Podcasts about Neurogenetics

When someone we know or love starts to develop psychological issues, we don't often associate it with a form of dementia. However, this trait is one of the most common signs of frontotemporal dementia (FTD) — the most common neurodegenerative disease in people under the age of 65. In his new book, Mysteries of the Social Brain: Understanding Human Behavior Through Science, Dr. Bruce Miller highlights his experiences observing people with FTD and what they have taught him about what he calls the "social brain."Dr. Bruce Miller has been observing people with FTD for decades in the Memory and Aging Center at the University of San Francisco, where he is also Professor of Neurology and the Founding Director of the Global Brain Health Institute. He shares key insights on how to keep our "social brain" healthy and how it can even unlock our creative potential.

Send us a textDr. Catharine Young, Ph.D. recently served as Assistant Director of Cancer Moonshot Policy and International Engagement at the White House Office of Science and Technology Policy ( https://www.whitehouse.gov/ostp/ ) where she served at OSTP to advance the Cancer Moonshot ( https://www.cancer.gov/research/key-initiatives/moonshot-cancer-initiative ), with a mission to decrease the number of cancer deaths by 50% over the next 25 years. Dr. Young's varied career has spanned a variety of sectors including academia, non-profit, biotech, and foreign government, all with a focus on advancing science. Dr. Young previously served as Executive Director of the SHEPHERD Foundation, where she championed rare cancer research and drove critical policy changes. Her work has also included fostering interdisciplinary collaborations and advancing the use of AI, data sharing, and clinical trial reform to accelerate cancer breakthroughs.Dr. Young's leadership in diplomacy and innovation includes roles such as Senior Director of Science Policy at the Biden Cancer Initiative and Senior Science and Innovation Policy Advisor at the British Embassy, where she facilitated international agreements to enhance research collaborations. A Presidential Leadership Scholar and TED Fellow, Dr. Young holds a Ph.D. in Biomedical Sciences and completed her post-doctorate work in Biomedical Engineering at Cornell University and is recognized for her ability to bridge science, policy, and advocacy to build sustainable, impactful health ecosystems.#CatharineYoung #OSTP #WhiteHouseOfficeOfScienceAndTechnologyPolicy #CancerMoonshot #SHEPHERDFoundation #BidenCancerInitiative #DepartmentOfDefense #BritishEmbassy #Neurogenetics #AntimicrobialResistance #GlobalHealthSecurityAgenda #OneHealth #RareCancers #ChildhoodCancer #RareDisease #ForeignAndCommonwealthOffice #BiologicalThreats #MitigationStrategies #RiskMitigation #ProgressPotentialAndPossibilities #IraPastor #Podcast #Podcaster #ViralPodcast #STEM #Innovation #Technology #Science #ResearchSupport the show

Welcome to a brand-new Beyond the Thesis with Papa PhD experience - the "Papa PhD Gold" format, where we dive into a past episode of the show to explore the intersection of science, communication, and personal growth as a researcher. In this episode, we are joined by Elodie Chabrol, a passionate advocate for science communication and a scientist who emphasizes the importance of stepping back to view the "big picture" in research. Elodie and David Mendes discuss how engaging in science communication can transform a scientist's approach to their work and career, from applying for grants to improving public engagement skills. Elodie Chabrol has a PhD in Neurogenetics and is the international director for the Pint of Science festival. She is also a freelance science communicator involved in different freelance projects like training, moderations and podcasts. Elodie's mission is to make science accessible to everyone, everywhere show the human side of it. Key take-home messages: The Value of Seeing the Big Picture: Elodie shares her insights on how often getting lost in the intricate details of your research, you may neglect the overall context of your work and shares how science communication events encourage scientists to reassess their research from a broader perspective, gaining renewed clarity and purpose.Science Communication as a Learning Tool: By attending events outside your domain, you can gain fresh perspectives and discover innovative ways to communicate your research, as exemplified by Elodie's transformative experience at a physics scicomm event.Benefits of Science Communication for Researchers: Engaging with lay audiences helps scientists hone their skills in turning complex information into accessible narratives. Feedback from public presentations can lead to new insights and strengthen academic skills like grant and paper writing.Experiences from Pint of Science: Elodie shares feedback from scientists who found value in communicating at Pint of Science events, illustrating how taking part in such initiatives can reignite our passion for our own research.Why Listen? Whether you're grappling with the challenge of detailing your research for non-experts or looking to refine how you share your scientific journey, this episode provides valuable strategies to incorporate science communication into your professional toolkit. Unlock the benefits of enhanced communication for career growth and personal satisfaction.Connect with Us: Have thoughts about this episode? Want to recommend a guest for us to interview? Share your voice with us! Visit speakpipe.com/papaphd to leave a voice note. We value every piece of feedback and look forward to featuring some in future episodes.Tune In: Don't miss this insightful conversation aimed at helping you redefine your path Beyond the Thesis. Subscribe to Papa PhD on your favorite podcast platform, and join us next week for another inspiring episode! This episode's links: Website: www.elodiechabrol.com/Twitter: @eloscicomm  Episode Transcript Elodie Chabrol:Sometimes in research, we're losing sight of what we're doing because we are so buried into very deep details on very tiny things that sometimes we are forgetting the big picture. Doing that kind of things brings you back to seeing the big pictures help you it's also helping you finding cool ways of explaining your research, which is never lost because when you're gonna apply for a grant, when you're gonna maybe, apply for a job, apply for whatever, you have to explain the project you want to do and the people in front of you are never gonna be in your domain exactly.David Mendes:Welcome to Beyond the Thesis with Papa PhD, your weekly inspiration for post PhD career development. With me, David Mendes.Elodie Chabrol:When I was watching my lab meetings and I was watching my lab mates presenting their research, most of the times I didn't understand because they ...

Send us a textAbout the guest: Richard Cytowic is a neurologist, poplar science writer and professor at the George Washington University. Episode summary: Nick and Dr. Cytowic discuss: the effects of smart phones and social media on the developing and adult brain; artificial blue light vs. broad spectrum natural light; attention & addiction to technology; sensory overstimulation & “virtual autism”; synesthesia and multimodal sensory perception; and more.Related episodes:M&M 78: Nature vs. Nurture, Neurogenetics, Personality, Autism, Schizophrenia, Synesthesia, Perception, Agency & Free Will | Kevin Mitchell*This content is never meant to serve as medical adviceSupport the showAll episodes (audio & video), show notes, transcripts, and more at the M&M Substack Affiliates: MASA Chips—delicious tortilla chips made from organic corn and grass-fed beef tallow. No seed oils, artificial ingredients, etc. Use code MIND for 20% off. SiPhox Health—Affordable, at-home bloodwork w/ a comprehensive set of key health marker. Use code TRIKOMES for a 10% discount. Lumen device to optimize your metabolism for weight loss or athletic performance. Use code MIND for 10% off. Athletic Greens: Comprehensive & convenient daily nutrition. Free 1-year supply of vitamin D with purchase. Learn all the ways you can support my efforts

Join us as we welcome back Dr. Veera Rajagopal, a discovery scientist at Regeneron with an interest in human genetics and drug target discovery in neuroscience and psychiatry. If you're a regular listener of The Genetics Podcast, you may be familiar with Dr. Veera's annual round-up episodes, and more recently, his quarterly appearances on the show. We're pleased to bring you the latest quarterly roundup, during which Dr. Veera and Patrick walk through the most recent developments in genetics, drug discovery, and precision medicine. In this episode, Dr. Veera and Patrick dive into a wide variety of topics, including: - The evolution of skin color in humans - The potential of a novel tau isoform for Alzheimer's treatment - Protective mechanisms of tomoregulin-1 against herpes simplex virus - The discovery of a new noncoding Mendelian disease mechanism linked to cardiac arrhythmias - A comparative analysis of whole genome versus whole exome sequencing for gene discovery. Tune in now, and don't forget to check out Veera's substack, GWAS Stories, and his Twitter, @doctorveera. Additionally, we're excited to invite you to an in-person meetup for The Genetics Podcast during the ASHG Annual Meeting in Denver, CO! Over the years, we've had the honor of speaking with leading voices across science, industry, patient advocacy, and policy. Now, we're bringing this incredible community together face-to-face. Join us on the evening of Thursday, November 7. To RSVP, visit: https://lu.ma/geneticspodASHG.

In this episode we discuss research on patient and family experiences in neurogenetics. You can find the Journal of Genetic Counseling webpage via onlinelibrary.wiley.com or via the National Society of Genetic Counselors website.    Segment 1: “Individuals' experiences in genetic counseling and predictive testing for familial amyotrophic lateral sclerosis” Connolly Steigerwald is a certified genetic counselor at NYU Langone Health's Division of Neurogenetics and Lysosomal Storage Disorders Program in NYC, where she assists in providing evaluations and genetic counseling for those with suspected or confirmed neurogenetic disorders. Her clinic population includes those with neurodevelopmental disabilities, epilepsies, neuromuscular disorders, dementias, white matter disorders, movement disorders, and lysosomal storage disorders. Connolly holds a Master of Science in Genetic Counseling from Columbia University, where she completed a specialty rotation in neurology with a focus on neurodegenerative and neuromuscular disorders such as amyotrophic lateral sclerosis. Her research interests include predictive genetic testing, lysosomal storage disorders, and implementation of genetic counselor led clinic models. Elizabeth Harrington, MS, CGC, is an ABGC board-certified genetic counselor and Lecturer in the department of Neurology at Columbia University. Ms. Harrington received her graduate degree in human genetics and genetic counseling from the Stanford University School of Medicine.  Ms. Harrington provides genetic counseling expertise in neuromuscular, neurodegenerative, and motor neuron diseases, and specifically provides clinical genetic counseling to patients and families with ALS. In addition to her clinical and academic responsibilities, Ms. Harrington directs the ALS Families Project research study, a presymptomatic natural history study designed to understand the genetic underpinnings of genetic forms of ALS and the impact on affected families. Link to the ALS Families Project: https://clinicaltrials.gov/study/NCT03865420 In this segment we discuss: How the experiences and decision-making processes for ALS risk compare to other neurodegenerative disorders, such as Huntington disease (HD). What influences individuals at risk for familial ALS/FTD to choose predictive genetic testing, including factors like religious affiliation. The psychological impact of testing positive for ALS-associated mutations is compared to those who test negative or opt out of testing, revealing significant emotional differences. Social support networks, whether from family, friends, or healthcare professionals, are critical for those processing genetic test results or managing their risk for ALS/FTD. The importance of integrating psychological care into the predictive genetic testing process to support individuals facing the risk of neurodegenerative diseases. Segment 2: “How parents of children with ataxia-telangiectasia use dynamic coping to navigate cyclical uncertainty” Victoria Suslovitch (Tori) is a genetic counselor and works as a genomic science liaison for the rare disease team at Ambry Genetics. She educates healthcare providers about genetic testing and genomic medicine, and aims to advance access, equity, and quality of genetics services. Prior, Victoria was a research genetic counselor at Boston Children's Hospital, for a study that develops genomically targeted therapies for children with rare neurological diseases. In this role, she worked closely with families of patients with ataxia telangiectasia. She received her Master of Science in Genetic Counseling degree from Boston University, and is certified by the American Board of Genetic Counseling.  Julia Schiller works as a cancer genetic counselor at AdventHealth in Parker, CO. She attended Drake University for her undergraduate degree, and Boston University School of Medicine for her genetic counseling degree and is certified by the American Board of Genetic Counseling. Originally from Minnesota, she now enjoys all the outdoor adventures Colorado has to offer with her partner, Adam, and their dog, Sprocket. Her passionate for health equity and preventative care drive her to create a space for patients where they feel empowered in their own healthcare. Link to the Ataxia Telangiectasia Children's Project (ATCP): https://atcp.org In this segment we discuss: Ataxia-Telangiectasia (A-T) - a pediatric movement disorder characterized by ataxia, immune deficiencies, and a higher risk of cancer, with symptoms often starting in early childhood. The similarities and differences in parental experiences as well as emotional and clinical challenges faced by families The five key themes that emerged: changes in parental responsibilities, shifts in family identity, evolving coping strategies, continuous uncertainty, and the importance of support from various sources. A-T's progressive nature meant that coping and identity changes were ongoing, with parents turning to connections with family, medical teams, and other A-T families. Parents described emotional, logistical, and financial challenges associated with the diagnosis, highlighting the need for supportive and understanding healthcare providers.   Stay tuned for the next new episode of DNA Dialogues! In the meantime, listen to all our episodes Apple Podcasts, Spotify, streaming on the website, or any other podcast player by searching, “DNA Dialogues”.    For more information about this episode visit dnadialogues.podbean.com, where you can also stream all episodes of the show. Check out the Journal of Genetic Counseling here for articles featured in this episode and others.    Any questions, episode ideas, guest pitches, or comments can be sent into DNADialoguesPodcast@gmail.com.    DNA Dialogues' team includes Jehannine Austin, Naomi Wagner, Khalida Liaquat, Kate Wilson, and DNA Today's Kira Dineen. Our logo was designed by Ashlyn Enokian. Our current intern is Sydney Arlen.

Slováci v Poľsku: Marián Smondek, Slovák žijúci v Krakowe; Slováci v Austrálii: Jozef Gécz - odborník v oblasti biológie a genetiky pôsobí na univerzite v Adelaide, kde založil pred rokmi výskumnú skupinu Neurogenetics; Vo svojom výskume sa zameriava najmä na funkcie ľudského mozgu a s tým súvisiace neurologické ochorenia prevažne u detí; Slováci v Chrovátsku: Valčekovanie rovná sa molovanie – maľovanie stien a ich dozdobovanie originálnymi farebnými vzormi pomocou valčekov. Umenie, ktorému sa venujú predovšetkým slovenské ženy a o ktoré je v súčasnosti veľký záujem najmä medzi mladými ľuďmi približuje Sandra Kralj Vukšič, riaditeľka Slovenského kultúrneho centra v Chorvátsku.

Hi everyone it's me Saida in this episode I will be talking about how I been working with my awesome Neuro genetics doctor and how she been helping me and so much more etc

Privahini Bradoo is the co-founder and CEO at Plank — helping companies build and scale AI-enabled engineering teams + training the next generation of computer scientists. Born in India, Privahini immigrated to NZ in her school years. Her time with us down-under was impactful… while pursuing a degree in Biomedical Science, then PhD in Neurogenetics and Drug Discovery at the University of Auckland, she also led the establishment of the Spark business competition (now Velocity); and co-founded Chiasma, an organisation dedicated to linking the biotech academic community with industry.Drawn back off-shore in 2006, Privahini landed a Fulbright scholarship to pursue an MBA at Harvard Business School, and then settled back in the San Francisco Bay Area, joining Lanzatech as one of the first commercial hires in the U.S.In 2011, Privahini co-founded BlueOak Resources to revolutionise how we treat and recycle end-of-life electronics - raising ~$50M from Kliener Perkins and others along the way.In today's episode, we discuss:* From brain science to business: Privahini's unexpected career leap.* the early days of Auckland's startup scene and Velocity business competition. * Lessons from LanzaTech and BlueOak… navigating the complexities of deep tech startups, systems thinking across the supply chain of inputs/outputs, recycling industrial waste. * The future of AI - engineering, revolutionizing remote work, COVID as an accelerating force at Plank.* Optimism in the face of global realities.* How to foster 'force of nature' talent in NZWhere to find Privahini Bradoo:* LinkedIn * Twitter/X * University of Auckland Graduate Stories* KEA - World Class New ZealanderTimestamps:(00:00) Intro(01:43) Privahini's origin story(04:30) Inside the Velocity programme(09:34) Journey at LanzaTech(13:30) The birth of BlueOak(14:51) The reality of e-waste recycling(19:43) Lessons in deep tech(23:11) Founding Plant to help businesses build remote e(25:45) Plank's intelligent engineering strategy(28:10) How to keep up with rapid changes in AI(29:27) Nurturing NZ's entrepreneurial forces of nature(32:07) The second-time founder mindset(35:08) Advice for Kiwi entrepreneurs(36:13) How to help Privahini This is a public episode. If you would like to discuss this with other subscribers or get access to bonus episodes, visit www.diaspora.nz

Welcome to The Genetics Podcast, where Patrick interviews Dr. Andrea Gropman, Professor of Pediatrics and Neurology at George Washington University School of Medicine and Health Sciences and Chief of Neurogenetics at Children's National Hospital. This conversation explores Dr. Gropman's extensive expertise in genetics and how its integration into clinical settings can optimise patient outcomes. We'll also discuss the importance of interdisciplinary collaboration, regulatory and ethical considerations, and the future of genetic research. Tune in for an interesting discussion on the transformative impact of genetics on contemporary medical practice and practical clinical applications.

In this new episode titled "Building a Career Out of Making Science Fun", I sit down with the ever-enthusiastic Elodie Chabrol to dive into the world of science communication. During our conversation, Elodie shares her inspiring journey from a traditional research career to becoming a full-time freelance science communicator.Throughout our conversation, Elodie talks about the challenges and rewards of her career shift and about her overarching goal of countering misinformation through effective science communication. Join us for this energetic conversation and discover how science can be both enlightening and entertaining while bridging the gap between scientific communities and the general public. Elodie Chabrol has a PhD in Neurogenetics and is the international director for the Pint of Science festival. She is also a freelance science communicator involved in different freelance projects like training, moderations and podcasts.Elodie's mission is to make science accessible to everyone, everywhere show the human side of it. What we covered in the interview: Transforming Science Communication: Discover how Elodie has contributed to making science fun and relatable for non-specialist audiences.Pint of Science Festival: Learn about the international festival that brings science to local pubs, offering a relaxed, interactive environment for exchanges with the people behind the research.Inspiring Young Researchers: Elodie discusses how taking part in science communication events helps budding scientists communicate their research effectively and think outside their academic box.Personal Insights: Hear anecdotes from Elodie's journey, including how science communication helped her redefine her identity and broaden her professional horizons.

Although science couldn't (yet) establish a reason for it, Alzheimer's and dementia rates have massively increased over the last 50 years. Regardless of the reason behind that increase, reality tells us these conditions will touch our lives eventually, and today's guest, Dr. Thomas Bird, joins us to teach us the best way to prevent, deal with, and protect ourselves from them. Dr. Thomas Bird, MD, is a neurologist, medical geneticist, and Professor Emeritus from the University of Washington who belonged to the UW Medicine, the UW Division of Neurogenetics, and was the UW Department of Neurology Chief. Part of his over 40 years of work in the field includes identifying new and unusual genetic diseases of the brain and neuromuscular system. He also collaborated with molecular biologists to identify the underlying genes of diseases including Familial Alzheimer's Disease, Frontotemporal Dementia, Huntington's Disease, Hereditary Ataxias, Charcot-Marie-Tooth Neuropathies, Hereditary Spastic Paraplegia, and Muscular Dystrophies. Throughout this episode, Dr. Bird talks about the difference between Alzheimer's and dementia, what changes we can make to prevent them, and recommends healthy habits for people in their 20s to 40s. We also talk about genetic testing, who and when they should get one, causes, red flags, treatments, and more. Tune in to Episode 413 of Becoming Your Best and learn more about these tools that will help you enjoy an active, healthier, and happier second half of your life. Some Questions I Ask: Heart disease and other things have skyrocketed since the '70s. What do you think is the reason behind that increase (11:50) Someone in their 20s, 30s, and 40s? What are things that they ought to be thinking about, brain-health related? (17:50) In This Episode, You Will Learn: Dr. Bird explains the difference between Alzheimer's and dementia (4:20) What are the causes of Alzheimer's and dementia (9:00) Alzheimer's doesn't stand alone (15:40) What should someone interested in taking a genetic test do to get one (22:10) Dr. Bird shares his thoughts on how the fight against these diseases will evolve (32:00) Is there any link between COVID-19 and degenerative diseases? (34:30) Becoming Your Best Resources:Becoming Your Best WebsiteBecoming Your Best University WebsiteBecoming Your Best LibraryEmail: support@becomingyourbest.comBook: Becoming Your Best: The 12 Principles of Highly Successful Leaders Book: Conquer Anxiety: How to Overcome Anxiety and Optimize Your Performance Facebook Group – Conquer Anxiety Hosted on Acast. See acast.com/privacy for more information.

A substantial portion of people with Parkinson's disease (PD) have a family history of the disease, and new findings continue to improve our understanding of relevant genetic variants. These discoveries are key for clarifying the mechanisms that lead to Parkinson's disease as well as the development of new therapies. The Global Parkinson's Genetics Program (GP2) was established to gather and integrate genetic and clinical data from diverse participants around the world to expand our knowledge of the genetic architecture of PD. In this episode, Dr. Christine Klein discusses her experiences as Co-Leader of the Monogenetic Network of GP2, including the early days of setting up this large-scale collaboration, important achievements to date, and priorities and considerations going forward. She also shares recent findings from her own research on genetic variants related to Parkinson's disease. Christine is Director of the Institute of Neurogenetics and of the Section of Clinical and Molecular Neurogenetics at the Department of Neurology, as well as the Schilling Professor of Neurology at the University of Lübeck in Germany. She is also Co-Director of the Monogenetic Network of GP2. This podcast is geared toward researchers and clinicians. If you live with Parkinson's or have a friend or family member with PD, listen to The Michael J. Fox Foundation Parkinson's Podcast. Hear from scientists, doctors and people with Parkinson's on different aspects of life with the disease as well as research toward treatment breakthroughs at https://www.michaeljfox.org/podcasts.

A substantial portion of people with Parkinson's disease (PD) have a family history of the disease, and new findings continue to improve our understanding of relevant genetic variants. These discoveries are key for clarifying the mechanisms that lead to Parkinson's disease as well as the development of new therapies. The Global Parkinson's Genetics Program (GP2) was established to gather and integrate genetic and clinical data from diverse participants around the world to expand our knowledge of the genetic architecture of PD. In this episode, Dr. Christine Klein discusses her experiences as Co-Leader of the Monogenetic Network of GP2, including the early days of setting up this large-scale collaboration, important achievements to date, and priorities and considerations going forward. She also shares recent findings from her own research on genetic variants related to Parkinson's disease. Christine is Director of the Institute of Neurogenetics and of the Section of Clinical and Molecular Neurogenetics at the Department of Neurology, as well as the Schilling Professor of Neurology at the University of Lübeck in Germany. She is also Co-Director of the Monogenetic Network of GP2. This podcast is geared toward researchers and clinicians. If you live with Parkinson's or have a friend or family member with PD, listen to The Michael J. Fox Foundation Parkinson's Podcast. Hear from scientists, doctors and people with Parkinson's on different aspects of life with the disease as well as research toward treatment breakthroughs at https://www.michaeljfox.org/podcasts.

Chief Executive Officer Paul Rayson welcomes Associate Professor Gina Ravenscroft. Gina is an Associate Professor in Neurogenetics at the Harry Perkins Institute of Medical Research in Perth. Her research interests are in rare genetic diseases, with a particular focus on neurogenetic diseases in babies and children. Assoc. Prof Ravenscroft and her team have identified more than 20 novel human disease genes in recent years. Gina brings a wealth of expertise to our conversation, tune in to explore the fascinating insights of Associate Professor Gina Ravenscroft as she shares stories of international collaboration and the direct impact of her research into rare genetic diseases.This is a Hearts & Minds Podcast, in partnership with Equity Mates MediaFor more information about HM1 and the upcoming Sohn Hearts & Minds Conference visit our website hereDisclaimer:This communication has been prepared by Hearts and Minds Investments Limited (ABN 61 628 753 220). In preparing this publication the investment objectives, financial situation or particular needs of an individual have not been considered. You should not rely on the opinions, advice, recommendations and other information contained in this publication alone. The inclusion of third-party content does not in any way imply any form of endorsement by HM1 of the products or services provided by persons or organisations who are responsible for the third-party content. This publication has been prepared to provide you with general information only. It is not intended to take the place of professional advice and you should not take action on specific issues in reliance on this information. Past performance is not a reliable indicator of future performance. Hosted on Acast. See acast.com/privacy for more information.

Slováci v Poľsku: Marián Smondek, Slovák žijúci v Krakowe; Slováci v Austrálii: Jozef Gécz - odborník v oblasti biológie a genetiky pôsobí na univerzite v Adelaide, kde založil pred rokmi výskumnú skupinu Neurogenetics; Vo svojom výskume sa zameriava najmä na funkcie ľudského mozgu a s tým súvisiace neurologické ochorenia prevažne u detí; Slováci v Chrovátsku: Valčekovanie rovná sa molovanie – maľovanie stien a ich dozdobovanie originálnymi farebnými vzormi pomocou valčekov. Umenie, ktorému sa venujú predovšetkým slovenské ženy a o ktoré je v súčasnosti veľký záujem najmä medzi mladými ľuďmi približuje Sandra Kralj Vukšič, riaditeľka Slovenského kultúrneho centra v Chorvátsku;

CENTOGENE's Prof. Peter Bauer and Dr. Jorge Pinto Basto join host Ben Legg to look back on 25 Years since the human genome project was concluded. Today, we are discussing the Human Genome Project – looking at the initial impact, the advancements in the past 20 years, and what the future of genetics and rare disease patient care could look like. Before joining CENTOGENE, Jorge served as the Director of the Molecular Diagnostics and Genomics Labs at CGC Genetics. He holds a medical degree from the University of Porto and is specialized in Rare Disease Genetics, Neurogenetics, Dysmorphology, and Molecular Genetics. Listen in as Dr. Basto and Prof. Bauer share their insights into their journey with genomic testing 25 years later.

In September 2022, two New Zealand patients became the first in the world to participate in a phase 1 clinical trial testing a new therapy for a rare neurogenetic condition called myotonic dystrophy. Claire Concannon learns about the trial, and how a new Neurogenetic Registry and Biobank covering 70 conditions is helping to connect New Zealand patients with international research.

Two New Zealand patients will be the first participants in the world to join a phase 1 clinical trial to test the safety of a new therapy for myotonic dystrophy – a rare neurogenetic condition. It's one example of how New Zealand's neurogenetic registry and biobank is helping patients here gain access to international clinical trials. Claire Concannon learns more.

Each month, our Carrier Connections program features a different X-linked condition with the goal to increase awareness and education of X-linked conditions and how they impact females. This month, we are featuring ornithine transcarbamylase (OTC) deficiency. OTC deficiency is an X-linked genetic disorder marked by a complete or partial lack of the enzyme ornithine transcarbamylase. This results in the accumulation of ammonia in the bloodstream and causes complications in the nervous system, resulting in a range of severe to mild symptoms. Approximately 20% of OTC females experience symptoms. Some females do not express excess ammonia levels until pregnancy. Females who do develop symptoms in childhood often experience headaches after protein ingestion. A study determined that girls with OTC deficiency may exhibit episodes of hyperammonemic encephalopathy, or ammonia buildup in the brain, and cognitive decline. Today, we are joined by Andrea Gropman, M.D., FAAP, FACMG, FANA. Dr. Gropman is the Chief of Neurogenetics and Neurodevelopmental Pediatrics at Children's National. She is also is the principal investigator of the Urea Cycle Disorders Consortium (UCDC) and the UCDC imaging consortium and the deputy clinical director of the Mito EpiGen Program. Her research interest focuses on establishing biomarkers of neurological injury in patients with inborn errors of metabolism, such as urea cycle disorders and mitochondrial disorders, using specialized neuroimaging modalities and cell markers. Carrier Connections is sponsored by Horizon Therapeutics, Sanofi, and Ultragenyx Pharmaceutical. For more information about our organization, check out rememberthegirls.org.

In this episode of the “Inside Rare Diseases: On a mission for life-changing answers podcast,” Dr. Christine Klein, Head of the Neurogenetic Institute of the University of Lübeck, and CENTOGENE's Prof. Peter Bauer, M.D., join host Ben Legg to talk about the latest insights into Parkinson's Disease (PD). Dr. Klein is a Professor of Neurology and Neurogenetics. She has served as the Chair of the Congress Scientific Program Committee of the International Parkinson and Movement Disorder Society and President of the German Neurological Society and currently acts as Chair-Elect of the European Section of the International Parkinson and Movement Disorder Society. Listen in as Dr. Klein and Prof. Bauer share insights into the diagnosis, prognosis, and treatment of Parkinson's Disease.

Personalised medicine tailored to the individual's health needs is not exactly new, but it's a field that's rapidly growing and garnering much attention in various fields of health, especially in cancer treatment. On this episode of Brain Waves, we break down the role of genetics in personalised medicine and the future of personalised medicine in neurological diseases, with Dr Azlina Ahmad Annuar, neurogeneticist, and Dr Ruth Chia from Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging.

Personalised medicine tailored to the individual's health needs is not exactly new, but it's a field that's rapidly growing and garnering much attention in various fields of health, especially in cancer treatment. On this episode of Brain Waves, we break down the role of genetics in personalised medicine and the future of personalised medicine in neurological diseases, with Dr Azlina Ahmad Annuar, neurogeneticist, and Dr Ruth Chia from Neuromuscular Diseases Research Section, Laboratory of Neurogenetics, National Institute on Aging.

Huberman Lab Podcast Notes “Learning how to produce speech is a more complex learning ability than say learning how to walk or do tricks and jumps that dogs do.” – Dr. Erich JarvisOnly vocal-learning (ability to imitate sounds) species can learn how to danceHumans have a striking similarity to songbirds in terms of function, structure, and genome of languageHumans use our voices for semantic, abstract communication but we use learned to dance for effective emotional bonding communicationWhen you write something out, you're speaking it to yourself in low currentsThe evolution of spoken language evolved for singing and emotional mate attraction first, then was used for abstract communication; so, it can be easier to do things with singing as opposed to speakingRemedies for stutter: behavioral therapy, learning to speak slower, tapping out a rhythm – basically, sensory-motor integration tools – controlling what you hear with outputGoing from thought to language to motor action (e.g., writing) takes four brain pathways working in coordinationSpeech and movement pathways are adjacent – dancing/exercising/jogging/moving can help you think and stay cognitively intactRead the full notes @ podcastnotes.orgMy guest this episode is Dr. Erich Jarvis, PhD—Professor and the Head of the Laboratory of Neurogenetics of Language at Rockefeller University and Investigator with the Howard Hughes Medical Institute (HHMI). Dr. Jarvis' research spans the molecular and genetic mechanisms of vocal communication, comparative genomics of speech and language across species and the relationship between speech, language and movement. We discuss the unique ability of humans (and certain animal species) to learn and communicate using complex language, including verbal speech production and the ability to interpret both written and spoken language. We also discuss the connections between language, singing and dance and why song may have evolved before language. Dr. Jarvis also explains some of the underlying biological and genetic components of stutter/speech disorders, non-verbal communication, why it's easiest to learn a language as a child and how individuals can learn multiple languages at any age. This episode ought to be of interest to everyone interested in the origins of human speech, language, music and culture and how newer technology, such as social media and texting, change our brains.  Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman InsideTracker: https://insidetracker.com/huberman ROKA: https://roka.com/huberman LMNT: https://drinklmnt.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Erich Jarvis & Vocal Communication (00:03:43) Momentous Supplements  (00:04:36) InsideTracker, ROKA, LMNT  (00:08:01) Speech vs. Language, Is There a Difference?   (00:10:55) Animal Communication, Hand Gestures & Language  (00:15:25) Vocalization & Innate Language, Evolution of Modern Language     (00:21:10) Humans & Songbirds, Critical Periods, Genetics, Speech Disorders  (00:27:11) Innate Predisposition to Learn Language, Cultural Hybridization (00:31:34) Genes for Speech & Language (00:35:49) Learning New or Multiple Languages, Critical Periods, Phonemes  (00:41:39) AG1 (Athletic Greens)  (00:42:52) Semantic vs. Effective Communication, Emotion, Singing (00:47:32) Singing, Link Between Dancing & Vocal Learning  (00:52:55) Motor Theory of Vocal Learning, Dance  (00:55:03) Music & Dance, Emotional Bonding, Genetic Predispositions (01:04:11) Facial Expressions & Language, Innate Expressions (01:09:35) Reading & Writing  (01:15:13) Writing by Hand vs. Typing, Thoughts & Writing (01:20:58) Stutter, Neurogenetics, Overcome Stutter, Conversations (01:26:58) Modern Language Evolution: Texting, Social Media & the Future (01:36:26) Movement: The Link to Cognitive Growth  (01:40:21) Comparative Genomics, Earth Biogenome Project, Genome Ark, Conservation (01:48:24) Evolution of Skin & Fur Color (01:51:22) Dr. Erich Jarvis, Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Momentous Supplements, AG1 (Athletic Greens), Instagram, Twitter Neural Network Newsletter, Huberman Lab Clips Title Card Photo Credit: Mike Blabac Disclaimer

Huberman Lab: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- My guest this episode is Dr. Erich Jarvis, PhD—Professor and the Head of the Laboratory of Neurogenetics of Language at Rockefeller University and Investigator with the Howard Hughes Medical Institute (HHMI). Dr. Jarvis' research spans the molecular and genetic mechanisms of vocal communication, comparative genomics of speech and language across species and the relationship between speech, language and movement. We discuss the unique ability of humans (and certain animal species) to learn and communicate using complex language, including verbal speech production and the ability to interpret both written and spoken language. We also discuss the connections between language, singing and dance and why song may have evolved before language. Dr. Jarvis also explains some of the underlying biological and genetic components of stutter/speech disorders, non-verbal communication, why it's easiest to learn a language as a child and how individuals can learn multiple languages at any age. This episode ought to be of interest to everyone interested in the origins of human speech, language, music and culture and how newer technology, such as social media and texting, change our brains.  Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman InsideTracker: https://insidetracker.com/huberman ROKA: https://roka.com/huberman LMNT: https://drinklmnt.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Erich Jarvis & Vocal Communication (00:03:43) Momentous Supplements  (00:04:36) InsideTracker, ROKA, LMNT  (00:08:01) Speech vs. Language, Is There a Difference?   (00:10:55) Animal Communication, Hand Gestures & Language  (00:15:25) Vocalization & Innate Language, Evolution of Modern Language     (00:21:10) Humans & Songbirds, Critical Periods, Genetics, Speech Disorders  (00:27:11) Innate Predisposition to Learn Language, Cultural Hybridization (00:31:34) Genes for Speech & Language (00:35:49) Learning New or Multiple Languages, Critical Periods, Phonemes  (00:41:39) AG1 (Athletic Greens)  (00:42:52) Semantic vs. Effective Communication, Emotion, Singing (00:47:32) Singing, Link Between Dancing & Vocal Learning  (00:52:55) Motor Theory of Vocal Learning, Dance  (00:55:03) Music & Dance, Emotional Bonding, Genetic Predispositions (01:04:11) Facial Expressions & Language, Innate Expressions (01:09:35) Reading & Writing  (01:15:13) Writing by Hand vs. Typing, Thoughts & Writing (01:20:58) Stutter, Neurogenetics, Overcome Stutter, Conversations (01:26:58) Modern Language Evolution: Texting, Social Media & the Future (01:36:26) Movement: The Link to Cognitive Growth  (01:40:21) Comparative Genomics, Earth Biogenome Project, Genome Ark, Conservation (01:48:24) Evolution of Skin & Fur Color (01:51:22) Dr. Erich Jarvis, Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Momentous Supplements, AG1 (Athletic Greens), Instagram, Twitter Neural Network Newsletter, Huberman Lab Clips Title Card Photo Credit: Mike Blabac Disclaimer

My guest this episode is Dr. Erich Jarvis, PhD—Professor and the Head of the Laboratory of Neurogenetics of Language at Rockefeller University and Investigator with the Howard Hughes Medical Institute (HHMI). Dr. Jarvis' research spans the molecular and genetic mechanisms of vocal communication, comparative genomics of speech and language across species and the relationship between speech, language and movement. We discuss the unique ability of humans (and certain animal species) to learn and communicate using complex language, including verbal speech production and the ability to interpret both written and spoken language. We also discuss the connections between language, singing and dance and why song may have evolved before language. Dr. Jarvis also explains some of the underlying biological and genetic components of stutter/speech disorders, non-verbal communication, why it's easiest to learn a language as a child and how individuals can learn multiple languages at any age. This episode ought to be of interest to everyone interested in the origins of human speech, language, music and culture and how newer technology, such as social media and texting, change our brains.  Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman InsideTracker: https://insidetracker.com/huberman ROKA: https://roka.com/huberman LMNT: https://drinklmnt.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Erich Jarvis & Vocal Communication (00:03:43) Momentous Supplements  (00:04:36) InsideTracker, ROKA, LMNT  (00:08:01) Speech vs. Language, Is There a Difference?   (00:10:55) Animal Communication, Hand Gestures & Language  (00:15:25) Vocalization & Innate Language, Evolution of Modern Language     (00:21:10) Humans & Songbirds, Critical Periods, Genetics, Speech Disorders  (00:27:11) Innate Predisposition to Learn Language, Cultural Hybridization (00:31:34) Genes for Speech & Language (00:35:49) Learning New or Multiple Languages, Critical Periods, Phonemes  (00:41:39) AG1 (Athletic Greens)  (00:42:52) Semantic vs. Effective Communication, Emotion, Singing (00:47:32) Singing, Link Between Dancing & Vocal Learning  (00:52:55) Motor Theory of Vocal Learning, Dance  (00:55:03) Music & Dance, Emotional Bonding, Genetic Predispositions (01:04:11) Facial Expressions & Language, Innate Expressions (01:09:35) Reading & Writing  (01:15:13) Writing by Hand vs. Typing, Thoughts & Writing (01:20:58) Stutter, Neurogenetics, Overcome Stutter, Conversations (01:26:58) Modern Language Evolution: Texting, Social Media & the Future (01:36:26) Movement: The Link to Cognitive Growth  (01:40:21) Comparative Genomics, Earth Biogenome Project, Genome Ark, Conservation (01:48:24) Evolution of Skin & Fur Color (01:51:22) Dr. Erich Jarvis, Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Momentous Supplements, AG1 (Athletic Greens), Instagram, Twitter Neural Network Newsletter, Huberman Lab Clips Title Card Photo Credit: Mike Blabac Disclaimer

Kristen Willeumier, Ph.D.Kristen Willeumier, PhD, is a neuroscientist with research expertise on how diet, lifestyle, nutrition and sports related concussions impact brain health and longevity. Dr. Willeumier served as the Director of Neuroimaging Research for the Amen Clinics from 2009-2016 exploring the role of brain SPECT imaging in clinical practice. She has authored or co-authored 52 scientific publications in peer reviewed journals. Areas of published research include traumatic brain injury, posttraumatic stress disorder, autism, biomarkers of suicide, obesity, gender differences in brain function, clinical outcomes and brain rehabilitation. Together with colleagues, she led a clinical research trial investigating the long-term effects of repetitive subconcussive impacts in NFL football players. Subsequent work focused on therapeutic approaches to rehabilitate brain function in athletes. Dr.Willeumier is currently the on the Scientific Advisory Board of Black Brain Health, LLC, a brain health organization focused on promoting enhanced cognition and neuroprotection and is a Media Spokesperson for CogGevity™ Advanced Brain Nutrition. She also holds a position on the Scientific Advisory Board of Tate Technology, LLC, a sports safety and technology licensing company. Dr.Willeumier is a Senior Research Fellow with the Society for Brain Mapping and Therapeutics and sits on the Scientific Committee for the 2018 World Brain Mapping Congress developing a Brain Health and Fitness Initiative.Dr. Willeumier conducted her graduate research in the laboratory of Neurophysiology at the University of California, Los Angeles and the laboratory of Neurogenetics at Cedars-Sinai Medical Center using live cell imaging to investigate mechanisms of synaptic signaling in Parkinson's disease. She received MS degrees in Physiological science and Neurobiology and a PhD degree in Neurobiology from the University of California, Los Angeles. She was a post-doctoral fellow in the Department of Neurology at Cedars-Sinai Medical Center where she continued her work in the field of neurodegenerative disease. She was the recipient of the prestigious NIH fellowship from the National Institute of Mental Health to study the molecular mechanisms underlying Parkinson's disease and has presented her work at national and international scientific meetings including the Society for Neuroscience and Gordon Research Conference in Hong Kong.

Kristen Willeumier, Ph.D.Kristen Willeumier, PhD, is a neuroscientist with research expertise on how diet, lifestyle, nutrition and sports related concussions impact brain health and longevity. Dr. Willeumier served as the Director of Neuroimaging Research for the Amen Clinics from 2009-2016 exploring the role of brain SPECT imaging in clinical practice. She has authored or co-authored 52 scientific publications in peer reviewed journals. Areas of published research include traumatic brain injury, posttraumatic stress disorder, autism, biomarkers of suicide, obesity, gender differences in brain function, clinical outcomes and brain rehabilitation. Together with colleagues, she led a clinical research trial investigating the long-term effects of repetitive subconcussive impacts in NFL football players. Subsequent work focused on therapeutic approaches to rehabilitate brain function in athletes. Dr.Willeumier is currently the on the Scientific Advisory Board of Black Brain Health, LLC, a brain health organization focused on promoting enhanced cognition and neuroprotection and is a Media Spokesperson for CogGevity™ Advanced Brain Nutrition. She also holds a position on the Scientific Advisory Board of Tate Technology, LLC, a sports safety and technology licensing company. Dr.Willeumier is a Senior Research Fellow with the Society for Brain Mapping and Therapeutics and sits on the Scientific Committee for the 2018 World Brain Mapping Congress developing a Brain Health and Fitness Initiative.Dr. Willeumier conducted her graduate research in the laboratory of Neurophysiology at the University of California, Los Angeles and the laboratory of Neurogenetics at Cedars-Sinai Medical Center using live cell imaging to investigate mechanisms of synaptic signaling in Parkinson's disease. She received MS degrees in Physiological science and Neurobiology and a PhD degree in Neurobiology from the University of California, Los Angeles. She was a post-doctoral fellow in the Department of Neurology at Cedars-Sinai Medical Center where she continued her work in the field of neurodegenerative disease. She was the recipient of the prestigious NIH fellowship from the National Institute of Mental Health to study the molecular mechanisms underlying Parkinson's disease and has presented her work at national and international scientific meetings including the Society for Neuroscience and Gordon Research Conference in Hong Kong.

Nick talks to neuroscientist & geneticist Dr. Kevin Mitchell about: 'Nature vs. Nurture,' the genetics of brain development, autism & schizophrenia, human brain and psychological variation, synesthesia, agency & free will, and more.USEFUL LINKSSign up for the weekly Mind & Matter newsletter[https://mindandmatter.substack.com/?sort=top]Follow Nick's work through Linktree:[https://linktr.ee/trikomes]DoubleBlind Magazine, a leading source of news, information, and education about psychedelics. Use code MINDMATTER for 20% site-wide.[https://www.doubleblindmag.com/mindmatter]Athletic Greens, comprehensive daily nutrition (Free 1-year supply Vitamin D w/ purchase)[https://www.athleticgreens.com/mindandmatter]Organize your digital highlights & notes w/ Readwise (2 months free w/ sub)[https://readwise.io/nickjikomes/]Support the show

In this week's episode, Rachel is joined by Jonathan de Potter who is the founder and CEO of Behold Retreats which is a wellness service that facilitates journeys of self-discovery and transformation, supported by the scientifically proven benefits of plant medicine therapy. Johnathan shares his journey of making his way through the corporate world and climbing that ladder until one day he realizes there was more to his life and what he was doing was not it. From here he packed his bag and traveled across South America and had his first ayahuasca journey.He shares a bit about his journey with mother aya and the various ways she calls us to her. He also touches on certain things to look for and be aware of when considering working with the medicine. You can connect with Johnathan through the following links:https://www.behold-retreats.com/Today's Sponsors: Forij Granola: Start your day with mental focus and natural energy from whole food ingredients & anti-inflammatory functional mushrooms. Enjoy the handcrafted mouth-watering flavors that leverage spice for flavor rather than sugar. Feel the difference with 100% real ingredients & anti-inflammatory mushroom extracts that provide real energy & focus benefits. Eat guilt-free knowing this is the lowest sugar granola on the market. Visit forij.co and enter liveraw15 for 15% off.Rachel would love to hear what you enjoyed most about this conversation. Let her know through the following:IG: @liveyourrawlifeF: Live Your RAW Life Y: Live Your RAW LifeE: liveyourrawlife@gmail.comWeb: www.liveyourrawlife.comIf you'd like to support this podcast you can do so through:Patreon link:https://www.patreon.com/liveyourrawlifeIf something resonated with you from this week's episode please subscribe to the show and leave a review while you are there. Every time a review or rating is received it opens up the platform that allows the show to reach a wider range of listeners. Your support is greatly appreciated.

In this week's podcast, Neurology Today's editor-in-chief discusses the challenges and opportunities of teleneurology in rural areas, the effect of childhood trauma on neurologic disorders, and genetics advances in neurology.

Scientists have been using sewage to track COVID-19 in the community throughout the pandemic and even now as the virus enters the endemic stage. Using wastewater surveillance helps scientists determine the prevalence of the virus and what variants are present in the Las Vegas Valley. We talk with Dr. Dan Gerrity, Principal Research Laboratory Scientist for the Southern Nevada Water Authority (SNWA), and Dr. Edwin Oh, UNLV Associate Professor of Neurogenetics and Precision Medicine Lab, about how their wastewater surveillance research helped health professionals and elected officials during the COVID-19 pandemic. The two researchers share their “Ah Ha!” moments and the future of wastewater surveillance on episode 24 of Water Smarts Podcast, “AH HA! How the pandemic led to new insights for wastewater surveillance.”Hosts: Bronson Mack and Crystal Zuelkehttps://www.snwa.com/https://empower.unlv.edu/

Description: Margaret Elizabeth Ross, M.D., Ph.D. is a Nathan Cummings professor in neurology and director of the Center for Neurogenetics at the Feil Family Brain and Mind Research Institute at Weill Cornell Medicine in New York. To learn more, check out the Ross Lab website! 1:30 Introduction 4:00 An Intro to AI 10:15 What are Neural Tube Defects? 16:30 Publications from the Ross Lab 21:00 The Ross Lab's Use of AI 30:00 Clinical Applications of Genetic Research 31:00 Spina Bifida Outcomes 32:00 Health Equity in Genetics 36:40 What's Next? 42:00 What's the future of AI in Medicine? 43:40 Advice for your Past Self 45:00 Advice for Medical Student/Physicians 48:00 Final Words of Wisdom Intro Music - Windows96 - Caligula (song used with permission from artist). Host: Madeline Ahern Producer: Melanie Bussan Cover Art: Saurin Kantesaria Follow us on twitter @themamlpodcast Email us! contact@themamlpodcast.com Looking for industry sponsors!

As neurodegenerative disorders such as Parkinson's and Alzheimer's disease wreak havoc on the brain and on our aging society, scientists race to identify factors that trigger neuronal demise and figure out how to stop them. Because neurons can't be replaced, it is important to detect signs of stress in the brain early, before brain cells pass the point of no return. Scientists recently combined lipidomics with genetics and discovered that lipids are an underestimated player in neurodegeneration. In this episode narrated by Niki Spahich, Nele Haelterman from The Scientist's Creative Services team spoke with Melissa Vos, a neuroscientist at the Institute of Neurogenetics at the University of Lübeck, to learn more.   The Scientist Speaks is a podcast produced by The Scientist's Creative Services Team. Our podcast is by scientists and for scientists. Once a month, we bring you the stories behind news-worthy molecular biology research.

Dr. Kristen Willeumier, trailblazing Neuroscientist and Brain Imaging Expert on How to Biohack Your Brain, Jumping Off of Waterfalls in the Dark,  How Contact-Based Sport Causes Brain Damage in Athletes & How to Reverse It, Skills Learned While Show-Jumping With Olympians, and Other Hacks for Peak Cognitive Performance and much more! Dr. Kristen Willeumier (@kwilleumier) conducted her graduate research in the laboratory of Neurophysiology at the University of California, Los Angeles, and the laboratory of Neurogenetics at Cedars-Sinai Medical Center.  She received MS degrees in Physiological science and Neurobiology and a Ph.D. degree in Neurobiology from the University of California, Los Angeles. She was a postdoctoral scientist in the Department of Neurology at Cedars-Sinai Medical Center where she continued her work in the field of neurodegenerative disease.  She was the recipient of a National Research Service Award Fellowship from the National Institutes of Health and has presented her work internationally.  Having served as the Director of Neuroimaging Research for the Amen Clinics, she led the efforts in utilizing imaging technologies to understand the neurobiological correlates underlying psychiatric disorders.  In this capacity, she oversaw many pioneering studies, including a clinical research trial investigating the long-term effects of repetitive subconcussive impacts in National Football League players, and developed a protocol to successfully reverse brain damage and improve cognitive health! Dr. Willeumier is widely published in peer-reviewed journals including The Journal of Alzheimer's Disease, Translational Psychiatry, and The Journal of Neuroscience. Please enjoy! If you enjoyed this episode, please hit SUBSCRIBE to the podcast to get your weekly dose of longevity & lifestyle inspiration! I would also love to hear from you so please leave a comment to let me know what you think or reach out on Instagram @longevityandlifestyle! Choose to live well! Warmest, Claudia x

Dr. Kristen Willeumier, trailblazing Neuroscientist and Brain Imaging Expert on How to Biohack Your Brain, Jumping Off of Waterfalls in the Dark,  How Contact-Based Sport Causes Brain Damage in Athletes & How to Reverse It, Skills Learned While Show-Jumping With Olympians, and Other Hacks for Peak Cognitive Performance and much more! Dr. Kristen Willeumier (@kwilleumier) conducted her graduate research in the laboratory of Neurophysiology at the University of California, Los Angeles, and the laboratory of Neurogenetics at Cedars-Sinai Medical Center.  She received MS degrees in Physiological science and Neurobiology and a Ph.D. degree in Neurobiology from the University of California, Los Angeles. She was a postdoctoral scientist in the Department of Neurology at Cedars-Sinai Medical Center where she continued her work in the field of neurodegenerative disease.  She was the recipient of a National Research Service Award Fellowship from the National Institutes of Health and has presented her work internationally.  Having served as the Director of Neuroimaging Research for the Amen Clinics, she led the efforts in utilizing imaging technologies to understand the neurobiological correlates underlying psychiatric disorders.  In this capacity, she oversaw many pioneering studies, including a clinical research trial investigating the long-term effects of repetitive subconcussive impacts in National Football League players, and developed a protocol to successful reverse brain damage and improve cognitive health! Dr. Willeumier is widely published in peer-reviewed journals including The Journal of Alzheimer's Disease, Translational Psychiatry, and The Journal of Neuroscience. Please enjoy! If you enjoyed this episode, please hit SUBSCRIBE to the podcast to get your weekly dose of longevity & lifestyle inspiration! I would also love to hear from you so please leave a comment to let me know what you think or reach out on instagram @longevityandlifestyle! Choose to live well! Warmest, Claudia x

You're listening to the voice of Dr. Kathy Swoboda, who is the Katherine B. Sims MD Endowed Chair in Neurogenetics and Director of the Neurogenetics Unit in the Center for Genomic Medicine at the Massachusetts General Hospital and Harvard Medical School. Her research and clinical activities are dedicated to the diagnosis and treatment of inherited motor disorders of childhood-onset, with a particular focus on genotype-phenotype studies documenting onset and timing of progressive denervation in infants with Spinal Muscular Atrophy, also known as SMA.   Dr. Swoboda collaborated closely with Cure SMA in helping to obtain critical data necessary to support the addition of SMA to the Newborn Screening Recommended Universal Screening Panel (RUSP), and with the American College of Medical Genetics and Genomics (ACMG) and Newborn Screening Translational Research Network also known as NBSTRN to build tools suitable for use for newborn screening follow-up for infants with SMA.   In this episode, Dr. Swoboda will describe the important research efforts that led to newborn screening for spinal muscular atrophy (SMA) and how different interventions are impacting the lives of newborns with SMA. Dr. Swoboda has played a significant role in getting SMA to be added to the recommended uniform screening panel (RUSP) and her journey from a clinician to a researcher is truly inspiring. So, listen on.   Interview Questions with Dr. Swoboda: 1. Could you tell us what is spinal muscular atrophy (also known as SMA)? 2. You and your research were involved in SMA being recommended to nationwide screening. Can you describe this experience? 3. How have the families you work with been impacted by the addition of SMA to nationwide newborn screening? 4.  What is the importance of early identification and treatment by NBS. What are current interventions for individuals with the SMA? 5. Why is NBS research for SMA important? 6. How has NBSTRN helped your research in SMA? 7. What career advice could you give to someone interested in being a clinician-researcher like yourself? 8. What does NBS research mean to you? To learn more about newborn screening research, visit www.nbstrn.org

Dr. Ahmad Hariri is Professor of Psychology & Neuroscience at Duke University, where he is also the Director of the Laboratory of NeuroGenetics. Dr. Hariri recently published an important paper on the test-retest reliability of common task-fMRI measures. This received attention in the field and from the popular media and generated useful discussions. In this podcast Peter and Ahmad discuss the implications of this paper and how to address the challenges it presents and continue to move the field forward. This is an informative and positive discussion about how to collectively address these issues as a field.

For much of the history of neurology, diagnosing a genetic disease meant giving bad news. Genetic meant incurable, often fatal. On past shows, we've talked about how this narrative is changing for certain monogenic diseases like Huntington's Disease, where emerging gene therapies offer hope for a cure. But what hope can the field of neurogenetics offer to patients with more complex diseases with both genetic and environmental risk factors, like Alzheimer's? Our guest today, Dr. M. Elizabeth Ross, is Professor of Neurology and Neuroscience in the Brain and Mind Research Institute and Director of the Center for Neurogenetics at Weill Cornell Medicine. Her lab works on the genetics of neurologic diseases affecting humans at every stage of the lifecycle. Today she'll help us understand the role of genetics in a range of neurodegenerative diseases -- and how and when clinicians should incorporate genetic considerations into patient care. Series 2, Episode 8

Kristen Willeumier, Ph.D. Kristen Willeumier, PhD, is a neuroscientist with research expertise on how diet, lifestyle, nutrition and sports related concussions impact brain health and longevity. Dr. Willeumier served as the Director of Neuroimaging Research for the Amen Clinics from 2009-2016 exploring the role of brain SPECT imaging in clinical practice. She has authored or co-authored 52 scientific publications in peer reviewed journals. Areas of published research include traumatic brain injury, posttraumatic stress disorder, autism, biomarkers of suicide, obesity, gender differences in brain function, clinical outcomes and brain rehabilitation. Together with colleagues, she led a clinical research trial investigating the long-term effects of repetitive subconcussive impacts in NFL football players. Subsequent work focused on therapeutic approaches to rehabilitate brain function in athletes. Dr.Willeumier is currently the on the Scientific Advisory Board of Black Brain Health, LLC, a brain health organization focused on promoting enhanced cognition and neuroprotection and is a Media Spokesperson for CogGevity™ Advanced Brain Nutrition. She also holds a position on the Scientific Advisory Board of Tate Technology, LLC, a sports safety and technology licensing company. Dr.Willeumier is a Senior Research Fellow with the Society for Brain Mapping and Therapeutics and sits on the Scientific Committee for the 2018 World Brain Mapping Congress developing a Brain Health and Fitness Initiative. Dr. Willeumier conducted her graduate research in the laboratory of Neurophysiology at the University of California, Los Angeles and the laboratory of Neurogenetics at Cedars-Sinai Medical Center using live cell imaging to investigate mechanisms of synaptic signaling in Parkinson's disease. She received MS degrees in Physiological science and Neurobiology and a PhD degree in Neurobiology from the University of California, Los Angeles. She was a post-doctoral fellow in the Department of Neurology at Cedars-Sinai Medical Center where she continued her work in the field of neurodegenerative disease. She was the recipient of the prestigious NIH fellowship from the National Institute of Mental Health to study the molecular mechanisms underlying Parkinson's disease and has presented her work at national and international scientific meetings including the Society for Neuroscience and Gordon Research Conference in Hong Kong. Our radio shows archives and programming include: A Different Perspective with Kevin Randle; Alien Cosmic Expo Lecture Series; Alien Worlds Radio Show; Connecting with Coincidence with Dr. Bernard Beitman, MD; Dick Tracy; Dimension X; Exploring Tomorrow Radio Show; Flash Gordon; Jet Jungle Radio Show; Journey Into Space; Know the Name with Sharon Lynn Wyeth; Lux Radio Theatre - Classic Old Time Radio; Mission Evolution with Gwilda Wiyaka; Paranormal StakeOut with Larry Lawson; Ray Bradbury - Tales Of The Bizarre; Sci Fi Radio Show; Seek Reality with Roberta Grimes; Space Patrol; Stairway to Heaven with Gwilda Wiyaka; The 'X' Zone Radio Show with Rob McConnell; and many other! That's The ‘X' Zone Broadcast Network Shows and Archives - https://www.spreaker.com/user/xzoneradiotv *** AND NOW *** The ‘X' Zone TV Channel on SimulTV - www.simultv.com The ‘X' Chronicles Newspaper - www.xchroniclesnewspaper.com

ANNOUNCEMENT! Dissolve-It-All - breaking down scar tissue, inflammation and calcification PUFA Protect - Eliminating a lifetime of a high PUFA diet Use discount code EHR15! GET 10% OFF THE AQUACURE HYDROGEN BROWN'S GAS MACHINE WITH CODE EHR10 (LISTEN TO THAT SHOW) If you'd like to purchase an Aquacure hydrogen and Brown's gas device, we negotiated a 10% discount for you! Use code EHR10 on: https://eagle-research.com/product/ac50/ As life would have it, we did two shows in a row all about hydrogen and brown's gas. Maybe God is telling us something? When things happen in my life like this I always wonder if God is trying to send me a message. Either way we talked more about hydrogen than brown's gas in this particular show but it was still loads of fun. Tyler likes to get really into the science so we really broke down what happens in the body when a person drinks or inhales molecular hydrogen. We also discussed deuterium, tritium and other isotopes and how they impact the mitochondria. The whole ideas is to not just create more ATP with the mitochondria we have, but also how can we actually create more mitochondria and get those new mitochondria operating properly and create energy in the cell. So lots to discuss here. How can we keep more mitochondria, how can we improve the electron transport chain to be able to create 4th stage water, better utilize oxygen and also create more ATP? If we can answer those questions and solve those problems, my believe is that we can extend lifespan by many many decades. The name of the game when it comes to health is ATP production and having healthy mitochondrial energy to deal with oxygen. When we do that, we live longer, healthier disease free lives. Tyler LeBaron talks about how hydrogen can impact mitochondrial health! I hope you enjoy! Please share with your friends will you? :) On Last Thing! As always your support via your donations and bookmarking our Amazon link to use each time you purchase is how we keep our show going. Thank you for bookmarking our Amazon link even if you're not buying anything right now! :) Thank you all! Sponsors For This Episode: Extreme Health Academy Use code EHR14 for a free 2 week trial! Colostrum (Use Code WERIMMUNE for 20% off until 7/9/2020) Relax FAR Infrared Sauna Chaga Mushroom Bellicon Rebounders Featured Products For This Episode: Blue Blockers Reishi Mushroom Elk Antler Pine Pollen Joovv Red Light Therapy Greenwave Dirty Electricity Filters Aloe Vera Rapid Release Technology Pro 2 Barf World Raw Dog Food The Biomat Chemical Free Organic Skincare! Activation Products - Ocean's Alive & Magnesium Show Notes https://eagle-research.com/product/ac50/ Project 180 Vaccines Show Guest: Tyler LeBaron Guest Info: Masters in Exercise and Sports Conditioning Bachelor of Science in Biochemistry Internship at Nagoya University Japan to research molecular mechanism of H2. Relevant course work include: Biochemistry, Physiology, Advanced Exercise Physiology, Nutritional Biochemistry, Molecular Cell Biology, Quantitative Chemical Analysis, Biology Analysis Techniques Tyler W. LeBaron is the Founder and Executive Director of the science-based nonprofit Molecular Hydrogen Institute. His background is in biochemistry and exercise physiology. He was a 1-year Adjunct Instructor of Physiology, and interned at Nagoya University in the department of Neurogenetics to research the molecular mechanisms of hydrogen gas on cell signaling pathways. He is a director of the International Hydrogen Standards Association (IHSA) and the International Molecular Hydrogen Association (IMHA). He speaks at Medical conferences in the US for doctors CMEs/CEUs, and at academic biomedical hydrogen symposia and conferences around the world. He is also a member of the Academic Committee of Taishan Institute for Hydrogen Biomedical Research.

Dr. Kristen Willeumier is a neuroscientist with an expertise in neuroimaging and psychiatric disorders. She conducted her graduate research in the laboratory of Neurophysiology at UCLA and the laboratory of Neurogenetics at Cedars-Sinai Medical Center. She received M.S. degrees in Physiological science and Neurobiology and a Ph.D. degree in Neurobiology from UCLA. She was a post-doctoral scientist in the Department of Neurology at Cedars-Sinai Medical Center working in the field of neurodegenerative disease. She was the recipient of a fellowship award from the National Institute of Mental Health and has presented her work internationally. Having served as the Director of Neuroimaging Research for the Amen Clinics, she led the efforts in utilizing imaging technologies to better understand the neurobiological issues underlying psychiatric disorders. Dr. Willeumier is widely published in peer-reviewed journals including The Journal of Alzheimer’s Disease, Translational Psychiatry and The Journal of Neuroscience. She is the author of the book Biohack Your Brain: How to Boost Cognitive Health, Proficiency & Power which will be published by the William Morrow imprint of HarperCollins in 2020.

Podcast: Sean Carroll's Mindscape: Science, Society, Philosophy, Culture, Arts, and Ideas (LS 69 · TOP 0.05% what is this?)Episode: 127 | Erich Jarvis on Language, Birds, and PeoplePub date: 2020-12-14Many characteristics go into making human beings special — brain size, opposable thumbs, etc. Surely one of the most important is language, and in particular the ability to learn new sounds and use them for communication. Many other species communicate through sound, but only a very few — humans, elephants, bats, cetaceans, and a handful of bird species — learn new sounds in order to do so. Erich Jarvis has been shedding enormous light on the process of vocal learning, by studying birds and comparing them to humans. He argues that there is a particular mental circuit in the brains of parrots (for example) responsible for vocal learning, and that it corresponds to similar circuits in the human brain. This has implications for the development of intelligence and other important human characteristics.Support Mindscape on Patreon.Erich Jarvis received his Ph.D. in Animal Behavior and Molecular Neurobehavior from Rockefeller University. He is currently a professor in the Laboratory of Neurogenetics of Language at Rockefeller and an investigator at the Howard Hughes Medical Institute. Among his many awards are the Alan T. Waterman Award from the National Science Foundation, an American Philosophical Society Award, a Packard Foundation fellowship, an NIH Director's Pioneer award, Northwestern University's Distinguished Role Model in Science award, and the Summit Award from the American Society for Association Executives.Web siteRockefeller web pageGoogle Scholar publicationsWikipediaTalk on vocal learning and the brainTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.The podcast and artwork embedded on this page are from Sean Carroll | Wondery, which is the property of its owner and not affiliated with or endorsed by Listen Notes, Inc.

Many characteristics go into making human beings special — brain size, opposable thumbs, etc. Surely one of the most important is language, and in particular the ability to learn new sounds and use them for communication. Many other species communicate through sound, but only a very few — humans, elephants, bats, cetaceans, and a handful of bird species — learn new sounds in order to do so. Erich Jarvis has been shedding enormous light on the process of vocal learning, by studying birds and comparing them to humans. He argues that there is a particular mental circuit in the brains of parrots (for example) responsible for vocal learning, and that it corresponds to similar circuits in the human brain. This has implications for the development of intelligence and other important human characteristics.Support Mindscape on Patreon.Erich Jarvis received his Ph.D. in Animal Behavior and Molecular Neurobehavior from Rockefeller University. He is currently a professor in the Laboratory of Neurogenetics of Language at Rockefeller and an investigator at the Howard Hughes Medical Institute. Among his many awards are the Alan T. Waterman Award from the National Science Foundation, an American Philosophical Society Award, a Packard Foundation fellowship, an NIH Director’s Pioneer award, Northwestern University’s Distinguished Role Model in Science award, and the Summit Award from the American Society for Association Executives.Web siteRockefeller web pageGoogle Scholar publicationsWikipediaTalk on vocal learning and the brainTwitter

Join MitoAction and David Keane from GeneDX for our December Monthly Mito Expert Series presentation titled: Mito Genetic Basics: Disease, Testing and Financial. About the Speaker: David Keane has been involved with Neurogenetics since 1998 when he started working for Athena Diagnostics. He has attended over 50 Mitochondrial Disease Grand Rounds Presentations by Dr. Bruce Cohen, Sumit Parikh, Fran Kendall, Amy Goldstein, among others. David was hired by GeneDx in 2011 to help build the Neurogenetics team and currently serves as a Senior Genetic Testing Consultant specializing in Neurology and Mitochondrial Genetics. Accompanying slides can be found by clicking here.

Today's guest runs two and a half hour marathons and deadlifts 450 pounds. He is also one of the smartest guys I've ever met. His name is Tyler LeBaron, and he's the founder and executive director of the science-based nonprofit Molecular Hydrogen Institute. Molecular hydrogen is what's been called the miracle molecule in biohacker circles. It's been credited with preventing everything from radiation damage, hangovers, reducing inflammation, scavenging free radicals, promoting cellular health, increasing physical and mental energy, improving cognitive function, sleep, and even enhancing athletic performance. Tyler is an expert in all things, molecular hydrogen. His background is in biochemistry and he interned at the renowned Japanese Nagoya University in the Department of Neurogenetics to research the molecular mechanisms of hydrogen gas on cell signaling pathways. He's also a director of the International Hydrogen Standards Association, and the International Molecular Hydrogen Association. Tyler speaks at medical conferences all across the world and collaborates with researchers at home and abroad in order to help advance the education research and awareness of hydrogen as a therapeutic medical gas. And I am very excited to go on a deep dive with them about everything molecular hydrogen. In my conversation with Tyler Lebaron, you'll hear: -How Tyler became interested in molecular hydrogen initially...03:33-What does hydrogen do once it's in our bodies?...09:05-The status of hydrogen research in the US...11:26-Molecular hydrogen used to treat rheumatoid arthritis...16:10-Legit benefits of molecular hydrogen or a placebo?...21:08-Positive side effects of molecular hydrogen...27:27-Why you can't rely on breath alone...31:59-Things to watch for when buying molecular hydrogen...36:41-The case for hydrogen as the origin of the universe...41:48-How hydrogen acts as an antioxidant...46:00-The thing that has most profoundly impacted Tyler's human experience...50:14Resources:http://www.molecularhydrogeninstitute.com (Molecular Hydrogen Institute)

Dr. Amy Goldstein provides an update on the Mitochondrial Medicine Society. Areas of discussion include: Transplantation in Mito patients Stroke protocol for MELAS Standards of care for Mito patients Centers of Excellence and the need for community involvement/input About the Speaker Dr. Amy Goldstein, a member of the Board of Trustees of UMDF, is on faculty at Children’s Hospital of Pittsburgh of UPMC in the Division of Pediatric Neurology. She is board certified in pediatrics, neurology, and psychiatry with Special Qualifications in Child Neurology. She is currently an Assistant Professor at the University of Pittsburgh School of Medicine. She began a multidisciplinary Mitochondrial Disease clinic in 2007 and is now the Director of Neurogenetics & Metabolism and the site Principle Investigator for NAMDC (the North American Mitochondrial Disease Consortium). She is also President of the Mitochondrial Medicine Society. Her clinical research interests include improving fatigue and exercise intolerance as well as developing common patient-centered outcome measures for clinical trials. To view the accompanying slides, click here.

There is a growing sense that the one certainty we can count on over the coming weeks, months, and years, is uncertainty. From the ancient stoics and philosophers to contemporary historians, writers and economists, thinkers have grappled with this concept and its implications. What can they tell us about our current predicament, and can we learn to tolerate uncertainty in our daily lives? In our forthcoming Behind the Headlines, we explore what uncertainty means today. In the midst of a global pandemic, with looming lockdowns, an unsettled political climate, economic volatility and the spectre of false news, we will consider possible responses to life in the ‘age of uncertainty' and discuss the ways in which unpredictability shapes our feelings about the future. Speakers: Professor Siobhán Garrigan, Loyola Chair of Theology, Head of School of Religion, TCD, will look at how Christianity offers a wealth of resources on how to cope with uncertainty … as well as quite a few examples of how not to cope with it. Professor Kenneth Pearce, Ussher Assistant Professor in Berkeley Studies, Head of Department of Philosophy, TCD, will explore early modern traditions of philosophy and their approach to uncertainty, asking if making peace with uncertainty is essential for life in the modern world. Professor Mani Ramaswami, Professor of Neurogenetics, Director of Trinity Institute of Neurosciences (TCIN), will examine uncertainty from the perspective of Neuroscience, looking at our brain's ability to accurately predict the future, and how we can use uncertainty to our advantage. Carmel Crimmins, Financial Desk Deputy Editor, Reuters, will look at how we produce the news during a global pandemic with societies under lockdown, rumour and misinformation proliferating online and stories breaking on multiple fronts.

Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2020.06.09.142471v1?rss=1 Authors: Floris, D. L., Filho, J. O. A., Lai, M.-C., Giavasis, S., Oldehinkel, M., Mennes, M., Charman, T., Tillmann, J., Dumas, G., Ecker, C., Dell'Acqua, F., Banaschewski, T., Moessnang, C., Baron-Cohen, S., Durston, S., Loth, E., Murphy, D. G., Buitelaar, J. K., Beckmann, C., Milham, M., Di Martino, A. Abstract: Background: Marked sex differences in autism prevalence accentuate the need to understand the role of biological sex-related factors in autism. Efforts to unravel sex differences in the brain organization of autism have, however, been challenged by the limited availability of female data. Methods: We addressed this gap by using the largest sample of male and female autistic and neurotypical (NT) control individuals, to date (ABIDE; Autism: 362 males, 82 females; NT: 410 males, 166 females; 7-18 years). Discovery analyses examined main effects of diagnosis, sex and their interaction across five resting-state fMRI (R-fMRI) metrics. Secondary analyses assessed the robustness of primary results to different pre-processing approaches and their replicability in two independent samples, the EU-AIMS Longitudinal European Autism Project (LEAP) and the Gender Explorations of Neurogenetics and Development to Advance Autism Research (GENDAAR). Results: Discovery analyses in ABIDE revealed significant main effects across the intrinsic functional connectivity (iFC) of the posterior cingulate cortex, regional homogeneity and voxel-mirrored homotopic connectivity (VMHC) in several cortical and subcortical regions. Sex-by-diagnosis interactions were confined to VMHC in dorsolateral occipital cortex with reduced VMHC in females with autism. Findings were highly robust to different pre-processing steps and replicable in another sample. Specifically, the sex-by-diagnosis interaction replicated in the larger of the two replication samples - EU-AIMS LEAP. Conclusions: Results emphasize that atypical cross-hemispheric interactions are neurobiologically relevant to autism. Systematic assessments of the factors contributing to their replicability are needed and necessitate coordinated large-scale data collection across studies. Copy rights belong to original authors. Visit the link for more info

There’s something that you’re going to get to know about me pretty fast listening to this show:  water and hydrogen EXCITE ME! Weird? Maybe. But we could all benefit from learning a little bit more about hydrogen. Hydrogen is one of the BEST immune modulators. As we know, all disease is related to inflammation and modulating inflammation is essential for thriving in this modern world.  Today, we’re talking to someone who is trying to change that, and who can teach us what we DO know about the clinical benefits of molecular hydrogen: Tyler W. LeBaron, the Founder and Executive Director of the Molecular Hydrogen Institute (MHI), a science-based nonprofit focused on advancing the research, education, and awareness of hydrogen as a potential therapeutic medical gas. Tyler was a 1-year Adjunct Instructor of Physiology, and interned at Nagoya University in the department of Neurogenetics to research the molecular mechanisms of hydrogen gas on cell signaling pathways. He is a director of the International Hydrogen Standards Association (IHSA) and the International Molecular Hydrogen Association (IMHA). He speaks at Medical conferences in the US for doctors CMEs/CEUs, and at academic biomedical hydrogen symposia and conferences around the world. He is also a member of the Academic Committee of Taishan Institute for Hydrogen Biomedical Research. He collaborates with researchers at home and abroad, and helps advance the education, research, and awareness of hydrogen as a therapeutic medical gas. Which is really just a long way of saying that Tyler might actually be MORE obsessed with hydrogen than I am! And he just has so much education and insight to share about how molecular hydrogen interacts with our bodies and how we can start taking advantage of molecular hydrogen to regulate inflammation, minimize oxidation, and facilitate hydration. Resources: Want the best hydration and recovery drink? Use code “TracyDuhs” for 10% off H2Bev drinks at h2bev.com Molecular Hydrogen Institute   Connect with Tyler W. LeBaron: WEBSITE | www.molecularhydrogeninstitute.com INSTAGRAM | https://www.instagram.com/tylerwlebaron   Connect with Tracy Duhs: WEBSITE | www.tracyduhs.com INSTAGRAM | www.instagram.com/tracyduhs FACEBOOK | www.facebook.com/tduhs   Hydrate is a production of Operation Podcast

Elizabeth Fisher, Professor of Neurogenetics at University College London, spent 13 years getting her idea – finding a new way of studying genetic disorders – to work. She began her research career at a time, in the 1980s, when there was an explosion of interest and effort in finding out what genes did what, and which of them were responsible for giving rise to the symptoms of various neurodegenerative conditions. Elizabeth has been particularly interested in those in which there are chromosomal abnormalities, like Down syndrome and Turner syndrome, as distinct from specific genetic disorders. Her work has helped in the understanding of what’s different about the genetic make-up of people with these conditions, and what new therapies might be developed in the future. Lizzie Fisher talks to Jim al-Khalili about how she was inspired to study genetics while standing on the red carpet, how she kept going during the 13 years it took to introduce human chromosomes into mice and why she's starting the process all over again.

Elizabeth Fisher, Professor of Neurogenetics at University College London, spent 13 years getting her idea – finding a new way of studying genetic disorders – to work. She began her research career at a time, in the 1980s, when there was an explosion of interest and effort in finding out what genes did what, and which of them were responsible for giving rise to the symptoms of various neurodegenerative conditions. Elizabeth has been particularly interested in those in which there are chromosomal abnormalities, like Down syndrome and Turner syndrome, as distinct from specific genetic disorders. Her work has helped in the understanding of what's different about the genetic make-up of people with these conditions, and what new therapies might be developed in the future. Lizzie Fisher talks to Jim al-Khalili about how she was inspired to study genetics while standing on the red carpet, how she kept going during the 13 years it took to introduce human chromosomes into mice and why she's starting the process all over again.

Dr. Scholz is a neurologist and neurogeneticist specialized in movement disorders. She received her medical degree from the Medical University Innsbruck, Austria. Following graduation, she was a post-doctoral fellow at the National Institutes of Health under Drs. Andrew Singleton and John Hardy. She obtained a Ph.D. in neurogenomics from the University College London, UK in 2010. She then moved to complete her neurology residency at Johns Hopkins. In 2015, Dr. Scholz received the McFarland Transition to Independence award for Neurologist-Scientists. She is an assistant clinical investigator at the National Institute of Neurological Disorders and Stroke (NIND). Her lab focuses on identifying genetic causes of neurodegenerative diseases, such as dementia with Lewy bodies, multiple system atrophies, and frontotemporal dementia.

Shenela Lakhani is the Director of Genetic Counseling and Clinical Engagement for the Center of Neurogenetics at Weill Cornell Medical College, in New York City. In this role she studies the genetics of neurodevelopmental disorders and neurological disease of aging and adulthood.Before this role, she was the first certified genetic counselor in Qatar, a country in the Middle East. Shenela established the profession in the country and promoted genetics within the Middle East by speaking at international conferences. In Qatar she helped to establish high-risk breast cancer screening guidelines and a high-risk gastrointestinal clinic while contributing to local testing and screening guidelines.On this episode we explore what it was like to be the first certified genetic counselor in a country and how she was able to start the profession there and make an impact in public health in Qatar.On This Episode We Discuss:Inspiration and Motivation to Move Across the WorldChallenges of Starting Genetic Counseling in A New CountryCommon Genetic Disorders in QatarGenetic Stigma and Public Perspective of HealthcareGenetic Carrier and Newborn Testing in QatarAdaptations to Counseling in A Different CountryLearn more about Shenela Lakhani on her LinkedIn Profile and Weill Cornell’s Center for Neurogenetics website.Stay tuned for the next new episode of DNA Today on October 24th, 2019. In this special installment my peers Ale Cantu and Catherine Mayo join me to celebrate the 22nd anniversary of the genetics film Gattaca by discussing its relevance today in the field.New episodes are released on the first and third Fridays of the month. See what else we are up to on Twitter, Instagram, Facebook and iTunes. Questions/inquiries can be sent to info@DNApodcast.com.

In this "in-between-isode" of Anamnesis, MedPage reporter Elizabeth Hlavinka shares highlights presented at AAN 2019, the annual meeting of The American Academy of Neurology. PHILADELPHIA -- Learn why AAN 2019, was 'The Year of NMO', neuromyelitis optica spectrum disorder. Episode produced by Elizabeth Hlavinka Hosted and sound engineering by Greg Laub Music by Jason Asistores, MD aka flatfives.

In this episode, I sit down with Tyler W. LeBaron, Founder and Executive Director of the science-based nonprofit Molecular Hydrogen Institute. His background is in biochemistry and exercise physiology. He was a 1-year Adjunct Instructor of Physiology, and interned at Nagoya University in the department of Neurogenetics to research the molecular mechanisms of hydrogen gas on cell signaling pathways. He is a director of the International Hydrogen Standards Association (IHSA) and the International Molecular Hydrogen Association (IMHA). He speaks at Medical conferences in the US for doctors CMEs/CEUs, and at academic biomedical hydrogen symposia and conferences around the world. He is also a member of the Academic Committee of Taishan Institute for Hydrogen Biomedical Research. He collaborates with researchers at home and abroad, and helps advance the education, research, and awareness of hydrogen as a therapeutic medical gas. Tyler and I dive deep into the science behind how molecular hydrogen works in the body, and how you can use it to optimize your workouts and overall health. To see the full show notes, please visit http://blog.biohackingsecrets.com. Here's where you can grab your copy of our free book The Biohacker's Guide to Upgraded Energy and Focus (just help with shipping) https://biohackersguide.com/biohackers-guide-free. Learn more about the #1 High Performance Coaching Program in the world and have Anthony personally help you get in the best shape of your life, double your energy, and live in a state of optimal performance www.biohackingsecrets.com/coaching

1. The ethical and philosophical implications of gene editing. 2. [What’s Trending]: Scientific and societal impact gene editing , Dr. Jason Crowell talks with Dr. Josephine Johnston of the Hastings Center on the ethical and philosophical implications of gene editing. In the second part of the podcast, Dr. Stacey Clardy focuses her interview with Dr. Stefan Pulst on the scientific and societal impact of the recent first reported gene editing using the CRISPR technology. Dr. Jason Crowell reports no disclosures. Dr. Josephine M. Johnston has received honoraria for speaking or travel from The Hastings Center, the University of Toronto, Danbury Hospital, World Science festival, the Yale School of Medicine, the University of Pennsylvania Law School, the Royal Society of New Zealand, McGill University, Dalhousie University, and Queensland University of Technology; and has received foundation/society research support from the John Templeton Foundation. Dr. Clardy serves as the Podcast Section Editor for Neurology and has received research support from Western Institute for Biomedical Research (WIBR). Dr. Stefan Pulst has served on the editorial boards of Journal of Cerebellum, NeuroMolecular Medicine, Experimental Neurology, Neurogenetics, Nature Clinical Practice, Neurology, and as the Editor-in-Chief of Neurology: Genetics; holds numerous patents (for the following: Nucleic acids encoding ataxin-2 binding proteins; Nucleic acid encoding Schwannomin-binding-proteins and products related thereto; Transgenic mouse expressing a polynucleotide encoding a human ataxin-2 polypeptide; Methods of detecting spinocerebellar ataxia-2 nucleic acids; Nucleic acid encoding spinocerebellar ataxia-2 and products related thereto; Shwannomin-binding-proteins; Compositions and methods for spinocerebellar ataxia); has received publishing royalties from The Ataxias (Churchill Livingston, 2007), Genetics in Neurology (ANN Press, 2005), Genetics of Movement Disorders (Academic Press, 2003), Neurogenetics (Oxford University Press, 2000), Molecular Genetic Testing in Neurology, 2nd - 5th (AAN Press, 1996); has served as a consultant for Ataxion Therapeutics; has served on the speakers' bureau for Athena Diagnostics, Inc.; has received governmental research support from National Institutes of Health and the Clinical Research Consortium for Spincerebellar Ataxias; has received foundation/society research support for serving as a fellowship award mentor from National Ataxia Foundation; and has received license fee payments for technology or inventions from the Cedars-Sinai Medical Center.

Being a parent is often a balancing act of comfort and discipline. According to a recent study lead by researches from the University of Pennsylvania, the University of Michigan, and Michigan State University, the environment parents created at home can have a lasting impact on their kids, and if that home life is harsh it can lead to antisocial behavior in children. Host Dan Loney speaks with Rebecca Waller, Lead author of this study and Assistant Professor of Psychology at Penn, about the results of this study on Knowledge@Wharton. Rebecca is also the Director of Penn's EDEN Lab (Emotion, Development, Environment, & Neurogenetics). See acast.com/privacy for privacy and opt-out information.

Join us for a real, raw and powerful conversation that calls on all of us to do our part in removing the shame and stigma surrounding mental illness. In the United States, anxiety disorders are the most common mental illness, affecting over 40MM adults -- over 18% of the U.S. population. It's the leading cause of disability, judged by years lost to disease, yet only a small percentage of people with the illness receive treatment.  In the latest episode of Spit, host Baratunde Thurston discusses mental health with a trio of folks who are working every day to combat the stigma, using their expertise, their research and their platform to make a difference. In part one of this episode, Baratunde sits down with singer, songwriter and mental health advocate Mike Shinoda and Dr. Gail Saltz, Clinical Associate Professor of Psychiatry at the New York Presbyterian Hospital, Weill-Cornell Medical College and a psychoanalyst with the New York Psychoanalytic Institute. Together they explore what mental illness is; how genetics and your environment together play a factor in triggering anxiety disorders; the importance of checking in with yourself and with those around you; and how we can all foster and create safe and positive spaces at home, at work and in the world. Mike speaks openly about his journey since losing best friend and Linkin Park bandmate Chester Bennington, asking Dr. Saltz, “Is there more we can do? And if so, how?” He also explores the notion that artists create from a place of “genius” and if that genius can ultimately lead to crippling pressures and self-doubt, further increasing the risk of depression and substance use. In part two, we get a deeper understanding of the genetic science behind mental health and the latest research about the brain's role in mental wellness when Baratunde speaks with Dr. Ahmad Hariri, a Professor of Psychology & Neuroscience at Duke University, where he is also the Director of the Laboratory of NeuroGenetics. Dr. Hariri is the author of Looking Inside the Disordered Brain. https://bit.ly/2ySrMa0 Spit is an iHeartRadio podcast with 23andMe. Enjoy this episode and subscribe, rate and review Spit on Apple Podcasts. And be sure to tell your friends all about it. Find out more about our host Baratunde Thurston at Baratunde.com or sign up for his text messages at 202-902-7949. 

On this episode, Tyler LeBaron of the Molecular Hydrogen Institute (MHI) comes on the show to talk about molecular hydrogen and how it can supplement the body for anti-aging and performance. They discuss some of the promise that drinking hydrogen-rich water is showing for Parkinson’s patients and in other brain injury therapies. They consider how the intake of molecular hydrogen aids in ATP production and mitochondrial function. Free radicals can cause damage to your cells, and molecular hydrogen can act as a signaling molecule to upregulate your body to better manage oxidative stress. Our body needs oxidative power and reductive power in balance, and molecular hydrogen can help bring you back to homeostasis.   Hydrogen also helps modulates the system that causes inflammation, which is a major cause of aging. LeBaron suggests how and when to get hydrogen into your system and offers some warnings about products on the market. Dr. Gladden talks about some of the ways he uses molecular hydrogen with his patients at Apex.   They also discuss the benefits of being in a “flow state” in your life, during work or working out. Special Guest: Tyler W. LeBaron is the Founder and Executive Director of the science-based nonprofit Molecular Hydrogen Institute. His background is in biochemistry and was a 1-year Adjunct Instructor of Physiology. He Interned at Nagoya University in the department of Neurogenetics to research the molecular mechanisms of hydrogen gas on cell signaling pathways. He is a director of the International Hydrogen Standards Association (IHSA) and the International Molecular Hydrogen Association (IMHA). He speaks at Medical conferences in the US for doctors CMEs/CEUs, and at academic biomedical hydrogen symposia and conferences around the world. He is also a member of the Academic Committee of Taishan Institute for Hydrogen Biomedical Research. He collaborates with researchers at home and abroad, and helps advance the education, research, and awareness of hydrogen as a therapeutic medical gas. Learn more at the Molecular Hydrogen Institute. Follow LeBaron on Facebook.

Sources: Klimecki, O.M., Leiberg, S., Ricard, M., and Singer, T. (2013) Differential pattern of functional brain plasticity after compassion and empathy training. Social Cognitive and Affective Neuroscience. doi:10.1093/scan/nst060. Layous, K. S., Nelson K., Kurtz J.L., and Lyubomirsky S. (2017). What triggers prosocial effort? A positive feedback loop between positive activities, kindness, and well-being. The Journal of Positive Psychology 12(4), 385-398. Nelson, S.K, Cole, S.W., Layous, K. and Lyubomirsky S. (2016). Do Unto Others or Treat Yourself? The Effects of Prosocial and Self-Focused Behavior on Psychological Flourishing. Emotion 16(6), 850–861. Piper, W.T., Saslow, L.R., and Saturn, S.R. (2015). Autonomic and prefrontal events during moral elevation. Biological Psychology 108, 51–55. Poulin, M.J., Holman, E.A., and Buffone A. (2012). The Neurogenetics of Nice: Receptor Genes for Oxytocin and Vasopressin Interact With Threat to Predict Prosocial Behavior. Psychological Science 23(5), 446–452.

Tyler LeBaron - Part 2 of 2 Tyler W. LeBaron is the Founder and Executive Director of the science-based nonprofit Molecular Hydrogen Foundation/Institute. His background is in biochemistry and was a 1-year Adjunct Instructor of Physiology. He Interned at Nagoya University in the department of Neurogenetics to research the molecular mechanisms of hydrogen gas on cell signaling pathways. He is a director of the International Hydrogen Standards Association (IHSA) and the International Molecular Hydrogen Association (IMHA). He speaks at Medical conferences in the US for doctors CMEs/CEUs, and at academic biomedical hydrogen symposia and conferences around the world. He is also a member of the Academic Committee of Taishan Institute for Hydrogen Biomedical Research. He collaborates with researchers at home and abroad, and helps advance the education, research, and awareness of hydrogen as a therapeutic medical gas. Molecular hydrogen (H2) or diatomic hydrogen is a tasteless, odorless, flammable gas. Over 500 peer-reviewed articles demonstrate hydrogen to have therapeutic potential in essentially every organ of the human body and in 150 different human disease models. H2 reduces oxidative stress as a selective antioxidant and by maintaining homeostatic levels of glutathione, superoxide dismutase, catalase, etc. H2, like other gaseous signaling molecules (i.e. NO, CO, H2S), appears to have cell signal-modulating activity affording it with anti-inflammatory, anti-obesity, and anti-allergy benefits. Key Molecular Hydrogen Related links mentioned in the podcast: Nature Medicine:https://www.nature.com/articles/nm1577 Hyperbaric hydrogen:https://www.ncbi.nlm.nih.gov/pubmed/1166304 Overview on H2:http://www.molecularhydrogeninstitute.com/hydrogen-an-emerging-medical-gas alkaline water ionizers: http://www.molecularhydrogeninstitute.com/mildly-alkaline-ionized-water-characteristics-benefits-and-future Connect with Tyler here https://www.facebook.com/H2MHF Molecular Hydrogen Related Products. Inhalation:https://www.californiahydrogenwater.com/store/c1/Featured_Products.html Tablets:https://drinkhrw.com/base/home RTD:https://h2bev.com Machines: https://www.trusiih2.com/biohacks Rate, Review, Connect, Inspire Stay updated on new episodes, guest interviews, and health, wellness, and fitness information and resources by subscribing to the HealthCastNow Podcast Show on iTunes. Every day we bring you actionable insight, demystified truth, and simple steps to help you navigate the complex, often confusing health, wellness, and fitness information and answer the questions you’ve been asking Visit HealthCastNow.Com or subscribe on iTunes today!

Tyler LeBaron - Part 1 of 2 Tyler W. LeBaron is the Founder and Executive Director of the science-based nonprofit Molecular Hydrogen Foundation/Institute. His background is in biochemistry and was a 1-year Adjunct Instructor of Physiology. He Interned at Nagoya University in the department of Neurogenetics to research the molecular mechanisms of hydrogen gas on cell signaling pathways. He is a director of the International Hydrogen Standards Association (IHSA) and the International Molecular Hydrogen Association (IMHA). He speaks at Medical conferences in the US for doctors CMEs/CEUs, and at academic biomedical hydrogen symposia and conferences around the world. He is also a member of the Academic Committee of Taishan Institute for Hydrogen Biomedical Research. He collaborates with researchers at home and abroad, and helps advance the education, research, and awareness of hydrogen as a therapeutic medical gas. Molecular hydrogen (H2) or diatomic hydrogen is a tasteless, odorless, flammable gas. Over 500 peer-reviewed articles demonstrate hydrogen to have therapeutic potential in essentially every organ of the human body and in 150 different human disease models. H2 reduces oxidative stress as a selective antioxidant and by maintaining homeostatic levels of glutathione, superoxide dismutase, catalase, etc. H2, like other gaseous signaling molecules (i.e. NO, CO, H2S), appears to have cell signal-modulating activity affording it with anti-inflammatory, anti-obesity, and anti-allergy benefits. Key Molecular Hydrogen Related links mentioned in the podcast: Nature Medicine:https://www.nature.com/articles/nm1577 Hyperbaric hydrogen:https://www.ncbi.nlm.nih.gov/pubmed/1166304 Overview on H2:http://www.molecularhydrogeninstitute.com/hydrogen-an-emerging-medical-gas alkaline water ionizers: http://www.molecularhydrogeninstitute.com/mildly-alkaline-ionized-water-characteristics-benefits-and-future Connect with Tyler here https://www.facebook.com/H2MHF Molecular Hydrogen Related Products. Inhalation:https://www.californiahydrogenwater.com/store/c1/Featured_Products.html Tablets:https://drinkhrw.com/base/home RTD:https://h2bev.com Machines: https://www.trusiih2.com/biohacks Rate, Review, Connect, Inspire Stay updated on new episodes, guest interviews, and health, wellness, and fitness information and resources by subscribing to the HealthCastNow Podcast Show on iTunes. Every day we bring you actionable insight, demystified truth, and simple steps to help you navigate the complex, often confusing health, wellness, and fitness information and answer the questions you’ve been asking Visit HealthCastNow.Com or subscribe on iTunes today!

Today Dr. Susan Buttross welcomes in an esteemed guest. He's Dr. Pat Levitt, Director of The Developmental Neurogenetics, Professor of Pediatrics and W.M. Keck Chair in Neurogenetics at the Keck School of Medicine at the University of Southern California. See acast.com/privacy for privacy and opt-out information.

My guest on today's podcast is an absolute phenom and was first introduced to me by Dr. Joseph Mercola, one of the most popular guys I've ever had on my podcast He's just 30 years old. He has run a 2:30 marathon and can deadlift 450 pounds. And he's one smart cookie. His name is Tyler LeBaron, and he is the Founder and Executive Director of the science-based nonprofit . His background is in biochemistry, he interned at Nagoya University in the department of Neurogenetics to research the molecular mechanisms of hydrogen gas on cell signaling pathways, he is a director of the International Hydrogen Standards Association (IHSA) and the International Molecular Hydrogen Association (IMHA), he speaks at Medical conferences across the USA for physicians, and at academic biomedical hydrogen symposia and conferences around the world. He is also a member of the Academic Committee of Taishan Institute for Hydrogen Biomedical Research. He collaborates with researchers at home and abroad, and helps advance the education, research, and awareness of hydrogen as a therapeutic medical gas. He has a Bachelor's degree in Biochemistry, and has studied Physiology, Advanced Exercise Physiology, Nutritional Biochemistry, Molecular Cell Biology, Quantitative Chemical Analysis, Biology Analysis Techniques. His research spans the gamut and includes: -Therapeutic effects of hydrogen gas -Free Radical Biology and Medicine -Therapeutic effects of electrolyzed reduced water -Therapeutic effects of exercise for disease prevention and treatment -Biological effects of inorganic nitrates -Biological and chemical properties of creatine -Vitamins, minerals and nutraceuticals -Supplements and ergogenic aids -Health, longevity and wellness -Physiology, biochemistry and organic chemistry During our discussion, you'll discover: -What Tyler's training looks like to be able to lift heavy and also run as fast as you run in an endurance sport... -Whether Tyler follows any special diet or takes any special supplements... -How hydrogenated water is far different than regular water... -The way that hydrogen gas dissolved in water actually affects your cells... -Whether hydrogenated water blunts the hormetic response to exercise and why it may be one of the few antioxidants one could potentially use in conjunction with hard exercise... -How hydrogenated water can act as an exercise mimetic, just like "exercise in a pill"... -The effects of hydrogenated water on exercise performance and also on digestive health... -The fascinating anti-allergenic and anti-exercise-induced asthma effects of hydrogenated water... -Why most people haven't heard of molecular hydrogen... -The link between molecular hydrogen and so-called "healing waters"... -How much hydrogen water you actually need to drink to get the benefits... -Where can people get molecular hydrogen? (if there is any kind of affiliate link or discount code we can use for my audience, let me know!) Resources from this episode: - - (use code BEN for 10% discount) - - use code Greenfield to get a free promo package with your first purchase of the tablets, including a 'to go' stainless steel double walled gasketed vacuum bottle, a branded phone back ring and a branded USB, value $30! - Show Sponsors:  -MVMT Watches -  Get 15% off today —WITH FREE SHIPPING and FREE RETURNS—by going to -Peleton -  Discover this cutting-edge indoor cycling bike that brings the studio experience to your home. Peloton is offering listeners a limited-time offer…Go to , enter the code "GREENFIELD" at checkout, and get $100 off accessories with your Peloton bike purchase.  -Omax - Go to today to get a box of Omax3 Ultra-Pure, FOR FREE! Terms and conditions apply. -Onnit - Go to and save 10% on your purchase. The discount is built into the link. Do you have questions, thoughts or feedback for Tyler or me? Leave your comments at

Interviews on neurological topics related to genetics

This is the second of a two part conversation with Elissa Chesler and Steve Munger. We continue to talk about the science of drug addiction and discuss the new Center for Systems Neurogenetics of Addiction. We also discuss Elissa's other interest, which include Legos, astronomy, country living and more.

For this "rescued" episode, Steve Munger makes his return, joining Dave for a discussion with JAX Associate Professor Elissa Chesler. We talk about Elissa’s systems genetics approach for studying complex behaviors and why she is using this approach to study the neurogenetics of addiction. This episode is part 1 of a 2-part series.

1) Aerobic training and post-exercise protein in facioscapulohumeral muscular dystrophy and 2) Topic of the month: Plenary sessions AAN Meeting April 2015. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Erik Ensrud interviews Dr. Grete Andersen about her paper on aerobic training and post-exercise protein in facioscapulohumeral muscular dystrophy. Dr. Adam Numis is reading our e-Pearl of the week about non-invasive imaging of arterial dissection with MRI. In the next part of the podcast Dr. Alberto Espay interviews Dr. Stefan Pulst about his George C. Cotzias Lecture at the AAN Meeting about the topic of degenerative ataxias: From genes to therapies. The participants had nothing to disclose except Drs. Ensrud, Numis, Espay and Pulst.Dr. Ensrud serves on the data safety monitoring board for phase II trial of methotrexate in myastenia gravis; is a consultant for Skulpt/Convergence Medical Devices and FDA; received honoraria and funding for travel from Osler Institute; received funding for travel from American Association of Physical Medicine and Rehabilitation; and received honoraria from American Association of Neuromuscular and Electrodiagnostic Medicine.Dr. Numis serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Espay serves as an Associate Editor of Movement Disorders, Frontiers in Movement Disorders and Journal of Clinical Movement Disorders; serves as an editorial board member of Parkinsonism and Related Disorders and The European Neurological Journal; receives royalties for publications of books from Lippincott, Williams & Wilkins and from Cambridge University Press; serves on the scientific advisory board for Solvay Pharmaceuticals, Inc. (now Abbvie), Chelsea Therapeutics, Teva Pharmaceutical Industries Ltd., Impax Pharmaceuticals, Merz, Pfizer Inc, Solstice Neurosciences, LLC, Eli Lilly and Company, US WorldMeds; is a consultant for Chelsea Therapeutics, Solvay Pharmaceuticals, Inc. (now Abbvie); serves on the speakers' bureaus of UCB, Teva Pharmaceutical Industries Ltd., American Academy of Neurology, Movement Disorders Society; receives research support from CleveMed/Great Lakes Neurotechnologies, Michael J. Fox Foundation and the NIH.Dr. Pulst serves as Editor-in-Chief of Current Genomics; serves as Editor of Neurology® Genetics; serves as an editorial board member of Journal of Cerebellum, NeuroMolecular Medicine, Continuum, Experimental Neurology, Neurogenetics, and Nature Clinical Practice Neurology; is author on patents re: Nucleic acids encoding ataxin-2 binding proteins; Nucleic acid encoding Schwannomin-binding-proteins and products related thereto; Transgenic mouse expressing a polynucleotide encoding a human ataxin-2 polypeptide; Methods of detecting spinocerebellar ataxia-2 nucleic acids; Nucleic acid encoding spinocerebellar ataxia-2 and products related thereto; Schwannomin-binding-proteins; and Compositions and methods for spinocerebellar ataxia; receives royalties from the publications of the books The Ataxias, Genetics in Neurology, Genetics of Movement Disorders, Neurogenetics, and Molecular Genetic Testing in Neurology, 2nd–5th ed.; serves on the speakers' bureau for Athena Diagnostics; receives research support from the NIH and the National Ataxia Foundation; receives license fee payments from Cedars-Sinai Medical Center; and has provided expert testimony in a medico-legal case.

The development of psychopathology occurs through the complex interplay of genes, experience, and the brain.  In this talk, I will describe a developmental neurogenetics approach to understanding the development of psychopathology.  In this approach, individual variability in genetic background is linked to neural function and subsequent risk and resilience through interactions with the environment. Guided by a developmental psychopathology framework, I will give examples of approaches to link genes, brain, behavior, and experience, with a particular emphasis on studies from my lab aimed at understanding the development of antisocial behavior (e.g., aggression, theft, and violation of serious rules). These examples highlight the role of serotonin genes on amygdala reactivity, the role of amygdala reactivity in antisocial behavior, and the importance of identifying subtypes of antisocial behavior such as callous-unemotional traits and psychopathy that may have different etiologies. September 24, 2014


Dr. Joel Levine is an Associate Professor of Biology and the Canada Research Chair in Neurogenetics at the University of Toronto, Mississauga. He received his PhD in Dr. Richard Miselis Anatomy and Structural Biology from the University of Pennsylvania. He then completed a Postdoctoral Fellowship with Rob Jackson at the Worcester Foundation for Biological Research, a postdoc fellowship with Dr. Steven Reppert at Harvard University, and a postdoc with Dr. Jeffrey Hall at Brandeis University before joining the faculty at the University of Toronto. Joel is here with us today to tell us all about his journey through life and science.

The development of psychopathology occurs through the complex interplay of genes, experience, and the brain.  In this talk, I will describe a developmental neurogenetics approach to understanding the development of psychopathology.  In this approach, individual variability in genetic background is linked to neural function and subsequent risk and resilience through interactions with the environment. Guided by a developmental psychopathology framework, I will give examples of approaches to link genes, brain, behavior, and experience, with a particular emphasis on studies from my lab aimed at understanding the development of antisocial behavior (e.g., aggression, theft, and violation of serious rules). These examples highlight the role of serotonin genes on amygdala reactivity, the role of amygdala reactivity in antisocial behavior, and the importance of identifying subtypes of antisocial behavior such as callous-unemotional traits and psychopathy that may have different etiologies. September 24, 2014


Dr. Marla Sokolowski is a University Professor in the Departments of Ecology and Evolutionary Biology  as well as Canada Research Chair in Genetics and Behavioral Neurology at the University of Toronto. She is also Academic Director of the University of Toronto Fraser Mustard Institute for Human Development and Co-Director of the Child & Brain Development Programme of the Canadian Institute for Advanced Research where she is the Weston Fellow. She received her PhD in Zoology from the University of Toronto and served on the faculty at York University before joining the faculty at the University of Toronto. Marla has received many awards and honors during her career. She is a Fellow of the Royal Society of Canada and Senior Fellow at Canadian Institute for Advanced Research. She has also received the Genetics Society of Canada's Award of Excellence, the Queen Elizabeth Diamond Jubilee Medal, and the Award of Excellence from the International Society of Behavior and Neurogenetics. Marla is with us today to tell us all about her journey through life and science.

Stuart Pickering-Brown, Professor of Neurogenetics and MRC Senior Research Fellow, Institute of Brain, Behaviour and Mental Health, University of Manchester, Manchester - UK speaks on "Cellular modeling of the C9orf72 repeat expansion - RNA Metabolism: Changing Paradigms in Neurodegeneration” This seminar has been recorded at Area Science Park Trieste by ICGEB Trieste

Açık Bilim Cepyayını'nda bu ayki konuğumuz Prof. Dr. Aslıhan Tolun. Prof. Dr. Aslıhan Tolun Prof. Dr. Tolun, 1982’den bu yana Boğaziçi Üniversitesi Moleküler Biyoloji ve Genetik Bölümü’nde araştırmalarını sürdürüyor. 1984 yılında TÜBİTAK teşvik ödülünü kazanan Tolun, daha önce Türkiye Bilimler Akademisi üyesiyken 2011 Aralığından bu yana Bilim Akademisi üyesi. Kendisine söyleşi için yeniden teşekkür ederiz. Notlar Bu yayında odaklandığımız bilimsel makale: A. Guven vd., 2012. Novel NDE1 homozygous mutation resulting in microhydranencephaly and not microlyssencephaly. Neurogenetics 13:189–194. Bu eile üzerinde Aslıhan Tolun grubunun daha önceki iki yayını: G. N. Kavaslar vd., 2000. The Novel Genetic Disorder Microhydranencephaly Maps to Chromosome 16p13.3-12.1. American Journal of Human Genetics 66:1705-1709. ve J. Behunova vd., 2010. Familial microhydranencephaly, a family that does not map to 16p13.13-p12.2: relationship with hereditary fetal brain degeneration and fetal brain disruption sequence. Clinical Dysmorphology 19:107-118. Hocanın daha önce Cumhuriyet Bilim Teknoloji dergisinde benzeri konudaki söyleşisi. Bahsi geçen ve insan genleriyle fenotiplerin ilişkilendirildiği OMIM veritabanı. Mutasyonlar ve etkileri konusunda daha önce yazdığım bir yazıyı öneriyorum. Kendi sesimin kaydındaki bozukluk için özür dilerim.

Hear how human genetics is transforming neuroscience (0:55),  understand how sphingolipids are key signaling molecules during development(16:34), and learn about a critical interaction in noncanonical Wnt signaling (25:34). 

A surgeon treats a patient with almost no chance of recovery. Dr. Murat Gunel is the Chief and Neurovascular Surgery Program Co-director, at the Yale Program on Neurogenetics at the Yale School of Medicine. To learn more about listener data and our privacy practices visit: https://www.audacyinc.com/privacy-policy Learn more about your ad choices. Visit https://podcastchoices.com/adchoices