Podcasts about prp

The Post Relevant Podcast is a secret brought to Earth through the wise Owl, handed off to a cadre of Hawks, red-eyed demon dogs, an army of Deer, an Air Force of Vultures, and borne to the foot of the the mystical Blue Heron, who blesses every episode and eventually drops them beneath the Blue Moon into the ears of local Rabbits. The Rabbits leave each episodes of the show on listener's doorsteps, wrapped inside an acorn shell encased in flower petals. Its a cottage industry, but very efficient!Twin Peaks: the Return: the DECODE returns with an interpretation of episode 9! Its a 'no-bells-and-whistles' soft reboot of our show, originally recorded in January 2025 at the beginning of the LA fires. Appropriate for a Twin Peaks podcast, and strangely synchronous for our current "Year of the Fire Horse" in 2026. Hosts Phil Ristaino and Justin Epifanio recount Justin's first-hand experience surviving the Los Angeles inferno. Then they go in deep into trying to explain TP:TR episode 9. Statements are made, like "Its a fucking morgue!" And they are not wrong. Cutting questions are posed, like "When did he lose his marbles?" Insights are given, like "When the dog got his cat's eyes?" Tammy poses. Chad huffs and puffs. William Hastings yearns for scuba diving and mixed drinks. All the while, the disembodied head and decapitated body of Major Briggs looms large, holds clues, and rings like a monastery bell. We discover much!Throughout the show, Phil recounts stories of being visited by different wild animals while exploring the city of Nashville TN. Its another trippy show! Hope you enjoy it - I didn't mean for it to be over 3 hours, but, well, there you go....Find all episodes of the PRP:  https://www.postrelevant.comPhil's acting/art/music: https://www.thesearedreams.comPRP on Insta: https://www.instagram.com/philristaino/Get the PRP "Under the Silver Lake" tribute shirt at Spyrodon Apparel:https://spyrodon.store/products/phil-ristaino-artist-edition-for-the-post-relevant-podcast-under-the-silverlakeenter 'postrelevant' at checkout for 10% off.Donate to the show: https://buymeacoffee.com/postrelevantand https://patreon.com/postrelevantJustin's doc: https://www.instagram.com/heyoka.documentary/PRP theme song by Agents of Venus: https://agentsofvenus.bandcamp.comDavid Lynch Forever....

It’s ICECO Month, and they brought in the right guy for it. David from ICECO says that after COVID changed everything. Like a lot of people, he went outside, went wheeling, and ended up pivoting his whole career around it. Now he’s working with a brand that started in OEM refrigeration — manufacturing the internals that go inside other companies’ products — before expanding into the outdoor and overlanding space. That OEM history matters because it’s where the technology comes from. ICECO runs SECOP compressors, which articulate up to 40 degrees without throwing an error — something Jimmy can personally relate to after loading a competitor’s fridge into his truck and watching it fault out. The conversation goes well past compressor specs. David and Tyler get into the framing that stuck with Jimmy most by the end: a fridge isn’t a recreational product that you also use at home — it’s a lifestyle tool that you bring with you. Jimmy’s been using a small fridge for grocery runs with his wife. She loads the car fridge first, doesn’t have to make the store her last stop, and comes home when she feels like it. That’s not overlanding. That’s just Tuesday. And it opened up a whole line of thinking about how the technology is circling back to everyday life after coming through the outdoor market. From there the episode covers some of the new product stuff: the refrigerated backpack (cold drinks on a day hike — the gap between “car camp” and “pack everything in”), the VL45 Plus front-opening drawer fridge that launched on Kickstarter June 10th (Tyler’s take: this solves the “I have to keep the whole back seat clear to open the lid” problem), and the ICECO x PRP collab coolers. David also teases some upcoming product lines he can’t fully get into — racing cooling systems among them, including what sounds like a wearable air conditioning system for fire suits. Tyler’s response: he wants a refrigerator fanny pack for one beer. ICECOWebsite: https://icecofreezer.com/Instagram: https://www.instagram.com/icecofreezer/?hl=enKickstarter: https://www.kickstarter.com/projects/iceco/iceco-vl45-plus-the-first-3-way-access-portable-freezer SnailTrail4x4 Discord: https://discord.gg/yFyFFkQbuyCome hang out with us on the SnailTrail4x4 Discord — it’s the easiest way to connect with Tyler and Jimmy directly, chat with fellow offroad enthusiasts, and get first access to Group Buys and Treasure Hunt token drops. MORRFlate Giveaway at 900 Reviews on Apple Podcast. But our next giveaway is when we reach 800 reviews; we are giving away an OnX Elite Membership. We will also give away an OnX Elite membership when we get to 850. However, when we reach 900 Reviews, we are teaming up with MORRFlate for a $1000 MF Product Giveaway. Go over to Apple Podcasts to leave your review now and become eligible to win. Congratulations to A13XMONT, who won a set of tires from Yokohama Tire! Call us and leave us a VOICEMAIL!!! We want to hear from you even more!!! You can call and say whatever you like! Ask a question, leave feedback, correct some information about welding, say how much you hate your Jeep, and wish you had a Toyota! We will air them all, live, on the podcast! +01-916-345-4744. If you have any negative feedback, you can call our negative feedback hotline, 408-800-5169. 4Wheel Underground has all the suspension parts you need to take your off-road rig from leaf springs to a performance suspension system. We just ordered our kits for Kermit and Samantha and are looking forward to getting them. The ordering process was quite simple, and after answering the questionnaire, we ensured we got the correct and best-fitting kits for our vehicles. If you want to level up your suspension game, check out 4Wheel Underground. SnailTrail4x4 Podcast is brought to you by all of our peeps over at irate4x4! Make sure to stop by and see all of the great perks you get for supporting SnailTrail4x4! Discount Codes, Monthly Give-Always, Gift Boxes, the SnailTrail4x4 Community, and the ST4x4 Treasure Hunt! Thank you to all of those who support us! We couldn’t do it without you guys (and gals!)! SnailSquad Monthly Giveaway This month’s giveaway is with Iceco Freezers. We are excited to work with and share their exciting new releases. One lucky winner has a chance to an ALP20 Fridge. Big thanks to Iceco for sponsoring this month’s giveaway. If you want a chance to win, sign up for the Giveaway Tier on Irate4x4 Congrats to Johnny Freskie, you won the Rusoh Fire Extinguishers. We have one of their 2.5-pound extinguishers to give away to a lucky winner. This extinguisher has an 18-year shelf life and is the best fire extinguisher for any off-road vehicle. To learn more, check out Rusoh.com. If you want a chance to win, sign up for the Giveaway Tier on Irate4x4 Listener Discount Codes: SnailTrail4x4 –SnailTrail15 for 15% off SnailTrail4x4 MerchMORRFlate – snailtraill4x4 to get 10% off MORRFlate Multi Tire Inflation Deflation™ Kits4WheelUnderground – snailtrail 10% offIronman 4×4 – snailtrail20 to get 20% off all Ironman 4×4 branded equipment!Sidetracked Offroad – snailtrail4x4 (lowercase) to get 15% off lights and recovery gearSpartan Rope – snailtrail4x4 to get 10% off sitewideShock Surplus – SNAILTRAIL4x4 to get $25 off any order!Mob Armor – SNAILTRAIL4X4 for 15% offSummerShine Supply – ST4x4 for 10% offBackpacker’s Pantry – Affiliate LinkLaminx Protective Films – Use the Link to get 20% off all products (Affiliate Link) Show Music: Midroll Music – ComaStudio Outroll Music – Meizong Kumbang

What if the key to healing chronic pain, inflammation, and degenerative conditions lies in supporting the body's natural ability to regenerate? In this episode of Light Body Radio, Dr. Lara May is joined by regenerative medicine experts Mick Emandi and Greg Carder for a fascinating conversation about the science and future of regenerative health. Together, they explore how oxidative stress and chronic inflammation contribute to many of today's most common health challenges and discuss emerging therapies designed to address these issues at their source. Mick shares his experience helping thousands of patients through innovative regenerative approaches, while Greg breaks down the evolution of regenerative medicine, including platelet-rich plasma (PRP), stem cell therapies, placental-derived technologies, and the latest advancements in cellular signaling. Whether you're interested in chronic pain relief, longevity, functional medicine, or cutting-edge wellness innovations, this episode offers an insightful look into the body's remarkable capacity for healing and regeneration. © Light Body Radio-Podcast, 2026. All rights reserved. This podcast features background music by ScottHolmes Music. We have obtained the necessary licenses for the use of this music. Our license was renewed on May 7, 2024, and we have been using ScottHolmes Music since 2017. Unauthorized use or distribution of this podcast, including but not limited to the background music, is strictly prohibited and may result in legal action. For more information or to request permissions, please contact scott@scottholmesmusic.com.

In this episode, I'm joined by Dr. Maribelle Verdiales, a pioneer in regenerative and integrative fertility medicine. We dive into groundbreaking therapies like intraovarian stem cell infusions, exosomes, and ovarian PRP, and how they can support fertility, especially for women over 40. Dr. Verdiales shares her personal journey from being a traditional OB/GYN to becoming a holistic healer, and she explains the science, safety, and logistics behind these emerging treatments. We also talk about the inspiration behind her work, what's possible in fertility care today, and why she's so passionate about empowering women to take charge of their reproductive health. In this episode, we cover: What stem cells, exosomes, and PRP are, and how they might support fertility Why some regenerative treatments are offered in Mexico and what patients should know Real-life stories of hope from Dr. Verdiales' patients How regenerative therapies are helping women over 40 reclaim fertility What's next in the future of holistic and regenerative fertility care Resources Read the full show notes on my website, including a transcript. Dr. Maribelle Verdiales website, and her book, The Healing Circle: A Story of Health, Science, and Love Do you have questions about IVF, and what to expect? Click here to join Dr. Aimee for The IVF Class. The next live class call is on Monday, June 15, 2026 at 4pm PST, where Dr. Aimee will explain IVF and there will be time to ask her your questions live on Zoom. Dr. Aimee Eyvazzadeh is one of America's most well known fertility doctors. Her success rate at baby-making is what gives future parents hope when all hope is lost. She pioneered the TUSHY Method and BALLS Method to decrease your time to pregnancy. Learn more about the TUSHY Method and find a wealth of fertility resources at www.draimee.org. Other ways to connect: Subscribe to my YouTube channel for more fertility tips Join Egg Whisperer School Subscribe to the newsletter to get updates

Regenerative medicine is not just about treating pain, it is about helping the body remember how to heal. In this episode, Dr. Jen speaks with Dr. Ann Auburn about osteopathic manipulative medicine, craniosacral therapy, prolotherapy, PRP, and natural aesthetic treatments that support healing from the inside out. They discuss how structural imbalances can create chronic pain, why ligaments and fascia matter, how regenerative injections stimulate repair, and how PRP can be used for skin rejuvenation without synthetic fillers. This conversation offers a practical look at natural tools for pain, movement, aging, and whole-body resilience. Dr. Ann Auburn, DO, is a board-certified osteopathic physician and founder of the Natural Health Improvement Center in West Michigan. With more than three decades of clinical experience, she specializes in osteopathic manipulative medicine, craniosacral therapy, prolotherapy, PRP, and integrative approaches to chronic pain and healing. Through her clinical work, teaching, and leadership, Dr. Auburn helps patients restore function, reduce pain, and support the body's innate ability to heal naturally. Website: https://www.nhicwestmi.com Instagram: https://www.instagram.com/nhicwestmi Facebook: https://www.facebook.com/NHIC.Michigan  YouTube: https://www.youtube.com/@nhicwestmi  PODCAST: Thank you for listening please subscribe and share! Shop supplements: https://healthybydrjen.shop/CHECK OUT a list of my Favorite products here: https://www.healthybydrjen.com/drjenfavoritesFOLLOW ME:Instagram: https://www.instagram.com/integrativedrmom/Facebook:  https://www.facebook.com/integrativedrmomYouTube: https://www.youtube.com/@integrativedrmomFTC: Some links included in this description might be affiliate links. If you purchase a product through one of them, I will receive a commission (at no additional cost to you).  I truly appreciate your support of my channel. Thank you for watching! Video is not sponsored.DISCLAIMER: This podcast does not contain any medical or health related diagnosis or treatment advice. Content provided on this podcast is for informational purposes only.  For any medical or health related advice, please consult with a physician or other healthcare professionals. Further, information about specific products or treatments within this podcast are not to diagnose, treat, cure or prevent disease.

In this episode, we delve into the advances, myths, and realities of knee and joint replacement with Dr. David William Fabi, a board-certified, fellowship-trained joint replacement specialist and internationally recognized pioneer in the field. Darleen, the host,  engages Dr. Fabi in a dynamic conversation about why the frequency of knee replacements is increasing, the influence of the baby boomer generation on current trends, and why more people are opting for surgery at younger ages. Listeners will uncover the intricacies of elective joint replacement—why “need” isn't always the right word, the value of conservative management, and the sometimes murky results around popular treatments like PRP and stem cell therapies.Dr. Fabi sheds light on major advances in surgical approaches, including smaller incisions, improved implant design, and the integration of robotics and computer technology, which have significantly improved outcomes, shortened recovery times, and reduced dissatisfaction rates. He shares invaluable tips for patients: from what questions to ask surgeons about technology and technique, to the importance of mental health and motivation in post-surgical recovery. We also tackle the nuances of online research, patient-doctor trust, and the evolving landscape of telemedicine and AI in orthopedic care.The episode wraps up with a forward-looking discussion on the future of joint replacement—touching on artificial intelligence, augmented reality, and even 3D printing—as well as advice for those considering surgery to prioritize quality of life, seek second opinions, and connect with relatable, authentic care providers.If you—or someone you love—is considering a knee replacement or just curious about how technology is reshaping the field of orthopedics, this episode offers must-hear insights and takeaways from a leading expert.San Diego Orthopedic Institute. Our phone number is 619-299-8500 https://www.sandiegohipandkneedoc.com/https://discsurgerycenter.com/physician/david-william-fabi-md/SeniorLivingGuide.com Podcast sponsored by LivDry Incontinence Products & TerraBella Senior Living The background music is written, performed and produced exclusively by purple-planet.com.https://www.purple-planet.com/*SeniorLivingGuide.com Webinars and Podcast represents the opinions and expertise of our guests. The content here is for informational and educational purposes. It does not necessarily represent the views, recommendations, opinions or advice of Fairfax Publishing/SeniorLivingGuide.com or its employees

Episode 351 hosts Sara Lavis (Registered Nurse from Perth, Australia) In this episode we discuss how to best integrate skin treatments and devices into your aesthetic clinic or medispa - with a focus on NanoFractional RF technology by Venus. Our conversation highlights some of the key tools to patient conversion when it comes to skin treatments - including a systematic consultation and having tools to examine skin quality objectively. Sara outlines the modalities she uses in her clinic and explains how and why she chose these devices. She then shares her insights about NanoFractional Radiofrequency using the Venus Versa Pro platform. We discuss the indications for it, ideal patient selection, the procedure and expectations. We also cover the concept of 'stacking' treatments with RF including polynucleotides, exosomes, PRP and insulin. 00:00 Introduction 01:39 Meet our Special Guest: Sara Lavis 05:42 Holistic Skin Shift 07:00 Learning Skin Confidence 09:46 Clinic Team And Workflow 10:49 Skin Assessment Tools 12:46 Non Pushy Skin Conversations 15:46 Devices In The Clinic 17:16 Choosing The Right Device 19:36 RF Basics And Candidates 23:32 Venus Versa Heads Explained 25:34 Multimodality Business Logic 28:16 RF Treatment Journey 31:03 Surface RF Explained 31:25 Ablation Vs Coagulation 32:13 RF Vs CO2 Downtime 33:03 Stacking Polynucleotides 34:16 All Skin Types Safety 35:02 Under Eye Skin Prep 36:06 PRP Exosomes And Insulin 38:02 Pores Texture And Resurfacing 39:06 Pigment Protocols And Melasma 41:44 Overtreatment Scope And Referrals 44:24 Consumables Pricing And Timing 47:34 Vendor Support And Upgrades 50:35 Clinic Future And Acne Bridge 53:30 Why Stacking Works 55:55 Wrap Up DOWNLOAD OUR NEW APP IA COMMUNITY: DOWNLOAD FOR APPLE DEVICES DOWNLOAD FOR ANDROID DEVICES THEN GET A FREE 30 DAY SUBSCRIPTION (After you've downloaded the app and signed up for free): FOR HEALTHCARE PROFESSIONALS FOR BUSINESS OWNERS/NON-CLINICAL PROFESSIONALS

In this episode of the Ageless Future Podcast, orthopedic surgeon and regenerative medicine specialist Dr. Marc Pietropaoli shares his journey from traditional orthopedic surgery to a more restorative approach focused on preserving joints whenever possible. He discusses how personal experiences and decades of clinical practice inspired his “Repair, Not Replace” philosophy, emphasizing minimally invasive care, personalized treatment plans, rehabilitation, and lifestyle support. The conversation explores the growing interest in regenerative medicine, advancements in sports injury recovery, and the importance of patient education, long-term data tracking, and prevention-focused care. Dr. Pietropaoli also outlines his broader vision for the future of orthopedic treatment and how emerging technologies may reshape musculoskeletal health in the years ahead.Dr. Marc Pietropaoli is an orthopedic surgeon, regenerative medicine specialist, international speaker, and #1 Amazon Best Selling Author of Repair NOT Replace™. He is the Founder and CEO of Victory In Motion, Home of Knee Repair, NOT Knee Replacement®, where he has spent decades challenging the traditional “replace it” model of orthopedic care.After completing his fellowship with Dr. James Andrews, one of the most respected sports medicine surgeons in the world, Dr. Pietropaoli began questioning why damaged joints were routinely replaced rather than repaired. That question became his life's work.Today, he leads a non-insurance-based, outcomes-driven practice focused on identifying the true root cause of joint pain through a comprehensive diagnostic process. His approach integrates bone marrow aspirate cells, PRP, laser therapy, genetic-based nutrition, and V-Motion Fit, a personalized total body fitness, strength and conditioning program.Dr. Pietropaoli is on a mission to eliminate the need for knee replacements by 2043, challenging both patients and the medical community to rethink what is possible when it comes to joint health, performance, and longevity.RESOURCES:Book Comprehensive Labs: https://agelessfuture.com/longevity-labs/FREE copy of The Peptide Blueprint: https://agelessfuture.com/blueprintSign up for future Health Accelerator Challenges calls LIVE! https://us02web.zoom.us/webinar/register/WN_YZsiUMOzSyqcE8IinC5YEQ#/registrationBooks: https://www.amazon.com/Books-Regan-Archibald/s?rh=n%3A283155%2Cp_27%3ARegan%2BArchibaldArticles: https://medium.com/search?q=Regan+ArchibaldLIKE/FOLLOW/SUBSCRIBE:YouTube -https://www.youtube.com/@ReganArchibald / https://www.youtube.com/@Ageless.FutureLinkedIn: https://www.linkedin.com/in/regan-archibald-ab70b813Instagram: https://www.instagram.com/ageless.future/Facebook: https://www.facebook.com/AgelessFutureHealth/DISCLAIMER: This video is for educational purposes only and does not provide medical advice, diagnosis, or treatment.  Many of the molecules discussed in this video are research compounds and are not approved by the U.S. Food and Drug Administration (FDA) for any specific medical use, indication, or condition. They are mentioned only in the context of existing scientific literature and ongoing research and are not being recommended, prescribed, sold, or offered through this video.  This content does not endorse or recommend any specific tests, products, procedures, or treatment protocols.References to our clinic are for general educational context only; investigational or non‑approved products are not available for direct ordering or prescribing based solely on viewing this content.  Do not start, stop, or change any medication, peptide, or supplement based on this video. All medical decisions must be made with a licensed prescribing clinician after a proper evaluation. No provider–patient relationship is created by viewing this content or contacting our clinic.  Regan Archibald is a Licensed Acupuncturist and longevity coach. He is not a medical doctor. Cade Archibald is COO and Co-Founder of Ageless Future, also not a medical doctor. All medical decisions, lab ordering, and prescribing in our clinic are performed only by our licensed medical team (MD, APRN, PA).  Viewers should follow the guidance of their own licensed clinicians and local health authorities regarding diagnosis and treatment decisions.

Today, I'm joined by Dr. William Davis, a cardiologist-turned-gut detective and bestselling author behind Wheat Belly, Super Gut, and Super Body. In this episode, Dr. Davis breaks down what it really means to have youthful, functional muscle, why maintaining the muscle of your 20s and 30s is about so much more than hitting the gym, and how missing microbes—like L. reuteri—might be the secret to restoring your strength and energy. Previous Episodes:  #330: Lose the Bloat, Fix Your GUT: Inside the Microbiome Revolution (Skin, Weight & Longevity Secrets) with Dr William Davis Episode Timestamps: Welcome, host and episode introduction ... 00:00:00 What is youthful, functional muscle? ... 00:04:40 Antibiotics, gut microbes, and aging ... 00:07:14 Microbiome's link to inflammation and mood ... 00:09:31 How gut dysfunction drives disease ... 00:11:07 Conventional medicine's blind spot and SIBO ... 00:15:26 Testing for SIBO and its prevalence ... 00:21:49 “Microbe-driven” muscle & SIBO yogurt fermentation ... 00:24:17 Why fermented foods and keystone microbes matter ... 00:28:11 GLP-1 obesity drugs: risks and rebound ... 00:31:17 Extreme dieting and lasting metabolic effects ... 00:37:04 From cardiology to gut health: Dr. Davis's journey ... 00:40:30 DIY approaches for restoring health ... 00:45:05 Modern diet pitfalls vs. ancestral eating ... 00:46:42 L. reuteri, oxytocin, and muscle growth ... 00:53:00 How to start and troubleshoot SIBO yogurt ... 01:01:39 Practical 30-day protocol for vitality ... 01:09:22 Episode wrap-up and thanks ... 01:18:42 Our Amazing Sponsors: Vampire Exosome by Young Goose - A next-generation serum packed with three trillion PRP-derived exosomes and RejuvNAD to support collagen production and skin renewal at the cellular level—helping results build over time instead of fading fast. CLICK HERE and use code NAT10. Apollo Neuro — A wearable nervous system support device that uses personalized SmartVibes technology to help you feel calmer, more focused, and better able to shift into rest mode without adding another complicated wellness routine. Head to apolloneuro.com/nat and use code NAT for $99 off and 1 year Smart Vibes Ai. MitoPure Gummies by Timeline: These clinically researched gummies support mitophagy to help renew your mitochondria and boost cellular energy, giving you a stronger biological foundation for resilience—visit timeline.com/nat20 to get 20% off. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

What if the "final frontier" of fertility care is not IVF technology, but the aging ovary itself? Can science help improve egg quality, mitochondrial function, and reproductive lifespan? And how do patients sort through what is proven, what is promising, and what is still very much in the "ask your doctor before you try this" category? In this episode of Brave & Curious, Dr. Lora Shahine welcomes reproductive endocrinologist Dr. Roohi Jeelani for a fascinating conversation about ovarian rejuvenation, age-related fertility decline, and the future of fertility treatment.  Together, they discuss why age remains one of the biggest factors in IVF success, how egg quality changes over time, and why topics like oxidative stress, mitochondrial health, inflammation, and lifestyle optimization are becoming such important parts of the fertility conversation. In this episode you'll hear: [1:07] Meet Dr. Roohi Jeelani [2:32] Age and fertility [4:23] Egg quality basics [8:06] Sleep and fertility [9:35] Stress and cortisol [14:58] Movement and PCOS [16:54] Nutrition for fertility [18:51] Trimester zero prep: Small, sustainable changes [29:25] CoQ10, Inositol, Melatonin [35:38] NAD and egg quality [43:56] GLP-1 fertility questions [47:22] Peptides and PRP [55:33] Ovarian rejuvenation research [1:01:04] Future fertility medicine Resources mentioned:  onto.health @roohijeelanimd on Instagram | LinkedIn @onto-health-co on LinkedIn Your Leggings Could be Causing Infertility? with Dr. Lora Shahine on YouTube Can CoQ10 Improve Egg Quality and Sperm Health for TTC? with Dr. Lora Shahine on YouTube Does Growth Hormone Improve IVF Outcomes? with Dr. Lora Shahine on YouTube Dr. Shahine's Weekly Newsletter on Fertility News and Recommendations Follow @drlorashahine Instagram | YouTube | Tiktok | Her Books Join the Learn at Pinnacle app to earn FREE CE Credit for listening to this episode! This episode was produced by Audiotocracy Podcast Production.  

In this episode of Mind Your Own Karma – Beyond theBandage, I sit down with Dr. Fawad Mian, a board-certifiedneurologist, regenerative medicine specialist, and founder of Vitality Integrative Wellness, to challenge one of the most common narratives around aging and pain—that chronic pain after 50 is inevitable and must be managed with medications or surgery. After experiencing multiple injuries himself and being toldthose were his only options, Dr. Mian chose a different path. Through regenerative therapies like PRP and stem cells, combined with detailed diagnostics and a unique approach to re-movement, he healed his own body—and built a practice centered on helping others do the same. This conversation is for anyone who feels dismissed, rushed,or stuck in the cycle of symptom management. We talk about why pain becomes chronic, what's often missed in traditional care, and how the body's capacity to heal doesn't simply disappear with age.What you'll learn in this episode:Why chronic pain is not “just part of getting older”How regenerative medicine works at the tissue and nervous system levelWhat PRP and stem cell therapies actually do inside the bodyHow Dr. Mian evaluates the root cause of pain, not just where it hurtsWhat re-movement is and why exercise alone often isn't enoughHow to know if regenerative medicine may be right for youThe questions to ask so you can make informed, confident decisionsWhy hope and healing are still possible well beyond 50Where to find Dr. Fawad Mian:Website: https://prolohealing.com/Website: https://www.advocareneurowellnessmd.com/YouTube: https://www.youtube.com/@prolohealingLinkedIn: https://www.linkedin.com/in/fawad-mian-40aaaa150/Instagram: https://www.instagram.com/prolohealingmedspa/Book: Getting to Pain Free: How to Make Your Body Stop Hurting So You Can Start Living Without Drugs or Surgeryhttps://www.amazon.com/dp/B0D46W27T5FIND MELISSAON WEBSITES:⁠https://www.somatichealingjourneys.com⁠⁠https://www.mindyourownkarma.com⁠ON SOCIALSMYOK on Instagram:⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.instagram.com/mind_your_own_karma⁠⁠⁠⁠⁠⁠⁠⁠⁠MYOK on Facebook:⁠⁠⁠⁠⁠⁠⁠⁠⁠https://www.facebook.com/mindyourownkarma⁠⁠⁠⁠⁠⁠⁠⁠MYOK on YouTube:⁠⁠⁠⁠⁠⁠https://www.youtube.com/@MindYourOwnKarma⁠⁠This episode is for educational purposes only and is notintended as medical advice.#MindYourOwnKarma #SomaticMindfulGuidedImagery #SMGI #SomaticHealingJourneys #RegenerativeMedicine #ChronicPainRecovery #StemCellTherapy #PRPTherapy #NeurologyMeetsHealing #HealingWithoutMeds #MovementReeducation #PainFreeLiving #Over50AndThriving#AlternativeHealingModalities #RootCauseHealing #HighPerformanceHealing #HolisticNeurology #DrFawadMian #MindBodyMedicine #PainIsNotYourNormal #ChronicPain

Treating erectile dysfunction is not as simple as taking a pill and hoping for the best.In this episode, you'll get an inside look at the full ED evaluation process and learn why finding the root cause of ED is the key to restoring your sexual performance. Also, discover the advanced ED treatment options designed to improve natural function instead of relying only on medication. If you want to better understand erectile dysfunction and learn what may actually be preventing stronger, lasting erections, this is an episode you won't want to miss.Press play and tune in to the full podcast episode now.--------------Key TakeawaysErectile dysfunction can signal deeper health issues.Blood flow problems are a common cause of ED.Testosterone levels affect sexual performance.Stress and anxiety can worsen erectile dysfunction.Comprehensive blood work helps identify root causes.Shockwave therapy may improve penile blood flow.PRP therapy supports natural tissue healing.Pelvic floor strength impacts erection quality.Lifestyle changes help improve long-term ED recovery.Personalized ED treatment works better than quick fixes.--------------Resources mentioned:Modern Man CribMediterranean DietGood Morning Wood SmoothieRenew with Dr. Anne--------------Curious about how you can boost your bedroom game and build lasting confidence? Check out the course at getwoodnow.com and start your journey to feeling like yourself again!--------------If you enjoyed this episode and want to learn more and get more tips, subscribe to The Modern Man newsletter for exclusive content delivered straight to your inbox! https://dranne.co/themodernman--------------Follow Me On:InstagramTwitterFacebookTikTokYouTube--------------For all links and resources mentioned on the show and where to subscribe to the podcast, please visit https://truongrehab.com/erectile-dysfunction-evaluation-treatment-guide--------------Want to regain control of your sex life? It's time to reverse the effects of ED on your life. Join the Modern Man Club and embark on your journey to complete recovery and community.--------------Reveal the FREE treatment most men ignore that solves thousands of erectile dysfunction cases every year, plus the 5 biggest mistakes you must avoid if you want to say goodbye to your ED. Uncover it all in my free eBook, available to download now.https://dranne.co/ebook

What happens when the options you're given don't feel like the right fit? In this episode of the Starter Girlz Podcast, Jennifer Loehding sits down with neurologist and regenerative medicine specialist Dr. Fawad Mian for a conversation about pain, healing, and the power of asking better questions. After facing his own injuries and being told surgery was the answer, Dr. Mian began searching for another way. That personal experience changed the way he approached medicine and led him into regenerative and functional treatments designed to help people restore movement, rebuild confidence, and reclaim their lives. This conversation explores chronic pain, PRP, prolotherapy, functional medicine, inflammation, aging well, and why sometimes the path forward begins by looking beyond the first answer you were given. Chapters00:00 Only Option Is Surgery01:22 Meet Dr Fawad Mian02:14 Host Injury Story03:16 Why He Practices Differently03:57 Shoulder Injury Wakeup Call04:54 Foot Pain And Achilles Spiral06:16 Knee Surgery And No Answers08:02 Discovering PRP Prolotherapy09:25 Podcast Community Break10:07 Host Trigeminal Journey11:58 Functional Medicine And Ozone14:52 Root Cause Healing Mindset18:03 Where To Start With Pain22:30 Why He Chose Medicine25:40 Aging Well Strength Sleep Diet33:36 Book New Treatments And Research36:09 Pushback And Memory Course40:24 Where To Find Dr Mian42:01 Final Takeaways And Goodbye About Dr. Fawad MianDr. Fawad Mian is a neurologist and regenerative medicine specialist who helps active adults overcome chronic pain without relying solely on surgery or long-term medication. His work blends traditional medical knowledge with regenerative and functional approaches, including PRP, prolotherapy, stem cell therapy, movement re-education, and other treatments designed to support healing at the root. Connect with Dr. Fawad MianWebsite: https://prolohealing.comMemory Course: https://course.prolohealing.com/webinar-registrationEmail: ask@prolohealing.com Connect with Starter Girlzhttps://startergirlz.comTake the 2-Minute Success Block Quiz to discover what may be holding you back. Want to Be a Guest on Starter Girlz Podcasthttps://www.podmatch.com/hostdetailpreview/17044863446695017c1879d7b

Twenty-five years of being dismissed, misdiagnosed, and told it was all in her head. By the time Elena Herning finally got answers, she had lost her home, her belongings, her ability to drive, and very nearly her life. In this episode of Integrative Cancer Solutions, Dr. K sits down with Elena Herning, patient advocate and TruDOSE™ ambassador, to trace her harrowing journey through undiagnosed Lyme disease, co-infections, toxic mold exposure, mast cell activation syndrome, POTS, MOG antibody disease, and COVID - and the single therapy that finally turned it all around. Elena breaks down what dose-specific IV platelet-rich plasma (TruDOSE™) actually does inside the body, why it crosses the blood-brain barrier, how it unwinds inflammatory loops that conventional medicine never addresses, and what it felt like to go from writing goodbye letters to her children to logging mile six on a treadmill. If you or someone you love is caught in the chronic illness spiral with no answers and no end in sight, this episode is for you. Key Takeaways: 0:00 Introduction  1:52 Undiagnosed for 25 years and what that looked like day to day  3:29 How a hysterectomy became the breaking point that revealed Lyme  9:04 Why Lyme is rarely the only problem  27:00 After energy healers, ozone, and a near liver transplant 29:38 What TruDOSE™ IV PRP is and how it differs from standard PRP  32:11 First treatment results and how fast things shifted  37:17 How dose-specific platelets cross the blood-brain barrier  Schedule a Free 15-Min Cancer/Lyme Consultation at The Karlfeldt Center: 208-338-8902 Resources: TruDOSE™ — https://trudose.com Medical Disclaimer: This content is for educational purposes only and is not intended to diagnose, treat, cure, or replace professional medical advice. Always consult your physician or qualified healthcare provider regarding any medical condition or treatment decisions. ____________________________________WORK WITH DR. KARLFELDT:The Karlfeldt Center offers the most cutting-edge and comprehensive Lyme therapies available. To schedule a Free 15-Minute Discovery Call with a Lyme Literate Naturopathic Doctor, contact us at:

Today, I'm joined by Kyal Van Der Leest, an innovative naturopath, nutritionist, and founder of LVLUP Health, whose formulas are changing the way we think about effective supplementation. Kyal's journey is deeply personal: from caring for his mother through a long battle with cancer, to overcoming his own intense health struggles with mold illness. These experiences led him to push past superficial fixes and dig deep into what really works for healing and optimizing the body. Visit www.lvluphealth.com and use code NAT for 20% off Previous Episodes:  Episode #116: Does the Perfect Gut Supplement Exist? Episode #148: Kyal Van Der Leest: Liver Health, Gut Health, and Detoxification #326: From Brain Fog to Focus: Techniques and Supplements to Enhance Cognitive Function With Kyal Van Der Leest Episode Timestamps: Welcome & Podcast intro ... 00:00:00 Pitfalls of cheap supplements & importance of quality ... 00:05:33 Mistakes: symptom chasing, green allopathy, and root causes ... 00:07:38 Blending naturopathy, biochemistry, and biohacking ... 00:10:26 Choosing peptides, herbs, or vitamins for target outcomes ... 00:16:43 Synergy, proprietary blends, and dosing transparency ... 00:18:06 Understanding supplement forms, dosages, and stack simplification ... 00:24:29 Root cause thinking: brain fog, labs, and interconnected symptoms ... 00:34:16 Dopamine, focus, and the risks of overstimulation ... 00:39:59 Peptides in brain health—a step beyond herbs or nutrients ... 00:43:00 Short-term nootropics vs. long-term investments in brain health ... 00:46:17 Longevity levers: muscle, blood sugar, and blood flow ... 00:51:04 Blood sugar regulation—berberine, dihydroberine, and alternatives ... 00:53:32 Liver's core role in hormones and energy ... 00:55:59 Heart and lung health—peptides, circulation, and overlooked systems ... 01:00:10 Peptides vs. herbs—when to choose and when to avoid ... 01:04:21 Future of peptides, supplement quality, and industry direction ... 01:07:45 Hierarchy: Foundations before biohacks ... 01:08:57 Simple, high-impact upgrade picks & final advice ... 01:11:17 Industry trends, influencer issues, and episode wrap ... 01:17:01 Where to find Kyal and promo code details ... 01:19:19 Our Amazing Sponsors: Sunlighten: Up to $2,100 off + FREE shipping Sunlighten Sauna - Looking to support your recovery and calm your nervous system? Sunlighten offers full spectrum infrared saunas—compact enough for real homes, powerful enough to support detoxification, mitochondrial energy, and a smarter longevity routine. Visit get.sunlighten.com/natpodcast and use code natlongevity to get $2,100 off + FREE shipping. Apollo Neuro — A wearable nervous system support device that uses personalized SmartVibes technology to help you feel calmer, more focused, and better able to shift into rest mode without adding another complicated wellness routine. Head to apolloneuro.com/nat Offer to receive 20% off. Vampire Exosome by Young Goose - A next-generation serum packed with three trillion PRP-derived exosomes and RejuvNAD to support collagen production and skin renewal at the cellular level—helping results build over time instead of fading fast. Shop at younggoose.com and use code NAT10. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Your skin has a biological age and for most people, it's not the same as their chronological one. Mayo Clinic published the SkinSpan framework this year specifically to quantify it, and the 12 Hallmarks of Aging now have a direct application to dermal tissue.This raises an uncomfortable question: if you're already optimizing everything below the neck with NAD IVs, peptides, and red light, why is the skincare on your face still operating on a paradigm from 1987?In this new episode of the Biohacking Beauty Podcast, we give you a preview of the keynote we're delivering at Dave Asprey's Beyond Conference and walk you through the 3-pillar framework that replaces traditional anti-aging skincare with longevity science in mind.Because the results you can feel today and results you can measure in ten years are not the same thing. And we think you deserve both.Let's dive in.What's Discussed:(2:29) The gap no one in longevity talks about.(3:06) Why your moisturizer is 38 years behind your supplements.(6:21) The 12 Hallmarks of Aging, decoded.(9:42) Pillar 1: The master pathway of skin aging.(12:18) Why NAD in a jar doesn't work (and what does).(14:22) The cellular housekeeping system that quietly shuts down with age.(15:17) The peptide that affects 32% of your skin's genome.(16:55) Pillar 2: The software updates your cells stop sending.(20:09) The PRP lineage that changed regenerative aesthetics.(22:54) Pillar 3: The pillar our community doesn't want to hear about.(29:09) The protocol, tiered by where you're starting.(37:55) How Young Goose fits into what you're already doing.(40:32) The two tests we're building to measure skin longevity.Find more from Young Goose:Use code PODCAST10 to get 10% off your first purchase, and if you're a returning customer use the code PODCAST5 to get 5% off at https://younggoose.comInstagram: @young_goose_skincareHead to younggoose.com/products/youth-body-cream for 20% off

George Wright III interviews Christie Steiger of Innovative Wellness Center about optimizing health for high achievers through comprehensive lab work, individualized functional medicine, and quantum hair analysis to identify cellular stressors like mold, parasites, viruses, toxins, and nutrient deficiencies. Christie shares how chronic symptoms such as fatigue, gut issues, headaches, insomnia, anxiety, brain fog, and weight gain often go unresolved in traditional care, and explains their clinic's approach, including targeted IVs and education via the Zyra Life Coaching Collective. They discuss peptides as cellular signaling tools, warning against unregulated online sources and emphasizing provider oversight, pharmacy-grade products, proper cycling, and personalized “stacks.” Christie describes reversing her own Health issues and being told she'd “forever have diabetes,” and recommends annual comprehensive labs plus at least one quantum test to establish personal benchmarks and trends.00:00 Exhausted and Unwell00:54 Welcome and Big Theme01:53 Christie's Origin Story03:09 Who They Help04:33 Labs and Root Causes05:45 Quantum Testing Explained09:04 Gut Fatigue Sleep Issues10:38 IV Drips and Coaching11:41 Peptides Basics and Risks14:47 Popular Peptides and Stacks15:48 Going National With Education17:14 Christie's Turnaround Story19:34 Where to Start Testing21:40 How Often to TestThanks for listening, and Please Share this Episode with someone. It would really help us to grow our show and share these valuable tips and strategies with others. Have a great day.George Wright III“It's Never Too Late to Start Living the Life You Were Meant to Live”FREE Daily Mastermind Resources:CONNECT with George & Access Tons of ResourcesGet access to Proven Strategies and Time-Test Principles for Success. Plus, download and access tons of FREE resources and online events by joining our Exclusive Community of Entrepreneurs, Business Owners, and High Achievers like YOU.Join FREE at DailyMastermind.comFollow me on social media Facebook | Instagram | Linkedin | TikTok | YoutubeGrow Your Authority and Personal Brand with a FREE Interview in a Top Global Magazine HERE.Christie Steiger is the Founder of Innovative Wellness Center and the reigning Mrs. Iowa 2025, dedicated to revolutionizing patient care through the principles of functional and integrative medicine. With over six years of experience in the health sector, including her tenure as a Functional Medicine Consultant at Zyra Life, Christie specializes in a comprehensive approach that merges Integrative Family Practice, Holistic Pain Management, and Longevity Treatments. At her center, she leads a team providing cutting-edge solutions such as Hormone Replacement Therapy (HRT), PRP, and advanced laser aesthetics. A graduate of the health and financial sectors with a background in business development, Christie empowers individuals to achieve transformative wellness by aligning innovative technology with deep-rooted holistic health values.Innovative Wellness Center

Discover how PRP hair loss treatment works—from the science behind platelet-rich plasma to real results, session timelines, and why Seoul is the new hotspot for this treatment. Learn what to expect, costs, and whether you're a good candidate. More info at https://www.lydianclinic.com/stemcelleng/hair-loss-treatment/ Lydian Cosmetic Surgery Clinic City: Seoul Address: 836 Nonhyeon-ro, Sinsa-dong, Gangnam Website: https://www.lydianclinic.com/

Connect with the Investor Mama Tribe Kim Rogne is a Certified High Performance Coach, Keynote Speaker, and the bestselling author of For The Love of Self – How to Change Your Mindset in Just 5 Minutes a Day. With over 25 years in the real estate industry, including 10 years in leadership management, Kim gained the expertise needed to launch her personal and professional development company, For The Love Of. She empowers working moms and small business owners to create balance, achieve more, and discover their own ‘For The Love Of.’ Kim is known for her unique approach to personal growth and productivity, bringing clarity and actionable steps to those feeling overwhelmed by life's demands. Her passion lies in helping others unlock their mindset superpower through her signature PRP Model (Potential = Reality = Perception), offering practical strategies that work both at home and in the workplace. As a self-proclaimed ‘mini-library’ of knowledge, Kim shares insights from books, podcasts, and her journey as a mom of two and her 27-year marriage. After a traumatic skiing accident left her wheelchair-bound, Kim took time off for the first time in 25 years. During this forced slow-down, she decided to stop dreaming and start doing, launching her business at age 50. Her company's vision is to inspire, empower, and promote action so everyone can live their best ‘For The Love Of’ life—allowing each person to fill in the blank with what matters most to them. Key Takeaways: 1. CEO Your Home — Stop Doing It All Yourself Treat your home like a business. Assign age-appropriate responsibilities to your kids (laundry, packing lunches, managing their schedule). Your worth is NOT in doing everything. Delegate just like you would at work — and don’t apologize for it. Start today: Pick one task you do daily and hand it off to your child or partner. 2. Create a Family Email + Shared Google Calendar Set up a dedicated family email that everyone has access to. All school newsletters, activity sign-ups, and events go there — not your personal inbox. As soon as kids are old enough, they update the family calendar themselves. Start today: Create a free Gmail family account and forward all school/activity emails there. 3. Use the “48-Hour Cart Rule” for Purchases Before buying anything over a set family threshold (Kim uses $50), it must sit in the cart for 48 hours. This one habit fights impulse spending and teaches kids delayed gratification — in your personal life AND your business. Start today: Set your family’s dollar threshold and make it a household rule. 4. Ask “What’s the ONE Thing?” to Beat Overwhelm When you feel buried, stop and ask: “What is the ONE thing I can do right now that will make everything else easier or unnecessary?” It might be making your bed, clearing the kitchen, or getting up 15 minutes early. Small wins protect your mental energy. Start today: Identify your one “sacred space” that, when tidy, gives you calm — and protect it. 5. Do 5-Minute Daily Journaling with These 6 Prompts Kim’s PRP journaling method (used to build a six-figure business in 12 months): Today I will release… Today I take in gratitude for… My core focus today is… Today I GET to… (opportunity, not obligation) I am… (affirmation or future manifestation) I will… (one action you’ll take) Start today: Grab any notebook and spend 5 minutes each morning on these 6 prompts. Download Kim’s free version at floself.com (or floworkingmoms.com for the working mom edition). Additional Resources and Help Support the Show Check out the Intern Strategy Course created by Christina from Smart Influencer Learn How to Make Extra Money with a Side Hustle or Get a High Paying Salary with Time Flexibility Episode #30:The #1 Side Hustle for the On the Go Busy Mom with Mike Yanda and Bobby Hoyt Episode #52: Millionaire by 31 and How to Start An ETSY Side Hustle Business with Julie Berninger from Gold City Ventures Check out Julia’s Sidehustle course to get started today The Legacy Binder to help you organize all of your estate documents and plans in case of an emergency Show Me How To Fix My Pelvic Floor from Tighten Your Tinkler Use Coupon Code: INVESTORMAMA to save $50 off this signature program High-income earner, needing an amazing accountant? Check out the TaxGoddess Connect with Kim Kim Rogne For The Love of Self: Change Your Mindset in Just 5 Minutes a Day LinkedIn Facebook Instagram

What if your sex life didn't have to decline with age — but could actually get better? Susan Bratton, intimacy expert and educator to over 1.5 million people worldwide, joins Dr. Debra Durst for one of the most wide-ranging, honest, and genuinely life-changing conversations about sexual health ever recorded on this channel. From fighting for your erectile function in your 30s to unlocking the female pleasure system most doctors completely ignore — this episode covers everything you didn't know you needed to know about having the best sex of your life right now, at any age.

Dr. Deb Muth 00:04What if the future of healing isn’t about replacing cells, but about teaching your body how to heal itself again? We keep hearing the words stem cells and exoomes thrown around like they’re interchangeable, but they’re not. One is regulated, controversial, and often misunderstood. The other is rapidly emerging as one of the most exciting communication systems in human biology. Dr. Deb Muth 00:33And here’s the real question no one’s asking. Are we actually regenerating tissue or are we just stimulating the body to remember how it used to heal? Tired of being told your labs are normal, but you still feel terrible? At Serenity Healthcare Center, we don’t chase symptoms. We find the root cause. hormones, gut health, autoimmune conditions, chronic fatigue, brain fog. Dr. Deb Muth 01:02We use cuttingedge functional and regenerative medicine to get you real answers and a real path forward. This isn’t your average doctor’s office. This is medicine the way it was meant to be practiced. You deserve to feel like yourself again. Visit serenityhealthcarecenter.com to book your appointment today. Let us help you heal from the inside out. Dr. Deb Muth 01:28Welcome back to Let’s Talk Wellness Now. I’m Dr. Deb, your host. And if you’ve been following regenerative medicine, you’ve probably noticed the confusion. Patients are asking me every week, are exoomes stem cells? Are stem cells legal in the United States? I heard the FDA is shutting down all these clinics. Can I even get this therapy? Do I have to leave the country for treatment? Today, we’re cutting through the noise. This episode is not hype. Dr. Deb Muth 01:54It’s not sales. It’s education so you can understand the science, the regulatory reality, and the clinical difference between stem cell therapy and exoome therapy. And here’s what I want you to know right up front. Yes, these therapies are being used in the United States every single day. Yes, they’re being offered by highly trained physicians in integrative and regenerative medicine clinics across the country. Dr. Deb Muth 02:22Some are being used in FDA registered clinical trials. Some are being used in observational studies and some are being used in clinical practice under physician discretion. The landscape is nuanced and you deserve to understand it. So, grab your cup of coffee or tea and settle in for a deep dive into the most understood therapies in regenerative medicine. Dr. Deb Muth 02:43what they actually are, how they work, the regulatory landscape, and how they might support your body’s natural healing capacity. Let’s talk wellness now. So, let me start by asking you something. When you hear the word stem cell, what do you picture? Most people imagine damaged tissues magically regenerating or a torn meniscus growing back, cartilage reforming it into an arthritic joint or damaged brain tissue being replaced with healthy new beautiful cells. It’s a beautiful vision. Dr. Deb Muth 03:15And while it’s not quite that simple, the reality is actually more sophisticated and honestly more beautiful. Stem cells are powerful and they absolutely work, but the way they work and the mechanism by which they support healing is far more elegant and more so than most people really understand. And if you’re going to invest in regenerative therapy, you deserve to understand what you’re actually receiving. Dr. Deb Muth 03:44So, let’s start at the beginning. What are stem cells? At their core, stem cells are undifferentiated cells. That means they haven’t yet decided what they want to be when they grow up. Unlike a heart cell or a skin cell or a bone cell which have already committed to a specific function, stem cells exist in this beautiful state of potential. Dr. Deb Muth 04:05They have two remarkable abilities. First, they can self-renew. They can make copies of themselves, maintaining a reserve of these powerful cells throughout your lifetime. Second, they can differentiate under the right conditions. They can transform into specialized cell types. Bone cells, cartilage cells, nerve cells, muscle cells, even blood cells. Dr. Deb Muth 04:27This is why they’ve captured the imagination of the medical world. The potential is extraordinary. Now, there are several types of stem cells and understanding the differences matters tremendously for both understanding how they work and understanding how they’re regulated. Adult mezzenymal stem cells. We call these MSC’s are the most commonly used regenerative medicine. Dr. Deb Muth 04:54These come from bone marrow, atapost tissue, that’s fat, and other adult sources. They’re what we can call multi-potent, meaning they can become several types of cells, but not every type. A bone marrow stem cell isn’t going to become a brain cell, for instance. It has potential but it’s directed potential. Dr. Deb Muth 05:19Then we have perinatal stem cells. These come from umbilical cord blood cord tissue or something called Wharton’s jelly which is the gelatinous substance inside the umbilical cord. These cells are younger, more potent, and research by Weiss and colleagues published in stem cells back in 2006 showed that Wharton’s jelly derived MSC’s have superior proliferation and differentiation potential compared to bone marrow derived cells. Dr. Deb Muth 05:48They’re like comparing a 20-year-old athlete to a 50-year-old athlete. Both can perform, but one has more reserve capacity, more vigor, and more regenerative potential. And this isn’t this is very important because the perinatal sources umbilical cord tissue Wharton’s jelly amniotic tissue these are what many regenerative medicine clinics in the United States are using today and they’re using them because these tissues are incredibly rich in not just stem cells but growth factors cytoines and exoomes. Dr. Deb Muth 06:21Then there are embryionic stem cells. These are pur potent and they become any cell type in the body, but they’re highly regulated, ethically controversial, and honestly, they’re not being used in clinical practice in the United States outside of the very specific FDA approved research trials. Dr. Deb Muth 06:41So, when clinics talk about stem cell therapy, they’re almost never talking about embryionic stem cells. Now, here’s where it gets interesting and this is the part that changes everything about how we understand regenerative medicine. When you receive stem cell therapy, let’s say someone injects umbilical cord derived messenymal stem cells into your arthritic knee, those cells do not typically engraft or become new tissue in any permanent way. Dr. Deb Muth 07:12They don’t set up shop in your joint and start cracking out new cartilage cells for the rest of your life. So what are they actually doing then? Well, in 2011, researchers Arnold Arnold Kaplan and Dennis Korea published a landmark paper in stem cells translational medicine that fundamentally changed how we understand MSC therapy. Dr. Deb Muth 07:35They proposed that we should stop calling memal stem cells and start calling them medicinal signaling cells. Why? Well, because their primary therapeutic benefit doesn’t come from what they become. It comes from what they secrete. Think of stem cells as incredibly sophisticated biological pharmacies. When you inject them into damaged tissue, that arthritic knee, that inflamed autoimmune condition, that injured brain, that don’t just sit there passively, they sense the environment. Dr. Deb Muth 08:07They detect inflammation. They recognize the tissue damage and they understand that the immune dysregulation is present and they see that and respond. They start pumping out hundreds of bioactive molecules, growth factors that tell your cells to repair and rebuild, cytoines that modulate inflammation, chemocines that recruit your body’s own healing cells to the area. Dr. Deb Muth 08:32And these tiny membranes bound packages called extracellular vesicles, including exosomes, which we’re going to talk about extensively today as well. These secreted factors are giving instructions to your native cells. They’re saying, “Let’s reduce inflammation. Let’s modulate your immune response. Let’s promote angioenesis. Dr. Deb Muth 08:53” That’s the formation of new blood vessels, bringing nutrients and oxygen. Let’s stimulate your own resident stem cells to wake up and get to work. Reduce cell death in damaged tissue and restore normal cellular function. This is called paracrine signaling. It’s the cellto cell communication. And this is where the real therapeutic power lives. Dr. Deb Muth 09:14The stem cells themselves, many of them die within days to weeks, but the cascade of healing they trigger, the signals they send, the programs they activate in your own cells, those effects can last for months or even years. Now, this understanding is crucial because it explains why both stem cell therapy and exoo therapy can be effective. Dr. Deb Muth 09:38The stem cells are powerful not because they become new tissue but because of the signals they send and exoomes are those signals isolated and concentrated. The biggest misconception in regenerative medicine is that stem cells replace tissue and in reality they coach healing more than they become healing. They’re biological educators teaching your body to remember how it used to heal before chronic inflammation, toxicity, and disease turned off all those programs. Dr. Deb Muth 10:12So if stem cells don’t exactly end graft and become the new tissue, if their power is in their signaling and then next logical question is why do we need the cells at all? Well, if we could isolate the messengers themselves, what if we could deliver just the communication systems without any of the complexity of the living cells? Well, that’s exactly what exosomes are. Dr. Deb Muth 10:38And they represent the cutting edge of regenerative medicine. So, let me paint you a picture of how cells actually communicate. Because for most medical history, we had it wrong. For decades, textbooks taught us that cells talk to each other in two basic ways. through direct contact like shaking hands or releasing signaling molecules that floated through the extracellular space like messages in bottles, simple chemical messages. Dr. Deb Muth 11:09But in the 1980s and 90s, researchers started discovering something far more sophisticated. cells were releasing these tiny membrane bound packages like a biological FedEx envelope kind of you know it was filled with complex specific cargo and these packages could travel through the blood cross the barriers that normally keep things out like bloodb brain barrier and deliver their contents to distant cells with remarkable precision. Dr. Deb Muth 11:38These are called extracellular vesicles. And exoomes are one of the most therapeutic important types. So what exactly are exosomes? Well, they’re nanosized vesicles, typically 30 to 150 nanome in diameter. To put that into perspective, a human hair is about 100,000 nanometers wide. These are incredible and most impossibly tiny. Dr. Deb Muth 12:09They’re released by virtually all cells in the body, but the most therapeutically interesting exoomes come from mezenymal stem cells. And those medicinal signaling cells we just discussed. And according to a landmark review of Raposo and Stervogal, they published in the journal of cell biology in 2013, exoomes are not cellular debris. They’re not waste products. Dr. Deb Muth 12:35They are precisely engineered communication vesicles or vehicles. Think of them as sophisticated delivery systems carefully packed, carefully labeled, and sent to specific destinations. very specific instructions. Inside each of these exoomes, you’ll find an incredibly sophisticated payload. They are microRNAs. These are small RNA molecules that can literally turn genes off or on in the recipient cells. Dr. Deb Muth 13:06They can tell a cell to start making more collagen, to reduce inflammatory proteins, to activate repair programs that have been shut down by chronic disease for a very long time. There are messenger RNAs, actual templates for protein production. And exoome can deliver these instructions for making healing proteins. There are proteins themselves, growth factors, cytoines, enzymes, all the molecular tools a cell needs to heal. Dr. Deb Muth 13:34And there are lipids, specialized fats that help the exoome membrane fuse with targeted cells, delivering the cargo inside. When an exoome reaches its target cell, it can either fuse the cell membrane and deliver its contents directly inside like a Trojan horse, or it can bind to surface receptors and trigger signaling cascades, setting off a chain reaction of healing responses. Dr. Deb Muth 14:01Either way, it’s delivering very specific targeted instruction. And here’s what makes this so powerful. Those instructions are tailored to what this recipient cell actually needs. So, let me give you some concrete examples of what the research actually shows because this is where it really gets exciting. When researchers inject MSC derived exoomes into hearts that had experienced eskeeia, reprofusion, injury, that’s damaged blood flow being cut off and then being restored. Dr. Deb Muth 14:36Kind of like what happens during a heart attack. Something remarkable happened. A study by Lei and colleagues published in stem cell research in 2010 showed that exoomes significantly reduced the size of the damaged area, reduced inflammatory cytoines that drive tissue destruction and promoted tissue repair signaling. The exoomes were telling the heart cells stop the inflammatory cascade, activate your survival programs and repair the damage. Dr. Deb Muth 15:06In cartilage research, tow and colleagues published work in biioaterials in 2017 showing that exosomes derived from MSC’s could promote cartilage regeneration in osteoarthritis models. And the exoomes carried specific microRNAs that told condondroytes cartilage cells to proliferate and make more extracellular matrix, the structural framework of healthy cartilage. Dr. Deb Muth 15:30for autoimmune conditions. Research by Blazic and colleagues in Frontiers in Immunology in 2014 demonstrated that MSC derived exoomes could shift immune cell behavior from pro pro-inflammatory to regulatory. They could take an overactive self-attacking immune system and restore balance and promote tolerance. And perhaps most exciting brain research, a study by Zinn and colleagues published in the journal of extracellular vesicles in 2013 showed that MSC derived exoomes could cross the bloodb brain barrier. Dr. Deb Muth 16:07That protective shield around your brain that normally keep things out and promote neurological recovery in stroke models. They reduced brain inflammation, promoted neuroplasticity, supported the formation of neural connections, and for mitochondrial dysfunction, which underlies so many chronic conditions, Morrison and colleagues published research and scientific reports in 2017 showing that MSC derived exoomes can actually deliver functional mitochondria or mitochondrial components to damaged cells. They’re not Dr. Deb Muth 16:40just sending instructions, they’re sending spare parts. They’re restoring the cellular powerhouses to produce energy. So why are exoomes fundamentally different from stem cells? Well, exoomes contain no living cells. They can’t replicate. They can’t end graph. And they have virtually no risk of immune rejection or tumor formation. Dr. Deb Muth 17:03Concerns that exist elevate rarely with cellular therapies. They’re essentially biological software updates for your cells. As Fineian Pitiger wrote in their seinal review in stem cells in 2017, MSC derived exoomes represent the active ingredient of stem cell therapy delivered in a cellfree format. That’s the key insight in the in the therapeutic benefit of stem cells and it comes from what they excrete. Dr. Deb Muth 17:33Then exoomes are the secretion isolated, concentrated, and standardized. From a practical clinical standpoint, exoomes offer several compelling advantages. First, consistency. Because exoomes can be isolated, characterized, and standardized, each dose can be remarkably consistent. With living stem cells, there’s variability based on donor age, health status, processing methods, and one batch may be robust, but another might be weaker. Dr. Deb Muth 18:05With exoomes, you can measure the content, measure the potency, and ensure the quality control. Second is storage. Exoomes can be liophalized. They can be freeze-dried and stored at room temperature or refrigerated for extended periods. Stem cells require cryopreserv preservation, careful freezing, careful thawing. They’re fragile. Dr. Deb Muth 18:31Exoomes are remarkably stable. And third, their safety profile. Without living cells, the risk of adverse imunological reactions is dramatically lower. You’re not introducing foreign cells that your immune system might recognize and attack. You’re introducing molecular messages. Fourth is scalability. You can harvest millions, even billions of exoomes from stem cell cultures without ever injecting the cells themselves. Dr. Deb Muth 19:01And you can produce large quantities, standardize them, and make them available to patients. Now, there is a caution here in doing this. The scalability can produce rogue cells, and we want to be cautious of that. So, here’s what I need you to understand. Exoomes don’t force healing. They remind the body how healing works. Dr. Deb Muth 19:24They’re not replacing damaged cells. They’re re-educating the cells you already have. They’re turning back time on the biological programs that got turned off by inflammation, toxicity, trauma, time, and chronic disease. Your body knows how to heal. It’s done its entire life. Every cut that closed, every bone that mended, every infection you fought off, your body orchestrated that healing. Dr. Deb Muth 19:51The problem is that chronic disease, chronic inflammation, toxic exposures, poor nutrition, stress, all of these things disrupt the communication networks that coordinate healing. And exoomes restore that communication. They’re like rebooting a computer that’s frozen. They reset the system and remind it how it’s supposed to function. All right. Dr. Deb Muth 20:14So, this would not be complete if we didn’t talk about regulation because this is where a lot of confusion exists. And I want you to be given a real picture. Not fear-mongering, not pretending. There aren’t regulatory considerations, but the actual practical reality of how regenerative medicine is practiced in the United States today. Dr. Deb Muth 20:38Here’s what you need to understand. The FDA regulates these therapies and they have specific frameworks, but there’s important nuances between regulatory text enforcement priorities and actual clinical practice. And there are also state level regulations that provide additional pathways. The FDA regulates human cells, tissues, and cellular and tissue based products. Dr. Deb Muth 21:05We call them HCT/PPS under two main pathways. Section 361 products are those that meet specific criteria. They’re minimally manipulated, intended for homologous use, meaning these tissues perform the same basic function in the recipient as it did in the donor. They’re not combined with non-tissue components and they’re either autotogus, meaning they come from your own tissue, or they have had minimal systemic effect. Dr. Deb Muth 21:38An example of a clear 361 procedure, your doctor harvests your own bone marrow, we call this PRP, performs minimally processing to or uh perform Yeah. performs minimal processing to concentrate the stem cells through a centriuge and injects it into your arthritic knee the same day. That’s autogus same day but minimally manipulated. Dr. Deb Muth 22:04This is unquestionably legal and is being done in regenerative medicine clinics across the country every single day. So there’s section 351 where products are those that don’t meet all the section 361 criteria. They’re classified as drugs or biologic products and they require FDA approval through clinical trials. Dr. Deb Muth 22:27Now here’s where this gets more nuanced. There are regenerative medicine clinics across the United States using stem cell and exoome therapies in different contexts. First FDA registered clinical trials. These are formal research studies with investigational new drug applications. Patients enroll in trials. They sign informed consents. Dr. Deb Muth 22:48They receive therapies as part of their structured research protocols. And this is completely legal and represents the gold standard for gathering evidence. Second is observational studies and registry programs. Many clinics are collecting systemic data on patient outcomes using these therapies even outside the FDA trials. Dr. Deb Muth 23:12They’re documenting results, tracking safety, and contributing to the growing body of clinical evidence. Third, there’s clinical practice under physician discretion. There are physicians using these therapies based on their own clinical judgment informed consent from patients and their interpretation of the regulatory framework particularly around minimal manipulation and homologous use. Dr. Deb Muth 23:34Now there are also state regulations that provide additional legal frameworks. So, for example, Florida has enacted the Right to Try Act and specific regenerative medicine legislation that allows physicians to offer certain stem cell therapies under the state oversight. Utah has passed similar legislation creating pathways for regenerative medicine products. Dr. Deb Muth 23:57And these state laws recognize that patients should have access to potentially beneficial therapies, particularly when used by trained physicians with appropriate informed consent. The regulatory question often centers around are these products minimally manipulated. Some products clearly are not. They’ve been cultured. Dr. Deb Muth 24:20They’ve been expanded in laboratories and those require FDA approval that they don’t have. The FDA has appropriately shut down clinics using those products. But there are other products that undergo processing that many physicians and manufacturers argue constitutes minimal manipulation. And these tissues are cleared, potentially fragmented or particulated to make them more suitable for injection, preserved using methods like cryopreservation or liophalization and packaged. Dr. Deb Muth 24:54But the cells are not cultured or expanded in the laboratory. The FDA has issued guidance suggesting that many of these processing steps constitute more than manipul minimal manipulation. But many physicians, particularly those who specialized in regenerative medicine for years, disagree with that interpretation and they believe that the processing qualifies as minimal manipulation and that the product should fall under section 361 when used for homologous purposes. Dr. Deb Muth 25:24Is there regulatory debate? Absolutely. The FDA and some clinicians have different interpretations of what constitutes minimal manipulation. But here’s the practical reality. There are hundreds of well-trained, bore certified physicians across the United States offering these therapies every single day. Dr. Deb Muth 25:42They’re doing so based on their understanding of the regulations, their clinical experience, their commitment to patient safety, and their belief that these therapies can help people who have exhausted conventional options. The FDA’s enforcement priorities have focused primarily on the most problematic cases. Clin clinics making blatant disease cure claims, products with documented safety issues, clear cases of cellular expansion and culture, or clinics operating with no medical oversight. Dr. Deb Muth 26:15Reputable regenerative medicine physicians are using products from companies that provide comprehensive documentation of their processing methods. third-party sterility testing, certificates of analysis showing bioactive content, and quality control measures that meet or exceed industry standards. Now, let me be very clear about something. Dr. Deb Muth 26:36Quality matters enormously. Not all stem cells and exoome products are created equal. Research by Burger and colleagues published in the Orthopedic Journal of Sports Medicine in 2021 analyzed 12 commercially available stem cell products and found that many contained zero viable cells, high levels of bacteria, endotoxins and inconsistent growth factor concentrations. Dr. Deb Muth 27:01This is why the company providing these biologic matters tremendously. You want products from manufacturers who provide transport documentation in sourcing and processing. Conduct third-party testing and sterility and potency. Offer certificates of analysis for each batch. Use standardized validated processing protocols. Dr. Deb Muth 27:24Have quality control measures that ensure consistency and don’t make outrageous cure claims or promise. The best regenerative medicine physician carefully vet their suppliers. They don’t use products from companies making unrealistic promises. They use products from manufacturers who are transparent, scientifically rigorous, and committed to quality. Dr. Deb Muth 27:46Now, you specifically ask about homologous use and collagen defects. So, let me address this directly for you. Under the FDA guidance, homologous use means the tissue performs the same basic function in the recipient as in the donor. So for connective tissue, tendons, ligaments, cartilage, fascia, all of that which are collagenrich structures using MSC’s or their derivatives could be considered homologous use. Dr. Deb Muth 28:17MSC’s in their native environment provide structural support to produce extracellular matrix including collagen. Using them to support healing in damaged collagen rich tissues like arthritic joints, torn tendons or degenerative ligaments is arguably the same basic function. So using exoomes derived from MSC’s to support collagen synthesis reduce inflammation and promote tissue healing in the same structures. Dr. Deb Muth 28:46Many practitioners argue this also qualifies as homologous use because you’re supporting the structure and function that MSC’s would naturally support. So here’s the bottom line on the regulatory reality. Regenerative medicine is available in the United States. It’s being offered by highly trained physicians in integrative and regenerative medicine clinics across the country. Dr. Deb Muth 29:11Some therapies are offered in FDA registered clinics and some are offered in observational studies. Some are offered in clinical practice under physician discretion, informed consent, and careful attention to safety. The regulatory landscape is evolving. There are ongoing discussions both federally and state levels about creating clearer pathways for these therapies. Dr. Deb Muth 29:32So, if you choose to go down this road, you want to work with physicians who understand the regulations, who use quality products from reputable manufacturers with rigorous testing and documentation, who are transparent about what they’re using and why, who discuss the current regulatory landscape honestly with you, and who prioritize your safety and truly informed consent above all else. Dr. Deb Muth 29:55This is not a lawless wild wild west. But it is also not as simple as everything is legal and unavailable. It’s a nuanced landscape that requires ethical knowledge. And these practitioners that have this knowledge have got to provide informed patients who understand both the potential benefits and the current regulatory context. Dr. Deb Muth 30:17So let’s have some fun here. Let’s talk about what really matters to you that are listening and that’s what conditions are being supported with these therapies. What does the research show and what are clinicians seeing in actual practice with patients? Because here’s what’s really important. We have both published research evidence and extensive clinical experience. Dr. Deb Muth 30:38And when the two align, that’s when we can feel confident and comfortable about using these approaches. So, let’s start where we have the most substantial evidence. joint health and muscularkeeletal conditions. For arthritis, we have good data. A systemic review by Tan and colleagues published in arthritis research and therapy in 2021 analyzed 20 randomized controlled trials in MSC therapy for knee osteoarthritis. Dr. Deb Muth 31:05They found significant improvements in pain and function particularly in mild to moderate disease. What’s really interesting is when researchers start analyzing whether it was the cells themselves or their secreted factors doing the work. They found that exoomeenriched preparations showed similar benefits to whole cell therapy. Dr. Deb Muth 31:26Now towen colleagues in the biioaterials paper from 2017 demonstrated that MSC derived exoomes could promote cartilage matrix synthesize and reduce inflammation markers. The exoomes carried microarnas that told cartilage cells to make more collagen and proteoglycans, the building blocks of healthy cartilage. Dr. Deb Muth 31:49In clinical practice, physicians are seeing patients with knee, hip, shoulder, and spinal arthritis, experiencing reduced pain, improved function, better motility, and in some cases, measurable improvements in their tissue. I want to share a story here with you because back in 2006, my husband was injured at work. Some of you might have heard me tell this story before. Dr. Deb Muth 32:11Um, he broke two discs in his back and underwent surgery very early on when we started using stem cells. They had put cages and plates in and they used MSC’s to put inside the cage to create a hardened bone so that he could have a fusion and hopefully not have any pain. At the time, what the physician didn’t realize or mistakenly did was he did not put any human bone mixed with these dead cadaavver bone MSC’s. Dr. Deb Muth 32:42And so the MSC’s never grew. They didn’t have anything to grow by. So the plates and the screws just kind of went back and forth for six months before he could see another physician that would look at him differently and understand what actually happened. That was very early on. Today we know so much more than we did before. Dr. Deb Muth 33:01Fast forward to 2014 when my husband was having problems and he couldn’t feel his legs, he couldn’t feel his feet. We decided to undergo uh exoo and stem cell therapy again and we saw a physician in Florida who harvested cells from his bone marrow and his blood and his fat and mixed that all together and then put that back into the back. Dr. Deb Muth 33:27and he had tremendous benefit from it. So, I tell this story because I want you to see the trajectory of how long this has been going on that we’ve been using this and we’re learning as we’re going and things are changing rapidly in this in this world. And so, what we know today and what I’m teaching you today may very well change in a month or six months or a year from now, but we have the foundation at least to understand what is helpful, what is not right now. Dr. Deb Muth 33:54But just be aware that if you’re embarking on exoome or stem cell therapy or MSC’s that you understand that this terrain is going to change. So back to my conversation about what other things can we treat? Well, we can treat tendon and ligament injuries, chronic tennis elbow, Achilles tendonopathy, rotator cuff tears, chronic planter fasciitis. Dr. Deb Muth 34:17These were researched by PA and colleagues in the American Journal of Sports Medicine in 2017 and it showed that bone marrow concentrate injections resulted in improved pain and function compared to steroid injections. Now this mechanism appears to be enhanced collagen remodeling and reduced chronic inflammation. Dr. Deb Muth 34:39These are structural collagenrich tissues using MSC’s or their derivatives for structural support which makes biological sense. It’s homologous use. It’s similar. So clinically we’re seeing athletes, active adults and people with chronic pain who failed physically um failed physical therapy, failed conservative treatments finding relief in this functional uh improvement in this functional world that we live in today. Dr. Deb Muth 35:07So, I want to be clear about what we’re doing here for joint and muscularkeeletal issues. We’re not growing completely new cartilage from scratch or severely destroyed joints. We’re not magically regenerating tissues that’s been gone for decades. That’s not possible here. What you’re doing when you’re using MSSE’s and exoomes is supporting the body’s natural ability to repair, reducing inflam inflammation and damage, and we’re driving progressive degeneration uh or we’re stopping the progressive degeneration. By reducing the Dr. Deb Muth 35:41inflammatory damage, we’re stimulating resonant stem cells that have been dormant. We’re improving blood flow and uh uh oxygen to the tissues like cartilage and tendons. and we’re organizing the body to start creating its own quality collagen as it heals. So, it’s a regenerative support, not a tissue replacement. Dr. Deb Muth 36:07But for many people, this support is lifechanging. So, let’s talk about autoimmune disorders now because this is one of the most exciting and unrecognized applications. autoimmune conditions like rheumatoid arthritis, lupus, MS, Crohn’s disease, ulcerative colitis, Hashimoto’s, they all involve the immune system and the immune system is deregulated. Dr. Deb Muth 36:30And so basically your immune system is seeing this tissue as foreign and it’s attacking it. These MSC’s and their exoomes have profound immune modulatory properties. They don’t suppress the immune system like steroids or imunosuppressive drugs. They modulate it helping to restore balance. So for rheumatoid arthritis, research by Weang and colleagues in stem cells translational medicine in 2016 showed that MSC derived exoomes could shift the balance of immune cells, reducing pro-inflammatory TH7 cells that drive joint disruption uh and increase Dr. Deb Muth 37:08regulatory TE-C cells that maintain immune tolerance. So for MS, a clinical trial by Kasus and colleagues published in archives of neurology back in 2010 evaluated autotogus MSC therapy and MS patients and they found evidence of reduced disease activity, improved neurological function and decreased inflammatory uh lesions on MRI scans. Dr. Deb Muth 37:34The proposed mechanism is MSC’s and their exoomes reduce inflammatory cytoine production promote regulatory imu immune populations support remination of damaged nerves that is rebuilding the protective coating around the nerve fibers and it reduces bloodb brain barrier permeability which prevents immune cells from attacking their brain and spinal cord. Dr. Deb Muth 38:02And so for inflammatory bowel disease, the research by Barnholm uh sorry Barnhorn and colleagues in gut in 2020 showed that MS cell MSC derived extracellular vesicles could support mucosal healing and reduce inflammation in the gut lining. They appeared to restore intestinal barrier function, healing that leaky gut and modulating local immune responses. Dr. Deb Muth 38:30So in clinical practice, physicians are seeing patients with autoimmune conditions, experiencing reduced disease flares, decreasing the need for imunosuppressive medications, improving energy and quality of life, and in some cases extending periods of remission. But here’s what I want you to understand. Dr. Deb Muth 38:52When you see these therapies for autoimmune conditions, we are supporting immune regulation and reducing inflammatory damage. We are not treating or curing the disease in a conventional sense. These therapies work best as part of a comprehensive functional medicine approach that also addresses gut health because 70% of your immune system lives in your gut and environmental triggers like mold, heavy metals, chemical toxins that can drive autoimmune responses, chronic infections that can trigger immune disregulation, stress and nervous system imbalance. And Dr. Deb Muth 39:29these nutritional deficiencies are necessary to help improve the immune function. So regenerative therapy without addressing root causes is like bailing water out of your boat without plugging the hole. You might get temporary relief, but the underlying problem still remains. So let’s talk about neurological conditions. Dr. Deb Muth 39:52And this is where the science gets truly fascinating. for traumatic brain injury and concussion. Research by Zang and colleagues in the Journal of Neurot Trauma in 2015 showed that MSC derived exoomes could reduce brain inflammation, promote neuroplasticity, that’s the brain’s ability to rewire itself and improve cognitive outcomes in animal models. Dr. Deb Muth 40:17The exoomes crossed the bloodb brain barrier, delivered neuroprotective proteins and microRNAs. They reduced inflammation, supported mitochondrial function in injured neurons and promoted both new blood vessels from new blood formation and neurogenesis and the birth of new neurons occurred. Neurological recovery requires a multi-systematic approach. Dr. Deb Muth 40:42Exoomes may support neural repair, but they work best combined with hormone optimization, growth hormone, testosterone, thyroid, pregnnolone, mitochondrial support compounds like NAD, CoQ10, PQQ, carnitine, all of those things that we use traditionally in functional medicine. Now for stroke recovery, there was research by Zinn and colleagues in the journal of extracellular vesicles that showed MSC derived exoomes reduced the size of brain damage and improved neurological recovery in animal models. There was a Dr. Deb Muth 41:19Parkinson’s disease study done by Kimoji and colleagues in the movement disorders in 2018 that suggested that MSSE derived exoomes could support dopamineergic neuron survival and those are the cells that die in Parkinson’s and it can help to reduce neuroinflammation. Clinically, physicians are seeing improvements in patients with postconussion syndrome, chronic traumatic brain injury, early stage cognitive decline, and other neurodeenerative conditions. Dr. Deb Muth 41:52These are not cures, but meaningful improvements in cognitive function, mood, energy, and quality of life. Now, let’s talk about autism spectrum disorder very carefully here because this is a very sensitive but very important topic for families. There have been several clinical trials that have explored MSC therapy for autism. Dr. Deb Muth 42:16Liv and colleagues published research in stem cell translational medicine in 2013 showing improvements in social interaction, communication, and behavioral symptoms in children with ASD who received cord blood MSC’s. Dawson and colleagues in 2017 conducted randomized trial autotogus cord blood infusion and found modest improvements in social communication particularly in children with higher baseline immune dysregulation. Dr. Deb Muth 42:47The proposed mechanisms for modulation of neuroinflammation support the mitochondrial function because many children with autism show evidence of mitochondrial dysfunction, reduction of oxidative stress, improvement in gut brain access dysfunction and modulation of immune dysregulation. In clinical practice, some physicians are seeing improvements in some children, better eye contact, increased language development, reduced sensory sensitivities, improved social engagement, but responses vary significantly, and we cannot predict which children will benefit most. So for Dr. Deb Muth 43:26families considering regenerative approaches for autism, these therapies are supporting the body’s healing mechanisms, reducing neuroinflammation, supporting cellular energy production, modulating immune function. These should only be considered as part of a comprehensive biomedical approach that includes dietary interventions to address food sensitivities, support gut health, environmental toxin removal, particularly heavy metals and chemical exposures, gut healing protocols with targeted probiotics and nutrients, Dr. Deb Muth 44:00metabolic testing and targeted supplementation, and evidence-based on behavioral and developmental therapies. These therapies should only be pursued with practitioners who are honest about what we know and what we don’t know and who follow rigorous safety protocols who never promise cures and who view regenerative medicine as a tool in the comprehensive healing strategy, not a standalone miracle. Dr. Deb Muth 44:26Not only that, these therapies will most likely need to be given several times over the course of this person’s lifetime, possibly even on an annual basis. And this is really important because it is not a oneandone. It is not a one-sizefits-all, and it needs to be looked at as a long-term option for working with autism. So, since we’re looking at stem cells versus exoomes, living cells, with stem cell therapy, you’re receiving living cells that can survive in your body for days to weeks. Dr. Deb Muth 45:02With exoome therapy, there are no living cells, just biological messages they would have sent. So, replication stem cells can potentially replicate. Although therapeutically this happens minimally, exoomes cannot replicate. They deliver the cargo and then they are cleared by your body. With stem cells, it’s primarily paracrine signaling. Dr. Deb Muth 45:28They’re coaching your cells to heal. With exoomes, it’s pure signaling, pure reprogramming your cells without any cellular component. Stem cells as we talked about can be autotogus from your own bone fat, blood or um bone marrow or allergenic from umbilical cord tissue or Wharton’s jelly. Dr. Deb Muth 45:50Exoomes are typically derived from cultured MSC’s often from umbilical cord or bone marrow sources and both can be given by local injection for targeted treatment of joints and tissues and exoomes can be given intravenously for whole body systemic support. both have um low immun immunogicity. I can’t say that word today. Dr. Deb Muth 46:17But exoomes have even lower risk since they contain no cellular material. Now, it’s absolutely critical for you to understand that there are massive quality differences. We’ve talked about this earlier. I want you to be very aware of this and have a conversation with any of the practitioners that you’re considering undergoing this treatment with. Dr. Deb Muth 46:37Here is where it matters more than anything when you’re considering regenerative medicine, the quality of the products and the expertise of the practitioner. Because the reality is not all regenerative medicine products are created equal. We all know that when we take different supplements and not all practitioners understand these therapies at the same depth. Dr. Deb Muth 46:58You want to look for practitioners that are board certified or have some kind of specialized regenerative medicine training. You want to know their clinical experience. How much have they done these procedures? How long have they done this? You want honest communication about the evidence and the limitations in this. Dr. Deb Muth 47:17You want a comprehensive functional medicine approach to go along with these therapies. And you want somebody that’s transparent about their informed consent and their regulatory status. If you have people that are uh claiming that they can cure disease or giving you guarantees, that is not that is not a good practitioner to work with. Dr. Deb Muth 47:37If you have high pressure sales tactics, you need to decide today limited supply for a week. These are marketing manipulations. It’s not medical care. You want to be cautious of extremely low prices because quality regenerative products are expensive to source, process, and test. and store. And if somebody’s offering stem cells or exoomes for a few hundred dollars, seriously, you need to question the quality, the safety, and where they got this from. Dr. Deb Muth 48:09So before undergoing any regenerative therapy, make sure you’re having a very, very lengthy conversation with the person and so you truly understand exactly what you’re getting, how it’s going to be delivered, and what they’re going to do. If there’s one thing I want you to take away from today is that your body has remarkable capacity to heal when given the right biological signals and the right environment. Dr. Deb Muth 48:35Stem cells and exoomes are powerful tools for providing biological signaling that can reduce inflammation, modulate immune function, support tissue repair, and restore cellular communication that’s been disrupted by chronic disease and inflammation. These therapies are available in the United States through trained physicians working in FDA registered trials, observational studies, and clinical practice, and using quality products from manufacturers with rigorous testing and quality control. Dr. Deb Muth 49:04So before you invest in regenerative medicine, do your homework. Ask detailed questions about product quality and source. Verify the products come from reputable manufacturers with certificates of analysis, third-party testing. Work with experienced practitioners. And remember, no injection, no infusion, no biologic can overcome ongoing toxic exposure, chronic stress, poor nutrition, gut dysfunction, and inadequate sleep. Dr. Deb Muth 49:34True healing requires your body and you to actively participate in this healing. If you are unwilling to address the root causes and change the lifestyle factors that disrupted your health in the first place, the biologics can amplify your healing signals, but you have to create the internal environment where healing can actually happen. Dr. Deb Muth 49:56So, I hope this episode has helped you understand regenerative medicine more clearly. Share it with somebody who’s looking for healing beyond the conventional approaches. And until next time, this has been Let’s Talk Wellness Now. Have a blessed day. >> Welcome to Let’s Talk Wellness Now, where we bring expert insights directly to you. Dr. Deb Muth 50:16Please note that the views and information shared by our guests are their own and do not necessarily reflect those of Let’s Talk Wellness Now, its management, or our partners. Each affiliate, sponsor, and partner is an independent entity with its own perspectives. Today’s content is provided forformational and educational purposes only and should not be considered specific advice, whether financial, medical, or legal. Dr. Deb Muth 50:41While we strive to present accurate and useful information, we cannot guarantee its completeness or relevance to your unique circumstances. We encourage you to consult with a qualified professional to address your individual needs. Your use of information from this broadcast is entirely at your own risk. Dr. Deb Muth 51:00By continuing to listen, you agree to indemnify and hold Let’s Talk Wellness Now and its associates harmless from any claims or damages arising from the use of this content. We may update this disclaimer at any time, and changes will take effect immediately upon posting or broadcast. Thank you for tuning in. We hope you find this episode both insightful and thought-provoking. Listener discretion is advised.The post Episode 265 – The Future of Healing: How Exosomes Re-Educate Your Body to Heal Itself first appeared on Let's Talk Wellness Now.

Today, I have the honor of interviewing Dr. Doris Day, a board-certified dermatologist who specializes in cosmetic and longevity dermatology. She is also a clinical professor of dermatology at NYU, recognized for her dedication and excellence in teaching, and is widely regarded as a leader in the aesthetic dermatology field. In addition to her clinical work, Dr. Day is a medical journalist and a prominent media figure. In our discussion, we examine the basics of perimenopause and menopause from a pathophysiology perspective, including the 30% decline in collagen synthesis that occurs during the first five years of menopause. We explore the skin microbiome, inflammation, and inflammaging, and why hydration, electrolytes, reducing processed sugars, and eating a nutrient-dense diet can have such a visible impact on skin health. Dr. Day also explains her approach to facial balancing and how our bones, fascia, muscles, and fat pads age. We discuss topical agents, advanced interventions including lasers, microneedling, PRF, PRP, stem cells, and growth factors, and even touch on emerging research suggesting that certain laser treatments may help reduce the risk of skin cancer. Throughout the conversation, I also openly shared what I have done to support my skin. Stay tuned for today's fascinating conversation about menopause, skin health, collagen loss, and the evolving science behind modern aesthetic dermatology. IN THIS EPISODE, YOU WILL LEARN: The sudden skin changes many women experience during early perimenopause Dr. Day explains how she personalizes skincare routines for each patient How collagen synthesis rapidly declines during the menopause transition How hydration, sleep, and nutrition can visibly improve skin tone and puffiness How inflammation, blood sugar issues, and poor metabolic health contribute to inflammaging and visible skin aging Why facial balance is more important than trying to erase every wrinkle or line Dr. Day shares how she combines lasers, topicals, and recovery protocols to support skin healing and collagen production How fillers and other cosmetic procedures can create an unnatural appearance when used incorrectly Bio: Dr. Doris Day, MD, is a board-certified dermatologist specializing in cosmetic and longevity dermatology. She is a Clinical Professor of Dermatology at NYU Langone Health, where she has been recognized with the Award for Dedication and Excellence in the Teaching of Dermatology. Her leadership in aesthetic dermatology has earned her the AAD Presidential Citation and the American Skin Association Award for leadership in dermatology. Ranked #3 in the United States and #1 in New York by Newsweek as a Top Cosmetic Dermatologist, Dr. Day is a recognized authority in her field. Her work has been cited in leading publications, including The New York Times and Castle Connolly's NY Magazine Top Doctors listings, for over 20 consecutive years. Dr. Day is also a medical journalist and a prominent media figure, providing expert commentary on major television programs and podcasts. Her insights are regularly featured in top magazines, and she is a sought-after speaker, delivering numerous lectures every year on cutting-edge aesthetic techniques at both national and international conferences. Dr. Day has over 100 publications in the medical literature, and she has written four best-selling books: "Rebooting the Biome" (2023), "Beyond Beautiful" (2018), "Forget the Facelift," and "100 Questions and Answers about Acne." She also hosts a popular dermatology show on SiriusXM's Doctor Radio, a platform where she has been educating the public for over 15 years, earning the AAD's Golden Triangle Award for Media Excellence. Her professional affiliations include the American Society for Dermatologic Surgery, where she has served on the board of directors; the American Academy of Dermatology, where she was recently elected to the nominating committee; the New York State Dermatology Society; and the American Honors Society of Dental and Facial Aesthetics. Dr. Day earned her BA in English from Columbia University, an MA in Journalism and Science Writing/Medical Reporting from New York University, and her MD from SUNY Downstate College of Medicine. She completed her dermatology residency at Cornell University College of Medicine, where she served as Chief Resident. Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia's website. Submit your questions to support@cynthiathurlow.com  Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.  Cynthia's Menopause Gut Book is on presale now! Cynthia's Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Dr. Doris Day On her website Instagram, Facebook, and TikTok

PRP 007 Mini-Broadcast: Episode 10 – The Man with the Golden Gun (With Robbie Sims) This is a rarity as far as Permanent Record Podcast episodes go.  Yes, it's an episode with show notes penned by Brian and not Sarah.  Sarah has one job once the episode has been recorded: to write the show notes.  But this time, she was nowhere to be found and everyone's second-favorite host, who already does so much, was left holding the bag!   I guess I'll start with the stuff that is ALWAYS part of these 007 episodes..... Since the beginning of the show, Brian has done his best to strong-arm discussion of Agent 007 into as many podcasts as he could. Finally he convinced Sarah to embark on a new mission: the Permanent Record Podcast 007 Mini-Broadcast! This occasional series from your friends Brian & Sarah started with "Dr. No" and will work its way up to the most recent Bond adventure, and on the way, it will discuss and critique all of the 007 theme songs and other relevant recordings. It's a dream come true for one of the hosts - and for Bond fans everywhere! Speaking of Bond fans everywhere, they will no doubt be delighted to learn that Robbie Sims, author of the delightful book Quantum of Silliness: The Peculiar World of Bond, James Bond, can once again be found co-hosting this installment with Brian and Sarah. So, with this ninth 007 movie, John Barry returns to the fold and provides one of his most controversial title tracks!  The PRP crew is going to break it down, give you the full story of how the score and the theme came to pass, and let you know what critics the world over think about it.  They will also discuss the actual film, to see if any of them will claim to love/enjoy/like it.  And somehow we get through the entire 90-minute show WITHOUT MENTIONING NICK-NACK!!!  That seems almost impossible, I know! Along with all of the MWTGG content, Robbie, Brian, and Sarah also talk about the new Lana Del Ray Bond theme, "First Light", co-written with legendary 007 composer David Arnold.  And of course, the three hosts also spill all the details on Robbie's recent vacation to Thailand, where he visited a few movie locations, including Khao Phing Kan AKA James Bond Island!  It sounds like a blast!! And finally, before it all ends, Robbie is put to the test again with a series of Bond trivia questions, but not before he makes plans to update his will and Brian makes the most shameful plea for free/discounted stuff in the history of the podcast.   As Sarah usually states:  It's an episode full of excitement, fun, and laughs that you won't want to miss! Find Robbie Sims at https://www.instagram.com/quantumofsilliness https://www.threads.net/@quantumofsilliness https://bsky.app/profile/quantumofsilliness.bsky.social   You can purchase Quantum of Silliness at https://thehistorypress.co.uk/publication/quantum-of-silliness/ or other reputable booksellers.   Read more at http://www.permanentrecordpodcast.com/ Visit us at https://www.facebook.com/permrecordpodcast You can also find us on Threads: https://www.threads.net/@permanentrecordpodcast Check out some pictures at https://www.instagram.com/permanentrecordpodcast/ Join the ever-growing crowd on BlueSky: https://bsky.app/profile/permrecordpod.bsky.social Leave a voicemail for Brian & Sarah at (724) 490-8324 or https://www.speakpipe.com/PermRecordPod  - we're ready to believe you!

Recording from a doctor's office before a PRP facial, Coco Dee expands on “girl math” and how jokingly justifying spending (like buying more because it's on sale) can keep women stuck, especially those who already struggle with money. Coco reframes money as a simple game with clear parameters, pointing to compound interest as proof of how powerful small, consistent choices can be over 10–20 years and how “girl math” can compound against you, too. Her core reminder is that today's decisions are seeds: you often feel the results two to three years later, just like training or leaving an unhealthy relationship has a messy middle before the payoff. She encourages being expansive, but not reckless, and to make choices that build wealth, legacy, or a financial buffer.00:00 Doctor Office Intro00:26 What Girl Math Means02:01 Money Game and Compounding03:41 Choices Plant Seeds05:01 Messy Middle and Rewards06:03 Garden Analogy for Money06:26 PRP and Skin Investment07:08 No Scrooge Final Reminder07:33 Wrap Up and Goodbye If you're after some more goodiesI have a FREE 5-Day Mindset Reset for you called  Wealthy Women WinYou can also follow me on Instagram

 Communication shapes how teams learn, respond, correct, and build trust. Trace Blackmore, CWT welcomes returning guest Paule Genest, Director, Sales and ESG (Environment, Social and Governance) Water and Energy TGWT / The Tannin Guys for a conversation on positive communication, temperaments, the WOW Effect, and how water professionals can use words with more clarity and care.    Communication With a Positive Impact  Paule reframes positive communication as communication with a positive impact. The goal is not fake positivity or polished language. The goal is to use the right words, tone, timing, and listening habits to create better emotional and relational outcomes.  That distinction matters in technical environments. Teams may say they want innovation, accountability, safety, or trust, but unclear or defensive communication can unintentionally create the opposite result. Paule reminds listeners that communication is not optional. It is operational.    Listening, Temperaments, and Shared Definitions  Trace and Paule revisit the temperament framework made familiar to Scaling UP! Nation through Kathleen Edelman's past appearances. Paule identifies herself as a "yellow," while Trace identifies as a "red," creating a useful example of how different communication styles can either complement or frustrate one another.  They also discuss why listening is more than waiting to respond. Paule encourages listeners to pay attention to words, nonverbal cues, context, environment, and emotion. She also emphasizes the importance of shared definitions. A word like "innovation," "courage," or "accountability" may not mean the same thing to every person in the room.    The Fizz Factor  Paule introduces the idea of "just enough fizz" in communication. Fizz is the energy, care, authenticity, and clarity that makes communication feel alive without becoming fake, overwhelming, or unclear.  Too little fizz can make communication flat. Too much can create noise. The professional challenge is learning how much energy, directness, empathy, and clarity the person and the situation require.    When Communication Gets Difficult  The conversation also addresses harder moments: tension in meetings, emotional escalation, apologies, safety corrections, and urgent technical situations. Paule encourages professionals to pause, breathe, validate, and revisit conversations when needed.  In a boiler room or safety-critical setting, direct communication may be necessary immediately. However, Trace and Paule agree that teams can still return later to review what happened, protect the relationship, and improve the system.  Better communication does not remove difficulty from technical work. It helps professionals handle difficulty with more clarity, humility, and purpose.  Listen to the full conversation above. Explore related episodes below. Stay engaged, keep learning, and continue scaling up your knowledge!    Timestamps  01:17 — Trace shares information about the Global 6K for Water and invites listeners to participate on Saturday, May 16. 02:20 — Trace introduces the episode topic: why clear, positive communication matters during busy seasons filled with projects, audits, customer calls, emails, and coordination. 03:28 — Words of Water with James McDonald 05:03 — Trace encourages listeners to visit the Scaling UP! H2O events page and highlights the 2026 Environment Systems Research Institute Conference in San Diego, California, July 13–17. 06:33 — Trace previews Legionella Awareness Month in August and explains why the podcast dedicates the month to Legionella, waterborne pathogens, expert interviews, and industry education. 08:29 — Trace introduces Industrial Water Week, taking place October 5–9, with daily themes for pretreatment, boilers, cooling, wastewater, and careers. 09:45 — Trace announces the return of Detective H2O during Industrial Water Week and reminds listeners why the week is designed to celebrate the industrial water treatment profession. 10:42 — Trace sets up the main interview by identifying miscommunication as a common professional challenge and introducing the need for better communication. 11:17 — Trace welcomes returning guest Paule Genest of TGWT Clean Technologies Inc. and references her previous appearances on Episode 192 and Episode 380 12:31 — Paule shares what she has been focused on since her last appearance, including growing relationships, improving communication, and supporting the water technologies community. 13:47 — Paule discusses her podcast-style work with power engineers and boiler operators, created to bring visibility to professionals who are often overlooked. 14:40 — Paule shares her work as an adjunct teacher at the University of Montreal, where her class on social responsibility and PR has become a required course. 15:23 — Paule talks about the Women of Water community, mentoring Abigail Coquette, and the value of documenting mentorship experiences for future learning. 16:05 — Trace reflects on an AWT Colorado Springs panel with baby boomers, Gen X, millennials, and Gen Z, showing how different generations respond to the same communication questions. 17:01 — Paule explains how she has learned to organize her communication around the listener and the message she wants them to take away. 18:30 — Trace introduces temperaments, with Paule identifying as yellow and Trace identifying as red, and connects the discussion to Kathleen Edelman's communication work. 19:31 — Trace explains why communication should be shaped for the recipient, using his Gen Z son and punctuation in text messages as an example. 19:54 — Paule explains that positive communication is not simply the opposite of negative communication, but a way of choosing words that influence emotional and relational outcomes. 21:40 — Paule emphasizes listening as an art and encourages professionals to pay attention to words, nonverbal cues, context, environment, and emotion. 22:43 — Paule explains why shared definitions matter, using "innovation" as an example of a word that may mean different things to different people. 23:54 — Paule discusses how people bring past experiences into present conversations and references I'm Okay, You're Okay and the child, parent, and adult framework. 26:00 — Trace asks Paule to explain her idea of "just enough fizz" in communication. 26:09 — Paule defines fizz as the energy, care, authenticity, vulnerability, and positive impact that help communication become more effective. 28:14 — Paule introduces the Fizz Factor Quiz and walks Trace through possible responses when tension rises in a team meeting. 29:29 — Paule compares communication styles to still water, espresso, sparkling water, and kombucha, helping listeners visualize different ways people show up in conversation. 30:30 — Paule explains the importance of speaking truth with empathy, checking tone and timing, and acknowledging how a message is received. 31:40 — Trace shares the example of a communication stick, where one person speaks until the other can accurately reflect what was said. 34:07 — Paule explains how to step back during emotional conversations by breathing, noticing physical cues, and returning to a listening mode. 37:10 — Paule reframes positive communication as "communication with a positive impact," focusing on the outcome it creates for both parties. 40:02 — Trace explains the three-part apology: acknowledging what happened, connecting with how it affected the other person, and asking how to make it right. 41:01 — Paule connects social responsibility with communication and explains why the outcome needs to be positive for both parties in a dialogue. 42:11 — Paule describes the communication model of speaker, listener, message, environment, noise, context, and feedback. 45:21 — After the sponsor break, Trace explains a question he uses when communication does not land as intended: "What did you just hear me say?" 45:55 — Paule suggests rating meetings and conversations by asking what each person felt, understood, and took away. 46:34 — Trace asks how communication changes in urgent safety situations, such as a boiler room issue that could lead to equipment failure or injury. 46:59 — Paule explains that direct safety communication may be necessary in the moment, but the team should revisit the conversation later to learn and preserve the relationship. 48:37 — Trace returns to the idea of "just enough fizz" and asks how to know whether the fizz is for the speaker, the listener, or the situation. 48:53 — Paule explains that fizz should respect both people, the situation, and the communication style of the other party. 50:47 — Paule shares how Melanie helped her realize that poetic communication still needs a clear action or outcome. 53:06 — Paule introduces Mathieu Laferrière's Feel, Know, Do approach as a practical structure for communication and email writing. 55:43 — Trace asks whether fizz works in email, where tone, facial expression, and visual cues are missing. 56:07 — Paule explains how to adapt the Feel, Know, Do structure for different temperaments, especially when writing to more direct communicators. 57:08 — Paule encourages listeners to ask people how they prefer to communicate, whether by email, text, Messenger, or another channel. 58:31 — Trace raises a practical technical example, asking whether fizz matters when simply reporting that a pump was out of prime. 58:54 — Paule explains that fizz is part of the experience and can still be present in technical updates through clarity, usefulness, and a human touch. 01:00:38 — Trace shares advice he received early in podcasting: it is okay to be impressed, but you have to be involved. 01:02:33 — Paule summarizes her key message: positive communication is not optional, it is operational. 01:03:15 — Paule begins the lightning round by creating a friendship holiday centered on writing a letter to yourself and to a friend. 01:04:52 — Paule shares her mantra, "Life is fragile," and connects it to people, the environment, Mother Nature, and water. 01:06:50 — Paule explains why she wishes more people understood the importance of boiler operators and power engineers. 01:10:21 — Trace summarizes the main lesson from the conversation: positive communication requires intentionally chosen words that help the other person understand the message. 01:11:16 — Trace explains how past experiences can shape miscommunication and why choosing words carefully can remove some of the "gray" in communication. 01:12:07 — Trace reflects on generational communication differences and encourages listeners to give others more grace.   Quotes "Be calm. Make sure your antennas are open and grab whatever is happening with the words, but also the nonverbal communication, the context, the environment."  "I would like to say that communication is not optional. It's operational."  "To be clear and check you know on our tone and timing, I've had to learn about my timing this year in hard ways."  "don't let kindness cloud the core message."    Connect with Paule Genest Phone: (514) 703-4317  Email: pgenest@tgwt.com  Website: TGWT: About | LinkedIn  LinkedIn: Paule (Paula) Genest, PRP, APR, Fellow CPRS, MCPRS | LinkedIn    Guest Resources Mentioned   The Gifts of Imperfect Parenting: Raising Children with Courage, Compassion, and Connection by Brené Brown PhD LMSW   Thanks for the Feedback: The Science and Art of Receiving Feedback Well by Douglas Stone (Author), Sheila Heen (Author)   I'm OK--You're OK: The Pioneering and Bestselling Self-Help Guide by Thomas Harris   Paule-Cast     Scaling UP! H2O Resources Mentioned  AWT (Association of Water Technologies)  Scaling UP! H2O Academy video courses  Submit a Show Idea  The Rising Tide Mastermind   192 The One With The Best Marketing Expert In The Water Treatment Industry  380 The WOW Effect: Women Leading Transformation in the Water Industry  117 The One With Temperament Expert, Kathleen Edelman   179 Another One that Teaches Us to Communicate Better with Others  281 The One About The Power of Kindness    Words of Water with James McDonald Today's definition is an electrochemical form of corrosion that occurs when two dissimilar metals are in electrical contact with each other in the presence of an electrolyte. Can you guess the word or phrase?    2026 Events for Water Professionals  Check out our Scaling UP! H2O Events Calendar where we've listed every event Water Treaters should be aware of by clicking HERE. 

In this episode, Prof Chapman explains the critical role mitochondrial health and energy metabolism play in egg competence and embryo development. He breaks down why egg quality declines with age, how chromosome errors happen, and the science behind popular fertility supplements like CoQ10, NADH, and DHEA. Prof Chapman also discusses emerging treatments such as PRP ovarian rejuvenation, why many therapies still lack strong clinical evidence, and what current research may hold for the future of fertility treatment. Explore the 'Prof. Michael Chapman - The IVF Journey' Facebook Page, your reliable destination for cutting-edge insights and guidance within the realm of In Vitro Fertilization (IVF). Don't miss out on the IVF Journey podcast; stay informed with the latest episode updates. Tune in for expert discussions and valuable information on navigating the intricate path of IVF.

In this episode of Better Edge, Elnur Babayev, MD, MS, physician scientist and reproductive endocrinologist, discusses a complex case involving diminished ovarian reserve, advanced reproductive age and complications following intra ovarian platelet rich plasma (PRP). Using this case as a lens, he examines the evidence gaps, safety concerns and opportunity costs associated with commercially marketed, unproven fertility interventions. The conversation highlights common misconceptions about ovarian “rejuvenation,” the limitations of ovarian reserve testing, and practical guidance for counseling, referral, and informed consent in caring for patients navigating reproductive aging.

Hey, Heal Squad! If your knees have been talking, your hips feel tighter than they used to, or you've ever wondered if joint pain just comes with getting older… this Throwback Thursday is for you. Maria sits down with top orthopedic surgeon Dr. Jason Snibbe for a fascinating conversation about joint health, mobility, and what we can actually do now to protect our bodies long-term. They get into the everyday habits that may be doing more damage than we realize, the truth about cortisone shots, PRP, robotic-assisted joint replacements, and how to know when pain has crossed the line from manageable to something you actually need to address. Dr. Snibbe also shares why muscle mass matters way more than most people think, how movement can either protect or break down your joints, and why joint replacement isn't the scary “end of the road” people imagine… it can actually be a brand new beginning! HEAL SQUAD SOCIALS IG: https://www.instagram.com/healsquad/ TikTok: https://www.tiktok.com/@healsquadxmaria HEAL SQUAD RESOURCES: Heal Squad Website:https://www.healsquad.com/ Heal Squad x Patreon: https://www.patreon.com/HealSquad/membership Maria Menounos Website: https://www.mariamenounos.com My Curated Macy's Page: https://stylecrew.macys.com/@mariamenounos EMR-Tek Red Light: https://emr-tek.com/discount/Maria30 for 30% off Airbnb: https://www.airbnb.com/host GUEST RESOURCES: Instagram: https://www.instagram.com/drjasonsnibbe/?hl=en  Website: https://www.drjasonsnibbe.com/ Snibbs Footwear: https://snibbs.co/ ABOUT MARIA MENOUNOS: Emmy Award-winning journalist, TV personality, actress, 2x NYT best-selling author, former pro-wrestler and brain tumor survivor, Maria Menounos' passion is to see others heal and to get better in all areas of life. ABOUT HEAL SQUAD x MARIA MENOUNOS: A daily digital talk-show that brings you the world's leading healers, experts, and celebrities to share groundbreaking secrets and tips to getting better in all areas of life. DISCLAIMER: This Podcast and all related content (published or distributed by or on behalf of Maria Menounos or http://Mariamenounos.com and http://healsquad.com) is for informational purposes only and may include information that is general in nature and that is not specific to you. Any information or opinions provided by guest experts or hosts featured within website or on Company's Podcast are their own; not those of Maria Menounos or the Company. Accordingly, Maria Menounos and the Company cannot be responsible for any results or consequences or actions you may take based on such information or opinions. This podcast is presented for exploratory purposes only. Published content is not intended to be used for preventing, diagnosing, or treating a specific illness. If you have, or suspect you may have, a health-care emergency, please contact a qualified health care professional for treatment.

What if being too flexible is exactly what makes surgery fail? And what if your doctor thinks your shoulder is fine because you can lift your arm to 90 degrees, not realizing that for you, 90 degrees might as well be a frozen joint? Your joints bend farther than most. But when something goes wrong, that same flexibility may be working against you and your surgeon may not know it yet. In this episode, Dr. Linda Bluestein sits down with Dr. Jocelyn Wittstein, orthopedic surgeon at Duke University, to pull back the curtain on one of medicine's most misunderstood intersections: hypermobility, connective tissue disorders, and orthopedic care. Why do surgeons sometimes refuse to operate on patients with hypermobility or EDS? What actually happens during an "atraumatic" dislocation and why does it feel so different from a typical injury? And how does estrogen quietly shape the strength of your connective tissue across your lifetime? Dr. Wittstein walks us through the critical distinction between joint laxity and instability a difference that changes everything about treatment. She explains the frozen shoulder paradox, where a hypermobile patient loses dramatic range of motion but still looks "normal" on paper. She breaks down what PRP can and cannot do, and when regenerative medicine is worth considering. And she reveals why surgical technique itself has to change when the patient has variant connective tissue. Whether you are managing chronic subluxations, weighing a surgical decision, or just trying to understand why your body plays by different rules this conversation gives you the framework to advocate for smarter care. Takeaways: Laxity Is Not Instability: Laxity is how far your joint moves. Instability is what happens when you can no longer control that movement. These are not the same problem, and confusing them leads to the wrong treatment. The Dislocation Spectrum: Hypermobile joints often dislocate with little or no trauma -- and reduce just as easily, because the tissues have more give and recoil. This is a fundamentally different mechanism than what surgeons typically train for. Why Surgery Gets Complicated: Surgeons may modify technique entirely for hypermobile patients using donor tendons or internal bracing, because standard repairs fail at higher rates when connective tissue itself is the variable. Estrogen and Your Joints: Estrogen influences collagen synthesis and joint inflammation. Its withdrawal during menopause can trigger increased pain and fibrotic conditions, including frozen shoulder, in ways that are rarely discussed. The Frozen Shoulder Paradox: A hypermobile patient presenting with 90 degrees of shoulder motion might look fine to any other doctor. For them, it may represent a catastrophic loss from baseline and will almost certainly be missed without the right clinical lens. What PRP Can (and Cannot) Do: PRP shows legitimate evidence for reducing inflammatory markers in mild arthritis. Bone marrow concentrate, despite the hype, has not yet proven superior. Know the difference before you invest. Want more Dr. Jocelyn Wittstein? @Jocelyn_wittstein_md https://ortho.duke.edu/jocelyn-r-wittstein-md Go to ⁠⁠cozyearth.com⁠⁠ and use my Promo Code: BENDYBOGO Go AquaTru.com now for 20% off (your purifier) using promo code BENDY. Want more Dr. Linda Bluestein, MD? Website: https://www.hypermobilitymd.com/ YouTube: https://www.youtube.com/@bendybodiespodcast Instagram: ⁠⁠⁠⁠https://www.instagram.com/hypermobilitymd/⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠https://www.facebook.com/BendyBodiesPodcast⁠⁠⁠⁠ X: ⁠⁠⁠⁠https://twitter.com/BluesteinLinda⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠https://www.linkedin.com/in/hypermobilitymd/⁠⁠⁠⁠ Newsletter: ⁠⁠⁠⁠https://hypermobilitymd.substack.com/ Shop my Amazon store ⁠⁠⁠ https://www.amazon.com/shop/hypermobilitymd Dr. Bluestein's Recommended Herbs, Supplements and Care Necessities: https://us.fullscript.com/welcome/hypermobilitymd/store-start Want to learn more about the UVA EDS Center? For Appointments and Questions: RUVAEDSCenter@uvahealth.org UVA EDS: https://www.uvahealth.com/healthy-practice/advancing-care-through-ehlers-danlos-clinic UVA EDS FAQ: https://www.uvahealth.com/support/eds/faq UVA Pediatric Integrative Medicine: https://childrens.uvahealth.com/specialties/integrative-health Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them. Join YOUR Bendy Bodies community at ⁠⁠https://www.bendybodiespodcast.com/⁠⁠. YOUR bendy body is our highest priority!⁠⁠ Learn more about Human Content at ⁠⁠⁠http://www.human-content.com⁠⁠⁠ Podcast Advertising/Business Inquiries: ⁠⁠⁠sales@human-content.com⁠⁠⁠ Part of the Human Content Podcast Network FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links Learn more about your ad choices. Visit megaphone.fm/adchoices

What if being too flexible is exactly what makes surgery fail? And what if your doctor thinks your shoulder is fine because you can lift your arm to 90 degrees, not realizing that for you, 90 degrees might as well be a frozen joint? Your joints bend farther than most. But when something goes wrong, that same flexibility may be working against you and your surgeon may not know it yet. In this episode, Dr. Linda Bluestein sits down with Dr. Jocelyn Wittstein, orthopedic surgeon at Duke University, to pull back the curtain on one of medicine's most misunderstood intersections: hypermobility, connective tissue disorders, and orthopedic care. Why do surgeons sometimes refuse to operate on patients with hypermobility or EDS? What actually happens during an "atraumatic" dislocation and why does it feel so different from a typical injury? And how does estrogen quietly shape the strength of your connective tissue across your lifetime? Dr. Wittstein walks us through the critical distinction between joint laxity and instability a difference that changes everything about treatment. She explains the frozen shoulder paradox, where a hypermobile patient loses dramatic range of motion but still looks "normal" on paper. She breaks down what PRP can and cannot do, and when regenerative medicine is worth considering. And she reveals why surgical technique itself has to change when the patient has variant connective tissue. Whether you are managing chronic subluxations, weighing a surgical decision, or just trying to understand why your body plays by different rules this conversation gives you the framework to advocate for smarter care. Takeaways: Laxity Is Not Instability: Laxity is how far your joint moves. Instability is what happens when you can no longer control that movement. These are not the same problem, and confusing them leads to the wrong treatment. The Dislocation Spectrum: Hypermobile joints often dislocate with little or no trauma -- and reduce just as easily, because the tissues have more give and recoil. This is a fundamentally different mechanism than what surgeons typically train for. Why Surgery Gets Complicated: Surgeons may modify technique entirely for hypermobile patients using donor tendons or internal bracing, because standard repairs fail at higher rates when connective tissue itself is the variable. Estrogen and Your Joints: Estrogen influences collagen synthesis and joint inflammation. Its withdrawal during menopause can trigger increased pain and fibrotic conditions, including frozen shoulder, in ways that are rarely discussed. The Frozen Shoulder Paradox: A hypermobile patient presenting with 90 degrees of shoulder motion might look fine to any other doctor. For them, it may represent a catastrophic loss from baseline and will almost certainly be missed without the right clinical lens. What PRP Can (and Cannot) Do: PRP shows legitimate evidence for reducing inflammatory markers in mild arthritis. Bone marrow concentrate, despite the hype, has not yet proven superior. Know the difference before you invest. Want more Dr. Jocelyn Wittstein? @Jocelyn_wittstein_md https://ortho.duke.edu/jocelyn-r-wittstein-md Go to ⁠⁠cozyearth.com⁠⁠ and use my Promo Code: BENDYBOGO Go AquaTru.com now for 20% off (your purifier) using promo code BENDY. Want more Dr. Linda Bluestein, MD? Website: https://www.hypermobilitymd.com/ YouTube: https://www.youtube.com/@bendybodiespodcast Instagram: ⁠⁠⁠⁠https://www.instagram.com/hypermobilitymd/⁠⁠⁠⁠ Facebook: ⁠⁠⁠⁠https://www.facebook.com/BendyBodiesPodcast⁠⁠⁠⁠ X: ⁠⁠⁠⁠https://twitter.com/BluesteinLinda⁠⁠⁠⁠ LinkedIn: ⁠⁠⁠⁠https://www.linkedin.com/in/hypermobilitymd/⁠⁠⁠⁠ Newsletter: ⁠⁠⁠⁠https://hypermobilitymd.substack.com/ Shop my Amazon store ⁠⁠⁠ https://www.amazon.com/shop/hypermobilitymd Dr. Bluestein's Recommended Herbs, Supplements and Care Necessities: https://us.fullscript.com/welcome/hypermobilitymd/store-start Want to learn more about the UVA EDS Center? For Appointments and Questions: RUVAEDSCenter@uvahealth.org UVA EDS: https://www.uvahealth.com/healthy-practice/advancing-care-through-ehlers-danlos-clinic UVA EDS FAQ: https://www.uvahealth.com/support/eds/faq UVA Pediatric Integrative Medicine: https://childrens.uvahealth.com/specialties/integrative-health Thank YOU so much for tuning in. We hope you found this episode informative, inspiring, useful, validating, and enjoyable. Join us on the next episode for YOUR time to level up your knowledge about hypermobility disorders and the people who have them. Join YOUR Bendy Bodies community at ⁠⁠https://www.bendybodiespodcast.com/⁠⁠. YOUR bendy body is our highest priority!⁠⁠ Learn more about Human Content at ⁠⁠⁠http://www.human-content.com⁠⁠⁠ Podcast Advertising/Business Inquiries: ⁠⁠⁠sales@human-content.com⁠⁠⁠ Part of the Human Content Podcast Network FTC: This video is not sponsored. Links are commissionable, meaning I may earn commission from purchases made through links Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of Dismantling You, I sit down with Dr. Jennifer Kulp-Makarov, a Board-Certified Reproductive Endocrinologist and founder of Fleura Fertility, trained at Johns Hopkins and Yale. We dig into how traditional fertility clinics often rely on a one size fits all approach to IVF, and why that can actually backfire for women with low AMH or those trying to conceive over 40. Dr. Jennifer shares the patient experience that changed everything for her: a woman who gave up on growing her family because she thought aggressive, high dose IVF was her only option. That moment became the catalyst for her to build a practice centered on personalized protocols and her signature Goldilocks approach to stimulation, finding the just right dose of medication rather than defaulting to the highest one.We also explore cutting edge fertility innovations including ovarian PRP, which is showing promise in improving markers like AMH and antifollicle count, and rapamycin, an emerging treatment that may help protect egg reserves and delay menopause. Dr. Jennifer breaks down how FSH dosing plays a critical role in egg competence and why monitoring it throughout the cycle, not just at baseline, makes a real difference. We talk about how fertility care is evolving to better support LGBTQ individuals through inclusive language and treatment design, and how AI could soon help standardize ultrasound data and embryo analysis. We wrap up with Dr. Jennifer's rapid fire answers on the most underrated factor in fertility, the biggest mistake patients make when choosing a clinic, and the one belief she had to dismantle in her own career.__________________________________________________Key Highlights

Today, I'm thrilled to welcome Dr. Nasha Winters back to the show for part two of our powerful conversation. As a trailblazer in integrative oncology and a passionate advocate for the “metabolic terrain” approach to health, Dr. Winters brings both deep expertise and a truly holistic perspective to the complex world of cancer and longevity. In this episode, she doesn't just share concepts—she takes us into the heart of what it means to test, assess, and address our own health in real life, especially when we're facing major diagnoses and difficult decisions. Episode Timestamps: Welcome & Introduction to Longevity Podcast ... 00:00:00 Metabolic Terrain Concept & Mitochondrial Health ... 00:05:00 The Test, Assess, Address Framework ... 00:08:08 Readiness, Honest Audit, and Lifestyle Evaluation ... 00:08:43 The Ten Terrain Drops in Cancer & Health ... 00:14:09 Emotional Foundations for Healing ... 00:15:01 Essential Lab Markers and the “Trifecta” ... 00:16:52 Affordable, Early Detection Labs—CBC, CRP, LDH, ESR ... 00:17:32 Shift Work, Circadian Health, and Mitigating Strategies ... 00:29:11 Handling Overwhelm: Prioritizing Fundamentals ... 00:37:45 Prevention Myths: Sun, Meat, and Food Access ... 00:42:26 Home-Cooked Food & Community's Healing Power ... 00:51:16 Behaviors That Seem Healthy But Aren't (e.g., Excess Cardio) ... 00:54:55 Age-Specific Advice and Building Longevity ... 00:56:25 Cancer, Metabolic Flexibility, and Biomarker “Under Five” Rule ... 01:02:32 Integrative Oncology's Strengths & Misconceptions ... 01:08:48 Risks of Extreme Alternative or Mainstream Approaches ... 01:12:58 Post-2020: Changing Health Trends & Immune Patterns ... 01:17:03 Hope for the Future & Patient Empowerment ... 01:24:02 Our Amazing Sponsors: STEMREGEN by Stemregen - A daily formula designed to support your body's natural repair systems by helping release your own stem cells into circulation, supporting recovery, resilience, and whole-body renewal at the source. Visit stemregen.co/NAT15 and use code NAT15. https://stemregen.co/NAT15 Vampire Exosome by Young Goose - A next-generation serum packed with three trillion PRP-derived exosomes and RejuvNAD to support collagen production and skin renewal at the cellular level—helping results build over time instead of fading fast. Shop HERE and use code NAT10. Bioregulators by Nature's Marvels - targeted peptides designed to support cellular signaling and renewal across key systems like circadian rhythm, immune function, and vascular health as part of a foundational longevity stack; head to profound-health.com and use code NAT15 for 15% off your first order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Today's word of the day is ‘superstation' as in Ted Turner as in TBS as CNN as TNT as in Cartoon Network as in the Atlanta Braves. Turner was a media titan. He won a World Series in 1995 in his final year of owning the Braves. He was philanthropic. He was a great man. (7:40) The Knicks got in done again. Up 2-0 on the 76ers and two wins away from an Eastern Conference Final. The Sixers played without Joel Embiid. Never healthy. The Spurs came back in Game 2 and just dominated the Timberwolves. Just another level of beatdown. (17:12) Is Luka going to come back for the playoffs? He has a very bad hamstring tear. He went to Spain for PRP injections. This was an 8 week injury. It's only been 5 weeks. (30:00) Review: I Love LA. (32:30) We are in the baseball twilight zone right now. The NL Central is on top of the baseball world. The American League looks like the upside down. Only the Yankees and Rays are above .500! (41:30) Let's take a look at the ERA leaders this season. It is quite the list. (46:00) Framber Valdez was suspended. AJ Hinch was suspended. (47:53) NPPOD. Learn more about your ad choices. Visit podcastchoices.com/adchoices

Today's word of the day is ‘superstation' as in Ted Turner as in TBS as CNN as TNT as in Cartoon Network as in the Atlanta Braves. Turner was a media titan. He won a World Series in 1995 in his final year of owning the Braves. He was philanthropic. He was a great man. (7:40) The Knicks got in done again. Up 2-0 on the 76ers and two wins away from an Eastern Conference Final. The Sixers played without Joel Embiid. Never healthy. The Spurs came back in Game 2 and just dominated the Timberwolves. Just another level of beatdown. (17:12) Is Luka going to come back for the playoffs? He has a very bad hamstring tear. He went to Spain for PRP injections. This was an 8 week injury. It's only been 5 weeks. (30:00) Review: I Love LA. (32:30) We are in the baseball twilight zone right now. The NL Central is on top of the baseball world. The American League looks like the upside down. Only the Yankees and Rays are above .500! (41:30) Let's take a look at the ERA leaders this season. It is quite the list. (46:00) Framber Valdez was suspended. AJ Hinch was suspended. (47:53) NPPOD. Learn more about your ad choices. Visit podcastchoices.com/adchoices

In this solo episode on androgenic alopecia, the host explains that hair loss is slow and progressive, driven largely by genetics and DHT-mediated miniaturization of follicles across the anagen, catagen, and telogen cycle, and stresses early detection using periodic photos of the temples, hairline/vertex, and crown. He frames hair growth as a "battle" between Wnt signaling (promotes growth and anagen entry via stem cell activation) and DHT signaling (suppresses Wnt and increases inhibitors like DKK, TGF-beta, and PGD2), noting advanced loss involves inflammation, fibrosis, and irreversible follicle loss. He reviews contributors like poor scalp blood flow, iron deficiency (most evidence), possible zinc/B12/folate deficiency, thyroid dysfunction, and insulin resistance, then covers treatments: finasteride (oral and topical) and dutasteride as DHT blockers with potential systemic side effects, plus minoxidil and microneedling (home vs professional) as key options, with add-ons like ketoconazole shampoo, PRP, red light, and cautions about anabolic steroids and high-dose testosterone increasing DHT pressure.   Hair loss diagnosis and treatment https://www.aad.org/public/diseases/hair-loss/treatment/diagnosis-treat Androgenetic alopecia https://medlineplus.gov/genetics/condition/androgenetic-alopecia/ DHT and WNT signaling https://pubmed.ncbi.nlm.nih.gov/29549490/ Finasteride https://medlineplus.gov/druginfo/meds/a698016.html Topical finasteride https://pmc.ncbi.nlm.nih.gov/articles/PMC6609098/ FDA warning on compounded topical finasteride https://www.fda.gov/drugs/human-drug-compounding/fda-alerts-health-care-providers-compounders-and-consumers-potential-risks-associated-compounded Post-finasteride syndrome https://pubmed.ncbi.nlm.nih.gov/35983808/ Dutasteride https://medlineplus.gov/druginfo/meds/a603001.html Minoxidil https://www.aad.org/public/diseases/hair-loss/treatment/diagnosis-treat Microneedling for hair loss https://pubmed.ncbi.nlm.nih.gov/23960389/ Ketoconazole shampoo https://pubmed.ncbi.nlm.nih.gov/31858672/ Topical caffeine https://pubmed.ncbi.nlm.nih.gov/39997270/ Pumpkin seed oil https://pubmed.ncbi.nlm.nih.gov/24864154/ PRP for hair loss https://pubmed.ncbi.nlm.nih.gov/30882509/ Red light / low-level light therapy https://pmc.ncbi.nlm.nih.gov/articles/PMC8906269/ Stem cells / exosomes for hair growth https://pmc.ncbi.nlm.nih.gov/articles/PMC12433634/ Iron, zinc, B12, and folate deficiencies https://pmc.ncbi.nlm.nih.gov/articles/PMC6380979/ Thyroid testing https://medlineplus.gov/thyroidtests.html Insulin resistance / metabolic syndrome https://medlineplus.gov/metabolicsyndrome.html Testosterone / TRT https://medlineplus.gov/druginfo/meds/a605020.html Tretinoin https://medlineplus.gov/druginfo/meds/a682437.html Anastrozole / Arimidex https://medlineplus.gov/druginfo/meds/a696018.html Anabolic steroids https://nida.nih.gov/research-topics/anabolic-steroids   Show Notes 00:00 Welcome to the Hart2Heart Podcast 00:56 What Is Androgenic Alopecia 02:17 Hair Follicle Life Cycle 03:55 Miniaturization and Early Detection 06:51 DHT Basics and Other Causes 09:27 WNT Versus DHT Explained 13:10 Nutrients Thyroid and Insulin 16:26 Finasteride Benefits and Risks 19:21 Topical Finasteride and Dutasteride 25:01 Minoxidil Growth Booster 27:19 Microneedling for WNT Activation 30:21 Extra Treatments and Add Ons 37:04 Testosterone TRT and Steroids 40:16 Wrap Up and Key Takeaways   The Hart2Heart podcast is hosted by family physician Dr. Michael Hart, who is dedicated to cutting through the noise and uncovering the most effective strategies for optimizing health, longevity, and peak performance. This podcast dives deep into evidence-based approaches to hormone balance, peptides, sleep optimization, nutrition, psychedelics, supplements, exercise protocols, leveraging sunlight, and de-prescribing pharmaceuticals — using medications only when absolutely necessary. Beyond health science, we explore the intersection of public health and politics, exposing how policy decisions shape our health landscape and what actionable steps people can take to reclaim control over their well-being. Guests range from out-of-the-box thinking physicians such as Dr. Casey Means (author of "Good Energy") and Dr. Roger Sehult (Medcram lectures) to public health experts such as Dr. Jay Bhattacharya (Director of the National Institutes of Health (NIH) and Dr. Marty Mckary  (Commissioner of the Food and Drug Administration (FDA) and high-profile names such as  Zuby and Mark Sisson (Primal Blueprint and Primal Kitchen). If you're ready to take control of your health and performance, this podcast is for you.We cut through the jargon and deliver practical, no-BS advice that you can implement in your daily life, empowering you to make positive changes for your well-being. Connect with Dr. Mike Hart Instagram: @drmikehart Twitter: @drmikehart Facebook: @drmikehart

In this episode of The Health Fix Podcast, Dr. Jannine Krause sits down with Dr. S. Don Kim, podiatrist and naturopathic physician with over 30 years of experience, to break down why foot pain becomes more common as we age and what you can do about it naturally. From hormonal shifts to changes in connective tissue and biomechanics, your feet go through a lot in midlife. Dr. Kim explains how your foot type (flat feet vs. high arches) impacts everything from posture to joint pain and why ignoring your feet can accelerate aging in the entire body. You'll also learn about his "Walking Cure" program, designed to gently rebuild strength, improve circulation, and reduce pain without aggressive exercise. Plus, we explore cutting-edge therapies like PRP, hyperbaric oxygen, and laser treatments that can help regenerate tissue and support long-term healing. If you want to stay active, mobile, and pain-free well into your 40s, 50s, and beyond this episode will give you a whole new way to think about your health from the ground up.   What You'll Learn in This Episode Why foot health is foundational to total body wellness How to identify your foot type (and why it matters) The biomechanics behind flat feet and high arches Root causes of heel pain and plantar fasciitis Holistic and regenerative approaches to healing How the "Walking Cure" can improve mobility and longevity Innovative therapies like PRP, hyperbaric oxygen, and laser treatments The connection between chronic disease and foot dysfunction   Timestamps 00:00 – Introduction to Dr. Don Kim 02:30 – Why foot health impacts your entire body 06:15 – Understanding foot types: flat feet vs high arches 12:40 – The real causes of heel pain 18:20 – Dr. Kim's "Walking Cure" explained 25:10 – Regenerative treatments beyond surgery 31:45 – PRP, hyperbaric oxygen & laser therapy 38:20 – Neuropathy, diabetes & foot health connection 44:00 – Practical tips to start healing your feet today   About Dr. Don Kim Dr. S. Don Kim is a podiatrist and naturopathic physician with over three decades of experience. As Medical Director of Kim Foot & Ankle Centers since 1991, he has developed deep expertise in heel pain and mobility restoration. He is also the founder of K Wellness Center, where he integrates holistic therapies to address chronic conditions such as diabetes, neuropathy, and fatigue. Connect with Dr. Kim   Connect with Dr. Jannine Krause Website: https://doctorjkrausend.com/

In this episode, Rena Malik is joined by Dr. Vonda Wright to discuss strategies for preventing joint degeneration and maintaining musculoskeletal health as we age. They explore the science behind joint structure, the impact of hormones, weight, and activity, as well as the latest treatments like platelet-rich plasma (PRP) therapy. Listeners will gain practical insights into proactive joint care and learn how to navigate new therapies and information in the ever-evolving landscape of sports medicine. Become a Member to Receive Exclusive Content: renamalik.supercast.com Schedule an appointment with me: https://www.renamalikmd.com/appointments ▶️Chapters: 00:00 What Causes Joint Degeneration 02:12 Why Arthritis Gets Worse in Midlife Women 04:00 Is Joint Pain an Inevitable Part of Aging? 04:31 Why Strength Training Protects Your Joints 05:40 Does Exercise Wear Out Your Joints? 06:53 Vibration Plates and Bone Health 07:51 PRP for Joint Pain and Healing 11:37 The Risks of Unregulated PRP Treatments 16:24 How PRP Can Improve Surgical Healing Stay connected with Dr. Vonda Wright on social media for daily insights and updates. Don't miss out—follow her now and check out these links! INSTAGRAM - https://www.instagram.com/drvondawright/?hl=en FACEBOOK - https://www.facebook.com/DrVonda/ YOUTUBE - https://www.youtube.com/user/vondawright X - https://twitter.com/drvondawright WEBSITE - https://www.drvondawright.com/ Unbreakable: A Woman's Guide to Aging with Power By Vonda Wright, MD - https://www.penguinrandomhouse.com/books/777365/unbreakable-by-vonda-wright-md/ Let's Connect!: WEBSITE: http://www.renamalikmd.com YOUTUBE: https://www.youtube.com/@RenaMalikMD INSTAGRAM: http://www.instagram.com/RenaMalikMD TWITTER: http://twitter.com/RenaMalikMD FACEBOOK: https://www.facebook.com/RenaMalikMD/ LINKEDIN: https://www.linkedin.com/in/renadmalik PINTEREST: https://www.pinterest.com/renamalikmd/ TIKTOK: https://www.tiktok.com/RenaMalikMD ------------------------------------------------------ DISCLAIMER: This podcast is purely educational and does not constitute medical advice. The content of this podcast is my personal opinion, and not that of my employer(s). Use of this information is at your own risk. Rena Malik, M.D. will not assume any liability for any direct or indirect losses or damages that may result from the use of information contained in this podcast including but not limited to economic loss, injury, illness or death. Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode, Dr. Koolaee is joined by Dr. Jonathan Gelber to discuss orthopedic biologics, including platelet-rich plasma (PRP) injections, infrared laser therapy, and exosomes. Today's Guest Dr. Jonathan Gelber is an orthopedic surgeon specializing in sports medicine and arthroscopic surgery, discussing non-surgical options for joint pain management. About Dr. Koolaee Dr. Michelle Koolaee did her training for internal medicine residency at St. Luke's Roosevelt Hospital and went on to do her fellowship at University of Pennsylvania for rheumatology, where she was named Fellow of the Year. She then became an assistant professor at the University of Southern California before working at organizations such as Healthcare Partners and Presbyterian Intercommunity Hospital. She currently practices at Huntington Health, an affiliate of Cedars-Sinai, and is now starting her own direct care practice. Links for Dr. Koolaee ⁠⁠https://www.drrmichellekoolaee.com/⁠⁠ ⁠⁠Facebook⁠⁠ ⁠⁠LinkedIn⁠⁠ ⁠⁠Instagram⁠ Learn more about your ad choices. Visit megaphone.fm/adchoices

This week, we're getting into everything we've been doing in the name of beauty—treatments, tweaks, and… stem cells?!Sara kicks things off with a full rundown of her recent visit to the new Things We Do location in West Hollywood, where she tried Sculptra, Skinvive, and PRFM (platelet-rich fibrin matrix). What is PRFM, how is it different from PRP, and why is everyone talking about it right now? Then, Kirbie shares her experience with a next-gen peel from Australian brand UltraCeuticals that she's eager to see the results of.And finally: we both took things to the next level with Acorn Bio Labs at Facile—yes, we did stem cell retrieval. We're breaking down what it is, why we did it, and what this could mean for the future of beauty (more to come here…).In news, we're talking about Susan Yara's new-ish brand launch: Playa. (Sound familiar? There's a reason.) What can we expect? We're breaking it down. Watch our episodes!Shop our episodesInstagram: @glossangelspod | TikTok: @glossangelespodEmail: glossangelespodcast@gmail.com Hosted on Acast. See acast.com/privacy for more information.

Episode 067 | Dr. Amanda Hill—Founder of RENEW Longevity & Medical Aesthetics—is a board-certified dermatologist specializing in longevity medicine, regenerative aesthetics, and precision-based care. She completed her dermatology residency at Stanford University (with Dr. Lewellis!), where she served as Chief Resident, and later served as Chief of Dermatology at Nellis Air Force Base, caring for service members and their families.Through her work with RENEW, Dr. Hill integrates metabolic health, hormone optimization, and skin longevity into comprehensive, individualized treatment plans. She has advanced training in bioidentical hormone therapy and regenerative aesthetics and is currently completing the A4M Longevity Medicine Fellowship (Spring 2026). Dr. Hill is an active member of Longevity Docs, the American Academy of Dermatology (AAD), and the American Board of Dermatology (ABD).Dr. Hill believes great skin is a reflection of overall health—not an isolated concern. With expertise spanning dermatology, nutrition, and regenerative medicine, she created RENEW to help women stop guessing and start healing. Her approach is thoughtful, data-driven, and deeply personal, focusing on how patients feel as much as how they look.Dr. Hill's areas of focus include: hormone-driven skin conditions such as acne, rosacea, and melasma; Aging-related concerns including skin laxity, dullness, and volume loss; Regenerative treatments such as PRP, laser therapies, and natural injectables; Integrative care that connects skin health, hormones, metabolism, and overall vitality.Outside the clinic, Dr. Hill is married, a mother of four, and a proud dog mom to two Golden Retrievers—bringing real-life perspective to her aspirational yet sustainable approach to longevity and wellness.More from Dr. Hill and RENEWInstagram: @amandahilldermdocLinkedIn: https://www.linkedin.com/in/amanda-hill-dermdoc Email: amandarayemd@gmail.comMore from Dr. Lewellis and Above & Beyond DermatologyNeed a dermatologist? Fill out this short interest form, text or call me at 715-391-9774, or email me at drlewellis@aboveandbeyondderm.com if you'd like to have a no obligation discovery call. I offer in-office visits, house calls, and virtual care in Wisconsin and virtual care in Illinois and Nebraska.Have an idea for a guest or want to be on the show yourself? Send me a text or email, and we'll see if it's a good fit.Above & Beyond DermatologyNutrafol -- special pricing and physician exclusive productsNeoGenesis -- my favorite source of stem cell released molecules for skin/hairSilagen.biz -- physician dispensed scar refinement products delivered to your door (use practice code 1206240832P)NewsletterLinkedInFacebookDr. Lewellis on InstagramAbove & Beyond Dermatology on InstagramYouTubeTikTokTwitter/XChange Your Mind, Change Your LifeSoMeDocs (Doctors on Social Media)This page may contain affiliate links.

If you've ever left your doctor's office with unanswered questions about your body, your pain, your leakage, or your sex life — you are not alone, and it is not okay. In this episode, Dr. Debra Durst sits down with Dr. Troy Hailparn, cosmetic plastic gynecologist, at the International Society of Cosmetic Gynecology conference to have the conversation most women never get to have with their doctor. From labiaplasty and vaginoplasty to PRP, radiofrequency, and the truth about estrogen — this episode is packed with the education, advocacy, and real answers that women have been searching for.

If you've ever felt overwhelmed by all the advice around Botox, fillers, skincare treatments, and hair growth, you are not alone. I've had so many of these questions myself, which is why I'm so excited to sit down with my good friend and trusted dermatologist, Dr. Jo Lynne Herzog, for this conversation. We're cutting through the noise and talking honestly about what actually works (and what's not worth your time or money). From injectables like Botox, Dysport, and Daxify, to how we can maintain facial volume as we age, to achieving glowy skin and improving texture—we cover it all. My hope is that you walk away feeling more informed, more confident, and less pressured to chase every new trend!   WHAT TO EXPECT IN THIS EPISODE What we think every woman needs to know before getting fillers The only filler Dr. Jo feels confident using on her patients' temples How we lose facial volume over time (and why a facelift isn't the full solution) Why you shouldn't chase trending treatments or "fad" injectables How Dr. Jo thinks about achieving glowy, "glass" skin in midlife Tips for maintaining smooth, healthy skin texture How Dr. Jo and I met—and why I trust her approach The differences between Botox, Dysport, Daxify, and other neuromodulators Why Botox is safe (even though it's technically a toxin) Whether microneedling with PRP is worth the extra cost What to do about crepey skin Dr. Jo's honest thoughts on peptides Why too much biotin is not a good thing Hair growth solutions, including oral minoxidil Whether permanent hair removal actually exists   LINKS & RESOURCES MENTIONED: Connect with Dr. Jo Lynne Herzog at Elite Skin Nutrafol Women's Hair Growth Supplements - Vegan Sunbetter SHEER SPF 56 Mineral Sunscreen Stick   WHERE TO LISTEN The SavvyCast is available on all podcasting platforms and YouTube. One of the best ways to support the show is by leaving a rating and review—I so appreciate you sharing your thoughts, my friends!   ENJOYED THIS EPSIODE? CHECK THESE OUT! Considering a Facelift? 10 Things to Think About Before You Say Yes Listen on Apple Podcasts or Spotify Watch on YouTube   Which Beauty & Skincare Treatments Actually Make a Difference (Botox, Sculptra, Microneedling, & More) Listen on Apple Podcasts or Spotify Watch on YouTube

If you're looking to reignite your enthusiasm for orthopaedic medicine, join Dr. Bruce Reider as he sits down with Dr. James Bradley, a renowned shoulder and knee surgeon, Clinical Professor at the University of Pittsburg School of Medicine, and Head team physician for the Pittsburg Steelers Professional Football Club for over 3 decades. From his early years as the captain of the Penn State football team, Dr. Bradley has an innate understanding of the complexities of caring for professional players and was an early adapter of PRP for clinical use. Whether you're interested in learning more about his research on posterior shoulder instability, recommendations on return to play, or updates on his golf game, this conversation will remind you of the impact of sports medicine!

Today, I'm joined by Todd Shipman, a curious mind who initially set out to debunk the world of quantum energy—and ended up completely rethinking how our biology, energy, and even our sense of connection really work. In this episode, Todd Shipman shares his surprising journey, from skeptic to quantum advocate, and walks us through what the quantum field is—using clear analogies that finally make sense of a subject that usually feels way too abstract. Visit quantumupgrade.io/NAT and use code NAT15 to start the free 15 day trial. Episode Timestamps: Introduction to the Longevity Podcast and host ... 00:00:00 Defining quantum energy on the subatomic level ... 00:05:39 What coherence means for health and energy ... 00:06:35 Wave and lake analogies for coherence/disruption ... 00:07:19 Modern EMFs, energetic chaos, and body responses ... 00:09:41 The quantum field as explained by Joe Dispenza ... 00:11:42 Becoming aware of the quantum field's presence ... 00:12:14 Personal experiments and shifting beliefs ... 00:13:12 Blood test with a quantum necklace ... 00:15:05 Relating quantum energy to sunlight and frequencies ... 00:17:46 Quantum tech, proprietary methods, and skepticism ... 00:18:46 Nobel Prize, entanglement, and scientific validation ... 00:21:24 Twins, connection, and quantum entanglement ... 00:22:27 Mother-child energetic connection ... 00:25:20 Summary of Nobel-winning quantum entanglement study ... 00:27:14 Quantum info transfer and "no distance" ... 00:29:04 Why quantum energy matters for health ... 00:30:45 Research findings: ATP and wound healing via quantum entanglement ... 00:32:06 Clarifying the mechanism: reducing energetic stress ... 00:36:16 Our Amazing Sponsors: Bioregulators by Nature's Marvels - targeted peptides designed to support cellular signaling and renewal across key systems like circadian rhythm, immune function, and vascular health as part of a foundational longevity stack; head to www.profound-health.com/?Aff=Longevity15  and use code NAT15 for 15% off your first order. Tro Zzz by Troscriptions – A fast-acting sleep troche that dissolves in your cheek and combines melatonin with compounds like honokiol, adenosine, cordycepin, CBD, CBN, and 5-HTP to support deep, restorative sleep when travel, stress, or late workouts throw things off. Head to troscriptions.com and use code NAT10 for 10% off your first order. Vampire Exosome by Young Goose - A next-generation serum packed with three trillion PRP-derived exosomes and RejuvNAD to support collagen production and skin renewal at the cellular level—helping results build over time instead of fading fast. Shop at younggoose.com and use code NAT10. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Dr. Bill Lawrence Episode

Preventing Injury, Reframing Pain, and Using Physical Therapy to Avoid Unnecessary Surgery: Dr. Tom Walters is a board-certified orthopedic physical therapist, founder of Rehab Science, and author of “Rehab Science: How to Overcome Pain and Heal From Injury,” an illustrated, body-region guide to common orthopedic problems and self-managed therapeutic exercises. Walters emphasizes using PT-style mobility and resistance training preventively to increase tissue capacity, manage load, and avoid overuse injuries, while warning against “no pain, no gain” and excessive volume or weight. He discusses “movement literacy,” hip and glute stabilizers, and how weakness can drive knee and back problems. Dr. Hoffman shares his own hip injury and recovery with targeted strengthening, illustrating that imaging findings often don't dictate function. Walters explains the biopsychosocial model of pain, graded exposure, the limits of RICE and ultrasound, and roles for manual therapy, taping, TENS, shockwave, acupuncture/dry needling, and PRP. They advocate prehab/rehab around surgery and note PT training and career prospects.

Episode 200: Pet Shop Boys – Please (1986) (Featuring Andrew Dineley of "Art on Your Sleeve") – Part 1 and Colours of Ever announcement The 200th "regular" episode of Permanent Record Podcast is here! ("Regular" excludes special episodes and the PRP 007 Mini-Broadcasts, which don't follow the same numbering scheme.)   Brian and Sarah wanted to do something big and special for episode 200, so they chose to cover an album which recently celebrated its 40th anniversary: Please, the debut album from the Pet Shop Boys. And to make the episode even bigger and more special, they invited the charming and talented Andrew Dineley to join in on the conversation. Andrew, as you probably already know, is host of the excellent "Art on Your Sleeve" podcast, as well as proprietor of the fabulous Soft Octopus Design Studio and contributor to Classic Pop magazine. This first episode in the Please series sets the stage for what's to come. Brian and Sarah look back to the pre-Pet Shop Boys days of Neil Tennant and Chris Lowe and recount the story Neil and Chris's first meeting. Our hosts then follow the journey of the Boys' musical collaboration, which takes us from Chelsea, to Camden Town, to New York City, and back to London, and introduces us to characters such as Ray Roberts, Bobby Orlando, Tom Watkins, and Stephen Hague.  Andrew Dineley joins the conversation to provide insight on the design aspects of Please such as the original album cover concept, the final cover design done by Mark Farrow, as well as a few of the single covers. He also shares stories about and from Pet Shop Boys' first manager, Tom Watkins, and Andrew recalls his first exposure to Pet Shop Boys music-- on a children's show with eerily-animated pound notes! And, we even get to hear about a chance encounter recently Andrew Dineley had with OMD's Andy McCluskey! As is usual with PRP album discussions, the release history, chart positions, and reviews of Please are covered in this episode, as well as Brian and Sarah's personal history with the album, which Brian feels slightly embarrassed to share.  And because it's the big 200th episode, several listeners sent in voicemails to mark the occasion, and our hosts happily share those messages as well.  Finally, as if that's not enough, Brian has exciting musical news of his own to share, about yet another synthpop duo. This duo, called Colours of Ever, consists of Brian and his longtime friend Jason, and they've released their first single on Bandcamp! Check them out at https://coloursofever.bandcamp.com/ . There's so much good stuff in this episode, so don't delay-- Please download and listen to it today! Video discussed in this episode: Pet Shop Boys performing "Opportunities" on Poparound, July 1985 https://youtu.be/rVxqEWt4Inc?si=XY6kZ9MHay9IwUUj Listen to Andrew on his "Art of Your Sleeve" podcast: https://softoctopus.co.uk/podcast/ Get all the details on Andrew's design studio: https://softoctopus.co.uk/ Read more at http://www.permanentrecordpodcast.com/ Visit us at https://www.facebook.com/permrecordpodcast You can also find us on Threads: https://www.threads.net/@permanentrecordpodcast Check out some pictures at https://www.instagram.com/permanentrecordpodcast/ Join the ever-growing crowd on BlueSky: https://bsky.app/profile/permrecordpod.bsky.social Leave a voicemail for Brian & Sarah at (724) 490-8324 or https://www.speakpipe.com/PermRecordPod  - we're ready to believe you!

Join us in this episode as we explore the cutting edge of regenerative medicine, longevity, and non-surgical recovery with Dr. Jeff Gross. As a board-certified, fellowship-trained neurosurgeon and founder of ReCELLebrate, Dr. Gross brings decades of clinical experience helping patients address athletic injuries, spinal degeneration, joint pain, and age-related decline using advanced biologic therapies. With published research cited more than 1,000 times, numerous medical book chapters, and international recognition as a speaker, Dr. Gross offers a grounded perspective on where regenerative care is today, and where it may be headed next… This conversation covers: Where stem cell therapy may offer the greatest benefits. The various applications of regenerative therapies. The best way to administer exosomes.  What PRP therapy is, and how doctors are using it.  Tune in to hear how stem cells, PRP, peptides, and other emerging therapies are reshaping the future of healing and performance! Follow Dr. Gross and his work on Instagram @ifixspines.

Dr. Natalie Crawford, board-certified OB-GYN and REI, answers your fertility questions. I've been on the progesterone-only pill for three years due to other medical concerns, and I recently stopped taking it because my husband and I are ready to start trying to conceive. What should I expect when coming off this type of pill? Are there any body changes to look out for, and how long does it typically take for cycles to regulate after stopping? My husband and I have been trying to conceive for a year. I'm 30 and he's 32. He was diagnosed with a varicocele, and his only borderline parameter is motility at 36%. I've been diagnosed with mild PCOS and had an HSG that suggested possible adhesions in one tube. Our fertility doctor recommended holding off on varicocele surgery and starting a medicated cycle. In cases like this, is surgery worth pursuing, or are treatments like medicated cycles or IUI typically sufficient? I'm 38, have been trying to conceive for nearly two years, and have mild PCOS with regular cycles. I've had two chemical pregnancies and recently moved forward with IVF with PGT-A. I'm currently in the two-week wait after transfer but am experiencing brown spotting again during the luteal phase. With normal labs and no structural issues, what could be causing this recurring spotting? I'm 33 with a history of severe endometriosis and large fibroids. I've had surgery that resulted in the loss of one ovary and tube. My AMH is 0.38, and there may be tubal blockage, though I haven't had an HSG yet. I also froze eggs five years ago. How do you approach decision-making between continuing to try naturally, completing further testing, or moving directly to IVF in a case like mine? I'm 43 and hoping to have a child through IVF. I have regular cycles, a history of miscarriage, ovarian cysts, and fibroids—one of which protrudes into the uterine cavity. My doctor has recommended laparoscopic surgery with a six-month recovery. Would you recommend pursuing egg retrieval and fertilization before surgery? And what are your thoughts on PRP for ovarian or uterine rejuvenation after surgery? Pre-order Dr. Crawford's debut book, The Fertility Formula, now!https://www.nataliecrawfordmd.com/book Want your questions answered on the next episode? Ask them here!https://www.nataliecrawfordmd.com/qa-submissions Learn more about your ad choices. Visit megaphone.fm/adchoices