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In today's Research Roundup we bring you four recent studies. How world-class Norwegian endurance coaches programme strength and speed, the factors determining how a runner's physiology holds up over two and a half hours of running, a defence of the critical power model written by the people who built it, and a polarised versus high-intensity trial in cyclists with a result neither of us expected.HIGHLIGHTS AND KEY TOPICS:Strength and speed training across eight Olympic endurance sports (including triathlon, swimming, cycling and running), from 12 world-class Norwegian coaches whose athletes have won over 400 international medals. How many hours a year each sport does, and which sport sits at the bottom of the table.What those sessions look like: exercises, sets, reps and how close to failure the athletes are taken, which is a long way from what randomised trials prescribe. Plus the 10 hours a year of speed training every sport did, and what it looks like.How Daniel and Mikael each place strength and speed work in a real training week, where they differ from the Norwegian model, and why an age-group athlete in their forties is a different case from an Olympic athlete in their twenties.Physiological resilience (durability) during two and a half hours of continuous unfed running, with thresholds, running economy and VO2max retested at the end. Which variables fall most, which barely move, and how runners of different ability differ.Mikael sets the running economy decline against what a pair of carbon shoes buys you and asks which is bigger. Plus the two qualities that separated the runners who held up, one aerobic and one from the gym.Ten common criticisms of the critical power model, answered by the group that built it: whether CP is just FTP renamed, whether the model claims you can hold CP forever, whether a power law fits the curve better, and where the authors concede most.Critical power as a moving number rather than a fixed one, what that does to how you prescribe a threshold session, and the gap between the test durations the paper recommends and the ones Mikael actually uses.Polarised against high intensity with the hard sessions held identical, three a week for six weeks, one group adding four hours a week of easy riding. What the time trial showed, and why Mikael thinks the result is wrong (a strong statement!).SHOWNOTES, LINKS, RESOURCES AND RELATED EPISODES:Follow Daniel Rowland and Endurance Ideas and Implementation on his website, Substack and Instagram.The shownotes for today's episode can be found here.The full podcast episode archives (including category filters) can be found here.Related episodes:New Research on Torque Training, Ketones, Carb Loading and Pacing | Daniel Rowland | EP#698The 10% Rule Applies to Your Long Run, Not Your Week | Research Roundup | EP#709Is VO2max more important than lactate threshold? | Research roundup | EP#705[Triathlon Science] Durability decoded – a 2025 perspective with Michele Zanini, PhDStudies discussed:Strength and Speed Training Practices for Olympic Endurance Sports: Insights From World-Class Coaches - Haugen et al. 2026Determinants of Physiological Resilience Among Recreational-To-Competitive Endurance Runners - Malinen et al. 2026Ten Common Criticisms of the Critical Power Model Revisited - Black et al. 2026The effectiveness of polarized versus high-intensity training in moderately trained cyclists: a randomized parallel-design study - Moran-MacDonald et al. 2026Best-Practice Training Characteristics Within Olympic Endurance Sports as Described by Norwegian World-Class Coaches - Sandbakk et al. 2025Strength Training Improves Running Economy Durability and Fatigued High-Intensity Performance in Well-Trained Male Runners: A Randomized Control Trial - Zanini et al. 2025Effects of Exercise Training on Mitochondrial and Capillary Growth in Human Skeletal Muscle: A Systematic Review and Meta-Regression - Mølmen et al. 2024 SPONSORS: Precision Fuel & Hydration produce our favourite gels, sports drinks, and electrolyte and carbohydrate products here at That Triathlon Show and Scientific Triathlon. Use the free Fuel & Hydration Planner to get a personalised plan for your carbohydrate, sodium and fluid intake in your next event, and get 15% off your first 2026 order by using the code TTS2026 at checkout. Rouvy is hands down the most complete indoor cycling platform for triathletes. Among their thousands of beautiful bike courses from all around the world, all filmed in stunning quality, they have over 75 IRONMAN and IRONMAN 70.3 race courses plus 20+ Challenge Family courses, so you can pre-ride your race from home. Real gradients, real visuals, and real feel! Head to rouvy.com and use the code TTS to get your first month free on top of a 7-day free trial. Effortless Swimming produce the best swim goggles for triathletes and open water swimmers. Their NanoClear anti-fog lenses give you clear, fog-free vision that lasts and doesn't wear off. Don't let foggy or leaky goggles ruin another swim. Go to shop.effortlessswimming.com and use the code TTS15 to get 15% off your goggles, and get a free two-month Effortless Swimming course membership.LEARN MORE ABOUT SCIENTIFIC TRIATHLON: The Scientific Triathlon website is the home of That Triathlon Show and everything else that we doContact us through our contact form or email me directly (note - email/contact form messages get responded to much more quickly than Instagram DMs)Subscribe to our NewsletterFollow us on InstagramLearn more about our coaching, training plans, and training camps. We have something to offer for everybody from beginners to professionals.HOW CAN I SUPPORT THAT TRIATHLON SHOW (FOR FREE)? I really appreciate you reading this and considering helping the show! If you love the show and want to support it to help ensure it sticks around, there are a few very simple things you can do, at no cost other than a minute of your time. Subscribe to the podcast in your podcast app to automatically get all new episodes as they are released.Tell your friends, internet and social media friends, acquaintances and triathlon frenemies about the podcast. Word of mouth is the best way to grow the podcast by far!Rate and review the podcast (ideally five stars of course!) in your podcast app of choice (Spotify and Apple Podcasts are the biggest and most important ones).Share episodes online and on social media. Share your favourite episodes in your Instagram stories, start a discussion about interesting episodes on forums, reference them in your blog or Substack. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
In this episode, Alex Kemper, MD, MPH, MS, FAAP, editor-in-chief of the journal Pediatrics, offers a sampling from the September issue. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with Sonja O'Leary, MD, FAAP, about the role of the school nurse in providing health services. For resources go to aap.org/podcast.
Today on the Yoga Medicine Podcast, Tiffany Cruikshank and co-host Katja Bartsch explore the latest research on strength training during pre- and post-menopause. Using a newly published systematic review and meta-analysis of 126 studies involving more than 4,000 women, they unpack what the evidence actually says about building strength and improving body composition in different stages of reproductive aging. Together, Tiffany and Katja separate common myths from current research, discussing progressive overload, lean muscle, body composition, estrogen, and why strength gains remain possible well into midlife and beyond. They also explore why consistency and enjoyment may be just as important as the specific type of resistance training you choose, offering practical takeaways for yoga practitioners, teachers, and anyone looking to age well. "When we intervene, when we start to create a plan... the capacity to build strength is the same." — Tiffany Cruikshank. — What You'll Learn: Overview of the latest research on strength training across the female lifespan [01:25] Why strength gains remain possible after menopause [08:47] Body composition changes with strength training [16:25] Why enjoyment and consistency are key to long-term success [21:36] Current research gaps and unanswered questions [27:07] Shifting the focus from weight loss to feeling and functioning your best [31:08] How yoga complements strength training for lifelong health [32:34] — Links Mentioned: Watch this episode on YouTube Isenmann E, Geisler S, Havers T, Siegert F, Hemke F, Held S. It's never too late: The impact of resistance training on strength and body composition in females across the lifespan - A systematic review and meta-analysis. J Sci Med Sport. 2026 Mar 18:S1440-2440(26)00096-4. doi: 10.1016/j.jsams.2026.03.002. Epub ahead of print. PMID: 41963141. — Learn More: Find the full show notes at YogaMedicine.com/podcast-173. Learn more about insider tips, online classes or information on our teacher trainings at YogaMedicine.com. To support our work, please leave us a 5 star review with your feedback on iTunes/Apple Podcasts or wherever you listen to podcasts.
Research Round-Up: Sterols and Bile Acids by Journal of Inherited Metabolic Disease
Daniel Rowland and Mikael are back for another research roundup with four recent studies. What blood biomarkers do and do not tell you about training load in elite triathletes, why two athletes with the same VO2max can have very different thresholds, what actually predicts running injuries in a cohort of 5,200 runners, and whether supersets deliver the same strength gains in a third less gym time. HIGHLIGHTS AND KEY TOPICS: VLaMax (maximal glycolytic flux) and metabolic thresholds: the first evidence in real athletes that at a given VO2max, a higher glycolytic rate means a lower threshold power. How VLaMax is measured, why sprint power on its own tells you little to nothing, and whether you can and should measure it and base training decisions off it. How much running is too much: in 5,205 runners tracked over 18 months, a single run 10 to 30% longer than the longest run of the previous 30 days came with a 64% higher injury risk, and bigger jumps than that led to injury risk increasing by well over 100%. Why the acute:chronic workload ratio and the classic weekly 10% rule showed little or no relationship with injury, and why you should never use the performance management chart for controlling running load. Practical long run progression for a marathon or an Ironman, and the one TrainingPeaks chart Mikael looks at more than any other. Four seasons of blood urea and creatine kinase in 20 elite (some world class) triathletes: urea tracks training load, CK does not, and a single reading against a reference range means almost nothing. Why the ratio of objective to subjective training load may be the most useful signal a coach has, and a heuristic for using it in practice. Supersets versus traditional sets: the same strength, hypertrophy, power and body composition gains in 36% less time, 44 minutes per session against 69, and how to apply that to a triathlete's lower body dominant strength programme. SHOWNOTES, LINKS, RESOURCES AND RELATED EPISODES: Follow Daniel Rowland and Endurance: Ideas + Implementation on his website, Substack and Instagram. The shownotes for today's episode can be found here. The full podcast episode archives (including category filters) can be found here. New Research on Torque Training, Ketones, Carb Loading and Pacing | Daniel Rowland | EP#698 Is VO2max more important than lactate threshold? | Research roundup | EP#705 Is Optimised Workout Design Pointless (and Time in Zone What Really Matters)? | Q&A | EP#708 Maximal glycolytic flux modulates metabolic thresholds independent of maximal oxygen uptake - Meixner et al. 2026 How much running is too much? Identifying high-risk running sessions in a 5200-person cohort study - Schuster Brandt Frandsen et al. 2025 Dose-response to endurance training: a longitudinal study of training load and biomarkers in elite triathletes - Cejuela et al. 2026 Less time, same gains: Comparison of superset vs traditional set training on muscular adaptations - Burke et al. 2024 SPONSORS: Precision Fuel & Hydration produce our favourite gels, sports drinks, and electrolyte and carbohydrate products here at That Triathlon Show and Scientific Triathlon. Use the free Fuel & Hydration Planner to get a personalised plan for your carbohydrate, sodium and fluid intake in your next event, and get 15% off your first 2026 order by using the code TTS2026 at checkout. Rouvy is hands down the most complete indoor cycling platform for triathletes. Among their thousands of beautiful bike courses from all around the world, all filmed in stunning quality, they have over 75 IRONMAN and IRONMAN 70.3 race courses plus 20+ Challenge Family courses, so you can pre-ride your race from home. Real gradients, real visuals, and real feel! Head to rouvy.com and use the code TTS to get your first month free on top of a 7-day free trial. Effortless Swimming produce the best swim goggles for triathletes and open water swimmers. Their NanoClear anti-fog lenses give you clear, fog-free vision that lasts and doesn't wear off. Don't let foggy or leaky goggles ruin another swim. Go to shop.effortlessswimming.com and use the code TTS15 to get 15% off your goggles, and get a free two-month Effortless Swimming course membership.LEARN MORE ABOUT SCIENTIFIC TRIATHLON: The Scientific Triathlon website is the home of That Triathlon Show and everything else that we doContact us through our contact form or email me directly (note - email/contact form messages get responded to much more quickly than Instagram DMs)Subscribe to our NewsletterFollow us on InstagramLearn more about our coaching, training plans, and training camps. We have something to offer for everybody from beginners to professionals.HOW CAN I SUPPORT THAT TRIATHLON SHOW (FOR FREE)? I really appreciate you reading this and considering helping the show! If you love the show and want to support it to help ensure it sticks around, there are a few very simple things you can do, at no cost other than a minute of your time. Subscribe to the podcast in your podcast app to automatically get all new episodes as they are released.Tell your friends, internet and social media friends, acquaintances and triathlon frenemies about the podcast. Word of mouth is the best way to grow the podcast by far!Rate and review the podcast (ideally five stars of course!) in your podcast app of choice (Spotify and Apple Podcasts are the biggest and most important ones).Share episodes online and on social media. Share your favourite episodes in your Instagram stories, start a discussion about interesting episodes on forums, reference them in your blog or Substack. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
In this episode, Rachel Moon MD, FAAP, associate editor of blogs for Pediatrics, offers a rundown of the August issue. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with Valencia Walker, MD, FAAP, about social inequities in high-risk neonatal care delivery. For resources go to aap.org/podcast.
In this episode, Andrea Cruz, MD, MPH, FAAP, deputy editor for Pediatrics, offers a rundown of the July issue. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also interview Karen Puopolo, MD, PhD, FAAP, on how to talk about Vitamin K. For resources go to aap.org/podcast.
Phenylketonuria (PKU) was one of the first inherited metabolic disorders to be recognised, but there is still plenty to discover. Silvia Radenkovic and Rodrigo Starosta are joined by Dr Cary Harding and Dr Wendy Smith to discuss evolving treatments, updated management guidelines and where PKU research is heading next. The views and opinions expressed in this podcast are those of the speakers and do not necessarily reflect those of their institutions or organisations.
A research roundup episode, where Dr. Gabriele Gallo (of KnowledgeIsWatt) and myself cover four recent research papers and how they might help us train better and improve our understanding of triathlon and endurance performance HIGHLIGHTS AND KEY TOPICS: Do the same training program twice - get different results? (and how Gabriele and I disagree slightly on the conclusions to draw from this study) Strength training is beneficial for cycling performance, but how beneficial is it really? And is it beneficial for everybody? Finally, how should you structure your strength training program to make it so? A massive review on the impact of different types of endurance training on mitochondrial and capillary growth, and VO2max improvements. What separates athletes of different performance levels is not how high they can push their threshold as a percentage of VO2max, but how high the VO2max is in the first place. SHOWNOTES, LINKS, RESOURCES AND RELATED EPISODES: Follow Gabriele and KnowledgeIsWatt on his website, Substack and Instagram The shownotes for today's episode can be found here. The full podcast episode archives (including category filters) can be found here. Limited reproducibility of individual physiological adaptations to repeated endurance exercise training - Odden et al. 2026 Heavy strength training effects on physiological determinants of endurance cyclist performance: a systematic review with meta-analysis - Llanos-Lagos et al. 2025 Effects of Exercise Training on Mitochondrial and Capillary Growth in Human Skeletal Muscle: A Systematic Review and Meta-Regression - Mølmen et al. 2024 Elite Aerobic Endurance Performance: Is It Really Related to Lactate Threshold Expressed Relative to Peak Oxygen Uptake? - Johansen et al. 2025 Strength training improves performance and pedaling characteristics in elite cyclists - Rønnestad et al. 2014 Five-Minute Power-Based Test to Predict Maximal Oxygen Consumption in Road Cycling - Sitko et al. 2022 SPONSORS: Precision Fuel & Hydration produce our favourite gels, sports drinks, and electrolyte and carbohydrate products here at That Triathlon Show and Scientific Triathlon. Use the free Fuel & Hydration Planner to get a personalised plan for your carbohydrate, sodium and fluid intake in your next event, and get 15% off your first 2026 order by using the code TTS2026 at checkout. Rouvy is hands down the most complete indoor cycling platform for triathletes. Among their thousands of beautiful bike courses from all around the world, all filmed in stunning quality, they have over 75 IRONMAN and IRONMAN 70.3 race courses plus 20+ Challenge Family courses, so you can pre-ride your race from home. Real gradients, real visuals, and real feel! Head to rouvy.com and use the code TTS to get your first month free on top of a 7-day free trial. Effortless Swimming produce the best swim goggles for triathletes and open water swimmers. Their NanoClear anti-fog lenses give you clear, fog-free vision that lasts and doesn't wear off. Don't let foggy or leaky goggles ruin another swim. Go to shop.effortlessswimming.com and use the code TTS15 to get 15% off your goggles, and get a free two-month Effortless Swimming course membership. ZenAI is the next frontier of podcasting. It lets you turn your ideas into a podcast without any knowledge of audio editing, video, or production. You do the talking, and the AI handles the production, editing, clipping, and the rest, and you can direct your AI producer in plain English. You can even record from your phone, so no expensive studio gear is needed to sound great. ZenAI is a new product from Zencastr, a platform I've been a paying customer of for over nine years here at That Triathlon Show. ZenAI is currently in invite-only beta. Join the waitlist today here.LEARN MORE ABOUT SCIENTIFIC TRIATHLON: The Scientific Triathlon website is the home of That Triathlon Show and everything else that we doContact us through our contact form or email me directly (note - email/contact form messages get responded to much more quickly than Instagram DMs)Subscribe to our NewsletterFollow us on InstagramLearn more about our coaching, training plans, and training camps. We have something to offer for everybody from beginners to professionals.HOW CAN I SUPPORT THAT TRIATHLON SHOW (FOR FREE)? I really appreciate you reading this and considering helping the show! If you love the show and want to support it to help ensure it sticks around, there are a few very simple things you can do, at no cost other than a minute of your time. Subscribe to the podcast in your podcast app to automatically get all new episodes as they are released.Tell your friends, internet and social media friends, acquaintances and triathlon frenemies about the podcast. Word of mouth is the best way to grow the podcast by far!Rate and review the podcast (ideally five stars of course!) in your podcast app of choice (Spotify and Apple Podcasts are the biggest and most important ones).Share episodes online and on social media. Share your favourite episodes in your Instagram stories, start a discussion about interesting episodes on forums, reference them in your blog or Substack. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Back from the ADSA annual meeting in Milwaukee, Brad shares highlights from several calf-focused dairy studies. This episode covers new research on colostrum management for beef-on-dairy crossbred calves, including how feeding practices differ between retained dairy heifers, beef-on-dairy calves, and calves not kept on farm.Brad also reviews a study comparing fixed-age weaning with starter-intake-based weaning in Holstein and Angus-Holstein calves, plus new work using ear tag sensors to track calf behavior, rumination, eating, and activity through 150 days of age. The episode wraps up with research from the University of Florida on colostrum yield, quality, and genetics, including how season, parity, calf sex, gestation length, and days dry can influence colostrum outcomes.Questions, comments, scathing rebuttals? -> themoosroom@umn.edu or call 612-624-3610 and leave us a message!Linkedin -> The Moos RoomTwitter -> @UMNmoosroom and @UMNFarmSafetyFacebook -> @UMNDairyYouTube -> UMN Beef and Dairy and UMN Farm Safety and HealthInstagram -> @UMNWCROCDairyExtension WebsiteAgriAmerica Podcast Directory
In this Research Roundup episode of the Fiercely Fueled Nutrition Podcast, we dive into the long-standing gaps in women's sports science and why female athletes have been consistently underserved in research, coaching, and performance conversations. From hormone fluctuations and menstrual cycle myths to underrepresentation in clinical studies, this episode unpacks how outdated research models have shaped the way women are trained, fueled, and supported in sport. We explore the real-world impact this has on performance, recovery, injury risk, and long-term health, while highlighting the growing movement toward better science and more individualized approaches for female athletes. If you've ever felt like training advice wasn't built with women in mind, this conversation is for you. Episode Highlights: ✅ Why women have historically been excluded from sports research ✅ How hormonal cycles impact training, recovery, and performance ✅ Common myths about female athletes and strength training ✅ The consequences of using male-based research for women's programs ✅ Injury risk, recovery, and fueling differences in women ✅ Why individualized coaching matters for female athletes ✅ The future of women-focused sports science and performance research APPLY FOR COACHING https://10tkto34p7j.typeform.com/to/aI4uHZgU Get our free pre & post-training meals guide https://guide.fiercelyfueled.com/podcast Follow Fiercely Fueled Nutrition: Instagram: @fiercelyfuelednutrition https://www.instagram.com/fiercelyfuelednutrition/
In this episode, Alex Kemper, MD, MPH, MS, FAAP, editor-in-chief of the journal Pediatrics, offers a sampling from the June issue. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with Robert Murray, MD, FAAP about the crucial role of recess in school. For resources go to aap.org/podcast.
Season 2 of the JIMD Research Round-Up begins with a deep dive into classical homocystinuria (CBS deficiency). Hosts Silvia Radenkovic and Rodrigo Starosta are joined by two internationally recognised experts, Dr Andrew Morris (Royal Manchester Children's Hospital, UK) and Professor Kim Chapman (Children's Hospital Los Angeles, USA). In this episode, they explore: - The clinical spectrum of homocystinuria, from childhood presentations to adults diagnosed after thrombosis - Why the condition is still frequently missed or misdiagnosed - The overlap with Marfan syndrome and the unanswered questions surrounding disease mechanisms - The strengths and limitations of current newborn screening programmes - Dietary treatment, pyridoxine responsiveness, and the challenges faced by patients and families - Emerging therapies including enzyme substitution therapy, chaperone therapies, and ongoing clinical trials - Why there is genuine optimism for the future of homocystinuria care and research A fascinating discussion covering six decades of progress in homocystinuria and the next generation of treatments that may transform care.
In this episode, Yoga Medicine founder Tiffany Cruikshank and Katja Bartsch take a deep dive into the latest stretching research and what it means for yoga teachers, athletes, and movement professionals. Together, they unpack the latest recommendations around stretching for flexibility, stiffness, strength, hypertrophy, vascular health, recovery, and injury prevention while exploring the limitations of stretching as a standalone tool. Tiffany and Katja discuss why prolonged static stretching before explosive activity may impair athletic performance, how longer-held yin-style stretches may influence tissue stiffness, and why emerging vascular research around stretching is generating so much interest. They also explore why yoga recovery likely involves far more than just stretching mechanics, including nervous system regulation, breathwork, and relaxation. "We do not overestimate or underestimate what stretching can do." — Katja Bartsch. — What You'll Learn: What the new 2025 stretching consensus paper reveals about flexibility research [02:57] • Definitions of static, dynamic, and PNF stretching in both research and yoga practice [06:00] • Acute vs. chronic stretching effects on range of motion and mobility [13:54] • Recommendations for improving long-term flexibility and maintaining mobility with age [20:09] • The "Goldilocks" principle of tissue stiffness and athletic performance [27:24] • Why longer yin-style holds may influence connective tissue adaptation [32:12] • How stretching impacts strength, explosive performance, and warm-ups [34:32] • Research on stretching for strength gains and muscle hypertrophy [37:36] • Emerging evidence around stretching and vascular health [42:01] • Breathwork, nervous system regulation, and yoga's broader therapeutic effects [51:24] • Why stretching alone may not improve recovery or prevent soreness [54:07] • The limitations of flexibility-only approaches for injury prevention [1:00:13] • Why individualized mobility, stability, and strength work matter in yoga practice [1:01:40] • Final takeaways on stretching frequency, recovery, and long-term mobility [1:04:32] — Links Mentioned: Watch this episode on YouTube Warneke K, Thomas E, Blazevich AJ, Afonso J, Behm DG, Marchetti PH, Trajano GS, Nakamura M, Ayala F, Longo S, Babault N, Freitas SR, Costa PB, Konrad A, Nordez A, Nelson A, Zech A, Kay AD, Donti O, Wilke J. Practical recommendations on stretching exercise: A Delphi consensus statement of international research experts. J Sport Health Sci. 2025 Dec;14:101067. doi: 10.1016/j.jshs.2025.101067. Epub 2025 Jun 11. PMID: 40513717; PMCID: PMC12305623. — Learn More: Find the full show notes at YogaMedicine.com/podcast-167. Learn more about insider tips, online classes or information on our teacher trainings at YogaMedicine.com. To support our work, please leave us a 5 star review with your feedback on iTunes/Apple Podcasts or wherever you listen to podcasts.
In this episode, Rachel Moon MD, FAAP, associate editor of blogs for Pediatrics, offers a rundown of the May issue. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with Evelyn Berger-Jenkins, MD, MPH, FAAP, about a framework for approaching healthy mental and emotional development in pediatrics. For resources go to aap.org/podcast.
In this episode, Andrea Cruz, MD, MPH, FAAP, deputy editor for Pediatrics, offers a rundown of the April issue. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with Hans Kersten, MD, FAAP, about the diagnosis and management of faltering weight. For resources go to aap.org/podcast.
In this episode, Alex Kemper, MD, MPH, MS, FAAP, editor-in-chief of the journal Pediatrics, offers a sampling from the March issue. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with Allison Empey, MD, FAAP, about considerations in research with American Indian and Alaska Native communities. For resources go to aap.org/podcast.
In this episode, Patrick Brady, MD, MSc, FAAP, editor-in-chief for Hospital Pediatrics, offers a rundown of the February issue. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with Justin Long, MD, FAAP, about critical elements for the pediatric periprocedural anesthesia environment. For resources go to aap.org/podcast.
This episode is a research round up! We are discussing three new (ish) studies and reviews on nutrition, strength training, and a study that helped us change our mind! Nutrition: The effect of fasting or calorie restriction on autophagy induction: A review of the literature Strength Training: Muscular Adaptations in Single-Set Resistance Training Performed to Failure or with Repetitions-in-Reserve Changed our Minds: The Sweet Tooth Trial
In this episode, Rachel Moon, MD, FAAP, associate editor of blogs for Pediatrics, offers a rundown of the February issue. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with Steven Bondi, MD, JD, FAAP, about providing medical care for parents during the pediatric visit. For resources go to aap.org/podcast.
In this episode, Andrea Cruz, MD, MPH, FAAP, deputy editor for Pediatrics, offers a rundown of the January issue. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with Meg Parker, MD, MPH, FAAP, about promoting human milk and breastfeeding for the very low birth weight infant. For resources go to aap.org/podcast.
In this episode I sit down with my friend and Vulnerability Researcher Patrick Garrity
In this episode, Alex Kemper, MD, MPH, MS, FAAP, editor-in-chief of the journal Pediatrics, offers a sampling from the December issue. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with Sean O'Leary, MD, MPH, FAAP, about effective strategies for communicating with families about vaccines. For resources go to aap.org/podcast.
The Research Round-Up returns! Hosts Silvia Radenkovic and Rodrigo Starosta are joined by Dr Hilary Vernon and Dr Austin Larson for a deep dive into the latest discoveries in mitochondrial disease. Together they explore how new biomarkers like FGF21 and GDF15 are reshaping diagnosis, how multi-omics approaches are accelerating precision care, and what large-scale data from gnomAD to stem-cell models is revealing about disease mechanisms and therapeutic opportunities. A lively, expert-led discussion connecting science, diagnostics, and patient impact across the mitochondrial field. Laricchia KM, et al Mitochondrial DNA variation across 56,434 individuals in gnomAD. Genome Res. 2022 Mar;32(3):569-582. doi: 10.1101/gr.276013.121. Epub 2022 Jan 24. PMID: 35074858; PMCID: PMC8896463. Liu O, et al FGF21 and GDF15 are elevated in Barth Syndrome and are correlated to important clinical measures. Mol Genet Metab. 2023 Nov;140(3):107676. doi: 10.1016/j.ymgme.2023.107676. Epub 2023 Aug 2. PMID: 37549445. Van Hove JLK, et al Protein biomarkers GDF15 and FGF21 to differentiate mitochondrial hepatopathies from other pediatric liver diseases. Hepatol Commun. 2024 Jan 5;8(1):e0361. doi: 10.1097/HC9.0000000000000361. Erratum in: Hepatol Commun. 2024 Jan 29;8(2):e0390. doi: 10.1097/HC9.0000000000000390. PMID: 38180987; PMCID: PMC10781130. Starosta RT, et al An integrated multi-omics approach allowed ultra-rapid diagnosis of a deep intronic pathogenic variant in PDHX and precision treatment in a neonate critically ill with lactic acidosis. Mitochondrion. 2024 Nov;79:101973. doi: 10.1016/j.mito.2024.101973. Epub 2024 Oct 15. PMID: 39413893; PMCID: PMC11578067. Jain IH, et al Hypoxia as a therapy for mitochondrial disease. Science. 2016 Apr 1;352(6281):54-61. doi: 10.1126/science.aad9642. Epub 2016 Feb 25. PMID: 26917594; PMCID: PMC4860742 Sandlers Y, et al Metabolomics Reveals New Mechanisms for Pathogenesis in Barth Syndrome and Introduces Novel Roles for Cardiolipin in Cellular Function. PLoS One. 2016 Mar 25;11(3):e0151802. doi: 10.1371/journal.pone.0151802. PMID: 27015085; PMCID: PMC4807847. Sniezek Carney O, et al. Stem cell models of TAFAZZIN deficiency reveal novel tissue-specific pathologies in Barth syndrome. Hum Mol Genet. 2025 Jan 23;34(1):101-115. doi: 10.1093/hmg/ddae152. PMID: 39535077; PMCID: PMC11756277.
In this episode Rachel Moon, MD, FAAP, associate editor of blogs for Pediatrics, offers a rundown of the November issue. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with Andrea Hadley, MD, FAAP, about the role of medical psychiatric units in supporting pediatric mental health. For resources go to aap.org/podcast.
Wharton's Philip Nichols explains why AI isn't useful for combatting corruption, at least not yet. This Ripple Effect episode is part of the “Research Roundup” series. Hosted on Acast. See acast.com/privacy for more information.
With Rodrigo off caring for sick children, James Nurse joins Silvia Radenkovic to speak with Dr Judith Jans and Dr Devin Oglesbee about the emerging field of untargeted metabolomics. Authors' opinions are their own and do not represent their institutions. Referenced papers include: Miller MJ, et al The emerging role of metabolomics analysis in genetic and genomic testing: A points to consider statement of the American College of Medical Genetics and Genomics (ACMG). Genet Med. 2025 Jul 17:101493. doi: 10.1016/j.gim.2025.101493. Epub ahead of print. Evans AM, et al Dissemination and analysis of the quality assurance (QA) and quality control (QC) practices of LC-MS based untargeted metabolomics practitioners. Metabolomics. 2020 Oct 12;16(10):113. doi: 10.1007/s11306-020-01728-5. Wurth R, et al. An evaluation of untargeted metabolomics methods to characterize inborn errors of metabolism. Mol Genet Metab. 2024 Jan;141(1):108115. doi: 10.1016/j.ymgme.2023.108115. Epub 2023 Dec 15. Haijes HA, et al. Direct Infusion Based Metabolomics Identifies Metabolic Disease in Patients' Dried Blood Spots and Plasma. Metabolites. 2019 Jan 11;9(1):12. doi: 10.3390/metabo9010012. Willems AP, et al A one-year pilot study comparing direct-infusion high resolution mass spectrometry based untargeted metabolomics to targeted diagnostic screening for inherited metabolic diseases. Front Mol Biosci. 2023 Nov 2;10:1283083. doi: 10.3389/fmolb.2023.1283083. Haijes HA, et al. Aspartylglycosamine is a biomarker for NGLY1-CDDG, a congenital disorder of deglycosylation. Mol Genet Metab. 2019 Aug;127(4):368-372. doi: 10.1016/j.ymgme.2019.07.001. Epub 2019 Jul 9. PMID: 31311714. Hoegen B, et al Application of metabolite set enrichment analysis on untargeted metabolomics data prioritises relevant pathways and detects novel biomarkers for inherited metabolic disorders. J Inherit Metab Dis. 2022 Jul;45(4):682-695. doi: 10.1002/jimd.12522. Epub 2022 May 22. PMID: 35546254; PMCID: PMC9544878. Gao Q, et al A diagnostic algorithm for inherited metabolic disorders using untargeted metabolomics. Metabolomics. 2025 Jul 27;21(4):101. doi: 10.1007/s11306-025-02302-7. PMID: 40715884; PMCID: PMC12301266. Kerkhofs MHPM, et al. Cross-Omics: Integrating Genomics with Metabolomics in Clinical Diagnostics. Metabolites. 2020 May 18;10(5):206. doi: 10.3390/metabo10050206. Ashenden AJ, et al. The Multi-Omic Approach to Newborn Screening: Opportunities and Challenges. Int J Neonatal Screen. 2024 Jun 21;10(3):42. doi: 10.3390/ijns10030042. Liu N, et al. Comparison of Untargeted Metabolomic Profiling vs Traditional Metabolic Screening to Identify Inborn Errors of Metabolism. JAMA Netw Open. 2021 Jul 1;4(7):e2114155. doi: 10.1001/jamanetworkopen.2021.14155.
Silvia and Rodrigo are joined by Dr Ray Wang, Director of the multidisciplinary Foundation of Caring Lysosomal Storage Disorder Program at the Children's Hospital of Orange County. Silvia asks Dr Wang and Rodrigo (who also happens to be a researcher in this field) about cutting-edge advances in LSD research: from base editing in Pompe disease and patient-specific in vivo gene editing, to new biomarkers and scoring systems in Gaucher disease, insights into lipid dysregulation across lysosomal storage disorders, and the first clinical trial of anakinra in Sanfilippo syndrome. Papers discussed include: Christensen CL, et al Base editing rescues acid α-glucosidase function in infantile-onset Pompe disease patient-derived cells. Mol Ther Nucleic Acids. 2024 May 21;35(2):102220. doi: 10.1016/j.omtn.2024.102220. PMID: 38948331; PMCID: PMC11214518. Starosta RT, et al Predicting liver fibrosis in Gaucher disease: Investigation of contributors and development of a clinically applicable Gaucher liver fibrosis score. Mol Genet Metab. 2025 Feb;144(2):109010. doi: 10.1016/j.ymgme.2025.109010. Epub 2025 Jan 3. PMID: 39788861. Kell P, et al Secondary accumulation of lyso-platelet activating factors in lysosomal storage diseases. Mol Genet Metab. 2025 Jun 17;145(4):109180. doi: 10.1016/j.ymgme.2025.109180. Polgreen LE, et al Anakinra in Sanfilippo syndrome: a phase 1/2 trial. Nat Med. 2024 Sep;30(9):2473-2479. doi: 10.1038/s41591-024-03079-3. Epub 2024 Jun 21. Erratum in: Nat Med. 2024 Sep;30(9):2693. doi: 10.1038/s41591-024-03207-z. Musunuru K, et al Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease. N Engl J Med. 2025 Jun 12;392(22):2235-2243. doi: 10.1056/NEJMoa2504747.
What's the latest thinking in managing patellofemoral pain? Drs Erin Macri (Erasmus MC University Medical Centre, The Netherlands) and Harvi Hart (Michigan State University) join JOSPT Insights ahead of the International Patellofemoral Research Network meeting to share the latest in patellofemoral research, and what it means for clinical practice. ------------------------------ RESOURCES JOSPT Insights Ep 229: Best practice in managing patellofemoral pain, with Dr Brad Neal: https://pod.link/1522929437/episode/ZDBkY2Q0ZDYtMzNhZS00OWVjLWJlYTQtNTYwMzBkZTVhM2Iw Patellofemoral pain CPG: https://www.jospt.org/doi/10.2519/jospt.2019.0302 Clinical priorities for psychological factors in patellofemoral pain: https://www.jospt.org/doi/10.2519/jospt.2022.10647 Prognosis for patellofemoral pain: https://www.jospt.org/doi/10.2519/jospt.2025.13491 Find out more about the International Patellofemoral Research Network's work: https://ipfrn.org/
In this episode the new deputy editor of Pediatrics joins the team.Andrea Cruz, MD, MPH, FAAP, offers a rundown of the September issue of the journal. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with Tim Geleske, MD, FAAP, about genetic evaluation of children with intellectual disabilities or global developmental delays. For resources go to aap.org/podcast.
Today, hosts Tiffany and Katja discuss current research on female hormones, the immune system, and exercise. Both the female hormones as well as the immune function are intricate systems – bringing them together adds even more complexity! In this episode, we try to boil down the immune system and inflammatory response and explore recent research that sheds light on the relationship between the menstrual cycle, immune responses and exercise. We also discuss the nuances of inflammatory processes, individualised responses, and potential implications for peri- and post-menopause. Listen in as we talk about the influence of female hormones on immune processes and share why inner wisdom is an important part of understanding our bodies better. — Show Notes: Disclaimer – complexity of the immune system and menstrual cycle research [1:52] Inflammation and the immune system – bird's eye view [4:18] Influence of female hormones on immune and inflammatory processes [6:47] Potential changes in the second phase of the menstrual cycle [14:16] Current meta-analysis and systematic review on female hormones and immune function/ inflammation [15:43] Relationship with exercise [22:41] Current state of menstrual cycle-based training research [29:33] — Links Mentioned: Watch this episode on YouTube Female Hormones & Immune System References Doc Female Health Yoga Teacher Training Menopause Yoga Teacher Training Connect with Katja Bartsch: Facebook | Instagram | Kalamana Yoga | Yoga Medicine® Online Guest Teacher You can learn more about this episode, and see the full show notes at YogaMedicine.com/podcast-142. And you can find out more about insider tips, online classes or information on our teacher trainings at YogaMedicine.com. To support our work, please leave us a 5 star review with your feedback on iTunes/Apple Podcasts.
In this episode, Prof Chris Vorster (Director, Centre for Human Metabolomics, North-West University, South Africa), Sarah Viall (Assistant Professor, Molecular and Medical Genetics, Oregon Health & Science University, USA) and PD Dr. med. Ulrike Mütze (Consultant, Heidelberg University Hospital, Germany) join Silvia Radenkovic and Rodrigo Starosta to explore the evolving landscape of newborn screening. They discuss national and international variations in practice, how to maintain consistency and quality, and the future scope of testing – including opportunities to improve access in resource-limited settings. Authors' opinions are their own and do not represent their institutions. Referenced papers include: Newborn screening in South Africa: the past, present, and plans for the future. Malherbe et al (2024) Clinical validation of cutoff target ranges in newborn screening of metabolic disorders by tandem mass spectrometry: a worldwide collaborative project. McHugh et al (2024) Five years of newborn screening for Pompe, Mucopolysaccharidosis type I, Gaucher, and Fabry diseases in Oregon. Viall & Held (2025) Long-term outcomes of adolescents and young adults identified by metabolic newborn screening. Mütze et al (2025) Treatment Outcomes for Maple Syrup Urine Disease Detected by Newborn Screening. Mengler et al (2024) Vitamin B12 Deficiency Newborn Screening. Mütze et al (2024) The role of exome sequencing in newborn screening for inborn errors of metabolism. Adhikari et al (2020)
In this episode, Alex Kemper, MD, MPH, MS, FAAP, editor of the journal Pediatrics, offers a rundown of the August issue. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with Jesse Hackell, MD, FAAP, about medical versus non-medical immunization exemptions for child care and school attendance. For resources go to aap.org/podcast.
In this episode, Dr Joost Groen, a clinical biochemist at the University Medical Center Groningen, and Dr Matt Gentry, Professor & Chair of Biochemistry & Molecular Biology in the College of Medicine at University of Florida, join Rodrigo and Silvia to discuss new insights, AI, cancer metabolism and some of their favourite papers on Glycogen Storage Disorders. Authors opinions are their own and do not represent their institutions. GSD episode papers: Brain glycogen serves as a critical glucosamine cache required for protein glycosylation. Sun et al A machine learning model accurately identifies glycogen storage disease Ia patients based on plasma acylcarnitine profiles. Groen et al Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders. Ullman et al Repurposing SGLT2 inhibitors: Treatment of renal proximal tubulopathy in Fanconi-Bickel syndrome with empagliflozin. Overduin et al Gross-Valle The relation between dietary polysaccharide intake and urinary excretion of tetraglucoside. Gross-Valle et al Glycogen drives tumour initiation and progression in lung adenocarcinoma. Clarke HA et al Spatial metabolomics reveals glycogen as an actionable target for pulmonary fibrosis. Conroy et al In situ mass spectrometry imaging reveals heterogeneous glycogen stores in human normal and cancerous tissues. Young et al Glycogen accumulation modulates life span in a mouse model of amyotrophic lateral sclerosis. Brewer et al Dynamics of cognitive variability with age and its genetic underpinning in NIHR BioResource Genes and Cognition cohort participants. Rahman MS et al Neurological glycogen storage diseases and emerging therapeutics Colpaert et al
There are still plenty of questions about the experience of the transitional phases of our lives. Today, hosts Tiffany and Katja discuss recent research that seeks to shed light on the menopausal transition. Experience of menopause is highly variable from person to person, so in this episode, we explore common symptom clusters identified in the research as well as the phenomenon of “not feeling like myself” in perimenopause. We also talk about how midlife can pose a challenge to one's self-image and discuss how fatigue and emotional volatility may impact a woman's day-to-day in this phase of life. — Show Notes: Background on menopause and perimenopause [2:50] Symptoms of peri- and postmenopause [14:41] Symptoms that show up in all stages of menopause [27:19] The phenomenon of “not feeling like myself” in perimenopause [29:22] Symptoms related to not feeling like yourself [38:20] The role of fatigue [45:17] New sensations of emotional volatility [46:38] — Links Mentioned: Watch this episode on YouTube Menopause References Doc Connect with Katja Bartsch: Facebook | Instagram | Kalamana Yoga | Yoga Medicine® Online Guest Teacher You can learn more about this episode, and see the full show notes at YogaMedicine.com/podcast-139. And you can find out more about insider tips, online classes or information on our teacher trainings at YogaMedicine.com. To support our work, please leave us a 5 star review with your feedback on iTunes/Apple Podcasts.
In this episode Rachel Moon, MD, FAAP, associate editor of digital media for Pediatrics, offers a rundown of the July issue. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with Dana Kaplan, MD, FAAP, about human trafficking and exploitation of children and adolescents. For resources go to aap.org/podcast.
Send us a textIn this edition of our occasional recent research review, we focus on scientific evidence for dyslexic strengths.The articles we reference are:Lukic, S., Jiang, F., Mandelli, M. L., Qi, T., Inkelis, S. M., Rosenthal, E., Miller, Z., Wellman, E., Bunge, S. A., Gorno‑Tempini, M. L., & Pereira, C. W. (2025).A semantic strength and neural correlates in developmental dyslexia. Frontiers in Psychology, 15, Article 1405425. https://doi.org/10.3389/fpsyg.2024.1405425 Maw, K. J., Beattie, G., & Burns, E. J. (2024).Cognitive strengths in neurodevelopmental disorders, conditions and differences: A critical review. Neuropsychologia, 197, Article 108850. https://doi.org/10.1016/j.neuropsychologia.2024.108850Dyslexia Journey has conversations and explorations to help you support the dyslexic child in your life. Content includes approaches, tips, and interviews with a range of guests from psychologists to educators to people with dyslexia. Increase your understanding and connection with your child as you help them embrace their uniqueness and thrive on this challenging journey!Send us your questions, comments, and guest suggestions to parentingdyslexiajourney@gmail.comAlso check out our YouTube channel! https://www.youtube.com/@ParentingDyslexiaJourney
Dr Luciana Hannibal, Research Group Leader / Head of Translational Metabolomics at the Centre for Integrative Biological Signalling Studies in Freiburg, and Dr Julien Park, a Physician-scientist at the Children's University Hospital Münster, are Rodrigo and Silvia's latest guests, providing a thorough overview of disorders of Redox Metabolism. Authors opinions are their own and do not represent their institutions. Papers discussed include: Targeted Metabolic Profiling of Methionine Cycle Metabolites and Redox Thiol Pools in Mammalian Plasma, Cells and Urine Behringer et al Treatment with 2-phospho-L-ascorbic acid mitigates biochemical phenotypes of heme oxygenase 1 deficiency Berendes et al Guidelines for measuring reactive oxygen species and oxidative damage in cells and in vivo Murphy et al The motor system is exceptionally vulnerable to absence of the ubiquitously expressed superoxide dismutase-1 Park et al Clinical and molecular analysis of a novel variant in heme oxygenase-1 deficiency: Unraveling its role in inflammation, heme metabolism, and pulmonary phenotype Berendes et al Redox signaling in inherited diseases of metabolism, Current Opinion in Physiology Jacobsen and Hannbal Real-time detection of enzymatically formed hydrogen sulfide by pathogenic variants of cystathionine beta-synthase using hemoglobin I of Lucina pectinata as a biosensor. Myszkowska et al
In this episode Lewis First, MD, MS, FAAP, editor-in-chief of Pediatrics, is back for a special edition of “First Up.” He offers an overview of the June issue of the journal. Hosts David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also welcome a couple of surprise guests who share their favorite Lewis memories. For resources go to aap.org/podcast.
Dr Sabine Fuchs, Professor of Metabolic diseases and innovative therapies at the UMC Utrecht, and Dr Sean Froese, a Principal Investigator in the Metabolism Division at University Children's Hospital Zürich, join Rodrigo and Silvia to discuss new insights and some of their favourite papers on Methylmalonic Aciduria. Authors opinions are their own and do not represent their institutions. Papers discussed include: Integrated multi-omics reveals anaplerotic rewiring in methylmalonyl-CoA mutase deficiency Forny et al Aberrant methylmalonylation underlies methylmalonic acidemia and is attenuated by an engineered sirtuin. Head et al Lipodystrophy in methylmalonic acidemia associated with elevated FGF21 and abnormal methylmalonylation. Manoli et al Prime editing for functional repair in patient-derived disease models Schene et al Mutation-specific reporter for optimization and enrichment of prime editing Schene et al Biomarkers to predict disease progression and therapeutic response in isolated methylmalonic acidemia. Manoli et al Fibroblast growth factor 21 as a biomarker for long-term complications in organic acidemias. Molema et al
As both yoga teachers and practitioners, it is important to understand how to take general instruction and use it to cater to your personal needs. In this episode, hosts Tiffany and Katja talk about recent research on personalized medicine and training, discuss how wearables and data collection play into individualized training programs, and relate current research findings to personalized yoga approaches. Listen to this episode to learn about the history and trends of individualised medicine and training, how to know which data to collect, why body awareness is important in individualisation, and how to take this perspective into account in a group class. — Show Notes: What is the history of personalized medicine, training, and yoga [2:04] Factors to consider [8:31] Tracking and evaluating data [12:12] Current research and potential downsides [20:37] How to individualize a group class [35:32] Recap [37:49] — Links Mentioned: Watch this episode on YouTube Connect with Katja Bartsch: Facebook | Instagram | Kalamana Yoga | Yoga Medicine® Online Guest Teacher You can learn more about this episode and see the full show notes at YogaMedicine.com/podcast-135. And you can find out more about insider tips, online classes or information on our teacher trainings at YogaMedicine.com. To support our work, please leave us a 5 star review with your feedback on iTunes/Apple Podcasts.
In this episode Alex R. Kemper, MD, MPH, MS, FAAP, deputy editor of the journal Pediatrics, offers a rundown of the May issue. Hosts David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also talk to Ellen S. Rome, MD, MPH, FAAP, about the latest updates in the ninth edition of the Yellow Book, Pediatric Nutrition. For resources go to aap.org/podcast.
In this episode Rachel Moon, MD, FAAP, associate editor of digital media for the journal Pediatrics, shares a research roundup from the April issue. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with Adam Ratner, MD, MPH, FAAP, and Nitya Shah, MD, FAAP, about having difficult conversations with families about a diagnosis of congenital syphilis and other diseases. For resources go to aap.org/podcast.
Send us a textThe quest for better outcomes in pediatric IBD has taken significant strides forward, and Dr. Jeremy Adler returns to Bowel Moments to guide us through the most promising research developments of the past year. Dr. Adler is a clinical Professor in the Division of Pediatric Gastroenterology at the University of Michigan and serves as the Interim Director of the Susan B. Meister Child Health Evaluation and Research (CHEAR) Center. We discuss how medication dosing strategies have evolved dramatically, with compelling evidence showing that body surface area measurements work better than traditional weight-based dosing for younger children. This seemingly simple adjustment yields dramatically better results, particularly as children grow and develop through puberty. Regular therapeutic drug monitoring—checking medication levels every 6-12 months or more frequently during growth spurts—has also proven critical for maintaining disease control in the pediatric population.Prevention emerges as the cornerstone of Dr. Adler's research and clinical philosophy. The fascinating GEM study has identified changes in gut permeability that occur before IBD diagnosis, potentially opening doors to early intervention before symptoms appear. Meanwhile, Dr. Adler's own groundbreaking research demonstrates that early, aggressive treatment with anti-TNF medications can prevent serious complications like perianal fistulas, fistulas, and abscesses—complications that significantly impact quality of life and body image.We navigate the complex terrain of treatment barriers, from insurance denials to psychological resistance to "stronger" medications. Dr. Adler challenges common misconceptions, noting that injectable or infusion medications often have better safety profiles than some oral options that patients perceive as "less intense." The conversation turns to normalizing surgical options like ostomies when needed, with Dr. Adler advocating for early introduction to surgical teams—not because surgery is imminent, but because establishing relationships reduces trauma if intervention becomes necessary.With new medication mechanisms emerging and genetic markers helping to personalize treatment approaches, the research landscape offers real hope for children with IBD. Join us for this candid, informative discussion about protecting children from the worst outcomes of IBD through early intervention, personalized treatment, and collaborative care models that address both physical and mental wellbeing.Links: Research article- Preventing Fistulas and Strictures Among Children with Crohn's DiseaseJournal Article referenced- National Perspectives of Barriers by Insurance and Pharmacy Benefits Managers in Pediatric Inflammatory Bowel DiseaseImproveCareNowLet's get social!!Follow us on Instagram!Follow us on Facebook!Follow us on Twitter!
In this episode, Meredith and Alex dive into a research roundup on essential health topics, including sleep, exercise, diet, and alcohol. They explore the benefits and trade-offs of morning vs. evening exercise, the importance of eating breakfast, the numerous wellness advantages of spending time outdoors, and the impact of community and social connections on overall well-being. Additionally, they discuss alcohol consumption and its effects on diet, sleep, and exercise habits, plus an interesting study on whether alcohol consumers actually exercise more.— The Podcast Couch Dilemma— Life Updates & Meredith's Frostbite— Morning vs. Evening Workouts— The Science Behind the Benefits of Getting Outside— Community and Social Connection— The Importance of Quality Sleep— The Double-Edged Sword of AlcoholResources Mentioned in This Episode:· Listen to Afternoon Snack: Exploring Common Relationships with Food + Alex's Half Ironman!· Listen to Afternoon Snack: Understanding Alcohol: Its Impact on Your Health and Lifestyle· Comparing Morning Exercise to No Exercise· Does Exercise Timing Impact Sleep?· The Bidirectional Relationship Between Diet Quality and Sleep· Do Alcohol Consumers Exercise More?────────────────────────────Want to work with Tactic Functional Nutrition? Check Out Our ServicesLearn More About Us Here and be sure to follow Tactic Nutrition on IG!Stay in the loop with us by signing up for our email list!
In this episode Lewis First, MD, MS, FAAP, editor-in-chief of Pediatrics, is back for “First Up.” He offers an overview of the March issue of the journal. David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak to Doctor Sean O'Leary, MD, MPH, FAAP, chair of the AAP Committee on Infectious Diseases, about the emerging measles crisis in the U.S. and the 2025 vaccine schedule. For resources go to aap.org/podcast.
In this episode Alex R. Kemper, MD, MPH, MS, FAAP, deputy editor of the journal Pediatrics, offers a bird's-eye view of the February issue. Hosts David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also talk to AAP President Susan J. Kressly, MD, FAAP, about how to help patients and families affected by Pediatric Acute Onset Neuropsychiatric Syndrome or PANS. For resources go to aap.org/podcast.
In this episode Rachel Moon, MD, FAAP, associate editor of digital media for the journal Pediatrics, shares a research roundup from the January issue. Hosts David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also talk to Bobbi Byrne, MD, FAAP, and Gary Freed, MD, MPH, FAAP, about pediatricians' income disparities based on sex. For resources go to aap.org/podcast.
In this episode Lewis First, MD, MS, FAAP, editor-in-chief of Pediatrics, is back for “First Up.” He offers a bird's-eye view of what's in the December issue of the journal. Hosts David Hill, MD, FAAP, and Joanna Parga-Belinkie, MD, FAAP, also speak with Kimberly Montez, MD, MPH, FAAP, about new policy from the AAP urging paid family and medical leave for all families. For resources go to aap.org/podcast.
Send us a textDo psychedelics make people more empathic? Does coming off antidepressants before psychedelic therapy affect outcomes? Can MDMA change your personality? Can a psychedelic medicine without the “trip” still help with depression? In today's episode of the Psychedelic Therapy Frontiers podcast, we discuss recent studies that seek to answer these questions and much more. For those of you who are new to the show, welcome! Psychedelic Therapy Frontiers is brought to you by Numinus and is hosted by Dr. Steve Thayer and Dr. Reid Robison.Learn more about our podcast at https://numinus.com/podcast/Learn more about psychedelic therapy training opportunities at https://numinus.com/training/Learn more about our clinical trials at https://www.numinus.com/clinical-trials Learn more about Numinus at https://numinus.com/Email us at ptfpodcast@numinus.com Follow us on Instagram: https://www.instagram.com/drstevethayer/https://www.instagram.com/innerspacedoctor/https://www.instagram.com/numinushealth/