glucose polymer used as energy store in animals
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In this episode, coach Daniel Rowland and myself each bring two recent research studies to the table that we have found interesting and potentially useful for athletes and coaches. We discuss the implications and practical takeaways of the findings, how athletes can implement the findings in practice, and the strengths and weaknesses of the different studies. Whether you listen for the love of endurance sports science, or because you want to keep up to date with the cutting edge in triathlon training, this one is for you. HIGHLIGHTS AND KEY TOPICS: A study looking into two types of torque training: very short maximal effort low-cadence sprints, and classic four-minute torque intervals just below Critical Power. Does ketone ester supplementation have direct performance-enhancing benefits? How age-group triathletes actually carb-loaded before the Ironman World Championships - did they hit the optimal amounts of carbohydrates or not? A review on the science of pacing, and practical takeaways including specific sessions to improve pacing. DETAILED EPISODE SHOWNOTES: We have detailed shownotes for all of our episodes. The shownotes are basically the podcast episode in written form, that you can read in 5-10 minutes. They are not transcriptions, but they are also not just surface-level overviews. They provide detailed insights and timestamps for each episode, and are great especially for later review, after you've already listened to an episode. The shownotes for today's episode can be found at https://scientifictriathlon.com/tts698/ LINKS AND RESOURCES: Daniel's Substack (Endurance: Ideas + Implementation) and website The Role of Pedaling Intensity During Torque Training in Cyclists: A Three‐Arm Randomized Controlled Trial - de Pablos et al. 2026 Post‐exercise ketone supplementation improves endurance performance and mitochondrial adaptations during an 8‐week endurance training intervention - Robberechts et al. 2026 From Intention to Execution: Pre-Race Nutrition Behaviours, Influences, and Performance Outcomes in Female Endurance Athletes at the IRONMAN® World Championships - Fortis et al. 2026 Developing negative split pacing in endurance athletes: practical guidelines and training models - Grivas et al. 2026 WHAT SHOULD I LISTEN TO NEXT? If you enjoyed this episode, I think you'll love the following related episodes: John Wakefield of Red Bull BORA hansgrohe – cycling coach and bike fitter | EP#465 - for more on torque training Carbohydrates – science and practice with Tim Podlogar, PhD | EP#354 - for more on carb loading Glycogen metabolism and optimising glycogen resynthesis with Bob Murray, PhD | EP#252 - for even more on carb loading Brendan Egan, PhD | EP#407 - for more on ketones Pacing science and training talk with Andy Renfree, PhD | EP#349 - for more on pacing You can find our full episode archives here, where you can filter for categories such as Training, Racing, Science & Physiology, Swimming, Cycling, Running etc. You can also find separate archives for specific series of episodes I've done, specifically Q&A episodes, TTS Thursday episodes, and Beginner Tips episodes. LEARN MORE ABOUT SCIENTIFIC TRIATHLON: The Scientific Triathlon website is the home of That Triathlon Show and everything else that we do Contact us through our contact form or email me directly (note - email/contact form messages get responded to much more quickly than Instagram DMs) Subscribe to our Newsletter Follow us on Instagram Learn more about our coaching, training plans, and training camps. We have something to offer for everybody from beginners to professionals. HOW CAN I SUPPORT THAT TRIATHLON SHOW (FOR FREE)? I really appreciate you reading this and considering helping the show! If you love the show and want to support it to help ensure it sticks around, there are a few very simple things you can do, at no cost other than a minute of your time. Subscribe to the podcast in your podcast app to automatically get all new episodes as they are released. Tell your friends, internet and social media friends, acquaintances and triathlon frenemies about the podcast. Word of mouth is the best way to grow the podcast by far! Rate and review the podcast (ideally five stars of course!) in your podcast app of choice (Spotify and Apple Podcasts are the biggest and most important ones). Share episodes online and on social media. Share your favourite episodes in your Instagram stories, start a discussion about interesting episodes on forums, reference them in your blog or Substack. SPONSORS: Precision Fuel & Hydration produce our favourite gels, sports drinks, and electrolyte and carbohydrate products here at That Triathlon Show and Scientific Triathlon. Use the free Fuel & Hydration Planner to get a personalised plan for your carbohydrate, sodium and fluid intake in your next event, and get 15% off your first 2026 order by using the code TTS2026 at checkout. Rouvy is hands down the most complete indoor cycling platform for triathletes. Among their thousands of beautiful bike courses from all around the world, all filmed in stunning quality, they have over 75 IRONMAN and IRONMAN 70.3 race courses plus 20+ Challenge Family courses, so you can pre-ride your race from home. Real gradients, real visuals, and real feel! Head to rouvy.com and use the code TTS to get your first month free on top of a 7-day free trial. Effortless Swimming produce the best swim goggles for triathletes and open water swimmers. Their NanoClear anti-fog lenses give you clear, fog-free vision that lasts and doesn't wear off. Don't let foggy or leaky goggles ruin another swim. Go to shop.effortlessswimming.com and use the code TTS15 to get 15% off your goggles, and get a free two-month Effortless Swimming course membership. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Are your current nutrition habits maximizing your gains, or are you inadvertently stalling your progress in the gym? This episode breaks down the exact science of hypertrophy, detailing how to optimize your daily macronutrient ratios to stimulate muscle protein synthesis and accelerate recovery. Discover the precise caloric thresholds, nutrient timing windows, and clean bulking frameworks required to pack on lean mass without adding unwanted body fat.
Welcome to the podddd! Today I am diving deep into how to eat to fuel your workouts and GROWI hope you enjoy, and don't forget to share and tag me on insta @emma.currivan xoxoCHAT TO ME ABOUT COACHING ON WHATSAPPJOIN MY PATREON HERE - just 5.99 a month hehe xTo submit a question for a Q&A episodeclick hereDon't forget to subscribe to my YouTube channel!Catch you in the next one xo00:00 Introduction and Podcast Upgrades01:24 Reflecting on Recent Life Events and Training Phase04:04 Managing Weight Gain During Building Phase05:55 Trusting the Process and Working with a Coach09:41 Overview of Nutrition for Muscle Gain and Performance11:28 Holistic Approach to Nutrition: Calories, Macros, and Micronutrients16:24 The Role of Carbohydrates and Glycogen in Training18:19 Importance of Dietary Fats and Hormonal Health20:13 Digestive Health and Nutrient Absorption23:55 Pre-Workout Nutrition Strategies29:05 Hydration and Electrolytes for Performance38:15 Post-Workout Nutrition for Recovery40:05 Eating for Long-Term Progress and Performance
A shorter monologue episode covering some questions that were submitted by you listeners. I also talk about some, what I believe to be, misconceptions that are floating around in sports nutrition these days. I hope you enjoy! For more free educational content and to see what services I provide, head over to my website @www.nutritionrundown.com
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Carbs, fueling, and metabolic efficiency – few topics create more confusion in endurance sports. Sports performance nutritionist Dani Hofstetter joins us to clear it up.Fresh off the release of his new book Train, Eat, Repeat, Dani shares a practical, no-BS approach to nutrition – cutting through the noise of extreme diets, high-carb trends, and supplement hype.You'll learn why most amateur athletes don't need 120g of carbs per hour, how pros actually fuel differently, and why training intensity, not just nutrition, determines your metabolism.This conversation goes beyond gels and grams per hour. It's about building a sustainable system that supports performance, recovery, and long-term health – without obsession or perfectionism.Whether you're an elite cyclist, racing ultras or Gran Fondos, or simply want to feel better on the bike, this episode will change how you think about fueling.What You'll LearnWhy most cyclists are undereating—not overeatingThe real difference between pro and amateur fueling needsHow training too hard kills fat metabolismWhy carbs are still misunderstood in endurance sportsThe truth about 90g vs 120g carbs per hourHow to structure nutrition for training days vs rest daysWhy perfectionism in nutrition can backfireThe biggest fueling mistakes causing GI issues and poor performanceCHAPTERS00:00 – Intro03:30 – Rapid fire: myths, carbs, and recovery05:30 – Hydration mistakes and GI issues06:20 – Why high performers often eat too little10:00 – Use it or lose it metabolism explained12:00 – Low-carb training and why it can backfire13:30 – Perfectionism in endurance athletes16:00 – Emotional + social role of food in performance18:30 – Why carbs are still misunderstood21:30 – Pro vs amateur fueling23:30 – Why amateurs shouldn't copy pro carb intake25:00 – The engine analogy: amateur vs pro physiology27:30 – How many carbs you actually need28:30 – Gut training and fueling strategy29:30 – Fat vs carbs: what really fuels performance31:00 – The athlete who tolerates more fuel wins33:00 – Why everyday nutrition matters more than supplements34:30 – Why low-carb training is outdated36:00 – Training zones mistakes (most athletes train too hard)37:30 – Why fat burning depends on intensity39:00 – Fasting: helpful or harmful for athletes?42:30 – Structuring nutrition: rest days vs hard days44:30 – Glycogen depletion and why recovery takes longer than you think47:00 – Why most athletes underfuel their week48:30 – The importance of planning nutrition49:00 – Post-ride mistakes50:00 – The real recovery window explained51:10 – Outro– LINKS –TRAIN EAT REPEAT - The Endurance Cookbookhttps://www.dorlingkindersley.de/buch/marlene-low-feride-dogum-dani-hofstetter-fabian-haefeli-train-eat-repeat-9783831050734PREVIOUS EPISODESSmart Nutrition for Hot Weather Ridinghttps://podcasts.apple.com/it/podcast/castelli-cycling-podcast/id1669906821?l=en-GB&i=1000722138953RED-S Ep. 1https://podcasts.apple.com/it/podcast/castelli-cycling-podcast/id1669906821?l=en-GB&i=1000671492861RED-S Ep. 2https://podcasts.apple.com/it/podcast/castelli-cycling-podcast/id1669906821?l=en-GB&i=1000672166132Sports Nutrition: Winter Training, Indoor Ridinghttps://podcasts.apple.com/it/podcast/castelli-cycling-podcast/id1669906821?l=en-GB&i=1000639782748Sports Nutrition: Race Day Fueling, Hydration Strategyhttps://podcasts.apple.com/it/podcast/castelli-cycling-podcast/id1669906821?l=en-GB&i=1000638271631Sports Nutrition: What is the Optimal Diet for Cycling Performancehttps://podcasts.apple.com/it/podcast/castelli-cycling-podcast/id1669906821?l=en-GB&i=1000636862451Sports Nutrition: Carbs, Fruits, Veggies for Everyday Performancehttps://podcasts.apple.com/it/podcast/castelli-cycling-podcast/id1669906821?l=en-GB&i=1000635636881– CONNECT –Dani HofstetterWebsite: https://danihofstetter.chInstagramhttps://www.instagram.com/dh_performance_nutrition/Host: Soren Jensenhttps://www.linkedin.com/in/sjensen77 Hosted on Acast. See acast.com/privacy for more information.
One of the most persistent myths in the health and fitness space is that fasting for more than a day or two causes the body to consume its own muscle tissue. It sounds scientific. It gets repeated by professionals. And the research says otherwise. The human body follows a fuel hierarchy. Glycogen burns first. Fat oxidation follows. Ketone bodies fuel the brain. A process called autophagy, which ramps up significantly between 24 and 72 hours of fasting, recycles damaged cellular components. Old proteins. Misfolded proteins. Precancerous cells. The body cleans the junk pile before it goes anywhere near functional muscle fiber. Growth hormone increases up to fivefold during extended fasts. Growth hormone is muscle protective. It signals the body to preserve lean mass and mobilize fat stores. The hormonal environment during a fast is actually more favorable for muscle preservation than a standard caloric deficit. A 2016 study published in the Journal of Translational Medicine found that subjects who fasted intermittently lost significantly more fat while retaining more muscle than subjects on standard caloric restriction. The mechanism is insulin. Caloric restriction keeps insulin elevated. The body never fully switches to fat burning. Fasting drops insulin to baseline and gives the body a clear metabolic signal. The fitness and supplement industries have a financial incentive to keep this information suppressed. You cannot sell meal plans, protein shakes, or supplements to someone who is not eating and whose growth hormone is already elevated naturally. I share this not as a medical professional but as someone in active food addiction recovery who has done the research because the stakes are personal. Full episode: https://youtu.be/Y3BGedhCYRc https://www.TheLastAddiction.com #Fasting #MetabolicHealth #Autophagy #FoodAddiction #AddictionRecovery #TheLastAddiction #ConnorsCut #ExtendedFasting #GrowthHormone #InsulinResistanceYoutube Channels:Conner with Honor - real estateHome Muscle - fat torchingFrom first responder to real estate expert, Connor with Honor brings honesty and integrity to your Santa Clarita home buying or selling journey. Subscribe to my YouTube channel for valuable tips, local market trends, and a glimpse into the Santa Clarita lifestyle.Dive into Real Estate with Connor with Honor:Santa Clarita's Trusted Realtor & Fitness EnthusiastReal Estate:Buying or selling in Santa Clarita? Connor with Honor, your local expert with over 2 decades of experience, guides you seamlessly through the process. Subscribe to his YouTube channel for insider market updates, expert advice, and a peek into the vibrant Santa Clarita lifestyle.Fitness:Ready to unlock your fitness potential? Join Connor's YouTube journey for inspiring workouts, healthy recipes, and motivational tips. Remember, a strong body fuels a strong mind and a successful life!Podcast:Dig deeper with Connor's podcast! Hear insightful interviews with industry experts, inspiring success stories, and targeted real estate advice specific to Santa Clarita.
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Welcome to Episode 128 of the Trail Running Ireland Podcast We have a coaching special this week with René Borg from Running Coach Ireland talking to us about a sweeping review from the famous South African Sports scientist Tim Noakes and his team asking whether we slow down because muscles run low on glycogen, or because the brain is protecting itself from falling blood sugar. Get ready guys for findings that could systematically dismantle more then 50 years of sports nutrition dogma.Everyone, get your running gear on, lets go. Link to Tim Noakes´ Research Paper that we discuss:https://academic.oup.com/edrv/advance-article/doi/10.1210/endrev/bnaf038/8432248?login=false
Plant-based fitness, vegan weight loss, and body recomposition over 50 in this episode, Maxime Sigouin sits down with Chuck Carroll to discuss his new book Forever Fit and how to get lean, strong, and healthy on a whole-food plant-based diet.Order a copy of my new book Forever Fit here - https://foreverfitbook.comWant to lose your next 3–5 lbs the sustainable way? Join my free 6-day email series where I break down exactly how to structure your workouts, nutrition, and habits if you are a plant-based eater over 50.
A thoughtful response to the recent Noakes et al. review questioning the role of carbohydrates in endurance performance. We explore why fatigue isn't caused by running out of muscle glycogen, why blood glucose protection is critical, and why that still doesn't explain elite fueling strategies. Using recent research and real-world endurance racing, we explain how carbohydrate availability supports mitochondrial throughput, late-race durability, and sustained power — even when glycogen isn't spared.
New year energy is great, but the real edge is calm, repeatable action. We open 2026 with a straight talk on travel, training, and why you probably didn't “gain 12 pounds of fat” last week. If you trained hard all year, a vacation can be strategic recovery—your tissues heal, your head clears, and you often return stronger. I share what I actually did on a family cruise: short, full-body sessions, over 10k steps a day, and a surprising shift toward nonalcoholic drinks despite buying the package. The goal wasn't martyrdom; it was feeling good and coming home ready to train.We dig into the mechanics of water weight and why the scale spikes after flights, salty meals, humidity, and higher carbs. Glycogen and water retention can swing your weight fast, then normalize once you're home, hydrated, and back in routine. The antidote to panic isn't punishment. It's a measured ramp: your normal training times, sensible loads, and one to two weeks of easing back so you avoid injury and reignite momentum. For travelers, we outline simple protocols—10 to 20 minute conditioning pieces, dumbbell push-pull-leg splits, and density sets that work in any hotel. Want more structure? Snap a photo of the hotel gym and we'll write you a week that fits the gear and your schedule.We also explain why we don't run January cash-grab challenges. Short sprints rarely become a lifestyle. Instead, we coach habit stacking that holds: three gym sessions a week, daily 10k steps, weighed protein, better sleep, then layered progress as the basics feel automatic. If alcohol or added sugar is derailing recovery, we offer practical ways to reduce the drag without killing your joy. And for an honest baseline, we're asking every member to get an InBody scan this month so we can adjust with real data, not emotions.If you're ready to trade “new year, new you” for steady you, this one's for you. Listen, subscribe, share it with a friend who travels for work, and drop a review telling us the one habit you'll lock in for the next 90 days.Follow us on Instagram here! https://www.instagram.com/doubleedgefitness/
This podcast summarizes glycogen metabolim hidhlighting some of the major differences between liver and muscle glycogenolysis. In addition, allosteric and hormonal regulation of glycogenolysis in both tissues are covered in detail.
Episode 168 - Zwift Racing, Snorkel Training, and Should You Be Increasing Lean Mass for Improved Glycogen Stores? Hello everyone. Welcome to the latest episode of The Matchbox Podcast powered by Ignition Coach Co. I'm your host, Adam Saban, and on this week's episode we talk about Zwift Racing, Snorkel Training, and whether or not you should be chasing those lean mass muscle gains in search of increased glycogen storage. As always, if you like what you hear, share this with your friends and leave us a five star review and if you have any questions for the show drop us an email at matchboxpod@gmail.com or head over to ignitioncoachco.com and fill out The Matchbox Podcast listener question form. Alight let's get into it! For more social media content, follow along @ignitioncoachco @adamsaban6 @dizzle_dillman @dylanjawnson @kait.maddox https://patreon.com/MatchboxPodcast?utm_medium=unknown&utm_source=join_link&utm_campaign=creatorshare_creator&utm_content=copyLink https://www.youtube.com/c/DylanJohnsonCycling https://www.ignitioncoachco.com https://www.youtube.com/@DrewDillmanChannel Intro/ Outro music by AlexGrohl - song "King Around Here" - https://pixabay.com/music/id-15045/ The following was generated using Riverside.fm AI technologies Summary In this conversation, the hosts discuss various aspects of Zwift racing, including training structure, the nature of Zwift races, and how to balance racing with endurance training. They also debunk the myth of snorkel training for fitness and explore the relationship between muscle mass and glycogen storage, concluding that while muscle mass can be beneficial, it may not significantly impact glycogen storage for endurance athletes. Chapters 00:00 Introduction to Zwift Racing and Training Structure 07:04 Understanding the Nature of Zwift Racing 11:36 Balancing Intensity and Recovery in Training 14:24 Exploring Snorkel Training and Breathing Techniques 14:45 Debunking Altitude Training Myths 17:34 Understanding Respiratory Training Devices 21:52 Evaluating the Efficacy of Snorkel Training 24:18 The Role of Muscle Mass in Glycogen Storage 27:33 Strength Training and Endurance Performance
We dig into a recent study showing a disconnect between equal muscle glycogen recovery and unequal high intensity interval performance due to delayed recovery fueling, despite equal total calories. We start with some background on glycogen's structure and the importance of fueling before discussing the outcomes and conclusions of this double blind, placebo-controlled crossover study before speculating on mechanisms and potential applications to trained cyclists, and connect it to common current nutrition practices.
Fueling for Performance: Avoid the Wall, Train Smarter & Live Better | Garage Gym Athlete Podcast Have you ever "hit the wall" mid-workout — or mid-day? In this episode, Jerred Moon and coaches Joe and Dave reveal how to fuel for performance using simple, science-backed strategies — whether you're training for a 100-mile ultra, crushing CrossFit, or just want more energy as a busy parent.
Professor Noakes has published more than 750 scientific books and articles. He has been cited more than 16 000 times in scientific literature, has an H-index of 74 and is rated an A1 scientist by the National Research Foundation of South Africa. After coming across research which denounced current international dietary guidelines as fallacy, Prof Noakes started researching the effects of carbohydrates, proteins and fats on the human race. His research convinced him that a high fat, low carb diet is the healthiest option for many. After being left frustrated by a decline in his personal health, Prof Noakes has made it his mission to reverse the global trend and redefine the dietary guidelines. The Noakes Foundation is the catalyst for this change. It seeks to reveal what genuine healthy nutrition looks like and, in doing so, make a difference in the lives of millions of people. Facebook: https://www.facebook.com/thenoakesfoundation/ https://www.facebook.com/EatBetterSA/ https://www.facebook.com/nutritionnetworkglobal/ X: https://x.com/TheNoakesF Youtube: https://www.youtube.com/channel/UC1ncpHCujYWS3yzB1C_tSbg Website: https://thenoakesfoundation.org/ https://thenoakesfoundation.org/eat-better-south-africa/ https://nutrition-network.org/ Timestamps: 00:00 Trailer 00:36 Introduction 10:01 Glycogen's role in metabolism 12:40 Carbs, fasting, and performance 19:04 Cycling vs running power output 26:14 Fat to glucose adaptation 31:32 Sodium balance and overhydration 32:45 Carbs and inflammation in athletes 40:07 Aging without losing performance 48:22 Muscle glycogen and carb balance 49:16 Carbohydrates, diabetes, and metabolism 56:58 Blood glucose performance effects 01:06:24 Carnivore diet for autoimmune healing Join Revero now to regain your health: https://revero.com/YT Revero.com is an online medical clinic for treating chronic diseases with this root-cause approach of nutrition therapy. You can get access to medical providers, personalized nutrition therapy, biomarker tracking, lab testing, ongoing clinical care, and daily coaching. You will also learn everything you need with educational videos, hundreds of recipes, and articles to make this easy for you. Join the Revero team (medical providers, etc): https://revero.com/jobs #Revero #ReveroHealth #shawnbaker #Carnivorediet #MeatHeals #AnimalBased #ZeroCarb #DietCoach #FatAdapted #Carnivore #sugarfree Disclaimer: The content on this channel is not medical advice. Please consult your healthcare provider.
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If you're an injured runner we can help you get back to running pain-free.Click the link to book a free call with ushttps://matthewboydphysio.com/booking/Running Fundamentals Coursehttps://matthewboydphysio.com/running-fundamentals-course/Instagramhttps://www.instagram.com/matthewboydphysio/SummaryIn this episode, Matthew Boyd discusses the significance of long runs in endurance training, emphasizing their role in glycogen depletion, muscle adaptation, and effective execution strategies. He explains the physiological changes that occur during long runs, the importance of fueling, and the differences between heart rate and pace as metrics for training. The conversation provides insights into how to optimize long runs for better performance and injury prevention.TakeawaysA long run is defined as any run longer than 90 minutes.Glycogen depletion is crucial for endurance training adaptation.Long runs stimulate muscle damage, leading to increased endurance capacity.Tissue resilience improves with long runs, helping prevent injuries.Heart rate is a better metric than pace for long runs.Aim for the middle of your heart rate and pace zones.Long runs should be executed in zone two for optimal benefits.Fueling during long runs is essential for performance.The risk of injury increases after three and a half hours of running.Understanding the balance between training stimulus and recovery is key.
We had a shocking change of feelings about shockingly ugly shoes before this amazing episode! The main topic was a pair of studies on energy expenditure and replenishment. The first was a case study that found massive energy needs beyond base metabolic rate for a full week after an ultra. We zoom out to discuss what that could mean for energy needs during hard training.The second study examined muscle v. liver glycogen replenishment, highlighting how difficult it can be to stay on top of energy needs. It also featured cod. Cod is a big theme in this episode.And this one was full of great topics! Other topics: treadmill workouts, an update on the ugly shoe debate from last week, our favorite probiotic and multivitamin, road supershoes for ultras, Tom Evans' fueling strategy at UTMB, how the use of pacing statistics may change the game, high-dose creatine to counter sleep deprivation, timing of big training weeks before races, heart rate zones v. feel, overcoming injury cycles, our theories for altitude performance, speed v. freshness in workouts, whether the pain cave exists in shorter events, using stairs in training, and lots more.This one was full of love, laughs, and cod. So much cod.May we all avoid being in the control group,-David and MeganClick "Claim Reward" for free credit at The Feed here: thefeed.com/swap For training plans, weekly bonus podcasts, articles, and videos: patreon.com/swapBuy the Kickr Run treadmill (code "SWAP"): https://www.wahoofitness.com/devices/running/treadmills/kickr-run-buyBuy Janji's amazing gear: https://janji.com/ (code "SWAP")
In this episode, we review the high-yield topic Glycogen Storage Disorders from the Pediatrics section at Medbullets.comFollow Medbullets on social media:Facebook: www.facebook.com/medbulletsInstagram: www.instagram.com/medbulletsofficialTwitter: www.twitter.com/medbulletsLinkedin: https://www.linkedin.com/company/medbullets
In this episode, Dr Joost Groen, a clinical biochemist at the University Medical Center Groningen, and Dr Matt Gentry, Professor & Chair of Biochemistry & Molecular Biology in the College of Medicine at University of Florida, join Rodrigo and Silvia to discuss new insights, AI, cancer metabolism and some of their favourite papers on Glycogen Storage Disorders. Authors opinions are their own and do not represent their institutions. GSD episode papers: Brain glycogen serves as a critical glucosamine cache required for protein glycosylation. Sun et al A machine learning model accurately identifies glycogen storage disease Ia patients based on plasma acylcarnitine profiles. Groen et al Small-molecule inhibition of glycogen synthase 1 for the treatment of Pompe disease and other glycogen storage disorders. Ullman et al Repurposing SGLT2 inhibitors: Treatment of renal proximal tubulopathy in Fanconi-Bickel syndrome with empagliflozin. Overduin et al Gross-Valle The relation between dietary polysaccharide intake and urinary excretion of tetraglucoside. Gross-Valle et al Glycogen drives tumour initiation and progression in lung adenocarcinoma. Clarke HA et al Spatial metabolomics reveals glycogen as an actionable target for pulmonary fibrosis. Conroy et al In situ mass spectrometry imaging reveals heterogeneous glycogen stores in human normal and cancerous tissues. Young et al Glycogen accumulation modulates life span in a mouse model of amyotrophic lateral sclerosis. Brewer et al Dynamics of cognitive variability with age and its genetic underpinning in NIHR BioResource Genes and Cognition cohort participants. Rahman MS et al Neurological glycogen storage diseases and emerging therapeutics Colpaert et al
This is a dive into research showing increased AMPK activation with low glycogen stores. We break down a paper discerning how AMPK does this, subsequent changes to AMPK's activity levels, and then come to some logical training conclusions. Along the way are some takeaways on interpreting and applying mechanistic research.
Welcome to The Peptide Podcast. Today we're going to talk about something that almost everyone on a GLP-1 journey hits eventually, the weight loss plateau. Thank you for listening to The Peptide Podcast. If you enjoyed the show and want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going. It starts like this: you begin a GLP-1 like semaglutide or tirzepatide, and for the first few weeks or months, the weight seems to fall off. You're eating less, not obsessing over food, and for the first time in a long time, it feels… easy. Then one day, the scale just stops moving. You're not doing anything different. You're still taking the meds. Still trying to eat well. Maybe you're walking more or lifting weights. But suddenly, nothing's happening—and the frustration kicks in. Sound familiar? Let's talk about what's really going on. 1. What Causes the Plateau? First of all, if you're in this place right now: you didn't mess up. GLP-1s are incredibly effective at reducing appetite and creating an initial calorie deficit, which is why people lose weight so quickly in the beginning. But your body isn't just going to let that continue unchecked. It adapts. This is called adaptive thermogenesis—a fancy way of saying your body becomes more efficient. You start burning fewer calories at rest than you did before. Your resting metabolic rate actually drops beyond what you'd expect just from losing weight alone. It's a survival mechanism. So what worked at the beginning—eating less and moving a bit more—might no longer be enough to keep the scale moving. This is totally normal. 2. Metabolism & Muscle: Why Strength Training Matters Now More Than Ever So now that we know why the plateau happens, let's talk about things we can do to help us get over it. Something that often gets overlooked but is absolutely critical—especially if you're on a GLP-1 or in any kind of calorie deficit. Resistance training is not optional. It's non-negotiable. Here's why. When you're losing weight—whether it's from a medication like semaglutide or just eating in a calorie deficit—your body isn't just pulling energy from fat. If you're not careful, it's also going to break down lean muscle tissue. And the more muscle you lose, the slower your metabolism gets. Why? Because muscle is metabolically active tissue. It burns calories even when you're doing absolutely nothing. So if you're not actively sending a signal to your body to keep that muscle, it'll start to let it go. That's where resistance training comes in. When you lift weights or do bodyweight exercises—think squats, push-ups, resistance bands, even heavy housework—you're telling your body: “Hey, I need this muscle. Don't burn it for fuel.” This is especially important for those on GLP-1s because these meds reduce appetite so significantly that you might not be eating enough protein—or enough calories in general—to maintain muscle without that extra stimulus. So if you've hit a plateau or want to prevent one, ask yourself: Am I strength training at least two to three times a week? Am I prioritizing movements that challenge large muscle groups—like legs, glutes, chest, and back? Am I fueling my workouts with enough protein? And let me be really clear, you don't have to become a gym rat. You don't have to lift crazy heavy weights. But you do have to move your muscles in a meaningful, consistent way. Protecting your lean mass is one of the best ways to keep your metabolism humming—not just during your weight loss journey, but after it too. Because this isn't about just losing weight—it's about building a strong, metabolically healthy body that can maintain that weight loss for life. 3. Mindset Check: The Plateau Is Not a Failure Now, let's get into the mental side of this journey—because it's just as important as nutrition, movement, and medication. One of the biggest challenges people face—especially when progress slows—is the mental roller coaster that comes with watching the scale. And I'll be honest: weighing yourself every single day is not ideal. Here's why. Your body weight naturally fluctuates. Daily. And those fluctuations have nothing to do with your actual fat loss or long-term progress. Instead, the number on the scale is influenced by things like: Hydration status – If you're slightly dehydrated, the scale may dip. But if you drank a ton of water the day before or had more salty food, it may go up due to water retention. Glycogen stores – When you eat carbs, your body stores them in your muscles and liver as glycogen, and for every gram of glycogen, your body stores about 3–4 grams of water. So a pasta dinner or even a healthy grain bowl can cause a temporary increase on the scale. Digestive contents – Let's be real: if you haven't had a bowel movement (constipation) or just ate a bigger meal, the scale might reflect that. Doesn't mean you gained fat. Inflammation or illness – If you're recovering from an illness, injury, or even a hard workout, your body retains extra water as part of the healing process. Again—temporary. But here's what happens when we don't understand this, we step on the scale, see a higher number, and panic. We question everything—“Am I doing something wrong? Is the medication not working? Should I eat less?” And that mindset spiral can lead to unnecessary stress, restriction, or even giving up. So what should you do instead? Focus on trends over time, not daily weigh-ins. Weigh yourself once a week at most, ideally at the same time of day, under the same conditions (like first thing in the morning before food or water). Or better yet—track non-scale victories: clothes fitting better, improved energy, reduced cravings, less inflammation, better digestion, even clearer skin. These are all signs your body is healing and progressing. Remember, your worth is not defined by a number, and fat loss is not always linear. There are ups, downs, pauses, and breakthroughs—and all of them are part of the process. 4. Habits: Recheck Your Routine Now, here's where we get really honest. Because as the months go by, it's normal for habits to loosen up. Maybe you're not tracking portions quite as closely. Maybe your steps have dropped. Maybe “just a bite” here and there has crept in more often than you realize. This doesn't make you bad or lazy—it makes you human. But if progress has stalled, it's worth revisiting the basics: Are you eating mostly whole, minimally processed foods? Are you staying hydrated and watching added sugars? Are you eating out frequently without paying attention to portions? Are you still moving your body every day? Small shifts can make a big difference. 5. Food Noise: Why It's Sneaking Back One of the most exciting things about GLP-1s is how much they reduce food noise—that constant mental chatter about snacks, cravings, and what's in the fridge. But for many people, that quiet doesn't last forever. Over time, especially as your body adapts to the medication or your dose levels off, food noise can return. You might find yourself thinking about food more often or wanting things you weren't craving before. This doesn't mean the med has stopped working. It means your biology is adjusting. What helps: Keeping meals protein-forward and fiber-rich Eating at regular times to avoid dips in energy or blood sugar Identifying emotional vs. physical hunger Managing stress and sleep, which both drive cravings This is the time to build real strategies—so you're not relying on the med alone. 6. Emotional Eating This brings me to my next point. Let's talk about something that often flies under the radar but can make a huge difference in your weight loss journey—emotional eating. This is when feelings like stress, boredom, anxiety, or sadness trigger you to eat, even if you're not physically hungry. It's totally normal, and many people experience this at some point. Now, GLP-1 medications like semaglutide or tirzepatide do a great job at reducing physical hunger by influencing hormones that control appetite. But they don't always fully address the emotional side of eating. So, even if your stomach feels satisfied, those emotional triggers can still push you toward cravings or eating for comfort. Recognizing emotional eating is the first step. Try to notice when you're eating because of feelings rather than hunger. Strategies like mindful eating, journaling your emotions, or finding alternative outlets—like walking, meditation, or chatting with a friend—can really help. If emotional eating is a big hurdle, working with a therapist or counselor who specializes in behavioral health can provide tools to manage those feelings without turning to food. Remember, managing emotional eating alongside your GLP-1 treatment can make a huge difference in overcoming plateaus and reaching your goals more sustainably. 7. Set Realistic Expectations: Fat Loss Isn't Linear Lastly, I want to talk about setting realistic expectations. I can't stress the following enough. You are not supposed to lose weight every single week forever. Your body needs breaks. Your metabolism needs to reset. And your mind needs time to adapt to this new version of you. Think of your fat loss journey like a staircase—not a slide. There are flat spots before the next drop. And guess what? Some of the most important changes—like maintaining your weight, building strength, or stabilizing your habits—happen during those flat spots. You don't need to push harder or go more extreme. You just need to keep showing up consistently. My Final Thoughts: Trust the Process The bottom line is trust the process. If you're on a GLP-1 and the scale has stalled, take a deep breath. This is a normal part of the process. It's not the end—it's just a signal to pivot and refocus. We want to build muscle. Prioritize protein. Revisit your habits. Stay active. And most importantly, don't give up. Thank you for listening to The Peptide Podcast. If you enjoyed the show and want to support what we do, head over to our Partners Page. You'll find some amazing brands we trust—and by checking them out, you're helping us keep the podcast going. Have a happy, healthy week!
The Diet Doc, LLC, is the parent company to many health, fitness, nutrition, and behavioral projects. Founded 25 years ago by Joe Klemczewski, PhD, known as the Godfather of Flexible Dieting, The Diet Doc is equipping the next generation of nutrition coaches. Joe has created the Flexible Dieting Institute, the FDI Professional Coach Association, the National Academy of Metabolic Science, the Nutrition Coaching Global Mastermind, the Life Mastery Podcast, Contest Prep University, and the Mind-Muscle Connection. Whether you're listening to a podcast or interview as a life transformation client, a physique sport competitor, a performance athlete, a fitness entrepreneur, or just need some life motivation, Joe won't disappoint! We hope you will explore what we offer and look for our free videos and articles at https://thedietdoc.com THE FLEXIBLE DIETING INSTITUTE playlist: https://www.youtube.com/playlist?list=PLaFD0Y6EtWHMDbJ2EZgGv6R_Ou_nEMQwZ THE SCIENCE OF STAGE-READY: CONTEST PREP UNIVERSITY playlist: https://www.youtube.com/playlist?list=PLaFD0Y6EtWHOqNOa5UFFs1QOH2CTrWw2W THE MIND-MUSCLE CONNECTION playlist: https://www.youtube.com/playlist?ist=PLaFD0Y6EtWHNAvcX9hmj7FHBNdWUa1GvE THE DIET DOC CONTEST PREP PROGRAM OPTIONS: https://thedietdoc.com/contest-prep SUBSCRIBE TO THIS CHANNEL: http://www.youtube.com/subscription_center?add_user=thedietdocweightloss HOW WE CAN HELP YOU IN YOUR FITNESS CAREER! * Become a member of the Flexible Dieting Institute Professional Coach Association and let us help you build an amazing career! www.fdi.coach * Become a National Academy of Metabolic Science Certified Nutrition Consultant: www.namscoach.com * Become a National Academy of Metabolic Science Physique Sport & Transformation Coach: www.namscoach.com LET'S CONNECT! Website: https://www.thedietdoc.com Facebook: https://www.facebook.com/joe.klemczewski Facebook: http://www.facebook.com/TheDietDoc Instagram: https://www.instagram.com/joeklemczewski
Download the FREE Precision Fat Loss Guide to choose one of 6 strategies designed for your experience, goals, and lifestyle:witsandweights.com/free--What if shifting WHEN you eat could accelerate your fat loss results?Most of us tackle dieting by reducing calories evenly each day, but research suggests there may be a more effective approach (and it's easy and even fun to implement).Learn about a fascinating study that tested weekend refeeds against traditional daily restriction... with surprising results for muscle preservation and how your metabolism slows down during weight loss.You'll discover how restructuring your weekly calories could significantly impact body composition outcomes, despite creating the same total weekly calorie deficit.Maybe it is about calorie timing after all!Main Takeaways:Traditional daily calorie restriction works, but research suggests strategic timing may offer muscle-preservation advantagesThe "Weekend Diet" approach maintains the same weekly deficit while distributing calories differentlyTargeted carbohydrate increases on specific days could help minimize metabolic adaptationPractical implementation requires careful calculation of weekly weight loss targetsEpisode Resources:Download my FREE Precision Fat Loss GuideTry MacroFactor for free with code WITSANDWEIGHTSLink to 2020 study by Campbell et al.Previous episode: The #1 Reason to Eat More CarbsTimestamps:0:00 - Traditional dieting vs. the "weekend diet" (carb refeeds) 7:39 - Findings on fat-free mass preservation 9:23 - Metabolic impacts beyond muscle preservation 10:22 - Carbs, insulin, and muscle protein synthesis12:02 - Anabolic signaling pathways 13:03 - Glycogen replenishment (training hard on Monday!) 15:44 - Psychological factors 16:38 - How to implement the Weekend Diet 21:32 - Leptin, refeeds, and hormones Support the show
Why Filling Your Glycogen Stores Matters More Than You Think “Have you ever found yourself doing everything right—eating clean, working out, staying disciplined—yet still feeling strangely off? Maybe you wake up in the middle of the night, your heart racing. Or you crash mid-afternoon despite your green smoothie. Or you carry a kind of low-grade tension that coffee can't fix and meditation can't melt. This article is for those moments when your body feels depleted, your cravings don't make sense, and your nervous system feels stuck in survival mode.” Learn why low glycogen stores—not lack of willpower—might be the missing piece, and how refueling your body can restore a sense of calm, clarity, and safety from the inside out. Written by Drs Alona and Matt at ConnectionDocs.com #vegan #plantbased #plantbasedbriefing #wfpb #lifestylemedicine #resistantstarches #starchyvegetables #starches #carbs ========================== Original post: https://connectiondocs.substack.com/p/why-filling-your-glycogen-stores ========================= Connection Docs is a multi-faceted practice devoted to holistic healing, vibrant health, and cultivating meaningful connections. “Our mission is to redefine how we approach health—empowering individuals, families, and communities to thrive. We believe that true wellness comes from aligning the mind, body, and spirit, and we are here to guide you in discovering your own path to vitality. Our practice offers a wide range of services designed to support your wellness journey. Whether you're seeking private coaching for personal growth, executive coaching to elevate your professional life, or online wellness courses to deepen your understanding of holistic health, we have something for everyone. Explore our e-books and calming devices for children, crafted to nurture resilience and ease and tune into our parenting podcast webe Parents. Explore our New York Times bestselling books or invite us to inspire your community through public speaking engagements. And don't miss our free weekly newsletter on Substack, filled with insights and practical tools on cultivating meaningful connections. Whatever your needs, Connection Docs is here to support and inspire you every step of the way.” Learn more at https://www.connectiondocs.com/ ============================== FOLLOW PLANT BASED BRIEFING ON: YouTube: https://www.youtube.com/@plantbasedbriefing Spotify: https://open.spotify.com/show/2GONW0q2EDJMzqhuwuxdCF?si=2a20c247461d4ad7 Apple Podcasts: https://podcasts.apple.com/us/podcast/plant-based-briefing/id1562925866 Your podcast app of choice: https://pod.link/1562925866 Facebook: https://www.facebook.com/PlantBasedBriefing LinkedIn: https://www.linkedin.com/company/plant-based-briefing/ Instagram: https://www.instagram.com/plantbasedbriefing/
(Wylder is now available on iOS + Android.)In this episode, Josh and Jesse Rich discuss the importance of nutrition for runners, particularly focusing on the week leading up to a race. They explore strategies for carb loading, the significance of glycogen, and how to optimize race day nutrition. Jesse emphasizes the need to balance fiber intake and carbohydrate consumption to ensure optimal performance without gastrointestinal distress. In this conversation, Jesse Rich and Josh discuss the critical role of nutrition in athletic performance, particularly in endurance sports. They explore carbohydrate loading, race nutrition strategies, and the importance of post-race recovery meals. The week before a race is crucial for nutrition, focusing on carb loading and fiber tapering.Glycogen is stored glucose that provides energy during races.Refined carbs are encouraged the week before a race to minimize fiber intake.A disciplined race nutrition strategy can prevent bonking and improve performance.---- Partners ----Wylder - Host and find Run Clubs, schedule public and private group runsNaked Sports Innovations - the worlds best hydration beltSalt Lake Footshills Trail Races. Salt Lake City, UT - May 31, 2025----Borderlands.cc | Instagram----Call RUNMORE649 (786-667-3649). Leave a message for the podcast—hot takes, agreement, anger, or joy.
Coach Chris explains the science behind bonking and outlines practical strategies to prevent it during long-distance triathlon, running or cycling events.She explains:• What bonking is and and why this extreme fatigue happens, often occurring around 3 hours into intense exercise• How much glycogen the body can store in calories and carbs• How many carbs to ingest per hour, depending on your gender, size and race distance. • Why two types of carbs are better than one (and which ones are currently being researched to push the gut) • Why heat decreases carbohydrate oxidation • Why your gut requires training just like your muscles• How your personalized fueling plan should be based on your sweat rate, body size, and event conditions • Why you should avoid trying anything new on race dayWant to go deeper and create your personalized fueling and hydration strategy based on your unique sweat? Get on the waitlist for our Fueling and Hydration Bootcamp at theenduranceedge.com/fuelingbootcamp to take the guesswork out of your fueling strategy and make your next race your best one yet. Support the showDownload our free resources: 6 Steps to Triathlon Success: Free Guide Hydration Guide for Athletes Runner's Fueling & Hydration Cheat Sheet Guide to High Performance Healthy Eating Find us here: TheEnduranceEdge.comRace with us: Humans of Steel Olympic & Sprint Triathlon at Harris Lake, NCPurchase Safe Supplements here.Follow us on Instagram or Facebook
Taking a little deep dive into low carb diets, how they work for weight loss and some common misconceptions around carbs in the nutrition space. Topics discussed on this episode: -What is a low-carb diet?-How do most-low carb diets work for weight loss?-Glycogen and water-weight fluctuations. -Difference between substrate utilization and actual net body fat loss.-How to decide what will work for you now + over the long term. + so many side tangents in-between. Where to find me: IG: @lukesmithrdCheck out my website HERETIA for listening!!
You're not going to gain much fitness in the last few days before a race but nailing your carb load can give a huge boost in performance. We're bringing together registered dietician Travis Wilson and running coach Andie Cozzarelli to help you master the art of the carb load with topics including: How long before race day you need to start increasing your carb intake How to know how many carbs your body needs Whether to focus on whole grains or fast-absorbing simple carbs like pasta and white bread Examples of what to eat at each point in the carb load as your race approaches How to fix common fueling problems like cramping and GI upset Making carbs your friend will help you to hit your paces for longer without feeling fatigued and Travis helps us to understand the science behind how this works. metpro.co 3 Ways to Effectively Carb Loading Before a Race - Runners Connect Glycogen Calculator - How Many Grams of Crabs you Need to Avoid Hitting the Wall Connect, Comment, Community Follow RunnersConnect on Instagram Join the Elite Treatment where you get first dibs on everything RTTT each month! Runners Connect Winner's Circle Facebook Community RunnersConnect Facebook page GET EXPERT COACHING AT RUNNERSCONNECT! This week's show brought to you by: Previnex Joint Health Plus Joint Health Plus from Previnex is clinically proven to reduce joint pain, joint stiffness,and improve joint flexibility in 7-10 days. In fact, it is clinically proven to be up to 5 times more beneficial than glucosamine and chondroitin alone or in combination. I saw immediate results when I started using Joint Health Plus and that's why I reached out to Previnex to see if we could put together an offer for you guys. If you're suffering from joint pain or simply want to get a jump start on protecting your joint health as you get older, head to runnersconnect.net/joint and use the code RTTT15 to save 15% on your first order. Pique We've done quite a few podcast episodes on the performance benefits of caffeine. But, if you're like many runners I know, pre-run coffee often leaves you with jitters or stomach issues. That's why I was so excited when I found Nandaka by Pique—the ultimate coffee alternative designed to power your runs, your training, and your recovery. So, what makes Nandaka different? Most so-called “coffee alternatives” don't actually provide functional energy. But Nandaka is built for endurance Unlike coffee, which spikes your energy and leaves you crashing mid-run, Nandaka fuels you with steady, sustained endurance—no spikes, no crashes, just clean energy that lasts. Nandaka provides its caffeine from fermented probiotic teas, which provide a slow-release caffeine that prevents jitters and gives you sustained release for those long runs workouts. It also contains cordyceps mushrooms, which help boost VO2 max, delivering more oxygen to your muscles for better endurance Plus, the probiotic teas mean no digestive distress like you often get with coffee. If you're tired of running on fumes—or worse, running on coffee crashes—it's time to make the switch. Right now, Pique is offering 20% off for life AND a free Starter Kit with your first purchase. Go to Piquelife.com/run and start running on real energy today. Your legs, your lungs, and your PRs will thank you
Glucose is the main source of energy for all forms of life, but it isn't usually stored as individual C6H12O6 molecules. Animals use glycogen to do that job. Glycogen is a large branched polymer of glucose molecules, linked together by α-1,4 and α-1,6 glycosidic bonds. The liver and muscles break down the stored glycogen whenever the body needs an extra boost of glucose. Glycogen storage diseases are genetic defects in glycogen metabolism resulting in accumulation of glycogen. What happens when macromolecules accumulate in cells? Cell damage and dysfunction. Because the liver and muscles are the two main organs that use glycogen, they are also the two most affected by glycogen storage diseases. In the liver, glycogen accumulation leads to hypoglycemia since the glycogen can't be broken down to glucose. Damage to the liver from extra glycogen can also lead to liver failure or even liver cancers. In the muscles, glycogen accumulation causes weakness, exercise intolerance, and potentially heart failure. There are at least 12 distinct glycogen storage diseases, but we'll cover only the 4 most common ones. After listening to this Audio Brick, you should be able to: Identify the most common glycogen storage diseases: von Gierke disease (type 1), Pompe disease (type 2), Cori disease (type 3), and McArdle disease (type 5). Identify the enzymes deficient in each of the most common glycogen storage diseases. Describe the clinical manifestations of each of the most common glycogen storage diseases. Describe management for each of the most common glycogen storage diseases. You can also check out the original brick from our Cellular and Molecular Biology collection, which is available for free. Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including nearly 800 Rx Bricks. After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology. *** If you enjoyed this episode, we'd love for you to leave a review on Apple Podcasts. It helps with our visibility, and the more med students (or future med students) listen to the podcast, the more we can provide to the future physicians of the world. Follow USMLE-Rx at: Facebook: www.facebook.com/usmlerx Blog: www.firstaidteam.com Twitter: https://twitter.com/firstaidteam Instagram: https://www.instagram.com/firstaidteam/ YouTube: www.youtube.com/USMLERX Learn how you can access over 150 of our bricks for FREE: https://usmlerx.wpengine.com/free-bricks/ from our Musculoskeletal, Skin, and Connective Tissue collection, which is available for free. Learn more about Rx Bricks by signing up for a free USMLE-Rx account: www.usmle-rx.com You will get 5 days of full access to our Rx360+ program, including nearly 800 Rx Bricks. After the 5-day period, you will still be able to access over 150 free bricks, including the entire collections for General Microbiology and Cellular and Molecular Biology.
Muscle Minds Podcast Dr Scott Stevenson & Scott McNally 0:00 SLU-PP-332 6:00 Understanding Mitochondrial Biogenesis 15:00 Intro 17:00 How do esters break down 24:00 Researching PEDs 29:00 The Best Role Models 36:00 Hitting Depth on Hacks without pain 41:00 Is SHBG a bad thing? Role of SHBG 45:00 Caber - Is it dangerous 53:40 Glycogen holding water 1:02:35 Growing Rear Delts ✅ Signed Copy of Be Your Own Bodybuilding Coach (15% goes to ASPCA) https://www.ebay.com/itm/205121965946
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In this episode, we review the high-yield topic of Glycogen from the Biochemistry section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets
***JOIN THE MASTER YOUR FASTING CHALLENGE THAT STARTS Dec. 11, 2024!*** New to fasting or want to get back on track? Struggling to break through a plateau? Ready to finally stop obsessing about your diet? Let's kick off spring time and prep for summer with intention, habit-building, and fast-tracking your fasting results! We'll GUIDE you how to FAST to LOSE FAT for good, and use 'fast cycling' to achieve uncommon results! Join us on March 20th for the Master Your Fasting Challenge! REGISTER HERE! Click the Link for DATES, DETAILS, and FAQs! DECEMBER 11th CHALLENGE REGISTRATION LINK In today's episode of the "Fasting for Life" podcast, we discuss the benefits and challenges of using fasting as a tool for health, focusing on the concept of flipping the metabolic switch, which involves transitioning the body from using glucose to ketones for energy. We highlight the importance of understanding ketosis, measuring ketone levels accurately using blood tests, and employing strategies such as proper hydration, controlled carbohydrate intake, and varied fasting durations to achieve metabolic flexibility. The episode also addresses common misconceptions about fasting, like the belief that longer fasts always lead to deeper ketosis, and offers practical tips for maximizing fat oxidation through high-intensity exercise and improved sleep quality. By incorporating these strategies, listeners can enhance their fasting journey, leading to improved body composition, cognitive function, and overall metabolic health. FREE RESOURCE - DOWNLOAD THE NEW BLUEPRINT TO FASTING FOR FAT LOSS! Learn how to RAMP UP into longer fasting windows! Gain insights into the non-weight loss benefits of fasting! Personalize your own fasting schedule and consistent FAT LOSS results! Get answers to what breaks a fast, how to break a fast, and tips and tricks to accelerate your fasting wins! THE BLUEPRINT TO FASTING FOR FAT LOSS DOWNLOAD Link to Berberine mentioned in this episode: https://us.fullscript.com/plans/ffl-berberine DOWNLOAD THE FASTING TRANSFORMATION JOURNAL HERE! Get your FREE BOX OF LMNT hydration support for the perfect electrolyte balance for your fasting lifestyle with your first purchase here! Get 30% off a Keto-Mojo blood glucose and ketone monitor (discount shown at checkout)! Click here! Let's continue the conversation. Click the link below to JOIN the Fasting For Life Community, a group of like-minded, new, and experienced fasters! The first two rules of fasting need not apply! Fasting For Life Community - Join HERE New to the podcast and wondering where to start? Head to the website and download our Fast Start Guide, 6 simple steps to put One Meal a Day Fasting (OMAD) into practice! Get our NEW sleep guide here! SLEEP GUIDE DIRECT DOWNLOAD If you enjoy the podcast, would you please tap on the stars below and consider leaving a short review on Apple Podcasts/iTunes? It takes less than 60 seconds, and it helps bring you the best original content each week. We also enjoy reading them! Research Links: https://keto-mojo.com/blog/intermittent-fasting-ketosis/?_kx=96u0JvQJ11AcA-dHzfAOyq3iRhgqKF0ZR5xcgH8sHjk.LpJ8Se https://onlinelibrary.wiley.com/doi/epdf/10.1002/oby.22065
Send us a textIn this episode, I'm stepping into the guest seat as Drew Shuman and I dive into the science and strategies behind optimizing health and performance. We explore how personalized practices, evidence-based biohacking, and a deeper understanding of your own physiology can transform your approach to well-being. This conversation is packed with actionable insights to help you take charge of your health journey.We cover a wide range of topics, including the cognitive and physical benefits of creatine, the role of carbohydrates in performance, and how to maximize VO2 max through strategic training. Drew and I discuss the importance of aligning your habits with your unique needs, demystifying complex health concepts, and providing practical advice for anyone looking to elevate their physical and mental performance.This episode is a must-listen for those curious about the intersection of science and health optimization. Whether you're starting your journey or looking for advanced strategies, you'll find plenty of inspiration and tools to create lasting change. Tune in to learn how to unlock your potential and embrace a healthier, more energized life.Looking to discover your science and optimize your life?APPLY FOR HEALTH OPTIMIZATION COACHINGhttps://calendly.com/andrespreschel/intro-call-with-andresLinks Mentioned in Today's Episode:Click HERE to save on BiOptimizers MagnesiumKey Points From This Episode:VO2 max and longevity [00:05:28]Energy currency of the body [00:09:02]Carbohydrate consumption and performance [00:13:39]Ketogenic diet benefits and concerns [00:15:05]Carbohydrates and exercise benefits [00:21:03]Glycemic index and exercise timing [00:23:16]Leptin signaling and obesity cycle [00:29:16]Fasted training effectiveness [00:30:48]Carbohydrate intake for performance [00:35:45]VO2 max and training adaptations [00:39:41]High altitude training benefits [00:42:19]Creatine: Evolving perceptions and benefits [00:48:07]Muscle gain versus fat loss [00:56:07]Creatine's impact on mood [00:59:22]Managing light exposure for sleep [01:00:41]Morning hydration and sunlight [01:05:02]Neuroplasticity and personal transformation [01:09:36]Leveraging physiological mechanisms for health [01:11:17]PeopleDrew ShumanInstagramPlacesLongevity Center, West Palm BeachOfficial WebsiteGreenfield Water SolutionsOfficial WebsiteEveryday Dose CoffeeProduct WebsiteRelight Electrolytes by Redmond Real SaltProduct WebsiteSupport the show
In this podcast episode, Cher and Carina discuss the realities of marathon training, focusing on weight fluctuation, nutrition, and the importance of strength training for runners. They share personal experiences and insights on how running affects body composition, the role of muscle and glycogen in weight changes, and the necessity of proper nutrition and recovery to support training. The conversation emphasizes the mental and physical challenges runners face, particularly regarding body image and performance, and advocates for strength training as a crucial component of a successful running regimen. In this conversation, Carina and Cher explore the complexities of marathon training, focusing on the importance of strength training, the impact of inflammation and recovery, and the significance of understanding body weight fluctuations during training cycles. They emphasize the need for runners to embrace their body's changes and recognize the diversity in body types that can lead to successful running performance.
Episode #175 In this Fasting Q&A episode, hosted by Coach Lisa Chance, Dr. Jason Fung answers questions from the TFM Community: Is sauerkraut OK for fat fasting or olives only? [03:10] What happens to the body weight set point when we are under stress? [04:11] I recently listened to a podcast from a few years ago where you and Dr. Peter Attia discussed insulin resistance. You said you had evolved your thinking about it and that it was not like a lock and key that didn't fit, but, instead, more like an overflow situation. You described it as a suitcase (the cell) already filled to the point of overflowing with shirts (the glucose), and it just couldn't hold any more, you just couldn't stuff anymore in. You also said that it is hyperinsulinemia that drives metabolic syndrome, not insulin resistance. Is that your current view? [12:13] Does an enema stimulate insulin? For example, a coffee enema with kefir, whey, or other added probiotics. [16:00] When we exercise, our bodies will pump out blood glucose to help with the energy needed. For an insulin resistant person doing hard, aerobic exercise (such as HIIT or run/walk), does the raised blood glucose need insulin to process it? [17:31] When a person is doing regular exercise routines, do they need to replenish glycogen stores after a workout or does the body do this on its own? [19:22] I read an article recently about SGLT inhibitors which said they can stimulate autophagy. Is this true? [24:33] Protein requirements are so confusing. If a person has a lot of weight to lose and they have a lot of excess skin (which is protein you want the body to use to minimize all that loose skin when you are done losing weight), how do they know how much protein to eat? Would they need less protein the more weight they had to lose? Does eating less protein force the body to use the loose skin? Does eating too much or too little protein have consequences? [27:40] I have read some things that say 8 ounces of animal products per week is enough and more than that has negative effects (insulin resistance, elevated bad cholesterol, and other things), and so getting more protein from legumes, nuts, and seeds is a good idea. Also, the type of animal products makes a difference; it is not just the processing, but whether it is organic, pasture-raised, regenerative, etc. I think that it can be easy to interpret that, since saturated fat isn't as bad as we thought, we might eat more animal products or not-so-healthy animal products, and, while it might lower insulin and promote weight loss in the short term, there can be other long-term effects that are not so healthy. Can you comment? [34:19] LINKS The two podcast episodes Lisa mentioned were: GLP-1s Episode #163 - Fasting Q&A with Dr Jason Fung: Order of Fat Burning, Fasting With a Gastric Sleeve, BMR Fluctuation, GLP-1 Drugs, and More https://www.thefastingmethod.com/podcast/2024/7/30/fasting-q-a-with-dr-jason-fung-order-of-fat-burning-fasting-with-a-gastric-sleeve-bmr-fluctuation-glp-1-drugs-and-more Hair Loss Episode #163 - Fasting Q&A with Nadia Pateguana, ND: Children and Snacking, Food Intolerances Since Fasting, Meals to Break a Fast, Hair Loss, and More https://www.thefastingmethod.com/podcast/2023/3/28/-fasting-q-a-children-and-snacking-food-intolerances-since-fasting-meals-to-break-a-fast-hair-loss-and-more- Please note that you need to be a member of the TFM Community to submit questions to the Q&A webinars with Dr. Fung but you can submit questions to our regular Q&A episodes here: https://bit.ly/TFMPodcastQs Transcripts of all episodes are available at www.thefastingmethod.com on the Podcast page. Learn More About Our Community: https://www.thefastingmethod.com Join our FREE Facebook Group: https://bit.ly/TFMNetwork Watch Us On YouTube: https://bit.ly/TFMYouTube Follow Us on Instagram: @fastingmethod This podcast is for educational purposes only and is not a substitute for professional care by a doctor or other qualified medical professional. You should always speak with your physician or other healthcare professional before doing any fasting, changing your diet, taking or adjusting any medication or supplements, or adopting any treatment for a health problem. The use of any other products or services purchased by you as a result of this podcast does not create a healthcare provider-patient relationship between you and any of the experts affiliated with this podcast. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.
- Join my weight loss coaching program - CLICK HERE TO LEARN MORE Join host Chris Terrell in a captivating episode of the Chris Terrell Podcast, where he shares his inspiring 125-pound weight loss journey through the power of modeling successful habits and routines. Chris highlights the importance of understanding lifestyle changes for sustainable weight loss and features an insightful conversation with his brother, David, discussing their differing philosophies on weight management. 00:00 Introduction and Host's Weight Loss Journey 01:16 Kicking Off a New Season 01:42 The Power of Modeling for Success 04:37 Applying Modeling to Personal Life 07:59 Conversation with My Brother on Weight Loss 09:58 Reflecting on Past Weight loss attempts 12:25 Understanding Different Perspectives on Weight Management 23:07 The Importance of Calorie Awareness 28:49 Balancing Rest and Activity 29:41 Indulging Without Guilt 31:36 The Impact of Diet on Performance 35:14 Parenting and Food Habits 37:44 Understanding Body Adaptation 47:55 The Role of Glycogen in Fitness 50:26 Reflecting on Weight Management 58:32 The Joy of Running in Nature 59:42 Podcast Wrap-Up and Listener Engagement — My Free Facebook Group My FREE Facebook Group: The CTC Weight Loss Support Group Learn about the Guild of Champions: Click here to learn more __ Three ways to support the show Support the show directly: Buy Me a Coffee Share your favorite episode on social media. Provide a review on your favorite podcasting app. — Free Downloads Download my Journaling Guide today: The Free Guide How to find your why: https://youtu.be/VkQtpSi1Tus — Additional Resources Coaching Website: www.christerrellcoaching.com Free Content: The Goods! My TikTok Channel: @og_chris_terrell Instagram: @OG_Chris_Terrell —
Today, we give you a little food for thought on day to day nutrition and race fueling. We sort of explore the traditional triathlon thinking process and ask if you're really doing what's right for your long term health. We get into how to think about what's working and how to recognize what's not. On some levels it's complex, but it can be really simple if you start putting yourself first in the equation. We talk about fitness over nutrition and how to build your body for long distance triathlon. We get into glycogen, fat oxidation, and ask if training your gut is really a logical approach. We look at bonking, periodizing carbs and ask you to think about how you're fueling and if it really makes sense. The modern diet is filled with synthetic ingredients and proving to be a failure. Are we as performance athletes falling into the same trap? Topics: Critically thinking about your nutrition day to day Do you believe something is wonky? Nutrition for triathlon Not just a triathlete, but a human The highest performers are willing to try anything to win The difference between an answer and an option Fueling for training and racing Most things are processed Enormous consumption of carbs and sugars Inflammation is at the root of most problems Glycogen depleted state for pros Fat oxidation rates Train your gut?? Fitness over nutrition Can you really burn all the calories? Are we searching for the wrong answers? Sugar crashes Training your body to crave more junk Bonking - just as much mental? Working hard all the time Periodizing carbohydrates Fat burning machines How to be much better on race day Heart palpitations Telling your body how to work Can you explain why you take in the calories you do? $8 a Gell to become more inefficient Popping pills Worshiping at the alter of your nutrition brand Mike Tarrolly - mike@c26triathlon.com Robbie Bruce - robbie@c26triathlon.com
Trong video này, bạn sẽ học được 4 từ khoá mới. Hãy viết xuống và tiếp tục nghiên cứu thêm nhé. (1) Nhịn ăn gián đoạn (2) Nhịn ăn gián đoạn hạn chế thời gian (3) Glycogen (4) Carbohydrate Bạn đã từng nghe về nhịn ăn gián đoạn nhưng chưa thực sự hiểu rõ về nó? ------ Linh đã thực hành nhịn ăn gián đoạn trong suốt 3 năm và sẽ chia sẻ những trải nghiệm thực tế của mình. Đồng thời Linh sẽ giúp bạn khám phá chủ đề này dưới góc nhìn khoa học và tìm hiểu xem điều gì sẽ xảy ra với cơ thể khi nhịn ăn
Muscle Minds Bodybuilding Podcast with Dr Scott Stevenson & Scott McNally Chapters: 00:00:00 - Thyroid Hormone Regulation and Metabolism 00:03:21 - Thyroid Hormone Conversion 00:07:24 - The Formation of Reverse T3 and T2 in Thyroid Hormone Metabolism 00:11:20 - Thyroid Replacement and T4 to T3 Conversion in the Body 00:15:21 - The impact of caloric deficit on T3 levels 00:18:56 - The Effect of Yohimbine on Insulin Levels 00:22:46 - The Role of Glycogen and Insulin in Fasted Cardio 00:26:18 - The Effects of Insulin Levels 00:29:36 - Training Variation and Deadlifts 00:33:04 - Learning Effects and Auto Regulation in Training 00:36:27 - Live Q&A and Personal Updates 00:40:38 - Coming off a Growth Cycle and Going into a Deficit 00:44:20 - The History of Steroids in Bodybuilding 00:47:39 - The Importance of Satellite Cells and Muscle Overlap 00:51:07 - Exercise Selection for Targeting Specific Muscle Groups 00:54:43 - Incorporating Deadlifts for Bicep and Trap Growth 00:58:10 - Arm Training and Overuse 01:01:36 - The Importance of Interpreting Lab Work Accurately 01:05:05 - Common Blood Work Issues and Misinterpretations 01:08:13 - The Importance of Specialized Medical Knowledge 01:11:44 - Effective Time Under Tension 01:15:07 - Creating Overload through Novelty 01:18:37 - Exploring Partial Reps ✅ Amino Asylum code THINK for 20% off research chems, peptides, l-carnitine and more https://aminoasylum.shop/ref/122/
Check out the full podcast here: https://youtu.be/-JGzN9XI3OM --- Support this podcast: https://podcasters.spotify.com/pod/show/evoqbike/support
Without glycogen, we couldn't go very far. Dr. Sullivan is a specialist in the glycogen molecule, which stores glucose, our energy source. In this podcast, he describes exciting discoveries and future research centered on glycogen presence that might help explain the connection between diabetes and kidney disease. Listen and hear answers to these questions and more: How does diabetes affect the kidneys? How do glycogen molecules differ in the liver of diabetic patients and why is that important? buy symbicort online buy symbicort over the counter online pharmacy What does glycogen do to the kidney that might lead to diabetic kidney disease stages? Mitchell Sullivan is pursuing a postdoc at the University of Queensland in a group that investigates glycation, diabetes, and how diabetic bodily systems handle extra glucose. Dr. Sullivan in particular follows glycogen formation in the organs. He's just setting out on a new study connecting diabetes and kidney health by focusing on glycogen presence in the kidneys of diabetics. Normally, glycogen is in the liver and muscle tissue, waiting to supply us with different kinds of energy needs. buy fildena online buy fildena over the counter online pharmacy But microscopy shows glycogen in the kidneys of diabetic patients that likely leads to damage and inflammation. The findings may lead to better therapeutics and prevention measures, from a more effective diabetes and kidney disease diet to medical interventions. buy aciphex online buy aciphex over the counter online pharmacy Listeners will have the privilege of hearing straight from Dr. Mitchell the hypothesis for this study that's just begun. He explains with clarity why the structure of this glycogen in diabetic kidneys differs from its normal form and is significantly insoluble in this form. Furthermore, it sticks together in clumps of starch-like granules in the thick ascending limb of the nephron. He's investigating if these cells that aren't accustomated to glycogen become overwhelmed and the glycogen gets stuck, leading to damage and inflammation that make for one of the common kidney failure causes. What's most interesting is that his PhD work on glycogen in the liver and muscle tissue of diabetics makes this hypothesis seem more likely. Listen in to hear why that's the case and more about this study that might bring scientists that much closer to improving diabetes and kidney health. To find out more about Dr. Mitchell's work, search his name in research aggregates, see his information page with Queensland University, and feel free to email him: mitchell.sullivan@mater.uq.edu.au. Available on Apple Podcasts: apple.co/2Os0myK
In this podcast, Dr. Berg talks about the relationship between the glycogen stores and electrolytes when doing ketogenic diet and intermittent fasting.
In this podcast, Dr. Berg talks about glycogen. Glycogen is the storage of sugar or glucose, glucose molecules strung connected together collectively. When you consume carbs, the body increases insulin and then starts storing glycogen. Then at a certain point, anything extra starts to be converted into fat. Glycogen can store only about 1700 calories. ADD YOUR SUCCESS STORY: https://bit.ly/3zZgZKm
Can science help you survive in the Arctic? Neil deGrasse Tyson and co-hosts Chuck Nice and Gary O'Reilly learn about what happens to the body during starvation and harsh conditions with survival doctor and contestant on S9 of Alone, Dr. Teimojin Tan. NOTE: StarTalk+ Patrons can listen to this entire episode commercial-free.Thanks to our Patrons Steve Duke, Jon Siegfreid, Pau Vogel, Luis, Eric Weaver, and David H. Carroll for supporting us this week.Photo Credit: Christian Uhlig, CC BY 3.0, via Wikimedia Commons
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