POPULARITY
Most liver diseases are diagnosed when it's already too late. This episode explores the pros and cons of early screening, the gaps in current strategies, and how projects like LIVERAiM are aiming to change the game.Moderator: Ahmed ElsharkawyFaculty: Pere Ginès, Ian Rowe, Maja ThieleAll EASL Studio Podcasts are available on EASL Campus.Click here to see all EASL Video Podcasts on Apple Podcasts.
Black scholar and educator and American Enterprise Institute senior fellow Ian V. Rowe on why and how his Vertex schools are shaping low-income young people with moral foundations and optimism. Children in the Bronx are learning the four cardinal virtues and the personal agency which lead them into "the success sequence" that lifts kids out of poverty.Additional Resources: Book: Agency: The four point plan (F.R.E.E.) for all children to overcome the victimhood narrative and discover their pathway to power
"Pure self-reliance is a myth, but systemic change, without personal change, is hollow and dispiriting and ultimately cannot work. Its true that people need to act on their own behalf, but individuals do not developed such dogged self-determination until someone or some institution first helps them grasp that their effort is integral to achieving that goal. It is is this core conviction that allows them to endure as they encounter barriers along the way. This precondition is agency."Founder of Vertex Partnership Academies, Senior Fellow at the American Enterprise Institute, and author of Agency: The Four Point Plan (F.R.E.E.) for ALL Children to Overcome the Victimhood Narrative and Discover Their Pathway to Power Ian Rowe is our guest today and we are taking a deep dive into education. Ian and Jay are discussing how more and more kids are being told that the system is either rigged against them or they're at fault for not being able to overcome the system, how kids will start to believe those kinds of things if they hear it enough, and how it is the responsibility of the older generation to help the younger generation. Ian has dedicated his life to the service of education and we're grateful that he has chosen to share some of his journey with us on this episode of The Culture Matters Podcast.
Competencies in Civil Discourse, a series on the effectiveness of civil discourse and the skills it requires, will feature an interview with Ian Rowe, Senior Fellow at the American Enterprise Institute and cofounder of Vertex Partnership Academies in the Bronx. His schools emphasize empowering youth to develop and exercise their agency in American society. Rowe explores these ideas in his book, Agency: The Four-Point Plan (F.R.E.E.) for All Children to Overcome the Victimhood Narrative and Discover Their Pathway to Power. In this discussion, we'll focus on how rhetorical skill is essential to fostering agency in a free and civil society. Hosted on Acast. See acast.com/privacy for more information.
0:00 - Super Bowl LIX 14:08 - Super Bowl ads 31:25 - DC press corp's "Big Balls" mash-up 48:44 - Nicholas Kass, served with the U.S. Government for 31 years, most recently as Deputy Assistant Secretary of State, reacts to DOGE and the cancellation of USAID. You can follow Nick on X @NicholasSKass 01:08:20 - Steven Bucci, visiting fellow in The Heritage Foundation’s Allison Center for Foreign Policy Studies, looks at what is feasible in Gaza and what can be done with displaced Gazans 01:26:26 - Ian Rowe, founder of Vertex Partnership Academies, on the messages for black youth from the Super Bowl ads and halftime show. For more on Vertex Partnership Academies vertexacademies.org 01:44:22 - Suburban Values 02:03:59 - Dennis Kneale, former senior editor at the Wall Street Journal and managing editor of Forbes, shares details from his new book The Leadership Genius of Elon Musk. Dennis is also host of the “What’s Bugging Me” podcast on the Ricochet networkSee omnystudio.com/listener for privacy information.
I’m reposting an episode of the Invisible Men podcast, hosted by Ian Rowe and Nique Fajors. They had me on to talk about Late Admissions, the bias and development narratives, and a lot more. Ian and Nique have a stellar lineup of guests who are having the important conversations about race in America, so check […]
Much like other governmental agencies, child welfare systems are long overdue for a digital upgrade. But how can we ensure the technological tools implemented truly equip caseworkers and supervisors to meet the needs of children and families?This week, Naomi and Ian are joined by Sixto Cancel, the founder and CEO of Think of Us, a tech nonprofit working to reform the child welfare system in the US. Inspired by his own story in foster care, where one, outdated sentence in his case file determined the trajectory of his time in the system, Sixto founded Think of Us to improve the tech landscape of the foster care system. From the need to incorporate assistive AI into case management to improving federal incentives to encourage innovation, Sixto discusses the key areas in need of reform. Resources• Taking Child Welfare into the 21st Century | Naomi Schaefer Riley, Ian Rowe, and Greg McKay• Big Data Can Save Kids | Naomi Schaefer Riley• Think of Us | Sixto CancelShow Notes• 00:52 | What is the technology landscape of child welfare, and are the systems being used up to date?• 03:07 | What is the origin of your name, Sixto Cancel? • 04:06 | What about your story led you down this path to work toward better experiences for youth in foster care?• 06:38 | What could systems be doing differently to take into account all of the options for foster youth?• 09:28 | How are you now using virtual support services for youth getting ready to age out of the system?• 12:15 | Many child welfare agencies contract with different providers to meet their needs. How is this currently working, and could it be more efficient?• 15:32 | Why was the federal funding you secured ineffective to upgrade the technology systems within child welfare agencies?• 17:08 | What would be the better approach? Should the federal government still be involved, or would that run the same risk of having just one large entity dominating the space and discouraging innovation?• 20:05 | Are you planning to expand the direct service component of your organization?• 21:22 | Thinking about the data you've collected so far, what would say is the biggest mismatch between what people need and what is being offered to them?
Technological innovations are often sold to the public as ways to make life easier. But what if the increasing prevalence of technology in our lives is actually crowding out human experiences that are integral to children's development and well-being?This week, Naomi and Ian are joined by AEI Senior Fellow Christine Rosen to discuss her new book, The Extinction of Experience. Christine argues that the unmitigated push to integrate technology into all areas of life can be particularly harmful for children, who could be missing out on fundamental human experiences that help them grow. She highlights how even simple practices like learning cursive, or more significant milestones like dating—without the medium of screens—play a fundamental role in shaping who children become as adults. Contrary to tech moguls like Elon Musk who want to form new human communities on other planets, Christine believes we have a responsibility to find solutions that make life on earth a good one for children. Making the active choice to cut out technology from certain areas of our lives could be a good place to start. Resources• The Extinction of Experience: Being Human in a Disembodied World | Christine Rosen• The Lost Art of Waiting | Christine Rosen• Katharine Birbalsingh on Banning Smartphones from Schools | Naomi Schaefer Riley, Ian Rowe, and Katharine BirbalsinghShow Notes:• 01:13 | When did you first start noticing the negative impacts screens were having on kids?• 03:11 | Does it bring you some comfort that there is a growing movement to remove cell phones from schools?• 05:14 | What are some of the individual experiences we are losing because of technology? Are there some experiences that are alright to replace?• 08:00 | How has technology affected dating and the romantic lives of young people?• 10:03 | Can we recapture the tradition of having ‘forced' human interaction in spaces like churches, schools, and homes?• 12:36 | What can you tell us about the individuals and companies who are making these technologies?• 15:19 | Figures like Elon Musk have resorted to colonizing new planets as a solution to some of our human problems. Is this the right response? How would you respond?• 18:08 | What are the chances that a child who has been raised with so much technology will be able to dig themselves out of this?• 20:55 | Is there a role for faith and religious institutions in all of this?
We are in the Third Qualifying of the FA Trophy this weekend. The Step 3 clubs are the big boys and big scalps to be taken; 88 of those clubs and the 40 clubs from Step 4 have progressed from the last round. Phil Annets is on hand with some thoughts and insight wearing his @FATrophyFacts hat. Our manager this week, is another at a club built on camaraderie and a place people want to be. Ian Rowe has been the gaffer of Sporting Khalsa for 10 years now but the club is more than just the men's first team, it's very much about the people, as Ian explains. Helping with the weekly news round-up Jon Couch is back. Another packed issue of The Non League Paper ahead but first we discuss the FA Cup draw, clubs in trouble and of course, more managerial moves.
In this week's Dissidents Podcast, Jennifer Richmond and Winkfield Twyman, Jr. speak with Ian Rowe. Ian recently wrote a review of their book (Letters in Black and White: A New Correspondence on Race in America), which he entitled Three Cheers for Colorblindness. Wink and Jen, much like they start their book, start the conversation with Ian by getting his “origin story,” i.e. what makes you tick?? The author of Agency: The Four Point Plan (F.R.E.E) for All Children to Overcome the Victimhood Narrative and Discover Their Pathway to Power, shares with us his upbringing and family foundations, that leads into the discussion of Wink's ancestral ties to America's founding father, George Washington. With such rich origin stories, why do we reduce individuals to the singular characteristic of race (the single drop rule)? The dearth of nuance and complexity that is denied when we tell our children that “blackness is oppression, nothing else matters,” constrains us from a full life of self-determination, agency and the dignity of achievement. At the end of the day, we are all cousins and recognizing that common humanity is the best path forward. Podcast Resources: Three Cheers for Colorblindness, Ian Rowe https://rlo.acton.org/archives/125823-three-cheers-for-color-blindness.html Agency: The Four Point Plan (F.R.E.E) for All Children to Overcome the Victimhood Narrative and Discover Their Pathway to Power, Ian Rowe https://www.amazon.com/Agency-F-R-Children-Victimhood-Narrative/dp/B0C3WQCYKF/ Letters in Black and White: A New Correspondence on Race in America, Winkfield Twyman, Jr & Jennifer Richmond https://www.amazon.com/Letters-Black-White-Correspondence-America/dp/1634312368/ White Jamaicans, Winkfield Twyman, Jr. https://twyman.substack.com/p/white-jamaicans Please Resign Harvard University President Claudine Gay, Winkfield Twyman, Jr. https://twyman.substack.com/p/please-resign-harvard-university Liberalism in Practice Panel Discussion: Lessons from Harvard after the Claudine Gay Affair, The Institute for Liberal Values https://youtu.be/uMzFvMPHeBU?si=yHxhR7p3dlBWJvdY Matisyahu https://en.wikipedia.org/wiki/Matisyahu Vertex Academies https://www.vertexacademies.org/ FREE Initiative https://www.aei.org/free/ A Better Chance (ABC Program) https://abetterchance.org/
The Supreme Court's decision to strike down affirmative action in college admissions last year has ushered in a new era of uncertainty and debate in higher education. As the first post-affirmative action enrollment numbers emerge, society is witnessing a shift in the demographic makeup of incoming classes, with discrepancies between different socioeconomic groups. Ian Rowe from American Enterprise Institute challenges us to create a fair and inclusive higher education system that provides opportunities for all students to reach their full potential.
Dig into Thursday’s headlines with Boyd Matheson! Ian Rowe joins Boyd to discuss what the data is showing a year after affirmative action was struck down by the Supreme Court. Delve into the spending negotiations happening in Congress with Kellie Meyer. Jenet Jacob Erickson breaks down the data on what reality is for religious women, especially those belonging to the Church of Jesus Christ of Latter-day Saints. Jay Evensen unravels the narrative that inflation is caused by greed and More!
We're starting off the summer break with #10 of our Top 10 Season 1 episodes. Ever wondered how personal agency can transform lives? In Episode 11 of The KindlED Podcast, Kaity and Adriane welcome author and educational expert Ian Rowe. Ian, a senior fellow at the American Enterprise Institute, co-founder of Vertex Partnership Academies, and CEO of Public Prep, shares his inspiring story of personal 'coming of agency.' ABOUT THE GUEST:Ian Rowe is a senior fellow at the American Enterprise Institute, where he focuses on education and upward mobility, family formation, and adoption. Mr. Rowe is also the cofounder of Vertex Partnership Academies, a new network of character-based International Baccalaureate high schools opening in the Bronx in 2022; the chairman of the board of Spence-Chapin, a nonprofit adoption services organization; and the cofounder of the National Summer School Initiative. He concurrently serves as a senior visiting fellow at the Woodson Center and a writer for the 1776 Unites Campaign.Until July 1, 2020, Mr. Rowe was CEO of Public Prep, a nonprofit network of public charter schools based in the South Bronx and Lower East Side of Manhattan. Before joining Public Prep, he was deputy director of postsecondary success at the Bill & Melinda Gates Foundation, senior vice president of strategic partnerships and public affairs at MTV, director of strategy and performance measurement at the USA Freedom Corps office in the White House, and cofounder and president of Third Millennium Media. Mr. Rowe also joined Teach for America in its early days.Mr. Rowe has been widely published in the popular press, including in the New York Post, The Wall Street Journal, and the Washington Examiner. He is often interviewed on talk radio programs. With his forthcoming book “Agency” (Templeton Press, May 2022), Ian Rowe seeks to inspire young people of all races to build strong families and become masters of their own destinies.RELEVANT LINKS:BLACK MEN MAKING IT IN AMERICA: The Engines of Economic Success for Black Men in AmericaGot a story to share or question you want us to answer? Send us a message!About the podcast:The KindlED Podcast explores the science of nurturing children's potential and creating empowering learning environments.Powered by Prenda, each episode offers actionable insights to help you ignite your child's love of learning today. We'll dive into evidence-based tools and techniques that kindle young learners' curiosity, motivation, and well-being. Got a burning question?We're all ears! If you have a question or topic you'd love our hosts to tackle, please send it to podcast@prenda.com. Let's dive into the conversation together!Important links:• Want more KindlED content?• Connect with us• Subscribe to The Sunday SparkInterested in starting a microschool?Prenda provides all the tools and support you need to start and run an amazing microschool. Create a free Prenda World account to start designing your future microschool today ➡️ Start My Microschool
This conversation comes from our coverage of The EASL Congress, 2023, when Sven Francque and Ian Rowe joined Jörn Schattenberg and Roger Green to consider primary care screening at the top of the Clinical Care Pathway. The original conversation had a robust write-up: Ian starts this conversation by pointing to unmet needs in the primary care setting for disease identification. He refers to a related presentation of interest from Vincent Wong titled A clinical care pathway to detect advanced liver disease in patients with type 2 diabetes through automated fibrosis score calculation and electronic reminder messages: a randomized controlled trial. Ian suggests that this study proves both the value of working to identify more patients and the considerable amount of work remaining in this area. The group goes on to discuss what the implications of this study are for treatment in primary care both now and into the future of patient care. In particular, Jörn elucidates the value of FIB-4 not only as a screening tool for liver-related outcomes, but also as a predictor of cardiovascular risk and all-cause mortality. Secondly, Jörn notes that when a NASH therapy becomes available, "the granularity of picking up those patients will be higher" and physicians will be more motivated to take action provided that they have both a screening tool and available treatment to prescribe. This leads to discussion around the differences between hepatology and private medicine practices and management of a population-level disease. Ian raises the question around how frequent should testing be performed in the primary care setting for different pathways.
This conversation focuses on what panelists see as a key (and somewhat unusual) benefit of Rezdiffra: that having a prescription drug for MASH creates a better environment for discussing lifestyle intervention and improving overall patient adherence with diet and exercise. This conversation focuses on the impact of having a drug on getting patients to comply with lifestyle interventions. Zobair Younossi starts by noting that, historically, it has been "very difficult" to institute successful lifestyle interventions because patients "are not used to thinking about lifestyle as a prescription." Now, providers can counsel patients to adhere to a regimen that includes medication and lifestyle changes. Jörn Schattenberg notes that Rezdiffra is indicated in the label as an adjunct to diet and exercise, which is common wording for most metabolic drugs. Zobair agrees but notes that this is still difficult to achieve in practice. One example: in the US, not everyone can comply with the idealized Mediterranean diet. As he notes, diet recommendations must be geographically and culturally relevant.I note that in my 25 years of marketing research, one thing I learned was that physicians feel they "have nothing" when all they can offer patients is lifestyle modification. With a drug in the discussion, the provider can "flip the script" to make lifestyle intervention adjunctive to the drug. Jeff McIntyre points out specifically that having Rezdiffra to prescribe will help reduce stigma by "medicalizing" the recommendation to lose weight and add exercise. In effect, Jeff says, this takes the onus off the patient to feel responsible for their own disease. Zobair discusses a recent publication from the Global MASH Council on the impact of stigma. At this point, Laurent Castera joins the conversation. He adds the thought that having a drug to prescribe will increase interest among primary care providers. He also notes the importance of the label coming without a biopsy requirement, "a very important message to convey." The conversation ends with Ian Rowe sharing his concern that it will be "quite difficult" to differentiate patients living with advanced fibrosis patients from those living with cirrhosis.
Last Thursday, March 14, Rezdiffra (resmetirom) became the first MASH drug approved in the US. A global panel of Key Opinion Leaders convenes to discuss their excitement about this approval, the opportunities it will create and some of the (largely manageable) challenges it might present. 00:00:00 - Surf's Up: Season 5 Episode 6 Opening introduction from an excited, enthusiastic panel, including brief quotes taken directly from the episode discussion.00:05:02 - GroundbreakersEach panelist shares one piece of good news from the previous week.00:08:15 - Waiting for news and initial reactionsPanelists describe their moods throughout the day on March 14 and reactions when word of the approval came from FDA. They describe feeling varying degrees of trepidation as the day progressed without word from the agency, replaced by excitement and joy at the final announcement. 00:14:30 - Specific patients to target or avoidPanelists describe the patients they expect to prescribe Rezdiffra for first (now for the US, when it becomes available for EMA). The group aligns on the benefits for F3 and F2 patients (the two groups listed on the label) but shares concerns about accurate identification of F3 vs. compensated cirrhosis.00:17:07 - Impact on explaining lifestyle interventionsZobair Younossi notes the historical difficulty of getting patients to view lifestyle modification as a specific prescription to be followed. He, Roger and Jeff all makes points to suggest that the combination of drug + lifestyle modification will be easier to explain to patients. 00:26:32 - Staging and screening patients using NITs Laurent Castera joins the conversation as the topic switches to proper use of NITs. Previously, Jörn Schattenberg and Ian Rowe touched on challenges in deciding which patients have F3 fibrosis vs. early stage cirrhosis. Now the group explores the relative value of different strategies for qualifying patients. One key: while FIB-4 is an efficient screening test in largely negative populations, it produced a high level of false positives in specialty practices.00:33:50 - How to educate providers Roger points out that individual providers will conduct individual "clinical trials" in their own practices. This makes provider education on proper use critical to launch success. Louise Campbell commends Madrigal for the education pathway they laid out during the webcast. Jeff discusses the important role patients must play. 00:39:06 - Finding the initial patientsApropos of education, Zobair points out that most early patients will be found in GI practices. Jeff points out that these patients are already in the system and can be easily identified.00:43:12 - Why Rezdiffra's strong safety profile matters so muchPanelists agree that Rezdiffra's safety profile alleviates some concern that a well-meaning provider might prescribe for a patient with compensated cirrhosis due to inadequacy of current tests.00:48:39 - Suggested takeaways for industry Panelists suggest that industry learn from the large sample sizes and thoughtful use of NITs found in the Rezdiffra trial protocols.00:52:20 - FDA and NITs Louise asks how important FDA's two-day NIT workshop last year was in the agency not requiring biopsy prior to prescribing. Zobair says agency officials are moving slowly down a path toward greater acceptance.00:53:53 - Closing ThoughtsEach panelist shares a closing thought. The topics vary widely.01:01:06 - Question of the WeekThe question is what impact Rezdiffra's approval will have on individuals' day-to-day work.01:01:47 - Business reportNews on audience metrics, future episodes and why there will be no Vault conversation this week
This conversation explores the challenges with using the current non-invasive tests (NITs) to diagnose patients with F2/F3 advanced MASH fibrosis. If tests today cannot achieve the requisite level of precision, panelists explore other ways to define patient targets. Roger Green starts by recalling that in a recent episode (Season 5 Episode 2), Jeff McIntyre suggested that in the US, the initial patient population may be as small as a few hundred thousand people. Ian Rowe states that current tools are incapable of placing these patients in a narrow diagnostic or therapeutic window. Jörn Schattenberg takes a "pragmatic" approach to defining the patient he is certain to treat; test results are a small part of his calculus. Naim Alkhouri shifts the discussion to focus on VCTE cutoff points for cirrhosis. The interplay between Naim and Ian suggests that different practices and guidelines carry with them different cutoffs. Jörn expresses gratitude that the can watch the US and learn from that experience. He notes the tension between wanting a cost-effective system and large numbers of patients clamoring for the new medicine. The need to rule some patients out is obvious, the way to do so is challenging. Asking, "What can we do besides scan" or use conventional tests, Naim discusses some newer options, starting with the metabolomics-based MASEF score discussed in Season 4 Episode 39. He also mentions the LiverFast test. Jörn describes factors that can render a test inappropriate for a particular patient. Louise suggests the right test will depend on the specific question the provider is trying to answer.
This conversation focuses more tightly on the specific challenges with the current approaches that use NITs to diagnose and stage advanced MASH fibrosis and explores several newer options and ways of thinking about the challenge.Roger Green notes that recent papers discuss the failure to predict accurately with FIB-4. He asks how we can improve predictive performance. Louise Campbell notes some specific challenges, after which Jörn Schattenberg praises John Dillon's work in automating lab detection algorithms. He also reiterates his view that repeat testing will be pivotal in good test protocols. Ian Rowe rejoins the conversation (from a faulty Internet connection) to comment that our inability to stage patients reliably will lead to government payers like NHS believing that they will need biopsy to stage patients accurately and treat them cost-effectively. Jörn says Germany will work differently and if EMA approves it, it will launch in Germany.Roger asks about new tests on the horizon and specifically whether there is sufficient improvement in diagnosis, staging or treatment. He refers specifically to MASEF and Naim Alkhouri's earlier comments about four scan vendors at his conference. Ian says there are tests that can rise to this task, but they are not produced in sufficient quantity and cost too much to become a first-line option. Naim notes that the most exciting tests are a couple of years away. Ian returns to Jörn's earlier point about the value of sequential testing vs an individual test. Louise suggests that device size will be pivotal for primary care.
This conversation touches on two important subjects: the impact of different potential resmetirom prices on the size and structure of the treatable MASH population, and the impact GLP-1s are having (and will have) on clinical trial recruitment and basic patient treatment. It starts with Naim Alkhouri expressing concern over the $39-52K price he has heard for resmetirom, which ICER has deemed cost-effective. He mentions another paper that says a price of $19,000 would be cost-effective. To Naim, this magnifies a question that is already quite widely considered: when to prescribe resmetirom vs. a GLP-1 agent. He discusses some patient factors that might go into his decision. Naim describes ways that GLP-1 use, which can be sporadic or episodic, is affecting clinical trial recruitment. Ian Rowe discusses the current use of GLP-1s in the UK and suggests that if the price for resmetirom is high enough, GLP-1s will receive significant use. Naim Alkhouri shifts direction slightly, from discussing current GLP-1s to exciting recent clinical trial report. He focuses on two: survodutide from Boehringer Ingelheim and efruxifermin from Akero Therapeutics. Recent exciting results from BI and Akero suggest to Naim and others that the future for drugs is bright. Ian Rowe anticipates a significant amount of co-prescription of GLP-1s and resmetirom in this population. GLP-1s have already demonstrated clear cardiovascular, weight loss, and HbA1c-lowering benefits. To Ian, that creates sufficient motivation to prescribe GLP-1s to multimorbid patients with diabetes, obesity and most likely MASLD or MASH. To him, the price of resmetirom will have a tremendous impact on how often UK physicians rely on GLP-1s alone.
This conversation explores why proper use of non-invasive tests (NITs) will play a pivotal role in increasing the number of patients diagnosed and treated for MASH. It becomes particularly pivotal if, as expected, the first MASH drug is approved later this month. Roger Green starts this conversation by describing why he considers NIT use and adoption one of the two pivotal patient treatment issues for 2024. Jörn Schattenberg notes that he has not received any referrals from PCPs or endocrinology based on elevated FIB-4, which would happen if enough front-line treaters were adopting the new clinical care pathways. Educational efforts have begun, but do not seem to be changing behavior yet. As Jörn puts it, "We're still preaching, and I haven't seen it in much activity."Naim Alkhouri states that his experience is the same as Jörn's. He reminds us that we covered some of these issues in a 2023 end-of-year conversation (S4 E50.3). He reiterates his concern with FIB-4 as a standalone first-line test and states his preference for combining it with an in-office scan. He comments that at the recent Desert Liver Conference, four companies displayed these devices, each with a different price point and convenience factor. Ian Rowe describes the British experience as being different: "every patient with elevated ALT in the context of metabolic risk factors has a FIB-4 and now has a FibroScan." His biggest concern is that tests are insufficiently precise. If we have top-end and bottom-end cutoffs, he fears, "you're going to end up excluding a lot of patients who would be potentially eligible for treatment."
In 2024, the two major areas for change in diagnosing and treating MASH are new drug approval and changes in use of NITs. Naim Alkhouri and Ian Rowe join Jörn Schattenberg, Louise Campbell and Roger Green to consider what might change with NITs and how having an approved drug might change thinking on this issue.00:00:00 - Surf's Up: Season 5 Episode 5Opening introduction, including brief quotes taken directly from the episode discussion.00:02:36 - Introduction and GroundbreakerPanelists congratulate Naim on the recent, highly successful Desert Liver Conference. In the groundbreaker, each panelist shares one piece of good news from the previous week.00:06:36 - Why Focus on NITs?Roger describes why he considers this issue worthy of an episode. Naim and Jörn both state that they have received no referrals from PCPs or endocrinology based on elevated FIB-4 tests. Ian notes that the UK has guidelines and pathways built into some protocols; these make it challenging to stage a patient as F2 vs F3 vs early compensated cirrhosis.00:13:06 - NITs and treating F2/3 MASH patients Ian says that current tools are incapable of defining the small nitial target patient population Jeff McIntyre suggested in Season 5 Episode 2. patients clearly enough to place them in a narrow diagnostic or therapeutic window. Jörn takes a "pragmatic" approach to defining the patient he is certain to treat; test results are a small part of his calculus. Naim shifts the target patient to focus on VCTE cutoff points for cirrhosis. There is no clear cutoff. 00:18:45 - Tests worth using beyond the widely discussed options Asking "What can we do besides scan" or use conventional tests, Naim discusses some the new blood-based tests. Jörn describes factors that can render a test inappropriate for a particular patient. Louise suggests the right test will depend on the specific question the provider is trying to answer. 00:22:59 - Improving on FIB-4Roger notes that recent papers discuss failure to predict accurately with FIB-4. In the conversation that follows, panelists agree that automating test results and using a series of tests instead of a single event will both have real value. 00:28:27 - New Devices and Blood-Based Tests for Use in OfficeRoger asks about new tests on the horizon and specifically whether there is sufficient improvement in diagnosis or treatment. Naim notes that the most exciting tests are a couple of years away. Ian returns to Jörn's earlier point about the value of sequential testing vs an individual test. Louise suggests that device size will be pivotal for primary care. 00:35:30 - Impact of Resmetirom PriceNaim expresses concern over the $39-52K price he has heard for resmetirom. Roger states that price reflects size of target market. At that point, the discussion veers toward factors that drive drug prices higher.00:40:22 - Impact of GLP-1s on treatment and resmetiromRoger asks the group what the impact of consumer-driven GLP-1 use is likely to be on US prescribing of MASH drugs. Ian discusses use of GLP-1s in the UK and suggests that if the price for resmetirom is high enough, GLP-1s will receive significant use. Recent exciting results from BI and Akero suggest to Naim and others that the future for drugs is bright. 00:47:16 - Final questionThis entails Roger summarizing what he has heard in the conversation and testing for confirmation or correction. It goes fast and covers significant ground. 00:53:26 - Question(s). of the Week The question is what else will change, besides prescribing, once a drug is improved and what the industry can to do optimize change.00:54:06 - Business ReportNews on audience metrics, the upcoming Question of the Week, future episodes and this week's Vault co
Welcome to "CURE America with Star Parker," where insightful discussions and thought-provoking conversations take center stage at the headquarters of AEI - American Enterprise Institute. In this exclusive show, hosted by Star Parker, President of the Center for Urban Renewal and Education (CURE), delves into the pressing issues facing black Americans today. This episode, titled "The State of Black Progress," is a recording of a pre-release tome that took place during Black History Month, exploring the history and current state of affairs for black Americans in key areas such as health care, education, housing, and economic development. Joining Star Parker in this crucial conversation are distinguished guests who bring a wealth of knowledge and expertise. AEI scholars Ian Rowe and Howard Husock, along with Galen Institute President Grace-Marie Turner, share their insights on how the right set of policies and incentives, free from government interference, can pave the way for genuine progress for Americans of all races. The forum is moderated by CURE's Vice Chairman, T.W. Shannon, ensuring a dynamic and engaging discussion. "CURE America with Star Parker" presents a unique and comprehensive exploration of the issues affecting black Americans today. Don't miss the opportunity to be part of this enlightening experience as we navigate the complexities of policy, progress, and community well-being. Tune in to join the conversation that is shaping the future of America.
Our first conversation focusing on the new MASLD nomenclature surfaces as part of our coverage of the EASL Congress 2023. Hepatology researchers and key opinion leaders Sven Francque and Ian Rowe joined Jörn Schattenberg and Roger Green to discuss the value of the new nomenclature and its current and anticipated impact on their practices. This conversation focuses on the outcome of the nomenclature process, a three-stage Delphi process that produced new names and classifications for what had previously been known as fatty liver disease and henceforth will be known as steatotic liver disease (SLD). Sven, who was actively involved in the entire exercise, gives a concise summary of the process by which the new classifications were developed and how the new terminology will work. The rest of the conversation focuses on three issues.Excitement that we will now have the opportunity to study patients whose disease has both metabolic and alcohol-based components.The processes by which the three clinicians, Sven, Ian and Jörn are starting to share the new structure with their patients with varying degrees of success. One interesting observation emerges here from Sven: the English language terms do not translate equally into Dutch, so there is a patient advocate-led effort to create a new set of terms in Dutch.Roger raises concerns about implementation planning for the new nomenclature. One concern is around the possible impact on drug or diagnostic development and the other is about the kinds of communication issues covered in earlier episodes. Sven, who again worked more closely on the process, states with confidence that the change will not have an impact on drug or diagnostic trials. Subsequent events prove Sven right.
Every child is capable of being an agent of their own uplift provided they are given the resources to inform the decisions that will make them successful adults. Ian Rowe, Sr. Fellow at the American Enterprise Institute discussed four factors that are crucial for children to overcome the victimhood narrative and discover their pathway to power: family, religion, education, and entrepreneurship.Support the show
0:00 - SD Gates: CPS needs more $$ for 5K migrant students 11:43 - Javier Milei at WEF: The West is in trouble because of, well, you here in Davos 29:39 - Jamie Dimon from Davos: I wish Dems would be more careful in how they talk about MAGA 44:49 - “Bipartisan Dignity Act” – Rep. Maria Gonzalez (R-FL) & Rep. Hillary Scholton (D-MI) 01:04:38 - Ian Rowe, senior fellow at the American Enterprise Institute and author of Agency: The Four Point Plan (F.R.E.E.) for ALL Children to Overcome the Victimhood Narrative and Discover Their Pathway to Power, commemorates national school choice week by calling out Illinois backwards education policies. Ian will be sitting down for a conversation with Wirepoints' Ted Dabrowski this Monday, Jan 22, at 7 pm - Loyola Academy McGrath Family Performing Arts Center - 1100 Laramie Avenue, Wilmette - For more details and to register Click Here 01:23:44 - The Spectator's Washington editor, Amber Duke,. Amber is also the author of The Snowflakes' Revolt: How Woke Millennials Hijacked American Media 01:36:15 - Tom Homan, former Acting Director of U.S. Immigration and Customs Enforcement, asks Why is Biden stripping ICE of resources during worst border crisis in U.S. history? 01:50:10 - Conrad Black, Lord Black, Baron Black of Crossharbour – businessman, writer, former newspaper publisher, discusses his new book The Political and Strategic History of the World, Vol I: From Antiquity to the Caesars, 14 A.D. For more from Lord Black, check him out on X @ConradMBlackSee omnystudio.com/listener for privacy information.
On this episode of Our American Stories, Ian Rowe took full responsibility for what he believed was right. He sized up the assumption that his public school becoming all black in one year would make it worse - and committed 100% to staying there to make it the very best. Support the show (https://www.ouramericanstories.com/donate)See omnystudio.com/listener for privacy information.
This week on The Learning Curve, guest co-hosts Prof. Albert Cheng of the University of Arkansas and Ian Rowe,the founder of Vertex Partnership Academies in NYC, interview Dr. Carol Swain, an award-winning political scientist. Dr. Swain discusses her background growing up in rural Virginia, experiences with racial discrimination and segregation in K-12 schooling, and changes […]
This week on The Learning Curve, guest co-hosts Prof. Albert Cheng of the University of Arkansas and Ian Rowe, the founder of Vertex Partnership Academies in NYC, interview Dr. Carol Swain, an award-winning political scientist. Dr. Swain discusses her background growing up in rural Virginia, experiences with racial discrimination and segregation in K-12 schooling, and changes in the intellectual climate on college campuses. She shares the role of faith in promoting literacy and justice, the legacies of MLK and Malcolm X, the 1619 Project, her work with 1776 Unites, and her belief in the importance of public intellectuals speaking their minds.
Ian Rowe, an American Enterprise Institute senior fellow and cofounder of the Bronx-based Vertex Partnership Academies, joins Hoover senior fellows Niall Ferguson and John Cochrane to discuss the future of public education and charter schools' role in the quest for better outcomes. What lessons does a virtues-based public charter high school in New York City offer to the ideal of education as a path to life success? Ian Rowe, an American Enterprise Institute senior fellow and cofounder of the Bronx-based Vertex Partnership Academies, joins Hoover senior fellows Niall Ferguson and John Cochrane to discuss the future of public education and charter schools' role in the quest for better outcomes. After that: Niall and John weigh in on the potential for economic turmoil in a time of global instability; a hypothetical outsider as House Speaker; plus their like and dislike of the Olympic Games.
In this episode, Tudor interviews Ian Rowe, a senior fellow at the American Enterprise Institute and founder of Vertex Partnership Academies. They discuss the impact of social media on students, the importance of parental involvement, and the strategies implemented in Rowe's charter school to combat these issues. Rowe emphasizes the importance of virtues like courage, justice, temperance, and wisdom in education, and the role of religion, family, and entrepreneurship in breaking the cycle of disadvantage. He also rejects the idea of victimhood, advocating for personal agency and determination in students. The Tudor Dixon Podcast is part of the Clay Travis & Buck Sexton Podcast Network - new episodes debut every Monday, Wednesday, & Friday. For more visit TudorDixonPodcast.comFollow Clay & Buck on YouTube: https://www.youtube.com/c/clayandbuckSee omnystudio.com/listener for privacy information.
In this episode, Tudor interviews Ian Rowe, a senior fellow at the American Enterprise Institute and founder of Vertex Partnership Academies. They discuss the impact of social media on students, the importance of parental involvement, and the strategies implemented in Rowe's charter school to combat these issues. Rowe emphasizes the importance of virtues like courage, justice, temperance, and wisdom in education, and the role of religion, family, and entrepreneurship in breaking the cycle of disadvantage. He also rejects the idea of victimhood, advocating for personal agency and determination in students. The Tudor Dixon Podcast is part of the Clay Travis & Buck Sexton Podcast Network - new episodes debut every Monday, Wednesday, & Friday. For more visit TudorDixonPodcast.comSee omnystudio.com/listener for privacy information.
In this episode, Tudor interviews Ian Rowe, a senior fellow at the American Enterprise Institute and founder of Vertex Partnership Academies. They discuss the impact of social media on students, the importance of parental involvement, and the strategies implemented in Rowe's charter school to combat these issues. Rowe emphasizes the importance of virtues like courage, justice, temperance, and wisdom in education, and the role of religion, family, and entrepreneurship in breaking the cycle of disadvantage. He also rejects the idea of victimhood, advocating for personal agency and determination in students. The Tudor Dixon Podcast is part of the Clay Travis & Buck Sexton Podcast Network - new episodes debut every Monday, Wednesday, & Friday. For more visit TudorDixonPodcast.comSee omnystudio.com/listener for privacy information.
Ian Rowe has proved it. The longtime head of Public Prep – a wildly successful charter school system in New York City – Ian has discovered surprising ways to empower kids who society ignores and overlooks. Let's see what Ian believes about the principles and practices that enable any kid to achieve anything. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast... Spotify: https://open.spotify.com/show/7eAkovs... Substack: https://believepodcast.substack.com/ Follow Believe!: Twitter: https://twitter.com/Believe_Pod Instagram: https://www.instagram.com/believe_pod/ Follow Doug DeVos: Twitter: https://twitter.com/Doug_DeVos Instagram: https://www.instagram.com/doug.devos Facebook: https://www.facebook.com/dougdevosamway/ LinkedIn: https://www.linkedin.com/in/doug-devos For show notes and more, visit https://thebelievepodcast.com/.
On today's Remnant—which happens to be more than a year in the making—Jonah's joined for the first time by Ian Rowe, a senior fellow at AEI and the author of Agency (2022), which explores how young people can build strong families and take control of their destiny. Much of their conversation focuses on one of Ian's primary interests, the success sequence, and whether it's still valid in modern America. But plenty of wonkish musings are also mixed in on the importance of stable marriages, the achievement gap in education, and the values we should impart to our children. Show Notes: -Ian's page at AEI -Ian's book, Agency -AEI's special forum on the 60th anniversary of the March on Washington -The Remnant with Thomas Sowell -Ian: “The Game of Life” -Ian: “A Vision of Black Success” Learn more about your ad choices. Visit megaphone.fm/adchoices
The importance of a strong family foundation and equal access to quality education is crucial to the success of young people. Dr. Carson and Ian Rowe discuss the urgent need to address disparities in education and opportunity in the United States, particularly in low-income areas and inner cities. Rowe argues that race-based affirmative action is not the root cause of these disparities, but rather the lack of preparation and support for students before they even enter school. He emphasizes the importance of education and family formation in empowering America's children and promoting upward mobility. Rowe highlights the significance of open adoption in empowering women facing unwanted pregnancies and forming strong families for vulnerable children. Ian Rowe is the author of “Agency” which seeks to inspire young people of all races to build strong families and become masters of their own destiny.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In Episode 11 of The KindlED Podcast, hosts Kaity and Adriane welcome author and educational expert Ian Rowe. Ian, a senior fellow at the American Enterprise Institute, co-founder of Vertex Partnership Academies, and CEO of Public Prep, shares his inspiring story of personal 'coming of agency.' ABOUT THE GUEST:Ian Rowe is a senior fellow at the American Enterprise Institute, where he focuses on education and upward mobility, family formation, and adoption. Mr. Rowe is also the cofounder of Vertex Partnership Academies, a new network of character-based International Baccalaureate high schools opening in the Bronx in 2022; the chairman of the board of Spence-Chapin, a nonprofit adoption services organization; and the cofounder of the National Summer School Initiative. He concurrently serves as a senior visiting fellow at the Woodson Center and a writer for the 1776 Unites Campaign.Until July 1, 2020, Mr. Rowe was CEO of Public Prep, a nonprofit network of public charter schools based in the South Bronx and Lower East Side of Manhattan. Before joining Public Prep, he was deputy director of postsecondary success at the Bill & Melinda Gates Foundation, senior vice president of strategic partnerships and public affairs at MTV, director of strategy and performance measurement at the USA Freedom Corps office in the White House, and cofounder and president of Third Millennium Media. Mr. Rowe also joined Teach for America in its early days.Mr. Rowe has been widely published in the popular press, including in the New York Post, The Wall Street Journal, and the Washington Examiner. He is often interviewed on talk radio programs. With his forthcoming book "Agency" (Templeton Press, May 2022), Ian Rowe seeks to inspire young people of all races to build strong families and become masters of their own destinies.RELEVANT LINKS:
Author, Educator and Entrepreneur Ian Rowe runs charter schools in the Bronx. His perspective on Affirmative Action and the recent SCOTUS decision may surprise you. He will definitely inspire you!See omnystudio.com/listener for privacy information.
It seems Democrats are confident that racial preferences are the only way for Black Americans to succeed. Our all-American guest Ian Rowe disagrees. Why's he so sure? Because he's sees acheivement everyday in his charter schools in the Bronx. He covers why the left's prescriptions to equality is wrongheaded and harmful, along with why his are working. Rob, James and Steve (filling in for the hookey-playing Peter Robinson) get into all sorts of trouble when the educator's away... literal high crimes, misdeanors and other bad behavior.
It seems Democrats are confident that racial preferences are the only way for Black Americans to succeed. Our all-American guest Ian Rowe disagrees. Why’s he so sure? Because he sees stellar achievement everyday in his charter schools in the Bronx. Ian covers why the left’s prescriptions to equality are wrongheaded and harmful, along with why […]
This is an abbreviated version of The Michael Medved Show. To get the full program, plus premium content, become a subscriber at MichaelMedved.com
Happy Father's Day! For today's episode, a conversation about fatherhood with three dads who have thought a lot about parenthood, masculinity and being a dad in a world stripped of convention. Richard Reeves is a Senior Fellow at the Brookings Institution, and the author of the book Of Boys and Men about why boys and men are falling behind in so many aspects of American life. Ryan Holiday is a writer, bookstore owner, Daily Stoic and Daily Dad podcast host. Ian Rowe is a Senior fellow at American Enterprise Institute where he works on issues surrounding education and upward mobility, family formation, adoption. He's also Chairman of the board at the Spence-Chapin adoption organization, author of the book, Agency, and cofounder of Vertex Partnership Academies, a new network of character-based International Baccalaureate high schools in the Bronx. Along with guest host Eli Lake, the four dads talk: fatherhood, marriage and if it matters anymore, what's up with "toxic masculinity," being a role model for boys, adoption, if the rules and traditions of gender are hurting today's dads or if they offer wisdom we need to re-embrace, and much more. Learn more about your ad choices. Visit megaphone.fm/adchoices
There are nearly 8,000 public charter schools in the United States, serving 3-and-a-half million students. But parents, teachers and thought leaders have a range of views on their role in public education. What are some of the unique challenges administrators face today when establishing and managing a charter school? Do charter schools spark innovation and improvement in the school system at large, or draw resources away from traditional public schools? And how much is the public sentiment regarding charter schools based on the politics of the day? This week, Kevin is joined by Ian Rowe to discuss the purpose and importance of charter schools.
Former President Donald Trump will appear in a Miami federal courtroom tomorrow as he faces 37 counts in a criminal indictment for 'risking national security' by possessing classified documents after leaving office. Many Americans are asking why Trump is facing these potential criminal consequences when similar documents have been found in the possession of President Joe Biden and Hillary Clinton, who were met with different responses from the government. For many Republicans, including New York Congresswoman Nicole Malliotakis, it seems the American justice system's "double standard of justice" could be the culprit behind the Department of Justice's action. On the Rundown, Rep. Malliotakis discusses why she believes government agencies may be "being weaponized against political opponents," and why holding them accountable is crucial. She also discusses House Republicans' plans to continue cutting excess spending in Washington, and why the US should be cautious following news that China is working with Cuba on new spying operations. In 2022, Americans received 225 billion spam calls and texts, up 88 billion from the year prior. As technology advances, scammers are beginning to find more creative ways to gain access to users' crucial personal information. Lately, criminals have been using artificial intelligence to mimic voices to swindle people's family members into giving up credit card information or sometimes even large sums of money. Data security expert and the founder of Dark Box Security Systems, Andrew Sterneke, joins the podcast to discuss the warning signs people should watch out for when receiving suspicious messages, the evolution of scammers' ability to steal sensitive information, and why A.I. technology needs to be watched closely as it is becoming harder to detect fraudsters. Plus, commentary from senior fellow at the American Enterprise Institute, Ian Rowe. Learn more about your ad choices. Visit megaphone.fm/adchoices
In this episode, Dan Proft talks with Ian Row, a senior fellow at the American Enterprise Institute, about the divisive influence of the 1619 Project's curriculum, the alarming trend of self-censorship among students, and the critical role of school choice in providing a balanced education.
0:00 - BLM Brandon is going to keep the silly kids busy this weekend 5:41 - Dan & Charles look over Brandon Johnson's "First We Get the Money" fiscal plan for for our fair city 28:03 - Dan & Charles break down the end of the Tax Credit Scholarship in Illinois 49:57 - Dan & Charles discuss the FBI, IRS and whistleblower Gary Shapley's interview with CBS News 01:04:47 - Host of FOX News' Special Report, Bret Baier, shares updates on the debt ceiling negotiations and the growing GOP field for 2024. Bret is also the #1 Best Selling author of To Rescue the Republic: Ulysses S. Grant, the Fragile Union, and the Crisis of 1876 01:21:18 - Ian Rowe, senior fellow at the American Enterprise Institute & visiting fellow at The Woodson Center, offers a lesson in “Reparations Math” Ian's book Agency: The Four Point Plan (F.R.E.E.) for ALL Children to Overcome the Victimhood Narrative and Discover Their Pathway to Power is now available as a self-narrated audiobook 01:40:28 - Senior Contributor for American Greatness, Julie Kelly, on the latest Jan 6 sentencings and America's progression to Banana Republic. Be sure to check out Julie's most recent book January 6: How Democrats Used the Capitol Protest to Launch a War on Terror Against the Political Right 01:56:26 - OPEN MIC FRIDAY!!See omnystudio.com/listener for privacy information.
Sponsor special: Up to $2,500 of FREE silver AND a FREE safe on qualifying orders - Call 855-862-3377 or text “AMERICAN” to 6-5-5-3-2“If you say that there's structural racism, institutional racism, systemic racism, then I have to insist on one other kind of racism. And that is surmountable racism,” says Ian Rowe, co-founder of Vertex Partnership Academies, a new network of character-focused, International Baccalaureate high schools in the Bronx.Prior to this, he was CEO of the Public Prep charter school network for ten years.“What we owe to young people is to tell them the truth about those behaviors that are far more correlated to success: education, work, faith, family formation, usually marriage before children,” Rowe says.Last year, New York's state and city teachers unions sued to block the creation of his new school system. But less than a week before the school was set to open, Rowe's legal team won a decisive victory.All students at Vertex Partnership Academies take a special course called Pathways to Power.“There are no victims in our school, only architects of their own lives,” Rowe says.Follow American Thought Leaders on social media:Twitter: https://twitter.com/AmThoughtLeaderTruth Social: https://truthsocial.com/@AmThoughtLeaderGettr: https://gettr.com/user/amthoughtleaderFacebook: https://www.facebook.com/AmericanThoughtLeadersGab: https://gab.com/AmThoughtLeaderTelegram: https://t.me/AmThoughtLeader
This is an abbreviated version of The Michael Medved Show. To get the full program, plus premium content, become a subscriber at MichaelMedved.com
Today we take a deep dive on the important education issue of school choice. Megyn Kelly is joined by Ray Domanico of the Manhattan Institute, Corey DeAngelis of the American Federation for Children, Ian Rowe of AEI and author of "Agency," NYC public school parents Mourad Belkas and Chi Lau who are stuck in a failing system, and Arizona parents Kendra and John Scheer who were able to get out of the public system, to talk about declining public school enrollment, the value of having choice, charter schools, the situation in New York City, teachers unions, the decline in school performance because of the COVID pandemic, attacks on merit in America, how vouchers can make an impact, arguments against school choice, the bizarre and unfair NYC public school lottery system, the frustrating choices public school parents are forced to make, the racism of the system toward Asians and immigrants who have focused on integrating into the system, the way the pandemic changed public schools, solutions that empower parents, the "money following the child," the important Arizona bill, charter schools vs. public schools, education freedom and parental rights, and more.Follow The Megyn Kelly Show on all social platforms: YouTube: https://www.youtube.com/MegynKellyTwitter: http://Twitter.com/MegynKellyShowInstagram: http://Instagram.com/MegynKellyShowFacebook: http://Facebook.com/MegynKellyShow Find out more information at: https://www.devilmaycaremedia.com/megynkellyshow
Ian Rowe tells us why America's independence and resilience should give us hope for her future; and Katie Lyon shows us how the American Dream is still alive. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Ian Rowe tells us why America's independence and resilience should give us hope for her future; and Katie Lyon shows us how the American Dream is still alive. Learn more about your ad choices. Visit podcastchoices.com/adchoices