Metabolic Mind

Are we turning to ADHD and depression medications too quickly for kids?The Wall Street Journal and New York Times recently published powerful investigations into the overuse of psychiatric medications in children. In this video, Dr. Bret Scher unpacks the key takeaways, the risks of polypharmacy, and why a comprehensive, root-cause approach is more important than ever for kids facing mental health challenges.

If you carry the ApoE4 gene, you've likely been told your risk for Alzheimer's disease is significantly higher. But what does that really mean, and how much control do you actually have?In this video, Dr. Bret Scher breaks down the science behind ApoE4, one of the strongest genetic risk factors for Alzheimer's disease, and explains why increased risk does not mean a predetermined outcome.You'll learn how ApoE4 may influence brain health through inflammation, lipid metabolism, and energy use, and why lifestyle and environment play a critical role in shaping these pathways.This video also explores:Why ApoE4 does not guarantee Alzheimer's diseaseWhat research shows about traditional populations with low dementia ratesHow metabolic health, diet, and lifestyle may influence brain agingNew research challenging common assumptions about meat, fat, and dementia riskThe role of key nutrients like B12, iron, and amino acids in brain functionDr. Scher also reviews recent observational studies suggesting that higher meat consumption may be associated with lower dementia risk in ApoE4 carriers, challenging long-standing dietary narratives.The takeaway: your genes are one piece of the puzzle. Your daily choices, environment, and metabolic health may play a powerful role in shaping long-term brain outcomes.

How do we actually define “healthy food”? And how is it possible that processed, sugary cereals like Lucky Charms score higher than natural foods like eggs and meat in some food scoring systems?Dr. Bret Scher sits down with Dr. Ty Beal to explore a newly developed nutritional value scoring system designed to better reflect nutrient density, bioavailability, and chronic disease risk.Unlike many existing systems that can produce confusing or counterintuitive rankings, this approach aims to take a more comprehensive and transparent look at what makes food truly nourishing.In this interview, you'll learn:Why many popular food scoring systems fall shortWhat “nutrient density” really means and why it's more complex than it soundsHow bioavailability, protein quality, and nutrient diversity factor into food qualityThe role of ultra-processing, fiber, omega-3s, and nutrient ratios in shaping health outcomesWhy animal-source foods like meat, fish, eggs, and dairy can play an important role in a healthy dietHow this system can be adapted to different dietary patterns, including plant-based, omnivorous, and ketogenic approachesDr. Beal also shares the challenges of developing a system like this, from navigating scientific trade-offs to facing intense peer review, and why transparency and flexibility are essential when translating nutrition science into real-world tools.Importantly, this scoring system offers a framework to help individuals, clinicians, and policymakers better understand food quality within the context of overall dietary patterns and metabolic health. Rather than relying on overly simplistic labels like “good” or “bad,” tools like this can help guide more informed, personalized decisions.

Nurturing your relationship with yourself and your body can play a meaningful role in how you move forward from a mental health setback.Nicole Laurent shares a grounded, compassionate perspective on navigating setbacks. She explores how these moments can sometimes disrupt trust in ourselves, creating an internal tension that makes progress feel harder than it needs to be.She explores:Why setbacks can shake trust in your body, and how to rebuild itHow to approach challenges with curiosity instead of self-judgmentCommon triggers that can lead to going off trackHow mindset and framing influence long-term successHow your relationship with food and your body can evolve over timeThe key takeaway: setbacks are part of the learning process. Reconnecting with the idea that your body is working toward balance can help you move forward with more clarity, confidence, and resilience.

Is high LDL cholesterol always a red flag?For a growing group of people known as Lean Mass Hyper-Responders (LMHRs), the answer might not be so black and white.In this video, Dr. Bret Scher unpacks the science and questions behind LMHRs—metabolically healthy, lean individuals who see a dramatic rise in LDL cholesterol after starting a ketogenic diet. Unlike people with familial hypercholesterolemia (FH), their elevated LDL occurs in a unique metabolic context: low insulin, high HDL, low triglycerides, excellent metabolic health, and comes on only after adopting a ketogenic diet.

Are we destined for cognitive decline as we age, or do we have more control than we think?In this conversation, Dr. Bret Scher sits down with neuroscientist and researcher Dr. Tommy Wood to explore a powerful shift in how we think about brain health, aging, and dementia prevention.Dr. Wood challenges the common belief that cognitive decline is inevitable, highlighting how lifestyle, environment, and daily habits can meaningfully shape our brain's trajectory over time. He introduces his “3S Framework”—Stimulus, Supply, and Support—to explain how brain function is built, maintained, and optimized across the lifespan.In this interview, you'll learn:Why cognitive decline isn't inevitableHow mindset and engagement can influence brain agingThe role of metabolic health and energy supply in brain functionHow nutrition, sleep, exercise, and social connection interact to support the brainWhere ketogenic therapy and ketones may fit into brain health and cognitive declineHow to navigate modern challenges like technology, AI, and information overload from a brain health perspectiveDr. Wood also shares insights from his upcoming book, The Stimulated Mind, offering a practical framework to help individuals “future-proof” their brain and stay sharp in an ever-changing world.The key takeaway: brain health isn't about a single intervention. It's about consistently engaging, fueling, and supporting the brain in ways that promote resilience over time.

In this second video of our Bounce Back Series, Dr. Georgia Ede shares practical, compassionate guidance for returning to ketosis using simple, effective strategies rooted in diet and lifestyle.Rather than approaching setbacks with frustration or perfectionism, Dr. Ede emphasizes a mindset of curiosity and learning. Falling out of ketosis will happen and it's not a failure. With the right tools, you can use that information to refine what works best for your body.In this video, you'll learn:Why “ketosis interruptions” are normal and part of the processHow mindset plays a critical role in long-term successSimple strategies to return to ketosis quickly, including fasting and exerciseHow food choices can support appetite regulation and metabolic stabilityThe role of supplements like exogenous ketones and their limitationsWhy personalization is key to sustainable metabolic healthDr. Ede also explains the underlying physiology of ketosis: how insulin, glucose, and stored glycogen influence your body's ability to shift back into fat-burning mode.The key takeaway: consistency matters, but perfection isn't required. With the right approach, you can recover quickly, learn from the experience, and continue moving forward.

If you only read the headlines, it sounds simple: plants are protective, red meat is harmful. But when you examine the actual studies behind those claims, the conclusions aren't nearly so clear.In this video, Dr. Bret Scher takes a closer look at two recently published papers, one linking red meat consumption to diabetes risk and another suggesting vegetarian diets reduce cancer risk. Both studies rely on observational nutrition data, which can reveal associations but cannot prove cause and effect.In this video, you'll learn:Why many nutrition headlines oversimplify complex researchThe difference between observational studies and causal evidenceHow healthy user bias and lifestyle confounding can distort resultsWhy hazard ratios in nutrition studies are often too small to draw meaningful conclusionsHow media coverage and expert commentary can reinforce existing dietary narrativesDr. Scher explains why these studies may say more about overall lifestyle patterns like calorie intake, diet quality, alcohol use, and smoking, than about individual foods like red meat or plant-based diets.The bigger takeaway: nutrition science is nuanced, and the best diet for metabolic health may vary from person to person. Instead of focusing on simplistic narratives like “meat bad, plants good,” we should focus on improving overall dietary quality and metabolic health.

In this special episode of Metabolic Mind, Dr. Julie Milder, Director of Neuroscience at Baszucki Group, speaks with Dr. Fabiano Gomes, psychiatrist and researcher at McMaster University, and the inaugural recipient of the Baszucki Group Metabolic Psychiatry Scholar Award.Dr. Gomes recently published a pilot feasibility trial of a ketogenic diet for depression in the Journal of Affective Disorders. In this conversation, he shares how the study came together, what the results revealed, and why metabolic approaches may offer new hope for people struggling with treatment-resistant depression.In this episode, they discuss:The pilot ketogenic diet trial for depression and its key findingsHow the study successfully transitioned to a fully remote clinical trial during COVIDWhat the results suggest about feasibility, adherence, and clinical improvementsThe role of nutritional ketosis in mood disorders and metabolic psychiatryDr. Gomes' vision for launching a Metabolic Psychiatry Clinic in CanadaPlans to integrate biomarkers, brain imaging, and real-world clinical careThe importance of training clinicians and dietitians to expand access to metabolic therapiesDr. Gomes's work represents an exciting step forward in the growing field of metabolic psychiatry, which explores how metabolism and brain energy may influence conditions like depression, bipolar disorder, and other mental health disorders.The conversation also highlights the importance of building clinical infrastructure and training programs to make metabolic therapies more accessible to patients today.

Setbacks are a natural part of any journey, and mental health recovery is no exception. In this video, Dr. Matt Bernstein shares a powerful perspective on why downturns aren't failures, but opportunities to learn, adapt, and build resilience.Rather than viewing setbacks as something to fear or avoid, Dr. Bernstein explains how adopting a growth mindset can transform the way we respond to challenges. With the right preparation and support, moments of struggle can become key turning points in long-term recovery.In this video, you'll learn:Why setbacks are normal in any recovery journeyHow to reframe “failures” as opportunities for growthThe importance of identifying early warning signsHow to build a personal plan for navigating downturnsWhy support systems and connection are critical during difficult timesHow tools like mindfulness and structured planning can help you regain momentumDr. Bernstein also discusses practical strategies like creating a Wellness Recovery Action Plan, leveraging your support network, and even planning ahead for more serious crises with tools like a healthcare proxy.If you're navigating mental health challenges or supporting someone who is, this conversation offers practical tools and a more compassionate framework for the journey.

Can a ketogenic diet improve mental health?This week marks a significant moment for metabolic psychiatry and ketogenic therapy for serious mental illness.A New York Times piece highlighted early research from Stanford University, The Ohio State University, and the University of Edinburgh—alongside stories from individuals who have shared their lived experience here on Metabolic Mind.This kind of visibility matters. It reflects years of work by researchers and clinicians like Drs. Chris Palmer, Shebani Sethi, and Iain Campbell, research funded by Baszucki Group, advocates like Jan Baszucki, as well as the many people who have been willing to share their personal stories.Lived experience alone isn't enough. Early data alone isn't enough. But together, they point to something that must be tested, confirmed — or challenged — through high-quality science. That's why we are excited about several RCTs currently completed or underway around the world.We need to continue efforts to advance education, public awareness and research on a scale that will require public funding. That's how medicine moves forward. And that's the exciting work ahead.

Can the ketogenic diet help improve symptoms for individuals living with treatment-resistant depression?In this conversation, Dr. Bret Scher sits down with Dr. Megan Kirk Chang, a senior researcher in metabolic psychiatry at the University of Oxford and a co-author of the recently published DIME trial.This study represents the first randomized clinical trial to evaluate a ketogenic diet in adults with treatment-resistant depression.Participants were assigned to either a ketogenic diet or a plant-rich comparison diet for six weeks to assess whether dietary intervention could influence depressive symptoms. Both groups experienced meaningful improvements in depression scores, with the ketogenic diet slightly outperforming the control group at 6 weeks.While the difference between groups did not reach the threshold for statistical significance, the findings suggest a positive signal that warrants further investigation.In this interview, Dr. Kirk Chang reflects on:The strengths of the study and where she sees opportunity for improvement.What the modest difference between diets might meanWhy early pilot trials are designed to detect signals rather than definitive answersWhat the study revealed about adherence, cravings, and behavioral factorsHow these results will inform larger and longer clinical trials now being plannedAs Dr. Kirk Chang explains, this six-week pilot trial was designed as proof-of-concept research to determine whether there is enough signal to justify larger studies in metabolic psychiatry.At Metabolic Mind, we view studies like this as an important step in a growing scientific effort to understand how metabolism and nutrition may influence serious mental illness. Each new study contributes to the evolving evidence base that will help researchers determine who may benefit, why, and under what conditions.

A new meta-analysis just dropped, and once again, saturated fat takes center stage. But does the data actually support the decades-long warnings we've heard about saturated fat and heart disease? Not exactly.In this video, Dr. Bret Scher dives deep into a recent study published in the Annals of Internal Medicine that reviewed randomized controlled trials on saturated fat intake and health outcomes.Despite the headlines and abstract language hinting at risk, a closer look at the data reveals no statistically significant increase in heart attacks, strokes, or early death, even with modest increases in LDL.So why the disconnect between what the data shows and what the authors claim? Dr. Scher breaks it down and explores the nuances often missing from the conversation about saturated fat, including context like food quality, carbohydrate intake, metabolic health, and lifestyle factors that make a big difference.

You may have seen headlines or social media posts claiming that ketones increase the risk of heart attacks and that this proves ketogenic diets are dangerous for heart health. But when you actually examine the study behind those claims, the data tell a very different story.In this video, Dr. Bret Scher takes a closer look at a recent paper published in the Journal of the American Heart Association that analyzed circulating ketone levels in participants from the UK Biobank. The study has been widely shared online as evidence against ketogenic diets. The issue? The participants weren't following a ketogenic diet at all.Instead, researchers measured very small baseline ketone levels in a general population that was consuming around 250 grams of carbohydrates per day, that's far from the levels associated with nutritional ketosis.In this video, you'll learn:Why this study was not a ketogenic diet studyThe difference between association and causation in epidemiologyWhy the measured ketone levels were far below nutritional ketosisHow metabolic stress, illness, or diabetes can raise ketone levels independently of dietWhy these findings don't tell us anything about ketogenic dietsUnderstanding the context behind nutrition research is critical. Misinterpreting observational data can easily lead to misleading headlines and unnecessary confusion about diet and health.

Can you reverse fatty liver disease with a ketogenic diet?Fatty liver disease is now one of the fastest-growing liver conditions in the world, affecting roughly 30% of adults and an increasing number of children. And in many cases, it's driven by metabolic dysfunction and insulin resistance.In this conversation, Dr. Bret Scher speaks with Dr. Amy Goss (University of Alabama at Birmingham) and Dr. Karen Jerome-Zapadka (Trajectory Health Partners) about the growing epidemic of metabolic dysfunction–associated steatotic liver disease (MASLD) and why carbohydrate restriction and ketogenic nutrition may be powerful tools for addressing it.In this interview, you'll learn:What MASLD (formerly NAFLD) is and why it's becoming so commonHow insulin resistance and excess carbohydrates contribute to fatty liverNew research showing how carbohydrate restriction can reduce liver fatWhy ketogenic and low-carb diets may improve liver metabolism beyond weight lossThe clinical experience of reversing fatty liver through metabolic therapyWhy lifestyle approaches often receive less attention than medicationsDr. Amy Goss and her team at the University of Alabama at Birmingham are currently conducting a large NIH-funded clinical trial investigating how carbohydrate restriction affects liver fat and insulin sensitivity in adolescents with fatty liver disease.At the same time, Dr. Karen Jerome-Zapadka is applying these metabolic principles in clinical practice at Trajectory Health Partners, helping patients reverse steatotic liver disease through carbohydrate reduction and comprehensive metabolic care. Together, their research and real-world clinical experience are helping advance a deeper understanding of how targeting metabolic dysfunction may transform the way fatty liver disease is treated.Curious about the safety of ketogenic therapy? Visit our Is Keto Safe topic page to see all of our top content on the topic: https://www.metabolicmind.org/resources/topics/is-keto-safe/

A new meta-analysis of 174 randomized controlled trials on “carbohydrate-restricted diets” found consistent benefits for body composition, blood pressure, inflammation, and more. But instead of highlighting the metabolic benefits, most of the headlines focused almost entirely on a small bump in LDL.In this video, Dr. Bret Scher breaks down why that reaction misses the point and how biases in nutrition reporting are holding back real progress in improving metabolic health.

Are there real contraindications to a ketogenic diet? Yes, but they're far rarer than many people think. So who shouldn't do keto?In this video, Dr. Bret Scher breaks down the difference between absolute and relative contraindications to ketogenic therapy. While rare inborn metabolic disorders and certain acute illnesses are true absolute contraindications, most commonly cited concerns, including type 1 or type 2 diabetes, heart disease, serious mental illness, high cholesterol, and even pregnancy are listed as relative contraindications, which really means, “use caution and work with an experienced clinician.”Watch to learn who should avoid ketogenic therapy, who may benefit, and why clinical guidance makes all the difference.

Ketogenic therapy for schizophrenia, bipolar disorder, and depression is gaining attention, but how can it be safely implemented into clinical practice?A newly published expert consensus provides practical recommendations to help clinicians thoughtfully apply ketogenic metabolic therapy (KMT) for serious mental illnesses.In this in-depth conversation, Dr. Matt Bernstein and Dr. Georgia Ede, both members of the expert committee, discuss how this Delphi consensus was developed, what it includes, and how it can be responsibly integrated into psychiatric practice.In this interview, they discuss:What a Delphi process is and why it was usedThe results of the Delphi process (33 consensus statements and 10 clinical recommendations)Who may be appropriate candidates for KMTAbsolute and relative contraindicationsRecommended laboratory screening and monitoringHow long a trial should last before assessing efficacyHow clinicians can personalize implementation safelyImportantly, the authors emphasize that ketogenic metabolic therapy is not a replacement for standard psychiatric treatment. Rather, it may be considered alongside first-line therapies, particularly for individuals who have not responded adequately, cannot tolerate medications, or are seeking additional options.Reflecting on the value of this work, Dr. Bernstein shares:“I would have loved to have read this six years ago when I was starting to think about implementing these types of practices. It would have given me confidence to charge forward… I probably would have been further along now than I am.”With randomized controlled trials ongoing and more research expected in the coming years, this consensus provides a thoughtful, experience-informed framework for clinicians who are seeing growing interest in metabolic approaches.If you are a clinician, we encourage you to read the full publication.If you are a patient or family member, consider sharing this interview and the paper with your care team to support an informed discussion about whether metabolic strategies may be appropriate in your individual case.As always, clinical decisions should be made in partnership with qualified healthcare professionals.

Is a low-carb diet bad for your health? A recent New York Times article suggests so, but it leaves out critical context about ketogenic metabolic therapy and the role of metabolic health in chronic disease.In this video, Dr. Bret Scher explains why balanced reporting on low-carbohydrate and ketogenic diets truly matters, especially for people with insulin resistance, type 2 diabetes, PCOS, fatty liver disease, and many psychiatric conditions. Ketosis isn't simply “eating fewer carbs.” It's a distinct metabolic state that shifts the body's primary fuel source and has documented therapeutic benefits in multiple conditions.In this video, you'll learn:What nutritional ketosis actually is, and how it differs from general healthy eatingWhy, for some individuals, carb quantity matters just as much as carb qualityThe clinical evidence supporting ketogenic therapy for diabetes, PCOS, fatty liver, epilepsy, and mental healthWhile it's true that not everyone needs to follow a low-carb or ketogenic diet, dismissing it without a clinical perspective does a disservice to the many who could benefit.

How can doctors, psychiatrists, and other health practitioners implement keto for serious mental illnesses like schizophrenia, bipolar disorder, and depression?In this short interview, Dr. Bret Scher sits down with Dr. Georgia Ede to discuss a newly published Delphi consensus paper in Frontiers in Nutrition, authored by eight experienced clinicians and researchers to establish best practices for the use of ketogenic metabolic therapy (KMT) in serious mental illnesses.Using a structured expert consensus process, the group created 33 statements clarifying things like:What ketogenic metabolic therapy isWho may be appropriate candidates?Safety considerations and medical screeningMonitoring standards and clinical implementationHow KMT can be integrated alongside standard psychiatric careThese statements were then brought to a larger group of experienced clinicians to assess broader consensus, which resulted in all 33 statements reaching the consensus threshold.This paper is not a set of formal treatment guidelines. Instead, they represent an important first step in delivering practical, experience-informed guidance for clinicians who are seeing growing patient interest in metabolic approaches to serious mental illnessAs research continues to evolve, this consensus provides a thoughtful framework for psychiatrists, primary care clinicians, therapists, dietitians, and multidisciplinary teams who wish to incorporate ketogenic metabolic therapy into individualized treatment plans.If you are a clinician interested in learning more about metabolic approaches in psychiatry, we encourage you to explore the full publication.If you are a patient or family member, consider sharing this paper with your care team to start an informed discussion about whether metabolic strategies may be appropriate in your individual case.With the clinical evidence still accumulating and randomized controlled trials ongoing, we expect this clinical guidance to continue to evolve as more data and real word experience becomes available.

Polycystic Ovary Syndrome (PCOS) is the leading cause of infertility in women, but what if the real issue isn't the ovaries?In this eye-opening conversation, Dr. Bret Scher speaks with Dr. Steven Palter, reproductive endocrinologist and founder of Gold Coast IVF, about the powerful connection between PCOS, metabolic health, mental health, and fertility.For decades, PCOS has been treated symptom-by-symptom: birth control for irregular cycles, fertility drugs for ovulation, IVF for infertility. But Dr. Palter explains why this approach often misses the root cause: insulin resistance and metabolic dysfunction.When you address the metabolic driver, everything can change.Ketogenic and low-carbohydrate dietary approaches are showing promise in improving insulin sensitivity, restoring ovulation, improving mood, and even supporting fertility, often before significant weight loss occurs. In many cases, women who were preparing for IVF are conceiving naturally after correcting their metabolic health.In this video, you'll learn:Why PCOS is best understood as a metabolic disorderHow insulin resistance drives infertility, mood changes, and long-term health risksWhy traditional “eat less, move more” advice often failsHow ketogenic therapy may restore ovulation and improve fertilityThe connection between PCOS, depression, and binge eatingWhy GLP-1 medications aren't the same as metabolic repairIf you or someone you know is struggling with PCOS, infertility, or unexplained hormonal symptoms, this episode offers a hopeful and science-based perspective on what's possible when metabolic health becomes the priority.As always, consult your healthcare provider before making significant dietary changes.

February is Heart Health Month, making it the perfect time to challenge common misconceptions about diet and cardiovascular health.One claim that always resurfaces? That ketogenic diets are bad for your heart. But when you take a closer look at the science, that assumption simply doesn't hold up.In this video, Dr. Bret Scher breaks down the real evidence behind ketogenic diets and cardiovascular risk, addressing:✅ How many “keto” studies don't actually study true ketogenic diets✅ The truth about LDL cholesterol on keto (it doesn't go up for everyone!)✅ Why triglycerides, HDL, insulin, and inflammation may matter more than LDL✅ How keto compares to DASH for blood pressure and metabolic health✅ Why saturated fat from real food behaves differently in the body✅ The critical difference between ultra-processed high-fat/high-carb diets and low-carb, whole-food ketogenic diets

Is there evidence that the ketogenic diet can cure schizophrenia?Recent comments from HHS Secretary Robert F. Kennedy Jr. sparked headlines…and controversy. While “cure” isn't the right word, the conversation has brought much-needed attention to an emerging field: metabolic psychiatry.In this video, Dr. Bret Scher breaks down what the science actually shows about ketogenic metabolic therapy as a potential adjunctive treatment for serious mental illness, including schizophrenia, bipolar disorder, and major depressive disorder.You'll learn about:What nutritional ketosis is and why brain energy matters for serious mental illnessHow psychiatric conditions like schizophrenia, bipolar disorder, and major depressive disorder involve underlying metabolic dysfunctionEarly evidence on ketogenic therapy for serious mental illness from Stanford, Edinburgh, and The Ohio State UniversityHow consistent lived experiences aligned with emerging clinical data warrant serious scientific explorationWhat new research is on the wayKetogenic therapy is emerging as a serious metabolic strategy that may expand how we think about treating complex psychiatric conditions. We are now faced with the opportunity to study it rigorously, apply it thoughtfully, and ensure patients have access to every tool that could help.

In this powerful interview, Dr. Bret Scher speaks with Dr. Robin Engelhardt, a German researcher and PhD in psychology, who is launching a pilot study investigating ketogenic metabolic therapy as a treatment for PTSD and complex PTSD.Using his own personal experience of healing from PTSD through nutritional ketosis, Dr. Engelhardt is now launching a pilot study to explore whether this approach can help others. His pilot study will test feasibility, safety, and symptom response, paving the way for future randomized controlled trials.

Saturated fat is back in the headlines, and so is the confusion.The new Dietary Guidelines for Americans just dropped, and while there's clear progress (more support for animal-based protein, low-carb options, and reduced sugar), they've kept the 10% cap on saturated fat. But does the science still support that limit, and does it make sense with the rest of the recommendations?In this episode, Dr. Bret Scher breaks down the real story on saturated fat: where the guidelines get it right, where they fall short, and why context is everything when it comes to fat, food, and metabolic health.He covers:✅ The 5 main types of evidence on saturated fat✅ Why source and dietary context matter more than grams✅ What randomized trials, ketogenic studies & LDL data really show✅ The problem with lumping steak and pizza into one category✅ Why blanket limits may harm people trying to improve their metabolic healthThe saturated fat debate isn't just about grams, it's about individual metabolic health. When we zoom out and look at the full picture, it becomes clear that not all saturated fat is created equal. Understanding where it comes from and how it fits into an overall dietary pattern is key to moving the conversation forward.

In this deeply personal and powerful conversation, Metabolic Mind founder Jan Ellison Baszucki joins mental health advocate Laura Delano to share a mother's journey through her son's bipolar disorder diagnosis, years of psychiatric crisis, and ultimately, hope.After five years, 29 medications, multiple hospitalizations, and a system that offered few lasting solutions, Jan's son Matt found real and sustained stability through metabolic therapies, including a therapeutic ketogenic diet.In this conversation, you'll hear:• What it's like to navigate the mental health system as a parent• How conventional care fell short, and what was missing• Why Jan calls metabolic psychiatry “energetic medicine for the mind”• How diet, sleep, light, and lifestyle can transform mental health• A powerful message for other families searching for answersThis experience didn't just transform Jan's family; it sparked a mission. Jan and her family founded Metabolic Mind to raise awareness about the therapeutic potential of metabolic interventions for serious mental illness. Today, Metabolic Mind is helping to bridge the gap between psychiatry and metabolic health by supporting research, educating clinicians and families, and empowering those still searching for answers.

Can a ketogenic diet help with depression when other options have failed? Emerging suggests the answer may be yes.In this video, Dr. Bret Scher shares the latest clinical data on ketogenic therapy for depression, including two new studies showing meaningful improvements, even remission, in people with moderate to severe symptoms. For individuals struggling with treatment-resistant depression, these findings offer real hope and open the door to a new therapeutic pathway: metabolic interventions that target brain energy.In this video, you'll learn:How ketosis may support brain function and mental healthWhat two new pilot studies reveal about keto for depression and anhedoniaHow researchers are beginning to rethink the metabolic roots of mood disorders

The second-ever pilot trial (published in the Journal of Affective Disorders) is making waves: a virtual medically supervised ketogenic diet showed impressive improvements in people with moderate to severe depression, including nearly 7 out of 8 study completers achieving clinical remission.In this interview, Dr. Bret Scher sits down with lead researcher Dr. Elisa Brietzke, Professor of Psychiatry at Queen's University, to explore the inspiration, execution, and implications of this study.What began as a bold idea, that metabolic dysfunction plays a role in depression, evolved into a fully remote clinical intervention. Despite skepticism and challenges, the results were clear: ketogenic therapy can be safely and effectively implemented in a remote outpatient setting. Participants who completed the study experienced improvements in depression, anxiety, and anhedonia (the loss of pleasure).In this conversation, Dr. Brietzke shares:Why she turned to metabolic therapy for mental healthHow the team pulled off a fully remote ketogenic trial during the pandemicThe science behind how inflammation, insulin resistance, and brain energy affect moodWhy traditional antidepressants often fail to address anhedoniaWhat's next for research, and how this could shape depression treatment guidelines

The 2025-2030 Dietary Guidelines for Americans have arrived, and they're sparking serious debate. Are we finally seeing a meaningful shift toward metabolic health? What do the guidelines get right, and where is there still room for improvement?To unpack it all, Dr. Bret Scher is joined by two long-time voices in nutrition science: Dr. David Ludwig and Gary Taubes. Together, they dig into what the new guidelines get right, what they overlook, and what this all means for public health, clinical practice, and the food industry.They explore:The shifting stance on animal protein, and the controversy it's stirredA long-overdue move away from refined carbohydratesWhy the term “ultra-processed food” was intentionally left outThe important nod to low-carb diets for chronic diseaseHow school lunches and government food programs may (or may not) changeThe tension between dietary health and environmental goalsWhy robust clinical trials, not just policy documents, are urgently neededThis lively discussion blends agreement, disagreement, and deep insights into what these guidelines mean, not just on paper, but in real life. Whether you're a clinician, policymaker, parent, or just trying to eat healthier, this episode will help you rethink the “official” nutrition narrative.

Can a ketogenic diet affect cardiovascular risk? Do nuts belong in a low-carb diet? What about ice cream, supplements, and electrolytes?In this episode of Metabolic Mailbag, Dr. Bret Scher tackles some of the most common and misunderstood questions about ketogenic therapy for metabolic and mental health. From concerns about LDL cholesterol to fears of liver and kidney damage, this conversation cuts through the noise with nuance, evidence, and practical guidance.This episode covers:LDL cholesterol spikes on a ketogenic diet: what's normal, what's not, and how to think beyond one lab numberStatins vs. individualized risk assessment (imaging, metabolic markers, trends over time)How nuts fit into a ketogenic diet and when they become a problemKetogenic diets and liver/kidney health: what human data actually shows“Good keto” vs. “bad keto” and the role of whole foodsSupplements, electrolytes, and when they're truly neededSnacking, sweeteners, keto desserts, and staying in ketosisWhether you're just starting a ketogenic diet or fine-tuning it for long-term metabolic or mental health, this episode offers clarity where confusion is common. By unpacking real-world questions with a clinical lens, Dr. Scher empowers you to think critically, personalize your approach, and make decisions rooted in human evidence—not fear or headlines.Do you have more questions? Check out our other Mailbag Q&A episodes with Dr. Bret Scher and Dr. Georgia Ede:Episode 1: https://youtu.be/PDgM-SD3Fx4Episode 2: https://youtu.be/3m6Fm0nXaMQEpisode 3: https://youtu.be/UgaaYl6RPbsEpisode 4: https://youtu.be/roMq4YU58rcEpisode 5: https://youtu.be/_eSVU5_P7YsEpisode 6: https://youtu.be/TcfGZ3m-lzE

Is carb-loading really the key to endurance and performance? A groundbreaking 100-page publication led by Dr. Andrew Koutnik says it's time to question the dogma.For decades, athletes have been told that more carbs mean better performance. Strategies like carb-loading before and using sugary gels during exercise have become staples of endurance performance.But recent research has unveiled a shocking truth. Many athletes, even those who look healthy on the outside, are showing glucose levels consistent with prediabetes on the inside.In this interview, Dr. Bret Scher and Dr. Andrew Koutnik unpack the new landmark publication that challenges outdated sports nutrition guidelines and reveals another approach to fueling human performance.

In this special Metabolic Mailbag episode, cardiologist Dr. Bret Scher steps into the hot seat to answer your most pressing questions about ketogenic therapy, heart health, and metabolic markers. Drawing directly from listener questions, this conversation tackles the confusion and concern many people face when lab results change after starting a ketogenic diet.

The science of metabolic psychiatry is advancing, but the movement behind it is just getting started. In this episode, Dr. Bret Scher sits down with Natasha Smikles and Eddie Rodriguez from Metabolic Collective, a new nonprofit working to build an international advocacy network for ketogenic and metabolic therapies.Their goal: accelerate awareness, adoption, and support for metabolic interventions in mental health.They cover:The personal journeys that led Natasha and Eddie to metabolic therapyWhy lived experience is such a powerful driver of changeWhy Metabolic Collective was created, and who it's forHow Metabolic Collective is organizing community-led advocacy and educationWhat tools, resources, and events are available to help you get involvedHow to support others, start a local group, or bring metabolic psychiatry into your communityMetabolic psychiatry is growing, and movements like this are helping close the gap between research and real-world impact. From mental health challenges to neurological disorders, the Metabolic Collective hopes to spread the word about metabolic therapies and empower patients with alternative options to standard of care.

Is caffeine sabotaging your mental health progress? Should you try a carnivore diet if keto isn't working? What if your meds lower ketones?In this new Metabolic Mailbag episode, Dr. Georgia Ede joins Dr. Bret Scher to answer your most pressing questions about metabolic therapies, mental health, and more.Together, they dive into nuanced, evidence-informed conversations about:The real impact of caffeine on mood, sleep, and ketosisWhether the carnivore diet is “too high” in proteinWhy some people see mental health improvements on carnivore when a ketogenic diet hasn't workedWhat to do when medications interfere with ketone levels, and why deprescription must be done safely and strategicallyAnd moreMetabolic psychiatry is a promising frontier, and we're here to empower individuals navigating serious mental illness with tools and knowledge rooted in science, compassion, and real-world experience.

Do SSRIs help your brain?SSRI medications are among the most widely prescribed antidepressants, but what if we've misunderstood how they work? In this interview, Dr. Bret Scher sits down with biochemist and nutrition scientist Dr. Chris Masterjohn to explore a deeper, more systemic view of mental health and how we treat it.Dr. Masterjohn reveals why serotonin isn't just a “mood booster,” how SSRIs may be disrupting mitochondrial function, and why focusing on lifestyle strategies that support brain energy metabolism could unlock new paths for treating depression.

Is carb-cycling okay on a ketogenic diet? What about high histamine foods?In this episode of Metabolic Mailbag, Dr. Bret Scher and Dr. Georgia Ede answers questions on everything from the best sources of dietary fat to how to handle anxiety, perimenopause, and alcohol while maintaining ketosis.They unpack how to build a nutrient-dense, brain-supportive ketogenic diet using whole foods, why “keto-friendly” processed products can sometimes derail progress, and when supplements might be beneficial. You'll also learn why histamine sensitivity, caffeine, or cycling in and out of ketosis can affect mood, and how to troubleshoot each.This conversation covers:Why a whole food ketogenic diet can be ideal for mental healthHow to identify the best fat sources and avoid “factory fats”Ketogenic dieting for women's healthWhy anxiety can worsen mid-journey, and how to adaptThe truth about alcohol, carb cycling, and ketosisIf you're exploring ketogenic therapy for mental or metabolic health, this episode offers practical, science-based guidance to help you refine and personalize your approach.

New research links chronic stress, brain energy, and psychiatric conditions, including PTSD, depression, and bipolar disorder.Stress doesn't just impact your mood; it affects how your brain allocates energy. In this interview, Dr. Bret Scher sits down with Dr. Parker Kelly, a postdoctoral fellow at UCSF and the San Francisco VA, to unpack the Allostatic Triage Model of Psychopathology, a new framework proposing that psychiatric symptoms may emerge when the brain is forced to triage limited metabolic resources under chronic stress. Co-authored with mitochondrial researcher Dr. Martin Picard, this model could shift how we understand and treat mental illness.In this conversation, you'll learn:How stress drives brain energy dysfunctionWhy mitochondria and metabolism may be central to mental illnessWhich brain networks are impacted by energy deficitsThe role of predictability and routine in stress resilienceHow metabolic therapies like nutrition, sleep, and even psychedelics, may support brain energy regulationThis conversation bridges neuroscience, metabolism, and mental health, offering a unique and unifying lens on complex psychiatric conditions.

Novo Nordisk, the pharmaceutical company behind popular GLP-1 medications like Wegovy and Ozempic, recently announced that its phase 3, two-year trial examining GLP-1 medications for Alzheimer's failed to produce a significant reduction in disease progression.While these results are discouraging, they may have revealed something vital about Alzheimer's treatment.In this video, Dr. Bret Scher breaks down the recent failure of Novo Nordisk's evoke and evoke+ trials and what it teaches us about the limitations of a drug-only approach to Alzheimer's treatment.Key topics covered:Why GLP-1s may not be enough for Alzheimer'sThe link between glucose metabolism and brain energy failureHow ketones offer an alternative fuel for the brainEarly research on ketogenic therapy for cognitive impairmentWhy nutritional interventions deserve more scientific attentionWith Alzheimer's affecting millions and costing billions, it's time to shine a light on metabolic strategies that directly support brain energy, reduce inflammation, and improve cognitive function.

What if your diagnosis of type 2 diabetes, high blood pressure, or fatty liver wasn't a permanent sentence, but a condition that could improve or even reverse through targeted intervention?In this episode of the Metabolic Mind podcast, Dr. Bret Scher sits down with Dr. Adam Wolfberg, Chief Medical Officer at Virta Health, to explore groundbreaking data that challenges the conventional approach to managing chronic metabolic disease. They dive into Virta's latest annual report, which highlights powerful clinical and economic outcomes that could reshape the future of medicine.In this interview, you'll learn:Why "reversal" is replacing "management" in the metabolic care conversationHow Virta's data shows a 56% reduced risk of heart attack, stroke, or deathThe role of carbohydrate-restricted and ketogenic nutrition in improving metabolic healthHow patients across socioeconomic backgrounds, including those in food deserts, are seeing resultsWhere medications like GLP-1 fit into a lifestyle-first modelWhat this model means for healthcare costs, medication reduction, and long-term patient outcomesVirta's annual report highlights how a shift toward value-based care and personalized, nutrition-driven approaches can drastically improve patient outcomes.Check it out here: https://www.virtahealth.com/reversal-report#MetabolicMind #KetogenicTherapy #MetabolicHealth #FoodAsMedicineExpert Featured:Dr. Adam WolfbergChief Medical Officer at Virta Healthwww.Vitrahealth.comLinkedIn.com/in/adamwolfbergResources Mentioned:Virta's 2025 Annual Report on Metabolic Disease Reversalhttps://www.virtahealth.com/reversal-reportHealthcare utilization and cost impact of telehealth-delivered nutrition therapy for type 2 diabetes and obesity: a retrospective claims-based studyhttps://doi.org/10.1101/2025.11.09.25339829Real-World Cardiovascular Outcomes with a Carbohydrate-Reduced Telemedicine Interventionhttps://doi.org/10.1101/2025.10.27.25338916Reduced Onset of MASLD, MASH, and Advanced Liver Disease in patients who received Individualized Nutrition-Focused Remote Care for Adults with Type 2 Diabetes and Obesityhttps://doi.org/10.1101/2025.10.24.25338753Effectiveness of telehealth nutritional therapy in preventing chronic kidney disease among adults with type 2 diabetes and obesity: a real-world, retrospective, propensity score–matched cohort studyhttps://doi.org/10.1101/2025.10.17.25338238Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and

Ever wonder why your ketone levels dip after a few months on a ketogenic diet? Or how exogenous ketones compare to ketones produced naturally?In this Metabolic Mailbag episode, Dr. Bret Scher and Dr. Georgia Ede unpack the latest round of keto questions asked by the community.

What does it really look like to heal a serious mental illness with ketogenic therapy?At Metabolic Mind, we often highlight powerful stories of individuals putting serious psychiatric conditions into remission with ketogenic and metabolic therapies. But healing isn't always linear, and it's rarely easy.In this honest and deeply human episode, Dr. Bret Scher and Dr. Georgia Ede sit down with Matt Baszucki and Lauren Kennedy West to explore the real-world challenges of using ketogenic therapies for mental health.Together, they discuss:The emotional and practical realities of tapering psychiatric medicationsNavigating variable ketone levels and the effect on mood, cognition, and stabilityThe stigma around diet and mental illness, and the power of self-trustWhat it takes to sustain long-term lifestyle change (and the benefits of support)How setbacks can become opportunities for growth, resilience, and self-discoveryWhether you're just starting a metabolic therapy or supporting someone who is, this conversation offers validation, insight, and encouragement to keep going — even when the path is hard.

Is the diet being promoted to “save the planet” actually based on environmental data?In this eye-opening interview, Dr. Frank Mitloehner, air quality specialist and director of the CLEAR Center at UC Davis, unpacks the claims behind the EAT-Lancet 2.0 report, particularly the idea that cutting animal-sourced foods will drastically reduce environmental harm. Despite widespread media framing it as a climate solution, Dr. Mitloehner reveals that the Planetary Health Diet is not grounded in environmental science at all — a fact even confirmed in the report's own glossary.He also highlights a key finding from the UN's FAO: shifting to plant-based diets was ranked among the least effective ways to reduce livestock-related emissions, far behind solutions like improving animal health and increasing productivity.

People living with serious mental health conditions face a dramatically higher risk of premature death, not only from psychiatric symptoms, but from the cardiometabolic complications that often accompany their treatment.Despite decades of awareness, this critical issue remains under recognized and under treated. In this episode of the Metabolic Mind podcast, Dr. Bret Scher speaks with two leading experts who are changing that:Dr. Margaret Hahn, Clinician Scientist in the Schizophrenia Division at the Center for Addiction and Mental Health (CAMH) and Professor of Psychiatry at the University of Toronto.Dr. Sharmili Edwin Tharanajah, Physician and Research Associate at the University Hospital Frankfurt's Clinic for Psychiatry, Psychosomatics, and Psychotherapy.Together, they unpack groundbreaking research on the metabolic consequences of psychiatric care, including antipsychotic-induced glucose dysregulation, obesity, and insulin resistance and explore how clinicians can better prevent, detect, and manage these risks.

In this episode of the Metabolic Mind podcast, Dr. Bret Scher speaks with L.J. Amaral, a registered dietitian, certified in nutrition oncology, and PhD student researcher at Cedars-Sinai, about where ketogenic therapy may fit into cancer care. Together they emphasize a crucial point: in oncology, we're not just treating the tumor, we're treating the whole person. The quality of life, physical strength, and day-to-day function of patients matter in prognosis.L.J. covers:How shifting fuel toward ketones may influence metabolism, inflammation, fatigue, and even muscle preservation during treatment.Why many tumors crave glucose, and why that matters for dietary strategies.The potential of ketogenic therapy used alongside standard of care (surgery/chemo/radiation), with early signals around feasibility, daily living, and patient well-being.The real-world nuance of responders vs. non-responders, and why personalized coaching is key.How some patients pair fasting windows with treatment, and the practical safeguards to consider.What's next: details on an NIH-funded, multi-center phase 2 trial comparing a ketogenic approach to an American Cancer Society–style diet.Ketogenic therapy in oncology is early but advancing. If you're curious about science-backed nutrition strategies that support both treatment and daily life, this conversation is for you.

Thinking about reducing or stopping psychiatric medication? It may not be the right approach for everyone, but for someone considering it, there's much to keep in mind.For instance, many individuals who adopt ketogenic therapy and other metabolic strategies often find themselves in need of reducing medication. But how can they do it safely and with minimal risk?In part 2 of our 2-part series on med tapering, Dr. Bret Scher and ‪@GeorgiaEdeMD‬ dive deep into how to safely and effectively taper psychiatric medications, offering guidance, caution, and hope for those exploring this path.Tapering antidepressants, antipsychotics, or mood stabilizers can be one of the most complex challenges in mental health care and it can come with serious risks. Dr. Ede breaks down what most clinicians miss about withdrawal, and why “slow and steady” isn't just advice, it's a necessity. She also explains how strategies like ketogenic therapy and other lifestyle interventions can support brain stability during the process.In this episode, you'll learn:✅ Why individuals are looking to reduce or remove medication✅ The potential risks of not safely tapering✅ The “no sudden movements” rule and the concept of hyperbolic tapering✅ Tools and resources for safer dose reductions (compounding pharmacies, taper strips, and more)✅ How to increase your chances of feeling better with no or less medication✅ The role of metabolic health, nutrition, sleep, and stress management in effective tapering✅ What to do if your doctor is hesitant or resistant to adjusting your medication✅ Why you may want to consider avoiding supplementing during a taper

The EAT-Lancet Commission recently released their updated "Planetary Health Diet" and preemptively labeled a number of health experts who pushed back as “mis-influencers.”Dr. Georgia Ede was one of those health experts labeled and in this episode of the Metabolic Mind podcast, she joins Dr. Bret Scher to unpack the many flaws of the EAT-Lancet 2.0 report.In this episode, you'll learn about:The deep flaws in claiming a one-size-fits-all solution to diet and planetary health.EAT-Lancet's heavy reliance on weak epidemiological dataIts open acknowledgment of nutrient deficiencies in the EAT-Lancet diet and who is most at riskWhy animal-sourced foods are beneficial for our health—especially for brain healthHow ideology and influence may be driving public health messagingDr. Ede's response to being labeled a “mis-influencer”At Metabolic Mind, we believe optimal human nutrition begins with asking the right scientific questions—starting with what's healthiest for the brain and body, then considering sustainable solutions.Human and planetary health are too complex for one-size-fits-all solutions—and if such a diet existed, we wouldn't uncover it through untested epidemiological guesswork.Expert Featured:Dr. Georgia EdeWebsite: https://www.diagnosisdiet.com/Book: https://www.diagnosisdiet.com/change-your-diet-change-your-mindYouTube: ‪@GeorgiaEdeMD‬X: https://xResources MentionedEat LancetFree CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of Baszucki Group working to transform the study and treatment of mental disorders by exploring the connection between metabolism and brain health. We leverage the science of metabolic psychiatry and personal stories to offer education, community, and hope to people struggling with mental health challenges and those who care for them.Our channel is for informational purposes only. We are not providing individual or group medical or healthcare advice nor establishing a provider-patient relationship. Many of the interventions we discuss can have dramatic or potentially dangerous effects if done without proper supervision. Consult your healthcare provider before changing your lifestyle or medications.

Psychiatric medications have become a standard of care for many mental illnesses. For some, these medications can be life-changing. For others, they may offer little relief, cause intolerable side effects, lose effectiveness over time, or even worsen symptoms.Regardless, many individuals eventually seek to reduce or discontinue psychiatric medication use—often without adequate support. Unfortunately, most clinicians receive limited training in how to guide patients through safe, personalized tapering protocols and the existing guidelines often fail to reflect real-world experiences.In part one of our new two-part series, Dr. Bret Scher and psychiatrist Dr. Georgia Ede delve into a critical yet under-discussed topic: how to taper psychiatric medications safely.In this episode, you'll learn:Why people consider tapering (side effects, loss of benefit, life changes, etc.)Why safe psychiatric medication tapering is importantHow the brain adapts to meds (homeostasis) and how that impacts taper speedWhy personalization in medication management is importantHow to tell the difference between withdrawal and a true relapseHow to prepare: education, team support, and trusted resourcesAlmost everyone will need to adjust the dose of a medication at some point, even if only to try a different medication. Some will want to try to come off psychiatric meds entirely. It's not a journey to take alone. Safe tapering is not a DIY process. We strongly encourage working with a knowledgeable healthcare provider who can help you personalize the approach, choosing the right pace, plan, and monitoring strategies to protect your health. In addition, we recommend resources below that can help.The goal isn't simply to stop a medication, it's to feel and function at your best. And the safest route is the one that's tailored to you.

Ketogenic therapy is a powerful tool for weight loss. But not everyone who cuts carbs is able to achieve their goal weight and metabolic health goals. Could GLP-1s offer the missing piece when low-carb and clean eating aren't quite enough?In this episode of the Metabolic Mind Podcast, Dr. Bret Scher sits down with Dr. Shannon Robinson, a board-certified psychiatrist and addiction medicine specialist, to explore this overlooked population who could benefit most from GLP-1s. Drawing from both her personal journey and clinical practice, Dr. Robinson highlights why lifestyle alone isn't always enough, and how medications can sometimes be life-changing.In this conversation, you'll learn:✅ Why GLP-1s may help patients already following strict low-carb or carnivore diets✅ How keto (and GLP-1s) are beneficial for weight loss and addiction✅ The parallels between GLP-1s and addiction medicine✅ Real-world insights on side effects, dosing, and the impact of GLP-1s on muscle✅ Advice for people starting GLP-1 medications✅ Why controlling GLP-1 dose is importantFor many, food and lifestyle changes unlock better health. But when life's stressors and personal biology create roadblocks, other tools may be able to help. As Dr. Robinson highlights, GLP-1s aren't a replacement for a healthy lifestyle, but when strategically used in combination with lifestyle changes, they can be a key to success for many people.

Depression that doesn't improve, or gets labeled as treatment resistant, can leave people feeling without options and hopeless. But what if there was another way forward?In this interview, Dr. Bret Scher speaks with Silvia J. Covelli, founder and CEO of the Healing Depression Project, and Dr. Achina Stein, a board-certified psychiatrist and functional medicine physician. Together, they share how personal journeys and clinical insights converged to create a groundbreaking program that addresses depression at its root.You'll hear Silvia's story of living with depression for 25+ years before finding lasting relief through holistic lifestyle changes. And Dr. Stein explains how her own family's health crisis led her to functional psychiatry.In this conversation, you'll learn:How functional psychiatry focuses on metabolic, nutritional, and lifestyle drivers of mental health.What happens inside the Healing Depression Project retreats (labs, ketogenic therapy, , and community support).Why addressing lifestyle factors like sleep, diet, and movement can lead to depression remission, not just symptom management.How the Healing Depression Project is setting a new framework for what treating treatment resistant depression can look like.By combining functional psychiatry, metabolic therapies, and a compassionate community, this program is showing what metabolic psychiatry is all about: mental illness doesn't always have to be a lifelong sentence.

Ketogenic therapy for mental illness is gaining attention, with more and more patients looking to incorporate this strategy into their care plan.The problem is that sometimes patients struggle to find providers to help them and providers often lack the expertise and confidence to prescribe this strategy.These issues led to a light bulb moment for Dr. Kelly, “We've got to capacity build, we have to figure this out.”In this interview, Dr. Bret Scher speaks with Deanna Kelly, PharmD, internationally recognized for her work in schizophrenia, psychiatric pharmacology, and metabolic health, who is now pioneering an innovative project of her own called Live it, Launch it.This first-of-its-kind study is Dr. Kelly's brainchild, designed to train clinicians through direct experience in an effort to increase clinical expertise in metabolic and ketogenic therapies. Participants don't just learn the science, they actually live a ketogenic diet themselves, gaining confidence, competence, and practical insight to better guide patients struggling with psychiatric disorders.In this interview, you'll discover:Why so many families are searching for trained ketogenic therapy cliniciansWhy personal experience may be the missing link in clinical adoptionThe potential widespread clinical impact of Live it, Launch it.The potential of ketogenic therapy alongside medications like GLP-1sAn update on Dr. Kelly's in-patient ketogenic therapy for schizophrenia studyBy training clinicians to live it before they launch it, this study could change how psychiatric care is delivered, and help meet the growing demand for clinical guidance in ketogenic therapy.Expert Featured:Dr. Deanna KellyDirector of the Maryland Psychiatric Research CenterX: https://x.com/profdeannakResources Mentioned:Why Did the Maryland Health Department Halt a Critical Schizophrenia Study?https://youtu.be/tzPlQ6dJwe8Stanford Study Shows Promise of Ketohttps://www.metabolicmind.org/trials/featured/stanford-study-shows-promise-of-keto/Free CME Clinician Trainings:Are you a clinician who would like to learn more about the science behind these therapies and how to implement them in practice? Earn CME with our growing library of courses from some of the top experts in the field including Dr. Chris Palmer, Dr. Georgia Ede, Dr. Matthew Bernstein and Dr. Bret Scher with more coming soon.Our courses have been made FREE by grants from Baszucki Group, so we can spread these powerful therapies as widely as possible. Earn CME/CNE credits:https://www.metabolicmind.org/for-clinicians/trainings-courses/?utm_medium=organic-social&utm_source=youtube&utm_campaign=cme-ytFollow our channel for more information and education from Bret Scher, MD, FACC, including interviews with leading experts in Metabolic Psychiatry.Learn more about metabolic psychiatry and find helpful resources at https://metabolicmind.org/About us:Metabolic Mind is a non-profit initiative of...

Dr. Ryan Patel, senior staff psychiatrist at The Ohio State University, shares a practical, evidence-based roadmap for helping young adults thrive during the most turbulent years of brain and behavior development.Across this deep dive, Dr. Patel explains why 18–24-year-olds are a distinct clinical population and how day-to-day habits can make or break academic performance, quality of life, and long-term health. He also discusses his work on the KIND Trial (Ketogenic Intervention in Depression) and how those results can help to inform care.In this conversation, Dr. Patel shares:Why college students require a different clinical lensAn overview of his five high-impact interventions: sleep, nutrient-dense nutrition, physical activity, mindful tech use, and stress managementHow lifestyle factors drive anxiety, depression, and dropout risk (and how to reverse course)Practical ways campuses and clinicians can scale preventionInsights from the KIND Trial: feasibility of ketosis in students and notable mood improvementsWhen and how to consider ketogenic therapy alongside standard care for depression