Iranian biologist
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How do you navigate a career path when the future of work is uncertain? How important is mentorship versus immediate impact? Is it better to focus on your strengths or on the world's most pressing problems? Should you specialise deeply or develop a unique combination of skills?From embracing failure to finding unlikely allies, we bring you 16 diverse perspectives from past guests who've found unconventional paths to impact and helped others do the same.Links to learn more and full transcript.Chapters:Cold open (00:00:00)Luisa's intro (00:01:04)Holden Karnofsky on just kicking ass at whatever (00:02:53)Jeff Sebo on what improv comedy can teach us about doing good in the world (00:12:23)Dean Spears on being open to randomness and serendipity (00:19:26)Michael Webb on how to think about career planning given the rapid developments in AI (00:21:17)Michelle Hutchinson on finding what motivates you and reaching out to people for help (00:41:10)Benjamin Todd on figuring out if a career path is a good fit for you (00:46:03)Chris Olah on the value of unusual combinations of skills (00:50:23)Holden Karnofsky on deciding which weird ideas are worth betting on (00:58:03)Karen Levy on travelling to learn about yourself (01:03:10)Leah Garcés on finding common ground with unlikely allies (01:06:53)Spencer Greenberg on recognising toxic people who could derail your career and life (01:13:34)Holden Karnofsky on the many jobs that can help with AI (01:23:13)Danny Hernandez on using world events to trigger you to work on something else (01:30:46)Sarah Eustis-Guthrie on exploring and pivoting in careers (01:33:07)Benjamin Todd on making tough career decisions (01:38:36)Hannah Ritchie on being selective when following others' advice (01:44:22)Alex Lawsen on getting good mentorship (01:47:25)Chris Olah on cold emailing that actually works (01:54:49)Pardis Sabeti on prioritising physical health to do your best work (01:58:34)Chris Olah on developing good taste and technique as a researcher (02:04:39)Benjamin Todd on why it's so important to apply to loads of jobs (02:09:52)Varsha Venugopal on embracing uncomfortable situations and celebrating failures (02:14:25)Luisa's outro (02:17:43)Audio engineering: Ben Cordell, Milo McGuire, Simon Monsour, and Dominic ArmstrongContent editing: Katy Moore and Milo McGuireTranscriptions and web: Katy Moore
What did the 2014 Ebola outbreak teach us about preventing future pandemics? Our guests this week, Christian Happi and Pardis Sabeti, are world experts on disease surveillance, and have worked together fighting infectious disease in Africa for over a decade. Happi shares a gripping account of how he courageously helped stop Ebola from spreading in Nigeria during the 2014 West Africa outbreak. Then Sabeti explains how a new era of surveillance may help prevent future pandemics.See omnystudio.com/listener for privacy information.
What did the 2014 Ebola outbreak teach us about preventing future pandemics? Our guests this week, Christian Happi and Pardis Sabeti, are world experts on disease surveillance, and have worked together fighting infectious disease in Africa for over a decade. Happi shares a gripping account of how he courageously helped stop Ebola from spreading in Nigeria during the 2014 West Africa outbreak. Then Sabeti explains how a new era of surveillance may help prevent future pandemics.See omnystudio.com/listener for privacy information.
Laura Luebbert just finished her PhD in computational biology and will soon be a postdoc with Pardis Sabeti, to hunt some viruses. We talk about how she got into biology, how she created a widely-used software project (gget) with no prior coding experience, her recent reports when she discovered questionable data in key papers about honeybee dances, and much more.BJKS Podcast is a podcast about neuroscience, psychology, and anything vaguely related, hosted by Benjamin James Kuper-Smith.Support the show: https://geni.us/bjks-patreonTimestamps0:00:00: Why Laura studied biology in Leiden/the Netherlands (and the importance of early scientific training)0:13:41: How Laura ended up doing a PhD at Caltech with Lior Pachter (and how to choose one project if you're interested in many things)0:22:00: gget: Developing and maintaining a software tool with no prior programming experience0:54:07: Laura's future postdoc (with Pardis Sabeti): global virus-hunter0:59:34: Finding and reporting questionable data in published papers about honeybee dances1:36:43: A book or paper more people should read1:38:55: Something Laura wishes she'd learnt sooner1:40:38: Advice for PhD students/postdocs1:44:02: Bonus: should I learn Catalan?Podcast linksWebsite: https://geni.us/bjks-podTwitter: https://geni.us/bjks-pod-twtLaura's linksWebsite: https://geni.us/luebbert-webGoogle Scholar: https://geni.us/luebbert-scholarTwitter: https://geni.us/luebbert-twtBen's linksWebsite: https://geni.us/bjks-webGoogle Scholar: https://geni.us/bjks-scholarTwitter: https://geni.us/bjks-twtReferences and linksEpisode with Jessica Polka: https://geni.us/bjks-polkaEpisode with Elisabeth Bik: https://geni.us/bjks-bikEpisode with Joe Hilgard: https://geni.us/bjks-hilgardPrototype fund Germany: https://prototypefund.de/en/PubPeer: https://pubpeer.com/Aaronovitch (2014-). Rivers of London series.Frisch (1927). Aus dem Leben der Bienen.Luebbert, Sullivan, Carilli, Hjörleifsson, Winnett, Chari & Pachter (2023). Efficient and accurate detection of viral sequences at single-cell resolution reveals putative novel viruses perturbing host gene expression. bioRxiv.Luebbert & Pachter (2023). Efficient querying of genomic reference databases with gget. Bioinformatics.Luebbert & Pachter (2024). The miscalibration of the honeybee odometer. arXiv.https://liorpachter.wordpress.com/2024/07/02/the-journal-of-scientific-integrity/
Dr. Mireille Kamariza is an Assistant Professor in the Department of Bioengineering at UCLA and co-founder and CEO of OliLux Biosciences, a company dedicated to providing low- cost, portable and reliable diagnostic devices in low-resource settings. She is a chemical biologist with expertise building diagnostics tools against infectious organisms. With a background in chemical biology and infectious disease research, she researches new tools to selectively probe molecular activity of live cells, in real-time, with versatile applications in research and medicine. She was previously a Junior Fellow at the Harvard Society of Fellows working with Prof. Pardis Sabeti at the Broad Institute of Harvard and MIT. There, she worked on developing CRISPR-Cas13 assays to detect bloodborne viruses such as Ebolavirus, Lassa virus, Yellow Fever virus, and many others. Prior to her appointment at Harvard, she completed her doctoral studies in Biology at Stanford University where she developed a new diagnostic technology for the rapid and simple detection of tuberculosis at the point-of-care. This project was awarded a Bill & Melinda Gates Foundation grant to test their diagnostic devices in places with high levels of disease. In addition, her work was translated into what is now OliLux Biosciences. Dr. Kamariza has received numerous awards, including being named as one of Chemical & Engineering News's Talented 12 in 2020 and Endpt's 20 under 40 in 2023. In December 2022, Nature Medicine named Dr. Kamariza as one of 11 early-career researchers to watch. --- Support this podcast: https://podcasters.spotify.com/pod/show/theia-hc/support
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Dan talks with Lara Salahi, a professor of journalism at Endicott College, where she teaches a range of courses, from feature writing to digital journalism. She has also been a digital producer for NBC Universal, and a field producer for ABC News. Salahi has also done some consulting and writing on science and health projects. She was executive producer on a podcast called Track the Vax, which ran during the height of the pandemic. And she collaborated with Pardis Sabeti, a systems biologist and Harvard professor who researches infectious diseases like Ebola and Lassa virus. They wrote a book together in 2018 that is still relevant: It's called "Outbreak Culture: The Ebola Crisis and the Next Epidemic." They updated the paperback with a new preface and epilogue in 2021 to reflect on the Covid19 outbreak, and the lessons learned from past epidemics. In Quick Takes, there's so much going on that Dan discusses three developments. One involves the future ownership of the Portland Press Herald in Maine as well as its sister papers. The other is about a dramatic, unexpected development in hyperlocal news in New Jersey. The third involves some very good news for a daily paper in central Pennsylvania. Dan and his Northeastern University colleague, Meg Heckman, pay tribute to a legendary journalist — Mike Pride, the retired editor of the Concord Monitor in New Hampshire and the former administrator of the Pulitzer Prize. Mike died on April 24 in Florida of a blood disorder. He was 76, and left his imprint on journalism in many ways. Meg worked at the Concord Monitor for more than 10 years. Ellen was out of pocket for this podcast episode but did the sound editing and post-production. She'll return next week.
For this edition, we hear from Aoife Brennan, president and CEO of Synlogic Inc., and Dr. Pardis Sabeti, who heads her own lab mapping the genome to discover new cures for diseases.
This month, we look at the exciting world of biotech, and hear from Dr. Pardis Sabeti, who heads her own lab mapping the genome to discover new cures for diseases, and Dr. Aoife Brennan, president and CEO of Synlogic, Inc., a clinical stage company creating transformative medicines.
As we saw with the Ebola outbreak--and the disastrous early handling of the COVID-19 coronavirus pandemic--a lack of preparedness, delays, and system-wide problems with the distribution of critical medical supplies can have deadly consequences. Yet after every outbreak, the systems put in place to coordinate emergency responses are generally dismantled. One of America's top biomedical researchers, Dr. Pardis Sabeti, and her Pulitzer Prize-winning collaborator, Lara Salahi, argue that these problems are built into the ecosystem of our emergency responses. With an understanding of the path of disease and insight into political psychology, they show how secrecy, competition, and poor coordination plague nearly every major public health crisis and reveal how much more could be done to safeguard the well-being of caregivers, patients, and vulnerable communities. A work of fearless integrity and unassailable authority, Outbreak Culture: The Ebola Crisis and the Next Epidemic (Harvard UP, 2021) seeks to ensure that we make some urgently needed changes before the next pandemic. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network
As we saw with the Ebola outbreak--and the disastrous early handling of the COVID-19 coronavirus pandemic--a lack of preparedness, delays, and system-wide problems with the distribution of critical medical supplies can have deadly consequences. Yet after every outbreak, the systems put in place to coordinate emergency responses are generally dismantled. One of America's top biomedical researchers, Dr. Pardis Sabeti, and her Pulitzer Prize-winning collaborator, Lara Salahi, argue that these problems are built into the ecosystem of our emergency responses. With an understanding of the path of disease and insight into political psychology, they show how secrecy, competition, and poor coordination plague nearly every major public health crisis and reveal how much more could be done to safeguard the well-being of caregivers, patients, and vulnerable communities. A work of fearless integrity and unassailable authority, Outbreak Culture: The Ebola Crisis and the Next Epidemic (Harvard UP, 2021) seeks to ensure that we make some urgently needed changes before the next pandemic. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/medicine
As we saw with the Ebola outbreak--and the disastrous early handling of the COVID-19 coronavirus pandemic--a lack of preparedness, delays, and system-wide problems with the distribution of critical medical supplies can have deadly consequences. Yet after every outbreak, the systems put in place to coordinate emergency responses are generally dismantled. One of America's top biomedical researchers, Dr. Pardis Sabeti, and her Pulitzer Prize-winning collaborator, Lara Salahi, argue that these problems are built into the ecosystem of our emergency responses. With an understanding of the path of disease and insight into political psychology, they show how secrecy, competition, and poor coordination plague nearly every major public health crisis and reveal how much more could be done to safeguard the well-being of caregivers, patients, and vulnerable communities. A work of fearless integrity and unassailable authority, Outbreak Culture: The Ebola Crisis and the Next Epidemic (Harvard UP, 2021) seeks to ensure that we make some urgently needed changes before the next pandemic. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/african-studies
As we saw with the Ebola outbreak--and the disastrous early handling of the COVID-19 coronavirus pandemic--a lack of preparedness, delays, and system-wide problems with the distribution of critical medical supplies can have deadly consequences. Yet after every outbreak, the systems put in place to coordinate emergency responses are generally dismantled. One of America's top biomedical researchers, Dr. Pardis Sabeti, and her Pulitzer Prize-winning collaborator, Lara Salahi, argue that these problems are built into the ecosystem of our emergency responses. With an understanding of the path of disease and insight into political psychology, they show how secrecy, competition, and poor coordination plague nearly every major public health crisis and reveal how much more could be done to safeguard the well-being of caregivers, patients, and vulnerable communities. A work of fearless integrity and unassailable authority, Outbreak Culture: The Ebola Crisis and the Next Epidemic (Harvard UP, 2021) seeks to ensure that we make some urgently needed changes before the next pandemic. Learn more about your ad choices. Visit megaphone.fm/adchoices
In this eighth interview of the “17 Rooms'' podcast, Steve Davis and Pardis Sabeti discuss the uptake of participatory digital health tools for pandemic preparedness and response. Davis, senior strategy advisor and Interim China Country director at the Bill & Melinda Gates Foundation and Sabeti, professor at Harvard University, moderated Room 3 focused on Sustainable Development Goal number 3—on good health and well-being—during the 2021 17 Rooms flagship process. “17 Rooms” is a podcast about actions, insights, and community for the Sustainable Development Goals and the people driving them. The podcast is co-hosted by John McArthur—senior fellow and director of the Center for Sustainable Development at The Brookings Institution, and Zia Khan—senior vice president for innovation at The Rockefeller Foundation. Show notes and transcript: https://brook.gs/3HdPQER "17 Rooms" is part of the Brookings Podcast Network. Subscribe and listen on Apple, Spotify, Google Podcasts, or wherever you listen to podcasts. Send feedback to podcasts@brookings.edu, and follow and tweet at @policypodcasts on Twitter.
She was one of the first Biologists IN THE WORLD to get the call when Covid-19 was discovered. In this podcast we discuss with Leading Computational Genetesist Dr Pardis Sabeti, how the Science world reacted to the virus, how politicians have fared, and what we all need to know if we're to deal with outbreaks in the future.zABOUT DR PARDIS SABETIDr. Pardis Sabeti is a rock star Harvard Biologist, a TIME Person of the Year, and has been dubbed the 'Ebola Detective' following her work at the centre of the outbreak in Sierra Leone. She's a computational genetesist and describes her work as 'in the most basic terms, natural selection' mapping the genome sequences of virus to determine how they behave, and how to fight them. Dr Sabeti is on the board of the BROAD Institute of Harvard and MIT.***For suggestions and questions, WhatsApp the producers on +44 773 539 4284Follow us on Social @jaxandmartinpodJoin our online community: www.jaxandmartinshow.comWATCH the full interviews on YouTube: www.youtube.com/channel/UCdSIrHS7Lz3whqqKyTVziUA/videos Hosted on Acast. See acast.com/privacy for more information.
When the first person with COVID-19 went to see a doctor in Wuhan, nobody could tell that it wasn't a familiar disease like the flu - that we were dealing with something new. How much death and destruction could we have avoided if we'd had a hero who could? That's what the last Assistant Secretary of Defense Andy Weber asked on the show back in March. Today's guest Pardis Sabeti is a professor at Harvard, fought Ebola on the ground in Africa during the 2014 outbreak, runs her own lab, co-founded a company that produces next-level testing, and is even the lead singer of a rock band. If anyone is going to be that hero in the next pandemic - it just might be her. Links to learn more, summary and full transcript. She is a co-author of the SENTINEL proposal, a practical system for detecting new diseases quickly, using an escalating series of three novel diagnostic techniques. The first method, called SHERLOCK, uses CRISPR gene editing to detect familiar viruses in a simple, inexpensive filter paper test, using non-invasive samples. If SHERLOCK draws a blank, we escalate to the second step, CARMEN, an advanced version of SHERLOCK that uses microfluidics and CRISPR to simultaneously detect hundreds of viruses and viral strains. More expensive, but far more comprehensive. If neither SHERLOCK nor CARMEN detects a known pathogen, it's time to pull out the big gun: metagenomic sequencing. More expensive still, but sequencing all the DNA in a patient sample lets you identify and track every virus - known and unknown - in a sample. If Pardis and her team succeeds, our future pandemic potential patient zero may: 1. Go to the hospital with flu-like symptoms, and immediately be tested using SHERLOCK - which will come back negative 2. Take the CARMEN test for a much broader range of illnesses - which will also come back negative 3. Their sample will be sent for metagenomic sequencing, which will reveal that they're carrying a new virus we'll have to contend with 4. At all levels, information will be recorded in a cloud-based data system that shares data in real time; the hospital will be alerted and told to quarantine the patient 5. The world will be able to react weeks - or even months - faster, potentially saving millions of lives It's a wonderful vision, and one humanity is ready to test out. But there are all sorts of practical questions, such as: * How do you scale these technologies, including to remote and rural areas? * Will doctors everywhere be able to operate them? * Who will pay for it? * How do you maintain the public's trust and protect against misuse of sequencing data? * How do you avoid drowning in the data the system produces? In this conversation Pardis and Rob address all those questions, as well as: * Pardis' history with trying to control emerging contagious diseases * The potential of mRNA vaccines * Other emerging technologies * How to best educate people about pandemics * The pros and cons of gain-of-function research * Turning mistakes into exercises you can learn from * Overcoming enormous life challenges * Why it's so important to work with people you can laugh with * And much more Producer: Keiran Harris. Audio mastering: Ben Cordell. Transcriptions: Sofia Davis-Fogel.
Dr. Pardis Sabeti is an institute member of the Broad Institute of Harvard and MIT and a professor at Harvard University and the Harvard T.H. Chan School of Public Health. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. Y. Botti-Lodovico, E. Rosenberg, and P.C. Sabeti. Testing in a Pandemic — Improving Access, Coordination, and Prioritization. N Engl J Med 2021;384:197-199.
When the deadly Ebola virus broke out in West Africa in 2014, scientists in the USA set to work analysing it. What they discovered would eventually lead to a treatment. Pardis Sabeti is a virologist at Harvard University and leads the team who sequenced the Ebola virus genome - she has been speaking to Ibby Caputo for Witness History. Photo: Pardis Sabeti (front row, right) with some of the team who sequenced the virus in the lab.
Join Inés as she talks to Dr. Pardis Sabeti and Dr. Greg Davis about how gene-editing technologies like CRISPR are shaping the future of precision medicine.
We invite Pardis back to hear her account from the front lines in the fight against the coronavirus. She’s a leader in scientific breakthroughs aimed at stopping its insidious ability to spread undetected. Support the show: https://www.aldacommunicationtraining.com/podcasts/
As the world continues to fight against COVID-19, the United States is reopening to try to save its economy. Since our last episode on COVID-19 360 Perspective in April, the central questions for handling the situation have evolved, technologies are emerging, and consensus remains on the significance of testing. So, what is the current state of diagnostics now, as the country heads into the fall? In this episode, we explore COVID-19 diagnostics from experts in Biotech companies, research labs, biological resource sharing centers, and other newly established centers to facilitate the development of innovations and testing that flatten the COVID-19 curve.“How we’ll fight the next deadly virus” by Pardis Sabeti, TEDWomen 2015 is licensed under CC BY-NC-ND 4.0.“Inspired” by Kevin MacLeod is licensed under CC BY 4.0.
Kimberly Robinson of Bloomberg Law on the SCOTUS rulings. Pardis Sabeti of Harvard Univ on a virus detection network. Danielle Allen of Harvard Univ on American democracy in the 21st century. Thomas Gill of the Univ of Texas at El Paso on the Saharan dust cloud. Radley Horton of Columbia Univ on superheat events. Scott Freeman of the Univ of Washington on chemistry bottleneck.
¿Cómo podemos detener la próxima pandemia antes de que empiece? Los investigadores de enfermedades, Pardis Sabeti y Christian Happi, introducen Sentinel, un sistema de alerta temprana que detecta y rastrea amenazas virales a tiempo real -- y que pudiera ayudar a detenerlas antes de que esparzan. Aprende más sobre la tecnología de punta que basa al sistema y como el equipo Sentinel esta ayudando a los científicos y trabajadores de salud durante la pandemia del coronavirus. (Este ambicioso plan es parte del Proyecto Audaz (Audacious Project), una iniciativa de TED para inspirar y financiar cambios globales).
우리는 어떻게 해야 향후 다가올 대유행병이 발병하기 전에 이를 막을 수 있을까요? 질병 연구자인 파디스 사베티와 크리스찬 합피는 실시간으로 바이러스 위협을 감지하고 추적하는 조기 경보 시스템 '센티넬'을 도입했고, 이 시스템을 통해 대유행병의 확산을 막을 수 있을 것이라 말합니다. 시스템에 동력을 공급하는 최첨단 기술과 센티넬 팀이 어떻게 COVID-19 유행 기간 동안 과학자들과 보건 종사자들을 돕고 있는지 자세히 알아봅니다. (이 야심 찬 계획은 전 세계적인 변화를 고무하고 후원하기 위한 TED의 창의적이고 대담한 프로젝트의 일부입니다.)
Wie können wir die nächste Pandemie stoppen bevor sie überhaupt beginnt? Krankheitsforscher Pardis Sabeti und Christian Happi stellen Sentinel vor: Ein Frühwarnsystem, das Virusinfektionen in Echtzeit aufspürt und nachverfolgt -- und sie so stoppen könnte bevor sie sich ausbreiten. Lernen Sie mehr über die neuartige Technologie, die dieses System antreibt und wie das Sentinel Team Forschern und Gesundheitspersonal während der Corona-Pandemie hilft. (Dieser ehrgeizige Plan ist Teil des Audacious Project, TEDs Initiative, um globale Veränderungen zu inspirieren und zu fördern).
How can we stop the next pandemic before it starts? Disease researchers Pardis Sabeti and Christian Happi introduce Sentinel, an early warning system that detects and tracks viral threats in real time -- and could help stop them before they spread. Learn more about the cutting-edge technology that powers the system and how the Sentinel team is helping scientists and health workers during the coronavirus pandemic. (This ambitious plan is part of the Audacious Project, TED's initiative to inspire and fund global change.)
Como podemos deter a próxima pandemia antes de seu início? Os pesquisadores de doenças Pardis Sabeti e Christian Happi apresentam Sentinel, um sistema de alerta antecipado que detecta e rastreia ameaças virais em tempo real e pode ajudar a detê-las antes que elas se espalhem. Saiba mais sobre a tecnologia de ponta que alimenta o sistema e como a equipe do Sentinel está ajudando cientistas e profissionais de saúde durante a pandemia do novo coronavírus. (Este plano ambicioso faz parte do Audacious Project, uma iniciativa do TED para inspirar e financiar mudanças globais.)
Comment arrêter la prochaine pandémie avant qu'elle commence ? Les chercheurs Pardis Sabeti et Christian Happi présentent Sentinel, un système d'alarme précoce qui détecte et suit les menaces virales en temps réel -- et qui pourrait aider à les arrêter avant de leur propagation. Apprenez-en davantage sur la technologie de pointe qui alimente ce système et sur la façon dont l'équipe Sentinel aide les scientifiques et le personnel de soin de santé pendant la pandémie de coronavirus. (Ce plan ambitieux fait partie du projet Audacious, l'initiative de TED pour inspirer et financer le changement mondial.)
How can we stop the next pandemic before it starts? Disease researchers Pardis Sabeti and Christian Happi introduce Sentinel, an early warning system that detects and tracks viral threats in real time -- and could help stop them before they spread. Learn more about the cutting-edge technology that powers the system and how the Sentinel team is helping scientists and health workers during the coronavirus pandemic. (This ambitious plan is part of the Audacious Project, TED's initiative to inspire and fund global change.)
How can we stop the next pandemic before it starts? Disease researchers Pardis Sabeti and Christian Happi introduce Sentinel, an early warning system that detects and tracks viral threats in real time -- and could help stop them before they spread. Learn more about the cutting-edge technology that powers the system and how the Sentinel team is helping scientists and health workers during the coronavirus pandemic. (This ambitious plan is part of the Audacious Project, TED's initiative to inspire and fund global change.)
How can we stop the next pandemic before it starts? Disease researchers Pardis Sabeti and Christian Happi introduce Sentinel, an early warning system that detects and tracks viral threats in real time -- and could help stop them before they spread. Learn more about the cutting-edge technology that powers the system and how the Sentinel team is helping scientists and health workers during the coronavirus pandemic. (This ambitious plan is part of the Audacious Project, TED's initiative to inspire and fund global change.)
Pardis Sabeti, a computational biologist at Harvard and the Broad Institute, discusses when and how to re-open colleges and universities, why the US is behind other countries when it comes to containing the spread of coronavirus, and a plan to stop pandemics in the future Learn more about your ad choices. Visit podcastchoices.com/adchoices
The hosts interview a panel of distinguished guests, including life sciences entrepreneur and investor Alexis Borisy, Finale Doshi-Velez of Harvard University's John A. Paulson School of Engineering and Applied Sciences, and Pardis Sabeti of the Broad Institute of MIT and Harvard.
Season 1 Episode 13 - The Meaningful Life of Pardis Sabeti Check out my series PEP TALK at https://www.youtube.com/watch?v=b44RbJ91s6E&list=PLm3cd8rbs9s6Xu1tv5oqWRHnURppiWd1l YouTube channel: https://www.youtube.com/c/AliLudlow To support me and help keep this podcast Ad-free, you can leave me donations at https://www.paypal.com/cgi-bin/webscr?cmd=_s-xclick&hosted_button_id=7973NC44FDFRL&source=url - anything at all is TREMENDOUSLY APPRECIATED :) Connect with me! - Instagram: https://www.instagram.com/aliludlow/ - Facebook: https://www.facebook.com/TheAliLudlow/ --- Send in a voice message: https://anchor.fm/aliludlow/message
The Ebola outbreak in The Democratic Republic of Congo is slowing down, and a new Ebola vaccine is likely to get approved by the European Commission. Leading Ebola researcher Pardis Sabeti reflects on what she has learned from fighting a disease that may soon be vanquished. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Despite many positive changes, women in science report continuing problems. When a colleague ignores your contribution, belittles your work, or even harasses you, what do you do? Women have been leading a revolution in science for many years, and their voices are now being heard like never before. In this special episode of Clear+Vivid, Alan Alda and his producers speak with pioneers in the revolution, their mentees, and some of today’s most outspoken advocates for professional women in the STEM fields. They have a lot to teach us about how to bring about equity for women in science— and how to keep it. Joining us in the studio and on location in their labs, we hear from Melinda Gates, Jo Handelsman, Nancy Hopkins, Hope Jahren, Pardis Sabeti, Leslie Vosshall, and many more. This special episode dives deep into the most troubling issues facing career women in science and offers real insight about what works, what doesn’t, and what we can all do to secure a more equal and fair future. Support the show.
Pardis Sabeti is a co-founder of Sherlock Biosciences, the head of the Sabeti Lab, and a co-author of Outbreak Culture. Her conversation with Nature Biotechnology covers her family fleeing the Iranian revolution, the Sabeti Lab's role in the Ebola outbreak of 2014-2016, and the ATV accident that nearly killed her. See acast.com/privacy for privacy and opt-out information.
Join Inés as she talks to Dr. Pardis Sabeti and Dr. Greg Davis about how gene-editing technologies like CRISPR are shaping the future of precision medicine.
Join Inés as she talks to Dr. Pardis Sabeti and Dr. Greg Davis about how gene-editing technologies like CRISPR are shaping the future of precision medicine.
At Harvard, she's known as the "rollerblading, rockstar scientist." Pardis Sabeti mines the human genome for its secrets to eradicate deadly scourges. Her breakthrough work helped tackle an outbreak of the deadly Ebola virus in Africa. She also finds time to write and perform with a rock band. In this episode, Pardis and Alan Alda talk about her extraordinary work, and how to tackle any challenge with empathy, humanity, and a whole lot of fun. Support the show.
In their new book, Outbreak Culture: The Ebola Crisis and the Next Epidemic, Dr. Pardis Sabeti and journalist Lara Salahi argue that epidemics don’t just spread deadly diseases, they can also breed a toxic culture among those who are helping.
We were honored to sit with the amazing Pardis Sabeti who is doing her part to help those in need with her work at The Sabeti Lab where she is working to eradicate the Lassa and Ebola viruses. Dr. Sabeti completed her undergraduate degree at MIT, her graduate work at Oxford University as a Rhodes Scholar, got her medical degree from Harvard Medical School and she was named a TIME magazine ‘Person of the Year’ as one of the Ebola fighters. But perhaps the coolest thing she does is perform as the lead singer and co-songwriter of the Boston based rock band Thousand Days. Song List: Song 1: Breathe In (Turkana Boy) Song 2: One Truth (Small Joys) Song 3: Phoenix (Single) Song 4: Neda (Radiate)
Andrés Colubri (@codeanticode) on how he manages to do seemingly different things—such as art, computational biology, or open-source development—by connecting them around one overarching theme. Andrés grew up in Buenos Aires, Argentina, where he obtained his doctoral degree in mathematics at the Universidad Nacional el Sur. After living in the United States for a while, he went back to Buenos Aires to distance himself from the academic scene and revisit his interests on the visual arts, drawing, and animation. It was then when he crossed paths—and got hooked—with the world of creative coding, where art and computation join as one. On his way back to the United States, Andrés got heavily involved with creating art with code, and became a major contributor to the Processing open-source project—what would become an international entry point to computer programming for artists and designers. He leads the Processing for Android initiative, and recently released Processing for Android: Create Mobile, Sensor-Aware, and VR Applications Using Processing. During weekdays, Andrés walks (or bikes) to work at the Sabeti Lab in Cambridge, Massachusetts, as a computational scientist—where he helps develop methods to detect and investigate natural selection in the genome of humans and other species, and to examine the genetic factors and signals of natural selection in pathogens such as the Ebola virus. Links Processing is an open-source computer programming language and development environment commonly used for creative endeavors such as live installations and digital art. Andrés has been involved in the development of its core functionality for several years now. Processing was initiated by John Maeda's students Casey Reas and Ben Fry, who built on Maeda's previous work (Design By Numbers). Design by Numbers was an experiment to teach programming led by John Maeda at the MIT Media Lab in the 1990s, with the intention of offering an easy entry point to computer programming to non-programmers (such as designers and artists). The protein folding problem is "the obstacle that scientists confront when they try to predict 3D structure of proteins based on their amino acid sequence." Shaders are "a type of computer program that was originally used for shading (the production of appropriate levels of light, darkness, and color within an image) but which now performs a variety of specialized functions in various fields of computer graphics special effects or does video post-processing unrelated to shading, or even functions unrelated to graphics at all." The Emotional Life of Books is an experiment that uses the emotional judgement of readers to inform how books are organized in the Garden Library for Refugees and Migrant Workers. Processing for Android was initiated by Ben Fry and Jonathan Feinberg. Processing for Android: Create Mobile, Sensor-Aware, and VR Applications Using Processing with Processing by Andrés Colubri. The Sabeti Lab, headed by Pardis Sabeti, is part of the FAS Center for Systems Biology at Harvard University, and maintains close ties to the Broad Institute of Harvard and MIT. It uses computational methods and genomics to understand mechanisms of evolutionary adaptation in humans and pathogens. Mirador is "a tool for visual exploration of complex datasets [that was the result of a collaboration between between Fathom Information Design and the Sabeti Lab.] It enables users to discover correlation patterns and derive new hypotheses from the data." Alone Together: Why We Expect More from Technology and Less from Each Other by Sherry Turkle. Patrick H. Winston is Ford Professor of Artificial Intelligence and Computer Science at the Massachusetts Institute of Technology. Submit your questions and I'll try to answer them in future episodes. I'd love to hear from you. If you enjoy the show, would you please consider leaving a short review on Apple Podcasts/iTunes? It takes less than 60 seconds and really helps. Show notes, transcripts, and past episodes at gettingsimple.com/podcast. Theme song Sleep by Steve Combs under CC BY 4.0. Follow Nono Twitter.com/nonoesp Instagram.com/nonoesp Facebook.com/nonomartinezalonso YouTube.com/nonomartinezalonso
A scientist sequences outbreak viral genomes--and shares the data--to help the world stay on top of the next Ebola or Zika.
"Some people go to sleep and have God appear in their dreams. I just looked her up" - Sudev Namboodiri Remarkable. If you didn't pass 5th grade, you have no idea what that word means. But, when something's remarkable - you know it when you see it. On this episode, we talk to the founders of a fake religion and then, one of TIME's People of the Year to uncover how to transform your working life by being remarkable. Plus: - How do you become the most interesting woman in the world? - What happens when you meet strangers on the internet? - What are the inner-mechanics of being remarkable and how can you use them to your advantage? - How do you build the foundation for a deep, focused career? - What happened to Pardis Sabeti in 2015 that really, really sucked? For more material on this episode, go to realtalkstudio.com. P.S. Sign up for the email list here. Production and Special Credits Special Guests: Pardis Sabeti, Sudev, Amanda, and Paca Host, Producer, Sound Design, Research: Mohnish Soundararajan Co-Host: Kevin Sanji Feedback: Kevin Sanji and Justine Brumm Special Music: "Turkana Boy" by Thousand Days Intro Music: Electric Mantis
Dr. Pardis Sabeti is an Associate Professor at the Center for Systems Biology and Department of Organismic and Evolutionary Biology at Harvard University and the Department of Immunology and Infectious Disease at the Harvard School of Public Health, and an Institute Member of the Broad Institute of Harvard and MIT, and a Howard Hughes Investigator. Dr. Sabeti is a computational geneticist with expertise developing algorithms to detect genetic signatures of adaption in humans and the microbial organisms that infect humans. Her lab’s key research areas include: (1) Developing analytical methods to detect and investigate evolution in the genomes of humans and other species (2) Examining host and viral genetic factors driving disease susceptibility to the devastating and deadly diseases in West Africa, Ebola Virus Disease and Lassa hemorrhagic fever. (3) Investigating the genomes of microbes, including Lassa virus, Ebola virus, Plasmodium falciparum malaria, Vibrio cholera, and Mycobacterioum tuberculosis to help in the development of intervention strategies. (4) Determining the microbial cause of undiagnosed acute febrile illness. Dr. Sabeti completed her undergraduate degree at MIT, her graduate work at Oxford University as a Rhodes Scholar, and her medical degree summa cum laude from Harvard Medical School as a Soros Fellow. Dr. Sabeti is a World Economic Forum (WEF) Young Global Leader and a National Geographic Emerging Explorer, and was named a TIME magazine ‘Person of the Year’ as one of the Ebola fighters. Her awards included the Smithsonian American Ingenuity Award for Natural Science, the Vilcek Prize for Creative Promise, the NIH Innovator Award, the Packard Fellowship, and an Ellis Island Medal of Honor. She has served on the MIT Board of Trustees and the National Academy of Sciences Committee on Women in Science, Medicine, and Engineering. Dr. Sabeti is also the lead singer and co-song writer of the rock band Thousand Days.
In this episode we take a closer look at the evolutionary arms race between humans and the microbes that make us sick. What does each side bring to the fight? Dr. Pardis Sabeti of Harvard University is a computational biologist who uses math and computers to look into the genomes of humans and infectious microbes to see how both humans and microbes are evolving. She was named one of TIME Magazine’s People of the Year in 2014 for her role in the fight against ebola. Links Pardis Sabeti's Lab Thousand Days on Bandcamp
2014 3월, 에볼라가 유행했을 당시, 파디스 사베티와 그녀의 연구팀은 바이러스 유전체가 어떻게 변형되고 확산했는지 연구를 진행했고, 그녀는 전 세계 바이러스 추적자들과 과학자들이 이 시간을 다투는 싸움을 함께 할 수 있도록 자신의 연구를 즉시 온라인에 공개했다. 이 토크에서 그녀는 어떻게 공동 협력체가 바이러스를 멈추는데 있어서 중요한 역할을 하고, 우리가 다음에 유행할 바이러스에 어떻게 대처해야 할 지를 보여준다. "우리는 모든 것을 공개적으로 일해고 협력해야 했습니다" 라고 사베티는 말합니다. "우리는 우리가 사는 세상을 바이러스에 의해 파괴된 곳이 아니라, 수십억명의 사람들의 생각과 마음이 함께 연합하여 빛나는 곳이라 정의되게 해야 합니다."
Quando o surto de Ebola irrompeu em março de 2014, Pardis Sabeti e sua equipe trabalharam sequenciando o genoma do vírus, entendendo como sofria mutações e se espalhava. Sabeti imediatamente publicou sua pesquisa na internet, para que rastreadores de vírus e cientistas de todos os cantos pudessem se unir a essa batalha tão urgente. Nesta palestra, Sabeti nos mostra como a cooperação aberta foi essencial para impedir a propagação do vírus... e atacar o próximo a vir. "Tivemos de trabalhar abertamente, compartilhar e trabalhar em conjunto", diz Sabeti. "Não deixemos o mundo ser definido pela destruição causada por um vírus, mas sim iluminado por milhões de corações e mentes trabalhando em unidade."
Lorsque Ebola a éclaté en mars 2014, Pardis Sabeti et son équipe ont travaillé sur le séquençage du génome du virus, afin d'apprendre comment il mutait et se propageait. Elle a immédiatement rendu ses recherches publiques, permettant à de nombreuses personnes de se joindre à cette lutte. Elle nous explique pourquoi la coopération ouverte en science est essentielle pour enrayer le virus.
Cuando el ébola estalló en marzo de 2014, Pardis Sabeti y su equipo se pusieron a trabajar para secuenciar el genoma del virus, para aprender cómo mutó y se propagó. Sabeti de inmediato publicó su investigación en línea, para que virólogos y científicos de todo el mundo pudieran unirse a la lucha urgente. En esta charla muestra cómo la cooperación abierta y participativa fue clave para detener el virus... y las amenazas que están por venir. "Hemos tenido que trabajar de forma abierta, tuvimos que compartir y tuvimos que trabajar juntos", dice Sabeti. "No dejemos que el mundo se defina por la destrucción causada por un virus, sino por la inspiración de miles de millones de corazones y mentes que trabajan unidos".
Als im März 2014 Ebola ausbrach, konnten Pardis Sabeti und ihr Team die Genome des Virus sequenzieren und somit verstehen, wie es mutiert und sich ausbreitet. Sabeti veröffentlichte ihre Arbeit sofort online, damit sich Wissenschaftler der ganzen Welt ihr in diesem dringenden Kampf anschließen konnten. In diesem Vortrag zeigt sie, dass offene Kooperation der Schlüssel dazu war, das Virus aufzuhalten ... und dem nächsten den Garaus zu machen. "Wir mussten offen arbeiten, wir mussten Ergebnisse teilen und wir mussten zusammenarbeiten," sagt Sabeti. "Die Welt sollte nicht durch die zerstörerische Wirkung eines Virus definiert werden, sondern von Milliarden Herzen und Gesitern erleuchtet werden, die zusammen arbeiten."
When Ebola broke out in March 2014, Pardis Sabeti and her team got to work sequencing the virus's genome, learning how it mutated and spread. Sabeti immediately released her research online, so virus trackers and scientists from around the world could join in the urgent fight. In this talk, she shows how open cooperation was key to halting the virus ... and to attacking the next one to come along. "We had to work openly, we had to share and we had to work together," Sabeti says. "Let us not let the world be defined by the destruction wrought by one virus, but illuminated by billions of hearts and minds working in unity."
Computational geneticist Pardis Sabeti and energy studies expert Jessika Trancik will discuss their careers and the outlook for women in science in the 21st century. Sabeti, an associate professor at Harvard and a senior associate member of the Broad Institute, and Trancik, an assistant professor in MIT’s Engineering Systems Division, are both rising stars in the research world. They will be in discussion with Rosalind Williams, the Bern Dibner Professor of the History of Science and Technology at MIT.
Dr. Pardis Sabeti has been called "the rollerblading, rock star scientist of Harvard." She invented an important new technique for genetic sequencing and looking at natural selection. Her research might even help cure Ebola. Comedians Josh Gondelman, Anna Drezen, and Emmy Blotnick learn about her work, diplotypes, and the future of genetics. Hosted by Chris Duffy. Technical direction by Kevin Brunswick.