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Send us Fan MailDr. Austin Dudzinski is a Clinical Pharmacist at Think Whole Person Healthcare, and enjoys working with cardiometabolic disorders, especially diabetes and dyslipidemia.Think Whole Person Healthcare partners with physicians in many areas of care, keeping primary care, specialists, and diagnostics all under the same roof, saving their patients time, emotional effort, and money.What Dr. Dudzinsky finds most exciting about working in Medicine is that there are always innovations on the horizon, especially in preventive medicine for diseases such as cancer and dementia. He has known he's wanted to work in this field since college.What Dr. Dudzinski loves most about working at think is that it provides him with the opportunity to use the entire body of knowledge that he has learned and apply it to help patients. If asked, he thinks his patients would say he's, “The bald pharmacist that calls them about their diabetes.”When he's not at work, he enjoys playing guitar, exercising, reading medical literature, and hanging out with his wife and son.Find Dr. Dudzinsky at-TW/X- @ApoDudzhttps://thinkhealthcare.org/Find Boundless Body at-myboundlessbody.comBook a session with us here!
Dave Feldman is the originator of the Lipid Energy Model and the Lean Mass Hyper-Responder (LMHR) phenotype, reshaping how we understand cholesterol and metabolism. As founder of the Citizen Science Foundation, he leads groundbreaking research into lipid metabolism, cardiovascular health, and metabolic responses to ketogenic diets. Dave's work includes spearheading the Keto-CTA study, which investigates how diet influences plaque progression and regression using advanced imaging. A passionate advocate for open science, he engages with researchers, clinicians, and the public to challenge assumptions, foster transparency, and drive innovative, data-driven insights into cardiovascular risk and human metabolism. INSTAGRAM: https://www.instagram.com/realdavefeldman TWITTER / X: https://x.com/realdavefeldman LINKEDIN: https://www.linkedin.com/in/dave-feldman/ YOUTUBE: https://www.youtube.com/@realDaveFeldman https://www.youtube.com/@feldmanprotocol Timestamps: 00:00 Trailer 00:37 Introduction 05:36 Experimenting with diet and risk decisions 08:03 Understanding the lipidary model 11:26 Early lipid conference predictions 15:56 Discussing blood glucose in athletes 17:34 Triglyceride delivery issues 21:05 Experimenting with lipid energy models 23:29 Positive feedback on keto documentary 29:42 Discrepancies in data analysis 32:51 Paper retraction and investigation process 36:47 LDL and health studies 38:33 Analyzing plaque level accuracy 41:51 Study eligibility criteria 47:29 Rethinking study design choices 48:40 The lipid hypothesis study 52:11 Metabolic health improvements 54:21 Where to watch The Cholesterol Code documentary Join Revero now to regain your health: https://revero.com/YT Revero.com is an online medical clinic for treating chronic diseases with this root-cause approach of nutrition therapy. You can get access to medical providers, personalized nutrition therapy, biomarker tracking, lab testing, ongoing clinical care, and daily coaching. You will also learn everything you need with educational videos, hundreds of recipes, and articles to make this easy for you. Join the Revero team (medical providers, etc): https://revero.com/jobs #Revero #ReveroHealth #shawnbaker #Carnivorediet #MeatHeals #AnimalBased #ZeroCarb #DietCoach #FatAdapted #Carnivore #sugarfree Disclaimer: The content on this channel is not medical advice. Please consult your healthcare provider.
Episode 2805 - Vinnie Tortorich and Anna Vocino discuss a cholesterol conundrum regarding CAC scores, numbers, and how to naturally balance those numbers. https://vinnietortorich.com/2026/05/a-cholesterol-conundrum-episode-2805 PLEASE SUPPORT OUR SPONSORS Pure Vitamin Club Pure Coffee Club NSNG® Foods VILLA CAPPELLI EAT HAPPY KITCHEN YOU CAN WATCH THIS EPISODE ON YOUTUBE - @FitnessConfidential Podcast Vinnie's workout videos are available to purchase! Choose from a 2-day, 4-day, or 6-day workout–or buy all three at a discount! TO PURCHASE VINNIE'S WORKOUT VIDEOS, CLICK THIS LINK: https://vinnietortorich.com/workout A Cholesterol Conundrum Vinnie recently posted on social media about the Women's Health Initiative. (3:00) The problem with Google is that you can "Google yourself right," so you can always find confirmation bias. There is a growing awareness of what constitutes a "clean" product. (17:00) For example, Anna's spices do not have fillers, preservatives, or anti-caking agents. Vinnie shares a story about a recent consultation. (28:00) CAC scans (calcium score test) are a great guide to see if heart disease will be an issue for you. Repatha was recommended even though the patient's numbers were great, and his calcium score was zero. Consider exploring natural supplements and lifestyle changes to manage cholesterol. The Cholesterol Code movie by Dave Feldman provides good information on cholesterol levels and the benefits of a low-carb diet. Anna goes over some bloodwork numbers and wants to discuss with her doctor. (50:00) Remember that the number ranges given in the results are representative of the general population. (52:00) It is often recommended to take CoQ10 alongside a statin. Statins deplete CoQ10, which can lead to muscle damage. Anna's products are now linked to PureVitamin Club's website. Look under the "Food and Snacks" section so that you can purchase them there, too. (58:30) https://purevitaminclub.com/collections/food-and-snacks The NSNG® VIP GROUP IS NOW CLOSED AGAIN AS OF SUNDAY, MARCH 15TH Anna's next cookbook, Eat Happy Cocktail Hour, is filled with cocktails, mocktails, and appetizers and is available for pre-order right now. If you pre-order, you'll get bonus goodies! You can preorder from a wide variety of booksellers at https://eathappycocktailhour.com/ Save your receipt from wherever you preorder, you'll need it for your bonuses! Physical Release Date is October 2026 A New Sponsor Jaspr Air Scrubbers has a discount code, VINNIE, that gets you $200 off for a limited time. Jaspr offers a lifetime warranty. Go to Jaspr.co for more information or to purchase. (1:05:00) You can book a consultation with Vinnie to get guidance on your goals. https://vinnietortorich.com/phone-consultation-2/ More News Serena has added some of her clothing suggestions and beauty product suggestions to Vinnie's Amazon Recommended Products link. Self Care, Beauty, and Grooming Products that Actually Work! https://www.amazon.com/shop/vinnietortorich/list/3GPVU29UHHPMY?ref_=aipsflist Don't forget to check out Serena Scott Thomas on Days of Our Lives on the Peacock channel. "Dirty Keto" is available on Amazon! You can purchase or rent it here.https://amzn.to/4d9agj1 Please make sure to watch, rate, and review it! Eat Happy Italian, Anna's second cookbook, is available! You can go to https://eathappyitalian.com You can order it from Vinnie's Book Club. https://amzn.to/3ucIXm Anna's recipes are in her cookbooks, on her website, and on Substack —they will spice up your day! https://annavocino.substack.com/ PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views it receives, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries
Episode 2801 - Vinnie Tortorich speaks with engineer Dave Feldman about cracking the code of cholesterol through his new documentary, The Cholesterol Code. https://vinnietortorich.com/2026/05/cracking-the-code-dave-feldman-episode-2801 PLEASE SUPPORT OUR SPONSORS Pure Vitamin Club Pure Coffee Club NSNG® Foods VILLA CAPPELLI EAT HAPPY KITCHEN YOU CAN WATCH THIS EPISODE ON YOUTUBE - @FitnessConfidential Podcast Vinnie's workout videos are available to purchase! Choose from a 2-day, 4-day, or 6-day workout–or buy all three at a discount! TO PURCHASE VINNIE'S WORKOUT VIDEOS, CLICK THIS LINK: https://vinnietortorich.com/workout Cracking the Code Dave is the creator of The Cholesterol Code documentary, which was recently released in April 2026. (3:00) Dave is an engineer and citizen scientist who has studied cholesterol for years. (5:30) It is a great documentary that addresses high cholesterol in an easy-to-follow manner. It also addresses the benefits of the ketogenic diet and how it may affect people differently. Nick Norwitz is well known for his N=1 experiment in lowering his cholesterol through a dietary regimen. (17:00) Dave explains Nick's experiment and the significance of the results. The experiment is not advocating eating junk food. It was a comparison and a data collection method. They discuss Dave's passion for doing a deep dive into cholesterol to create the documentary. (31:00) It took a while for Dave to convince others that it was a study worth doing. Lundquist and Dr. Matthew Budoff spearheaded the study. The study had 100% completion rate with 100 participants. Dr. Richard Bernstein was a T1 diabetic who decided to monitor his own blood sugar regularly and developed a system to do so. (58:00) But he was dismissed because no doctors believed people would bother to measure their own blood several times a day. But now both the study data and the documentary The Cholesterol Code are available, and people can become better educated. You can rent or purchase The Cholesterol Code here: https://amzn.to/4w7udAF Dave can be found on X as @realDaveFeldman, and at his website https://cholesterolcode.com/ The NSNG® VIP GROUP IS NOW CLOSED AGAIN AS OF SUNDAY, MARCH 15TH Anna's next cookbook, Eat Happy Cocktail Hour, is filled with cocktails, mocktails, and appetizers and is available for pre-order right now. If you pre-order, you'll get bonus goodies! You can preorder from a wide variety of booksellers at https://eathappycocktailhour.com/ Save your receipt from wherever you preorder, you'll need it for your bonuses! Physical Release Date is October 2026 A New Sponsor Jaspr Air Scrubbers has a discount code, VINNIE, that gets you $200 off for a limited time. Jaspr offers a lifetime warranty. Go to Jaspr.co for more information or to purchase. (1:05:00) You can book a consultation with Vinnie to get guidance on your goals. https://vinnietortorich.com/phone-consultation-2/ More News Serena has added some of her clothing suggestions and beauty product suggestions to Vinnie's Amazon Recommended Products link. Self Care, Beauty, and Grooming Products that Actually Work! https://www.amazon.com/shop/vinnietortorich/list/3GPVU29UHHPMY?ref_=aipsflist Don't forget to check out Serena Scott Thomas on Days of Our Lives on the Peacock channel. "Dirty Keto" is available on Amazon! You can purchase or rent it here.https://amzn.to/4d9agj1 Please make sure to watch, rate, and review it! Eat Happy Italian, Anna's second cookbook, is available! You can go to https://eathappyitalian.com You can order it from Vinnie's Book Club. https://amzn.to/3ucIXm Anna's recipes are in her cookbooks, on her website, and on Substack —they will spice up your day! https://annavocino.substack.com/ PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views it receives, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries
In this episode, I want to talk about something that confuses a lot of people: cholesterol. What it actually is, why your body needs it, and why the LDL number on your lab report doesn't tell the whole story.A new documentary that just came out in April 2026 called The Cholesterol Code got me thinking. It follows Dave Feldman, an engineer who went low-carb, stabilized his blood sugar, felt great, but then saw his LDL go up, and decided to find out why. What he discovered is turning a lot of what we thought we knew about cholesterol and heart disease upside down.Because here's the thing — what if LDL cholesterol isn't really the villain we've been told it is? What if the real problem is chronically elevated insulin?In this episode, I ask the questions:What is cholesterol? And why is it essential?What is the difference between LDL and HDL?How could sugary foods, insulin resistance, and inflammation be risk factors for heart disease?What can you ask your doctor if your cholesterol has changed since cutting sugar?Science is about asking questions, and these ones may challenge 50 years of conventional wisdom about cholesterol, statins, insulin, and heart disease.To get personalized guidance to stop emotional eating and break free from sugar cravings, plus support and accountability... apply here to join the 90-day program, Freedom from Cravings Formula TODAY.Do the Cravings Quiz and take the first step to get rid of your cravings! Struggling with cravings? Download your 5 tips HERE to discover how you can get rid of cravings... even when you feel tired or stressed.To rate and review this podcast:scroll down in your podcast player on your phone and click on the stars. To leave a review, scroll down a little more and click on "Write a Review". Once you've finished, select “Send” or “Save” in the top-right corner. If you've never left a podcast review before, enter a nickname. Your nickname will be displayed on your review.After selecting a nickname, tap OK. Your review may not be immediately visible, but it should be posted soon. Thank you! - NettaDisclaimer: Information provided by Life After Sugar is not designed to and does not provide medical advice, professional diagnosis, opinion, treatment or services to you or to any other individual. This is general information for educational purposes only. The information provided is not a substitute for medical or professional care. Life After Sugar is not liable or responsible for any advice, information, services or product you obtain through Life After Sugar. You should always seek the adv...
The Cholesterol Code is a gripping new documentary from Jennifer Isenhart that challenges one of medicine's most entrenched beliefs. Following Dave Feldman's unexpected health journey, the film dives into the controversy around cholesterol, uncovering new research and raising a powerful question: what if we've misunderstood it all along? In this episode, Dr. Tro, Jennifer, and Dave talk about… (00:00) Intro (02:39) How the upcoming documentary film, The Cholesterol Code, came to be and how Jen crafted the film to be accessible to a wide audience (08:06) How Jen turns scientific data into an engaging film (15:33) The effort and passion Dave Feldman has poured into his research (17:49) Why YOU should watch this film (Jen's answer) (22:37) How Dave went from a curious software engineer to being one of the main forces driving research on cholesterol and metabolic disease (26:24) Coining the term 'lean mass hyper-responder' and founding the Citizen Science Foundation (31:19) Dave Feldman's critics and how to push back against dogmatic medical authoritarianism (44:29) The good and the bad of cholesterol (01:00:36) LDL, ApoB, and plaque progression (01:06:36) Why YOU should watch The Cholesterol Code (Dave's answer) (01:08:06) CAC, CCTA, ApoB, and LDL levels (01:14:08) Medications that reduce arterial plaque (01:16:19) Arterial plaque and the keto diet (01:26:23) The biggest myths that were dispelled in The Cholesterol Code film (01:29:27) Medical professionals who have come around to Dave and Jen's perspective on cholesterol (01:33:32) Outro For more information, please see the links below. Thank you for listening! Links: Please consider supporting us on Patreon: https://www.lowcarbmd.com/ Resources Mentioned in this Episode: THE CHOLESTEROL CODE (documentary film): https://cholesterolcodemovie.com/the-film/ Jennifer Isenhart: The Cholesterol Code (film): https://cholesterolcodemovie.com/the-film/ Fat Fiction (film): https://fatfiction.movie/our-story Dave Feldman: The Cholesterol Code (film): https://cholesterolcodemovie.com/the-film/ Cholesterol Code (website): https://cholesterolcode.com/ X: https://x.com/realDaveFeldman Citizen Science Foundation: https://citizensciencefoundation.org/ Own Your Labs: https://ownyourlabs.com/ Dr. Brian Lenzkes: Website: https://arizonametabolichealth.com/ Twitter: https://twitter.com/BrianLenzkes?ref_src=twsrc^google|twcamp^serp|twgr^author Dr. Tro Kalayjian: Website: https://toward.health Twitter: https://twitter.com/DoctorTro IG: https://www.instagram.com/doctortro/ Toward Health App Join a growing community of individuals who are improving their metabolic health; together. Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more. Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888 Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US Learn more: https://toward.health/community/
Send us Fan MailA decade ago, Alex Klintworth and his wife Karli began studying nutrition science literature in a successful pursuit to heal their own health struggles. His engineering background has been instrumental in all aspects of his second career: Engineering in research – understanding complex systems from first principles, analyzing data, and interpreting statistics, and; Engineering in metabolic health coaching – optimizing solutions for individual goals, contexts, and human variability, and communicating vital scientific concepts to a broad audience.Alex's coaching practice focuses on empowering individuals to take an active role in their own health journey through education and collaborative decision-making. His clients regularly experience meaningful improvements in metabolic markers like blood sugar and triglycerides, but more importantly they feel energized, clear-minded, and reconnected with their bodies. Many have worked safely with their doctors to reduce or eliminate medications for conditions they once thought were permanent including diabetes, high cholesterol, anxiety, depression, and reflux.Find Alex and Karli at-https://www.hienergylife.com/Podcast and Blog- https://www.hienergylife.com/blogFind Boundless Body at-myboundlessbody.comBook a session with us here!
The UFC returns to Miami this Saturday for UFC 327, arguably the best card on paper for the organization this year. In the main event, Jiri Prochazka battles Carlos Ulberg for the vacant light heavyweight title. All things considered, who needs a victory more on Saturday night — Prochazka or Ulberg? On an all-new edition of Between the Links, the panel discusses the main event title fight on this weekend's numbered event, the stakes attached, it Alex Pereira could be persuaded to return to 205 based on who wins, and how it could all go down. Additionally, topics may include other storylines, Michael Bisping's recent comments about MMA Fighting, Mike Perry reacting to Dave Feldman, BKFC signing Darren Till, and much more. Join MMA Fighting's Mike Heck and Jed Meshew as they answer your questions all show long. Follow Mike Heck: @m_heckjr Follow Jed Meshew: @JedKMeshew Subscribe: http://goo.gl/dYpsgH Check out our full video catalog: http://goo.gl/u8VvLi Visit our playlists: http://goo.gl/eFhsvM Like MMAF on Facebook: http://goo.gl/uhdg7Z Follow on Twitter: http://goo.gl/nOATUI Read More: http://www.mmafighting.com Learn more about your ad choices. Visit podcastchoices.com/adchoices
The UFC returns to Miami this Saturday for UFC 327, arguably the best card on paper for the organization this year. In the main event, Jiri Prochazka battles Carlos Ulberg for the vacant light heavyweight title. All things considered, who needs a victory more on Saturday night — Prochazka or Ulberg? On an all-new edition of Between the Links, the panel discusses the main event title fight on this weekend's numbered event, the stakes attached, it Alex Pereira could be persuaded to return to 205 based on who wins, and how it could all go down. Additionally, topics may include other storylines, Michael Bisping's recent comments about MMA Fighting, Mike Perry reacting to Dave Feldman, BKFC signing Darren Till, and much more. Join MMA Fighting's Mike Heck and Jed Meshew as they answer your questions all show long. Follow Mike Heck: @m_heckjr Follow Jed Meshew: @JedKMeshew Subscribe: http://goo.gl/dYpsgH Check out our full video catalog: http://goo.gl/u8VvLi Visit our playlists: http://goo.gl/eFhsvM Like MMAF on Facebook: http://goo.gl/uhdg7Z Follow on Twitter: http://goo.gl/nOATUI Read More: http://www.mmafighting.com Learn more about your ad choices. Visit podcastchoices.com/adchoices
The UFC returns to Miami this Saturday for UFC 327, arguably the best card on paper for the organization this year. In the main event, Jiri Prochazka battles Carlos Ulberg for the vacant light heavyweight title. All things considered, who needs a victory more on Saturday night — Prochazka or Ulberg? On an all-new edition of Between the Links, the panel discusses the main event title fight on this weekend's numbered event, the stakes attached, it Alex Pereira could be persuaded to return to 205 based on who wins, and how it could all go down. Additionally, topics may include other storylines, Michael Bisping's recent comments about MMA Fighting, Mike Perry reacting to Dave Feldman, BKFC signing Darren Till, and much more. Join MMA Fighting's Mike Heck and Jed Meshew as they answer your questions all show long. Follow Mike Heck: @m_heckjr Follow Jed Meshew: @JedKMeshew Subscribe: http://goo.gl/dYpsgH Check out our full video catalog: http://goo.gl/u8VvLi Visit our playlists: http://goo.gl/eFhsvM Like MMAF on Facebook: http://goo.gl/uhdg7Z Follow on Twitter: http://goo.gl/nOATUI Read More: http://www.mmafighting.com Learn more about your ad choices. Visit podcastchoices.com/adchoices
Dave Feldman, a software engineer turned citizen scientist, went on a ketogenic diet and watched his LDL cholesterol spike dramatically while his family members on the same diet saw no such change. Unable to get cardiologists or lipidologists to study the phenomenon, he built a public charity from scratch, crowdfunded the research, and designed the Keto CTA study — enrolling 100 metabolically healthy people with very high LDL and scanning their coronary arteries with CT angiograms at baseline and one year later. He filmed the entire process. The result is the documentary The Cholesterol Code.The findings were notable, but the story became more complicated when the AI-assisted plaque analysis from the company Cleerly produced results Feldman considered statistically anomalous — including zero regressors across 99 participants, and greater plaque progression in people with a calcium score of zero than in those with a positive score, which contradicts established research. Dave Feldman Contact InfoThe Cholesterol Code Movie: https://cholesterolcodemovie.com/Citizen Science Foundation Website: https://CitizenScienceFoundation.org: Cholesterol Code Website: https://cholesterolcode.com/Send Dr. Ovadia a Text Message. (If you want a response, you must include your contact information.) Dr. Ovadia cannot respond here. To contact his team, please send an email to team@ifixhearts.com Pre-Order Stay Off My Kitchen Table at Amazon. Like what you hear? Head over to IFixHearts.com/book to grab a copy of my book, Stay Off My Operating Table. Ready to go deeper? Talk to someone from my team at IFixHearts.com/talk.Stay Off My Operating Table on X: Dr. Ovadia: @iFixHeartsJack Heald: @JackHeald5Learn more:Stay Off My Operating Table on AmazonTake Dr. Ovadia's metabolic health quiz: iFixHearts Dr. Ovadia's website: Ovadia Heart HealthJack Heald's website: CultYourBrand.comTheme Song : Rage AgainstWritten & Performed by Logan Gritton & Colin Gailey(c) 2016 Mercury Retro RecordingsAny use of this intellectual property for text and data mining or computational analysis including as training material for artificial intelligence systems is strictly prohibited without express written consent from Dr. Philip Ovadia.
A new documentary exploring one of the most debated topics in metabolic health—the rise in LDL cholesterol sometimes seen in people following low-carbohydrate diets—is beginning its global rollout. In this episode of the LowCarbUSA® Podcast, I spoke with independent researcher Dave Feldman about his new documentary, The Cholesterol Code, which chronicles his research and the ongoing debate surrounding cholesterol and metabolic health. The movie is being premiered between March 15 and April 15 through multiple theatrical screenings around the world. "If you don't see one in your community, then sign up to host your own screening in your area. Dave, an engineer by training who became widely known in the low-carb community through his self-experiments and data-driven investigations, described how the project began with a personal question. "I'm the engineer who started obsessing about his cholesterol when it went sky high on a keto diet," he said. "Then came about a lot of my self-experiments, which ultimately led to forming the lipid energy model, which is now published." That model attempts to explain why some people—particularly those who are lean and metabolically healthy—experience unusually high LDL cholesterol levels when following a ketogenic or very low-carbohydrate diet. These individuals are known as lean mass hyper-responders, a term Feldman coined to describe people who exhibit a distinctive metabolic pattern: very high LDL cholesterol, high HDL cholesterol, and very low triglycerides. Investigating the Risk Question While the metabolic explanation for the phenomenon has attracted growing attention, Dave said the larger and more pressing question has always been risk. "How much does the risk of going on a keto diet and then seeing your LDL go up— even if it is for these reasons—actually matter?" he said. "How much could this develop what's known as atherosclerosis, the building up of plaque in the arteries?" To explore that question, he launched a crowdfunded research effort through the Citizen Science Foundation. The study recruited 100 individuals identified as lean mass hyper-responders. Participants underwent advanced heart imaging using CT angiography at the Lundquist Institute, allowing researchers to measure plaque in the coronary arteries. "They get a baseline scan, and then one year later they get a follow-up scan," he explained. "That way we can see the changes of plaque over time—not just individually, but also at a population level." From Research Project to Documentary The documentary The Cholesterol Code captures the unfolding story of that research. According to Dave, filmmaker Jen Eisenhart began documenting the project shortly after the first baseline scan data became available. "They started filming and managed to capture all of this," he said. "It's a riveting story and it all comes together in this film." The documentary follows not only the scientific investigation but also the real-world experiences of people who adopted low-carbohydrate diets for serious medical conditions Many participants, he said, had experienced life-changing improvements—only to later face anxiety when routine blood tests showed rising LDL cholesterol levels. "They see their cholesterol go up and they go, 'Is this actually worth it?'" Dave said. "Even if I really respond well to a low-carb diet—even if I'm doing great—my cholesterol goes up. What does that mean?" The film includes interviews with individuals managing conditions such as type 1 diabetes, bipolar disorder, eating disorders, and inflammatory bowel disease. Their stories are really touching, hats off to Jen Eisenhart and her team. It's such a great film. I feel those stories were among the most powerful moments in the film. One of the mental-health stories, particularly, just ripped my heart out. She got her life back. She got her children back. And then she was agonizing about whether she should stop because her LDL was going up. Research Complications and Scientific Debate The research itself has also drawn attention because of an unexpected analytical complication that arose during the study. Dave explains that a secondary analysis conducted using artificial intelligence–guided plaque imaging software produced results that differed from other analyses of the same scans. "Three of those analyses disagree with this one," he says. "On top of that, the company that provides that analysis won't do a quality control check." As a result, the research team has requested retraction of the paper associated with that analysis while further investigation continues. "That development ultimately strengthened the documentary by extending filming and allowing additional analysis and interviews to be incorporated. The neat thing is this delay did give us a chance to tighten up the movie more." Community-Driven Film Screenings The film is now being released through a community-driven screening model. Viewers can organize or attend screenings through the film's website, which uses a platform that allows communities to request theatrical showings once a minimum number of tickets are reserved. "If they go to the website, that's where they can either join an existing screening—of which there are now many across the United States and actually across the world—or they can host their own," Dave said. I really encourage listeners to participate. If you don't see one in your community, then sign up to host a screening and try to activate your community. Continuing Research Beyond the documentary, Dave said the work is continuing with additional research initiatives. One upcoming project—currently referred to as the Triad Study—aims to further investigate the metabolic patterns associated with lean mass hyper-responders and their cardiovascular implications. "We're hoping to close funding on our companion research study,"he said. "The numbers are looking pretty good." As debate continues about the role of cholesterol in metabolic health—particularly among people following carbohydrate-restricted diets—Dave believes the conversation must remain grounded in data and open scientific inquiry. For many viewers, the documentary offers both a scientific investigation and a human story about the intersection of metabolic health, medical uncertainty, and personal transformation. "It's a great film and it tells a story that a lot of people in this community are living right now."
What if everything your doctor told you about cholesterol is based on corrupted science? In this episode of the Gut Check Project, Dr. Kenneth Brown and Eric Rieger dive deep into the emerging world of Lean Mass Hyper Responders (LMHR) - metabolically healthy people on ketogenic and carnivore diets whose LDL numbers look alarming on paper but may tell a completely different story in real life.They break down a groundbreaking citizen-science study led by Dave Feldman and Dr. Nick Noritz that's challenging decades of lipid orthodoxy, explore why high LDL + high HDL + low triglycerides may not be the death sentence mainstream medicine makes it out to be, and share the story of a 53-year-old marathon runner with "normal" cholesterol who still ended up in the cath lab.If you or someone you love has been told to go on statins, this episode is required listening.Topics covered:The LMHR phenotype and what it means for keto/carnivore dietersWhy Ansel Keys and the sugar industry shaped a generation of bad dietary advicePlaque progression, inflammatory markers (hs-CRP), and what actually predicts heart diseaseWhy the Clearly AI cardiac scan study raised more questions than answersThe difference between dangerous cholesterol and protective cholesterol
Send a textThis amazing episode also includes a special guest, Dr. Leslyn Keith!Siobhan Huggins is a returning guest on our show! Be sure to check out her first appearance on episode 656 of Boundless Body Radio!Siobhan Huggins is an independent researcher with interests in cholesterol metabolism, inflammation, lipedema, and metabolic diseases. After meeting former podcast guest Dave Feldman at Ketofest 2017, Siobhan's passion for lipidology was ignited and she was driven to research all she could in an attempt to figure out how lipids were involved in the immune system and chronic diseases.After losing over 80 pounds, she referred to a lipedema specialist for a possible diagnosis, which sparked her interest in the condition as a whole and the people it affects every day. She was finally diagnosed with lipedema in 2021, and she promptly joined the board of the Lipedema Project as a Research Specialist.She presents at various conferences on lipedema pathophysiology and the mechanisms of why ketogenic diets may be uniquely beneficial for managing lipedema symptoms and progression. She has since written several published articles on many platforms, including on Dave Feldman's Cholesterol Code website.Event- Kind & Gentle Low-Carb Nutrition for Holistic Healing in Lipedema & Lymphedema: A Heart to Heart Virtual Event, April 17-19, 2026Find Siobhan at-https://lipedemaproject.org/https://lipedema-simplified.org/TW- @siohban_hugginshttps://ownyourlabs.com/Find Dr. Leslyn Keith at-Email- leslyn@lipedemaproject.orghttps://www.leslynkeith.com/https://lipedema-simplified.org/Book- The Lymphatic CodeFind Boundless Body at- myboundlessbody.com Book a session with us here!
We just wrapped up a quick episode of The Work. We had a bit of a late start because I was finishing up at the accountant's office—dealing with that usual year-end and beginning-of-the-year paperwork.I'm really leaning into the data right now. I'm planning to fly to Vegas the second week of March to be on Dave Feldman's podcast, so I want to have a fully comprehensive lab panel and Dexa scan done before then. I want to see what my markers look like specifically in the context of my current body fat. It's wild how much an influx of food and higher body fat can swing your lipid panels; I've seen my total cholesterol hit 400 in a surplus and then drop back to 200 once I returned to baseline.I've pivoted away from the fiber experiment because the inflammation was up and I just wasn't enjoying the food. Now, I'm doing a One Meal a Day (OMAD) approach. It's a tangible way for me to keep the reins on my total consumption while still feeling completely satiated—like a "lion eating a gazelle." My routine is heavy cream in my coffee during the day, followed by one large 2,500–3,000 calorie meal in the evening. After that meal, I'll take the kids to the gym and walk laps with the stroller to keep my blood sugar stable. I'm even going to grab an over-the-counter CGM (the Lingo) to track exactly how those meals and the post-meal movement impact my levels.We spent some time talking about the "shredded year-round" trap. If you're a natural lifter and you actually want to make progress from season to season, you have to allow yourself a legitimate building phase with higher body fat. Bragging about abs year-round doesn't mean much if you have no legs, no strength, and your hormones are trashed. You've got to give yourself time in a surplus if you want to put on substantial tissue.Tough Mudder: We're heading out next Friday with a crew of 10 or 12 people. We've got a massive Airbnb booked and I'm planning a build-your-own shish kebab night for everyone.Bacon & Bullets: We're getting ready to process our pigs soon. I want to have a big team day where we roast half a pig, shoot some guns, and make some cracklings.Show Prep: We've been driving around sticking up posters at local gyms to get people registered for the upcoming show.Giveaway: Congrats to Joyce, the winner of our $6,500 Carnivore Convenience collab bundle. She's set on groceries for a long time.We've got something huge in the pipeline that we aren't ready to talk about yet, but we'll dive into that on the next one.Greg Mahler is also a lifetime natural bodybuilder, and can be followed on Instagramhttps://www.instagram.com/ketogreg80/Register For My FREE Masterclass: https://www.ketobodybuilding.com/registration-2Get Keto Brick: https://www.ketobrick.com/Subscribe to the podcast: https://open.spotify.com/show/42cjJssghqD01bdWBxRYEg?si=1XYKmPXmR4eKw2O9gGCEuQ
Episode 2756- Vinnie Tortorich and Chris Shaffer welcome two callers to discuss health, doing your research, and how to avoid a rigid mindset. https://vinnietortorich.com/2026/01/avoid-a-rigid-mindset-episode-2756 PLEASE SUPPORT OUR SPONSORS Pure Vitamin Club Pure Coffee Club NSNG® Foods VILLA CAPPELLI EAT HAPPY KITCHEN YOU CAN WATCH THIS EPISODE ON YOUTUBE - @FitnessConfidential Podcast Vinnie's workout videos are available to purchase! Choose from a 2-day, 4-day, or 6-day workout–or buy all three at a discount! TO PURCHASE VINNIE'S WORKOUT VIDEOS, CLICK THIS LINK: workout videos. Avoid a Rigid Mindset Moe is the first guest. (3:00) He loves mountain biking, trains for the Leadville 100, and has questions about training for it. Howie is the next caller. (20:00) First, a little chat about Canada. Howie started NSNG, and it worked great. (28:00) He had a consult with Vinnie because he felt he had plateaued and even started gaining some weight back. His LDLc skyrocketed, so he has questions and did his own research. Lean Mass Hyper Responders are people whose cholesterol levels respond differently to a low-carb diet. Dave Feldman is leading the research. at Cholesterol Code. He reduced his food intake and made minor adjustments, and his weight began to drop again. It's always good to do your own thorough research and avoid a rigid mindset so you can continue learning. (39:00) Did you miss it?: The NSNG® VIP group closed, but you can get onto the waitlist for next time by signing up at https://www.nsngvip.com/join. A New Sponsor Jaspr Air Scrubbers has a discount code, VINNIE, that gets you $300 off for a limited time. Jaspr offers a lifetime warranty. Go to Jaspr.co for more information or to purchase. (1:05:00) You can book a consultation with Vinnie to get guidance on your goals. https://vinnietortorich.com/phone-consultation-2/ More News Serena has added some of her clothing suggestions and beauty product suggestions to Vinnie's Amazon Recommended Products link. Self Care, Beauty, and Grooming Products that Actually Work! Don't forget to check out Serena Scott Thomas on Days of Our Lives on the Peacock channel. "Dirty Keto" is available on Amazon! You can purchase or rent it here.https://amzn.to/4d9agj1 Please make sure to watch, rate, and review it! Eat Happy Italian, Anna's next cookbook, is available! You can go to https://eathappyitalian.com You can order it from Vinnie's Book Club. https://amzn.to/3ucIXm Anna's recipes are in her cookbooks, on her website, and on Substack —they will spice up your day! https://annavocino.substack.com/ PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views it receives, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere: https://vinnietortorich.com/documentaries
When Dave Feldman first walked into a LowCarbUSA® event in 2016 carrying a laptop full of lab results, few people could have predicted where that moment would lead. "I'm approaching everyone with my computer," Feldman recalls, "because I'm doing these self-experiments—getting blood work—and I'm trying to figure out why my cholesterol numbers were doing what they were doing." What started as a personal puzzle became The Cholesterol Code, a global research effort, a nonprofit scientific foundation, and now a forthcoming documentary film. In this episode of the LowCarbUSA Podcast, host Doug Reynolds sits down with Feldman to trace that journey—and to explain why the next chapter will take center stage at the Symposium for Metabolic Health in Boca Raton, January 23–25, 2026 The Question That Wouldn't Go Away Dave's original question was deceptively simple: Why do some metabolically healthy, lean people see their LDL cholesterol rise dramatically on a ketogenic diet? Over time, he noticed a consistent pattern. These individuals didn't just have high LDL—they also tended to have high HDL, low triglycerides, and excellent metabolic health. In 2017, he coined a name for this group: Lean Mass Hyper-Responders (LMHRs). But identifying a pattern wasn't enough. "Even if the lipid energy model proves correct," Dave explains, "does that mean having higher LDL on a ketogenic diet carries higher cardiovascular risk?" Answering that question required something far more difficult than a blog post or a hypothesis: a prospective imaging study. Building a Study When No One Will Fund One Dave spent years trying—and failing—to convince established institutions to study this population. "There's not a lot of funding to study metabolically healthy people with sky-high LDL," he says dryly. "The interest is usually in people who already have multiple cardiovascular risk factors—which confounds everything." So in 2019, he made a radical decision. He founded the Citizen Science Foundation, a public charity created for a single purpose: to fund independent research, with no money going to salaries or overhead. "We raised $200,000,"Dave says, "and paid a research center to do the study." By late 2021, recruitment was underway. One hundred lean, metabolically healthy ketogenic individuals underwent coronary CT angiography (CTA) scans to assess plaque in their coronary arteries, with follow-up scans roughly one year later. What the Data Actually Showed The early findings were striking. When Dave's cohort was matched against participants from the Miami Heart Study, there was no statistically significant difference in coronary plaque, despite Dave's group having LDL levels less than twice as high. "In fact," he notes, "our group trended toward lower plaque." But the most important finding emerged as more analyses were completed: "There was no association between ApoB or LDL and plaque progression," Dave says. "Whatever your LDL level was, it did not correspond with how plaque developed." What did matter? Baseline plaque. "Whether you're low-carb or not," he explains, "the more plaque you have at baseline, the more likely you are to see progression. That's consistent with the existing literature." When One Dataset Didn't Make Sense Then came the controversy. An AI-based quantitative analysis from a company called Cleerly showed plaque progression that appeared inconsistent—not only with Dave's other data, but with decades of prior research. "All of the scans showed progression," he says. "No regression. Not even noise." For an engineer, that raised immediate red flags. "If a bathroom scale is off by a quarter pound," Dave explains, "you expect wobble. Below the noise floor, measurements go up and down. But this dataset showed only one direction." Later, when Dave gained access to the anonymized data, he identified multiple anomalies and requested a blinded quality-control reanalysis. That request was declined. "I don't assume wrongdoing," he emphasizes. "But when something looks implausible, the response should be course correction." Instead, he sought independent confirmation. A second AI company, HeartFlow, conducted a fully blinded analysis—and its results aligned with every other analysis except Cleerly's. "Three out of four analyses agree," he says. "Cleerly is the outlier." Why This Matters Beyond One Study The implications extend far beyond a single dataset. Dave believes this episode exposes a deeper issue in nutrition and cardiovascular science: how dominant theories shape interpretation. "The lipid hypothesis has a gravitational pull," he says. "It affects what people expect to see—and what they question." As I put it, Dave has repeatedly taken the LowCarbUSA stage to announce findings that challenge assumptions—and each time, the conversation moves forward. "If we want better answers," Dave says, "we have to do better science." The Documentary—and What Comes Next All of this has reshaped his upcoming documentary, The Cholesterol Code. Originally slated for release last year, the film has been expanded to include the scientific and human story behind these findings. "We couldn't release it without covering what happened," he explains. "It's part of the truth." For the first time anywhere, the official trailer for the film will be shown at the LowCarbUSA Symposium in Boca, immediately following Dave's talk. Attendees will also be invited to help bring the film to live screenings around the world. "The world premiere of the trailer will be at your conference," Dave told me. "That alone is worth coming for." Why You'll Want to Be There One full day of the Boca symposium is dedicated to cardiovascular health, and Dave is one of the central voices shaping that conversation. Whether you attend in person or via live stream, this is a rare opportunity to engage directly with research that is still unfolding—and with the scientist who helped drive it. As Dave puts it: "The work just needs to get done, and in Boca, it will." Learn more and reserve your in-person or virtual seat for the Boca Symposium for Metabolic Health (January 23–25, 2026)
The Truth About Cholesterol, LDL, and Plaque Regression with Dave Feldman | Lean Mass Hyper-Responder Research Explained What if everything you've been told about cholesterol and heart disease is incomplete — or even wrong? In this eye-opening episode of The Coach Debbie Potts Show, I sit down with Dave Feldman, engineer turned citizen scientist, founder of Own Your Labs and The Citizen Science Foundation, and the mind behind the Lean Mass Hyper-Responder (LMHR) study and the groundbreaking Keto-CTA trial on plaque progression and regression. We unpack the latest findings from Dave's multi-platform coronary imaging study — comparing HeartFlow, QAngio, Cleerly, and expert readouts — to explore how some individuals with very high LDL cholesterol and low inflammation show no increase in plaque and, in some cases, true regression. You'll learn:
The Real Truth About Cholesterol, Heart Disease & Cardiovascular Health SUMMARY What if your cholesterol isn't trying to kill you—it's trying to protect you? In this solo deep-dive, Coach Debbie Potts breaks down the outdated cholesterol myths and reveals the root-cause truth behind cardiovascular disease. Drawing from the work of Dave Feldman, Dr. Ben Bikman, Dr. Paul Mason, Ivor Cummins, and Dr. William Davis, Debbie explains why heart disease is an inflammatory, metabolic, and endothelial problem—not a cholesterol problem. Learn which markers truly predict risk, how to interpret your labs beyond LDL, the role of genetics and epigenetics, and what it really takes to reverse plaque and rebuild a resilient metabolism. If you're ready to move beyond fear and finally understand your cardiovascular health through the lens of functional, ancestral, and root-cause medicine, this episode is your roadmap. KEY TAKEAWAYS LDL isn't "bad"—oxidized, inflamed LDL in a damaged arterial wall is. Heart disease = terrain dysfunction: insulin resistance, oxidative stress, mitochondrial damage, and loss of nitric oxide. ApoB + inflammation predict risk far better than total cholesterol. Context matters: High LDL in a low-inflammation, insulin-sensitive body ≠ the same risk as in a high-inflammation body. Saturated fat isn't the enemy; oxidized seed oils and sugar are. You can't out-supplement poor habits. Sleep, stress regulation, circadian alignment, and daily movement build vascular resilience. Plaque can stabilize or regress when you heal the root causes. The WHOLESTIC Method™ integrates nutrition, movement, sleep, stress, digestion, hydration, and happiness to rebuild your health from the inside out. TESTS & TOOLS MENTIONED - talk to your provider! ApoB (< 80 mg/dL optimal) LDL-P (< 1,000 nmol/L) Triglyceride : HDL ratio (< 1) hs-CRP (< 0.5 mg/L) Lp(a) (< 30 mg/dL) Fasting Insulin / HOMA-IR (< 5 µIU/mL / < 1.0) Coronary Artery Calcium (CAC) Score (0 = clean) CCTA / Cleerly AI Analysis for plaque composition Carotid IMT, Omega-3 Index, Homocysteine, Vitamin D + K2
When someone's LDL cholesterol hits 574 mg/dL, doctors typically expect the worst. But what if everything we think we know about cholesterol and heart disease risk is incomplete?In this episode, I sit down with researchers Nick Norwitz, Adrian Soto-Mota, and Dave Feldman to discuss their groundbreaking study on lean mass hyperresponders - a rare population who develop extremely high LDL cholesterol on ketogenic diets despite being lean, fit, and metabolically healthy. Their recent paper "Plaque Begets Plaque, ApoB Does Not" challenges conventional wisdom by showing that in this unique population, neither LDL cholesterol nor ApoB levels predicted plaque progression over one year of follow-up. Instead, existing plaque was the strongest predictor of future plaque growth. We explore the proposed lipid energy model that may explain why some people's cholesterol skyrockets on keto, discuss the limitations and implications of their findings, and examine what this means for personalized cardiovascular risk assessment. This conversation touches on fundamental questions about causality in medicine, the importance of studying outlier populations, and why a one-size-fits-all approach to cholesterol management may be missing crucial nuances.
Stephen Thomas interviews Dave Feldman about his recent study on near-lean mass hypersponders and the implications of high LDL cholesterol levels. They discuss the study's methodology, key findings, and address criticisms regarding the narrow participant range and the use of contrast dye in scans. The conversation also explores the relationship between LDL levels, health markers, and lifestyle factors that may contribute to plaque regression. Feldman emphasizes the importance of understanding the context of health markers and the need for further research in this area.Chapters00:00 Introduction to the Keto CTA Study06:55 Key Findings from the Study11:36 Critiques and Limitations of the Study16:01 The Role of Contrast Dye in Scans19:59 Understanding Regression in Plaque27:08 The LDL Dilemma and Metabolic Health37:51 Future Directions and Closing Thoughts
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Send us a textDarius Shapre is a returning guest on our show! Be sure to check out his first appearance on episode 636 of Boundless Body Radio! Darius Sharpe has an extensive 22-year career in healthcare, including 3 years as an EMT, 13 years as a paramedic, and 6 years as an ER nurse. He is a dedicated fitness and health enthusiast, regularly participating in endurance events such as Spartan Races and marathons.Despite maintaining good health, he was diagnosed as pre-diabetic some years ago and discovered a CAC score of 44 at the age of 39 in the summer of 2023. Since then, he has devoted significant effort to understanding the reasons behind these health issues and determining the appropriate course of action.Darius has become increasingly dissatisfied with the current medical system and has questioned why doctors do not prescribe nutrition and exercise plans to patients instead of solely relying on medication. Drawing on his medical background, Darius has delved deeply into the realms of nutrition, metabolic illness, diabetes, cardiac disease, and autoimmunity.He continues to educate himself daily and has been amazed to discover in the literature how many of these conditions can be prevented, reversed, or improved through simple dietary changes.Find Darius at-IG- @murse_dariusTW- @MurseDariusFB- Darius Sharpehttps://cosci.org/Find Boundless Body at- myboundlessbody.com Book a session with us here!
I dag har vi med oss den kloke og kunnskapsrike Anders Haakenstad – coach, tidligere gründer og en engasjert stemme i helse- og kostholdsdebatten. Du har kanskje sett han på Instagram, hørt han i andre podcaster og engasjementet hans i kreftdebatten. I dag dykker vi dypt ned i noe av det mest kontroversielle innen helsefeltet: kolesterol.Vi stiller spørsmål som:Hva er egentlig kolesterol – og hvorfor har det fått et så dårlig rykte?Er høyt kolesterol en sykdom, eller et symptom?Hva betyr det når kolesterolet stiger på keto eller lavkarbo?Hvordan bør vi egentlig tolke blodprøver?Er statiner alltid svaret – eller finnes det alternativer?
So, your cholesterol is high? The big question my guest today is asking is - does it even matter? Why this does matter so much is because Dave Feldman and his network of researchers are asking a fundamentally new question about cholesterol and lipids, and whether they are in fact energy adaptogens, responsible for trafficking energy under the right conditions around the body and not predictable of cardiovascular disease. Because if Oreos can lower your “bad” cholesterol as much as a statin, medicine may not actually understand “bad” cholesterol or even cholesterol overall.Dave Feldman, a senior software engineer and entrepreneur. Drawing on his engineering background, he recognized parallels between the lipid system and distributed objects in networks, prompting him to delve deeply into the subject through extensive research and personal experimentation. He is also the creator and producer of his new film The Cholesterol Code, coming up in the fall of 2025: https://cholesterolcodemovie.comJoin us as we explore:A completely contrary and potentially revolutionary lens for understanding cholesterol levels, lipids as an energy model and what actually drives cardiovascular disease.Why the “saturation hypothesis” is asking new questions about the relevance of apolipoprotein b.The lean mass hyper responder - who they are, how to identify them, what it is, why it matters and how Nick Norwitz used Oreos to lower his LDL better than pharmaceutical statins.The most important biometric data points aside from cholesterol that signals cardiovascular health risk.Contact: Website: https://cholesterolcode.comMention: Person - Nick Norwitz, @nicknorwitzPhD Study - Plaque Begets Plaque, ApoB Does Not: Longitudinal Data From the KETO-CTA Trial. https://pubmed.ncbi.nlm.nih.gov/40192608/Study - Oreo cookies, Norwitz NG, Cromwell WC. Oreo Cookie Treatment Lowers LDL Cholesterol: https://pubmed.ncbi.nlm.nih.gov/38276308/Study - Danish study: Association of Coronary Plaque With Low-Density Lipoprotein Cholesterol Levels and Rates of Cardiovascular Disease Events Among Symptomatic Adults. https://findresearcher.sdu.dk/ws/portalfiles/portal/199250545/Open_Access_Version.pdfProduct - CLEERLY, https://cleerlyhealth.comPerson - Matthew Budoff, https://lundquist.org/matthew-budoff-md Support the showFollow Steve's socials: Instagram | LinkedIn | YouTube | Facebook | Twitter | TikTokSupport the show on Patreon:As much as we love doing it, there are costs involved and any contribution will allow us to keep going and keep finding the best guests in the world to share their health expertise with you. I'd be grateful and feel so blessed by your support: https://www.patreon.com/MadeToThriveShowSend me a WhatsApp to +27 64 871 0308. Disclaimer: Please see the link for our disclaimer policy for all of our content: https://madetothrive.co.za/terms-and-conditions-and-privacy-policy/
The Mighty Manfred's guest this week is Dave Feldman of Wyldlife. “Shotgun” is our Coolest Song in the World this week! Join the Mighty Manfred and Dave Feldman for this week's Coolest Conversation, presented by Hard Rock
Send us a textDr. Adrian Soto-Mota is a returning guest on our show! Be sure to check out episode 138 of Boundles Body Radio, which was part of a special series we did, featuring Dr. Nick Norwitz as the guest host!We also hosted Dr. Soto-Mota on episode 340, episode 419, and episode 599 of our show!Dr. Soto-Mota is a MD PhD & Specialist in Internal Medicine and Data Science researcher at the Unidad de Investigación de Emfermedades Metabólicas! Dr. Soto-Mota is passionate about studying low carbohydrate and ketogenic diets, and how they impact human metabolism.Dr. Soto-Mota earned his MD from the Universidad Nacional Autónoma de México, and earned his Ph.D. at Oxford. He has created many resources to help people successfully implement a low carbohydrate diet, and provides that help for both English and Spanish speaking individuals.He is the co-author of a 2022 paper titled The Lipid Energy Model: Reimagining Lipoprotein Function in the Context of Carbohydrate-Restricted Diets, and the co-author of the recent paper titled Plaque Begets Plaque, ApoB Does Not: Longitudinal Data From the KETO-CTA Trial- JACC Journal April 7, 2025, both of which were also co-authored by former guests Dr. Norwitz and Dave Feldman, who we hosted in episode 109 of Boundless Body Radio!Find Dr. Soto-Mota at-TW- @AdrianSotoMotaPlaque Begets Plaque, ApoB Does Not: Longitudinal Data From the KETO-CTA Trial- JACC Journal April 7, 2025Keto Cholesterol study SHOCKS scientific community | LMHRs & heart disease from the Nutrition Made Simple YouTube ChannelAnalyzing the KETO-CTA Study with Dr. Gil Carvalho 813 on Boundless Body Radio!Discussing Keto-CTA with Darius Sharpe with Dave Feldman and Darius SharpeFind Boundless Body at- myboundlessbody.com Book a session with us here!
Stephen Thomas interviews Dave Feldman about his recent research on lean mass hyper responders and the implications of high LDL cholesterol levels in relation to cardiovascular health. They discuss the purpose of the study, the challenges faced in its design, and the community's reactions to the findings. Feldman emphasizes the importance of understanding the relationship between plaque progression and cholesterol levels, while also addressing critiques and misunderstandings surrounding the study. The conversation concludes with a focus on future research directions and the role of community support in advancing scientific inquiry.Chapters00:00 Introduction and Background03:01 The Purpose of the Study05:57 Study Design and Methodology08:46 Findings and Controversies12:04 Understanding Plaque and LDL14:50 Critiques and Community Reactions18:02 Future Directions and Next Steps
Send us a textGil Carvalho, MD is a physician, research scientist, science communicator, speaker and writer. Dr. Carvalho trained as a medical doctor in the University of Lisbon, in his native Portugal, and later obtained a PhD in Biology from Caltech. He has published peer-reviewed medical research spanning the fields of genetics, molecular biology, nutrition, behavior, aging and neuroscience.In parallel with his research career, Dr. Carvalho also has a passion for science communication. He directs and hosts Nutrition Made Simple, which aims to convey fundamental nutrition concepts to a general audience via educational videos, and his content is watched by over half a million people monthly.Dr. Carvalho's research contributions at Caltech, where he trained with pioneer geneticist Seymour Benzer, included the identification of genetic and nutritional mechanisms of longevity. Dr. Carvalho also pursued research, with neuroscientist Antonio Damasio, on mechanisms of neural signal transmission in the sensory system and the neural basis of enteroception and feeling.Find Dr. Carvalho at-YT- @NutritionMadeSimpleTW- @NutritionMadeS3Plaque Begets Plaque, ApoB Does Not: Longitudinal Data From the KETO-CTA Trial- JACC Journal April 7, 2025Keto Cholesterol study SHOCKS scientific community | LMHRs & heart disease from the Nutrition Made Simple YouTube ChannelDiscussing Keto-CTA with Darius Sharpe with Dave Feldman and Darius SharpeFind Boundless Body at- myboundlessbody.com Book a session with us here!
What if everything we thought we knew about cholesterol and heart disease risk… doesn't apply to everyone?In this episode, world-renowned cardiologist Dr. Matthew Budoff unpacks the results of a landmark one-year study tracking 100 lean, metabolically healthy individuals on a ketogenic diet with extremely elevated LDL levels.Dr. Budoff is the Program Director, Director of Cardiac CT, and the endowed chair of preventive cardiology at The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center.In this interview, Dr. Scher and Dr. Budoff further break down the results of his new publication, which used advanced imaging to demonstrate that LDL cholesterol and ApoB levels are not associated with plaque progression in Lean-Mass Hyper Responders following a ketogenic diet.
Is LDL cholesterol the best way to measure and predict heart disease?New research suggests no!Dave Feldman is an engineer turned citizen scientist who has devoted his life to understanding a phenomenon that some individuals around the world are experiencing: a robust increase in LDL cholesterol while on a ketogenic diet.Dave's past research has identified a unique phenotype dubbed Lean Mass Hyper-Responders (LMHRs). LMHRs respond to ketogenic therapy with a metabolic profile that includes elevated LDL-C and ApoB levels with otherwise healthy metabolic markers, including low triglycerides, high HDL, low blood pressure, low insulin resistance, and low BMI.In Dave's most recent publication, what most doctors would consider dangerously high LDL levels in LMHRs did not correlate with an increased risk of heart disease.In this video, Dr. Bret Scher sits down with Dave Feldman to discuss this groundbreaking study and its implications for ketogenic therapy and cardiology.Key Takeaways:LMHRs on a long-term ketogenic diet who show elevated LDL can show robust metabolic healthLDL-C and ApoB were not linked to plaque progression in LMHRsExisting plaque did predict future plaque accumulation in LMHRsIndividualized approaches to cardiovascular risk assessment are crucial to serve this group better.
Episode 2612 - Vinnie Tortorich speaks with Dave Feldman about being a "citizen scientist," his documentary "Cholesterol Code," and more. https://vinnietortorich.com/2025/02/citizen-scientist-dave-feldman-episode-2612 PLEASE SUPPORT OUR SPONSORS YOU CAN WATCH ALL THE PODCAST EPISODES ON YOUTUBE - Citizen Scientist People challenge Dave and the information he gives about cholesterol because he is an engineer, not a formally trained scientist. (5:00) He has gained abundant knowledge through the studies and scientists he has worked with. (8:00) Being a citizen scientist has advantages and disadvantages; while it allows for innovative insights, it can also lead to skepticism from trained professionals regarding credibility and expertise. He has also started the Citizen Science Foundation. Dave started learning more about cholesterol after having questionable test results. (14:00) He describes signs of a bad metabolism and that issues like insulin resistance are drivers of cardiovascular disease. (19:00) Metabolic health is a more critical cardiovascular risk indicator than LDL cholesterol levels, challenging traditional medical assumptions. Lean Mass Hyper Responders, a term coined by Feldman, describes individuals on low-carb, high-fat diets who exhibit high LDL cholesterol levels but maintain good metabolic health, sparking significant interest and further research. (22:00) Cholesterol Code Movie Dave recaps his journey and discusses the making of the documentary, “Cholesterol Code.” (44:00) The film features personal narratives from individuals using ketogenic diets for various health issues, highlighting their experiences with cholesterol and metabolic health. “Cholesterol Code” incorporates scientific studies, emphasizing accurate representation of research findings and avoiding misleading claims, presenting a balanced view of ketogenic diets. The team is exploring distribution options on major streaming platforms, aiming to reach a broad audience and continue raising awareness about the importance of metabolic health. Go to and to learn more. You can find Dave posting most frequently on X @realDaveFeldman More News If you are interested in the NSNG® VIP group, register here! Don't forget to check out Serena Scott Thomas on Days Of Our Lives on the Peacock channel. “Dirty Keto” is available on Amazon! You can purchase or rent it . Make sure you watch, rate, and review it! Eat Happy Italian, Anna's next cookbook is available! You can go to You can order it from . Anna's recipes are in her cookbooks, website, and Substack–they will spice up your day! There's a new NSNG® Foods promo code you can use! The promo code ONLY works on the NSNG® Foods website, NOT on Amazon. https://nsngfoods.com/ [the_ad id="20253"] PURCHASE DIRTY KETO (2024) The documentary launched in August 2024! Order it TODAY! This is Vinnie's fourth documentary in just over five years. Visit my new Documentaries HQ to find my films everywhere: Then, please share my fact-based, health-focused documentary series with your friends and family. Additionally, the more views, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! PURCHASE BEYOND IMPOSSIBLE (2022) Visit my new Documentaries HQ to find my films everywhere: REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere:
Become a member of The Metabolic Initiative to access exclusive ad-free episodes, 100s of videos on metabolic health, and earn CMEs here.What's the best way to optimize metabolic health? In this powerhouse episode of The Metabolic Link, we bring together leading experts including Dr. Ben Bikman, Dr. Richard Johnson, Dr. Jonathan Jun, Dr. Nick Norwitz, and Dave Feldman from our Optimizing Metabolic Health Symposium filmed at Metabolic Health Summit 2024 and hosted by Dr. Dominic D'Agostino.In this discussion, you'll dive into some of the biggest questions in metabolism, including:What are the long-term effects of GLP-1 medications on fat, muscle, and metabolism?Does long-term dieting slow metabolism? And if so, can you reverse it?How do diet and fasting influence neuropathy and nerve function? Exercise and lipid profiles—what makes an athletic metabolism different?Do high-protein diets really harm the kidneys, or is it a myth?What is the role of the microbiome in weight gain, fat loss, and metabolic adaptation?And much more! With insights from top scientists and researchers, this episode is packed with takeaways for anyone looking to improve their metabolic health.Special thanks to the sponsors of this episode:Genova Connect: Get 15% off any Genova Connect test kits by using the code METABOLICLINK hereMaui Nui Venison: Gain access to a limited collection of our favorite Maui Nui products hereZocdoc: Visit this link to find and instantly book a top-rated doctorPuori: Get 20% off Puori supplements! If you choose their already discounted subscription, that's almost a third off the price! Use the code METABOLICLINK hereIn every episode of The Metabolic Link, we'll uncover the very latest research on metabolic health and therapy. If you like this episode, please share it, subscribe, follow, and leave us a comment or review on whichever platform you use to tune in!You can find us on all your major podcast players here and full episodes are also up on our Metabolic Health Summit YouTube channel!Find us on social: Instagram Facebook YouTube LinkedIn Please keep in mind: The Metabolic Link does not provide medical or health advice, but rather general information that does not serve as a substitute for a licensed healthcare professional. Never delay in seeking medical advice from an appropriately licensed medical provider for any health condition that you may have.
BARE KNUCKLE President in the Building!Tim "Red Hawk" Welch is joined BKFC President Dave Feldman. Dave tells all on the early days of BKFC, the growth of the company, Conor Mcgregor purchasing a stake in the company and fighting in the organization and more!⚡️Check out PrizePicks! Click here: https://prizepicks.onelink.me/ivHR/TIMBO and use the code "TIMBO" for a 100% Deposit Match Up to $100⚡️Check out VIIA Hemp! Use code: TIM for 15% off! https://bit.ly/viiatim♠️ Check out Spade! Use Code: TIMBOSPADE10 FOR 10% OFF!!https://www.amazon.com/stores/SPADE/page/91C86242-444D-487E-9D63-3FBB1503187F?ref_=ast_blnTimestamps0:00 Intro0:13 Welcome Dave Feldman!0:25 PrizePicks! Code TIMBO1:30 Dave's Best Skill1:46 Dave Never Sleeps 2:16 Does Dave Do Any Drugs?2:45 Dave's Intro into Promoting Fights3:48 How Dave Created BKFC4:59 The First BKFC Events Were Illegal?6:06 How Dave Get BKFC Sanctioned in a States7:15 BKFC is Safer than MMA?7:44 Are Hand Breaks More Frequent in BKFC?8:45 How the BKFC Ruleset was Created9:55 The Last BKFC Show had 17,000 Fans in Attendance10:22 Dave Gives Out a Ton of Fight Bonuses 10:45 BKFC Fighters vs MMA Fighters11:56 The Stressful Ups and Downs of Promoting Fights13:40 The ELITE BKFC Team 14:39 Dave's Scariest Moments in BKFC16:14 How Dave Sealed the Conor McGregor Deal17:51 Will McGregor Fight in BKFC?18:38 VIIA CODE TIM19:20 Who Would McGregor Fight in BKFC?21:07 BKFC's $25 million Dollar Tournament 23:06 The INSANE $25 Million Dollar Tournament Rules23:31 Who Will Fight in the Tournament (Eddie Alvarez, Mike Perry, Etc.)24:25 The Winner of the Tournament Makes $15 Million?!24:45 How BKFC Gets in Contact with DAZN, Netflix, Etc25:22 Dave's Advice for Aspiring Fight Promoters27:13 How the $25 Million Tournament is Being Funded 28:58 Dave Must Be Under a TON of Stress29:39 Fighting and Getting Screwed Over By Promoters30:07 BKFC is Growing FAST31:17 Tim's Reaction to the $25 Million Tournament 31:42 Joe Riggs is Fighting Soon?32:45 Tim's Reaction to Strickland Backlash Post UFC 31233:34 Pereira vs DDP BREAKDOWN33:59 Khamzat vs DDP BREAKDOWN35:24 Red Hawk Fighters are Going to WAR 36:00 A Big Reason to Be Thankful Boys36:54 It's Time to Become High Agency Men39:01 Grok vs Chat GPT39:43 UFC Roster Breakdown40:08 American Wrestling Doesn't Work in the UFC?42:20 Luke Rockhold's Strickland Comments42:43 Jeremey Stephens Resiging with BKFC?43:04 New Pod Studio is Coming Boys
Tyler Goodjohn known as El tornado is a bare knuckle fighter. In this quality episode we talk all things boxing and bareknuckle, from fighting on AJ and Tyson Fury undercards to Bareknuckle Fight nights in the US. Tyler also exposes promoter controversy in both sports including a heated argument with Eddie Hearn and was even sacked by Bare Knuckle's Dave Feldman.This is the eventful life of Mr Tyler GoodjohnYouTube: Dodge WoodallInstagram: @Dodge.WoodallWebsite: DodgeWoodall.comTikTok: @DodgeWoodallLinkedIn: @DodgeWoodall Hosted on Acast. See acast.com/privacy for more information.
Kurt Becker's Stroll Through Racing History presented by Keeneland - Kurt remembers Chicago turf writer, Dave Feldman.
Presented by TwinSpires A special “Best of 2024” edition of the Equine Forum. Mike Penna looks back at some of his favorite moments of the year, featuring interviews with jockey Brian Hernandez, trainer Dale Romans, Hall of Fame trainer Neil Drysdale, Hall of Fame jockey Mike Smith, and Fox Sports reporter Laffit Pincay III. Plus, Joe Kristufek discusses ways to attract new fans to thoroughbred racing in this week's TwinSpires Triple Play, Kurt Becker remembers Dave Feldman in his weekly Stroll Through Racing History presented by Keeneland, and Dale Romans & Tim Wilkin with a Breeders' Cup wrap up edition of 'I Ask, They Answer' presented by the University of Louisville Equine Industry Program in the College of Business.
Dr. Nicholas Norwitz obtained his PhD in ketogenic metabolism and neurodegenerative diseases at Oxford University and is now set to pursue his MD at Harvard Medical School. Although his research expertise is ketosis and brain aging, he has published scientific papers on topics ranging from neuroscience to heart disease to gastrointestinal health to genetics to bone health to diabetes. Dave Feldman is a senior software engineer and entrepreneur. He began working with programming and system engineering at a very young age and has always enjoyed learning new mechanistic patterns and concepts.After starting a low carb diet, Dave found his cholesterol numbers increased considerably. He then began reverse engineering the lipid system through self-experimentation and testing, finding it was very dynamic and fluid. He has now demonstrated this multiple times by moving his cholesterol up and down substantially in a matter of days. Instagram: @nicknorwitzPhD @realdavefeldman Twitter: @nicknorwitz @realDaveFeldman YouTube: / @nicknorwitzphd / @realdavefeldman Timestamps: 00:00 Trailer. 00:46 Introduction. 06:00 50% increase in LDL. 12:00 VLDL delivers, HDL picks up. 17:51 Anaerobic exercise. 25:17 Insulin resistance. 27:59 Metabolic impact and risk assessment. 33:44 Absurd narrative on keto. 39:36 Defining low carb and ketogenic diets. 41:49 Damaging low-carb image. 48:38 Satiety and keto. 51:12 Where to find Nick and Dave. See open positions at Revero: https://jobs.lever.co/Revero/ Join Carnivore Diet for a free 30 day trial: https://carnivore.diet/join/ Carnivore Shirts: https://merch.carnivore.diet Subscribe to our Newsletter: https://carnivore.diet/subscribe/ . #revero #shawnbaker #Carnivorediet #MeatHeals #HealthCreation #humanfood #AnimalBased #ZeroCarb #DietCoach #FatAdapted #Carnivore #sugarfree
Dave Feldman is the founder of the Citizen Science Foundation and is known for his research into the ketogenic diet. Dave is a software engineer by training who embraced a ketogenic diet to avoid his progression toward type 2 diabetes. he joins us on this episode of STEM-Talk to share that journey. After undertaking the high-fat/low-carbohydrate diet, Dave' LDL cholesterol spiked. Dave used his training as an engineer to start learning everything he could about cholesterol and lipids. What he learned led him to create the website Cholesterol Code, a research hub for information and emerging data on cholesterol, particularly in the context of a low-carbohydrate lifestyle. Dave's Citizen Science Foundation is designed to support projects and research that promote collaborative efforts across multiple disciplines, both in and outside formal scientific institutions. Show notes: [00:02:53] Dawn opens the interview asking Dave what he was like as a kid. [00:03:44] Dawn mentions that Dave divided his time as a child between Denver and Wichita due to his parents' divorce and asks Dave what the best part of his childhood was. [00:04:28] Ken mentions that Dave has described both his parents as graphic artists and Bohemian, “hippie spirit” types. Ken asks what he learned from them that fueled his interests and goals. [00:05:46] Ken asks about Dave's first computer, which was a Commodore 64, as well as his early experience with computers. [00:08:50] Dawn mentions that Dave's interest in computers came in a time before the internet and asks what he learned about computing in those days. [00:10:51] Dawn explains that since Dave grew up in the 1980s, there was not much in the way of computer science curriculum in schools and asks Dave how he supported his interest in programming. [00:12:33] Ken asks Dave about how self-directed learning has been a theme throughout his whole life. [00:14:35] Dawn asks Dave about his childhood hobbies, including running and competitive storytelling. [00:17:01] Ken asks how Dave's experiences in forensic debate in high school helped his career later in life. [00:18:56] Dawn mentions that Dave initially attended film school and asks if it is true that Dave's side hustle of doing contract software work overtook his original plan to graduate. [00:20:49] Dawn asks about Dave's experiences working in the game platform development business in Las Vegas, as well as what these experiences taught him. [00:22:23] Ken asks Dave about a “the piece of paper” that Dave says changed his life in 2015. [00:28:58] Ken follows up, asking Dave if he checked his LDL-P or his ApoB at the same time as his cholesterol levels. [00:30:37] Ken mentions that he knows some people that when consuming a ketogenic diet did not see a substantial increase in LDL-C, but did experience a substantial elevation of LDL-P. [00:35:03] Ken pivots to discuss a paper that Dave and others published in Current Developments in Nutrition in 2022 titled: “Elevated LDL Cholesterol with a Carbohydrate-Restricted Diet: Evidence for Lean Mass Hyper-Responder Phenotype.” Ken asks Dave to describe what it means to be a lean mass hyper-responder. [00:40:19] Ken mentions his caution against the term lean mass hyper-responder, as it is unclear what “lean mass” refers to in this case. Ken goes on to say that while the lean mass hyper-responder phenotype can be objectively measured in terms of LDL, HDL and triglyceride levels, the lean mass aspect is often measured in these studies with BMI, which is unable to measure body composition. Ken asks Dave what his thoughts are on this and if he would like the possibility of moving away from BMI and towards DEXA scans. [00:43:37] Ken mentions that Dave's original article describing the lean mass hyper-responder phenotype has received a lot of response from individuals claiming to fall into that category. While it is difficult to get a precise estimate of the popul...
Ariel Helwani around (6:04) gives an update on the status of Conor McGregor and the UFC 303 main event. Michael Chiesa around (30:31) discusses the drama surrounding UFC 303, McGregor vs. Chandler, his upcoming fight against Tony Ferguson, his previous scheduled fight against Ferguson, whether retirement is in his head, his MMA journey, the Chiesa curse, and more Arman Tsarukyan around (1:01:53) discusses Islam Makhachev's win over Dustin Poirier, why the Makhachev who showed up to UFC 302 would be an easy fight, Makhachev calling for a welterweight title shot, wanting to fight at Madison Square Garden, a timeline for the matchup, private jets, choking out alligators, and more. Savannah Marshall around (1:33:05) discusses her MMA debut against Mirela Vargas at Saturday's PFL Europe event, how the opportunity came about, why the transition has been much harder than she expected, training with Tom Aspinall, having the full Aspinall family in her corner, the chances she never boxing again, and more. Curtis Blaydes around (2:01:25) discusses his UFC 304 interim title challenge against Tom Aspinall, Ciryl Gane turning down the opportunity, why Jon Jones isn't a real heavyweight champion, why Aspinall is the most skilled heavyweight in the world, why he's going to be a vampire for a week in Manchester, and more. The Parlay Boys around (2:21:16) make their latest sections for the combat sports weekend. On the latest edition of On the Nose around (2:41:14), Ariel Helwani and crew discuss the UFC's all-in embrace of Donald Trump, how relationships with MMA managers work, the possibility of Max Holloway vs. Michael Chandler, the coverage of women in MMA compared to the recent WNBA controversies, the history of pound-for-pound, whether Islam Makhachev gets enough credit, MMA Mt. Rushmores, casting an MMA version of ‘Inside the NBA,' and more. Dave Feldman and Nobuyuki Sakakibara around (3:30:06) announce a new partnership between BKFC and RIZIN, what the partnership means, how it came together, Dana White, the possibility of Robbie Lawler joining BKFC, the status of Kyoji Horiguchi, and more. If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL/IN/MI/NJ/PA/WV/WY), 1-800-NEXT STEP (AZ), 1-800-522-4700 (CO/NH), 888-789-7777/visit http://ccpg.org/chat (CT), 1-800-BETS OFF (IA), 1-877-770-STOP (7867) (LA), 877-8-HOPENY/text HOPENY (467369) (NY), visit OPGR.org (OR), call/text TN REDLINE 1-800-889-9789 (TN), or 1-888-532-3500 (VA). 21+ (18+ NH/WY). Physically present in AZ/CO/CT/IL/IN/IA/LA/MI/NH/NJ/NY/OR/ PA/TN/VA/WV/WY only. New customers only. Min. $5 deposit required. Eligibility restrictions apply. See http://draftkings.com/sportsbook for details. Learn more about your ad choices. Visit podcastchoices.com/adchoices
Episode #311. Some people follow a ketogenic diet seeking to lose weight, feel more energised, or gain control over their eating habits. Others may turn to this diet in an effort to treat their epilepsy, bipolar disorder, or diabetes. Regardless of their reasoning for adopting this eating pattern, a key question remains: can high LDL cholesterol levels on a ketogenic diet be safe? Today I sit down with Dr William Cromwell, MD and Dave Feldman to explore this question. In this discussion, Dr William Cromwell and Dave Feldman share their professional opinions on whether high cholesterol on a keto diet is a problem. We investigate where their opinions align and where they differ, where Dave's hypotheses diverge from the norm, and what we do and don't know with the available evidence. We also explore the significance of ApoB, lifespan and healthspan considerations, research Dave is currently conducting, and much more. Specifically, we discuss: Intro (00:00) Dr. William Cromwell: Background as a Lipidologist and LDL Research (01:54) Dave Feldman's Ketogenic Diet and Elevated LDL Experience (05:34) Unpacking the Lipid Hypothesis and Cardiovascular Risk (12:30) The history and evolution of the lipid hypothesis (20:40) The role of apoB lipoproteins in atherosclerosis (23:39) Factors beyond apoB involved in atherosclerosis and mortality risk (31:59) The complexity of interpreting mortality data in the context of apoB (41:40) Macrophages and the process of atherosclerosis (44:00) Beyond ApoB: Metabolic Vulnerability, Inflammation and Mortality Risk (52:57) Transcytosis: A New Perspective on LDL Movement and Atherosclerosis (1:10:36) Exploring Low Cholesterol Impacts and Genetic Disorders (1:17:30) Macrophage function and phenotype in the context of different drivers of high apoB (1:22:30) Defining Lean Mass Hyper-responders in the Context of a Ketogenic Diet (1:31:40) Investigating PCSK9 and Its Effects on Healthspan (1:38:00) Assessing cardiovascular risk in lean mass hyper-responders (1:43:50) Statin safety, adverse effects, and patient reluctance (2:01:54) Ketogenic Diets and Elevated LDL: Balancing Individual Risks and Benefits in the Absence of Long-term Data (2:10:40) Insulin Resistance, ApoB, and Cardiovascular Risk: Navigating the Challenges in Assessment and Imaging (2:18:12) Lean Mass Hyper-responder Study: Design, Recruitment, and Eligibility Criteria (2:32:45) Closing Perspectives on Research and Dietary Options (3:04:47) Outro (3:06:42) Connect with Dr William Cromwell on Twitter/X, LinkedIn, and his website, https://www.mylipid.com/. Discover more of his work with Precision Health Reports on Twitter/X, LinkedIn, Facebook, Instagram, and at https://precisionhealthreports.com/. Connect with Dave Feldman on Twitter/X, YouTube, and Instagram, and discover more of his work at https://citizensciencefoundation.org/, https://ownyourlabs.com/, and https://cholesterolcode.com/. This episode is brought to you by: InsideTracker If you want to improve your health, you need to measure where you're currently at. InsideTracker analyses up to 48 blood biomarkers including ApoB, LDL, HDL, A1C, and more before giving you advice to optimise your health. Get a 20% discount on your first order at insidetracker.com/simon. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet's best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Sun Home Saunas Invest in your body and mind with Sun Home Saunas, pioneers in crafting premium saunas and cold plunges. Safe, effective, research-backed wellness tools to improve cardiovascular health, offer psychological benefits, and reduce muscle soreness. Head to sunhomesaunas.com/theproof for $300 off your purchase.
I am honored to reconnect with Dave Feldman today. Our last encounter was in December 2020, for Episode 128, where we delved deeply into the topic of cholesterol. Dave is an engineer by profession. He is profoundly clever and commands great respect within the low-carb and keto community due to his willingness to challenge prevailing narratives, encouraging us to explore alternative perspectives on lipid metabolism and reconsider our understanding of LDL, particularly in the context of lean mass hyper-responders like myself. In our discussion today, we dive into how LDL became so vilified, with Dave shedding light on several crucial research findings. We explain what low-mass hyper-responders are, examine biases and cognitive dissonance, touch on Dave's new LMHR study, and discuss the Miami Heart study, a longitudinal study of the roles of LDL and plaque burden. We also explore the impact of ApoB and reflect on the essence of science as a pursuit of truth, and Dave shares what lies ahead for himself and his research. I trust you will find this conversation engaging and thought-provoking. IN THIS EPISODE YOU WILL LEARN: Why LDL is considered a villain How AMRs and APB lipoproteins have influenced how we look at risk stratification What is a lean mass hyper-responder? How a low-carb, high-fat diet can improve the metabolic health of lean mass hyper-responders How Dave, an engineer turned scientist, challenges conventional wisdom in the health and wellness space Dave discusses a study on plaque progression in healthy individuals, focusing on correlating LDL levels How we are at the forefront of finding the significance of lean mass hyper-responders and LDL Dave shares the next thing he and his team will look at to substantiate his findings on lean mass hyper-responders Connect with Cynthia Thurlow Follow on Twitter Instagram LinkedIn Check out Cynthia's website Submit your questions to support@cynthiathurlow.com Connect with Dave Feldman On his website Instagram X Facebook Previous Episode Mentioned Ep. 128 – Cholesterol Obsession: Why It's the Intellectual Property of the Animal Kingdom with Dave Feldman
The current thoughts around LDL cholesterol center on the fact that there is no scenario in which high LDL numbers could occur in healthy individuals. Traditionally, the belief is high levels of LDL can lead to a greater risk of cardiovascular disease regardless of metabolic health. Today's guest is here to share his hypothesis and research on how higher cholesterol levels in metabolically fit individuals could be a physiological response rather than a pathological response that can lead to disease. Today on The Dhru Purohit Show, Dhru sits down with Dave Feldman to discuss high levels of LDL in metabolically healthy individuals. Dave shares the current research on high LDL and cardiovascular disease in individuals eating a ketogenic diet. He also shares his personal approach to focusing on metabolic health and the key markers critical to overall health. Dave discusses the process and findings of the Oreo experiment conducted by his colleague and explains why this experiment further proves their hypothesis on how LDL particles move through the body. Dave Feldman is a software and platform engineer, entrepreneur, and founder of the Citizen Science Foundation. Through a series of self-experiments and partnering with formal researchers, he has since published the "Lipid Energy Model," which may explain this phenomenon. In this episode, Dhru and Dave dive into (audio version / Apple Subscriber version):Dave's hypothesis on LDL (00:24 /00:24)Rethinking our approach to high LDL (2:17 / 2:17) The research on high LDL and cardiovascular disease (10:00 / 6:48) The Oreo experiment and what it shows about fat adaptation (17:23 / 13:45)The pushback to lean mass hyper responder (27:36 / 24:15) Soft plaque versus hard plaque and the risk of cardiovascular disease (37:50 / 35:04) Dave's personal approach in focusing on overall metabolic health (51:42 / 48:30) Fasting Insulin and Vitamin D (59:33 / 53:45) Endothelial health and cardiovascular health (1:03:28 / 57:45) The vegan's twin study and the correlation to LDL (1:21:17 / 1:15:49)Dhru's experience (1:32:17 / 1:26:36) Also mentioned in this episode:Citizen Science Foundation Oreo Cookie TreatmentNicolas Norwitz, PhD Twitter This episode is brought to you by LMNT, Momentous, and Lumebox. Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to DrinkLMNT.com/dhru today.Optimize your Omega-3 levels by choosing a quality fish oil made by and used by the best. Go to livemomentous.com and enter promo code DHRU to get 20% off any order. Lumebox is offering my community $260 off their FDA-approved portable Red Light device! That's over 50% off! Go to thelumebox.com/dhru and get your Red Light device. Hosted on Acast. See acast.com/privacy for more information.
Episode 2453 - On this Friday's show Vinnie Tortorich welcomes Dave Feldman back to discuss the cholesterol conundrum with "The Oreo Test," and more. https://vinnietortorich.com/2024/02/cholesterol-conundrum-dave-feldman-episode-2453 PLEASE SUPPORT OUR SPONSORS YOU CAN WATCH THIS EPISODE ON YOUTUBE - Cholesterol Conundrum Dave is an LMHR (lean mass hyperresponder) and explains what his “protocol” was. (2:30) He explains exactly how his protocol works. The cholesterol that you eat passes through you; however, the cholesterol that travels through your blood is produced by your liver. (7:00) Your body tries to keep a level of homeostasis. There are various opinions regarding cholesterol, but doctors are often required to prescribe statins. (10:00) Dave refers to Nick Norwitz and sample cholesterol levels. They discuss the term “settled science”. (16:00) Scientists should always be prepared to challenge their hypotheses. (19:15) Science depends on replication to confirm. You can donate to help fund the studies: is a 501(c)(3) non-profit, so your donation is tax-deductible. The conference Dave is presenting in Las Vegas in March this year is the Collaborative Science Conference at . His current studies have been entirely grass-roots funding. Nick Norwitz's Oreo Study They launch into “the Oreo study”. (30:00) Nick Norwitz compared what would happen to his cholesterol if he pitted Oreos vs Statins. What was it about the Oreos that made LDL drop? How does an LMHR control the higher cholesterol? Data was gathered by Dr. Tro Kalayjian's team using some if his LMHR patients. The studies highlight the cholesterol conundrum. Vinnie asks Dave about a second study called “the Twin Study." (48:30) The finding claimed the benefits of a vegan diet, but the standards used are questionable. Dave is working on a documentary with the team that made “Fat Fiction.” (53:00) There are a lot of key moments captured in it, as well as a lot of frustrating stories because of the misunderstandings around high LDL. Vinnie is impressed with the variety of input he's getting for the documentary. Look for Vinnie's NSNG® VIP Community and sign up for the waitlist! Go to to sign up! [the_ad id="20253"] PURCHASE BEYOND IMPOSSIBLE (2022) The documentary launched on January 11! Order it TODAY! This is Vinnie's third documentary in just over three years. Get it now on Apple TV (iTunes) and/or Amazon Video! Link to the film on Apple TV (iTunes): Then, Share this link with friends, too! It's also now available on Amazon (the USA only for now)! Visit my new Documentaries HQ to find my films everywhere: REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: Then, please share my fact-based, health-focused documentary series with your friends and family. The more views, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere: Then, please share my fact-based, health-focused documentary series with your friends and family. The more views, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter!
Episode 2435 - On this Friday's show Vinnie Tortorich welcomes back Dave Feldman to discuss Citizen Science and its LMHR study, and more. https://vinnietortorich.com/2024/01/citizen-science-with-dave-feldman-episode-2435 PLEASE SUPPORT OUR SPONSORS YOU CAN WATCH THIS EPISODE ON YOUTUBE - Making Noise Dave explains a recent double-blind study and the recent data shared with him. (5:00) He defines an LMHR (Lean Mass Hyper Responder) as high LDL, high HDL, and low triglycerides. He explains his background to folks unfamiliar with him. (7:00) Dave is an engineer and noticed a pattern or system. He shares the study with LMHR was about and some of its challenges. Awareness of LMHR is growing, so it should be studied even further. Funding such studies is difficult; however, the low-carb community has stepped up. The study analyzes how much LDL independently induces a high rate of atherosclerosis (lesions on the artery walls). (23:00) The participants are part of a year-long study that will measure plaque volume and soft plaque progression. The majority of studies done are on people who already have various diseases. (32:00) Dave would like to see a larger percentage of studies done on healthy populations to find a common baseline of biomarkers. Dave shares some information about Dr. Matthew Budoff's presentation that may be more useful to view on YouTube. To view the slides go to Vinnie's YouTube channel for this episode to view the discussion. (36:00) It discusses the quantifying of atherosclerosis with CCTA. Dave goes through the slides and explains the findings. A total plaque sore is discussed. (48:45) LDL cholesterol does not correlate with the progression of plaque. The caveat: this is preliminary data and more information needs to be collected. (56:50) Both Dave and Vinnie hope that the funding they have received for projects will help people learn and be empowered. (1:01:00) You can help fund such studies through Citizen Science at . [the_ad id="20253"] PURCHASE BEYOND IMPOSSIBLE (2022) The documentary launched on January 11! Order it TODAY! This is Vinnie's third documentary in just over three years. Get it now on Apple TV (iTunes) and/or Amazon Video! Link to the film on Apple TV (iTunes): Then, Share this link with friends, too! It's also now available on Amazon (the USA only for now)! Visit my new Documentaries HQ to find my films everywhere: REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY 2 (2021) Visit my new Documentaries HQ to find my films everywhere: Then, please share my fact-based, health-focused documentary series with your friends and family. The more views, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter! FAT: A DOCUMENTARY (2019) Visit my new Documentaries HQ to find my films everywhere: Then, please share my fact-based, health-focused documentary series with your friends and family. The more views, the better it ranks, so please watch it again with a new friend! REVIEWS: Please submit your REVIEW after you watch my films. Your positive REVIEW does matter!
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