Podcasts about Creatine

Creatine has officially entered its main character era.For years, creatine was marketed almost exclusively to bodybuilders, athletes, and gym bros. But suddenly it's showing up everywhere, from menopause experts and neurologists to longevity researchers and wellness influencers.So what's changed?In this episode, we break down what creatine actually is, what it does inside the body, and whether it deserves all the attention it's getting. We discuss muscle health, menopause, brain function, aging, independence, and the biggest myths that continue to scare people away from one of the most researched supplements available.If you've ever wondered whether creatine is right for you, this episode will help you separate the science from the marketing.In This Episode:✔ What creatine actually does✔ Why women are finally part of the conversation✔ Muscle health and longevity✔ Menopause, estrogen decline, and recovery✔ Creatine and cognitive health✔ Water retention and bloating myths✔ Kidney health misconceptions✔ How much creatine you really need✔ What type of creatine to buy(00:00:52) Welcome to the Podcast(00:06:04) Supplements should supplement, not replace, nutrition(00:07:42) Why we are talking about creatine(00:09:30) Who is creatine for?(00:16:20) Creatine is a misunderstood supplement(00:20:56) Women's longevity & independence(00:26:55) The Menopausal journey, estrogen & muscle loss(00:34:54) Creatine and brain health(00:40:55) Bloating, water retention & scale myths(00:47:54) Does creatine damage your kidneys?(00:51:18) How much creatine should you take?(00:53:41) Choosing the right creatine supplementWant to leave the TTSL Podcast a voicemail? We love your questions and adore hearing from you. https://www.speakpipe.com/TheThickThighsSaveLivesPodcast⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The CVG Nation app, for ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠iPhone⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠The CVG Nation app, for Android⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Our ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Fitness FB Group⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠.⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Thick Thighs Save Lives Workout Programs⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Constantly Varied Gear's ⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Workout Leggings⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠⁠Disclaimer: The information shared in this podcast is for educational and informational purposes only and is not intended as medical advice. The views expressed are those of the hosts and guests and should not be used as a substitute for professional medical diagnosis, treatment, or advice. Always consult your physician or qualified healthcare provider before making changes to your diet, exercise routine, medications, supplements, or healthcare plan.Statements regarding supplements and wellness products have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease.

Episode Highlights With KatieWhy the traditional biochemical model of the body is incomplete...and why the body is electric firstThe shocking amount of energy your body generates each day (about your own body weight in ATP!)Why 90–95% of chronic diseases have mitochondrial dysfunction at the rootHow your mitochondria act not just as powerhouses but as quantum batteries, antennas, and information hubsThe surprising sources of electrons that create cellular voltage...including sunlight, melanin, movement, structured water, and the earth itselfHow infrared light charges your “quantum battery,” while artificial blue light breaks it downWhy hydration with minerals is essential for building cellular charge (and why plain water can ake things worse)The nutrients mitochondria require to function: phospholipids, healthy fats, CoQ10, copper, B-vitamins, carnitine, creatine, and moreWhat redox really means and why redox balance must come before detoxHow a collapse in redox leads to the Cell Danger Response, chronic symptoms, and stalled healingThe many ways modern life drains voltage: lack of sunlight, EMFs, stress, toxins, blue light, poor sleep, dehydration, and circadian disruptionSimple daily strategies to restore voltage...starting with light, minerals, movement, grounding, and sleepHow tools like red/near-infrared light, PEMF, BioCharger, sauna, cold therapy, Juvent, and vibration plates support mitochondrial energyResources MentionedRed light therapyPEMF matBioChargerSaunasPower Plate vibration plateCold plungeJuventJustine ClassThe Body ElectricDr courtney hunt insta and websiteYour spark is light classMineral podcast seriesWater structure pitcher affiliate linkRebounder on amazon

I am honored to connect with Dr. Stacy Sims today. She is a forward-thinking international exercise physiologist and nutrition scientist on a mission to revolutionize exercise and nutrition performance- particularly for women. In our conversation, we discussed the exclusion of women from research in the modern science era and how gender differences begin in utero. We look into the importance of tracking our menstrual cycles, the differences between follicular and luteal phases, and problematic ovulatory cycles, exploring the current research on oral contraceptives, the impact of the Women's Health Initiative, and the kind of training that is essential for women in perimenopause and menopause. We also cover the physiologic changes that occur in perimenopause and menopause, and Dr. Sims shares her thoughts on weight loss resistance, SECO, undereating, the importance of protein, and essential supplements for middle-aged women. I know you will love this invaluable conversation with Dr. Stacy Sims. IN THIS EPISODE YOU WILL LEARN: Why are women still excluded from many studies? How the physiological differences between men and women begin in utero and continue through adulthood How stress during pregnancy affects the developing fetus How the muscle morphology of women differs from that of men  Why girls need to learn new ways to move and build strength during puberty How tracking menstrual cycle phases helps women optimize their training The potential long-term effects of using oral contraceptives Why a diverse diet is essential for supporting gut health Common misconceptions surrounding hormone therapy Why Dr. Sims recommends creatine for women in perimenopause and menopause Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website. Submit your questions to support@cynthiathurlow.com  Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.  Purchase Cynthia's book, The Menopause Gut. Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Dr. Stacy Sims  On her⁠ website⁠ Instagram⁠ ⁠Facebook⁠ ⁠TikTok

Creatine is one of the most studied supplements in the world, but most people misunderstand how it works, or when it's beneficial. Here's what the research says about strength, water retention, brain health, and whether you even need it.   Join my NEW 90-day Carnivore Challenge group on Mighty Networks below! https://dr-chaffee-s-90-day-carnivore-challenge.mn.co/landing/ If you liked this and want to learn more go to my new website www.DrAnthonyChaffee.com

Kolie Moore of Empirical Cycling returns to That Triathlon Show! In today's episode Kolie brings lists of his top underrated and overrated factors for cycling performance to the table, and we discuss these. Kolie also tests Mikael on logical reasoning, and has him guess whether each factor is overrated or underrated on Kolie's list. HIGHLIGHTS AND KEY TOPICS:  Kolie's top underrated and overrated factors for cycling performance Without specifying which categories each of these belong in, some of the things we discuss include creatine, Zone 2 training, training plans, race specificity, and many more!  What factors did Kolie overrate or underrate earlier in his coaching career? Listener submitted overrated/underrated suggestions, including heat training, lactate guided training, genetics and more SHOWNOTES, LINKS, RESOURCES AND RELATED EPISODES:  The shownotes for today's episode can be found here.  The full podcast episode archives (including category filters) can be found here.  Kolie's website, podcast (Empirical Cycling Podcast), Instagram The Wason Test (here you can try your own logic!)  Coaching Thoughts: 15 Underrated Factors for Triathlon Performance | EP#440 - Mikael's own list of underrated performance factors (for triathlon) Coaching Thoughts: 11 Overrated Factors for Triathlon Performance | EP#439 - Mikael's own list of overrated performance factors (for triathlon) Training Talk with Kolie Moore | EP#271 - Kolie's first appearance on That Triathlon Show Training, coaching and podcasting with Mikael Eriksson and Kolie Moore | EP#359 - This episode with Kolie interviewing Mikael originally aired on Empirical Cycling and was later republished on That Triathlon Show Watts Doc #61: Quantifying Diminishing Returns Watts Doc #58: Creatine's Actual Effects On Cycling Performance Watts Doc #50: Hypoxia And Muscular Adaptation Watts Doc #40: Endurance Adaptation Is Not Substrate Oxidation Much Ado About Zone 2: A Narrative Review Assessing the Efficacy of Zone 2 Training for Improving Mitochondrial Capacity and Cardiorespiratory Fitness in the General Population - Storoschuk et al. 2025 Long-Term Time-Course of Strength Adaptation to Minimal Dose Resistance Training Through Retrospective Longitudinal Growth Modeling - Steele et al. 2022 Limited reproducibility of individual physiological adaptations to repeated endurance exercise training - Odden et al. 2026 SPONSORS: Precision Fuel & Hydration produce our favourite gels, sports drinks, and electrolyte and carbohydrate products here at That Triathlon Show and Scientific Triathlon. Use the free Fuel & Hydration Planner to get a personalised plan for your carbohydrate, sodium and fluid intake in your next event, and get 15% off your first 2026 order by using the code TTS2026 at checkout. Rouvy is hands down the most complete indoor cycling platform for triathletes. Among their thousands of beautiful bike courses from all around the world, all filmed in stunning quality, they have over 75 IRONMAN and IRONMAN 70.3 race courses plus 20+ Challenge Family courses, so you can pre-ride your race from home. Real gradients, real visuals, and real feel! Head to rouvy.com and use the code TTS to get your first month free on top of a 7-day free trial. Effortless Swimming produce the best swim goggles for triathletes and open water swimmers. Their NanoClear anti-fog lenses give you clear, fog-free vision that lasts and doesn't wear off. Don't let foggy or leaky goggles ruin another swim. Go to shop.effortlessswimming.com and use the code TTS15 to get 15% off your goggles, and get a free two-month Effortless Swimming course membership. ZenAI is the next frontier of podcasting. It lets you turn your ideas into a podcast without any knowledge of audio editing, video, or production. You do the talking, and the AI handles the production, editing, clipping, and the rest, and you can direct your AI producer in plain English. You can even record from your phone, so no expensive studio gear is needed to sound great. ZenAI is a new product from Zencastr, a platform I've been a paying customer of for over nine years here at That Triathlon Show. ZenAI is currently in invite-only beta. Join the waitlist today here.LEARN MORE ABOUT SCIENTIFIC TRIATHLON: The Scientific Triathlon website is the home of That Triathlon Show and everything else that we doContact us through our contact form or email me directly (note - email/contact form messages get responded to much more quickly than Instagram DMs)Subscribe to our NewsletterFollow us on InstagramLearn more about our coaching, training plans, and training camps. We have something to offer for everybody from beginners to professionals.HOW CAN I SUPPORT THAT TRIATHLON SHOW (FOR FREE)? I really appreciate you reading this and considering helping the show! If you love the show and want to support it to help ensure it sticks around, there are a few very simple things you can do, at no cost other than a minute of your time. 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What if aging isn't simply your body “wearing out”… but your body losing the ability to repair itself? In this episode, Dr. Andrew Salzman joins Dr. Josh Axe to explain why chronic inflammation, leaky gut, and depleted NAD may quietly drain the very energy your cells need to heal, think, move, and survive. Uncover what's really going on in your body with advanced biomarker testing for hormones, thyroid, and metabolism— plus a 1-hour consultation with a Senior Health Advisor! →  http://mybloodwork.com Thank you to our sponsors! Sunlighten Sauna: https://get.sunlighten.com/axepodcast Manukora Manuka Honey: https://manukora.com/axe Caraway Home: carawayhome.com/drjoshaxe (Use code DRJOSHAXE) for an exclusive discount Watch The Dr. Josh Axe Show every Monday & Thursday on YouTube: https://www.youtube.com/@drjoshaxe?sub_confirmation=1

When was the last time you heard someone say creatine was for women? Probably not often enough. In this episode of The Art of Living Well Podcast®, Marnie and Stephanie break down one of the most researched supplements available and make the case for why midlife women should be paying attention. Creatine has long been associated with bodybuilders and gym culture, but the science tells a far more interesting story, especially for women navigating perimenopause, menopause, and the hormonal shifts that come with them. This conversation covers the basics of how creatine works, why women naturally have lower stores than men, and what the emerging research says about its benefits for muscle, recovery, energy, and brain health. Marnie and Stephanie also share how they each take it daily, what brands they trust, and how to work through the bloating concern that keeps many women from sticking with it. Supplements are never the whole picture. But this one may be worth a closer look. Key Takeaways What creatine is and how it supports cellular energy production Why women have lower creatine stores than men How declining estrogen affects muscle mass and recovery The strength and lean muscle benefits of creatine in perimenopause and postmenopause Why brain fog and cognitive decline make creatine worth considering The truth about bloating and water retention The form, dose, and timing that Marnie and Stephanie each use What to look for on a label and brands they recommend Who should consult a doctor before starting Episode Breakdown with Timestamps 00:00 Why creatine matters for women 01:30 What creatine is and how ATP works 03:30 Why women have lower creatine stores 05:00 Strength, muscle mass, and recovery 07:00 Addressing the bloating concern 08:30 Perimenopause and postmenopause research 10:00 Brain health and cognitive function 11:30 Benefits across all life stages 12:00 Myths and contraindications 13:30 Creatine monohydrate: dosing and timing 15:00 Brands and what to look for 18:00 Final takeaways Resources and Links Kion Creatine: Code: ARTOFLIVINGWELL  Brick House Nutrition Creatone Code: livingwell Equi.Life Cell Force Website: https://www.theartoflivingwell.us  Sponsors This episode is brought to you by Good Health Saunas, offering commercial grade infrared saunas designed to support detoxification, muscle recovery, relaxation, and better sleep. Visit https://goodhealthsaunas.com or stop by their Mall of America, Appleton, or Waukesha locations. Be sure to mention The Art of Living Well Podcast® for exclusive pricing. Summer is the perfect time to press reset. Our 7-day Vitality Reboot gives you a clear, guided path to reducing inflammation and reclaiming your energy, with Marnie and Stephanie in your corner the whole way. You do the work, we provide the roadmap and the support. Join us at https://p.bttr.to/39XDmpQ Join Us This Summer — Mahjong Night! If you are local to the Twin Cities, come spend a summer evening with us. We are hosting a fun night of mahjong, connection, and community on Wednesday, July 22nd from 6:30 to 8:30 PM. Expect good company, giveaways, and plenty of laughs around the table. Tickets are $20 to play. Location will be in Edina or Minnetonka depending on the weather, and the address will be shared upon registration. Please note this event is for experienced players only and space is limited. Grab your spot before it sells out at https://l.bttr.to/t9qKg Follow and Connect Instagram: https://www.instagram.com/theartofliving_well Facebook: https://www.facebook.com/theartoflivingwellpodcast/ LinkedIn: https://www.linkedin.com/company/the-art-of-living-well-podcast/?viewAsMember=true Connect with Your Hosts Marnie Dachis Marmet: https://www.instagram.com/zenfullifecoaching Stephanie May Potter: https://www.instagram.com/stephaniemaypotter/  

In this episode of the Health, Wellth & Wisdom Podcast, host and head coach, Nicole Hagen answers four listener-submitted questions covering some of the most talked-about topics in nutrition and wellness right now: creatine, the viral "bean diet," GLP-1 medications and mood, and how to navigate the emotional ups and downs of measuring progress.Throughout this episode, you'll learn:Whether creatine is only beneficial for heavy lifters or if women can benefit from taking it tooThe research behind creatine supplementation for muscle health, strength, and agingWhy the viral "bean diet" may be helping some people lose weight The role fiber plays in satiety, blood sugar regulation, and sustainable weight lossWhether GLP-1 medications can affect mood and why some people report feeling emotionally different while taking themWhy scale and measurement fluctuations can feel emotionally charged and how to develop a healthier relationship with progress Practical ways to separate your worth and effort from the number you see on the scaleIf you've ever wondered whether you need the latest supplement, questioned a viral nutrition trend, or felt discouraged when your progress didn't look the way you expected, this episode will leave you feeling informed, reassured, and better equipped to navigate your weight loss journey with more nuance and self-compassion.Apply for 1:1 Nutrition Coaching:https://nutritioncoachingwithnicole.com/1-on-1-coachingCheck your HSA/FSA Eligibility:  https://app.truemed.com/qualify/tm_qual_q0c29x5n9v

He carried two copies of ApoE4, the highest genetic risk factor for Alzheimer's disease, went through medical school knowing exactly what his LDL of 700 meant, decided the experts were wrong, and then published the case report to prove it. In this episode, Louisa sits down with Dr. Nick Norwitz, PhD researcher and metabolic scientist, for one of the most scientifically dense conversations on brain health, cholesterol biology, and Alzheimer's prevention ever recorded on this show. They cover why the phospholipid form of DHA reaches the brain more effectively than standard fish oil, how ApoE4 carriers burn through omega-3s differently and what to do about it, the lithium orotate data that sold out supplement shelves worldwide, and why GSK-3 beta, the enzyme that phosphorylates tau, may be the most under appreciated target in Alzheimer's research today. Then Dr. Nick Norwitz lays out the case that challenges the "LDL is always the enemy" consensus: why metabolically healthy individuals may not benefit from aggressive lipid-lowering therapy, what his viral coronary CT angiogram showed after seven years of 700+ cholesterol, why the EZPAVE trial headlines don't hold up under scrutiny, and what GLP-1s are doing inside the brain completely independent of weight loss. You'll also hear about the sardine diet experiment, the omega-3 thermogenesis connection, ketones as misfolded protein clearance agents, creatine for depression, retatrutide and PCSK9, BPC-157 risks, and what Dr. Nick Norwitz believes is coming in Alzheimer's gene therapy within the next decade. *Reduce your risk of Alzheimer's with my science-backed protocol for women 30+:*https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ *TOPICS DISCUSSED*(00:00:00) Intro: The ApoE4 Paradox and the Case Report That Broke the Internet (00:00:57) Why Standard Omega-3 Supplements Fail and What to Take Instead (00:05:13) DHA and the Phospholipid Carrier: How It Crosses the Blood-Brain Barrier (00:10:19) ApoE4 Explained: Risk, Genetics, and Why Nick Is Optimistic (00:17:38) Why ApoE4 Carriers Burn Through DHA Faster and Need More (00:20:31) Women, Omega-3s, Menopause, and Brain Insulin Resistance (00:21:41) Statins, Sex Differences, and the DHA-Blood Sugar Connection (00:26:01) Statins and Dementia: What the Data Actually Say (00:32:24) Tau, GSK-3 Beta, Lithium Orotate, and Targeting Alzheimer's Pathology (00:42:19) The Glymphatic System, 40Hz Devices, and Sleep as Brain Clearance (00:45:21) Gene Editing, Prime Editing, and the Future of ApoE4 Therapy (00:49:33) Nick's Case Report: 700 LDL, Zero Plaque, and Seven Years of Data (00:55:10) The EZPAVE Trial: Why the Headlines Don't Hold Up (01:00:33) KetoneIQ: Ketones for Brain Energy and Focus (01:01:29) Cheers Health: Supporting Liver Function and Cognitive Recovery (01:03:54) If Not LDL, What Causes Heart Disease in Metabolically Healthy People? (01:12:05) The Oreo Experiment and the Sardine Diet: Self-Experiments in Metabolism (01:19:10) Ketones, Women's Brains, and Clearing Misfolded Proteins (01:21:08) The Full Brain Health Protocol: Omega-3s, Creatine, NAD, Lithium, and More (01:24:01) GLP-1s for the Brain: Independent of Weight, Targeting Amyloid and Tau (01:25:28) Peptides: BPC-157 Risks, Retatrutide, MOTS-c, and What's Worth Watching (01:29:02) Why Nick Is Controversial And Why He Doesn't Mind _______ *Thank you to our sponsors*Fenix Health Science: fenixhealthscience.com Use code NEUROEXPPulsetto: https://pulsetto.tech/pages/NEURO or use Code NEURO for some off your orderFunction Health: https://www.functionhealth.com/louisanicolaBASED Bodyworks: https://basedbodyworks.com/ and use code NEURO for 20% offKetoneIQ: https://ketone.com/NEURO for 30% OFFCheers Health: https://CheersHealth.com/NEURO or use code NEURO for 20% off _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention.If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0Instagram: https://www.instagram.com/louisanicola_/Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

He carried two copies of ApoE4, the highest genetic risk factor for Alzheimer's disease, went through medical school knowing exactly what his LDL of 700 meant, decided the experts were wrong, and then published the case report to prove it. In this episode, Louisa sits down with Dr. Nick Norwitz, PhD researcher and metabolic scientist, for one of the most scientifically dense conversations on brain health, cholesterol biology, and Alzheimer's prevention ever recorded on this show. They cover why the phospholipid form of DHA reaches the brain more effectively than standard fish oil, how ApoE4 carriers burn through omega-3s differently and what to do about it, the lithium orotate data that sold out supplement shelves worldwide, and why GSK-3 beta, the enzyme that phosphorylates tau, may be the most under appreciated target in Alzheimer's research today. Then Nick lays out the case that challenges the "LDL is always the enemy" consensus: why metabolically healthy individuals may not benefit from aggressive lipid-lowering therapy, what his viral coronary CT angiogram showed after seven years of 700+ cholesterol, why the EZPAVE trial headlines don't hold up under scrutiny, and what GLP-1s are doing inside the brain completely independent of weight loss. You'll also hear about the sardine diet experiment, the omega-3 thermogenesis connection, ketones as misfolded protein clearance agents, creatine for depression, retatrutide and PCSK9, BPC-157 risks, and what Nick believes is coming in Alzheimer's gene therapy within the next decade. Reduce your risk of Alzheimer's with my science-backed protocol for women 30+:https://go.neuroathletics.com.au/youtube-sales-page Subscribe to The Neuro Experience for evidence-based conversations at the intersection of brain science, longevity, and performance. _____ TOPICS DISCUSSED 00:00 Intro: The ApoE4 Paradox and the Case Report That Broke the Internet 00:57 Why Standard Omega-3 Supplements Fail and What to Take Instead 05:13 DHA and the Phospholipid Carrier: How It Crosses the Blood-Brain Barrier 10:19 ApoE4 Explained: Risk, Genetics, and Why Nick Is Optimistic 17:38 Why ApoE4 Carriers Burn Through DHA Faster and Need More 20:31 Women, Omega-3s, Menopause, and Brain Insulin Resistance 21:41 Statins, Sex Differences, and the DHA-Blood Sugar Connection 26:01 Statins and Dementia: What the Data Actually Say 32:24 Tau, GSK-3 Beta, Lithium Orotate, and Targeting Alzheimer's Pathology 42:19 The Glymphatic System, 40Hz Devices, and Sleep as Brain Clearance 45:21 Gene Editing, Prime Editing, and the Future of ApoE4 Therapy 49:33 Nick's Case Report: 700 LDL, Zero Plaque, and Seven Years of Data 55:10 The EZPAVE Trial: Why the Headlines Don't Hold Up 01:00:33 KetoneIQ: Ketones for Brain Energy and Focus 01:01:29 Cheers Health: Supporting Liver Function and Cognitive Recovery 01:03:54 If Not LDL, What Causes Heart Disease in Metabolically Healthy People? 01:12:05 The Oreo Experiment and the Sardine Diet: Self-Experiments in Metabolism 01:19:10 Ketones, Women's Brains, and Clearing Misfolded Proteins 01:21:08 The Full Brain Health Protocol: Omega-3s, Creatine, NAD, Lithium, and More 01:24:01 GLP-1s for the Brain: Independent of Weight, Targeting Amyloid and Tau 01:25:28 Peptides: BPC-157 Risks, Retatrutide, MOTS-c, and What's Worth Watching 01:29:02 Why Nick Is Controversial And Why He Doesn't Mind _______ Thank you to our sponsors Fenix Health Science: fenixhealthscience.com Use code NEUROEXP Pulsetto: https://pulsetto.tech/pages/NEURO or use Code NEURO for some off your order Function Health: https://www.functionhealth.com/louisanicola BASED Bodyworks: https://basedbodyworks.com/ and use code NEURO for 20% off KetoneIQ: https://ketone.com/NEURO for 30% OFF Cheers Health: https://CheersHealth.com/NEURO or use code NEURO for 20% off _______ I'm Louisa Nicola - clinical neurophysiologist - Alzheimer's prevention specialist - founder of Neuro Athletics. My mission is to translate cutting-edge neuroscience into actionable strategies for cognitive longevity, peak performance, and brain disease prevention. If you're committed to optimizing your brain- reducing Alzheimer's risk - and staying mentally sharp for life, you're in the right place. Stay sharp. Stay informed. Join thousands who subscribe to the Neuro Athletics Newsletter → https://bit.ly/3ewI5P0 Instagram: https://www.instagram.com/louisanicola_/ Twitter : https://twitter.com/louisanicola_ Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, I'm joined by obstetrician/gynecologist Dr. Hannah Ryles to talk about exercise, fertility, pregnancy, and postpartum recovery.We cover how the right kind of movement can support fertility, hormonal balance, and metabolic health, as well as when exercise can become too much stress on the body. We also talk about what types of workouts are safe while trying to conceive, how to train during each trimester, and what advice around pregnancy fitness is outdated or overly fear-based.We also dive into postpartum fitness beyond “bouncing back.” We talk about the six-week clearance, pelvic floor and core recovery, returning to strength training, and how postpartum movement can support long-term reproductive health.This episode is full of practical information for women who want to feel strong, supported, and educated before pregnancy, during pregnancy, and after birth.In this episode, we cover:How exercise can support fertility and reproductive healthWhen exercise may become too much stress on the bodyWhether you need to modify workouts during the two-week waitHow workouts may change in the first, second, and third trimesterPregnancy fitness myths that need to goWhat to know about the six-week postpartum clearanceWhy postpartum fitness is about more than weight lossHow to rebuild strength safely after birthWhat women need to understand about long-term fitness**Disclaimer: The information shared in this podcast is NOT meant to be taken as individual or medical advice. These conversations are for educational purposes only. Please seek the advice of your physician or healthcare provider regarding any medical condition or treatment.Links/Resources:Learn about the Expect App for Pregnancy Optimized FitnessJoin FIT CLUB, my monthly membership with workouts you can do at home or the gymSHOP UFYF merchandiseGrab your FREE Body Recomp Meal Prep and get the UFYF NewsletterSHOP Kion - my favorite Protein, EAA's and Creatine!Listen to the Girls with Opinions Podcast with Kristy & ErinConnect with me on Instagram @kristycastillofit and @unfuckyourfitnesspodcastJoin my FREE Facebook group, Unf*ck Your FitnessClick HERE for my favorite fitness & life thingsSend me a text with episode ideas or just to say hi! Support the show

Show notes: (0:00) Intro (0:33) Meet Dr. Nicholas Fabiano and his work in lifestyle psychiatry (4:41) Exercise, depression, prevention, and treatment (9:50) How to "prescribe" exercise using the FITT principle (15:38) Nutrition, ultra-processed foods, and mental health (17:46) Microplastics, processed foods, and exposure risks (23:58) Creatine for depression, cognition, and brain energy (28:21) Creatine, sleep loss, and cognitive performance (35:42) Sleep hygiene tips that support better rest (38:56) How CBT helps change thoughts, behaviors, and mood (43:18) CBT vs. longer-term talk therapy (45:53) Where to follow Dr. Nicholas Fabiano (46:35) Outro   Who is Dr. Nicholas Fabiano?   Dr. Nicholas Fabiano is a psychiatry resident and researcher at the University of Ottawa Department of Psychiatry. His work focuses on the connection between physical and mental health, with special interest in lifestyle psychiatry, exercise, nutrition, sleep, and supplements like creatine. He studies how these tools may support the treatment and prevention of mental health conditions, especially depression. Dr. Fabiano brings both research knowledge and a practical, patient-centered view to mental health care, helping people understand that small daily habits can play a meaningful role in how they feel, think, and function. Connect with Dr. Nicholas:   Website: https://www.nicholasfabiano.ca/ LinkedIn: https://www.linkedin.com/in/ntfabiano/ X: https://x.com/NTFabiano IG: https://www.instagram.com/ntfabiano/ Links and Resources: Peak Performance Life  Peak Performance on Facebook Peak Performance on Instagram

MOTS-c is encoded by mitochondrial DNA, which makes it quite unique compared to most peptides, which are usually encoded by nuclear DNA. This peptide helps our bodies adapt to stress, regulate energy production, and maintain metabolic balance—especially when it comes to burning fat and improving overall endurance. Read the Full Episode Transcript: https://pepties.com/mitochondrial-support-from-mots-c/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ Buy Peptides online at BioLongevity Labs: Use our link and enter COUPON CODE: PEPTIDEPODCAST  at checkout to receive 15% off your total order:  https://go.biolongevitylabs.com/SH5C Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less.  https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1)  Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners!  ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 NAD+ Push Patch: https://www.pushpatch.com/

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You've probably been hearing a lot about creatine lately. In this episode I'm discussing how the current research is relevant to vegan women in perimenopause and menopause: what creatine does for your muscles, your brain, and your bones, whether it causes weight gain, the risks, and why vegan women are in a good position to benefit. 1:34 History of creatine 2:55 How creatine works 4:08 Benefits: muscle mass and strength 5:10 Benefits: bone density 5:47 Benefits: brain and mood 6:48 How creatine fits with a vegan lifestyle 9:47 Does creatine cause weight gain? 11:24 Creatine and kidneys 12:21 Stomach discomfort 12:40 How to take creatine 13:07 Loading 13:37 Timing 14:15 Conclusion Links mentioned: Free 3-Day Vegan Menopause Meal Plan: https://blissfulmenopause.kit.com/d75525d1c8 Book a Free Discovery Call: https://calendly.com/anna-blissfulmenopause/30min Cozy Earth bamboo sheets (use code BLISSFUL for up to 20% off): https://cozyearth.com Also check out the Vegan Menopause Blog: https://www.blissfulmenopause.com/blog This episode is not medical advice. Always consult your healthcare provider before starting any new supplement, especially if you have kidney concerns or are on medication.

A Lyme disease diagnosis can feel overwhelming, but according to Dr. Barrett Deubert, the real question isn't just how to treat Lyme; it's why the immune system is struggling to keep it under control in the first place. In this episode of The Real Health Podcast, Dr. Barrett breaks down a functional approach to chronic Lyme that focuses on restoring immune resilience, reducing inflammation, improving gut health, and supporting the body's natural healing processes.You'll learn practical strategies to optimize vitamin D, balance omega-3s, improve sleep quality, regulate the nervous system, repair the gut, and support mitochondrial energy production. Dr. Barrett also explores the role of toxic burden, including mold, heavy metals, environmental toxins, and chronic infections, and explains why addressing the whole person - not just the pathogen - is key to long-term recovery.Whether you're dealing with Lyme disease, chronic mold exposure, post-viral symptoms, or simply looking to strengthen your immune system, this episode is packed with actionable insights to help you regain your health and vitality.Topics Covered:- Why immune regulation matters more than simply "killing Lyme"- The connection between toxic burden and chronic illness- Optimizing vitamin D and omega-3 levels- Gut healing: Remove, Repair, Reinoculate, Rebuild- Sleep and nervous system support for immune health- Creatine, glutathione, magnesium, and other key nutrients- Reducing neurological inflammation naturally- Practical lifestyle habits that support recovery. . . Watch the episode on YouTube here! Click here to view the episode transcript! Podcast Team Dr. Barrett Deubert - Host Grant Crenshaw - Editor DISCLAIMERThis content is strictly the opinion of Dr. Barrett Deubert and is for informational and educational purposes only. It is not intended to provide medical advice or to replace medical advice or treatment from a physician. All viewers of this content are advised to consult their doctors or qualified health professionals regarding health questions and concerns. Neither Dr. Deubert nor the Real Health Co. takes responsibility for possible health consequences of any person or persons reading or following the information in this educational content. All audience members, especially those taking prescription or over-the-counter medications, should consult their physicians before beginning any nutrition, supplement, or lifestyle program.

Episode Overview:Creatine isn't just for athletes — it may be one of the most researched and beneficial supplements for women, especially as we enter our 40s and beyond. In this episode, we're breaking down what creatine is, why it matters for muscle, metabolism, brain health, and healthy aging, and how to use it safely and effectively. Stacy shares the latest research and practical tips so you can decide if creatine is a tool that fits into your wellness routine.After listening, you'll learn:Why creatine may be especially important for women over 35 — including how it supports muscle strength, power, bone health, and aging well.The surprising connection between creatine and brain health — including its potential role in energy, mental fatigue, brain fog, and cognitive performance.How to actually use creatine — the best type to choose, how much to take, when to take it, and common myths about water weight and safety.Follow us on INSTAGRAM @dailydietitianrd

This episode explores how to use GLP-1 medications like semaglutide/Ozempic and tirzepatide/Mounjaro safely and effectively. Dr. Mike Hart and Dr. Christle Guevarra Do discuss once-weekly dosing, individualized titration, optimal dose selection, food noise, appetite suppression, and the risks of dosing mistakes with vials or gray-market peptides. They also cover why resistance training, protein, fiber, and realistic nutrition habits are essential for preserving muscle and maintaining results. The conversation expands into GLP-1 benefits beyond weight loss, including cardiovascular protection, inflammation, autoimmune flares, addiction-related behaviors, alcohol cravings, libido, menstrual cycles, PCOS, sleep apnea, and what to expect when stopping the medication. Dr. Christle Guevarra Do is a physician focused on obesity medicine, GLP-1 education, weight management, and sustainable lifestyle change. Drawing from both her clinical experience and her own long-term use of GLP-1 medication, she helps patients understand how these medications fit into the bigger picture of long-term health. Her approach emphasizes individualized care, strength training, nutrition, behavior change, and realistic maintenance strategies rather than quick fixes. In this episode, she shares practical guidance for using GLP-1s responsibly while protecting muscle, managing hunger, and building habits that support lasting results. Dr. Christle Guevarra Website https://www.drchristle.com/ Dr. Christle's Free GLP-1 Guide https://www.drchristle.com/glp1-guide Dr. Christle Instagram https://www.instagram.com/dr.christle/ Ozempic — semaglutide https://www.ozempic.com/ Wegovy — semaglutide for weight management https://www.wegovy.com/ Mounjaro — tirzepatide https://mounjaro.lilly.com/ Zepbound — tirzepatide for weight management / sleep apnea https://zepbound.lilly.com/ FDA: Concerns With Unapproved GLP-1 Drugs https://www.fda.gov/drugs/drug-alerts-and-statements/fdas-concerns-unapproved-glp-1-drugs-used-weight-loss Retatrutide Clinical Trial Info https://clinicaltrials.gov/study/NCT05882045 Vyvanse — lisdexamfetamine https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=704e4378-ca83-445c-8b45-3cfa51c1ecad Creatine — NIH Supplement Info https://ods.od.nih.gov/factsheets/ExerciseAndAthleticPerformance-HealthProfessional/ Psyllium Husk / Fiber — MedlinePlus https://medlineplus.gov/druginfo/meds/a601104.html Berberine — NCCIH https://www.nccih.nih.gov/health/berberine-and-weight-loss-what-you-need-to-know Tesamorelin — MedlinePlus https://medlineplus.gov/druginfo/meds/a611035.html CJC-1295 — PubMed Research https://pubmed.ncbi.nlm.nih.gov/16352683/ Ipamorelin — PubMed Research https://pubmed.ncbi.nlm.nih.gov/9849822/ FDA: Peptides / Compounding Safety Concerns https://www.fda.gov/drugs/human-drug-compounding/certain-bulk-drug-substances-use-compounding-may-present-significant-safety-risks Oura Ring https://ouraring.com/ White Claw https://www.whiteclaw.com/   Show Notes 00:00 Welcome to the Hart2Heart Podcast 00:45 Weekly Dosing Debate 03:41 Starting Dose Basics 06:28 Pens vs Vials Safety 08:37 Finding Your Sweet Spot 11:01 Nighttime Binge Window 13:32 Lifestyle Work Still Matters 14:30 Benefits Beyond Weight 17:27 Libido and Low Calories 22:26 Alcohol Hits Different 24:59 Cancer Claims Reality Check 26:59 Strength Training Priority 29:06 Supplements and Creatine 29:38 Creatine Protein Fiber Basics 31:50 Berberine Pros and Cons 32:37 Peptides Sleep and Muscle 35:28 Too Lean for GLP-1 38:52 Cycles PCOS and Fertility 40:45 Food Noise vs Appetite 44:42 Staying On or Stopping 49:19 Heart Rate and HRV Concerns 51:38 Ozempic vs Mounjaro Choices 54:45 Sleep Apnea and Wrap Up The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this podcast is for you.We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being. Connect with Dr. Mike Hart Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart

GLP-1 agonists, like semaglutide (brand names Ozempic and Wegovy), are peptides that mimic this natural hormone. They're typically used for managing type 2 diabetes and, more recently, for weight loss. These peptides work by enhancing insulin secretion when glucose levels are elevated, slowing down gastric emptying, and reducing appetite. They also help lower blood pressure and stabilize blood sugar and cholesterol levels. Most recently they've been approved for improving cardiovascular health.  Read the Full Episode Transcript: https://pepties.com/glp-1-microdosing/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ Buy Peptides online at BioLongevity Labs: Use our link and enter COUPON CODE: PEPTIDEPODCAST  at checkout to receive 15% off your total order:  https://go.biolongevitylabs.com/SH5C Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less.  https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1)  Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners!  ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 NAD+ Push Patch: https://www.pushpatch.com/

In this Q&A episode, I'm answering some of the fitness questions you have sent in recently, and we are covering a lot of the things that tend to make women overthink their progress.We talk about protein and whether it's possible to eat too much, how to find a fat loss calorie goal that actually works for you, and what to do if tracking macros brings out your perfectionist side. I also break down whether you need special shoes for lifting, if compound lifts are enough to build muscle, and how I became more comfortable lifting heavy weights over time.We also get into deload weeks…what they are, when to use them, and why backing off can actually help you keep making progress. And of course, we talk about cravings, willpower, mindset, and why white-knuckling your way through fitness is not the goal.This episode is practical, honest, and full of reminders that fitness does not have to be so all-or-nothing. You do not need to be perfect with your macros, scared of eating more protein, or intimidated by the gym. You need a plan, realistic expectations, and the confidence to keep showing up.Episode Recap:Protein goals and whether you can eat too muchPerfectionism with macrosFinding your fat loss caloriesShoes for liftingCompound lifts vs. isolation movementsDeload weeksBuilding confidence with heavy weightsCravings, willpower, and mindsetLinks/Resources:SHOP UFYF merchandiseGrab your FREE Body Recomp Meal Prep and get the UFYF NewsletterSHOP Kion - my favorite Protein, EAA's and Creatine!Listen to the Girls with Opinions PodcastJoin FIT CLUB, my monthly membership with workouts you can do at home or the gymConnect with me on Instagram @kristycastillofit and @unfuckyourfitnesspodcastJoin my FREE Facebook group, Unf*ck Your FitnessClick HERE for my favorite fitness & life things!Send me a text with episode ideas or just to say hi! Support the show

In this episode, Leslie Fuller, ND focused on the often-overlooked musculoskeletal symptoms experienced by women during perimenopause and menopause. She discusses strategies for effective management, including nutrition, resistance training, hormone assessment, and addressing both structural and functional health. This episode offers healthcare professionals and patients evidence-based approaches to support musculoskeletal health through the menopausall transition.Enroll now in: Under-Recognized, Under-Treated, and Misrepresented Realities of the Perimenopause and Menopause Transition, with Leslie Fuller, ND and Jillian Moehle, ND at https://pages.kharrazianinstitute.com/fuller-moehle-perimenopause00:00 Menopause-related musculoskeletal issues06:32 Assessing musculoskeletal conditions10:25 Identifying osteoporosis risk factors13:48 Comprehensive management for inflammation repair15:07 Discussing menopause and bone health18:48 Future FDA approval and nutrition strategies24:30 Effects of Isoflavones and Lignans25:40 Calcium and vitamin D benefits31:14 Creatine and CoQ10 for muscle health33:42 Importance of aerobic and resistance training38:13 Combating sarcopenia through referrals39:17 Screening for menopausal musculoskeletal syndromeSupport this show http://supporter.acast.com/solving-the-puzzle-with-dr-datis-kharrazian. Hosted on Acast. See acast.com/privacy for more information.

Click to Text Thoughts on Today's EpisodeWe are living in a supplement era — and it's overwhelming. Between Instagram reels, podcast ads, and influencer recommendations, it can feel like you need an entire shopping cart of pills and powders just to function. But do you?In this episode, I'm zooming out and taking a common-sense approach to supplements: no hype, no magic wands, just practical guidance to help you figure out what your body actually needs.In this episode:Why food always comes first — and what "bioavailability" actually means for youThe questions to ask yourself before buying any supplementWhy blood work is your best friend (and how to advocate for the panels you want)What to look for on the label — and the red flags that should make you pauseThird-party testing explained: NSF, USP, and Informed ChoiceThe 5 supplements most commonly recommended for women in perimenopause and menopause: protein, creatine, vitamin D, magnesium, and omega-3sWhy more is NOT always better (a cautionary tale about B6)The truth about chia seeds and omega-3s (spoiler: it's not apples to apples)How to choose where to start based on your own goalsEpisodes Discussed:5 Things You Need to Know Before You Take SupplementsHow to Choose Seafood and Avoid the Rare Ciguatera Poisoning I ContractedProtein: A Common Sense Guide for Women in Perimenopause & MenopauseCreatine, Brain Fog, and Muscle Loss: What Every Woman in Perimenopause Should KnowMuscle cramps, fatigue, headaches and stressed? This natural mineral may help.My latest recommended ways to nourish and move your body, mind and spirit: Nourished Notes Bi-Weekly Newsletter30+ Non-Gym Ways to Improve Your Health (free download)Connect with Amy: GracedHealth.com Instagram: @GracedHealthYouTube: @AmyConnell

Sports medicine physician,endurance athlete and 1% Better Podcast host  - Dave Lipman - checks in for a wide-ranging conversation covering the realities of podcasting, the future of endurance technology, recovery methods, supplements, sleep tracking, heat adaptation, longevity trends, GLP-1s, peptides, and where the line should be drawn between performance enhancement and fair competition. Dave Lipman Links: Instagram: https://www.instagram.com/drdavidlipman/ 1% Better Podcast Instagram: https://www.instagram.com/onepercentbetterpod/| 1% Better Podcast on Spotify: https://open.spotify.com/show/4bG2U3dciEduX8c3PUtkrQ Matt Fox Links: Instagram: https://www.instagram.com/mattinglisfox/ Coaching: https://www.sweatelitecoaching.com/ Supporters Club: https://www.sweatelite.co/supporters YouTube: https://www.youtube.com/@SweatElite Matt welcomes Dave back to the podcast and the pair begin by discussing the realities of producing endurance content. They talk about the challenges of scheduling guests, dealing with cancellations and technical issues, recording in person versus remotely, and why some of the best conversations happen when the host and guest don't know each other particularly well beforehand. Dave also shares his podcast inspirations, what he currently listens to, and the endurance personalities he would most like to interview. The conversation then shifts toward the future of endurance performance technology. Dave discusses continuous lactate monitoring, multi-analyte sensors capable of tracking biomarkers such as glucose, ketones, cortisol, and hormones, as well as emerging ventilation and respiratory wearables. They explore whether future devices will be able to separate metabolic stress from mechanical and neuromuscular load, creating more useful insights than current metrics alone. Matt and Dave discuss the balance between useful data and over-analysis, touching on sleep tracking, orthosomnia, and how athletes can become overly reliant on wearable feedback. Dave explains why subjective feel still matters and why training should ultimately enhance enjoyment rather than create more stress. The discussion moves into supplements, with Dave outlining his practical framework for evaluating evidence and deciding what is worth using. They cover bicarbonate products such as Maurten Bicarb and Nomio, creatine, beta-alanine, beet nitrates, taurine, and the supplement trends currently gaining traction in endurance sport. Recovery strategies are another major focus. Dave reviews the evidence surrounding ice baths, sauna use, heat adaptation, active versus passive heat exposure, and how timing these interventions incorrectly may blunt training adaptations. They also discuss sweat rate adaptations, the interaction between heat and altitude training, and examples of accidental training breakthroughs that emerged from environmental stress. The final section of the conversation examines the rapidly growing longevity and biohacking space. Matt and Dave discuss Bryan Johnson, GLP-1 medications, peptides, anti-aging interventions, anti-doping gray areas, and whether amateur athletes should be held to different standards than professionals. The discussion expands into super shoes, emerging performance technologies, and how the sport may need to adapt as new forms of enhancement become increasingly accessible. Episode Chapters 00:00 Welcome Back Dave 01:01 Podcasting Struggles 02:59 Remote vs In Person 05:06 Editing Norwegian Method 06:56 Podcast Inspirations 07:58 What We Listen To 12:26 Dream Guests List 13:51 Better Interview Flow 16:43 Future Endurance Tech 19:53 Continuous Biomarkers 21:55 Mechanical Load Insights 27:06 Cortisol and Lactate Nuances 31:24 Lactate Compartments 32:56 Tech and Overthinking 36:06 Train for Enjoyment 36:44 Sleep Tracking Pitfalls 40:13 Supplements Framework 47:21 Creatine, Beta-Alanine, and Beets 53:44 Taurine and Trends 56:31 Ice Baths Net Effect 01:02:37 Sauna Heat Adaptation 01:05:52 Heat Training Benefits 01:06:28 Sweat Rate Tradeoffs 01:07:30 Active vs Passive Heat 01:08:38 Heat Plus Altitude Synergy 01:09:15 Accidental Breakthrough Block 01:12:05 Longevity and Bryan Johnson 01:13:15 Complex Systems and Lifestyle 01:17:28 GLP-1s and Doping Rules 01:22:39 Peptides Gray Market Risks 01:23:44 Amateur Standards and Fairness 01:26:28 Super Shoes and Gray Areas 01:33:22 Wrapping Up and Podcast Plug

In this episode Tara answers questions from women in the Life Transformer Plan covering everything from handling social events and alcohol choices to staying motivated with workouts. She also shares practical advice on supplements, mindset, injury modifications, and how to stay on track without overcomplicating the process. What You Will Learn In This Episode: Choosing the food and drink that suit your goals Getting started with workouts Coping when life is hectic Exercise form and modifications Changing weight-loss goals Supplements Tara recommends And More   How To Contact Tara Hammett: tarahammett.com Facebook  

Recent scientific research reveals that creatine monohydrate's benefits extend far beyond muscle growth. In addition to enhancing exercise performance, studies are highlighting its potential to improve brain function, energize immunity, and support menopausal health. Karolyn talks to Karen Todd, a Registered Dietitian and Strength and Conditioning Specialist. They will profile this important nutrient by talking about its benefits, its safety profile, and how to take it as a dietary supplement.Five To Thrive Live is broadcast live Tuesdays at 7PM ET and Music on W4CS Radio – The Cancer Support Network (www.w4cy.com) part of Talk 4 Radio (www.talk4radio.com) on the Talk 4 Media Network (www.talk4media.com).Five To Thrive Live Podcast is also available on Talk 4 Media (www.talk4media.com), Talk 4 Podcasting (www.talk4podcasting.com), iHeartRadio, Amazon Music, Pandora, Spotify, Audible, and over 100 other podcast outlets.

In this episode, we answer your questions in a live Q&A covering some of the most common topics in fat loss, muscle building, and long-term health. From the truth about menopause belly and calorie deficits to creatine, body recomposition, and weekend overeating, we cut through the confusion and focus on what actually matters. If you've ever wondered whether you're eating too little, how often you should strength train, or if popular diets like carnivore are worth it, this episode is packed with practical, evidence-based answers.We talk about:-The truth about menopause belly and fat loss after 40-How the body adapts over time-Whether you can be eating too little and still struggle with weight loss-Progressive overload and muscle growth-The benefits of tracking macros-Creatine, body recomposition, and strength training-The role of NEAT in fat loss-Popular nutrition trends and whether they're worth itTime Stamps: 0:00 Introduction1:24 losing fat during menopause6:50 are you actually in a calorie deficit?13:13 what's the deal with creatine?14:43 strength training frequency19:05 is starvation mode real?22:49 handling exercise on a long vacation25:01 building muscle after big weight loss26:09 growing your glutes27:13 thoughts on Liquid IV31:01 is carnivore worth it?36:32 how much does NEAT matter?40:55 is body recomp possible?45:02 gym etiquette question47:08 does IIFYM work?CONNECT WITH KAIT & MAV:Get 1:1 coaching here: https://go.elev8coaching.net/weight-loss-journeyGet our weekly emails: https://go.maverickonlinecoaching.net/mailing-listEbook: https://go.elev8coaching.net/consistency-book Hosted on Acast. See acast.com/privacy for more information.

Your Brain Uses 20% of Its Creatine Just to Think | Podcast #479  

Are you asking ChatGPT, AI, or Facebook groups what supplements your gymnast needs?Maybe your gymnast is tired, sore, injured, getting sick often, struggling to recover, or not gaining strength — and as a parent, you just want to help.So you ask: Does she need magnesium? Iron? Creatine? Electrolytes? Protein powder? A multivitamin?But when it comes to pediatric and adolescent gymnasts, supplements are not that simple.In this episode, Christina continues her four-part series on what ChatGPT and AI do not know about your gymnast's nutrition, and today's focus is supplements.Because while AI can give you a polished answer or a list of recommendations, it cannot accurately assess whether your gymnast actually needs those supplements.It does not know if she is eating enough, growing appropriately, recovering well, fueling consistently, or whether her symptoms are actually signs of under-fueling.And this matters.Because no supplement can make up for not eating enough.Many of the things parents try to fix with supplements — fatigue, soreness, poor recovery, frequent illness, injuries, slow strength gains, or stalled progress — are often connected to under-fueling, not a missing supplement.In this episode, Christina breaks down why “food first” matters, why supplement recommendations require context, and why individualized nutrition support is so important for growing gymnasts.In this episode, we cover:❗ Why AI and online searches cannot determine your gymnast's supplement needs❗ Why supplements should never replace eating enough food❗ Why fatigue, soreness, injury, and poor recovery are often signs of under-fueling❗ Why creatine, protein powder, iron, magnesium, electrolytes, and multivitamins all require individualized context❗ Why iron supplements can be harmful if your gymnast does not actually need iron❗ Why supplement quality and third-party testing matter❗ Why social media supplement recommendations can be misleading❗ Why parents may spend more on random supplements than they would on individualized support❗ What parents should ask instead of, “What supplement does my gymnast need?”AI may be able to generate a supplement recommendation.But it cannot evaluate your gymnast's growth, fueling, recovery, labs, training demands, injury history, symptoms, and health context the way an experienced pediatric and adolescent sports dietitian can.Your gymnast does not need a random supplement stack from the internet.She needs the right nutrition foundation first.Enough food. Enough carbs. Enough protein. Enough calories. Enough consistency.And then, if there are true gaps, supplements can be used intentionally and individually.Because supplements are just that — supplements.They are meant to fill in what is missing, not fix under-fueling.So if your gymnast is tired, sore, injured, sick often, struggling to get stronger, or not recovering well, the better question is not, “What supplement should she take?”The better question is, “Is she eating enough to support what her body is being asked to do?”And that requires individualized support, not a generic AI answer.Links & ResourcesThe Balanced Gymnast® Program (Level 5–10)Connect with Christina on Instagram @the.gymnast.nutritionist christinaandersonrdn.com

In this episode, we answer your questions in a live Q&A covering some of the most common topics in fat loss, muscle building, and long-term health. From the truth about menopause belly and calorie deficits to creatine, body recomposition, and weekend overeating, we cut through the confusion and focus on what actually matters. If you've ever wondered whether you're eating too little, how often you should strength train, or if popular diets like carnivore are worth it, this episode is packed with practical, evidence-based answers.We talk about:-The truth about menopause belly and fat loss after 40-How the body adapts over time-Whether you can be eating too little and still struggle with weight loss-Progressive overload and muscle growth-The benefits of tracking macros-Creatine, body recomposition, and strength training-The role of NEAT in fat loss-Popular nutrition trends and whether they're worth itTime Stamps: 0:00 Introduction1:24 losing fat during menopause6:50 are you actually in a calorie deficit?13:13 what's the deal with creatine?14:43 strength training frequency19:05 is starvation mode real?22:49 handling exercise on a long vacation25:01 building muscle after big weight loss26:09 growing your glutes27:13 thoughts on Liquid IV31:01 is carnivore worth it?36:32 how much does NEAT matter?40:55 is body recomp possible?45:02 gym etiquette question47:08 does IIFYM work?CONNECT WITH KAIT & MAV:Get 1:1 coaching here: https://go.elev8coaching.net/weight-loss-journeyGet our weekly emails: https://go.maverickonlinecoaching.net/mailing-listEbook: https://go.elev8coaching.net/consistency-book

If foods you've eaten for years are suddenly leaving you bloated, uncomfortable or rushing to the loo, fluctuating hormones could be to blame. Liz explores how perimenopause can activate digestive discomfort and looks at ways to support the gut lining to improve symptoms.Plus: how to avoid injuries from strength training, managing acid reflux and indigestion, evening heart palpitations and can using a sauna reduce dementia risk?In this episode:•Are hormone fluctuations making me gluten intolerant?•Ways to manage heartburn and indigestion•Will using a sauna reduce my risk of dementia?•Advice for avoiding injuries when strength training•Why is my heartbeat so loud at night? Links mentioned in the episode:•Creatine - https://lizearlewellbeing.com/?s=creatine •Butyrate - https://lizearlewellbeing.com/?s=butyrate•The Good Gut Guide - https://shorturl.at/hwfDb•British Heart Foundation information on PPIs - https://www.bhf.org.uk/informationsupport/heart-matters-magazine/medical/drug-cabinet/proton-pump-inhibitorsGet in touch with a question for Liz: •Email: podcast@lizearlewellbeing.com•WhatsApp: 07518 471 846More from Liz:•Order Liz's new book – How to Age- https://www.amazon.co.uk/How-Age-Supercharge-Health-Better/dp/1399723715•A Better Second Half- https://www.amazon.co.uk/dp/1399723677?_encoding=UTF8&qid=1695723884&sr=8-1&linkCode=sl1&tag=lizearlewellb-21&linkId=5eefa1edb4d033e84befc25728bebcf0&language=en_GB&ref_=as_li_ss_tl•Follow Liz on Instagram- https://www.instagram.com/lizearleme/?hl=en•Follow Liz Earle Wellbeing on Instagram- https://www.instagram.com/lizearlewellbeing/?hl=enHost: Liz EarleProducer: Lynnike Swerts (Fresh Air Production)Social Media Manager: Naomi van GeelenContent Writer: Lucy ParleyHead of Brand: Ellie Smith Some links may be affiliate links, which help support the show at no extra cost to you. Read our Affiliate Policy for more information. Hosted on Acast. See acast.com/privacy for more information.

Today, we're talking about sermorelin peptide therapy, an emerging peptide therapy option that's gaining attention for its potential benefits in anti-aging, muscle health, and overall vitality.  Whether you've heard about it before or are learning about it for the first time, this episode will break down exactly what sermorelin is, how it works, and why some people are turning to it for a boost in their health. Read the Full Episode Transcript: https://pepties.com/sermorelin/ Related Links/Products Mentioned: Peptide Podcast Partners Page https://pepties.com/partners/ Buy Peptides online at BioLongevity Labs: Use our link and enter COUPON CODE: PEPTIDEPODCAST  at checkout to receive 15% off your total order:  https://go.biolongevitylabs.com/SH5C Momentous Supplements (we use Creatine, Vital Aminos, Whey Protein) https://crrnt.app/MOME/OqGQOxGA LMNT – More Salt, Not Less.  https://elementallabs.refr.cc/default/u/johnjavit Thorne Supplements (we use Omega-3 with CoQ10, Red Yeast Rice, Zinc) https://get.aspr.app/SH1KvW Organifi Creatine and Shilajit Gummies http://rwrd.io/rlbkajm?c MitoZen (methylene blue for Cognitive Function, Anti-Aging, Mental Clarity) https://www.mitozen.com/ref/cnlwiztypt/ For skin and hair health (Copper Tripeptide-1)  Visit Luminose by Entera for an exclusive offer for Peptide Podcast listeners!  ** Promo code PEPTIDEPODCAST at checkout for 10% off an order or 10% off the first month of a subscribe-and-save. ** https://www.enteraskincare.com/?rfsn=8906839.f93c72 NAD+ Push Patch: https://www.pushpatch.com/

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Episode 113 is live! With Jeff still out in the field, Grant and Tres take over the controls for a classic freewheeling episode packed with staff brief shenanigans, college football talk, Bitcoin updates, Texas Tech headlines, lifting questions, creatine myths, training mistakes, upcoming Strength Co. projects, Wisconsin adventures, and plenty of the organized chaos that makes The Okay Podcast what it is. If you've ever wondered whether supplements matter, what gym mistakes are actually holding people back, this episode is for you.Podcast Hosts:Grant Broggi: Marine Veteran, Owner of The Strength Co. and Starting Strength Coach.Jeff Buege: Marine Veteran, Outdoorsman, Football Fan and LifterTres Gottlich: Marine Veteran, Texan, Fisherman, Crazy College Football Fan and LifterJoin the Slack and Use code OKAY:⁠https://buy.stripe.com/dR6dT4aDcfuBdyw5ks⁠Check out BW Tax: ⁠https://www.bwtaxllc.com⁠BUY A FOOTBALL HELMET:⁠⁠⁠⁠https://www.thestrength.co/mrhelmet/?utm_source=The+Okay+Podcast&utm_medium=Podcast&utm_campaign=Okay_Pod⁠Timestamps: 00:00 - Intro08:52 - Staff Brief18:19 - Outlying Stations24:18 - Most Overrated Lift31:19 - Creatine41:08 - Dad Splits44:12 - Wisconsin49:20 - PCS01:00:47 - College World Series01:08:15 - Texas Tech Debate01:16:38 - Sick Kids & Being A Dad01:23:34 - New Trees01:33:13 - Chili Cook Off Recap01:39:04 - Ghost Tours

Introduction Dr. Arreaza: Hello, everyone, today we continue with our series about sleep. I invite you to listen to Moira Wilson on Episodes 220 and 221 about the approach of insomnia and CBT-I in adults. Today we will discuss not only what to do, but also why it works. We frequently hear advice like ‘get more sleep,' but we need to dig deeper into the physiology behind it. So, Dr. Kim and Dr. Carlisle are here to briefly explain the physiology of sleep and what we can do to support better sleep. But before we start, let's welcome Dr. Carlisle, who recently matched to our program. He will start his residency soon, and Dr. Kim, who will soon become a PGY2, welcome doctors.  Dr. Carlisle: [Introduce yourself].  Dr. Kim: [Introduce yourself].  Dr. Arreaza: Let's start simple. Why does sleep matter clinically? Why Sleep Matters Dr. Kim: Sleep is one of the most important biological processes we have. It's not passive; it's highly active and tightly regulated. It affects cognition, metabolism, immune function, cardiovascular health, and hormonal balance. When sleep is disrupted, you see downstream effects in almost every organ system. Dr. Carlisle: Yeah, and one thing I always emphasize is that sleep deprivation isn't just about feeling tired. It actually puts you in a physiologic state that's very similar to being intoxicated. There are studies showing that being awake for about 24 hours can impair cognitive performance to a level comparable to being above the legal driving limit for alcohol. Dr. Arreaza: That's actually kind of scary when you think about it.  Dr. Carlisle: It really is. Another way to think about it is sleep deprivation doesn't just make you slower; it actually changes how you make decisions. People become more impulsive and less risky. And in medicine, we see that translates into increased medical errors, decreased attention, and poor decision-making. So, from a clinical standpoint, sleep isn't optional; it's foundational. Dr. Kim: Delay caffeine (but not too late), avoid alcohol, and focus on behavioral strategies (put away your phone 1 hour before bedtime).  Dr. Carlisle: And sleep is the foundation of performance. If sleep is off, everything else is compensating. Dr. Kim: And even beyond cognition, even one night of poor sleep can impair immune function and shift hormones that regulate hunger, which is why people tend to crave more food when they're sleep deprived. Dr. Arreaza: I think it's wise to dispel the myth of the “Russian Sleep Experiment”, have you heard about it? Dr. Carlile-Dr Kim: [reaction] Dr. Arreaza: The “Russian Sleep Experiment” is an internet horror story claiming Soviet scientists kept prisoners awake for several weeks using a gas. They developed extreme paranoia, violence, and self-mutilation. Then, the experiment got out of control, the subjects became unrecognizable, they refused to sleep, continued to deteriorate, and went insane. Even though the story went viral in 2010, it is fictional (reaction), with no real evidence that it really happened. So, it is just a made-up horror story. But there are some real studies about sleep deprivation in humans.  Dr Kim: Yes, the most famous case was Randy Gardner (1964) who stayed awake for 11 days. He developed hallucinations, memory problems, and mood changes. He recovered after sleep (no permanent “madness”). Dr. Carlisle: Sure, but as I mentioned before, even one night without sleep significantly reduces performance and accuracy. Dr. Kim: Another myth we fall into is “catching up on sleep”. It is a myth! Sleep Architecture Dr. Arreaza: Sleeping is a state when you reset your brain and your energy, but what actually happens during sleep? Dr. Carlisle: Sleep cycles between non-REM and REM stages. Non-REM sleep, especially deep, slow-wave sleep, is where physical restoration happens. That's when you get growth hormone release, tissue repair, and metabolic recovery. Dr. Kim: And one of the most fascinating things is what happens in the brain during that deep sleep. The space between brain cells actually expands, which allows cerebrospinal fluid to circulate and clear out metabolic waste. Dr. Carlisle: That's the glymphatic system. And what's interesting is that this clearance is most active during deep sleep (Stage 3, Delta waves). It clears neurotoxins like beta amyloid, which is one reason chronic sleep deprivation is linked to neurodegenerative diseases, such as Alzheimer's disease.  Dr. Arreaza: So, your brain is basically cleaning itself while you sleep. The “glymphatic system” is relatively new. It was described in 2010, and it clears substances like beta-amyloid, which is linked to Alzheimer's disease. Dr. Carlisle: Exactly. Then REM sleep is more focused on brain function. That's where memory consolidation, emotional processing, and learning really happen. Dr. Kim: And REM sleep tends to occur more in the second half of the night. So, when people cut their sleep short, they lose a lot of that REM sleep, which affects mood, focus, and overall cognitive function. What Drives Sleep Dr. Arreaza: So, what actually makes us feel sleepy? Dr. Kim: There are two main processes. The first is the homeostatic drive, where adenosine builds up in the brain the longer you're awake, creating sleep pressure.  Dr. Carlisle: And the second is your circadian rhythm, which is controlled by your brain's internal clock and influenced mainly by light exposure. Dr. Arreaza: So, in summary, one process depends on how long you've been awake, and the other process depends on your body's own timing.  Dr. Carlisle: Exactly. I think of it as pressure and timing. Adenosine builds pressure, and your circadian rhythm determines when that pressure gets released. Dr. Kim: And when those two systems are aligned, sleep happens naturally. When they're out of sync, that's when people start having issues.  Morning Routine Dr. Arreaza: Let's talk about practical tips. The morning seems to be a key element in our sleep. What can we do in the mornings to help us sleep at night? Dr. Carlisle: Morning sunlight, without a doubt. Getting light exposure within the first 30 to 60 minutes of waking helps anchor your circadian rhythm. Dr. Kim: And outdoor light is much stronger than indoor light, even on cloudy days. Dr. Carlisle: The mechanism is that light activates specialized retinal cells that signal your brain's clock. That sets the timing for cortisol release in the morning and melatonin release later at night. Dr. Kim: And it also increases dopamine early in the day, which helps with mood, motivation, and focus. Dr. Carlisle: So, you're not just waking up; you're setting up your entire day's physiology. Caffeine and Hydration Dr. Arreaza: Light exposure; I like the idea. That's why phototherapy works for any kind of depression, not only seasonal depression. What other suggestions can you give us about our morning routine?  Dr. Carlisle: Hydration first thing in the morning helps restore plasma volume and improve alertness since we're mildly dehydrated overnight. Dr. Kim: It is also a good idea to add electrolytes to the water. And caffeine timing is huge. If you drink it right when you wake up, you're interfering with your natural adenosine cycle. Dr. Carlisle: Exactly. Caffeine blocks adenosine receptors, but it doesn't remove adenosine. So later in the day, when caffeine wears off, all that built-up adenosine hits at once, and that's what causes the crash. And that's why some people feel wired but still tired because the underlying sleep pressure is still there, just being masked by the caffeine.  Dr. Arreaza: So, what should people do instead? (I say people because I personally don't drink coffee, and occasionally I drink caffeine) Dr. Kim: People should wait about 60 to 90 minutes before having caffeine.   Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week!  _____________________ References: 1. Williamson AM, Feyer AM. Moderate sleep deprivation produces impairments in cognitive and motor performance equivalent to legally prescribed levels of alcohol intoxication. Occup Environ Med 2000;57(10):649-655. 2. Xie L, Kang H, Xu Q, et al. Sleep drives metabolite clearance from the adult brain. Science. 2013;342(6156):373-377. 3. Walker MP. Why We Sleep: Unlocking the Power of Sleep and Dreams. Scribner; 2017. 4. McMorris T, Harris RC, Swain J, et al. Effect of creatine supplementation and sleep deprivation on cognitive performance. J Sports Sci. 2006;24(3):305-313. 5. Turner CE, Byblow WD, Gant N. Creatine supplementation enhances corticomotor excitability and cognitive performance during sleep deprivation. J Sleep Res. 2015;24(3):307-315. 6. Gordji-Nejad A, Matusch A, et al. Creatine supplementation and brain energy metabolism during sleep deprivation. Sci Rep. 2024;14:54249. 7.  Wienecke E, Nolden C, et al. Magnesium and sleep quality: systematic review. *Med Res Arch.2021. 8. Theme song, Works All The Time by Dominik Schwarzer, YouTube ID: CUBDNERZU8HXUHBS, purchased from https://www.premiumbeat.com/. Even without trying, every night you go to bed a little wiser. Thanks for listening to Rio Bravo qWeek Podcast. We want to hear from you, send us an email at RioBravoqWeek@clinicasierravista.org, or visit our website riobravofmrp.org/qweek. See you next week!

With so many supplements marketed to runners, it's easy to wonder what's actually worth taking. In this episode, we cut through the noise and focus on a few supplements that have strong research behind them—while emphasizing that no supplement can replace consistent training, good nutrition, quality sleep, and proper recovery.We break down the Three Cs: Carbohydrates, Creatine, and Caffeine.First, we discuss why many runners are underfueling and how carbohydrates play a critical role in performance, recovery, and endurance. Next, we explore creatine monohydrate, one of the most researched supplements available, and its benefits for strength, recovery, and overall health. Finally, we cover caffeine, including how it can improve performance, common dosing guidelines, and why personal tolerance matters.We also briefly touch on vitamin D, magnesium, omega-3s, and collagen, and discuss when they may be worth considering.In This Episode:Why supplements should never replace the fundamentalsHow carbohydrates support performance and recoveryThe benefits of creatine for runnersHow caffeine can enhance enduranceWhen other supplements may be helpfulAvoiding the optimization trap and keeping things simple03:53 The Three Cs 09:59 Fueling During Runs14:29 Carb Targets And Gut Training20:16 Women Over 40 And Carbs25:03 Adjusting Fuel To Effort28:31 Creatine Explained41:14 Monohydrate and Daily Dose43:25 Caffeine Performance Basics46:23 Dosing and GI Timing47:33 Metabolism and Jitters50:29 Sleep and Tolerance Tradeoffs54:12 Race Day Caffeine Rules56:54 Vitamin D Testing59:34 Magnesium for Cramps01:03:38 Omega 3 Benefits01:05:26 Collagen Versus ProteinGain access to my new secret podcast, Unbreakable: The Runner's Guide To Injury-Proofing Your Body After 40. Click here: https://www.realliferunners.com/secretJoin the Team! -->  https://www.realliferunners.com/team Thanks for Listening!!Be sure to hit FOLLOW on Apple Podcasts, Spotify, or your favorite podcast player Leave a review on Apple Podcasts. Your ratings and reviews really help and we read each one!Come find us on Instagram and say hi! Don't forget: The information on this website is not intended to treat or diagnose any medical condition or to provide medical advice. It is intended for general education in the areas of health and wellness. All information contained in this site is intended to be educational in nature. Nothing should be considered medical advice for your specific situation.

Creatine causes cancer to spread — that headline is built on a real mouse study. But what does the human data actually say? In this solo explainer, Dr. Robert Lufkin breaks down both halves of the science behind the most studied supplement on the planet.He walks through the 2021 mouse metastasis study behind the viral claim, the surprising evidence that creatine actually powers the immune cells that HUNT cancer (CD8 T cells and, per new UCLA research, dendritic cells), and what the human data — HCAs, NHANES, and the 2025 safety review — really shows. The verdict is more nuanced, and more reassuring, than the headline suggests.Chapters:00:00 — Introduction00:46 — Why This Question Exists01:32 — The Scary Half (2021 Study)02:17 — How Creatine Fuels Tumor Spread03:03 — Creatine Fights Cancer Too03:48 — UCLA June 2026 Dendritic Cells04:35 — Tumor Suppressor or Fuel?05:21 — What Human Data Shows (HCAs)06:08 — NHANES & 2025 Safety Review06:55 — The Honest Caveat07:42 — The TakeawayKey takeaways:The scary headline comes from a 2021 mouse study where dietary creatine promoted metastasis via the MPS1 → SMAD2/3 → TGF-beta pathway — in mice with established, aggressive tumors.The same metabolism fuels your immune system: creatine is essential for CD8 "killer" T cells and the dendritic cells that direct them.In a controlled human trial, creatine did NOT drive carcinogen (HCA) formation.NHANES population data links higher dietary creatine to LOWER cancer risk, and the 2025 safety review calls the human cancer-risk claim "not substantiated."Healthy adults: the human evidence does not support avoiding creatine. Active or metastatic cancer: pause and talk to your oncologist. Always choose third-party tested creatine monohydrate.Studies & sources:Zhang et al., Cell Metabolism 2021 — Creatine promotes cancer metastasis via Smad2/3Geng et al., Int. J. Mol. Sci. 2024 — The multifaceted role of creatine metabolismDi Biase et al., J. Exp. Med. 2019 — Creatine and CD8 T cell antitumor immunityKang et al., iScience 2026 (UCLA) — Creatine and dendritic cell activationPereira et al., Amino Acids 2015 — Creatine and heterocyclic aminesNHANES 2017–2020 — Dietary creatine and cancer riskAntonio et al., Frontiers in Nutrition 2025 — Common safety concerns regarding creatine

This special Creatine Compilation brings together expert insights from Rachel DeVaux, Dr. Abbie Smith-Ryan, and Andrew Koutnik on one of the most researched supplements in health and fitness. Through highlights from these conversations, we explore how creatine supports muscle growth, recovery, brain health, metabolic health, performance, and healthy aging. We also discuss dosing, common misconceptions, who can benefit most from creatine supplementation, and why it's becoming an increasingly important tool for women, athletes, and anyone looking to optimize their long-term health. → Leave Us A Voice Message! Topics Discussed: → Why is creatine one of the most researched supplements available? → How does creatine support muscle, strength, and recovery? → What role does creatine play in brain health and cognition? → Why are more women being encouraged to take creatine? → How much creatine do you actually need? → Is creatine safe for long-term use? → Can creatine support metabolic health and healthy aging? → What are the biggest misconceptions about creatine? → How can creatine fit into a whole-foods lifestyle? → Who stands to benefit most from creatine supplementation? Sponsored By:  → Function | Check your health the way I do. Function provides 160+ lab tests for $1/day and member pricing on MRI and CT scans. Join at https://functionhealth.com/bewellbykelly and use code BEWELL25 for a $25 credit. → Be Well By Kelly Protein Powder & Essentials | Get $10 off your order with PODCAST10 at https://bewellbykelly.com. → LMNT | Get a free 8-count Sample Pack of LMNT's most popular drink mix flavors with any purchase at https://drinklmnt.com/Kelly. Find your favorite LMNT flavor, or share with a friend. → Hiya | Get 50% off your first order at https://hiyahealth.com/KELLY → Minnow | Shop minnow's new apré-ski capsule collection at https://shopminnow.com and enter code MEETMINNOW15 at checkout to receive 15% off your first order. Timestamps:  → 00:00:00 - Introduction → 00:01:15 - Rachel DeVaux: Why Creatine Is More Than A Muscle Supplement → 00:05:20 - Creatine For Strength, Recovery + Performance → 00:09:18 - The Benefits Of Creatine For Women → 00:15:58 - Dr. Abbie Smith-Ryan: How Creatine Supports Brain Health → 00:20:32 - Creatine, Aging + Longevity → 00:29:08 - How Much Creatine Do You Actually Need? → 00:34:15 - Common Creatine Myths Explained → 00:42:35 - Creatine, Cognition + Alzheimer's Research → 00:47:52 - Creatine For Perimenopause + Women's Health → 00:52:40 - Is Creatine Safe For Long-Term Use? → 00:59:05 - Andrew Koutnik: Who Benefits Most From Creatine Supplementation? → 01:01:19 - Best Practices For Taking Creatine → 01:06:10 - Creatine, Mood + Mental Health → 01:10:49 - Choosing A High-Quality Creatine Supplement → 01:13:47 - Creatine, Metabolic Health + Performance → 01:19:03 - Metabolic Flexibility + Ketosis → 01:22:42 - Final Thoughts Further Listening:  → Building Muscle, Protecting Metabolism, + Simplifying Dinner | Rachael DeVaux → The Truth About Creatine for Women: Strength, Hormones, + Brain Health | Abbie Smith → Why You're Stuck: Hunger, Hormones + Metabolic Fixes | Dr. Andrew Koutnik Check Out: → Abbie Smith Ryan  → Website  → Rachel DeVaux   → Website  → Andrew Koutnik  → Website  Check Out Kelly: → Instagram → Youtube → Facebook

June 10, 2026: Your daily rundown of health and wellness news, in under 5 minutes. Today's top stories: AG1 launches AG1 Pro combining flagship greens with creatine, Calcium-HMB, and muscle health ingredients as creatine moves from sports nutrition to mainstream longevity supplement Therabody launches CryoTherm Palm handheld thermoregulation device tested with USC and IMG athletes, expanding from recovery into performance enhancement Stars + Honey raises $24M from VMG Partners targeting $50M revenue, combining collagen peptides with protein at intersection of beauty, wellness, and nutrition More from Fitt: Fitt Insider breaks down the convergence of fitness, wellness, and healthcare — and what it means for business, culture, and capital. Subscribe to our newsletter → insider.fitt.co/subscribe Work with our recruiting firm → https://talent.fitt.co/ Follow us on Instagram → https://www.instagram.com/fittinsider/ Follow us on LinkedIn → linkedin.com/company/fittinsider Reach out → insider@fitt.co

Most women think they need to lose weight to change their body… but what they actually want is body recomposition.In this episode of the Gym Confidence Series, we're breaking down what body recomp actually means, why strength training changes your shape, and why the “toned” look so many women want actually comes from building muscle - not starving yourself or doing endless cardio.I also talk about the difference between fat loss and muscle building, why the scale is not the full picture, and how so many women are chasing smaller bodies instead of stronger, healthier, more sustainable results. I also explain maintenance calories, calorie deficits, beginner muscle growth, and why consistency matters so much more than extremes.This episode is all about helping you understand what is ACTUALLY happening inside your body when you start lifting weights, eating enough protein, and training consistently … without overcomplicating the process (of course!)In this episode, we cover:what body recomposition actually iswhat “toned” really meanswhy muscle changes your body shapewhy strength training matters for womenmaintenance calories explained simplycalorie deficits without extremeswhy beginners often see faster progressthe biggest mistakes women make with fat losswhy consistency beats crash dieting every timeLinks/Resources:SHOP UFYF merchandiseGrab your FREE Body Recomp Meal Prep and get the UFYF NewsletterSHOP Kion - my favorite Protein, EAA's and Creatine!Listen to the Girls with Opinions PodcastJoin FIT CLUB, my monthly membership with workouts you can do at home or the gymConnect with me on Instagram @kristycastillofit and @unfuckyourfitnesspodcastJoin my FREE Facebook group, Unf*ck Your FitnessClick HERE for my favorite fitness & life things!Send me a text with episode ideas or just to say hi! Support the show

If you have ever stood in front of your refrigerator wondering how on earth you are supposed to eat 100 grams of protein a day without turning mealtime into a second job, this episode is for you. In this conversation, Dr. Fiona Lovely welcomes Liz Baker Plosser, former Editor-in-Chief of Women's Health magazine and author of Own Your Morning. Liz has spent more than two decades translating health research for women, and she is here to cut through the noise on protein, essential amino acids, and creatine for midlife. Liz and Dr. Lovely discuss why our bodies become less efficient at using protein as estrogen declines, and why aiming for 100 grams or more daily is not about diet culture but about protecting muscle, brain function, and overall energy. They break down the distinct roles of essential amino acids for repair and recovery versus creatine for strength and cognitive performance, including new research showing creatine can help sharpen the brain after a broken night of sleep. Liz also shares how she uses a simple morning supplement routine as an insurance policy, allowing her to live flexibly without obsessing over every meal. For any woman who has felt overwhelmed by the conflicting advice on social media or dismissed midlife fatigue as normal, this episode offers a clear, science-backed path forward. To get the essential amino acid supplement we speak about in this episode go to:  getkion.com/lovely to get 20% off! You can find Liz Baker Plosser on Instagram @lizplosser and on her Substack, Best Case Scenario, at substack.lizplosser.com.   Thank you to our sponsors for this episode:

Dr Mike T. Nelson returns to set the fitness industry ablaze with the claim that Zone 2 cardio is overrated and not particularly effective for most people.Mike goes into detail on:Why he feels Zone 3 cardio is substantially more effective and efficient than Zone 2What the evidence and research says about Zone 2 and Zone 3The cardiovascular adaptations actually happening in Zone 2 and Zone 3What Zone 3 cardio should look and feel likeMike's 6-minute Zone 3 training protocolWhy step count is still importantShould most lifters worry about the interference effectMike's thoughts on The Enhanced GamesDoes high-dose creatine help when sleep deprivedAnd much moreInstagram: @drmiketnelsonCHAPTERS00:50 Why Skip Zone 202:42 Zone 3 For Lifters05:01 General Population Reality06:42 Elite Athlete Context12:02 Is Zone 2 Still Useful15:18 Walking, Steps, and Longevity23:30 Zone 3 Talk Test26:56 The 6-Minute Protocol27:52 VO2 Max Interval Planning29:15 Pacing and RPE32:37 Interference Effect Basics35:46 Women and Cardio Myths41:25 Intensity vs Adaptations44:35 The Enhanced Games Debate53:27 Creatine for Sleep LossSUPPORT THE SHOWIf this episode helped you better understand cardio, conditioning, or performance, you can support the show by:Subscribing and checking out more episodesSharing it on social media (tag me and I'll respond)Sending it to someone who thinks cardio has to mean long, slow sessionsFOLLOW ANDREW COATESInstagram: @andrewcoatesfitnesshttps://www.andrewcoatesfitness.comPARTNERS AND RESOURCESRP Strength App (use code COATESRP)https://www.rpstrength.com/coatesJust Bite Me Meals (use code ANDREWCOATESFITNESS for 10% off)https://justbitememeals.comMacrosFirst – FREE Premium TrialDownload MacrosFirst and during setup select ANDREWKNKG Bags (15% off)https://www.knkg.com/Andrew59676Versa Grippshttps://www.versagripps.com/andrewcoatesTRAINHEROIC – FREE 90-Day Trialhttps://www.trainheroic.com/liftfreeReply to the email you receive (or email trials@trainheroic.com) and let them know Andrew sent you

In this episode the guys break down exactly how to look your best this summer with 30 days or less. They debate personal strategies — carb and water manipulation, peak week bodybuilding tactics, creatine loading, blood flow restriction training for arms and calves, building your abs instead of just leaning out, training rear delts and upper back for the beach, tibialis training for better looking legs, and why switching to whole foods alone will make you look visibly different in 30 days.   MAPS Summer Sale — https://mapsfitnessproducts.com Code: SUMMER40 — 40% off everything (programs, bundles, mods & guides) — June 1–14 only   SPONSOR   Rho Nutrition (liposomal NAD+ & Glutathione) — https://www.rhonutrition.com/discount/MINDPUMP Code: MINDPUMP — 20% off everything. NAD+ raises your baseline energy without stimulants.     LINKS Mind Pump Store: https://mindpumpstore.com  Maps Fitness Products: https://mapsfitnessproducts.com Instagram: @mindpumpmedia   0:00 - Intro 2:02 - Adam's 30-day strategy — push carbs and volume, then taper and peak the final week 9:12 - Creatine loading for muscle fullness — why the scale going up is actually good 10:05 - Spray tans, haircuts and the real reason bodybuilders tan up 13:19 - Sal's strategy — build your abs instead of just leaning out, rear delts & upper back 20:44 - Blood flow restriction for arms and calves — a quarter inch of size in 30 days 22:10 - Justin's strategy — eliminate the extras, clean up the diet, rows and cleans for the yoke 23:43 - Why switching to whole foods alone makes you look visibly better in 30 days

Is your morning routine missing a critical piece for optimal brain function? In this episode of The Ash Said It Show, I sit down with Eli from FluxCo to shatter the outdated myths surrounding one of the most well-researched, yet misunderstood, supplements in history: creatine. While many still associate creatine exclusively with bodybuilding and muscle gain, our conversation reveals why it is actually a powerhouse for daily mental clarity, neuroprotection, and overall cognitive performance. We dive deep into the supplement industry to discuss why FluxCo was created to fill a massive void in the market. Eli explains how the brand is successfully shifting the narrative from "gym-bro" aesthetic to a health-first approach designed for the everyday wellness enthusiast. If you have ever felt overwhelmed by the crowded, confusing supplement aisle, this episode is your roadmap to understanding what actually matters in a high-quality formulation. Eli breaks down the specific, defining elements that separate FluxCo from the generic powders on the shelf, ensuring you know exactly what you are putting into your body for maximum benefit. One of the most valuable parts of our discussion is our mission to debunk the most persistent myths that keep people from experiencing the cognitive benefits of creatine. We tackle the misinformation regarding bloating and dehydration head-on, replacing gym-floor rumors with science-backed facts. Whether you are looking to boost your focus at work or improve your recovery after a workout, Eli's insights provide a clear path forward for integrating this supplement into your life effectively. We also look toward the future, exploring the next major milestones for the FluxCo community and their commitment to education-first health. If you are ready to stop guessing and start optimizing your brain health, listen to this episode to discover why creatine deserves a permanent spot in your daily regimen. Tune in to this episode of The Ash Said It Show to learn why upgrading your supplement game is the simplest step you can take toward a sharper, more energized version of yourself. Web: https://fluxcreatine.com/ Follow: @fluxcreatine About: FluxCo is a performance nutrition brand specializing in high-bioavailability, pharmaceutical-grade micronized creatine. Engineered for athletes, professionals, and high-performers, FluxCo provides the essential fuel required for muscle protein synthesis, physical endurance, and sustained cognitive focus. Why Choose FluxCo? Superior Bioavailability: Our micronized formula ensures faster absorption and maximum digestive comfort, eliminating the "bloat" associated with standard creatine monohydrate. Clean Label Standards: FluxCo products are third-party tested, free from synthetic fillers, artificial sweeteners, and hidden additives. Cognitive & Physical Support: Beyond muscle recovery, FluxCo supports neurological health and mental clarity, helping you maintain a baseline of peak productivity. FluxCo bridges the gap between sports science and daily optimization. Whether you are hitting a new personal best in the gym or tackling a demanding workday, FluxCo provides the consistent foundation needed to reach a state of flow. - Ready to ignite the spark that levels up your entire life? Meet Ash Brown—the American powerhouse, motivational architect, and ultimate hype-woman dedicated to your personal and professional evolution. Ash is far more than a voice in the personal development space; she is a trusted ally who delivers a masterclass in real-talk wisdom and infectious energy. Whether you are navigating a crossroads or ready to scale your grandest ambitions, Ash fuels your journey with a high-octane blend of heart and hustle.

Thank you for joining us for our 2nd Cabral HouseCall of the weekend!   I'm looking forward to sharing with you some of our community's questions that have come in over the past few weeks…   Thank you for tuning into this weekend's Cabral HouseCalls and be sure to check back tomorrow for our Mindset & Motivation Monday show to get your week started off right!   Kim: What would cause my son to cough hard for hours after eating? He has done this for a year. He is 28 and said he is to the point where he just does not want to eat. Should he do the CBO protocol?      Anonymous: Hi Dr Cabral, I came across your podcast a few months ago and have been listening daily to catch up on past episodes for general health education. Thank you for the valuable information you share. I would appreciate your guidance on diet and lifestyle for the following situation. My partner, a 31-year-old male, recently had an eGFR test done, and his result increased from 70 to 77. His father passed away in his 40s due to kidney failure, so this is a concern for us. We live in the Caribbean, where it is humid year-round. He strength trains 3–4 times per week and plays basketball once weekly, but I'm unsure if his cardio levels are sufficient for long-term kidney and overall health.       Christine: Hi Dr. Cabral, Thank you so much for everything you do! Your IHP program and your podcast have been life changing for me. I have a question about creatine. I've noticed when I take it, my appetite completely plummets and food does not even taste good. And when I cut out creatine, the appetite comes back within a day. I take around 1g for reference, and I'm 5'1 and 115 lbs if that needs to be taken into consideration. What could be the possible reasons for this? Thank you! Christine       Tricia: Good morning, Dr Cabral - hope you are well! I take many of your supplements with some being from the longevity line. I'm wondering if it is okay to take these ongoing for years or should we take a few weeks break from time to time? Are they as effective when used long term? The supplements I'm taking are your renewal system, eye health, hair supplements. Thank you for your guidance!      Matt: Hi Dr Cabral, I'm a healthy 45yo, strength train 3x per and 2 days of jiujitsu. I had my first ever episode of AFIB and it occurred about 5 min after taking a growth hormone peptide Tesamorelin. I went to the ER the next day and came out of it on my own within 14 hours of when it started and haven't had an episode since. They ran all kinds of blood work, EKG, CT w contrast for blood clots and all came up clear. They seemed to think it was from excessive caffeine use (300-500mg daily) and bad sleep but weren't really sure on the peptide as there's not enough research. Seems to me that's what triggered it. I stopped caffeine&peptides immediately and have really been trying to dial in my sleep for the past two weeks. Could this be a one off thing or am I more likely to have it happen again?     - - - Show Notes and Resources: StephenCabral.com/3775 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

Welcome back to our weekend Cabral HouseCall shows!   This is where we answer our community's wellness, weight loss, and anti-aging questions to help people get back on track!   Check out today's questions:    Kay: Hi Dr. Cabral, Thanks for your very informative and interesting podcasts. How would you advise a post-menopausal 60 y.o family member if they tested low in ferritin (39.4 ng/mL)? I've read that this biomarker shows how much energy your body's cells have and low levels would result in symptoms like fatigue, low energy/easily tired and excessive hair shedding. This family member suffers from these symptoms. Other biomarkers revealed low AM cortisol and low LDL-C/ApoB ratio (1.1) and low basal metabolic rate of 1143 kcals/day. Although her TSH tested normal (1.3 uIU/mL), she's been on levothyroxine 75 mcg to manage hypothyroid. Her high-sensitivity CRP was not optimal at 1.49 mg/L and she has a family history of heart disease. What would you recommend for this family member? Thanks      Earl: I am currently on 20 mg of lisinopril daily. Also, my GFR is 62. Would either of these be a concern when considering creatine?       Alesi: Dr.Cabral, can you please explain Alpha-gal syndrom? Why does it happen, how to confirm it by testing and how would you approach it? Is it treatable? Thank you      Peter: Hello, Dr.Cabral. I am an integrative health practitioner and would like to thank you for helping me understand the underlying causes of human imbalances. There is one thing that makes no sense to me though…regarding IgG testing, why would you recommend to test every year? Why doesn't suffice to test once and simply stay away from intolerant food items? Why would these intolerances change? Also, in my country there are IgG4 vs IgG1-3 testing options, what are the differences? Thank you very much for your time and knowledge you share with us.       Dipali: Hi I want to start 7 days detox plan, I already did your minerals and heavy metal test, I got my results back. My question is I am taking berberine, oregano oil and magnesium citrate,( I am prediabetic my Hba1c is 6.2)do I need to stop before starting detox method. Thanks       Thank you for tuning into today's Cabral HouseCall and be sure to check back tomorrow where we answer more of our community's questions!      - - - Show Notes and Resources: StephenCabral.com/3774 - - - Get a FREE Copy of Dr. Cabral's Book: The Rain Barrel Effect - - - Join the Community & Get Your Questions Answered: CabralSupportGroup.com - - - Dr. Cabral's Most Popular At-Home Lab Tests: > Complete Minerals & Metals Test (Test for mineral imbalances & heavy metal toxicity) - - - > Complete Candida, Metabolic & Vitamins Test (Test for 75 biomarkers including yeast & bacterial gut overgrowth, as well as vitamin levels) - - - > Complete Stress, Mood & Metabolism Test (Discover your complete thyroid, adrenal, hormone, vitamin D & insulin levels) - - - > Complete Food Sensitivity Test (Find out your hidden food sensitivities) - - - > Complete Omega-3 & Inflammation Test (Discover your levels of inflammation related to your omega-6 to omega-3 levels) - - - Get Your Question Answered On An Upcoming HouseCall: StephenCabral.com/askcabral - - - Would You Take 30 Seconds To Rate & Review The Cabral Concept? The best way to help me spread our mission of true natural health is to pass on the good word, and I read and appreciate every review!  

What if the key to a better sex life has nothing to do with sex itself? In this episode, I'm joined by my friend Jennifer Cohen to explore the powerful connection between wellness, confidence, fitness, and sexual health. We talk about overcoming performance anxiety, why exercise can improve desire and arousal, the role honesty plays in intimacy, and whether chemistry can actually grow over time. Plus, we answer audience questions about attraction, confidence, relationships, and the habits that help you feel your best both in and out of the bedroom. This episode is sponsored by Biologica: Head to https://biologica.com/SEXWITHEMILY to get started and get up to 32% off your first subscription order today! Take their Quick Hormonal Life Stage Quiz to find the formula that's right for you. ABOUT EMILY: Emily Morse is a Doctor of Human Sexuality, author and host of the #1 rated Sex with Emily podcast. Known as a renowned sexologist, Dr. Emily has helped millions of people around the world navigate their sex lives. Her candid and often funny conversations challenge cultural taboos, misinformation and awkward sex talks to create a future where people can deeply connect and embrace pleasure-filled lives. Because, life is too short for bad sex.  CONNECT WITH EMILY: Instagram: https://www.instagram.com/sexwithemily/  X: https://twitter.com/sexwithemily  Facebook: https://www.facebook.com/sexwithemily  TikTok: https://www.tiktok.com/@sexwithemily  Threads: https://www.threads.net/@sexwithemily CONNECT WITH JENNIFER COHEN: Instagram: https://www.instagram.com/therealjencohen/ TikTok: https://www.tiktok.com/@therealjencohen YouTube: https://www.youtube.com/@habitsandhustle Website: https://www.jennifercohen.com/  WANT MORE? Visit the Website: https://sexwithemily.com/ which includes FREE guides. Free Downloadable Guides: https://sexwithemily.com/guides/  Text With Me: https://sexwithemily.com/text  Receive Sex Tips On The Regular: https://sexwithemily.com/subscribe  Interested in 1:1 Coaching with Emily? Go to http://sexwithemily.com/coaching to apply!  Chapters: 00:00 Why Sexual Health Changes Everything 01:14 The Link Between Feeling Good & Having Better Sex 03:12 Are Sex And Intimacy Actually The Same Thing? 04:47 Why Performance Anxiety Happens In Bed 06:10 The Trick To Stop Overthinking During Sex 10:00 Why Working Out Makes Sex Better 12:03 How We Became Friends & Started Talking About Sex Nonstop 13:44 How To Tell Your Partner About Your Insecurities 16:08 How To Actually Approach Someone Without Being Weird 18:43 Masculine Energy, Feminine Energy & Dating Drama 24:42 Biohacking, Wellness & Feeling Hot Again 27:38 Vaginal Dryness, Hormones & Things Nobody Talks About 31:55 Aminos, Creatine & The Confidence Glow Up 34:00 Why Chemistry Matters more Than You Think Learn more about your ad choices. Visit megaphone.fm/adchoices

You have been told that weight gain, crippling anxiety, and hot flashes are just a "normal" part of getting older. But what if your menopausal symptoms are actually a warning sign that your gut and liver are failing to detoxify your body? And what if the unresolved trauma from your childhood is physically aging your ovaries right now? In this episode, nurse practitioner and bestselling author Cynthia Thurlow exposes the clinical realities of perimenopause and menopause. We break down the "Estrobolome"—the hidden collection of gut bacteria responsible for removing estrogen from your body—and explain why common constipation is causing toxic hormones to recirculate and drive estrogen dominance. Cynthia also reveals why millions of women are prescribed synthetic thyroid medications (like Synthroid) that their bodies literally cannot use, and outlines the exact nutritional and supplemental protocols (including Creatine, Magnesium, and Myo-inositol) required to truly repair your endocrine system. Uncover what's really going on in your body with advanced biomarker testing for hormones, thyroid, and metabolism— plus a 1-hour consultation with a Senior Health Advisor! → http://mybloodwork.com Thank you to our sponsors! Sunlighten Sauna: https://get.sunlighten.com/axepodcast Manukora Manuka Honey: https://manukora.com/axe Caraway Home: carawayhome.com/drjoshaxe (Use code DRJOSHAXE) for an exclusive discount Watch The Dr. Josh Axe Show every Monday & Thursday on YouTube: https://www.youtube.com/@drjoshaxe?sub_confirmation=1

Work With Me 1:1 Coaching - https://ericrobertsfitness.com/erf-1on1.html On today's episode I share a live recording I did on my TikTok where I took your questions on some of the topics I get asked about most — calorie deficits, whether calorie banking actually works, intermittent fasting, creatine for women, and whether you can actually ruin your metabolism. I also share a story I don't tell that often about the time lifting weights literally saved my life — and why that's the real reason I tell everyone to strength train no matter what. If you've ever talked yourself out of a workout because your nutrition wasn't perfect that day, this one's for you. Join my Clubhouse App - https://ericrobertsfitness.com/clubhouse-page.html Free Calorie Calculator https://ericrobertsfitness.com/free-calorie-calculator/ 20% Off Legion Athletic Supplements Code “ERIC” HERE https://legionathletics.rfrl.co/qj2dy Youtube Channel https://www.youtube.com/@ericrobertsfitness Video Podcast: https://www.youtube.com/@EricRobertsFitnessPodcast

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How CD38, PARP, and Leaky Gut Are Destroying Your NAD Levels | Dr. Andrew Salzman Your NAD is being drained by two hidden enzymes, your gut may be the starting point of every aging process in your body, and creatine does something to your mitochondria that has nothing to do with muscle. This episode rewrites what you thought you knew about longevity, anti-aging biology, and how your body actually produces and delivers energy at the cellular level. -Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR -Explore all of Wonderfeel's products at: getwonderfeel.com/dave They are gifting a complimentary 7-day Youngr™ supply (mini pouch) with every order across any of their products. The code will be DAVE, and the campaign will be active through June 6th. Host Dave Asprey sits down with Dr. Andrew Salzman, a physician, inventor, and biomedical entrepreneur with more than 30 years of experience in drug discovery and development. An alumnus of Harvard Medical School, Yale University, and Columbia University, Dr. Salzman has authored more than 170 scientific publications and holds 50 patents. He invented the original clinical-stage PARP-1 inhibitor, leading to the world's first clinical treatment for raising NAD levels and fighting cancers caused by the BRCA1 and BRCA2 genes. Genentech licensed his breakthrough technology for $600 million. His research into gastrointestinal microbiota, autoimmune disease, oxidative stress, and mitochondrial ATP production now forms the foundation of how millions of patients get treated worldwide. Dr. Salzman names the two biggest NAD drains in your body, CD38 and PARP, and explains why taking NMN or NR alone is like filling a bathtub with the drain wide open. He breaks down the formulation science behind pairing NAD precursors with CD38 blockers like hydroxytyrosol alongside PARP-reducing antioxidants like ergothioneine, and delivers a paradigm-shifting explanation of creatine as an energy distribution network inside your cells. Rather than a simple muscle supplement, creatine acts as a high-speed ATP shuttle that carries energy from your mitochondria to the precise location and moment your brain, gut, and heart need it most. You'll Learn: Why NAD declines with age and which two enzymes are primarily responsible for draining it How CD38 rises with inflammation rather than NAD levels, and what that means for your supplement strategy Why creatine is one of the most underrated anti-aging and brain optimization supplements available How creatine functions as a spatial and temporal energy delivery network for your brain, gut, and heart Why the gut may be the origin point of the entire aging process and how that cascade unfolds decade by decade How leaky gut drives systemic inflammation, crashes NAD, and accelerates biological aging throughout the body What controls tight junction integrity and how ATP, butyrate, creatine, and fasting all play a role Why most creatine supplements fail to absorb properly and what to look for in a high-quality source How to rebuild your microbiome in three to four weeks through diet alone, without antibiotics Why walking immediately after a meal may be doing more harm than good to your gut lining Thank you to our sponsors! - Screenfit | Get your at-home eye training program for 40% off using code DAVE at https://www.screenfit.com/dave. - KILLSwitch | If you're ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off - Pique | Go to Piquelife.com/dave for 20% off. - iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights inhealth, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. Keywords: Dr. Andrew Salzman, NAD depletion, CD38 inhibition, PARP inhibition, NMN supplements, creatine ATP shuttle, leaky gut aging, tight junction integrity, inflammaging, lipopolysaccharide gut, flagellin toxin, butyrate gut healing, ergothioneine, hydroxytyrosol, peroxynitrite, superoxide mitochondria, creatine energy distribution, gut origin of aging, NAD bathtub analogy, BRCA PARP inhibitor, Wonderfeel, creatine monohydrate, intestinal permeability, microbiome butyrate, selective digestive decontamination, TMAO nitric oxide Resources: • Explore all of Wonderfeel's products at: getwonderfeel.com/dave • Order Youngr™: getwonderfeel.com/dave• Order ChocoCreatin™: getwonderfeel.com/dave• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ • Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today. • Danger Coffee: https://dangercoffee.com/discount/dave15 • My Daily Supplements: SuppGrade Labs (15% Off) • Favorite Blue Light Blocking Glasses: TrueDark (15% Off) • Dave Asprey's BEYOND Conference: https://beyondconference.com • Dave Asprey's New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated • Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ • Upgrade Labs: https://upgradelabs.com Timestamps: 00:00 – Trailer 01:12 – Introduction & BRCA Background 02:19 – DNA Damage & PARP 04:38 – Free Radicals & Oxidative Stress 11:37 – NAD & Antioxidant Defense 12:34 – CD38 & NAD Depletion 23:31 – The Gut-Aging Hypothesis 30:05 – ATP, Creatine & Energy Distribution 36:41 – Creatine as Energy Shuttle 51:09 – Microbiome & Gut Repair 59:21 – TMAO & Nitric Oxide Interference 1:03:52 – Flagellin & Gut Inflammation Research 1:09:45 – FDA & Pharmaceutical Incentives 1:16:05 – Closing See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.