now being preserved by a 4th generation peanut farmer and a 3rd generation peanut company. We learn how on this episode about peanuts.Heritage Radio Network is a listener supported nonprofit podcast network. Support A Taste of the Past by becoming a member!A Taste of the Past is Powered by Simplecast.

Running order: - In depth look around the continent on the Copa Libertadores - All the latest news surrounding the Copa Sudamericana - A close look at the match odds for the U20 World Cup - South Americans in the English Premier League - how have the January signings fared? Want to get the edge in the markets on all things South American soccer? Listen and subscribe to Pinnacle's South American soccer insights. Follow the team on: Austin Miller: twitter.com/austin_james906 Peter Coates: twitter.com/Pedro_Coates Tom Robinson: twitter.com/tomrobbo89 Simon Edwards - @SimonEdwardsSAF Twitter - twitter.com/Pinnacle Instagram - Pinnacle.betting Facebook - www.facebook.com/PinnacleSports/ Soundcloud - @pinnacle-podcast Download the Pinnacle Live Scores app: www.pinnaclescores.com/ Gamble responsibly: bit.ly/3izDVaA

Tensions rise in east Asia as large-scale military drills kick off near South Korea's Jeju Island. Also in the programme: Nato's secretary general, Jens Stoltenberg, visits Oslo and South American leaders meet in Brasília to discuss relaunching the UNASUR bloc. Plus: food made using recycled breath could soon be on the menu for astronauts. See omnystudio.com/listener for privacy information.

In this episode, I discuss the impact Lucifer's Rebellion had on our world, and how Caligastia may play a continuing role today in sponsoring rampant evil. It's not an easy subject because man is certainly responsible for his own evil acts, but how does evil manifest? This is part of our discussion. Also, new DNA discoveries confirm Urantia Book teachings about early South American migration. --- Support this podcast: https://podcasters.spotify.com/pod/show/james-watkins/support

This week on Historia Obscura: how a South American dictator's relentless ambition led to the demise of more than half of his country's citizens. Special thanks to Patreon subscribers Barbara, Lisa Chase, and Tom! Subscribe to my Patreon at https://www.patreon.com/historiaobscura! --- Send in a voice message: https://podcasters.spotify.com/pod/show/historiaobscura/message

Paul Hawksbee and Andy Jacobs are joined in the pod by South American football expert Tim Vickery as well as co-host of The Sweeper Podcast Lee Wingate. Hosted on Acast. See acast.com/privacy for more information.

Today's Mystery: Steve goes to a South American country to find out who killed a man with papers identifying him as Steve Mitchell.Original Radio Broadcast Date: March 10, 1951Originated in HollywoodStars: Brian Donlevy as Steve Mitchell, Herb Butterfield as the Commissioner, Wally MaherSupport the show monthly at patreon.greatdetectives.netSupport the show on a one-time basis at http://support.greatdetectives.net.Mail a donation to: Adam Graham, PO Box 15913, Boise, Idaho 83715Take the listener survey at http://survey.greatdetectives.netGive us a call at 208-991-4783Follow us on Instagram at http://instagram.com/greatdetectivesFollow us on Twitter @radiodetectivesJoin us again tomorrow for another detective drama from the Golden Age of Radio.

This season of ATM concludes with special guest Viny Costa. Viny shares a little South American theology, the difference between communal and personal expressions of faith, and the book that he's read 15 times!

During this walk, we are BLESSED to be joined by our friends and colleagues in South America! Joining from Venezuela and Ecuador, we will be discussing sport and culture in the South American context. Discussion Points Sports agency culture in Venezuela and South America Managing an international event, such as the Oceanman open water swimming competitions Sport globalization on the South American continent Creating and sustaining global partnerships Virtual Exchange and its benefit for student and faculty learning Panelists: Pablo García Lawyer, International Agent (Venezuela )with BNM Ontier Sara Palacios and Diego Egas - Aguas Abiertas CEO and Race Director at Oceanman Ecuador USA + Ecuador - Building Bridges Across Cultures through Sports: A Global Classroom Collaboration Experience - Universidad San Francisco de Quito and the University of West Georgia (academic) Dr. Maria Dolores Brito-Rhor and Dr. Su Jara-Pazmino. This session would not have been possible without the support and leadership of Dr. E. Su Jara-Pazmino, Assistant Professor / Coordinator Master Program at University of West Georgia. Session was recorded as part of the 2023 Internationalization and Athletics Summit. --- Support this podcast: https://podcasters.spotify.com/pod/show/walkwithtfb/support

18th-century explorer Alexander Humboldt found the vestiges of a dead South American language in the most unusual host! Music from Fesliyan Studios Please support the show at www.patreon.com/historyobscura or at www.buymeacoffee.com/historyobscura Thank you!

In 1980, a group of 16 army sergeants, led by Dési Bouterse, seized power in the small South American country of Suriname, overthrowing the government in a swift and violent coup d'état. The coup came just five years after the country was granted independence from the Netherlands. The country's first president, Johan Ferrier, was forced to leave Suriname after the coup. Rosemarijn Hoefte, professor of the history of Suriname at the University of Amsterdam, and Johan Ferrier's daughter, Cynthia, have been sharing their memories of that time with Matt Pintus. (Photo: Johan Ferrier. Credit: Alamy)

This month on Episode 48 of Discover CircRes, host Cynthia St. Hilaire highlights three original research articles featured in the April 28th issue of Circulation Research. This Episode also includes a discussion between Dr Mina Chung, Dr DeLisa Fairweather and Dr Milka Koupenova, who all contributed to manuscripts to the May 12th Compendium on Covid-19 and the Cardiovascular System.     Article highlights:   Heijman, et al. Mechanisms of Enhanced SK-Channel Current in AF   Chen, et al. IL-37 Attenuates Platelet Activation   Enzan, et al. ZBP1 Protects Against Myocardial Inflammation   Compendium on Covid-19 and the Cardiovascular System.   Cindy St. Hilaire: Hi, and welcome to Discover CircRes, the podcast of the American Heart Association's journal, Circulation Research. I'm your host, Dr Cindy St. Hilaire, from the Vascular Medicine Institute at the University of Pittsburgh. Today, I'm going to be highlighting articles from our April 28th and May 12th issues of Circulation Research. I'm also going to have a chat with Dr Mina Chung, Dr DeLisa Fairweather and Dr Milka Koupenova, who all contributed to articles in the May 12th COVID Compendium. But before we have that interview, let's first talk about some highlights.   The first article I want to present is titled Enhanced Calcium-Dependent SK-Channel Gating and Membrane Trafficking in Human Atrial Fibrillation. This article is coming from the University of Essen by Heijman and Zhou, et al. Atrial fibrillation is one of the most common forms of heart arrhythmia in humans and is characterized by irregular, often rapid heartbeats that can cause palpitations, dizziness and extreme fatigue. Atrial fibrillation can increase a person's risk of heart failure, and though treatments exist such as beta blockers, blood thinners and antiarrhythmia medications, they can have limited efficacy and side effects. A new family of drugs in development are those blocking small-conductance calcium-activated potassium channels called SK channels, which exhibit increased activity in animal models of AF and suppression of which attenuates the arrhythmia. In humans however, the relationship between SK channels and atrial fibrillation is less clear, at least in terms of SK channel mRNA levels. Because mRNA might not reflect actual channel activity, this group looked at just that and they found indeed that channel activity was increased in cardiomyocytes from atrial fibrillation patients compared to those from controls even though the mRNA and protein levels themselves were similar. The altered currents were instead due to changes in SK channel trafficking and membrane targeting. By confirming that SK channels play a role in human atrial fibrillation, this work supports the pursuit of SK channel inhibitors as possible new atrial fibrillation treatments.   The next article I want to present is titled IL-37 Attenuates Platelet Activation and Thrombosis Through IL-1R8 Pathway. This article comes from Fudan University by Chen and Hong, et al. Thrombus formation followed by the rupture of a coronary plaque is a major pathophysiological step in the development of a myocardial infarction. Understanding the endogenous antithrombotic factors at play could provide insights and opportunities for developing treatments. With this in mind, Chen and Hong, et al. investigated the role of interleukin-1 receptor 8, or IL-1R8, which suppresses platelet aggregation in mice, and of IL-37, a newly discovered human interleukin that forms a complex with IL-1R8 and is found at increased levels in the blood of patients with myocardial infarction. Indeed, the amount of IL-37 in myocardial infarction patients negatively correlates with platelet aggregation. They also show that treatment of human platelets in vitro with IL-37 suppresses the cell's aggregation and does so in a concentration-dependent manner. Moreover, injection of the protein into the veins of mice inhibits thrombus development and better preserves heart function even after myocardial infarction. Such effects were not seen in mice lacking IL-1R8. This suggests IL-37's antithrombotic action depends on its interaction with the receptor. Together, the results suggest IL-37 could be developed as a antithrombotic agent for use in MI patients or indeed perhaps other thrombotic conditions.   The last article I want to present before our interview is titled ZBP1 Protects Against Mitochondrial DNA-Induced Myocardial Inflammation in Failing Hearts. This article is coming from Kyushu University and is by Enzan, et al. Myocardial inflammation is a key factor in the pathological progression of heart failure and occurs when damaged mitochondria within the stricken cardiomyocyte release their DNA, triggering an innate inflammatory reaction. In a variety of cells, DNA sensors such as Z-DNA-binding protein 1 or ZBP1 are responsible for such mitochondrial DNA-induced inflammation. In theory then, it's conceivable that therapeutic suppression of ZBP1 might reduce myocardial inflammation in heart failure and preserve function. But as Enzan and colleagues have now discovered to their surprise, mice lacking ZBP1 exhibited worse, not better heart inflammation and more failure after induced myocardial infarction. Indeed, the test animals' hearts had increased infiltration of immune cells, production of inflammatory cytokines and fibrosis together with decreased function compared with the hearts of mice with normal ZBP1 levels. Experiments in rodent cardiomyocytes further confirmed that loss of ZBP1 exacerbated mitochondrial DNA-induced inflammatory cytokine production while overexpression of ZBP1 had the opposite effect. While the reason behind ZBP1's opposing roles in different cells is not yet clear, the finding suggests that boosting ZBP1 activity in the heart might be a strategy for mitigating heart inflammation after infarction.   Cindy St. Hilaire:         The May 12th issue of Circulation Research is our COVID compendium, which consists of a series of 10 reviews on all angles of COVID-19 as it relates to cardiovascular health and disease. Today, three of the authors of the articles in this series are here with me. Dr Mina Chung is a professor of medicine at the Cleveland Clinic. She and Dr Tamanna Singh and their colleagues wrote the article, A Post Pandemic Enigma: The Cardiovascular Impact of Post-Acute Sequelae of SARS-CoV-2. Dr DeLisa Fairweather, professor of medicine, immunology and clinical and translational science at the Mayo Clinic, and she and her colleagues penned the article, COVID-19 Myocarditis and Pericarditis. Dr Milka Koupenova is an assistant professor of medicine at the UMass Chan School of Medical and she led the group writing the article, Platelets and SARS-CoV-2 During COVID-19: Immunity, Thrombosis, and Beyond. Thank you all for joining me today.   DeLisa Fairweather:    Thank you so much for having us.   Mina Chung:   Thank you.   Milka Koupenova:       Thank you for having us, Cindy.   Cindy St. Hilaire:         In addition to these three articles, we have another seven that are on all different aspects of COVID. Dr Messinger's group wrote the article, Interaction of COVID-19 With Common Cardiovascular Disorders. Emily Tsai covered cell-specific mechanisms in the heart of COVID-19 patients. Mark Chappell and colleagues wrote about the renin-angiotensin system and sex differences in COVID-19. Michael Bristow covered vaccination-associated myocarditis and myocardial injury. Jow Loacalzo and colleagues covered repurposing drugs for the treatment of COVID-19 and its cardiovascular manifestations. Dr Stephen Holby covered multimodality cardiac imaging in COVID, and Arun Sharma covered microfluidic organ chips in stem cell models in the fight against COVID-19.   Cindy St. Hilaire          As of today, worldwide, there have been over six hundred million individuals infected with the virus and more than six and a half million have died from COVID-19. In the US, we are about a sixth of all of those deaths. Obviously now we're in 2023, the numbers of individuals getting infected and dying are much, much lower. As my husband read to me this morning, one doctor in Boston was quoted saying, "People are still getting wicked sick." In 75% of deaths, people have had underlying conditions and cardiovascular disease is found in about 60% of all those deaths. In the introduction to the compendium, you mentioned that the remarkable COVID-19 rapid response initiative released by the AHA, which again is the parent organization of Circ Research and this podcast, if I were to guess when that rapid response initiative started, I would've guessed well into the pandemic, but it was actually March 26th, 2020. I know in Pittsburgh, our labs have barely shut down. So how soon after we knew of SARS-CoV-2 and COVID, how soon after that did we know that there were cardiovascular complications?   Mina Chung:               I think we saw cardiovascular complications happening pretty early. We saw troponin increases very early. It was really amazing what AHA did in terms of this rapid response grant mechanism. You mentioned that the RFA was announced, first of all, putting it together by March 26th when we were just shutting down in March was pretty incredible to get even the RFA out. Then the grants were supposed to be submitted by April 6th and there were 750 grants that were put together and submitted. They were all reviewed within 10 days from 150 volunteer reviewers. The notices were distributed April 23rd, less than a month out.   Cindy St. Hilaire:         Amazing.   Mina Chung:               So this is an amazing, you're right, paradigm for grant requests and submissions and reviews.   DeLisa Fairweather:    For myocarditis, reports of that occurred almost immediately coming out of China, so it was incredibly rapid.   Cindy St. Hilaire:         Yeah, and that was a perfect lead up to my next question. Was myocarditis, I guess, the first link or the first clue that this was not just going to be a respiratory infection?   DeLisa Fairweather:    I think myocarditis appearing very early, especially it has a history both of being induced by viruses, but being strongly an autoimmune disease, the combination of both of those, I think, started to hint that something different was going to happen, although a lot of people probably didn't realize the significance of that right away.   Cindy St. Hilaire:         What other disease states, I guess I'm thinking viruses, but anything, what causes myocarditis and pericarditis normally and how unique is it that we are seeing this as a sequelae of COVID?   DeLisa Fairweather:    I think it's not surprising that we find it. Viruses around the world are the primary cause of myocarditis, although in South America, it's the parasite Trypanosoma cruzi. Really, many viruses that also we think target mitochondria, including SARS-CoV-2, have an important role in driving myocarditis. Also, we know that SARS-CoV-1 and MERS also reported myocarditis in those previous infections. We knew about it beforehand that they could cause myocarditis.   Cindy St. Hilaire:        Is it presenting differently in a COVID patient than say those South American patients with the... I forget the name of the organism you said, but does it come quickly or get worse quickly or is it all once you get it, it's the same progression?   DeLisa Fairweather:    Yeah. That's a good question. Basically, what we find is that no matter what the viral infection is, that myocarditis really appears for signs and symptoms and how we treat it identically and we see that with COVID-19. So that really isn't any different.   Cindy St. Hilaire:         Another huge observation that we noticed in COVID-19 patients, which was the increased risk of thrombic outcomes in the patients. Dr Koupenova, Milka, you are a world expert in platelets and viruses and so you and your team were leading the writing of that article. My guess is knowing what you know about platelets and viruses, this wasn't so surprising to you, but could you at least tell us the state of the field in terms of what we knew about viruses and platelets before COVID, before Feb 2020?   Milka Koupenova:       Before Feb 2020, we actually knew that influenza gets inside in platelets. It leads to not directly prothrombotic events, but it would lead to release of complement 3 from them. That complement 3 would actually increase the immunothrombosis by pushing neutrophils to release their DNA, forming aggregates. In cases when you have compromised endothelium and people with underlying conditions, you would expect certain thrombotic outcomes. That, we actually published 2019 and then 2020 hit. The difference between influenza and SARS-CoV-2, they're different viruses. They carry their genome in a different RNA strand. I remember thinking perhaps viruses are getting inside in platelets, but perhaps they do not. So we went through surprising discoveries that it seemed like it is another RNA virus. It also got into platelets. It was a bit hard to tweak things surrounding BSL-3 to tell you if the response was the same. It is still not very clear how much SARS or rather what receptor, particularly when it gets inside would induce an immune response. There are some literature showing the MDA5, but not for sure, may be responsible. But what we found is that once it gets in platelets, it just induces this profound activation of programmed cell death pathways and release of extracellular vesicles and all these prothrombotic, procoagulant form of content that can induce damage around, because platelets are everywhere. So that how it started in 2019 and surprisingly progressed to 2021 or 2020 without the plan of really studying this virus.   Cindy St. Hilaire:         How similar and how different is what you observe in platelets infected, obviously in the lab, so I know it's not exactly the same, but how similar and how different is it between the flu? Do you know all the differences yet?   Milka Koupenova:       No offense here, they don't get infected.   Cindy St. Hilaire:         Okay.   Milka Koupenova:       Done the proper research. The virus does not impact platelets, but induces the response.   Cindy St. Hilaire:         Okay.   Milka Koupenova:       That goes back to sensing mechanism. Thank goodness platelets don't get infected because we would be in a particularly bad situation, but they remove the infectious virus from the plasma from what we can see with function.   Cindy St. Hilaire:         Got it. So they're helping the cleanup process and in that cleaning up is where the virus within them activates. That is a really complicated mechanism.    Milka Koupenova:       Oh, they're sensing it in some form to alert the environment. It's hard to say how similar and how different they are unless you study them hint by hint next to each other. All I can tell is that particularly with SARS-C, you definitely see a lot more various kinds of extracellular vesicles coming out of them that you don't see the same way or rather through the same proportion with influenza. But what that means in how platelet activates the immune system with one versus the other, and that goes back to the prothrombotic mechanisms. That is exactly what needs to be studied and that was the call for this COVID compendium is to point out how much we have done as a team. As scientists who put heads together, as Mina said, superfast response, it's an amazing going back and looking at what happened to think of what we achieved. There is so much more, so much more that we do not understand how one contributes to all of these profound responses in the organs themselves, such as myocarditis. We see it's important and that will be the problem that we're dealing from here on trying to figure it out and then long COVID, right?   Cindy St. Hilaire:         Yeah. Related to what you just said about the mechanism, this cleanup by the platelets or the act of cleaning up helps trigger their activation, is that partly why the antiplatelet and anticoagulant therapies failed in patients? Can you speculate on that? I know the jury's still out and there's a lot of work to be done, but is that part of why those therapies weren't beneficial?   Milka Koupenova:       The answer to that in my personally biased opinion is yes. Clearly, the antiplatelet therapies couldn't really control the classical activation of a platelet. So what I think we need to do from here on is to look at things that we don't understand that non-classically contribute to the thrombotic response downstream. If we manage to control the immune response in some way or the inflammation of the infection or how a platelet responds to a virus, then perhaps we can ameliorate a little bit of the downstream prothrombotic effect. So it's a lot more for us to trickle down and to understand in my personal opinion.   DeLisa Fairweather:    There is one thing that was really remarkable to me in hearing your experience, Milka, is that I had developed an autoimmune viral model of myocarditis in mice during my postdoc. So I've been studying that for the last 20 years. What is unique about that model is rather than using an adjuvant, we use a mild viral infection so it doesn't take very much virus at all going to the heart to induce it. I also, more recently, started studying extracellular vesicles really as a therapy, and in doing that, inadvertently found out that actually, the model that I'd created where we passage the virus through the heart to induce this autoimmune model, we were actually injecting extracellular vesicles into the mice and that's what was really driving the disease. This is really brought out. So from early days, I did my postdoc with Dr Noel Rose. If you've heard of him, he came up with the idea of autoimmune disease in the '50s. We had always, in that environment, really believed that viruses were triggering autoimmune disease and yet it took COVID before we could really prove that because no one could identify them. Here we have an example and I think the incidence rates with COVID were so high for myocarditis because for the first time, we had distinguished symptoms of patients going to the doctor right at the beginning of their infection having an actual test to examine the virus, knowing whether it's present or not, whether PCR or antibody test, and then being able to see when myocarditis happened.   Cindy St. Hilaire:         Yeah. I think one thing we can all appreciate now is just some of the basic biology we've learned on the backend of this. Actually, those last comments really led well to the article that your team led, Dr Chung, about what we call long COVID, which I guess I didn't realize has an actual name, post-acute sequelae of SARS-CoV-2 or PASC is the now more formal name for long COVID. But what is it? We hinted at it that there's these bits about autoimmune and things like that. What counts as long COVID?   Mina Chung:   Yeah. Our article was led by Tamanna Singh. She did a fantastic job of putting this together. We've had, and others, theorized that the huge palette of symptoms that you can experience post-COVID, they can affect all these organ systems with brain fog, these atypical chest pains, postural orthostatic tachycardia, a lot of palpitations, atrial fibrillation, many weakness and fatigue. To us, really, you can get GI symptoms. We've been very interested in, is this an autoimmune phenomenon directed against nerves and all those things. It's also very interesting because many of the non-COVID syndromes that existed pre-COVID like POTS and chronic fatigue syndrome and a lot of other syndromes are associated with autoantibodies. So that is a very interesting area to explore. Is there a persistence of viral fragments. Is there autoimmunity? Is it also a component of persistence of the damage from the initial infection? So it's an area that still needs a lot of work and a lot of work is going into it, but this is like a post or inter pandemic of itself, so hopefully we'll get more insights into that.   Cindy St. Hilaire:         Yeah, it's really interesting. I have a friend who has very debilitating long COVID and one of her doctors had said, "If I didn't know any better, I would just describe this as a autoimmune type X." What do we know, I guess, about the current hypothesis of the pathogenesis of PASC? Are there any prevailing theories right now as to why it's occurring? Is the virus still active or is it these domino effects that are leading to multi-organ collapse of some sort?   Mina Chung:   Yeah. In some people, persistent viral particles can be identified for months, but whether or not that's what's triggering it, it's hard to know. We see more autoimmune disease that's been reported and various antibodies being reported. So those are clearly processes to be investigated. The microthrombosis is still up there in terms of potentially playing a role in long COVID.   Milka Koupenova:       Mina, you probably know better because you see patients, but to all I have been exposed to, long COVID does not really have a homogeneous symptom presentation and then a few theories as to what may be going on in these patients. Not everybody has a microthrombosis. Not everybody have a D-dimer elevated, but some people do. Some people have, as you pointed out, these spectacularly profound brain fog. People can't function. It's probably your friend, Cindy, right?   Cindy St. Hilaire:         Yeah.   Milka Koupenova:       So one of the theories that I have been, from a viral perspective, very interested in is that a lot of the symptoms in certain individuals such as fatigue, brain fog, sensitivity to light and skin can very well be explained by a flare-up of Epstein-Barr virus that may be what SARS-CoV-2 somehow is inducing. I don't know, DeLisa, what your experience with long COVID is as a scientist. I hope only. But I would like to hear your perspective too because it's so heterogeneous and it is amazing what happens.   DeLisa Fairweather:    I have a very interesting perspective from a number of different directions. One, as I mentioned before, my long history with Dr Rose and I've written many articles theorizing how viruses could cause autoimmune disease. This has grown and really, I think this has been extremely revealing during COVID for many of those theories. One thing that I write about in the review for this article is that mast cells, from all the research I've done with myocarditis in our model, mast cells are central to what is driving everything. We show they're the first innate immune cell acting as an antigen-presenting cell, completely driving the response in a susceptible pattern. One of the things that's very important in autoimmune disease is both sex and race. I'd say one of the big weaknesses we have in myocarditis pre-COVID and post-COVID has been ignoring what's going on with race. In the United States, myocarditis is 90%, 95% white men that are under 50 years of age and most of the cases are under 40 or some of the ones really associated with sudden cardiac death are under 30. So it's very specific. I've been studying sex and race differences and we see those exact differences in our animal models. In animal models, whether you're susceptible or not depends on how many mast cells you have. Well, I've proposed from the beginning, looking, I've written a lot of different sex difference reviews looking at viruses and autoimmune disease with different autoimmune diseases and hypothesizing and really seeing that mast cells do a lot of the things we're talking about. They have all of the receptors, the whole group of them that have been related to SARS-CoV-2 so they can be activated or stimulated by the virus itself. They act as a antigen-presenting cell. They're critical in the complement pathway as well as macrophages. We see the dominant immune phenotype really being macrophages. Mast cells just are usually not counted anywhere. And of course, these receptors, a lot of them have to do with enzymes and things that are all related to mast cells pathways. Then how they activate the immune response and lead it towards the pathway that leads to chronic autoimmune disease with increased autoantibodies in females, mast cells are very different by sex. This has to do also when we talked in the Review about myocarditis and pericarditis. It's both those appearing. Although clinically, we have really boxed them as separate things, because there is some definite clinical pericarditis phenotypes that are different, myocarditis in animal models is always myopericarditis. It always then, in that outer pericardial areas where mast cells sit, they sit around the vascular area in most concentrated. So when they degranulate, we see inflammation coming in the vessel, but really concentrated with fibrosis there and along the pericardium. So that's very typical of what's going on. When we shift anything that shifts that, it changes whether you have more pericarditis or less pericarditis and the vascular inflammation by altering anything that affects the mast cells. I talk a little bit about in the review, I think there's only been a few recent things looking at it in COVID, but I think mast cells and certain susceptibility to autoimmune diseases that occur more often in women can really predispose.We need to pay more attention to mast cells and what they might indicate for all these pathways.   Milka Koupenova:       I think we should study the platelet mast cell access at this point.   DeLisa Fairweather:    Yes.   Milka Koupenova:       Because as you're talking about these sex differences, which is spectacular, these things to me are so mind-boggling how one, the infection itself would be more prevalent in men, but then long COVID is more prevalent in women. All of these things and why we understand so very little, what we found about a few years ago in the Framingham Heart Study in the platelets from those people is that all toll-like receptors are expressed at the higher level in women and they associate with different things between men and female. For instance, toll-like receptors in women will associate more with a prothrombotic response while in male with pro-inflammatory response. I think they grossly underestimate the amount of our sex differences from cell to cell.   DeLisa Fairweather:    It is, yeah.   Mina Chung:   One other thing that I learned about the sex differences from this compendium is Mark Chappell also notes, you mentioned TLR and TLR7 and ACE2 are X chromosome in an area that he says escapes X-linked inactivation. So it could very well be involved in further.   DeLisa Fairweather: Further, yeah. And ACE2 is expressed more highly in male cells for what's been researched because of the sex difference in COVID, both the COVID infection   Cindy St. Hilaire:         So a variety of organ systems are impacted in patients with PASC, also referred to as long COVID, the lungs, the heart, the pancreas, the GI system, pretty much any system, the brain, nervous system. We've just been talking about the mast cell impact. I was really thinking in my head, well, the one thing that connects all of it is the vasculature. I'm a vascular biologist, so I have certain biases, I'm sure, but how much of the sequelae that we see is a function of vascular phenotypes?       Milka Koupenova:       I do think the vasculature is super important. It's clear that not all endothelial cells, for instance, will pick up the virus and respond to it. That's why you have this patchy breakage when you look at autopsies. Hence, platelets will respond according to what's local. That's why you find these micro thrombotic events at certain places. Why does it happen in each organ? How does the virus get to each organ to respond? Or is it just inflammation, but why is it in specific places? That's what we don't understand. That's where we need to go. Perhaps, as DeLisa points out, perhaps it's a lot more complicated than how we traditionally think of thrombosis. Actually, my personal bias, again 100% sure that it is a lot more complicated than the traditional mechanisms that we have understood, and that's where the immune system comes and autoimmunity perhaps stems from and they probably speak to each other, right? It's not just one thing.   DeLisa Fairweather:    Yeah. I think really, EVs are bringing lots of understanding. A lot of things we used to just think were maybe free-floating and the serum are inside EVs. I think that the immune response is perhaps even more specific than we ever thought and more regulated than we ever understood.   When an EV comes through a cardiomyocyte, whether it's from the mitochondria or through a lysosome, is part of what goes into its outer membrane, something that tells the immune system that that came from the heart, so it knows to go. This will solve a lot of our questions with autoimmune disease if it's very specific like that. It doesn't just have to be the release of free-floating cardiac myosin. We know cardiac myosin is the driver of the autoimmune response in myocarditis, but they're probably  much more fine-tuned.   Cindy St. Hilaire:         Yeah. I just would love to end with hearing from each of you. You each have your own domain of specialty. If I gave you a massive pot of money, what would be the question you would want to tackle? What's the gap you would love to answer?   Milka Koupenova:       We still don't understand specifically what kind of vesicles are coming out, what are their contents in addition to those vesicles. We don't understand. When it comes to platelets, what comes from their granules? We see these breakages of the membrane. Those are non-granule proteins, and non-granule proteins, they serve as dangerous associated molecular pattern signals and can be profoundly inflammatory to the surrounding environment, can be procoagulant. What are those? How are they affecting the surrounding environment? Ultimately, why is there a microthrombi? Why is there not a profound thrombosis everywhere? Thank goodness there isn't, but why isn't? That's what I would do with my money.   DeLisa Fairweather:    I think I would do something very similar. All of our research in our animal model, on the one side, we are looking in this viral myocarditis animal model and finding the EVs that come from that are driving myocarditis. On the other hand, we're using EVs that come from healthy human plasma or fat, and we're seeing a profound downregulation of everything if you give it early and we're trying to see how late you can give it and still get an effect. So looking at those and really understanding the components in the context of COVID and COVID vaccines to understand those components, I really think that's the future of where we're going to find what's causing disease and also how we can find therapies. They may be able to reverse this.   Mina Chung:   Yeah, I'm interested very much in the autoimmunity and the autoantibodies that are    and how they may react with those microthrombi. Perhaps there's autoantibodies within a lot of that material. We're looking at using human and pluripotent stem cell-derived cell models to study the effects of those. That is what I would use our money for.   Cindy St. Hilaire:        Well, Dr Mina Chung, Dr DeLisa Fairweather, Dr Milka Koupenova, thank you all so much for joining me today and talking about not only the articles that you wrote and with your colleagues, but also other articles in this amazing compendium. I do think this is one of the first all-encompassing compendiums or group of articles that focus specifically on COVID and cardiovascular disease. So thank you all so much.   Mina Chung:   Thank you.   DeLisa Fairweather:    Thank you.   Milka Koupenova:       You're welcome.   Cindy St. Hilaire:         That's it for highlights from the April 28th and May 12th issues of Circulation Research. Thank you for listening. Please check out the CircRes Facebook page and follow us on Twitter and Instagram with the handle @circres and #DiscoverCircRes. Thank you to our guests, Dr Mina Chung, Dr DeLisa Fairweather and Dr Milka Koupenova. This podcast is produced by Ishara Ratnayaka, edited by Melissa Stoner and supported by the editorial team of Circulation Research. Some of the copy text for the highlighted articles is provided by Ruth Williams. I'm your host, Dr Cindy St. Hilaire, and this is Discover CircRes, your on-the-go source for the most exciting discoveries in basic cardiovascular research. This program is copyright of the American Heart Association 2023. The opinions expressed by speakers in this podcast are their own and not necessarily those of the editors or of the American Heart Association. For more information, visit ahajournals.org.    

Gripping legal procedural ARGENTINA, 1985 continues the Dads education in the South American countries cinema following our earlier viewing of THE SECRET IN THEIR EYES and this shares some similarities with that dazzling crime drama not least of which is star Ricardo Darin. Public prosecutor Julio César Strassera (Darin) reluctantly finds himself making the government's case against the former leaders of the military junta for crimes against humanity, as Argentina's nascent democratic government struggles to establish itself.We love to hear from our listeners! By which I mean we tolerate it. If it hasn't been completely destroyed yet you can usually find us on twitter @dads_film, on Facebook Bad Dads Film Review, on email at baddadsjsy@gmail.com or on our website baddadsfilm.com. Until next time, we remain... Bad Dads

How Max From Argentina Overcame His Struggles and Became an English Teacher

Weird things happen when you're an investigative reporter trying to cover an international oil giant like ExxonMobil. Your plane tickets are mysteriously canceled, your hotel room gets broken into, and the local reporter that you've hired is offered a lucrative job to work on something else. In this special bonus episode for War on Cars Patreon subscribers, investigative journalist and podcaster Amy Westervelt tells us what it was like to report and produce the new season of her podcast, Drilled. It's called "Light Sweet Crude." In it, she takes us to the tiny South American nation Guyana where, in 2015, ExxonMobil discovered one of the world's largest off-shore oil reserves. Seemingly overnight, Guyana began transforming from an international environmental leader and model of sustainable development to one of the world's fastest growing petrostates. ***This is a preview of a Patreon-exclusive, ad-free bonus episode. For complete access to this and all of our bonus content, become a Patreon supporter of The War on Cars.***

THIS WEEK on the GWA Podcast, I interview one of the most renowned artists living today, Adriana Varejão Best known for her sculptural, almost architectural, paintings that extend far beyond the frame, Varejão has tackled themes of Brazilian cultural identity, challenged ideas of modern monuments, and in her art exposes colonial truths through traditional processes. Drawing upon the visual language of the European Baroque, Chinese Song ceramics as well as Brazilian and other South American traditions – just as she once said: interest lies in the interactions between different latitudes of the world. At once gory and theatrical, Varejão's work is all about what lies under the surface – literally – under the layers of canvas or plaster but also metaphorically, asking whose stories are being hidden, what violence is being covered up. She has exhibited all over the world with major exhibitions in Sao Paulo, Rio de Janeiro, at the ICA in Boston, and in 2016 designed the Brazilian Olympic Aquatics Stadium. Today, Varejão's practice continues to break ground in how we interpret cross-global intersections and ideas. Follow us: Katy Hessel: @thegreatwomenartists / @katy.hessel Sound editing by Mikaela Carmichael Artwork by @thisisaliceskinner Music by Ben Wetherfield https://www.thegreatwomenartists.com/ THIS EPISODE IS GENEROUSLY SUPPORTED BY OCULA: https://ocula.com/

Southeast Asia and South America are regions made up of largely illiberal states lacking stabilizing great powers or collective identities. But despite persistent territorial disputes, regime instability, and interstate rivalries, both regions have avoided large-scale war for decades. What accounts for the lack of war in these regions, and importantly, how are conflicts managed? In Practicing Peace: Conflict Management in Southeast Asia and South America (Oxford University Press, 2022), Dr. Aarie Glas offers a comparative regional perspective on conflict management and diplomacy in Southeast Asia and South America. Dr. Glas finds that regional interstate relations are shaped by particular habitual dispositions—discrete sets of processual and substantive qualities of relations understood and enacted by diplomatic communities of practice. Different habitual dispositions in each case shape conflict management and regionalism in important ways, and lead to a tolerance of limited regional violence. Dr. Glas expands on new developments in social International Relations theory to develop a practice-oriented and interpretive account of regional relations and explores the existence of habitual dispositions across crucial cases of regional conflict management, including the Southeast Asian response to the Preah Vihear dispute in 2011 and the South American response to the Cenepa conflict in 1995. Drawing on novel research methods and detailed interviews with regional practitioners, Practicing Peace challenges existing scholarly claims of peace in Southeast Asia and South America. Instead, Dr. Glas argues that officials successfully manage pervasive conflict short of war in both regions. He provides an in-depth look into how diplomacy unfolds and peace is practiced within diplomatic communities, from government actors to organizational officials, as they attempt to respond to and resolve territorial disputes. This interview was conducted by Dr. Miranda Melcher whose doctoral work focused on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network

Southeast Asia and South America are regions made up of largely illiberal states lacking stabilizing great powers or collective identities. But despite persistent territorial disputes, regime instability, and interstate rivalries, both regions have avoided large-scale war for decades. What accounts for the lack of war in these regions, and importantly, how are conflicts managed? In Practicing Peace: Conflict Management in Southeast Asia and South America (Oxford University Press, 2022), Dr. Aarie Glas offers a comparative regional perspective on conflict management and diplomacy in Southeast Asia and South America. Dr. Glas finds that regional interstate relations are shaped by particular habitual dispositions—discrete sets of processual and substantive qualities of relations understood and enacted by diplomatic communities of practice. Different habitual dispositions in each case shape conflict management and regionalism in important ways, and lead to a tolerance of limited regional violence. Dr. Glas expands on new developments in social International Relations theory to develop a practice-oriented and interpretive account of regional relations and explores the existence of habitual dispositions across crucial cases of regional conflict management, including the Southeast Asian response to the Preah Vihear dispute in 2011 and the South American response to the Cenepa conflict in 1995. Drawing on novel research methods and detailed interviews with regional practitioners, Practicing Peace challenges existing scholarly claims of peace in Southeast Asia and South America. Instead, Dr. Glas argues that officials successfully manage pervasive conflict short of war in both regions. He provides an in-depth look into how diplomacy unfolds and peace is practiced within diplomatic communities, from government actors to organizational officials, as they attempt to respond to and resolve territorial disputes. This interview was conducted by Dr. Miranda Melcher whose doctoral work focused on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/latin-american-studies

Southeast Asia and South America are regions made up of largely illiberal states lacking stabilizing great powers or collective identities. But despite persistent territorial disputes, regime instability, and interstate rivalries, both regions have avoided large-scale war for decades. What accounts for the lack of war in these regions, and importantly, how are conflicts managed? In Practicing Peace: Conflict Management in Southeast Asia and South America (Oxford University Press, 2022), Dr. Aarie Glas offers a comparative regional perspective on conflict management and diplomacy in Southeast Asia and South America. Dr. Glas finds that regional interstate relations are shaped by particular habitual dispositions—discrete sets of processual and substantive qualities of relations understood and enacted by diplomatic communities of practice. Different habitual dispositions in each case shape conflict management and regionalism in important ways, and lead to a tolerance of limited regional violence. Dr. Glas expands on new developments in social International Relations theory to develop a practice-oriented and interpretive account of regional relations and explores the existence of habitual dispositions across crucial cases of regional conflict management, including the Southeast Asian response to the Preah Vihear dispute in 2011 and the South American response to the Cenepa conflict in 1995. Drawing on novel research methods and detailed interviews with regional practitioners, Practicing Peace challenges existing scholarly claims of peace in Southeast Asia and South America. Instead, Dr. Glas argues that officials successfully manage pervasive conflict short of war in both regions. He provides an in-depth look into how diplomacy unfolds and peace is practiced within diplomatic communities, from government actors to organizational officials, as they attempt to respond to and resolve territorial disputes. This interview was conducted by Dr. Miranda Melcher whose doctoral work focused on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/southeast-asian-studies

Southeast Asia and South America are regions made up of largely illiberal states lacking stabilizing great powers or collective identities. But despite persistent territorial disputes, regime instability, and interstate rivalries, both regions have avoided large-scale war for decades. What accounts for the lack of war in these regions, and importantly, how are conflicts managed? In Practicing Peace: Conflict Management in Southeast Asia and South America (Oxford University Press, 2022), Dr. Aarie Glas offers a comparative regional perspective on conflict management and diplomacy in Southeast Asia and South America. Dr. Glas finds that regional interstate relations are shaped by particular habitual dispositions—discrete sets of processual and substantive qualities of relations understood and enacted by diplomatic communities of practice. Different habitual dispositions in each case shape conflict management and regionalism in important ways, and lead to a tolerance of limited regional violence. Dr. Glas expands on new developments in social International Relations theory to develop a practice-oriented and interpretive account of regional relations and explores the existence of habitual dispositions across crucial cases of regional conflict management, including the Southeast Asian response to the Preah Vihear dispute in 2011 and the South American response to the Cenepa conflict in 1995. Drawing on novel research methods and detailed interviews with regional practitioners, Practicing Peace challenges existing scholarly claims of peace in Southeast Asia and South America. Instead, Dr. Glas argues that officials successfully manage pervasive conflict short of war in both regions. He provides an in-depth look into how diplomacy unfolds and peace is practiced within diplomatic communities, from government actors to organizational officials, as they attempt to respond to and resolve territorial disputes. This interview was conducted by Dr. Miranda Melcher whose doctoral work focused on post-conflict military integration, understanding treaty negotiation and implementation in civil war contexts, with qualitative analysis of the Angolan and Mozambican civil wars. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/world-affairs

Quizmasters Lee and Marc meet with Tim & Joee for a trivia quiz with topics including NHL, 80s Movies, Dinosaurs, 2000's R&B, Movies, Beer, Birds, Hats and more! Round One NHL - First established in 1970, which NHL team out of New York is named after a type of weapon and is the oldest active team in the NHL to have never won a Stanley Cup? BALLOONING - The International Balloon Fiesta is the world's largest air balloon festival and is located in what Southwestern U.S. city? 80s MOVIES - While the shark from Jaws did not have an official name, it was named on set by crew after director Steven Spielberg's lawyer at the time, whose first name was what? DINOSAURS - The 1993 film Jurassic Park can be forgiven for its misrepresentation of which dinosaur due the fact that definitive evidence of its feathered appendages was not unearthed until 1998? 2000's R&B - Beginning with 2001's "U Remind Me," which Atlanta-based male R&B artist had more #1 hits than any other artist or group on Billboard's R&B charts in the 2000's decade? ETYMOLOGY - Nicholas Rowe's 1703 play The Fair Penitent originated what character whose name has since referred to a seducer of women? Round Two MOVIE CASTS - Beaumont Livingston, Lewis Gara and Ordell Robbie are characters in which Quentin Tarantino movie? BIOCHEMISTRY - In biochemistry, what is the term for a protein that acts as a catalyst for accelerating chemical reactions? BEER - The development and refinement of the types of beer that we enjoy today is credited to several parts of Europe, but beer was first made by the Sumerians around 4000 B.C. in a region of the middle East that is modern day Iraq. What was this region called? BIRDS - Precocial birds such as chickens and altricial birds such as robins are placed into these categories based on what reproductive adaptation? U.S. POLITICS - What Secretary of State in the 21st century kept a Cleveland Browns helmet in their office? ANIMALS - What kind of South American freshwater snail can be found in Florida, Hawaii and Southeast Asia and is known for its long eye-stalks and for laying its eggs above the waterline? Rate My Question LITERATURE & MUSIC - When singing the song's title in the chorus of Starman, David Bowie performs an octave leap mirroring the journey of the song's protagonist with what famous literary character? Final Questions ENDANGERED ANIMALS - Crysomallon Squamiferum, aka the Sea Pangolin or Volcano Snail, which is only found in deep sea hydrothermal vents has adapted to its extreme environment by adding what element, the fifth most common on Earth, to its armored shell? U.S. STATE POPULATIONS - Known for its impressive landscape and natural beauty, which state has the smallest population in the U.S.? HATS - What kind of close-fitting bell-shaped hat is often made of felt and was most-popular amongst women in the early 20th century? MOVIES - What 2010 movie, directed by Danny Boyle, was nominated for 6 Academy Awards including Best Actor and Best Picture? Upcoming LIVE Know Nonsense Trivia Challenges May 17th, 2023 - Point Ybel Brewing Co. - 7:30 pm EST May 18th, 2023 - Ollie's Pub Records and Beer - 7:30 pm EST May 27th, 2023 - Gaming Trivia - Ollie's Pub - 6:00 pm EST June 3rd, 2023 - Trashy TV Trivia - Ollie's Pub - 6:00 pm EST You can find out more information about that and all of our live events online at KnowNonsenseTrivia.com All of the Know Nonsense events are free to play and you can win prizes after every round. Thank you Thanks to our supporters on Patreon. Thank you, Quizdaddies – Gil, Tim, Tommy, Adam, Brandon, Blake, Spencer, Rick G Thank you, Team Captains – Kristin & Fletcher, Aaron, Matthew, David Holbrook, Lydia, Skyler, Hayden Thank you, Proverbial Lightkeepers – Elyse, Kaitlynn, Frank, Trent, Nina, Justin, Katie, Ryan, Robb, Captain Nick, Grant, Ian, Tim Gomez, Rachael, Moo, Rikki, Nabeel, Jon Lewis, Adam, Lisa, Spencer, Hank, Justin P., Cooper, Sarah, Karly, Lucas, Mike K., Cole, Adam, Caitlyn H, Sam, Spencer, Stephen, Cameron, Clay, JB, Joshua, James, Paul, Marit, JV, Jesse, Thank you, Rumplesnailtskins – Mike J., Mike C., Efren, Steven, Kenya, Dallas, Issa, Paige, Allison, Kevin & Sara, Alex, Loren, MJ, HBomb, Aaron, Laurel, FoxenV, Sarah, Edsicalz, Megan, brandon, Chris, Alec, Sai, Tim, Andrea, Ian, Aunt Kiki, Clay, Littlestoflambs, Seth, Bill, Marc P., Holgast, Nora, Joe, Emily, Andrew H., Joe, Cara, Nathan, Joey, Brian K., Zoe, Kristy, Kinkalot If you'd like to support the podcast and gain access to bonus content, please visit http://theknowno.com and click "Support." Special Guests: Joee Patterson and Tim Gomez.

Central and South American migrants continue to surge the border since the expiration of Title 42 last night at midnight. Howie discusses the pure idiocy of the Democrat Party--that is, unless their plan is the destruction of society. Tune in for Howie's conversations with callers who are fed up with Biden's nonsense.

Huddersfield's finest - Mr Luke Butterworth drops in for a chat. Lots of topics and locations broached, from championship footy to South American road trips, debt collecting, Coldpl@y and insightful squash coaching advice.

Environment writer Michael Booth talks with new Colorado Sun international journalism fellow Manuel Novik about the biggest environmental issues in Ecuador, with a South American travel tips bonus.See omnystudio.com/listener for privacy information.

Danny Paradise Part 2 Teacher to the Stars & Creator of Music ( www.dannyparadise.com @danny_paradise108) Travelling & Sharing yoga | Doorways opening to countries | Teaching Sting, Madonna & other celebrities | Freedom Fighters | Love Will Rescue You | Children of The Forest | A Song For a Revolution | Ashtanga is not just for kids (more about Danny below)  ******************************************* This episode is sponsored by Momence, the booking system we use and highly recommend. For our online, in-person and hybrid classes and events. There are packages to fit self-employed teachers to multi-site studios. With Momence, you can: ·  ·        Manage your class and workshop schedule ·       Organize your appointment types and availability ·       Create marketing and win-back campaigns ·       Organize your on-demand videos and courses ·       See exactly how your business is doing through insightful reporting. ·       Have customers self-check-in via kiosks ·       Sell products and services with a fully integrated point of sale  With live support by chat, phone and email Momence is easy to use for yourself and your customers.  2 MONTHS FREE TRAIL: for more information click on the link https://www.keenonyoga.com/momence/ or book a demo and quote “Keen on Yoga”   ************************************************************* Support Us Subscribe, like, comment and share with your friends Donate: https://keenonyoga.com/donate/ Buy us a coffee: https://www.buymeacoffee.com/infoRf Become a Patron:  https://keenonyoga.com/membership/  Exclusive content, yoga & lifestyle tips, live Zoom meet-ups & more.  €10 per month, cancel at any time. Connect With Keen On Yoga Instagram Keen on Yoga: https://www.instagram.com/keen_on_yoga/ Instagram Adam Keen: https://www.instagram.com/adam_keen_ashtanga/ Website: https://keenonyoga.com/  __________________________________________________________________ Danny has been practising Ashtanga Yoga since May 1976 and teaching publicly (and occasionally privately) worldwide since 1979. He teaches all levels of students and teachers and was in one of the earliest groups of Westerners to learn all the classical sequences of Ashtanga Yoga. His first teachers were David Williams and Nancy Gilgoff. David was the first western Ashtanga adept. He began teaching with David Williams in 1979 and was asked to assist him at that time. Danny introduces the forms to beginning students, experienced, advanced practitioners, and teachers. Many people he has taught are now teaching others and have their own schools. He also introduced the Ashtanga forms to many people who were Yoga teachers in other traditions and styles. He's taught numerous well-known artists, musicians, dancers, and sports champions and studied with K. Pattabhi Jois in 1978 in Hawaii and 1980 in Hawaii in the USA. This included K.P. Jois' first advanced series of public classes in 1980 which were in Maui, Hawaii. He's also studied and practised with numerous teachers of other Yoga forms as well as various martial arts including Karate, Kung Fu and Tai Chi. His influences in Spirituality have come from Krishnamurti, teachings of Buddha, Jesus, Shiva, Yoga, as well as numerous Shamanic traditions of Native North and South Americans, from indigenous cultures of the Pacific, Tibet, Africa and Southeast Asia. Some of these traditions also include Mayan, Egyptian, and Hawaiian. His main objective is to help people develop a sacred, personal, private, safe, healing, meditative, consistent, non-dogmatic Yoga practice.  

In this episode, we're exploring the history of townhouses in New York City and unpacking how this housing type relates to gentrification, a hot-button issue at the intersection of race, class, and housing. We're revisiting a conversation that I had with Lea Cloud, co-founder and partner of CDR Studio Architects, where she walks us through a thoughtful, innovative Bushwick townhouse renovation. Townhouses are single-family, multi-level homes that share walls with other homes on one or both sides and feature an entrance directly to the street. They're most common in New York City neighborhoods like Harlem, Long Island City, and Park Slope, which also happen to be communities at the epicenter of gentrification.Gentrification is the process of changing the character of a neighborhood through the influx of more affluent residents. On the surface, the new neighbors boost the local economy with restaurants, businesses, and housing. But, these upgrades are typically at the cost of longtime residents. This shift sparks feelings of resentment, frustration, and anger about who gets to own what and who gets to call a place home.In our conversation, Lea Cloud and I touch on this issue through the lens of the townhouse renovation her firm designed for a client located in the southeast part of Bushwick. Lea describes how the neighborhood demographics have changed since it was first acquired by the Dutch in the 1600s and has now become a major hub for Central and South American immigrants. Lea and I also discuss the ethos behind passive homes, what it's like to work with multiple firms on a single project, and how to manipulate designs to meet the client's vision while still complying with standard code. Resources Mentioned: Gentrification, Displacement, and Neighborhood Revitalization by J. John Palen & Bruce LondonThe NYC TikTok Influencer to Gentrification Pipeline by Lily Alvarado About the Guest:Lea is a co-founder and partner at CDR studio architects, a full service design firm in New York. Prior to starting the firm, she was at PKSB architects, where she had an opportunity to work on the renovation of the famous Seagram building that was designed by Mies van der Rohe, Philip Johnson, Eli Cohn and Robert Jacobs. Lea serves along with me as a city planning commissioner in Hoboken, New Jersey. She's a graduate of the Rhode Island School of Design. Topics Covered:The implications of gentrification How the Bushwick neighborhood of Brooklyn has changed throughout the yearsKey features in the townhouse renovation How to incorporate light and connectivity in a designPositioning stairs in a small spaces About Your HostAtif Qadir is the Founder of Commonplace, a company dedicated to tackling one of the biggest barriers to more inclusive, affordable, and sustainable development: improving access to capital. Commonplace helps impact-driven developers and capital providers with shared values discover and connect with each other.Connect with Lea Cloud Connect with Lea on LinkedInFollow CDR Studio Architects on

Paul Hawksbee and Andy 'Davey' Jacobs are joined in the pod by author and journalist Paul Watson. Plus, South American football expert Tim Vickery is with the guys in the studio. Hosted on Acast. See acast.com/privacy for more information.

Hosts Ben & Edward are joined by Anthony Rodriguez to discuss South American kart tracks, AMA Supercross, his contract options and much more!

The latest World Agricultural Supply and Demand Report from USDA offered little change for the domestic soybean crop, but did bring significant cuts to the South American crop. See omnystudio.com/listener for privacy information.

It's Thursday, May 4th, A.D. 2023. This is The Worldview in 5 Minutes heard at www.TheWorldview.com. I'm Adam McManus. (Adam@TheWorldview.com) By Jonathan Clark Christian college student killed in Uganda over his evangelism A Christian college student was killed in Uganda last month for sharing the gospel with Muslims. Jeremiah Mwanga was attending the Uganda Christian School of Professionals in northern Uganda. His friend told Morning Star News, “Jeremiah complained about messages from one of the students threatening to kill him for misleading Muslims by preaching to them the gospel of Christ as well as converting them to the Christian faith in the school.” The attack is the latest incident of persecution reported in the East African country.  120,000 Peruvians march for life Nearly, 120,000 people participated in a pro-life march last month in Peru. Abortion is illegal in most cases in Peru. By contrast, other South American countries like Argentina and Colombia have been legalizing the murder of unborn babies in recent years. Most of Peru's population identifies as Christian with 76% in the Catholic church and 14% identifying as Protestant. Chicago City Council pays $205,000 settlement to evangelists After years of litigation, the Chicago City Council finally agreed to a $205,000 settlement with four Christian evangelists two weeks ago.  Back in 2018, security at Chicago's 24-acre Millennium Park prohibited four Wheaton College students with the Chicago Evangelism Team from sharing their faith at the park. The students filed a lawsuit in response. The case eventually led Chicago to rewrite its rules for Millennium Park, allowing more freedom for evangelists to preach and hand out literature.  Multiple students in the case told World Magazine that they plan to put the money they received from the settlement into ministry. Jeremy Chong said, “I made a personal vow that I wouldn't keep a penny of it, and that I would use it all for the sake of the Gospel. My number one desire is to plant a Reformed church in Chicago.” Vermont promotes euthanasia tourism On Tuesday, Vermont became the first state to remove the residency requirement from its euthanasia law. Now, terminally ill people from out-of-state can come to Vermont to end their lives. Currently, 10 states allow medically-assisted suicide.  Mary Hahn Beerworth with Vermont Right to Life said, “To be clear, [we] opposed the underlying concept behind assisted suicide and opposed the move to remove the residency requirement as there are still no safeguards that protect vulnerable patients from coercion.” Isaiah 59:7 says, “Their feet run to evil, and they make haste to shed innocent blood; their thoughts are thoughts of iniquity; wasting and destruction are in their paths.” Kansas: Your born sex is your sex Meanwhile, Kansas became the first state to define a person's sex as the biological sex at their birth.  Lawmakers in the state passed the law last week, overriding a veto from Democratic Governor Laura Kelly. The law would respect God's distinction between male and female in restrooms, sports programs, locker rooms, prisons, and domestic violence shelters. Presbyterian Church (USA) lost 100 congregations last year The Presbyterian Church (USA) continued its decline last year, according to its latest statistics. The mainline Protestant denomination lost over 100 congregations and over 53,000 members last year.  The PCUSA now has 1.140 million members, down from 2.5 million in 2000. A spokesperson for the denomination said their challenge is to “Look for new ways to engage and welcome young people into the fold. . . . We need to remind them that Jesus Christ is still in our midst and that means finding new, innovative ways to be church.” Apparently such innovations have included the denomination's support for abortion and sexually perverted lifestyles.  Revelation 2:5 says, “Remember therefore from where you have fallen; repent, and do the works you did at first. If not, I will come to you and remove your lampstand from its place, unless you repent.” Anniversary of the Apostle to Greenland And finally, this week is the anniversary of when Hans Egede set sail for Greenland to bring the Gospel to the Inuit people. Hans left Norway with his wife and four children in early May 1721.  He established a mission on the island and began learning the language of the local people. The work was difficult and lonely. Hans and his sons, along with other missionaries, went along the coast of Greenland spreading the Bible to the Inuit people. Their work led to several mission and trading stations, books, maps, and the first dictionary of Greenlandic language. Hans' wife died on the mission field in 1734, and he returned to Denmark the next year. His son, Paul, carried on the work. By 1744, Paul had produced a translation of the four Gospels. By 1766, the whole Testament was translated. Hans Egede is known as the Apostle of Greenland for his work. He also founded the island's capital Godthåb, now called Nuuk. To this day, Greenland is predominantly Christian with over 95% of the population identifying as Protestant.  Close And that's The Worldview in 5 Minutes on this Thursday, May 4th in the year of our Lord 2023. Subscribe by iTunes or email to our unique Christian newscast at www.TheWorldview.com. Or get the Generations app through Google Play or The App Store. I'm Adam McManus (Adam@TheWorldview.com). Seize the day for Jesus Christ.

Welcome to the All Things BMX Show. We hope you are ready for episode 154 “The Track Man” with Tom Ritz. Tom will be coming to you live from Armenia, Colombia. This show will be one for the books for sure, so you will definitely not want to miss it. So let's have some South American love and have a good party. Tom is the owner of Pump Trax USA and Tom Ritz Design. Tom's companies provide turn key solutions for full track designs, construction of tracks from international Supercross tracks to local BMX tracks along with pump tracks. Tom will be joining us on the Danger Snacks Satellite Video Line. The show starts at 8:00pm est on our Facebook, YouTube and Twitch page.Danger SnacksThe snack that is the difference between draggin' ass and haulin' ass”www.dangersnacks.comDon't forget to support the show you can send us stars on Facebook or directly send us support on our Buy Me A Coffee Page the link is in the chat. https://www.buymeacoffee.com/allthingsbmxOur Michigan studio is brought to you by Desoto BMX “Under The Big Top” https://www.facebook.com/desototxbmxThe show's chat is sponsored by BMX-Rox Photography www.roxandcoco.comOur BMX Newsmakers is brought to by 110% Nutrition www.110nutrition.com Melissa's World Famous Trivia segment brought to you by our great friends at Bombshell Racing Systems.https://b2bike.usTonight's BMX Showcase is sponsored by Answer BMXhttps://answerbmx.comResident DJ Damon is brought to you from our friends at Hotshop BMX Racing https://www.facebook.com/janehotshotbmx   The birthday shout-outs are brought to you by On Two Wheels BMX.. https://www.facebook.com/on2wheelsbmxThe show opening is brought to you by the good people at Gate Nine custom number plate.http://www.gateninedesign.com/Our open song is brought to you by the Boogie Man. Check him out on Spotify by clicking the link below.https://open.spotify.com/artist/3APaaouPhrNFJHQ25v6KC7?si=9nk-_qFZQWGOYFVl5ENffQ&dl_branch=1Our Michigan studio is brought to you by Desoto BMX “Under The Big Top” https://www.facebook.com/desototxbmxTom Ritz Contact Infohttps://www.facebook.com/tomthetrackbuilderhttps://www.facebook.com/pumptraxusahttps://www.facebook.com/profile.php?id=100063743151813https://www.tomritz.com/jason@tomritzdesigns.com(614) 302-3725LIGHTNING ROUNDhttps://www.brandedpopups.com954-594-2690sales@brandedpopups.com

Jan Rocha is a British born journalist and writer who was correspondent for the BBC World Service and The Guardian in Brazil from the 1970s to the 90s and currently writes about politics for LAB (Latin America Bureau). Her books about Brazil include Murder in the Rainforest: The Yanomami, the Gold Miners and the Amazon and Cutting the Wire (the story of the Landless Movement in Brazil) with Sue Branford, for which they won a MacArthur Foundation grant in 1999. In 2020 she published Nossa Correspondente Informa, a selection of BBC stories broadcast during the Brazilian dictatorship. Her book about the work of CLAMOR, (the Committee for the Defence of Human Rights in the countries of the Southern Cone) which she helped create in 1978, will be launched in London on April 27th under the title "CLAMOR: The search for the disappeared of the South American dictatorships". She has twice won the Vladimir Herzog Human Rights prize for journalism, in the categories of radio and books. From 2003-4 she was coordinator of an ILO project investigating the extent of slave labor in Brazil. From 2013-2014 she was a consultant to the Brazilian Truth Commission. Brazil is going through challenging times. There's never been a more important moment to understand Brazil's politics, society, and culture. To go beyond the headlines, and to ask questions that aren't easy to answer. 'Brazil Unfiltered,' does just that. This podcast is hosted by James N. Green, Professor of Brazilian History and Culture at Brown University and the National Co-Coordinator of the U.S. Network for Democracy in Brazil. Brazil Unfiltered is part of the Democracy Observatory, supported by the Washington Brazil Office. This podcast is edited and produced by Camilo Rocha in São Paulo.https://www.braziloffice.org/en/observatory#activities

When you walk into an audition room, your energy speaks before you do. Luca Pizzoleo is an independent filmmaker and photographer; he wrote, directed, and produced the award-winning short films "In The Valley Of The Moon" and "Seeking Rebirth" and his upcoming short, "The Tragic Death Of A Frenchman." Raz Fritz is a young actor who fell in love with acting as a kid. He loves embodying characters with unique and compelling stories to tell and does it in a way that transcends the screen and touches viewers. He participated in numerous award-winning independent short films and worldwide commercials.Ryan Emilio Molina is a first-generation American, the son of South American and European migrants. He left his work as a Netflix developer and distributor at Lionsgate to jump into acting. Ryan sees acting as the perfect conduit to share cultural diversity. In this episode, we delve into the details behind the creation of "In The Valley Of The Moon," a true masterpiece and the perfect example of something we often talk about in this podcast: "Don't wait for the phone to ring. Create your own projects. Raise your flag, and people will follow." Raz and Ryan talk about their approach to acting and their methods to hone their craft, and Luca talks about his approach to directing, writing, and producing. We also talk about self-tapes and in-person auditions, the importance of having fun while shooting a scene, how to create unique pieces of art with little to no budget, and more. Tune in to Episode 79 to hear from In The Valley Of The Moon cast themselves what's possible with a small budget and an immense passion.In This Episode, You Will Learn:Legos stop motion movies. A bit about Luca's first independent projects (3:30)We delve into the "In The Valley Of The Moon" cast's evolution (9:10)How did Raz prepare for his roles (18:20)You don't need a fancy camera and a gigantic crew to make a good movie (31:00)Luca shares his thoughts on self-tape auditions (43:00)The "In The Valley Of The Moon" cast reveals what advice they'd give to their younger selves (53:10)Watch In The Valley Of The Moon hereConnect with Luca:IMDBYouTubeInstagramTikTokConnect with Raz:IMDbInstagramTikTokConnect with Ryan:IMDbInstagramTikTokLet's Connect: Manhattan Actor Studio Hosted on Acast. See acast.com/privacy for more information.

On today's special episode of Markets Daily, we are introducing a new three part series. Join CoinDesk Producer Adrian Blust and Senior Reporter Eliza Grkitsi as they take a deep dive into how Bitcoin mining is making a big splash in a small, landlocked country in the middle of the South American continent.Resources:coinPY District of Columbia Energy ProfileIguazu Falls - Wikipedia Paraguay Votes Down Crypto Regulatory Bill in a Blow to Crypto Mining Industry Paraguayan Senate Passes Bill Regulating Crypto Mining and TradingParaguay's Electricity Authority Requests Higher Rates for Crypto Miners, Partial Veto of Mining LegislationElevenLabs - AI Text-to-Speech generator used for translation overdub.-This episode was written by Adrian Blust & Eliza Grkitsi, edited & produced by Adrian Blust with original music by Doc Blust.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

On today's special episode of Markets Daily, we are introducing a new three part series. Join CoinDesk Producer Adrian Blust and Senior Reporter Eliza Grkitsi as they take a deep dive into how Bitcoin mining is making a big splash in a small, landlocked country in the middle of the South American continent.Resources:coinPY District of Columbia Energy ProfileIguazu Falls - Wikipedia Paraguay Votes Down Crypto Regulatory Bill in a Blow to Crypto Mining Industry Paraguayan Senate Passes Bill Regulating Crypto Mining and TradingParaguay's Electricity Authority Requests Higher Rates for Crypto Miners, Partial Veto of Mining LegislationElevenLabs - AI Text-to-Speech generator used for translation overdub.-This episode was written by Adrian Blust & Eliza Grkitsi, edited & produced by Adrian Blust with original music by Doc Blust.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Thanks to Eva and Anbo for suggesting the harpy eagle! Further reading: Crested Eagle Feeding a Post-Fledged Young Harpy Eagle Harpy eagle with a food [By http://www.birdphotos.com - Own work, CC BY 3.0, https://commons.wikimedia.org/w/index.php?curid=3785263]: The harpy eagle has great big feet and talons: The harpy eagle with its feather crown raised [photo by Eric Kilby]: The New Guinea harpy eagle looks similar to its South American cousin [By gailhampshire from Cradley, Malvern, U.K - New Guinea Harpy Eagle. Harpyopsis novaeguineae, CC BY 2.0, https://commons.wikimedia.org/w/index.php?curid=86187611]: Ruppell's griffon vulture: Show transcript: Welcome to Strange Animals Podcast. I'm your host, Kate Shaw. We've been talking about a lot of mammals lately, so let's have an episode about birds. Anbo suggested the harpy eagle not too long ago, and a much longer time ago Eva suggested the harpy eagle and other raptors. The word raptor can be confusing because it refers to a type of small theropod dinosaur as well as a type of bird. When referring to a bird, the term raptor includes eagles, hawks, vultures, owls, and other birds of prey. And that includes the harpy eagle. The harpy eagle lives throughout much of Central and South America, although not as far south as Patagonia. It has a wingspan up to about seven feet across, or over 2 meters, and like other raptors, females are larger than males. This isn't an especially big wingspan for an eagle, but that's because the harpy eagle hunts in forests and needs short, broad wings that allow it to maneuver through branches. The harpy eagle is a beautiful bird. It has a light gray head and darker gray or black body, and is white underneath with delicate black stripes on its leg feathers, with broader stripes on its tail and wings. It has a black ring around its neck, huge yellow feet with enormous talons, and a black bill. Each talon, which is the term for a raptor's claws, can be over 5 inches long, or 13 cm, while its feet in general are bigger than a grown man's hand, even if the man has especially big hands. Most striking of all is the harpy eagle's crest, also sometimes referred to as a crown. The crown is made of long, rounded feathers and most of the time they don't show very much. When a harpy eagle is alarmed, it raises the feather crown and poofs out the feathers on its face, which makes its head look bigger and sort of owl-shaped. The harpy eagle mostly lives in lowland rainforests. It mates for life and doesn't have babies every year. Every two or three years a harpy eagle pair will build a huge nest out of sticks in the top of the tallest tree they can find. The female lays two eggs, which the parents care for together. The female spends most of her time incubating the eggs while the male brings her food, although he will also take a turn incubating while she goes out to stretch her wings and do a bit of hunting herself. When the first egg hatches, the parents bring the baby lots of food and give it lots of attention--but they ignore the other egg at that point, which usually doesn't hatch as a result. A harpy eagle chick is all white at first, and although it can fly at around 6 months old, its parents will keep feeding it for almost another year. The harpy eagle is increasingly threatened due to habitat loss and poaching. Because it's such a big bird, many people shoot it because they think it's dangerous to livestock or children. But it mostly eats monkeys, sloths, kinkajous and coatis, iguanas, and other medium-sized animals. It's rare that it attacks livestock since it mostly hunts within the tree canopy for arboreal animals. If your lambs and chickens are sitting on tree branches, you already have a bigger problem than harpy eagles eating them. A captive breeding program has been started in various zoos around the world, while conservationists work to protect the harpy eagle's natural habit...

This is Garrison Hardie with your CrossPolitic Daily News Brief for Friday, April 28th, 2023. https://www.breitbart.com/politics/2023/04/27/argentina-shuns-u-s-dollar-will-pay-for-china-imports-in-yuan/ Argentina Shuns U.S. Dollar: Will Pay for China Imports in Yuan Argentina struck a deal with Beijing on Wednesday to stop using U.S. dollars to pay for Chinese imports and embrace the yuan instead. The measure, driven by Argentina’s leftist President Alberto Fernández, is designed to relieve the South American country’s dwindling dollar reserves, AP reports. The deal further enhances China’s rise on the world stage and the diminished role of the U.S. on a host of fronts under President Joe Biden. After reaching the agreement with various companies, Argentina will use the yuan for imports from China worth about U.S.$1.04 billion from next month, accelerating trade with China as Beijing seeks to gain a further foothold in South America. In November last year Argentina expanded a currency swap with China by $5 billion in an effort to increase its yuan reserves. That agreement allowed Argentina “to work on the possibility” of advancing the rate of imports with yuan-denominated import orders being authorized in 90 days rather than the standard 180 days. The decision comes as Argentina battles critical levels in its dollar reserves amid a sharp drop in agricultural exports caused by a historic drought, as well as political uncertainty ahead of elections this year. It has also been working hard to build a relationship with Beijing after having officially joined China’s infrastructure-building Belt and Road Initiative (BRI) last year. Argentina’s government finalized a deal with Beijing soon after to construct a nuclear plant based on Chinese technology near Buenos Aires, Argentina’s national capital, in the near future. The Chinese Communist Party will reportedly provide $8 billion in financing toward the project’s $12 billion total budget. As Breitbart News reported, Argentina currently owes the International Monetary Fund (IMF) $44 billion. The international organization is in talks with Argentine authorities to finalize a fourth review of its program that includes a flexibilization of the proposed foreign exchange reserve accumulation as Argentina, whose foreign reserves are now at a $5 billion deficit, cannot comply with the current goals. https://www.foxnews.com/world/singapore-executes-man-conspired-traffic-2-pounds-cannabis Singapore executes man who allegedly conspired to traffic 2 pounds of cannabis Singapore on Wednesday executed a man accused of coordinating a cannabis delivery, despite pleas for clemency from his family and protests from activists that he was convicted on weak evidence. Tangaraju Suppiah, 46, was sentenced to death in 2018 for abetting the trafficking of 2.2 pounds of cannabis. Under Singapore laws, trafficking more than 500 grams of cannabis may result in the death penalty. Tangaraju was hanged Wednesday morning and his family was given the death certificate, according to a tweet from activist Kirsten Han of the Transformative Justice Collective, which advocates for abolishing the death penalty in Singapore. Although Tangaraju was not caught with the cannabis, prosecutors said phone numbers traced him as the person responsible for coordinating the delivery of the drugs. Tangaraju had maintained that he was not the one communicating with the others connected to the case. At a United Nations Human Rights briefing Tuesday, a spokesperson called on the Singapore government to adopt a "formal moratorium" on executions for drug-related offenses. "Imposing the death penalty for drug offences is incompatible with international norms and standards," said the spokesperson, who added that increasing evidence shows the death penalty is ineffective as a deterrent. Singapore authorities say there is a deterrent effect, citing studies that traffickers carry amounts below the threshold that would bring a death penalty. The island-state's imposition of the death penalty for drugs is in contrast with its neighbors. In Thailand, cannabis has essentially been legalized, and Malaysia has ended the mandatory death penalty for serious crimes. Singapore executed 11 people last year for drug offenses. One case that spurred international concern involved a Malaysian man whose lawyers said he was mentally disabled. https://dailycaller.com/2023/04/26/red-state-bill-religious-institutions-state-funding/ Red State Passes Bill Allowing Religious Institutions Access To State Funding The Oklahoma House of Representatives passed a bill Tuesday protecting religious institutions from being denied access to state funding. The Oklahoma Religious Freedom Act was introduced by Republican state Sen. Shane Jett and Republican state Sen. Julie Daniels to further reinforce the First Amendment by preventing the state from denying faith-based groups access to taxpayer dollars, according to the bill. The legislature passed the act Tuesday by a 64 to 27 vote, officially sending the act to Republican Gov. Kevin Stitt’s desk to be signed into law. The bill makes way for religious institutions to access state funding by barring the state from denying applications for funding “based solely on the religious character or affiliation of the person or entity.” The act adds to religious protections the state passed in 2021 preventing the government from declaring church activities non-essential, as was often the case during the COVID-19 pandemic. However, some Democrats argued that the bill was an unnecessary addition to the First Amendment, according to KFOR.com, a local media outlet. One Democratic state representative warned that the bill could lead to government funding of religious activities at religious schools. Republican state Rep. John Echols, who co-authored the bill, disagreed with his colleague’s assessment, according to KFOR.com. Oklahoma has been at the center of this discussion for some time. Earlier this month, Gov. Stitt and state Attorney General Gentner Drummond clashed over a Catholic charter school application that would have created the first state-funded religious charter school in the nation. The application was temporarily denied by the state’s virtual charter board but will be voted on again in the coming weeks. Stitt told the Daily Caller News Foundation that he was disappointed by the the attorney general’s response to the charter and continued to hope that Oklahoma would host the nation’s first state-funded religious charter school, providing more options for parents. Stitt, Jett, Daniels and Echols did not immediately respond to the Daily Caller News Foundation’s request for comment. https://thepostmillennial.com/breaking-ex-producer-suing-tucker-carlson-has-never-even-met-him?utm_campaign=64487 Ex-producer suing Tucker Carlson has never even met him Tucker Carlson Tonight producer Abby Grossberg is suing Carlson and the Fox Network over sexual behavior in the workplace, despite never having met Carlson in person. The Spectator reports that lawyers for Grossberg have confirmed that she never actually met Carlson. "Like many on the [Tucker Carlson Tonight] staff, Abby never met Tucker Carlson in person because he taped the show from his personal studios in Maine and Florida, and he did not visit Fox's NY HQ during her time there," said one of Grossberg's attorneys Kimberly A. Catala. Grossberg was the head of booking from July 2022 until she was recently placed on leave in March. She "alleges that Carlson encouraged a hostile and sexist workplace environment among his employees. Grossberg says she was subjected to bullying, antisemitic comments and sexism by staff while working out of Fox’s Manhattan office," Spectator reports. Despite never having met Carlson, Grossberg told rival network MSNBC that "Tucker and his executive producer Justin Wells, who was also fired, really were responsible for breaking me and making my life a living hell." "Since Tucker did not come to the Fox office, he relied on Justin Wells, his executive producer, and others like Alexander McCaskill, senior producer, who were present in the office every day to be his eyes, ears and mouthpiece, and to convey his ‘tone,’ as they threateningly reminded Ms. Grossberg," Catala said. The allegation per Grossberg's attorneys is that Carlson directed the "sexist" environment from afar. Apparently, the attorneys posited that Carlson had staff work as his "eyes" and "ears" in the New York office while he worked away in Maine. Carlson and Fox parted ways on Monday morning, though promos for the evening's show were already airing as the press release from Fox went out. It is unclear as to why Fox dismissed the insanely popular news anchor, though speculation abounds, including that Fox owner Rupert Murdoch took issue with Carlson's Christian beliefs. Carlson has been seen in Florida enjoying time with his wife, and laughing about finally being able to dine together on weeknights. His show has been on the air for 7 years, and in that time he amassed a loyal following. In the hours following his departure from the network, "RIP Fox News" was trending on Twitter as many viewers found they had no reason to tune in once Carlson was no longer on the air. The end of the Tucker Carlson Tonight era was celebrated by AOC, who had called for federal regulation of Fox and Carlson, which routinely took aim at her and her shenanigans. https://www.nytimes.com/2023/04/26/us/colorado-rock-throwing-arrests.html 3 Teens Charged With Murder in Rock-Throwing Spree That Killed Colorado Driver Three teenagers have been charged with first-degree murder in connection with a rock-throwing spree on Colorado roads last week that led to the death of one driver, the authorities said. The three suspects, all 18 and identified as Joseph Koenig, Nicholas Karol-Chik and Zachary Kwak, were arrested on Tuesday evening at their homes in Arvada, Colo., for taking part in a series of rock-throwing episodes on April 19 that fatally wounded Alexa Bartell, 20, who was killed when one of the rocks smashed through her windshield and struck her, the Jefferson County Sheriff’s Office announced on Wednesday. In addition to murder, the three men are charged with extreme indifference; other charges to be determined by the First Judicial District Attorney’s Office are expected. It was not immediately clear if the three, who are seniors from different high schools, had lawyers on Wednesday. The rock-throwing spree began shortly after 10 p.m. on April 19 in Westminster, Colo., which is a city of about 114,000 residents north of Denver, the authorities said. During that hour, the authorities said, the three drove a pickup truck around the county and threw large landscaping rocks at six vehicles, including a minivan and an S.U.V., hitting their windshields and driver’s side windows. Those drivers had minor or no injuries. Around 10:45 p.m., Ms. Bartell was driving north on Indiana Street when her Chevrolet Spark, a subcompact, became the last vehicle struck during the spree, the authorities said. Moments before she was killed, Ms. Bartell was on her phone talking to a friend “when the phone went silent,” according to the sheriff’s office. Her friend tracked her phone and drove to the location on Indiana Street where she found Ms. Bartell “fatally wounded inside her car, which was off the roadway in a field.” It was unclear which of the men were driving but “all three are suspected of throwing rocks,” the sheriff’s office said. They were believed to be in a black 2016 Chevrolet Silverado pickup truck. “Ultimately, mobile device forensics and supporting information from the public helped lead to the identification and arrest of the suspects,” according to the sheriff’s office, which did not release additional details. The men, who were booked into the jail at the Jefferson County Sheriff’s Office, are scheduled to appear in court on Thursday. Before we end today… how about some good news?! https://www.goodnewsnetwork.org/mom-wins-lottery-with-ticket-she-bought-celebrating-daughters-victory-over-cancer/ Mom Wins Lottery with Ticket She Bought Celebrating Daughter’s Victory Over Cancer After shelling out her life savings to pay for her daughter’s breast cancer treatment, a Florida grandmother got a nod from the universe. Buying the last available scratch-off from her preferred lottery game at the store, she landed a $2 million jackpot. Geraldine Gimblet of Lakeland was celebrating the moment that her daughter, Lawrencia Jackson, rang a bell at the local hospital signifying she had finished her breast cancer treatment. A long-time lottery player, Gimblet, 74, spent $10 on the last scratch-off card at the store, and it happened to be a winner. “I just didn’t know,” Gimblet told Good Morning America regarding her reaction,, ‘Are you sure, would you check this on your phone?’ And, I won!” Daughter Jackson, who accompanied Gimblet to the Tallahassee lottery offices to accept a lump sum of $1.6 million, described it as a “blessing.” Gimblet didn’t hesitate to finance the cancer treatment, saying she just “did what I had to do,” with Jackson adding that she would “just have to keep loving her,” as a means to try and repay the kindness. +-

This is Garrison Hardie with your CrossPolitic Daily News Brief for Friday, April 28th, 2023. https://www.breitbart.com/politics/2023/04/27/argentina-shuns-u-s-dollar-will-pay-for-china-imports-in-yuan/ Argentina Shuns U.S. Dollar: Will Pay for China Imports in Yuan Argentina struck a deal with Beijing on Wednesday to stop using U.S. dollars to pay for Chinese imports and embrace the yuan instead. The measure, driven by Argentina’s leftist President Alberto Fernández, is designed to relieve the South American country’s dwindling dollar reserves, AP reports. The deal further enhances China’s rise on the world stage and the diminished role of the U.S. on a host of fronts under President Joe Biden. After reaching the agreement with various companies, Argentina will use the yuan for imports from China worth about U.S.$1.04 billion from next month, accelerating trade with China as Beijing seeks to gain a further foothold in South America. In November last year Argentina expanded a currency swap with China by $5 billion in an effort to increase its yuan reserves. That agreement allowed Argentina “to work on the possibility” of advancing the rate of imports with yuan-denominated import orders being authorized in 90 days rather than the standard 180 days. The decision comes as Argentina battles critical levels in its dollar reserves amid a sharp drop in agricultural exports caused by a historic drought, as well as political uncertainty ahead of elections this year. It has also been working hard to build a relationship with Beijing after having officially joined China’s infrastructure-building Belt and Road Initiative (BRI) last year. Argentina’s government finalized a deal with Beijing soon after to construct a nuclear plant based on Chinese technology near Buenos Aires, Argentina’s national capital, in the near future. The Chinese Communist Party will reportedly provide $8 billion in financing toward the project’s $12 billion total budget. As Breitbart News reported, Argentina currently owes the International Monetary Fund (IMF) $44 billion. The international organization is in talks with Argentine authorities to finalize a fourth review of its program that includes a flexibilization of the proposed foreign exchange reserve accumulation as Argentina, whose foreign reserves are now at a $5 billion deficit, cannot comply with the current goals. https://www.foxnews.com/world/singapore-executes-man-conspired-traffic-2-pounds-cannabis Singapore executes man who allegedly conspired to traffic 2 pounds of cannabis Singapore on Wednesday executed a man accused of coordinating a cannabis delivery, despite pleas for clemency from his family and protests from activists that he was convicted on weak evidence. Tangaraju Suppiah, 46, was sentenced to death in 2018 for abetting the trafficking of 2.2 pounds of cannabis. Under Singapore laws, trafficking more than 500 grams of cannabis may result in the death penalty. Tangaraju was hanged Wednesday morning and his family was given the death certificate, according to a tweet from activist Kirsten Han of the Transformative Justice Collective, which advocates for abolishing the death penalty in Singapore. Although Tangaraju was not caught with the cannabis, prosecutors said phone numbers traced him as the person responsible for coordinating the delivery of the drugs. Tangaraju had maintained that he was not the one communicating with the others connected to the case. At a United Nations Human Rights briefing Tuesday, a spokesperson called on the Singapore government to adopt a "formal moratorium" on executions for drug-related offenses. "Imposing the death penalty for drug offences is incompatible with international norms and standards," said the spokesperson, who added that increasing evidence shows the death penalty is ineffective as a deterrent. Singapore authorities say there is a deterrent effect, citing studies that traffickers carry amounts below the threshold that would bring a death penalty. The island-state's imposition of the death penalty for drugs is in contrast with its neighbors. In Thailand, cannabis has essentially been legalized, and Malaysia has ended the mandatory death penalty for serious crimes. Singapore executed 11 people last year for drug offenses. One case that spurred international concern involved a Malaysian man whose lawyers said he was mentally disabled. https://dailycaller.com/2023/04/26/red-state-bill-religious-institutions-state-funding/ Red State Passes Bill Allowing Religious Institutions Access To State Funding The Oklahoma House of Representatives passed a bill Tuesday protecting religious institutions from being denied access to state funding. The Oklahoma Religious Freedom Act was introduced by Republican state Sen. Shane Jett and Republican state Sen. Julie Daniels to further reinforce the First Amendment by preventing the state from denying faith-based groups access to taxpayer dollars, according to the bill. The legislature passed the act Tuesday by a 64 to 27 vote, officially sending the act to Republican Gov. Kevin Stitt’s desk to be signed into law. The bill makes way for religious institutions to access state funding by barring the state from denying applications for funding “based solely on the religious character or affiliation of the person or entity.” The act adds to religious protections the state passed in 2021 preventing the government from declaring church activities non-essential, as was often the case during the COVID-19 pandemic. However, some Democrats argued that the bill was an unnecessary addition to the First Amendment, according to KFOR.com, a local media outlet. One Democratic state representative warned that the bill could lead to government funding of religious activities at religious schools. Republican state Rep. John Echols, who co-authored the bill, disagreed with his colleague’s assessment, according to KFOR.com. Oklahoma has been at the center of this discussion for some time. Earlier this month, Gov. Stitt and state Attorney General Gentner Drummond clashed over a Catholic charter school application that would have created the first state-funded religious charter school in the nation. The application was temporarily denied by the state’s virtual charter board but will be voted on again in the coming weeks. Stitt told the Daily Caller News Foundation that he was disappointed by the the attorney general’s response to the charter and continued to hope that Oklahoma would host the nation’s first state-funded religious charter school, providing more options for parents. Stitt, Jett, Daniels and Echols did not immediately respond to the Daily Caller News Foundation’s request for comment. https://thepostmillennial.com/breaking-ex-producer-suing-tucker-carlson-has-never-even-met-him?utm_campaign=64487 Ex-producer suing Tucker Carlson has never even met him Tucker Carlson Tonight producer Abby Grossberg is suing Carlson and the Fox Network over sexual behavior in the workplace, despite never having met Carlson in person. The Spectator reports that lawyers for Grossberg have confirmed that she never actually met Carlson. "Like many on the [Tucker Carlson Tonight] staff, Abby never met Tucker Carlson in person because he taped the show from his personal studios in Maine and Florida, and he did not visit Fox's NY HQ during her time there," said one of Grossberg's attorneys Kimberly A. Catala. Grossberg was the head of booking from July 2022 until she was recently placed on leave in March. She "alleges that Carlson encouraged a hostile and sexist workplace environment among his employees. Grossberg says she was subjected to bullying, antisemitic comments and sexism by staff while working out of Fox’s Manhattan office," Spectator reports. Despite never having met Carlson, Grossberg told rival network MSNBC that "Tucker and his executive producer Justin Wells, who was also fired, really were responsible for breaking me and making my life a living hell." "Since Tucker did not come to the Fox office, he relied on Justin Wells, his executive producer, and others like Alexander McCaskill, senior producer, who were present in the office every day to be his eyes, ears and mouthpiece, and to convey his ‘tone,’ as they threateningly reminded Ms. Grossberg," Catala said. The allegation per Grossberg's attorneys is that Carlson directed the "sexist" environment from afar. Apparently, the attorneys posited that Carlson had staff work as his "eyes" and "ears" in the New York office while he worked away in Maine. Carlson and Fox parted ways on Monday morning, though promos for the evening's show were already airing as the press release from Fox went out. It is unclear as to why Fox dismissed the insanely popular news anchor, though speculation abounds, including that Fox owner Rupert Murdoch took issue with Carlson's Christian beliefs. Carlson has been seen in Florida enjoying time with his wife, and laughing about finally being able to dine together on weeknights. His show has been on the air for 7 years, and in that time he amassed a loyal following. In the hours following his departure from the network, "RIP Fox News" was trending on Twitter as many viewers found they had no reason to tune in once Carlson was no longer on the air. The end of the Tucker Carlson Tonight era was celebrated by AOC, who had called for federal regulation of Fox and Carlson, which routinely took aim at her and her shenanigans. https://www.nytimes.com/2023/04/26/us/colorado-rock-throwing-arrests.html 3 Teens Charged With Murder in Rock-Throwing Spree That Killed Colorado Driver Three teenagers have been charged with first-degree murder in connection with a rock-throwing spree on Colorado roads last week that led to the death of one driver, the authorities said. The three suspects, all 18 and identified as Joseph Koenig, Nicholas Karol-Chik and Zachary Kwak, were arrested on Tuesday evening at their homes in Arvada, Colo., for taking part in a series of rock-throwing episodes on April 19 that fatally wounded Alexa Bartell, 20, who was killed when one of the rocks smashed through her windshield and struck her, the Jefferson County Sheriff’s Office announced on Wednesday. In addition to murder, the three men are charged with extreme indifference; other charges to be determined by the First Judicial District Attorney’s Office are expected. It was not immediately clear if the three, who are seniors from different high schools, had lawyers on Wednesday. The rock-throwing spree began shortly after 10 p.m. on April 19 in Westminster, Colo., which is a city of about 114,000 residents north of Denver, the authorities said. During that hour, the authorities said, the three drove a pickup truck around the county and threw large landscaping rocks at six vehicles, including a minivan and an S.U.V., hitting their windshields and driver’s side windows. Those drivers had minor or no injuries. Around 10:45 p.m., Ms. Bartell was driving north on Indiana Street when her Chevrolet Spark, a subcompact, became the last vehicle struck during the spree, the authorities said. Moments before she was killed, Ms. Bartell was on her phone talking to a friend “when the phone went silent,” according to the sheriff’s office. Her friend tracked her phone and drove to the location on Indiana Street where she found Ms. Bartell “fatally wounded inside her car, which was off the roadway in a field.” It was unclear which of the men were driving but “all three are suspected of throwing rocks,” the sheriff’s office said. They were believed to be in a black 2016 Chevrolet Silverado pickup truck. “Ultimately, mobile device forensics and supporting information from the public helped lead to the identification and arrest of the suspects,” according to the sheriff’s office, which did not release additional details. The men, who were booked into the jail at the Jefferson County Sheriff’s Office, are scheduled to appear in court on Thursday. Before we end today… how about some good news?! https://www.goodnewsnetwork.org/mom-wins-lottery-with-ticket-she-bought-celebrating-daughters-victory-over-cancer/ Mom Wins Lottery with Ticket She Bought Celebrating Daughter’s Victory Over Cancer After shelling out her life savings to pay for her daughter’s breast cancer treatment, a Florida grandmother got a nod from the universe. Buying the last available scratch-off from her preferred lottery game at the store, she landed a $2 million jackpot. Geraldine Gimblet of Lakeland was celebrating the moment that her daughter, Lawrencia Jackson, rang a bell at the local hospital signifying she had finished her breast cancer treatment. A long-time lottery player, Gimblet, 74, spent $10 on the last scratch-off card at the store, and it happened to be a winner. “I just didn’t know,” Gimblet told Good Morning America regarding her reaction,, ‘Are you sure, would you check this on your phone?’ And, I won!” Daughter Jackson, who accompanied Gimblet to the Tallahassee lottery offices to accept a lump sum of $1.6 million, described it as a “blessing.” Gimblet didn’t hesitate to finance the cancer treatment, saying she just “did what I had to do,” with Jackson adding that she would “just have to keep loving her,” as a means to try and repay the kindness. +-

Joining Helen Evans and Sam Homewood today for the latest episode of the UTD Podcast is midfield dynamo Fred, fresh from recently passing the landmark of 200 appearances at the heart of the Manchester United engine room. This is the most appearances from a Brazilian for the Reds and the second most from a South American, behind Antonio Valencia. Football is a high-pressure business, but the effervescent Brazilian tells us how he maintains such a positive outlook on life, always aiming to play the game with a smile on his face. Fred talks about growing up in Belo Horizonte and how blessed he feels to be playing for Manchester United, a team that he used to watch on TV as a child. He also shares with us his fascinating experience in Ukraine, playing on the road for Shakhtar Donetsk after the abandonment of their home stadium due to the conflict in the Donbass region of Ukraine. The midfielder tells us how his move to United happened, and which game is his favourite in the famous red shirt. The conversation also takes an unexpected turn when Fred expresses his love for superhero movies and UK tourism! The UTD Podcast really is the best way to get to know people who make the football club so special.The best place to catch up on the back-catalogue of our interviews is over on the Manchester United App, where you can listen to - and watch - all of our episodes in full, for free. Here you can get early access to new episodes, published 24 hours before everywhere else.If you'd like to write to the only official Manchester United Podcast then e-mail utdpodcast@manutd.co.uk For your daily fix of Manchester United news look no further than our new United Daily podcastWe'd also love it if you could leave us a rating and review wherever you listen to your podcasts. Hosted on Acast. See acast.com/privacy for more information.

The earliest studies of misoprostol's use in cervical ripening and labor induction were done by South American investigators, who reported their experience using intravaginal misoprostol. This was published in the Lancet in 1992. Despite its widespread incorporation into obstetrical practice, there's still some lack of uniformity in its administration. Is there a cumulative maximum dose allowed for cervical ripening? What about time… is there a maximal amount of time in which misoprostol can be used? Is that 12 hours, 18 hours, 24 hours? In this episode we will review important misoprostol's FDA label information, summarize position statement from the ACOG and AWHONN, and discuss issues with “scoring” the 100mcg tablet to give a 25mcg dose. And of course, we will summarize the important peer-reviewed data regarding “maximum vaginal cumulative doses” of this medication for cervical ripening/labor induction.

The city of Villa Carlos Paz is a tourist destination in central Argentina, known for a number of outdoor activities, such as kite surfing and hiking, as well as a giant cuckoo clock in the center of town. (Apparently the bird is controversial) In UFO circles, however, the town is known for one event in particular, the case of the Night Visitor. Also known as the Pretzel CEIII case, on June 14, 1968, María Elodia Pretzel was in the process of locking up the family motel, Motel La Cuesta (Known now as Hotel La Cuesta), when she would have a frightening encounter with a flattopped being carrying a strange disco ball and wearing a tight fitting suit. Strangely, María's encounter was not the only one that featured mysterious human-like figures... Zee from Ghosts-n-Heauxs joins the pod to discuss the Night Visitor case and others of the 1968 South American flap. Sources: Villa Carlos Paz - Wikipedia “Cuckoo Clock at Villa Carlos Paz” - Welcome Argentina “The Anthropomorphic Entity At Villa Carlos Paz – Part 1” by Dr. Oscar A. Galíndez, Flying Saucer Review, Vol 26, No 5, January 1981 “The Anthropomorphic Entity At Villa Carlos Paz – Part 2” by Dr. Oscar A. Galíndez, Flying Saucer Review, Vol 26, No 6, March 1981 “The Anthropomorphic Entity At Villa Carlos Paz – Part 3” by Dr. Oscar A. Galíndez, Flying Saucer Review, Vol 27, No 1, June 1981 The 1968 Humanoid Catalog “A New South American ‘Wave' by Gordon Creighton, Flying Saucer Review, Vol 14, No 5, September-October 1968 “World round-up: Argentina” by Staff Writer, Flying Saucer Review, Vol 14, No 6, November-December 1968 “One Day in Mendoza” by Charles Bowen, Flying Saucer Review, Vol 14, No 6, November-December 1968 “World round-up: Argentina” by Staff Writer, Flying Saucer Review, Vol 16, No 1, January-February 1970 “Physical Examination By ‘Miniature Martians'” by Gordon Creighton, Flying Saucer Review, Vol 15, No 5, September-October 1969 “Pretzel Case: The Opinion of a Psychologist by Alejandro Cesar Agostinelli” (Title Translated) by Alejandro Agostinelli, UFO Press, Vol 6, No 15, January 1983 “The incredible and sad story of the naive Elodia and her heartless father” (Title Translated) by Alejandro Agostinelli, UFO Press, Vol 6, No. 18, October 1983 Theme song: "Ufo" by Floats, available on Soundcloud, iTunes and Spotify Logo designed by Megan Lagerberg T-Shirt Designs by The Great Desdymona Welcome UFO People Prints Are Now Available!  Check out ourstrangeskies.com for all things related to the podcast! Learn more about your ad choices. Visit megaphone.fm/adchoices

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