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In this week’s episode of The Health Advocates, host Steven Newmark unpacks a whirlwind of health news that could reshape the foundation of U.S. public health. From a major lawsuit against HHS Secretary Robert F. Kennedy Jr. to record-high measles cases and the quiet cancelation of a critical preventive care meeting, Steven explains what’s at stake. Plus, he shares a hopeful update on bird flu and the importance of defending science-based health policy amid political disruption. Among the highlights in this episode: 00:56: Steven explains the lawsuit against HHS Secretary RFK Jr. for bypassing CDC and ACIP (Advisory Committee on Immunization Practices) input in changing COVID-19 vaccine guidance 01:33: Steven emphasizes how sidelining scientific advisors erodes public health trust and transparency 02:02: Measles cases hit a 30-year high; Steven explores how vaccine hesitancy has contributed to this preventable public health failure 02:47: Steven discusses how vaccine misinformation puts vulnerable groups like children and immunocompromised people at risk 03:06: Steven shares encouraging news: the CDC has ended its emergency response to the bird flu outbreak due to declining animal infections 03:36: Steven explains how a well-functioning public health system should respond to outbreaks like H5N1 04:11: A last-minute cancellation of the U.S. Preventive Services Task Force meeting raises concerns about potential political interference 04:37: Steven connects this move to a recent Supreme Court ruling that allows the HHS Secretary to replace members of this influential panel 04:47: Steven warns that this could lead to fewer no-cost preventive services covered by insurance under the ACA 05:12: Steven announces the new season of Let’s Get Personal, which focuses on rheumatoid factor levels in RA. Tune in to the new episodes and explore our related resources at: https://creakyjoints.org/lets-get-personal/ Contact Our Host Steven Newmark, Chief of Policy at GHLF: snewmark@ghlf.org A podcast episode produced by Ben Blanc, Director, Digital Production and Engagement at GHLF. We want to hear what you think. Send your comments in the form of an email, video, or audio clip of yourself to podcasts@ghlf.org Catch up on all our episodes on our website or on your favorite podcast channel.See omnystudio.com/listener for privacy information.
Good morning from Pharma and Biotech daily: the podcast that gives you only what's important to hear in Pharma e Biotech world.The FDA has recently released over 200 complete response letters (CRLs) as part of its initiative to enhance transparency regarding the reasons behind the rejection of new drug and biologics applications. This effort reflects the agency's commitment to being more open with the public about its decision-making processes.In other news, AbbVie has made a significant acquisition by purchasing Ichnos Glenmark's lead myeloma antibody for nearly $2 billion, including a substantial upfront payment of $700 million. However, Ultragenyx and Mereo Biopharma faced challenges as their stocks declined following the announcement that the phase II/III study of their osteogenesis imperfecta candidate did not yield strong results during an interim analysis.Furthermore, there is growing concern surrounding the potential dismissal of the U.S. Preventive Services Task Force, following a Supreme Court ruling that affirmed Health Secretary Robert F. Kennedy Jr.'s authority to remove its members at his discretion. This development has raised questions about the future of preventive health initiatives in the country.For drug developers, finding the right balance between speed and quality is essential for achieving success in the industry. To optimize processes and leverage technology throughout the development journey, new digitization strategies are being explored. Embracing these advancements can help streamline operations and enhance overall efficiency in drug development efforts.
The U.S. Supreme Court closed out its session before breaking for summer on Friday, ruling that decisions around coverage of HIV PrEP drugs should be left up to the U.S. Preventive Services Task Force. The ruling thwarted a lawsuit brought by a group of insurance providers who challenged the Affordable Care Act's requirement that they cover preventive medicines, such as HIV drugs, recommended by the task force. The high court also determined that members of this task force can be removed at will by HHS Secretary Robert F. Kennedy Jr.Speaking of HHS committees from which members have been removed at will by Kennedy, the CDC's revamped Advisory Committee on Immunization Practices convened last week for its first meeting since the roster overhaul, where a vote on Merck's recently approved RSV-targeting monoclonal antibody Enflonsia and a discussion around the inclusion of preservative thimerosal in influenza vaccines was on the docket, but an expected vote on Moderna's mRNA-based RSV shot mRESVIA was not.Also dominating the headlines on Friday was the FDA's decision to remove the Risk Evaluation and Mitigation Strategies (REMS) program from the six approved CAR T therapies it was applied to. Analysts and patient groups lauded the move, which is expected to potentially double access to these life-saving therapies, saying it reflects “thoughtful consideration of real-world evidence” and “regulatory trust.”Willliam Blair noted that it could be a “positive signal” to companies developing CAR T therapies for autoimmune diseases, which now includes AbbVie. In an all-cash buyout on Monday, the Illinois-based pharma dropped $1.2 billion for Capstan Therapeutics and its in vivo edited CAR T therapy for B cell–mediated autoimmune diseases. M&A has been on an uptick of late, and private equity companies—such as those that snapped up bluebird bio—are also getting in on the game.Finally, after Lykos Therapeutics' high profile failure last summer, the psychedelics space is heating up once again. While a Phase III readout of Compass Pathways' psilocybin drug last week in treatment-resistant depression received a muted reaction from investors, the response to a Phase II readout for Beckley Psytech and atai Life Sciences' intranasal psychedelic was more positive.
In the latest episode of Ask Michelle, Michelle shared key compliance updates, including the upcoming April Supreme Court ruling on the U.S. Preventive Services Task Force's (USPSTF) authority over preventive care recommendations, the San Francisco Health Care Security Ordinance (HCSO) annual reporting deadline on May 2, 2025, and President Trump's recent Executive Order aimed at lowering drug costs. Michelle also highlighted the upcoming Fisher Phillips webinar on April 30, 2025, covering the latest in labor and employment law.Michelle addressed several listener questions, such as whether beneficiaries are taxed if an employer fails to impute income on excess group term life insurance, the requirement to issue a Summary of Material Modifications (SMM) after a plan and carrier change on January 1, 2025, and if fully insured group health plans must conduct a Non-Quantitative Treatment Limitation (NQTL) analysis for Mental Health Parity compliance.She also discussed the rise in class action lawsuits against employer wellness programs related to tobacco surcharges and reminded listeners about the BCBS Provider Settlement Fund claims deadline of July 29, 2025. Are you curious about a compliance issue? Please submit your questions to AskMichelle@imacorp.com, and Michelle will answer them in the next episode.
Issue(s): Whether the U.S. Court of Appeals for the 5th Circuit erred in holding that the structure of the U.S. Preventive Services Task Force violates the Constitution's appointments clause and in declining to sever the statutory provision that it found to unduly insulate the task force from the Health & Human Services secretary's supervision. ★ Support this podcast on Patreon ★
In Kennedy v. Braidwood Management, Inc. the Supreme Court will consider "Whether the U.S. Court of Appeals for the 5th Circuit erred in holding that the structure of the U.S. Preventive Services Task Force violates the Constitution's appointments clause and in declining to sever the statutory provision that it found to unduly insulate the task force from the Health & Human Services secretary’s supervision."In Kennedy v. Braidwood Management, Inc., several Christian-owned businesses, along with six individuals in Texas, brought suit alleging that the Affordable Care Act's preventative services coverage requirement was illegal and unconstitutional. They contend it violates the Religious Freedom Restoration Act, as the ACA required them to fund preventative services that conflicted with their religious beliefs, and that it violates the Constitution’s Appointments Clause, given the controlling effect of a non-appointed advisory body over which preventative treatments were required. Given those issues, the case sits at an interesting intersection of health law, religious liberty law, and administrative procedure, and the Supreme Court is set to hear oral argument on April 21, 2025.Join us for a Courthouse Steps program where we break down and analyse how oral argument went before the Court.Featuring:Timothy Sandefur, Vice President for Legal Affairs, Goldwater Institute
This Day in Legal History: Mutiny on the BountyOn April 28, 1789, one of the most famous acts of rebellion at sea occurred aboard the HMS Bounty. Captain William Bligh and 18 loyal crew members were forcibly set adrift in the Pacific Ocean by mutineers led by Fletcher Christian. The incident exposed deep tensions over leadership, working conditions, and authority in the Royal Navy. British law at the time treated mutiny as a capital offense, reflecting the critical importance of discipline aboard ships. After the mutiny, an intense search for the culprits began, with some mutineers eventually captured and returned to England to stand trial.The ensuing court-martial proceedings offered early insight into naval justice and the balancing act between maintaining strict command and recognizing crew grievances. Defendants argued that Bligh's harsh leadership provoked the uprising, but the Admiralty was unwavering in its stance against insubordination. Of those captured, three were found guilty and hanged, while others were acquitted or pardoned. The legal handling of the mutiny reinforced the severe consequences for undermining maritime authority. It also prompted discussions about humane treatment of sailors, subtly influencing later reforms in naval discipline.The Mutiny on the Bounty became a lasting symbol in both legal and cultural history, illustrating how law functions as both a tool of control and a response to the realities of human endurance and dissent at sea.Seven Democratic senators on the U.S. Senate Judiciary Committee have requested information from the Justice Department regarding recent changes within its civil rights division under President Donald Trump's administration. In a letter sent Friday, they expressed concern over the reassignment of several career officials, suggesting these moves could be an attempt to pressure staff into leaving and shift the division's enforcement priorities. Since Trump's return to office and the appointment of Pam Bondi as Attorney General, the department has paused investigations into police misconduct, launched a gun rights investigation in Los Angeles, and altered its approach to transgender rights cases. It has also opened investigations into antisemitism related to pro-Palestinian protests at colleges. The senators emphasized the importance of nonpartisan career staff in maintaining the integrity of civil rights enforcement. About a dozen senior attorneys specializing in voting, police, and disability rights were among those reassigned. The Justice Department has not yet commented on the senators' letter.Democratic senators question US Justice Department on civil rights changes | ReutersThe U.S. Drug Enforcement Administration announced that federal law enforcement agencies raided a nightclub in Colorado Springs, arresting over 100 individuals who were in the U.S. illegally. The operation resulted in 114 arrests out of more than 200 people present at the venue, making it one of the largest immigration-related raids since President Donald Trump's second term began. Attorney General Pam Bondi stated that the raid also led to the seizure of cocaine, methamphetamine, and "pink cocaine," and two individuals were arrested on outstanding warrants. Bondi mentioned links to gangs like Tren de Aragua and MS-13, although she did not directly confirm whether those arrested were affiliated with them. The DEA noted that occupants were given multiple warnings before the raid was executed. This action is part of an intensifying crackdown on illegal immigration under Trump's renewed immigration policies. Separately, ICE recently reported nearly 800 immigration-related arrests in Florida during a multi-agency operation.Over 100 migrants in the US illegally arrested in Colorado nightclub | ReutersThe Supreme Court has requested additional briefing in a case challenging the Affordable Care Act's mandate that insurers cover preventive services, like cancer screenings, at no cost. The justices specifically want the parties to address whether the Secretary of Health and Human Services has the legal authority to appoint members of the U.S. Preventive Services Task Force, which advises on covered treatments. During arguments on April 21, Justice Neil Gorsuch questioned whether the power to remove officials necessarily implies the power to appoint them, an issue the lower court had not considered. The Fifth Circuit Court of Appeals previously ruled that the task force's structure violated the Constitution's appointments clause, arguing its members must be nominated by the president and confirmed by the Senate. The Trump administration contends the task force members are merely "inferior officers" under the HHS Secretary's control. The case also involves objections by Texas businesses and residents to mandatory coverage of HIV prevention drugs, claiming unconstitutional imposition by unelected officials. Supplemental briefs are due by May 5, and while rare, this is not the first time the Court has asked for more information after oral arguments, as seen in past cases like Zubik v. Burwell and Citizens United v. FEC.Supreme Court Orders New Briefs After Obamacare Case Argued (1) This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit www.minimumcomp.com/subscribe
When a public school adds stories with LGBT themes to its elementary reading curriculum, do religious parents have a First Amendment right to opt out? And did ObamaCare evade a constitutional check when it delegated power to the Preventive Services Task Force? The Supreme Court debates those points in Mahmoud v. Taylor and Kennedy v. Braidwood Management. Learn more about your ad choices. Visit megaphone.fm/adchoices
Each month, a panel of constitutional experts convenes to discuss the Court’s upcoming docket sitting by sitting. The cases covered in this preview are listed below.Kennedy v. Braidwood Management (April 21) - Appointments Clause; Issue(s): Whether the U.S. Court of Appeals for the 5th Circuit erred in holding that the structure of the U.S. Preventive Services Task Force violates the Constitution's appointments clause and in declining to sever the statutory provision that it found to unduly insulate the task force from the Health & Human Services secretary’s supervision.Parrish v. United States (April 21) - Federal Civil Procedure; Issue(s): Whether a litigant who files a notice of appeal after the ordinary appeal period under 28 U.S.C. § 2107(a)-(b) expires must file a second, duplicative notice after the appeal period is reopened under subsection (c) of the statute and Federal Rule of Appellate Procedure 4.Commissioner of Internal Revenue v. Zuch (April 22) - Taxes; Issue(s): Whether a proceeding under 26 U.S.C. § 6330 for a pre-deprivation determination about a levy proposed by the Internal Revenue Service to collect unpaid taxes becomes moot when there is no longer a live dispute over the proposed levy that gave rise to the proceeding.Mahmoud v. Taylor (April 22) - Religious Liberties, Education Law, Parental Rights; Issue(s): Whether public schools burden parents’ religious exercise when they compel elementary school children to participate in instruction on gender and sexuality against their parents’ religious convictions and without notice or opportunity to opt out.Diamond Alternative Energy LLC v. EPA (April 23) - Standing, Redressibility; Issue(s): (1) Whether a party may establish the redressability component of Article III standing by relying on the coercive and predictable effects of regulation on third parties.Soto v. United States (April 28) - Financial Procedure; Issue(s): Given the U.S. Court of Appeals for the Federal Circuit’s holding that a claim for compensation under 10 U.S.C. § 1413a is a claim “involving … retired pay” under 31 U.S.C. § 3702(a)(1)(A), does 10 U.S.C. § 1413a provide a settlement mechanism that displaces the default procedures and limitations set forth in the Barring Act?A.J.T. v. Osseo Area Schools, Independent School District No. 279 (April 28) - ADA; Issue(s): Whether the Americans with Disabilities Act of 1990 and Rehabilitation Act of 1973 require children with disabilities to satisfy a uniquely stringent “bad faith or gross misjudgment” standard when seeking relief for discrimination relating to their education.Martin v. U.S. (April 29) - Supremacy Clause, Torts; Issue(s): (1) Whether the Constitution’s supremacy clause bars claims under the Federal Tort Claims Act when the negligent or wrongful acts of federal employees have some nexus with furthering federal policy and can reasonably be characterized as complying with the full range of federal law; and 2) whether the discretionary-function exception is categorically inapplicable to claims arising under the law enforcement proviso to the intentional torts exception.Laboratory Corporation of America Holdings v. Davis (April 29) - Civil Procedure; Issue(s): Whether a federal court may certify a class action pursuant to Federal Rule of Civil Procedure 23(b)(3) when some members of the proposed class lack any Article III injury.Oklahoma Statewide Charter School Board v. Drummond (April 30) Establishment Clause, Education Law, Federalism and Separation of Powers; Issue(s): (1) Whether the academic and pedagogical choices of a privately owned and run school constitute state action simply because it contracts with the state to offer a free educational option for interested students; and (2) whether a state violates the First Amendment's free exercise clause by excluding privately run religious schools from the state’s charter-school program solely because the schools are religious, or instead a state can justify such an exclusion by invoking anti-establishment interests that go further than the First Amendment's establishment clause requires. Featuring: Thomas A. Berry, Director, Robert A. Levy Center for Constitutional Studies, Cato InstituteProf. Brian T. Fitzpatrick, Milton R. Underwood Chair in Free Enterprise, Vanderbilt University Law SchoolSarah Parshall Perry, Vice President & Legal Fellow, Defending EducationTim Rosenberger, Fellow, Manhattan InstituteProf. Gregory Sisk, Pio Cardinal Laghi Distinguished Chair in Law, Professor and Co-director of the Terrence J. Murphy Institute for Catholic Thought, Law, and Public Policy, University of St. Thomas School of LawFrancesca Ugolini, Former Chief, DOJ Tax Division, Appellate Section(Moderator) Elle Rogers, General Counsel, United States Senator Jim Banks
Administrative Law: Does the U.S. Preventive Services Task Force violate the Appointments Clause? - Argued: Mon, 21 Apr 2025 11:23:10 EDT
A case in which the Court will decide whether the structure of the U.S. Preventive Services Task Force violates the Constitution's Appointments Clause, and whether the provision that insulates the task force from the Health & Human Services secretary's supervision is severable from the rest of the statute.
In the latest episode of Ask Michelle, Michelle provided crucial updates, including the upcoming April Supreme Court ruling regarding the U.S. Preventive Services Task Force's (USPTF) authority on preventative care recommendations, the San Francisco Health Care Security Ordinance (HCSO) annual reporting deadline of May 2, 2025, and the CMS 2025 Marketplace Integrity and Affordability Proposed Rule. Michelle also addressed listener questions, such as the legality of adding an international prescription drug sourcing program to a self-funded medical plan, the necessity of issuing a Summary of Material Modifications (SMM) after a plan and carrier change on January 1, 2025, and whether a fully insured group health plan needs to conduct a Non-Quantitative Treatment Limitation (NQTL) analysis for MHPAEA compliance. Are you curious about a compliance issue? Please submit your questions to AskMichelle@imacorp.com, and Michelle will answer them in the next episode.
A Survivor's Call to Action: Understanding Colorectal CancerThe discussion centers on the critical importance of colorectal cancer awareness, particularly during the month dedicated to its recognition. I emphasize the significance of early detection, underscoring that the survival rate markedly improves when the disease is identified at its localized stage. With colorectal cancer being the second leading cause of cancer-related mortality in the United States, it is paramount for individuals to engage in regular screenings, which the U.S. Preventive Services Task Force recommends starting at the age of 45. Moreover, I highlight the alarming increase in colorectal cancer incidence among adults under 50, which necessitates urgent attention and advocacy for improved healthcare access. The Colorectal Cancer Alliance plays a vital role in this endeavor, providing resources, education, and support to patients and their families while advocating for necessary policy changes.Takeaways: Colorectal Cancer Awareness Month is crucial for educating the public about this disease. Early detection significantly enhances survival rates, particularly when cancer is diagnosed at a localized stage. Regular screenings for colorectal cancer should commence at age 45, or earlier for those at higher risk. The Colorectal Cancer Alliance provides vital resources and support for patients and their families. Awareness and education efforts are essential in combating the rising incidence of colorectal cancer among younger adults. Participating in events and sharing information can greatly contribute to colorectal cancer advocacy and research funding. Links referenced in this episode:ratethispodcast.com/resessions
Episode 183: Colorectal Cancer in Young AdultsFuture Dr. Avila and Dr. Arreaza present evidence-based information about the screening and diagnosis of colorectal cancer and explain the increasing incidence among young adult and the importance to screen early in high risk groups. Written by Jessica Avila, MS4, American University of the Caribbean School of Medicine. Edits and comments by Hector Arreaza, MD.You are listening to Rio Bravo qWeek Podcast, your weekly dose of knowledge brought to you by the Rio Bravo Family Medicine Residency Program from Bakersfield, California, a UCLA-affiliated program sponsored by Clinica Sierra Vista, Let Us Be Your Healthcare Home. This podcast was created for educational purposes only. Visit your primary care provider for additional medical advice.IntroductionJessica: Although traditionally considered a disease only affecting older adults, colorectal cancer (CRC) has increasingly impacted younger adults (defined as those under 50) at an alarming rate. According to the American Cancer Society, CRC is now the leading cause of cancer-related death in men under 50 and the second leading cause in women under 50 (American Cancer Society, 2024). Arreaza: Why were you motivated to talk about CRC in younger patients?Jessica: Because despite advancements in early detection and treatment, younger patients are often diagnosed at later stages, resulting in poorer outcomes. We will discuss possible causes, risk factors, common symptoms, and why early screening and prevention are important. Arreaza: This will be a good reminder for everyone to screen for colorectal cancer because 1 out of every 5 cases of colorectal cancer occur in adults between the ages of 20 and 54. The Case of Chadwick BosemanJessica: Many people know Chadwick Boseman from his role as T'Challa in Black Panther. His story highlights the worrying trend of increasing CRC in young adults. He was diagnosed with stage III colorectal cancer at age 39. This diagnosis was not widely known until he passed away at 43. His case shows how silent and aggressive young-onset CRC can be. Like many young adults with CRC, his symptoms may have been missed or thought to be less serious issues. His death drew widespread attention to the rising burden of CRC among young adults and emphasized the critical need for increased awareness and early screening efforts.Arreaza: Black Panther became a hero not only in the movie, but also in real life, because he raised awareness of the problem in young AND in Black adults. EpidemiologyJessica: While rates of CRC in older populations have decreased since the 1990s, adults under 50 have seen an increase in CRC rates of nearly 50%. (Siegel et al., 2023). Currently, one in five new CRC diagnoses occurs in individuals younger than 55 (American Cancer Society, 2024).Arreaza: What did you learn about the incidence by ethnic groups? Are there any trends? Jessica: Yes, certain ethnic groups are shown to have higher rates of CRC. Black Americans, Native Americans, and Alaskan Natives have the highest incidence and mortality rates from CRC (American Cancer Society, 2024). Black Americans have a 20% higher incidence and a 40% higher mortality rate from CRC compared to White Americans, primarily due to disparities in access to screening, healthcare resources, and early diagnosis. Hispanic and Asian American populations are also experiencing increasing CRC rates, though to a lesser extent.Arreaza: It is important to highlight that Black Americans have the highest rate of both diagnoses and deaths of all groups in the United States. Who gets colorectal cancer?Risk FactorsJessica: Anyone can get colorectal cancer, but some are at higher risk. In most cases, environmental and lifestyle factors are to blame, but early-onset CRC are linked to hereditary conditions. Arreaza: There is so much to learn about colorectal cancer risk factors. Tell us more.Jessica: The following are key risk factors:Modifiable risk factors:Diet and processed foods: A diet high in processed meats, red meat, refined sugars, and low fiber is strongly associated with an increased risk of CRC. Fiber is essential for gut health, and its deficiency has been linked to increased colorectal cancer risk (Dekker et al., 2023).Obesity and sedentary lifestyle: Obesity and physical inactivity contribute to CRC risk by promoting chronic inflammation, insulin resistance, and metabolic disturbances that promote tumor growth (Stoffel & Murphy, 2023).Gut microbiome imbalance: Disruptions in gut microbiota, especially an overgrowth of Fusobacterium nucleatum, have been noted in CRC pathogenesis, potentially causing tumor development and progression (Brennan & Garrett, 2023).Arreaza: As a recap, processed foods, obesity, sedentarism, and gut microbiome. We also have to mention smoking and high alcohol consumption as major risks factors, but the strongest risk factor is a family history of the disease.Non-modifiable risk factors:Genetic predisposition: Although only 20% of early-onset CRC cases are linked to hereditary syndromes such as Lynch syndrome and familial adenomatous polyposis (FAP), individuals with a first-degree relative with CRC are at a significantly higher risk and should undergo earlier and more frequent screening (Stoffel & Murphy, 2023).Arreaza: Also, there is a difference in incidence per gender assigned at birth, which is also not modifiable. The rate in the US was 33% higher in men (41.5 per 100,000) than in women (31.2 per 100,000) during 2015-2019. So, if you are a man, your risk for CRC is slightly higher. Protective factors, according to the ACS, are physical activity (no specification about how much and how often) and dairy consumption (400g/day). Jessica, let's talk about how colon cancer presents in our younger patients.Clinical Presentation and Challenges in DiagnosisJessica: Young-onset CRC is often diagnosed at advanced stages due to delayed recognition of symptoms. Common symptoms include:Rectal bleeding (often mistaken for hemorrhoids)Young individuals may ignore it, believe they do not have time to address it, or lack insurance to cover a comprehensive evaluation.Unexplained weight lossFatigue or weaknessChanges in bowel habits (persistent diarrhea or constipation)This may also be rationalized by dietary habits.Abdominal pain or bloatingIron deficiency anemia.Arreaza: All those symptoms can also be explained by benign conditions, and colorectal cancer can often be present without clear symptoms in its early stages. Jessica: Yes, in young adults, symptoms may be dismissed by healthcare providers as benign conditions such as irritable bowel syndrome (IBS), hemorrhoids, or dietary intolerance, leading to significant diagnostic delays. Arreaza: We must keep a low threshold for ordering a colonoscopy, especially in patients with the risks we mentioned previously. Jessica: We may also be concerned about the risk/benefit of colonoscopy or diagnostic methods in younger adults, given the traditional low likelihood of CRC. Approximately 58% of young CRC patients are diagnosed at stage III or IV, compared to 43% of older adults (American Gastroenterological Association, 2024). Early recognition and prompt evaluation of persistent symptoms are crucial for improving outcomes. Empowering and informing young adults about concerning symptoms is the first step in better recognition and better outcomes for these individuals.Arreaza: This is when the word “follow up” becomes relevant. I recommend you leave the door open for patients to return if their common symptoms worsen or persist. Let's talk about screening. Screening and PreventionJessica: Due to the trend of CRC being identified in younger populations, the U.S. Preventive Services Task Force (USPSTF) lowered the recommended screening age for CRC from 50 to 45 in 2021 (USPSTF, 2021). Off the record, some Gastroenterologists also foresee the USPSTF lowering the age to 40. Arreaza: That is correct, it seems like everyone agrees now that the age to start screening for average-risk adults is 45. It took a while until everyone came to an agreement, but since 2017, the US Multi-Society Task Force had recommended screening at age 45, the American Cancer Society recommended the same age (45) in 2018, and the USPSTF recommended the same age in 2021. This podcast is a reminder that the age of onset has been decreased from 50 to 45, for average-risk patients, according to major medical associations.Jessica: For individuals with additional risk factors, including a family history of CRC or chronic gastrointestinal symptoms, screening starts at age 40 or 10 years before the diagnosis of colon cancer in a first-degree relative. Dr. Arreaza, who has the lowest and the highest rate of screening for CRC in the US? Arreaza: The best rate is in Massachusetts (70%) and the lowest is California (53%). Let's review how to screen:Jessica: Recommended Screening Methods:Colonoscopy: Considered the gold standard for CRC detection and prevention, colonoscopy allows for identifying and removing precancerous polyps.Fecal Immunochemical Test (FIT): A non-invasive stool test that detects hidden blood, recommended annually.Stool DNA Testing (e.g., Cologuard): This test detects genetic mutations associated with CRC and is recommended every three years.Arreaza: Computed tomographic colonography (CTC) is another option, it is less common because it is not covered by all insurance plans, it examines the whole colon, it is quick, with no complications. Conclusion:Colorectal cancer is rapidly emerging as a serious health threat for young adults. The increase in cases over the past three decades highlights the urgent need for increased awareness, early symptom detection, and proactive screening. While healthcare providers must weigh the risk/benefit of testing for CRC in younger adults, patients must also be equipped with knowledge of concerning signs so that they may also advocate for themselves. Early detection remains the most effective tool in preventing and treating CRC, emphasizing the importance of screening and risk factor modification.Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week! _____________________References:American Cancer Society. (2024). Colorectal Cancer Statistics, 2024. Retrieved fromhttps://www.cancer.orgAmerican Gastroenterological Association. (2024). Delays in Diagnosis of Young-Onset Colorectal Cancer: A Systemic Issue. Gastroenterology Today.Brennan, C. A., & Garrett, W. S. (2023). Gut Microbiota and Colorectal Cancer: Advances and Future Directions. Gastroenterology.Dekker, E., et al. (2023). Colorectal Cancer in Adolescents and Young Adults: A Growing Concern. The Lancet Gastroenterology & Hepatology.Siegel, R. L., et al. (2023). Colorectal Cancer Statistics, 2023. CA: A Cancer Journal for Clinicians.Stoffel, E. M., & Murphy, C. C. (2023). Genetic and Environmental Risk Factors in Young-Onset Colorectal Cancer. JAMA Oncology.U.S. Preventive Services Task Force. (2021). Colorectal Cancer Screening Guidelines.Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/.
In this episode, we review the high-yield topic U.S. Preventive Services Task Force Recommendations from the Stats section at Medbullets.com Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets Linkedin: https://www.linkedin.com/company/medbullets
In this episode of Everyday Health Stories, Dr. Kota Reddy and Anna dive into the surprising truth about calcium and vitamin D supplements for bone health. Backed by research from the U.S. Preventive Services Task Force, they discuss why routine supplementation may not significantly reduce fracture risk for healthy, independent adults—and the potential risks, like kidney stones, of overdoing it. Instead, they highlight practical, science-backed tips for maintaining strong bones naturally, including nutrient-rich foods, sunlight exposure, and weight-bearing exercises. Tune in to learn how small, consistent lifestyle changes can make a big difference for your bone health!
The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:1. Insulin Efsitora versus Degludec in Type 2 Diabetes without Previous Insulin Treatment. Discussion by: Guest:Carol Wysham, M.D, Clinical Associate Professor of Medicine University of Washington School of Medicine Section Head of the Department of Diabetes and EndocrinologyRockwood Clinic in Spokane, Washington.2. Cervical Cancer: Screening – Draft statement of the U.S. Preventive Services Task Force. Discussion by:Guest: Amy Clouse Associate Clinical Professor Sidney Kimmell Medical College of Thomas Jefferson University Associate Director - Family Medicine Residency ProgramJefferson Health – Abington3. Chocolate intake and risk of type 2 diabetes: prospective cohort studies. The British Medical Journal 2024. Discussion by: Guest:Elyssa Heisey, DO Resident– Family Medicine Residency Program Jefferson Health – AbingtonMedical Director and Host, Neil Skolnik, MD, is an academic family physician who sees patients and teaches residents and medical students as professor of Family and Community Medicine at the Sidney Kimmel Medical College, Thomas Jefferson University and Associate Director, Family Medicine Residency Program at Abington Jefferson Health in Pennsylvania. Dr. Skolnik graduated from Emory University School of Medicine in Atlanta, Georgia, and did his residency training at Thomas Jefferson University Hospital in Philadelphia, PA. This Podcast Episode does not offer CME/CE Credit. Please visit http://naceonline.com to engage in more live and on demand CME/CE content.
USA TODAY Justice Department Correspondent Bart Jansen looks at the decision by FBI Director Christopher Wray to resign.House Republicans pass a defense policy bill that includes a contentious provision to ban certain types of medical care for transgender children of military service members.USA TODAY Investigative Reporter Chris Quintana discusses how post-grad football lures players with a second shot at glory.The U.S. Preventive Services Task Force recommends self-tests to screen for cervical cancer.Episode Transcript available hereAlso available at art19.com/shows/5-ThingsSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Links/ResourcesU.S. Preventive Services Task Force- https://www.uspreventiveservicestaskforce.org/uspstf/American Cancer Society- https://www.cancer.org/American College of Gastroenterology -https://gi.org/ Feedback or episode ideas email the show at wnlpodcast@copic.comDisclaimer: Information provided in this podcast should not be relied upon for personal, medical, legal, or financial decisions and you should consult an appropriate professional for specific advice that pertains to your situation. Health care providers should exercise their professional judgment in connection with the provision of healthcare services. The information contained in this podcast is not intended to be, nor is it, a substitute for medical diagnosis, treatment, advice, or judgment relative to a patient's specific condition.
The U.S. Preventive Services Task Force and the World Health Organization recommend primary HPV screening, starting at age 25, as an option (some as preferred) for cervical cancer screening. Although primary HPV screening is as effective as cotesting at detecting cervical cancer, primary HPV screening decreases the number of lifetime screenings needed. The primary HPV screening tests approved by the U.S. Food and Drug Administration (FDA) are the Roche Cobas and BD Onclarity tests. HPV results for the Roche and BD tests can be reported as a pooled result. This means the physician receives a result of negative or positive, in which positive indicates that at least one, but possibly more, types of high-risk HPV were identified in the sample. HPV genotyping options differ by manufacturer. Roche Cobas reports HPV 16 and 18 individually and groups 12 other types (i.e., positivity means at least one of the 12 types triggered the positive result). BD Onclarity reports six individual HPV types (16, 18, 31 [the highest risk going immediately to colposcopy], 45, 51, and 52), and combined types (33/58), (35/39/68). Now, as of March/April 2024, the ASCCP has recognized another important and clinically useful HPV and co-test TRIAGE tool, the DUAL STAIN. This pertains only to the ROCHE COBAS HPV test. In this episode, we will review this latest ENDURING GUIDELINES update to the 2019 ASCCP management algorithms (already updated in the ASCCP app).
In this episode, we speak with Dr. Natalie Lui, Assistant Professor of Cardiothoracic Surgery at Stanford University, about lung cancer screening and the importance of early detection. Since lung cancer is often diagnosed in advanced stages, yearly low-dose computed tomography (LDCT) screening is crucial, especially for heavy smokers. We discuss risk factors, screening criteria from the U.S. Preventive Services Task Force, National Comprehensive Cancer Network, and the American Cancer Society, and why screening isn't universal despite its importance. Additionally, we explore current research, recent updates to guidelines, barriers to screening in underserved communities, and the potential of emerging technologies, such as AI, to enhance lung cancer screening in the future. Read Transcript CME Information: https://stanford.cloud-cme.com/medcastepisode92 Claim CE: https://stanford.cloud-cme.com/Form.aspx?FormID=3122
Dr. Lauren Burkard-Mandel discusses the importance of breast cancer screening at age 40 with guest Dr. Debra Monticciolo. They explore the 2023 U.S. Preventive Services Task Force's draft statement advocating for the initiation of biennial mammograms at age 40, down from the previous age of 50. Tune in for an insightful discussion that could impact women's health decisions for years to come! Articles discussed: https://doi.org/10.1093/jbi/wbad103 https://doi.org/10.1002/cncr.33846
The U.S. Preventive Services Task Force updated its screening mammogram recommendations. Having a double mastectomy after being diagnosed with breast cancer in one breast doesn't lower the risk of dying from the disease. Certain types of exercise can reduce the risk of metastatic recurrence and neuropathy caused by chemotherapy. What does all this mean? Breastcancer.org Professional Advisory Board member Dr. Holly Pederson discusses the details of these studies and how they may affect you. Listen to the episode to hear Dr. Pederson discuss these studies: updated U.S. Preventive Services Task Force breast cancer screening recommendations double mastectomy after a cancer diagnosis in one breast reduces the risk of cancer in the other breast, but doesn't decrease the risk of dying from breast cancer neuromuscular training reduces chemotherapy-induced peripheral neuropathy exercise reduces the risk of metastatic recurrence of hormone receptor-negative breast cancer hormonal therapy doesn't increase dementia risk Scroll down to below the “About the guest” information to read a transcript of this podcast.
The U.S. Preventive Services Task Force has updated its recommendations for breast cancer screening once again. The recommendations now stipulate that women and people assigned female at birth should begin getting mammograms at age 40, and continue every other year until age 74. The previous guidelines recommended beginning screening at age 50. These guidelines carry a lot of weight because they determine if mammography will be considered preventive care by health insurance and therefore covered at no cost to the patient.Why have the guidelines changed? And how are these decisions made in the first place? To answer those questions and more Ira Flatow talks with Dr. Janie Lee, director of breast imaging at the Fred Hutchinson Cancer Center and professor of radiology at the University of Washington School of Medicine.Transcript for this segment will be available the week after the show airs on sciencefriday.com. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
New guidance from the U.S. Preventive Services Task Force recommends women should get a mammogram every other year starting at age 40 and continuing until age 74. With so much at stake, it's important to stay in the know. Soundside spoke with Dr. Janie Lee, professor of Radiology at the University of Washington and the director of breast imaging services for the UW and Fred Hutch Cancer Center, to learn more.
A key scientific panel updated its recommendations on breast cancer screenings and the changes could potentially save thousands of lives. The U.S. Preventive Services Task Force now recommends that all women start getting biennial mammograms at age 40. The previous guidelines started at age 50. Ali Rogin discussed more with Dr. Wanda Nicholson. PBS NewsHour is supported by - https://www.pbs.org/newshour/about/funders
A new abortion law goes into effect in Florida on Wednesday. It will sharply restrict the procedure after six weeks. Florida's new law includes exceptions for rape, incest, fetal abnormalities and the life of the mother.New York City Mayor Eric Adams talks about the protests at Columbia University after pro-Palestinian demonstrators were removed by police from an academic building on campus.The U.S. Preventive Services Task Force is recommending women get a mammogram every other year, starting at age 40. Dr. Celine Gounder, a CBS News medical contributor and editor-at-large for public health at KFF Health News, explains.New Yorkers got a front-row seat to a one-of-a-kind show by one of racing's biggest stars yesterday. Seven-time Formula One World Champion Lewis Hamilton sped down Fifth Avenue, even stopping to do donuts right outside the iconic Empire State Building. The stunt was planned to promote a partnership with WhatsApp and Hamilton's Mercedes F1 team, and their growth here in the U.S. Gayle King sat down exclusively with the global superstar right after the stunt.Author Emily Oster, known for her influential book "Expecting Better," introduces her fourth book, "The Unexpected: Navigating Pregnancy During and After Complications."First on CBS Mornings, Dame Judi Dench shares memories from her 70-year-career playing Shakespearean roles as she discusses her new book, "Shakespeare: The Man Who Pays the Rent" with CBS News' Anthony Mason.In our "Changing the Game" series, we celebrate Asian American and Pacific Islander Heritage Month by spotlighting Lulu Cheng and Lacey Benard. After identifying a gap in Chinese learning resources for children, they founded Bitty Bao in 2020. Their company has since produced 15 bilingual board books and innovative educational toys like a Hot Pot kit.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
May 1, 2024 ~ As Women's Health Month, the U.S. Preventive Services Task Force announced mammograms should begin at 40. Stephanie Vandertill, Oncology Nurse Navigator at DMC Huron-Valley- Sinai Grace Hospital in Commerce Township, joins Kevin and Marie to explain why this is.
What is a preventive screening? Does USPSTF screen for mental health? What are the best preventive screenings? Plus, why an anxiety screening for adults is now recommended. Our guest is Michael Barry, MD, chair of the U.S. Preventive Services Task Force. American Medical Association CXO Todd Unger hosts.
In this episode of the Black Health 365 podcast, Jackie and Britt are joined by Dr. Esa Davis, a U.S. Preventive Services Task Force member. Dr. Davis is a professor of medicine and family and community medicine and holds the positions of Associate Vice President for community health and senior dean of population and community medicine at the University of Maryland School of Medicine. During the podcast, Dr. Davis explains the importance of the US Preventive Services Task Force for hypertensive disorders of pregnancy. She shares how screenings can help diagnose hypertensive disorders like preeclampsia and hypertension. The nationwide initiative can assist expectant mothers and decrease the black maternal death rate in our community. Jackie and Britt hope this information will inspire our community to learn about the U.S. Preventative Services Task Force recommendations and seek medical attention sooner during pregnancy. Dr. Esa Davis is a Task Force member and a professor of medicine and family and community medicine, the associate vice president for community health, and the senior associate dean of population and community medicine at the University of Maryland School of Medicine. She is the lead health equity strategist for the University of Maryland Institute for Health Computing. Dr. Davis is also the director of the Transforming Biomedical Research and Academic Faculty Through Leadership Opportunities, Training, and Mentorship (TRANSFORM) program.See omnystudio.com/listener for privacy information.
Steven Woloshin is a professor of medicine and the director of the Center for Medicine and the Media at the Dartmouth Institute and a member of the Dartmouth Cancer Center. Stephen Morrissey, the interviewer, is the Executive Managing Editor of the Journal. S. Woloshin and Others. The New USPSTF Mammography Recommendations — A Dissenting View. N Engl J Med 2023;389:1061-1064.
On May 9 the U.S. Preventive Services Task Force issued new mammogram guidelines. Starting at age 40, women are urged to get screened every other year. Dr. Date will explain the new guidelines and how they were developed.
Colon cancer is the most common type of gastrointestinal cancer and rates of diagnosis have nearly doubled in people under the age of 55. Because of this rise, in 2021 the U.S. Preventive Services Task Force issued the recommendation that the screening age for colonoscopies be lowered to 45 for those at an average risk for developing colorectal cancer. Today, our dietitians will add some nutritional information and lifestyle habits to the cancer conversation to help with the stress and questions that might come up with a diagnosis or a goal for prevention.
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-331 Overview: Current recommendations for when to start breast cancer screening do not consider race or ethnicity, which may be a source of racial disparity in breast cancer outcomes. In this installment, we take a closer look at these recommendations and how you can incorporate them into individualized patient care. Episode resource links: Chen T, Kharazmi E, Fallah M. Race and Ethnicity-Adjusted Age Recommendation for Initiating Breast Cancer Screening. JAMA Netw Open. 2023;6(4):e238893. Published 2023 Apr 3. Siu AL; U.S. Preventive Services Task Force. Screening for Breast Cancer: U.S. Preventive Services Task Force Recommendation Statement [published correction appears in Ann Intern Med. 2016 Mar 15;164(6):448]. Ann Intern Med. 2016;164(4):279-296 Oeffinger KC, Fontham ET, Etzioni R, et al. Breast Cancer Screening for Women at Average Risk: 2015 Guideline Update From the American Cancer Society [published correction appears in JAMA. 2016 Apr 5;315(13):1406]. JAMA. 2015;314(15):1599-1614. Draft Update of USPSTF Screening for Breast Cancer: https://www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/breast-cancer-screening-adults Guest: Alan M. Ehrlich MD, FAAFP Music Credit: Richard Onorato
Credits: 0.25 AMA PRA Category 1 Credit™ CME/CE Information and Claim Credit: https://www.pri-med.com/online-education/podcast/frankly-speaking-cme-331 Overview: Current recommendations for when to start breast cancer screening do not consider race or ethnicity, which may be a source of racial disparity in breast cancer outcomes. In this installment, we take a closer look at these recommendations and how you can incorporate them into individualized patient care. Episode resource links: Chen T, Kharazmi E, Fallah M. Race and Ethnicity-Adjusted Age Recommendation for Initiating Breast Cancer Screening. JAMA Netw Open. 2023;6(4):e238893. Published 2023 Apr 3. Siu AL; U.S. Preventive Services Task Force. Screening for Breast Cancer: U.S. Preventive Services Task Force Recommendation Statement [published correction appears in Ann Intern Med. 2016 Mar 15;164(6):448]. Ann Intern Med. 2016;164(4):279-296 Oeffinger KC, Fontham ET, Etzioni R, et al. Breast Cancer Screening for Women at Average Risk: 2015 Guideline Update From the American Cancer Society [published correction appears in JAMA. 2016 Apr 5;315(13):1406]. JAMA. 2015;314(15):1599-1614. Draft Update of USPSTF Screening for Breast Cancer: https://www.uspreventiveservicestaskforce.org/uspstf/draft-recommendation/breast-cancer-screening-adults Guest: Alan M. Ehrlich MD, FAAFP Music Credit: Richard Onorato
Americans are racking up credit card debt at unprecedented rates, approaching $1 trillion, surpassing the pre-pandemic high. CBS News business analyst Jill Schlesinger joins "CBS Mornings" to explain what's driving the increase, and what you should do if you're struggling with credit card debt.The U.S. Preventive Services Task Force issued updated draft breast cancer screening guidelines recommending all women at average risk should start getting screened for breast cancer every other year starting at age 40, a decade earlier than previous guidelines. CBS News medical contributor and editor-at-large for Public Health at KFF, Dr. Celine Gounder, joins "CBS Mornings" to discuss.A Utah woman who wrote a children's book to help her three sons process their father's sudden death has been arrested for his murder. Prosecutors said she poisoned him with a lethal dose of fentanyl.For more than half a century, student "quiz bowlers" have faced the pressure of the buzzer and showed off their knowledge in front of cameras. But as CBS News' Scott MacFarlane shows us, times have changed and now it's the quiz shows themselves facing pressure to survive."CBS Mornings" co-host Gayle King sits down with Lady A's Charles Kelley and his wife Cassie Kelley in an exclusive interview about his path to sobriety.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
The draft recommendations from the U.S. Preventive Services Task Force state that women who are ages 40 to 74 should have screening mammograms every two years. Sandford Health's Dr. Andrea Kaster provides her insight as to why this change dropped from 50 years old to 40.See omnystudio.com/listener for privacy information.
New guidelines say women should begin getting regular mammograms every two years starting at age 40 if they are at average risk of breast cancer. That's a significant change from previous guidance by the U.S. Preventive Services Task Force that said women could start routine mammograms at 50. Stephanie Sy reports. PBS NewsHour is supported by - https://www.pbs.org/newshour/about/funders
Women should be receiving regular mammograms starting at age 40, according to new draft guidance from the U.S. Preventive Services Task Force. Americans have conflicting views on anti-trans policies being pushed in Republican states, says a new Washington Post-KFF poll. KCRW looks at the nuances. The killer in the mass shooting at a Dallas-area mall was Latino, and according to reports, may have held white supremacist beliefs. Is that common? More than a dozen universities have closed in Japan due to its declining population. Could the U.S. be in store for the same fate, as college enrollment slips here? In Netflix's “Beef,” two strangers get into a dispute in a parking lot, and the random encounter devolves into catfishing, kidnapping, and more.
New guidelines say women should begin getting regular mammograms every two years starting at age 40 if they are at average risk of breast cancer. That's a significant change from previous guidance by the U.S. Preventive Services Task Force that said women could start routine mammograms at 50. Stephanie Sy reports. PBS NewsHour is supported by - https://www.pbs.org/newshour/about/funders
Dr. Jeffrey Kopin, Chief Medical Officer for Northwestern Medicine Lake Forest Hospital, joins John Williams to talk about the WHO declaring an end to COVID-19 as a public health emergency, the Federal COVID-19 Public Health Emergency Declaration ending on Thursday, if this is a bad season for allergies, and the U.S. Preventive Services Task Force recommending that […]
Dr. Jeffrey Kopin, Chief Medical Officer for Northwestern Medicine Lake Forest Hospital, joins John Williams to talk about the WHO declaring an end to COVID-19 as a public health emergency, the Federal COVID-19 Public Health Emergency Declaration ending on Thursday, if this is a bad season for allergies, and the U.S. Preventive Services Task Force recommending that […]
Dr. Jeffrey Kopin, Chief Medical Officer for Northwestern Medicine Lake Forest Hospital, joins John Williams to talk about the WHO declaring an end to COVID-19 as a public health emergency, the Federal COVID-19 Public Health Emergency Declaration ending on Thursday, if this is a bad season for allergies, and the U.S. Preventive Services Task Force recommending that […]
Amidst the battle of the mental health crisis, major depressive disorder stands out as an all-too-common reality for many children and adolescents, but the forces of science and medicine can stand against this foe. Dr. Christopher Drescher, a clinical child psychologist, joins pediatric resident Dr. Daniel Allen and medical student Vuk Lacmanovic to remove the cape from this increasingly common condition and discuss its symptoms, diagnosis, and treatment. Specifically, they will: Define major depressive disorder (MDD) and recognize the common symptoms in both children and adolescents. Formulate a differential diagnosis for patients presenting with depressive symptoms. Recognize validated screening tools for depression in both children and adolescents. Review cognitive behavioral therapy and pharmacotherapy as treatment options. Review appropriate referral to a mental health specialist. Free CME Credit (requires sign-in): https://mcg.cloud-cme.com/course/courseoverview?P=0&EID=12493 References: Bhatia SK, Bhatia SC. Childhood and adolescent depression. Am Fam Physician. 2007 Jan 1;75(1):73-80. PMID: 17225707. Brent DA, Maalouf F. Depressive Disorders (in Childhood and Adolescence). In: Ebert MH, Leckman JF, Petrakis IL. eds. Current Diagnosis & Treatment: Psychiatry, 3e. McGraw-Hill; Accessed November 17, 2020. https://accessmedicine.mhmedical.com/content.aspx?bookid=2509§ionid=200807606 Clark MS, Jansen KL, Cloy JA. Treatment of childhood and adolescent depression. Am Fam Physician. 2012 Sep 1;86(5):442-8. PMID: 22963063. Fendrich M, Weissman MM, Warner V. Screening for depressive disorder in children and adolescents: validating the Center for Epidemiologic Studies Depression Scale for Children. Am J Epidemiol. 1990 Mar;131(3):538-51. doi: 10.1093/oxfordjournals.aje.a115529. PMID: 2301363. (PDF of CES-DC here) Forman-Hoffman V, McClure E, McKeeman J, Wood CT, Middleton JC, Skinner AC, Perrin EM, Viswanathan M. Screening for Major Depressive Disorder in Children and Adolescents: A Systematic Review for the U.S. Preventive Services Task Force. Ann Intern Med. 2016 Mar 1;164(5):342-9. doi: 10.7326/M15-2259. Epub 2016 Feb 9. PMID: 26857836. Hathaway EE, Walkup JT, Strawn JR. Antidepressant Treatment Duration in Pediatric Depressive and Anxiety Disorders: How Long is Long Enough? Curr Probl Pediatr Adolesc Health Care. 2018 Feb;48(2):31-39. doi: 10.1016/j.cppeds.2017.12.002. Epub 2018 Jan 12. PMID: 29337001; PMCID: PMC5828899. March JS, Silva S, Petrycki S, Curry J, Wells K, Fairbank J, Burns B, Domino M, McNulty S, Vitiello B, Severe J. The Treatment for Adolescents With Depression Study (TADS): long-term effectiveness and safety outcomes. Arch Gen Psychiatry. 2007 Oct;64(10):1132-43. doi: 10.1001/archpsyc.64.10.1132. Erratum in: Arch Gen Psychiatry. 2008 Jan;65(1):101. PMID: 17909125. Meister R, Abbas M, Antel J, Peters T, Pan Y, Bingel U, Nestoriuc Y, Hebebrand J. Placebo response rates and potential modifiers in double-blind randomized controlled trials of second and newer generation antidepressants for major depressive disorder in children and adolescents: a systematic review and meta-regression analysis. Eur Child Adolesc Psychiatry. 2020 Mar;29(3):253-273. doi: 10.1007/s00787-018-1244-7. Epub 2018 Dec 8. PMID: 30535589; PMCID: PMC7056684. Rachel A. Zuckerbrot, Amy Cheung, Peter S. Jensen, Ruth E.K. Stein, Danielle Laraque and GLAD-PC STEERING GROUP. Guidelines for Adolescent Depression in Primary Care (GLAD-PC): Part I. Practice Preparation, Identification, Assessment, and Initial Management. Pediatrics March 2018, 141 (3) e20174081; DOI: https://doi.org/10.1542/peds.2017-4081 Scott K, Lewis CC, Marti CN. Trajectories of Symptom Change in the Treatment for Adolescents With Depression Study. J Am Acad Child Adolesc Psychiatry. 2019 Mar;58(3):319-328. doi: 10.1016/j.jaac.2018.07.908. Epub 2019 Jan 8. PMID: 30768414; PMCID: PMC6557284. Sharma T, Guski LS, Freund N, Gøtzsche PC. Suicidality and aggression during antidepressant treatment: systematic review and meta-analyses based on clinical study reports. BMJ. 2016 Jan 27;352:i65. doi: 10.1136/bmj.i65. PMID: 26819231; PMCID: PMC4729837. Siu AL; US Preventive Services Task Force. Screening for Depression in Children and Adolescents: US Preventive Services Task Force Recommendation Statement. Pediatrics. 2016 Mar;137(3):e20154467. doi: 10.1542/peds.2015-4467. Epub 2016 Feb 8. PMID: 26908686. Weersing VR, Brent DA, Rozenman MS, Gonzalez A, Jeffreys M, Dickerson JF, Lynch FL, Porta G, Iyengar S. Brief Behavioral Therapy for Pediatric Anxiety and Depression in Primary Care: A Randomized Clinical Trial. JAMA Psychiatry. 2017 Jun 1;74(6):571-578. doi: 10.1001/jamapsychiatry.2017.0429. PMID: 28423145; PMCID: PMC5539834. Weersing VR, Shamseddeen W, Garber J, Hollon SD, Clarke GN, Beardslee WR, Gladstone TR, Lynch FL, Porta G, Iyengar S, Brent DA. Prevention of Depression in At-Risk Adolescents: Predictors and Moderators of Acute Effects. J Am Acad Child Adolesc Psychiatry. 2016 Mar;55(3):219-26. doi: 10.1016/j.jaac.2015.12.015. Epub 2016 Jan 18. PMID: 26903255; PMCID: PMC4783159. Xu Y, Bai SJ, Lan XH, Qin B, Huang T, Xie P. Randomized controlled trials of serotonin-norepinephrine reuptake inhibitor in treating major depressive disorder in children and adolescents: a meta-analysis of efficacy and acceptability. Braz J Med Biol Res. 2016 May 24;49(6):e4806. doi: 10.1590/1414-431X20164806. PMID: 27240293; PMCID: PMC4897997. Zhou X, Cipriani A, Zhang Y, Cuijpers P, Hetrick SE, Weisz JR, Pu J, Giovane CD, Furukawa TA, Barth J, Coghill D, Leucht S, Yang L, Ravindran AV, Xie P. Comparative efficacy and acceptability of antidepressants, psychological interventions, and their combination for depressive disorder in children and adolescents: protocol for a network meta-analysis. BMJ Open. 2017 Aug 11;7(8):e016608. doi: 10.1136/bmjopen-2017-016608. PMID: 28801423; PMCID: PMC5629731. Zhou X, Teng T, Zhang Y, Del Giovane C, Furukawa TA, Weisz JR, Li X, Cuijpers P, Coghill D, Xiang Y, Hetrick SE, Leucht S, Qin M, Barth J, Ravindran AV, Yang L, Curry J, Fan L, Silva SG, Cipriani A, Xie P. Comparative efficacy and acceptability of antidepressants, psychotherapies, and their combination for acute treatment of children and adolescents with depressive disorder: a systematic review and network meta-analysis. Lancet Psychiatry. 2020 Jul;7(7):581-601. doi: 10.1016/S2215-0366(20)30137-1. PMID: 32563306; PMCID: PMC7303954.
Although there are many effective treatments for depression, rates of depression are not going down. The National Academies of Science, Engineering, and Medicine have recommended that we implement currently known effective preventive interventions for depression to reduce the number of new cases. This talk will present a personal 50-year path committed to preventing mental disorders and influencing major health-science institutions to implement practices to prevent depression; examples of the types of prevention interventions currently available, with illustrations of the methods that have been found most useful (so that lay persons in a broad audience can envision what can be done to prevent clinical depression); a focus on preventing depression during pregnancy and postpartum, the benefit to the mother and to the baby, and how the U.S. Preventive Services Task Force has recommended that pregnant persons at risk for depression be provided with preventive interventions that have been shown to be effective—and how doing this can have lifetime impact on the health of the babies; how digital tools can be harnessed to reach as many people as possible with these interventions, making it possible to “think globally, act locally and share globally.” Given that we can now prevent half the cases of clinical depression, what needs to be done to prevent the other half? Bottom Line: The health sciences have made major progress in terms of learning how to prevent depression. We now need to act by putting these methods into practice and reduce much of the suffering due to depression. About the Speaker Ricardo F. Muñoz, Ph.D., emigrated from Perú at age 10. He obtained his B.A. from Stanford in 1972 and his Ph.D. in clinical psychology at the University of Oregon in 1977. He was named distinguished professor of clinical psychology at Palo Alto University in 2012, where he is the founding director of i4Health, the Institute for International Internet Interventions for Health (i4health.paloaltou.edu). He is professor of psychology, emeritus, at the School of Medicine of the University of California, San Francisco, based at San Francisco General Hospital, where he taught and did clinical work and research for 35 years, and adjunct clinical professor at Stanford University. Muñoz has served on three U.S. National Academies of Science, Engineering, and Medicine Consensus Committees on prevention of mental disorders. He is a fellow of the American Psychological Association, the Association for Psychological Science, and of the American Association for the Advancement of Science “for distinguished contributions towards the prevention of major depression and the development of Internet interventions to improve mental health worldwide.” SPEAKERS Ricardo F. Muñoz Ph.D., Founding Director, i4Health; Professor of Psychology, Emeritus, School of Medicine, University of California San Francisco Patrick O'Reilly Ph.D., Chair, Psychology Member-led Forum, The Commonwealth Club of California—Moderator In response to the COVID-19 pandemic, we are currently hosting all of our live programming via YouTube live stream. This program was recorded via video conference on December 8th, 2022 by the Commonwealth Club of California. Learn more about your ad choices. Visit megaphone.fm/adchoices
VIDEOS: Video Emerges Where Fauci and Others Planned for a “Universal mRNA Flu Vaccine” Which Became the “COVID-19 mRNA Vaccine” Because People were not Afraid Enough of the Flu Virus (1:51) You're Not Going To Believe This! | Mark Steyn & Eva Vlaardingerbroek (3:03) Neil Oliver – ‘…it's a toxic hell…' (START @ 9:00) Gravitas: Who helped Taliban repair the abandoned American aircraft? (7:25) Healthy plant-based diets associated with lower colorectal cancer risk in men Kyung Hee University, South Korea, November 28, 2022 Eating a plant-based diet rich in healthy plant foods—such as whole grains, vegetables, and legumes—and low in unhealthy plant foods—including refined grains, fruit juices, and added sugars—is associated with a lower risk of colorectal cancer in men. The findings are published in the open access journal BMC Medicine.Jihye Kim, the corresponding author, said, “Colorectal cancer is the third-most common cancer worldwide, and the risk of developing colorectal cancer over a lifetime is one in 23 for men and one in 25 for women. Although previous research has suggested that plant-based diets may play a role in preventing colorectal cancer, the impact of plant foods' nutritional quality on this association has been unclear. Our findings suggest that eating a healthy plant-based diet is associated with a reduced risk of colorectal cancer.” Researchers from Kyung Hee University, South Korea found that among a population of 79,952 American men, those who ate the highest average daily amounts of healthy plant-based foods had a 22% lower risk of colorectal cancer, compared to those who ate the lowest amounts of healthy plant foods. However, the authors did not identify any significant associations between the nutritional quality of plant-based diets and colorectal cancer risk among a population of 93,475 American women. Jihye Kim said, “We speculate that the antioxidants found in foods such as fruits, vegetables, and whole grains could contribute to lowering colorectal cancer risk by suppressing chronic inflammation, which can lead to cancer. As men tend to have a higher risk of colorectal cancer than women, we propose that this could help explain why eating greater amounts of healthy plant-based foods was associated with reduced colorectal cancer risk in men but not women.” The authors found that the association between the nutritional quality of plant-based diets and colorectal cancer risk among men varied by race and ethnicity. Among Japanese American men, colorectal cancer risk was 20% lower for those who ate the highest amount of healthy plant foods per day than for those who ate the lowest amount. Among white men, those who ate the highest amount of highest amount of healthy plant foods had a 24% lower colorectal cancer risk than those who ate the lowest amount. The authors did not identify any significant associations between plant-based diets and colorectal cancer risk among African American, Latino or Native Hawaiian men. (next) Green Mediterranean diet reduces twice as much visceral fat as traditional Mediterranean diet Ben-Gurion University of the Negev (Israel), November 28, 2022 Following the green Mediterranean diet significantly reduces visceral adipose tissue, a type of fat around internal organs that is much more dangerous than the extra “tire” around your waist. Recently, researchers compared the green Mediterranean diet to the traditional Mediterranean diet and a non-Mediterranean healthy diet in a large-scale clinical interventional trial—the DIRECT PLUS. Subsequent analysis found that the green Mediterranean diet reduced visceral fat by 14%, the Mediterranean diet by 7% and the non-Mediterranean healthy diet by 4.5%. The study was published in BMC Medicine. Reducing visceral fat is considered the true goal of weight loss, as it is a more important indicator than a person's weight or the circumference of their waist. Visceral fat aggregates over time between organs, and produces hormones and poisons linked to heart disease, diabetes, dementia and premature death. The DIRECT-PLUS trial research team was the first to introduce the concept of the green Mediterranean diet. This modified Mediterranean diet is further enriched with dietary polyphenols and is lower in red/processed meat than the traditional Mediterranean diet. On top of a daily intake of walnuts (28 grams), the participants consumed 3-4 cups of green tea/day and 100 grams (frozen cubes) of duckweed green shake/day. The aquatic green plant duckweed is high in bioavailable protein, iron, B12, vitamins, minerals, and polyphenols and substituted meat intake. The team has shown in previous studies that the green Mediterranean diet has a variety of salutary effects ranging from the microbiome to age-related degenerative diseases. A group of 294 participants took part in the 18-month long trial. “A 14% reduction in visceral fat is a dramatic achievement for making simple changes to your diet and lifestyle. Weight loss is an important goal only if it is accompanied by impressive results in reducing adipose tissue,” notes Dr. Hila Zelicha. (next) Are older women being over-screened for cervical cancer? University of Illinois at Chicago, November 28, 2022 A new study published in JAMA Internal Medicine suggests that women over the age of 65 may be undergoing unnecessary cervical cancer screenings and that more public health data is needed on the utilization of cervical cancer screening-associated services among older women to prevent potential harm and unnecessary costs. The study, which is authored by experts from the University of Illinois Chicago, the University of California San Francisco and the U.S. Centers for Disease Control and Prevention, looked at Medicare claims data from 1999 to 2019 for fee-for-service care for women over the age of 65. The analysis showed that in 2019 more than 1.3 million women received cervical cancer screening-associated services, such as a Pap test, colposcopy, and other cervical procedures after age 65. While these services cost more than $83 million, the researchers concluded they were of “unclear clinical appropriateness.” “Cervical cancer screening and other preventive services are among our most important tools for keeping people healthy throughout life, but screenings should also follow evidence-based guidelines to prevent overspending, potential complications and patient discomfort,” said study co-author Dr. Hunter Holt, assistant professor of family and community medicine at the University of Illinois Chicago. According to recommendations and guidelines from the U.S. Preventive Services Task Force, the American Cancer Society and the American College of Obstetrics and Gynecology, women considered to be of average risk can stop undergoing routine cervical cancer screening once they reach the age of 65 if they have had adequate prior screening. “The decision to end cervical cancer screening for women after age 65 requires review of past screening results and related medical history. This process can promote cervical cancer prevention and prevent harms and costs from unnecessary tests and procedures,” said Jin Qin, study co-author and epidemiologist in CDC's Division of Cancer Prevention and Control. The researchers say that the high rates of screening among older women is potentially concerning. “It could be that women are getting screened when they do not need to, or that these women are considered to be at higher-than-average risk, for example, because they have not been adequately screened prior to 65. We do not want to see either of these things and unfortunately, there is not enough public health data to shed light on the causes,” said Holt, who is also affiliated with the University of Illinois Cancer Center at UIC. (next) Chemotherapy could increase disease susceptibility in future generations Washington State University, November 28, 2022 A common chemotherapy drug could carry a toxic inheritance for children and grandchildren of adolescent cancer survivors, Washington State University-led research indicates. The study, published online in iScience, found that male rats who received the drug ifosfamide during adolescence had offspring and grand-offspring with increased incidence of disease. While other research has shown that cancer treatments can increase patients' chance of developing disease later in life, this is one of the first-known studies showing that susceptibility can be passed down to a third generation of unexposed offspring. “The findings suggest that if a patient receives chemotherapy, and then later has children, that their grandchildren, and even great-grandchildren, may have an increased disease susceptibility due to their ancestors' chemotherapy exposure,” said Michael Skinner, a WSU biologist and corresponding author on the study. Given this study's implications, the researchers recommend that cancer patients who plan to have children later take precautions, such as using cryopreservation to freeze sperm or ova before having chemotherapy. In the study, researchers exposed a set of young male rats to ifosfamide over three days, mimicking a course of treatment an adolescent human cancer patient might receive. Those rats were later bred with female rats who had not been exposed to the drug. The resulting offspring were bred again with another set of unexposed rats. The first-generation offspring had some exposure to the chemotherapy drug since their fathers' sperm was exposed, but researchers found greater incidence of disease in not only the first- but also the second-generation, who had no direct exposure to the drug. While there were some differences by generation and sex, the associated problems included greater incidence of kidney and testis diseases as well as delayed onset of puberty and abnormally low anxiety, indicating a lowered ability to assess risk. The results of the researchers' analysis showed epigenetic changes in two generations linked to the chemotherapy exposure of the originally exposed rats. The fact that these changes could be seen in the grand-offspring, who had no direct exposure to the chemotherapy drug, indicates that the negative effects were passed down through epigenetic inheritance. (next) Saffron can fight liver cancer, reveal UAE researchers United Arab Emirates University, November 20, 2022 It may be an expensive spice but you cannot put a label or price on health, said Professor Amr Amin who has researched a breakthrough in the properties of saffron in fighting liver cancer. Professor Amin from Cellular & Molecular Biology at United Arab Emirates University said that researchers have investigated and found saffron to have anti-liver cancer properties. “Safranal, a major biomolecule of the golden spice saffron arrests and stops the cancer cell division at two different stages,” he said. The UAE researchers have been working on this project since 2011 when they first published the research in the Hepatology Journal. The study suggests a novel mechanism of anti-proliferative activity of safranal against human liver cancer cells. “This molecule could serve as a novel and/or adjuvant drug to treat liver cancer,” said Dr Amin. The findings are now also published in a Nature journal Scientific Reports. “The ingredient works in two ways; it stops cell division and promotes cell death,” he explained. Prof Amin and colleagues concluded that safranal exerts its anticancer effect in HepG2 cells by inhibiting DNA repair, resulting in increased DNA damage. (next) Japanese researchers say that ultrasound therapy can be used to treat patients with dementia Tohoku University (Japan), November 20, 2022 A new therapy based on ultrasound waves might be able to improve the cognitive powers of patients suffering from Alzheimer's disease and other forms of dementia. According to an article on the Tohoku University news page, the approach improved the condition of mice with symptoms similar to human dementia. In their experiment, the Tohoku University research team sent low-intensity pulsed ultrasound (LIPUS) waves through the brain of the mice. They found that the waves improved the creation of blood vessels and the rate of regeneration of nerve cells. Furthermore, the treatment did not cause any notable side effects on the mice. The results led the researchers to believe that they can replicate their experimental success in actual human patients one day. “The LIPUS therapy is a non-invasive physiotherapy that could apply to high-risk elderly patients without the need for surgery or anaesthesia, and could be used repeatedly,” explained TU researcher Hiroaki Shimokawa. The Tohoku researchers applied LIPUS therapy to the whole brain of mice with symptoms that resemble those of Alzheimer's disease or vascular dementia. They did this three times a day, with each session lasting for 20 minutes. The mice that simulated vascular dementia underwent surgery that reduced the amount of blood that reached the brain. These animals underwent LIPUS treatment on the first, third, and fifth days after that surgery. Meanwhile, the mice that modeled Alzheimer's disease got 11 LIPUS treatments over a three-month-long trial period. By the end of the experiment, the researchers found that LIPUS activated genes involved with the cells that made up the inner lining of blood vessels. Furthermore, an enzyme that promoted blood vessel formation displayed increased activity, as did a protein which helped nerve cells grow. Based on their findings, whole-brain LIPUS therapy can help alleviate the symptoms of certain forms of dementia by encouraging the development of cells that are normally affected by the condition. The technique is currently undergoing initial clinical trials that will determine its efficacy and safety.
This week the U.S. Preventive Services Task Force announced recommendations that doctors screen all patients under 65 for anxiety. Since the beginning of the pandemic, we've heard about sharp increases in the number of people suffering from mental health problems. With a health care system already overburdened and seemingly unable to deal with the rise in mental health issues, America is facing what is being called a mental health crisis.But are we losing sight of another crisis - the issues causing increased anxiety and depression in Americans?Host Michel Martin speaks with Dr. Danielle Carr about her recent essay in the New York Times, Mental Health Is Political.
This week we chat with Dr. Tracy Gapin, board certified by the American Board of Urology, a Fellow of the American College of Surgeons, and author of the bestselling book Male 2.0: Cracking the Code to Limitless Health and Vitality. Dr. Gapin shares with us his methods of offering a personalized path to help men maximize sexual health, testosterone levels, and prostate health. Text HEALTH to 26786 for a free digital copy of Male 2.0 and a discovery call with Dr. Gapin. On What The Health?!: Check your heart, check your reflexes, check your mental health. Way to go, U.S. Preventive Services Task Force! Use code FUNC for 20% off at Wildhealth.com! Use code FUNC for $500 off tuition at Functional Medicine Coaching Academy. Follow Dr. Tracy Gapin on IG @drtracygapin Follow us on IG @whatthefunc
The Teton County coroner announced Gabby Petito's cause of death was strangulation and the manner of death was homicide. Petito was reported missing on September 11. She had been traveling on a road trip with her fiancé, Brian Laundrie, who returned to Florida without her and hasn't been in over a month. Dr. Brent Blue is the Teton County coroner. He tells Anderson Cooper “there is no evidence that this was done by any kind of animal” and “we believe this is strangling by human being.” The U.S. Preventive Services Task Force is considering making changes to its guidance on taking a daily aspirin to prevent heart disease and stroke. CNN's Chief Medical Correspondent Dr. Sanjay Gupta joins AC360 to explain the possible changes and says “they're not saying you should stop” taking an aspirin if you've already been taking one. Airdate: October 12, 2021 Guests: Dr. Brent Blue Dr. Sanjay Gupta To learn more about how CNN protects listener privacy, visit cnn.com/privacy