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9 episodes with 'changes
2 episodes with 'changes
2 episodes with 'changes
3 episodes with 'changes
2 episodes with 'changes
2 episodes with 'changes
A flash-fiction podcast where a handful of writers create an original story with a limited wordcount in a limited amount of time. In this episode we put a hat on a hat and write sequels to each other's stories. The stories are: 'Changes' by Amelia Armande, a sequel to 'Raising a Child' by Joshua Crisp. 'Breathless' by Joshua Crisp, an homage to 'At the Office of the Second Specialist' by Paul Davies. 'And Her Decree' by Paul Davies, a sequel to 'The Consultation' by Ella Brasington. 'Amazon Cinematic Universe Episode Two: Echoes Rising' by Ella Brasington, a sequel to 'Amazon Cinematic Universe Episode One: Alexa Origins' by Tom McNally. 'The Moebius Marble Marvel of Monkwearmouth Glassworks' by Tom McNally, a sequel to 'Marble Run,' by Amelia Armande. Featuring listener submission: 'His Human's Muzzle' by Christopher T. Dubrowski Visit us on our website, on Instagram, or by mailing us on 100words@redbuttonaudio.org Created by Tom McNally, featuring Amelia Armande, Joshua Crisp, Paul Davies and Ella Brasington. Transcript and all story iterations are available here. Theme tune is Music For Jellyfish by Bell Lungs. Story music is by John Bartmann, released under a CC-BY license, featuring: Dungeon of Fear Sunlight Meditation Pure Consciousness Bad News Endless Seascape Submerged Music for 'Raising a Child,' 'The Amazon Cinematic Universe,' and 'At the office of the second specialist' was generated by the now-defunct Computoser. Rest in Peace, Computoser. Your strange auto-generated MIDI ditties were too beautiful for a world as cruel as this. Track art generated by Bing. Support 100 Words of Astounding Beauty through our Ko-Fi.
SEASON 11 FINALE!!! We know how crucial this presidential election is. I mean in the last I would say 20 years, this may be ranked a little higher than 2008 election for Obama. We knew we wanted to see a Black President, even though Tupac said in 'Changes', we weren't ready. Having experienced, natural disasters, scandals, and reform, it's more than time for me to emphasize how crucial voting is. I am not saying just for this election, but county, distract, and state officials all play a role in how this election can go. We the people is our motto, but if the people to speak up and act up civilly, then how far back in time will our jurisdictions go? Tap in...let's get real!
Richie Porte joins Mike Tomalaris and Christophe Mallet to discuss the year that was, his podium finish at the Tour de France, Australian cycling and what we can expect from him at Team Ineos in 2021.
Wednesday morning's briefing from The Celtic Way. Subscribe to the website here ➡️ www.celticway.co.uk/subscribe
John Lannon, chief executive of Dorás reacts to proposals to place a cap on the length of time refugees would be provided with accommodation from the Irish state.
IQ Musique feat. Ed Ramsey - Days Like This,Benji Candalerio - Just Say The Word (feat. Tamira Sanders),Mark Lower & Birdee - History (Our Love Is).Gordie - I Need Elevation (HouseWerQ Mix),Tyrone Williams - 2 Uva Kind,Mark Lewis - Love Story (Mark Lewis Flow Culture Vocal Remix),Mikki Afflick, Marlon D - Darién Gap (Main Mix),Kulakingz feat. Pepper Mashay - Gotta Find (Wade Teo Stripped Back Edit),Castaman & Luca Vanelli & Mario Percali - Better Place (Club Mix),Mark Knight/Sgt Slick/Beverley Knight - I Wanna Be Your Lover (Extended Mix),Sonic Soul Orchestra/Phillip Ramirez - Happy People (feat. Phillip Ramirez) (Jay Vegas Classic Disco Mix),Derrick McKenzie & Angela Johnson - On My Way Out (Radio Edit),Portia Monique - Grace (Sir LSG & The Bless Remix Edit),King Bee - Good To Be Back (feat. Andre Espeut),Ciyo Brown - The Borderline (Remix),Karlos Edwards feat. Everett Peters - Summer Soft,Anthony David & Algebra Blessett - Heaven (Amapiano Mix Edit),Robert Imtume Owens - Elementary (Radio Version),Output/Input - Doin' Alright (feat. O'Bryan)(from 'Forward Motion'),Paulette McWilliams - New Tunes Old Grooves,(from 'These Are The Sweet Things'),Mike Lindup - Atlantia (from 'Changes 2'),Candace Woodson - Perfect (Nigel Lowis Re-Mix),Marilyn McCoo - Shine On Silver Moon (12" Mix),
En esta edición estrenamos 'Changes 2', el nuevo disco en solitario del compositor, teclista y cantante Mike Lindup, uno de los componentes de la exitosa banda Level 42. Repasamos novedades de la música Smooth Jazz protagonizadas por Stephen Duros, Lin Rountree, Brian Bromberg, Cindy Bradley y Everett B Walters. En los minutos para el recuerdo repasamos algunos de los momentos más destacados de la discografía del bajista Michael Manson.
A show where Jakey called in to premiere his new single plus Petti Hendrix co-hosted and Riley came by to co-host and premiere 3 new songs off his EP that just dropped 'Changes' The post Jakey, Co-hosts Petti Hendrix and Riley appeared first on idobi Network.
Inflation has remained stubbornly high in the UK, presenting problems for multi-asset investors - particularly those seeking an income.This week FTAdviser's David Thorpe is joined by Charlie Parker, managing director at Albemarle Street Partners, Eugene Philalithis, head of multi-asset investments for Europe at Fidelity, and Alex Crooke, who runs the Bankers investment trust at Janus Henderson.They discuss how inflation changes the calculation for multi-asset investors, the balance of seeking an income versus seeking capital growth at a time of inflation and the role of sector risk in investment decisions.The FTAdviser Podcast is the podcast for financial advisers, brought to you by FTAdviser. Each week, FTAdviser is joined by guests fro the industry to discuss the week in news and pressing industry issues. Hosted on Acast. See acast.com/privacy for more information.
Welcome back to 'Dem Vinyl Boyz,' the podcast that delves into iconic albums and influential artists in the music world. In this follow-up episode, we continue our exploration of one of the most pivotal albums in rap history: 'All Eyez on Me' by Tupac Shakur. In our previous episode, we dissected the first disc of this double-disc masterpiece, unraveling the profound impact of songs like 'California Love' featuring Dr. Dre and the thought-provoking 'Changes.' Now, in Part Two, we dive deep into the tracks that defined the second disc of 'All Eyez on Me,' revealing even more layers of Tupac's artistry. Join us as we analyze tracks such as the emotionally charged 'Dear Mama,' a heartfelt tribute to Tupac's mother that showcases his vulnerability and ability to convey raw emotions through his music. We'll explore the intricate storytelling, the powerful lyrics, and the universal resonance of this deeply personal anthem. Moving forward, we'll delve into the politically charged 'I Ain't Mad at Cha,' a track that touches on themes of betrayal, redemption, and the harsh realities of life. With its introspective tone and Tupac's introspective lyrics, this song exemplifies his ability to tackle complex subjects with honesty and insight. Additionally, we'll explore tracks like 'Ambitionz Az a Ridah' and 'Only God Can Judge Me,' which highlight Tupac's unapologetic attitude, lyrical prowess, and uncompromising spirit. Through these powerful tracks, Tupac solidifies his place as a rap icon, unafraid to confront societal issues head-on and demand justice for the voiceless. But 'All Eyez on Me' is more than just its individual tracks. We'll also discuss the album's production, delving into the creative process behind its rich soundscapes and the collaborations that contributed to its sonic brilliance. From the masterful production of Dr. Dre and Johnny J to the guest appearances by Snoop Dogg, Nate Dogg, and many others, we'll unveil the intricacies that make this album a timeless masterpiece. Furthermore, we'll examine the lasting impact of 'All Eyez on Me' on subsequent rap artists and the music industry as a whole. Tupac's unapologetic approach, lyrical prowess, and ability to address societal issues head-on continue to inspire artists to this day, leaving an enduring legacy that transcends generations. Join us as 'Dem Vinyl Boyz' takes you on an enlightening journey through the depths of the second disc of 'All Eyez on Me Learn more about your ad choices. Visit megaphone.fm/adchoices
Welcome to 'Dem Vinyl Boyz,' the podcast that takes you on a journey through iconic albums and influential artists in the music world. In this episode, we dive deep into one of the most pivotal albums in rap history: 'All Eyez on Me' by Tupac Shakur. Released in 1996, 'All Eyez on Me' marked a defining moment in Tupac's career and the rap industry as a whole. This double-disc album, which we'll review in two parts, showcases Tupac's raw talent, lyricism, and unapologetic attitude towards societal issues. With its mix of intense storytelling, political commentary, and party anthems, 'All Eyez on Me' quickly became a cultural phenomenon. But who exactly was Tupac Shakur? Join us as we explore the life and artistry of this influential figure, who holds the distinction of being the first artist we've reviewed twice. Tupac was more than just a rapper; he was a poet, an actor, and a passionate advocate for social justice. Around the time of 'All Eyez on Me's' release, Tupac was a rising star, already hailed as a voice for the voiceless. He used his platform to shed light on the struggles faced by marginalized communities and to expose the flaws in the system. From his confrontational public persona to his deeply introspective tracks, Tupac's charisma and authenticity resonated with millions around the globe. In this episode, we'll delve into the tracks that defined 'All Eyez on Me,' including the iconic 'California Love' featuring Dr. Dre, the thought-provoking 'Changes,' and the emotionally charged 'Dear Mama.' Additionally, we'll analyze the album's production, its influence on subsequent rap artists, and its enduring legacy in the music industry. So grab your headphones and join us for an insightful discussion as 'Dem Vinyl Boyz' unravel the layers of 'All Eyez on Me' and explore the impact of Tupac Shakur, an artist who left an indelible mark on both rap culture and society at large. Learn more about your ad choices. Visit megaphone.fm/adchoices
China's President Xi Jinping traveled to Russia to meet Vladimir Putin, where they pledged "changes the likes of which we haven't seen for 100 years", agreeing to deepen economic integration and challenge the hegemony of the US dollar by promoting the use of the yuan and other currencies in international trade. VIDEO: https://youtube.com/watch?v=OddmSjjLgLY BRICS challenges US ‘dollar dominance', Saudi considers selling oil in other currencies: https://geopoliticaleconomy.com/2023/01/21/brics-us-dollar-saudi-oil-currency-multipolar/ Geopolitical game changer: China's Iran-Saudi peace deal is big blow to petrodollar and US economic hegemony: https://geopoliticaleconomy.com/2023/03/17/china-iran-saudi-peace-petrodollar Ukraine's Zelensky admits he sabotaged Minsk peace deal with Russia, West blocked negotiations: https://geopoliticaleconomy.com/2023/02/10/ukraine-zelensky-minsk-peace-russia
Jeremih joins TT Torrez and talks his new single 'Changes', taking a 7 year hiatus, his longterm battle with COVID-19, developing a new sound, looking for love and also new music! Tap In With TT is a podcast where TT Torrez interviews the biggest names in hip-hop. TT is a Multi-Media Personality, the Vice President of Artist and Label Relations, as well as the Music Director for HOT 97 - making her one of the most well-connected women in music! Her unique interview styles brings out the personal side of many of your favorite artists.See omnystudio.com/listener for privacy information.
JCO PO author Dr. Mark Stewart, PhD, Vice President, Science Policy at Friends of Cancer Research, shares analysis on clinical trials and the association between CT-DNA and outcomes in lung cancer. Host Dr. Rafeh Naqash and Dr. Stewart discuss dataset metrics, identification of biomarkers, timepoints, and checkpoint inhibitors, development of new medicines, and novel technologies measuring CT-DNA. Click here to read the article! TRANSCRIPT Dr. Rafeh Naqash: Welcome to ASCO's JCO Precision Oncology Conversations, where we bring you highlights and overview of precision oncology. Episodes will feature engaging conversations with authors of clinically relevant and highly significant articles published in JCO Precision Oncology. These articles can be accessed at: ascopubs.org/journal/po. Hi, I'm Dr. Rafeh Naqash, Medical Oncologist, and Assistant Professor of Medicine at the OU Stephenson Cancer Center, and you're listening to JCO Precision Oncology Conversations podcast. Today, I am delighted to be talking with Dr. Mark Stewart, Vice President Science Policy at Friends of Cancer Research. We'll be talking about their group's recent paper in JCOPO, titled, 'Changes in Circulating Tumor DNA Reflect Clinical Benefit Across Multiple Studies of Patients With Non-Small-Cell Lung Cancer Treated With Immune Checkpoint Inhibitors'. At the time of this recording, my guest and I have no relevant disclosures. Welcome to the podcast, Mark. Dr. Mark Stewart: Thanks. Thanks so much for having me here. Dr. Rafeh Naqash: I am excited to discuss this new publication that your group has come out with, and I see this is a significant effort involving both academia and industry, and also your organization. Could you tell us about what led to this work, and then we can go into finer details about what your findings were? Dr. Mark Stewart: Sure. I might start with just briefly describing our organization. We are a non-profit patient advocacy organization in Washington, DC. And our mission as an organization is really to help accelerate development and access to new medicines. And we do this by doing horizon scanning to see kind of what issues, or emerging technologies, are coming down the pipe that might have implications in oncology. And we bring together experts from universities, government, industry, patient advocacy, to help develop evidence-based policies that can pave the way for future discoveries, but also accelerate the pace of scientific progress. I think that's really embodied in the manuscript that we recently published, and that we'll be talking about today. Dr. Rafeh Naqash: Awesome. And I have come across some of the other phenomenal work that your organization is doing, and this is definitely a step forward in developing more personalized therapies, and trying to identify relevant biomarkers so that we can treat patients and their cancers appropriately. Moving forward, could you tell us some of the main findings from this publication, and then we'll take a deeper dive in trying to understand the kind of data that you used and the kind of analysis that was done? But just as an overview for our listeners, could you briefly explain some of the major findings from this publication? Dr. Mark Stewart: Sure. Maybe in my last answer, I could have provided some rationale in terms of what led us to even initiate this project. So, I think if you look at trends in oncology drug development over the past decade, the use of precision medicines led to really incredible outcomes for patients. I think that's led to really transformative medicines. And with these therapies, if you look at the drug development paradigm, they've often used these expedited development programs at the agency, and that's largely driven by our improved understanding of the biology of the cancer, and the natural history of the disease, and the ability to use endpoints that can read out earlier, that provide us insights into whether a drug is working or not. And as we continue to improve the available treatments that patients have, we're seeing the shift where drugs are starting to be investigated in patients that have earlier disease. And because of that, the length of time it takes to understand whether a drug is working or not can often take much longer because of the follow-up time needed to read out endpoints like progression-free survival, or overall survival. And so, the ability to identify new novel biomarkers that can help us understand whether a drug is working or not sooner would certainly provide a lot of value to drug development, it could help expedite the development of new, innovative therapies for cancer patients. And I think like everyone else, when we first saw a lot of the emerging data coming out on the role of circulating tumor DNA and its potential role in clinical research and care, I think there was a lot of excitement around the potential. And when you look at all these exploratory studies, you see a lot of potential for using ctDNA changes to signal whether a drug is working. But a lot of these initial studies were conducted independently, using different methods, different technologies for measuring ctDNA, and this really left questions about the applicability of this from a more rigorous standpoint, and how this might be applied in a regulatory setting. And so, we brought together a diverse group of scientific leaders to really design a comprehensive plan that could leverage these prior studies, and then bring them together in an effective manner to where we can increase our power, strengthen our understanding of this association that we see between changes in ctDNA and outcomes. And so, this manuscript is really a first iteration of several data readouts we have planned over the next year. This first study included five different clinical trials of patients with lung cancer that were treated with immune checkpoint inhibitors. And I think one of the figures that I think is most interesting to see in this, is actually our FIG 1., where it's a swimmer plot, where it really shows the differences across all these different trials, and it also exemplifies some of the challenges that we had to overcome when we brought all these datasets together, but yet still arrive at some meaningful data to address our core question of whether changes in ctDNA can predict treatment outcomes. Dr. Rafeh Naqash: So, definitely an exciting endeavor that you guys have brought forward this aspect of ctDNA. So, in my other life I'm involved in a lot of early-phase clinical trials, and my patients often ask me, "How is it that you're going to assess our response? How long will we be on treatment?" And currently, as most of our listeners know, the standards are primarily using CT scans, or other imaging modalities to assess for responses, and with the innovation that's being made in the field of circulating tumor DNA, it's definitely transforming the world and innovations on the precision oncology side. For example, in GI cancers, there's been significant development, there are clinical trials in this setting. In the lung cancer setting, there are clinical trials trying to assess ctDNA-related changes, and treatment changes associated with those alterations, or decrease, or increase, in the ctDNA. So, based on what you describe here from the understanding that I have reading through this interesting paper, you used, as you mentioned, previously-conducted clinical trials. Could you tell us a little more about what kind of clinical trials were these, and for non-small cell lung cancer, and what kind of therapies patients were treated with in these clinical trials, and how did you determine which clinical trials you would use for this project? Dr. Mark Stewart: Sure. When we first launched this project, we basically put a call out to various drug developers, academic investigators, to see what types of data were even available. And at that time, maybe not a surprise to many, there was a lot of ongoing clinical trials that were measuring ctDNA in patients with lung cancer. And because of that, we found a number of clinical trials that kind of fit a general criteria that we felt could be brought together as part of this initial analysis. We tried to keep the criteria broad, we didn't want to be overly exclusive. So, we didn't limit the studies to having to have used a specific assay, for instance, and we thought that that was an important component here because we wanted to understand whether this phenomenon of changes in ctDNA being associated with outcomes isn't necessarily due to a specific technology. And I think the strength of this becoming a potential endpoint is that it is something that can be reproducible and repeated regardless of the kind of technology that was used. The clinical trials, it's also important that they had multiple timepoint collections while the patient was on treatment because there's still questions remaining around what's the right time to collect ctDNA, and which timepoints are most correlative to long term outcomes. And we thought those were important things to begin to investigate in our study. And so, it was really the availability of data that naturally led us to first starting in lung cancer. Dr. Rafeh Naqash: Sure. Thank you for that explanation, Mark. And to the best of my understanding, when I read through some of the details in the manuscript, there's a mention that these were five clinical trials. Patients had been treated with either immunotherapy alone, or immunotherapy with chemotherapy, both being the standards of care, depending on some of the other biomarkers and disease burden. But from a ctDNA perspective, it seems that you were trying to include mostly patients that had at least two assessments done at baseline, no earlier than 14 days, and at least one within the first 70 days of treatment initiation. Is that a fair understanding from what has been described in the manuscript? Dr. Mark Stewart: Yes. And we didn't limit as well to a specific immune checkpoint inhibitor. Again, for us, our goal was to cast a broad net and try and include as many clinical trials as we could in this first analysis. Dr. Rafeh Naqash: Right. And I guess, based on the data that you have used in this project, there's obviously heterogeneity with the trials, with the treatment, with probably different lines of therapies that the patients had been treated with, so, that is probably why you were trying to explore different metrics of this ctDNA change. And there's a couple of metrics, it seems, that you and your team have assessed here; one of the metrics that seemed to stand out was this metric where you used three different categories of patients that, depending on the change in the ctDNA, whether they had a decrease, an intermediate category, and a category that had an increase. So, Mark, based on the findings on the paper, it seems that you're using different ctDNA-based metrics to assess changes in responses and survival. Based on the methodology, what was the most appropriate, or the strongest one that you were able to identify that was associated with differences in survival, and responses as you've sort of explained in the manuscript? Could you describe that briefly for us? Dr. Mark Stewart: When initiating the study, there were a lot of unknowns in terms of how we would be able to bring together these different datasets, particularly knowing that they use different ctDNA assays that potentially included targeted panels, and whole genome sequencing, and also had different kind of readouts and metrics that were used. And so, early on we explored various metrics. And the one that rose to the top was a variant allele frequency, which is simply the number of mutant alleles divided by the total number of mutant and wall-type alleles. And there's different ways you can report that out -- it could be a mean, it could be a median, or a maximum. While we didn't necessarily see large differences between those, we did observe that consistently, maximum VAF correlated with overall survival and was one that we continued to use as a primary analysis in our manuscript. Dr. Rafeh Naqash: So, Mark, based on some of the analysis you've done here, was a landmark timepoint used to compare survival for the patients because there could be a difference in the number of timepoints of ctDNA assessment for different patients, which would, in turn, mean that some patients could have been treated longer versus some other patients? So, did you try to limit that heterogeneity by performing a landmark analysis on this cohort? Dr. Mark Stewart: Yes. That was one of the approaches we had to take, given the heterogeneity across the different studies that we included in this analysis. In FIG 2., again, you can see across the five different studies how there are different numbers of ctDNA timepoint collections, but also that they were collected at different timepoints. And so, to try and create a more equal playing field and informative analysis here, we did use a landmark of 70 days here and used ctDNA timepoints that were around that landmark when we were looking at the association between changes at that particular time to overall survival, or progression-free survival. Dr. Rafeh Naqash: So, Mark, based on what you've shown here as far as overall survival is concerned, could you tell us about how the specific ctDNA metric that you used was able to compartmentalize patient survival on checkpoint inhibitors? Dr. Mark Stewart: Sure. As I'd mentioned previously, in this analysis, we used a three-level variable to differentiate response to treatment using ctDNA. This three-level ctDNA metric represented patients that had a decrease in ctDNA from baseline, an intermediate change, or an increase. And so, for each of these three ctDNA metrics, we were able to bucket patients into these three categories based on the percent change and varying allele frequency. And so, those that had the 50% decrease in ctDNA were bucketed in the 'decrease' category, and those that had a 50% change in the positive direction were bucketed in the 'increase', and then all the patients that remained were placed into the 'intermediate' category. And as you can see from the Kaplan-Meier Curves, I think a quite robust differentiation between those three groups. Dr. Rafeh Naqash: Right. And another interesting finding on one of the forest plots that you've shown is that patients who smoked had a better survival or better outcome with therapies. And I remember a couple of years back reading an interesting paper in Science, if I remember correctly, from a group at Sloan Kettering, showing the increased neoantigens and mutational burden related to smoking, that probably predicts better responses. Is there any other interesting aspect to this from a ctDNA standpoint that your group was able to identify, or is looking at, at least in this comparison of smokers versus never-smokers? Dr. Mark Stewart: Yeah. Actually, when we took into account all the different clinical variables that were included in these datasets, we actually saw an association between patients that were smokers or had smoked at one point, and the ctDNA levels that were present. Despite that smoking may impact the levels of ctDNA present, I think, the fact though, that we are trying to determine whether a treatment is working, or not, based on a change, or a delta, between a baseline and a subsequent timepoint, it shouldn't really matter necessarily what your baseline is, so long as you're still able to observe a decrease or an increase. Dr. Rafeh Naqash: From, I guess a futuristic perspective since this project primarily involved pooling of data from five different clinical trials, is there a plan to validate some of this in an independent cohort of patients in the next year to two years? Dr. Mark Stewart: Yes. As I mentioned, the CT Monitor project that we've developed into multiple different modules, and the modules have been broken up basically in terms of when data is available in different clinical trials. And so, we've continued to work with different drug sponsors and academic investigators to put together data use agreements, and I'm excited to say that we have three different modules that we plan to read out over the course of this next year. We have a module that includes patients with lung cancer that are treated with a TKI - Tyrosine Kinase Inhibitor. We have a second module that is an additional analysis in patients with lung cancer treated with immune checkpoint inhibitors. I think a key thing to highlight there is that the studies that we'll include in this next round are all randomized clinical trials, and so, we'll be able to look at the ability to differentiate between two treatments using ctDNA, and understanding its kind of predictive nature as a potential endpoint. And then the third module is really kind of a catch-all that includes multiple different cancer types, and where patients have been treated with either a Tyrosine Kinase Inhibitor or an immune checkpoint inhibitor. And across all of those studies, we have about 22 different clinical trials that'll be included in those analyses that represent over 3000 patients. And so, I do think we'll be able to validate the findings that we've been able to show in this latest publication, and also address some additional questions. Many of these studies are newer, so I think people have learned from some of the earlier clinical trials that included ctDNA. So, in these latest studies you see many more collection timepoints. You also see earlier collection timepoints even before the first RECIST measurement. So, I think we'll be able to understand, again, get greater granularity on, what are the optimal timepoints for collecting ctDNA; how early can ctDNA predict clinical outcomes; and finally, just to add to that body of evidence that can hopefully help provide confidence to the community that this is an objective and meaningful measure, and that could hopefully be used in a regulatory standpoint as a potential early endpoint that could serve as a basis for a drug approval. Dr. Rafeh Naqash: Those are all awesome, phenomenal things that need to be accomplished, definitely, and your organization is leading these efforts in a one-of-a-kind public-private partnership. And I completely agree with you that this could be a very important biomarker metric for patients who are treated with novel therapies, including checkpoint therapies, Tyrosine Kinase Inhibitors, or even potentially, on clinical trials. From a practical application standpoint, Mark, has your organization also made any efforts in terms of trying to see how we can try to get both FDA and insurance approval for patients who are treated on standard of care therapies but would benefit from having serial, you know, every four to six months ctDNAs done? Because I try to do that sometimes in my practice and do face occasional challenges from insurance companies where they're not willing to pay for repeated ctDNA assessment. And I try to space it out when I'm not getting CT scans, you know, alternate it with CT scans. But is there any kind of an effort in that direction where from a regulatory standpoint, in the next one to two years, we can make progress so that clinicians are able to order ctDNA on patients, whether they're treated on checkpoint therapies or other targeted therapies? Dr. Mark Stewart: That's a critical issue that you raise, and certainly a potential barrier that can prevent patients from benefiting from this novel technology. To date, our efforts have been mostly focused in kind of the use of ctDNA in the research space, but I think that they're not mutually exclusive. I think one important way to ultimately get coverage for these tests is to have that evidence base that really shows the utility that it is providing benefit to patients. I look at this as kind of a first step to getting there, and I think once you have this evidence, and also you have the right evidence that we know payers want to see, that hopefully, it can help address those potential concerns. Dr. Rafeh Naqash: I could not agree with you more. And your work, definitely, is a step forward in the right direction, and I think will lead to a lot of exciting subsequent things, as you mentioned. I congratulate you and your group again, on this exciting project, and I appreciate that you chose JCO Precision Oncology as the final destination for this phenomenal work. Dr. Mark Stewart: Thank you for having me. And certainly I just want to extend gratitude to my fellow authors. I think we have around 34 authors on this manuscript, and I think it just, demonstrates the recognition that this truly does require collaboration across different stakeholders, and look forward to next steps. Dr. Rafeh Naqash: Thank you so much, Mark. Thank you for listening to JCO Precision Oncology Conversations. You can find all our shows, including this one, at: asco.org/podcasts, or wherever you get your podcasts. To stay up-to-date, be sure to follow and share JCOPO content on Twitter with the handle: @JCOPO_ASCO. All JCOPO articles and series can be found at: ascopubs.org/journal/po. The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy, should not be construed as an ASCO endorsement. Guest Bio Mark D. Stewart, PhD, is Vice President, Science Policy at Friends of Cancer Research in Washington, DC, an advocacy organization that drives collaboration among partners from every healthcare sector to power advances in science, policy, and regulation that speed life-saving treatments to patients.
Musician, Jeremih joins ladies of Lip Service this week to promote his new single 'Changes.' Jeremih opens up about his time in the hospital with COVID, why his name is Jeremih & Thumpy Johnson, being set up on Love and Hip Hop, and much more. Enjoy! Also sending a major thank you to Swaggy Sie and Jasmine Brand for guest hosting with us! Make sure to get your Lip Service merchandise at www.aylipservicemerch.com See omnystudio.com/listener for privacy information.
The Locked On Cougars Podcast for Wednesday, October 19, 2022 The BYU Cougars are in full preparation mode for their road game against the Liberty Flames, but all anyone wants to talk about are the much-rumored and reported "changes" going on with the defensive staff and Jake Hatch has some thoughts on what's going on Jake then talked further about his observations from Tuesday's practice, including injury updates on BYU's running back room, Gunner Romney, schemes for the Cougars as they head cross-country to Lynchburg, VA and more Finally, the show wrapped up with some shoutouts to longtime and loyal listeners as well as a tribute to a Cougar fan taken too soon Support Us By Supporting Our Locked On Podcast Network Sponsors! LinkedIn - LinkedIn jobs helps you find the candidates you want to talk to, faster. Post your job for free at Linkedin.com/LockedOnCollege. Terms and conditions apply Built Bar - Built Bar is a protein bar that tastes like a candy bar. Go to BuiltBar.com and use promo code “LOCKEDON15,” and you'll get 15% off your next order Upside - Today's episode is brought to you by Upside. Download the FREE Upside App and use promo code Locked to get $5 or more cash back on your first purchase of $10 or more Underdog - Today's episode is brought to you by Underdog. Sign up on underdogfantasy.com with the promo code LOCKED ON and get your first deposit doubled up to $100! SimpliSafe - Today's episode of Locked On Cougars is sponsored by SimpliSafe Home Security. With Fast Protect™️ Technology, exclusively from SimpliSafe, 24/7 monitoring agents capture evidence to accurately verify a threat for faster police response. There's No Safe Like SimpliSafe. Visit SimpliSafe dot com slash LockedOnCollege to learn more. Follow the Locked On Cougars podcast on Facebook, Instagram and Twitter to stay up-to-date with the latest with regards to the podcast and BYU sports news. Please remember to subscribe, rate and review the show. Also, please consider subscribing to the Yawk Talk Newsletter that Jake writes and is delivered directly to your email inbox. If you are interested in advertising with Locked On Cougars or the Locked On Podcast Network, please email us at LockedOnBYU@gmail.com or contact us here. Learn more about your ad choices. Visit podcastchoices.com/adchoices
On this weeks programme John and Shane take a run around the world to look at events happening. News from around the worldPope Francis visit to Canada on a penitential pilgrimage - good summary from CNS here as to why the pope is in Canada. The Pillar has analysis here.Pope Francis has made College of Cardinals ‘less European,' analysis showsWill Pope Francis resign? - Pope: ‘If I resign one day, I'll hear confessions and visit the sick'Changes to organisation of Opus DeiPersecution of Christians in Nigeria - refer to Pillar coverage HERE.In the first three months of 2022, 896 Nigerians were murdered in violent attacks across their country.......In the last couple of months the abduction of priests have been on the rise:A priest of Auchi Diocese, Fr. Christopher Odia, was killed by his abductors after being kidnapped early in the morning on June 26; the priest was taken from his rectory.A priest of Kaduna Archdiocese, Fr. Vitus Borogo, was shot June 25 at a prison-farm in Kujama, along Kaduna-Kachia road, after a raid on the farm by terrorists.On March 8, gunmen invaded St. John Catholic Church, Kudenda, in the Chikun Local Government Area. They abducted the priest, Fr. Joseph Akete, and killed one security guard. The 48-year old priest was murdered between April 18 and 20, 2022.Fr. Emmanuel Silas, a priest of the Kafanchan diocese, in Nigeria's northwest, was kidnapped in the early hours of July 4, just this week. Fr. Peter Udo and Fr. Philemon Oboh were kidnapped July 2; their car was attacked as they traveled on the Benin-Ekpoma expressway.Fr. Stephen Ojapa, Fr. Oliver Okpara, along with a pair of siblings, were abducted by gunmen at midnight on May 25, in the rectory of St. Patrick's Catholic Church, in the Sokoto diocese in northwest Nigeria. They were released after more than 30 days in captivity. Fr. Christopher Itopa, pastor of Our Lady of Perpetual Help Church, Onotu, was abducted on June 4, and was eventually freed.On June 3, an expatriate priest, Fr. Luigi Brenna, was kidnapped in front of the Somascan community residence in Usen. He was later set free. Fr. Peter Amodu, a priest of the Holy Ghost Congregation - a Spiritan- was abducted June 6 along the Otukpo - Ugbokolo road in the Otukpo diocese
On this weeks programme John and Shane take a run around the world to look at events happening. We also have our liturgical odds and ends for this week including saints of the week for the 18th week in ordinary time (Psalter Week II). News from around the worldPope Francis visit to Canada on a penitential pilgrimage - good summary from CNS here as to why the pope is in Canada. The Pillar has analysis here.Pope Francis has made College of Cardinals ‘less European,' analysis showsWill Pope Francis resign? - Pope: ‘If I resign one day, I'll hear confessions and visit the sick'Changes to organisation of Opus DeiPersecution of Christians in Nigeria - refer to Pillar coverage HERE.In the first three months of 2022, 896 Nigerians were murdered in violent attacks across their country.......In the last couple of months the abduction of priests have been on the rise:A priest of Auchi Diocese, Fr. Christopher Odia, was killed by his abductors after being kidnapped early in the morning on June 26; the priest was taken from his rectory.A priest of Kaduna Archdiocese, Fr. Vitus Borogo, was shot June 25 at a prison-farm in Kujama, along Kaduna-Kachia road, after a raid on the farm by terrorists.On March 8, gunmen invaded St. John Catholic Church, Kudenda, in the Chikun Local Government Area. They abducted the priest, Fr. Joseph Akete, and killed one security guard. The 48-year old priest was murdered between April 18 and 20, 2022.Fr. Emmanuel Silas, a priest of the Kafanchan diocese, in Nigeria's northwest, was kidnapped in the early hours of July 4, just this week. Fr. Peter Udo and Fr. Philemon Oboh were kidnapped July 2; their car was attacked as they traveled on the Benin-Ekpoma expressway.Fr. Stephen Ojapa, Fr. Oliver Okpara, along with a pair of siblings, were abducted by gunmen at midnight on May 25, in the rectory of St. Patrick's Catholic Church, in the Sokoto diocese in northwest Nigeria. They were released after more than 30 days in captivity. Fr. Christopher Itopa, pastor of Our Lady of Perpetual Help Church, Onotu, was abducted on June 4, and was eventually freed.On June 3, an expatriate priest, Fr. Luigi Brenna, was kidnapped in front of the Somascan community residence in Usen. He was later set free. Fr. Peter Amodu, a priest of the Holy Ghost Congregation - a Spiritan- was abducted June 6 along the Otukpo - Ugbokolo road in the Otukpo dioceseAnnual Novena at Knock The National Novena to Our Lady of Knock will take place from Sunday 14th – Monday 22nd August, 2022. Ceremonies will take place in the Basilica at 3pm and 8pm over the course of the nine days with guest speakers present during each ceremony. We also look forward to the return of the special candlelight procession, a traditional feature of the Novena at Knock, which takes place following the 8pm ceremony (weather permitting).Full list of speakers and other information available HERE.
Uväll's 'Changes' EP represents the progression of the Tbilisi based artist's journey in music production, featuring music from different eras. Uväll's sonic is unique, a big part of what drew us to his music. 'Changes' has moods, menace and raw dance energy. The Georgian producer is a part of Tiblisi's flourishing underground scene. Uväll's music has been released on Hayes Collective and Semantica amongst others. Mastered by Fergus Sweetland. Artwork by Liam White. Graphic Design by Luke Webber. Distributed by Triple Vision. @uvallmusic
R&B music artist Dria joins this special episode as the artist of the month for the podcast! Talking about her upbringing in St. Louis, singing in church, & her love for Imo's Pizza, Dria highlights her single, 'Changes,' which can be found wherever you get your music. Follow Dria on social media @driiias.
NYC based comedian Soo Ra talks about starting comedy in Miami, moving to the East Coast, in addition to her notable appearances on BuzzFeed & Worldstar Hip Hop. Recounting stories from creating material with Fusion Comedy & dealing with hecklers, Soo Ra is force in comedy & one of a kind. Follow Soo Ra on social media @hoora4soora. Song at the end of the episode is titled 'Changes' by Dria S & can be found on all streaming services.
Comedian Gwen Sunkel returns to the podcast to discuss her comedy album, 'No More Tears,' recording it at the White Rabbit Cabaret in Indianapolis, how she bought a one story house to make it more comfortable for her pets, & celebrating her 40th birthday. 'No More Tears' is to be released in February 2022. Follow Gwen @gwenderwoman for the official release date & everything Gwen! Song at the end of the episode is titled 'Changes' by Dria S & can be found on all streaming services.
Welcome back! Please leave a rating on Spotify and Apple Podcasts! Format below 0:00 Intro 01:16 News 05:22 Changes I Want to See 12:24 Mailbag Questions Cro Socials
Tombow Mono 100 - 12 pack – Nero's NotesBlackwing Volume 33 1/3Blackwing Volume 651Halloween Kills - I'm not going to link it, it's bad.THE FRENCH DISPATCH | Official TrailerDune Official TrailerShowtrial | Trailer - BBCHugh Laurie - ''Changes''The Page One PodcastAt your Best - Carey NieuwhofThe Devil and the Dark Water - Stuart TurtonNanosphere - A different look at stationery and home workingNock Co.CW Pencil Enterprise************Neros NotesStationery Adjacent PodcastThe Three Pin Plug************1857 Merch!1857 Website1857 Twitter1857 The Podcast about making the past, the present, in the future.
After a covid- enforced year of absence, the lads are back with another season of YouthPod Ireland, where the conversations at the table are, as always, all about the young people. In this first episode of Season 07, we look at the changes that have occurred in our own lives over the last year, in the lives of young people and in the youth work sector. A long- awaited catch- up for three of the original YouthPod Ireland crew and the first of very many more to come as we continue to have those countless arguments, opinions, discussions, ideas and debates but as ever, as long as it is youth- relevant, we've got you covered. Big thanks to our silent sponsors for keeping the show on the road and to the many, many listeners, new and old who have continued to dip into our library of episodes over the past year... you've made this comeback all the more special and worthwhile. We are delighted to be back... thank you for the continued support!
All uploads on this channel are for promotional purposes only! The music has been converted before uploading to prevent ripping and to protect the artist(s) and label(s). If you don't want your content here (that goes for audio or images) please contact me immediately via email: unpluggedtube@outlook.it and I WILL REMOVE THE EPISODE OR ARTWORK IMMEDIATELY! ---------------------------------------------------------------------------------------------------- Lauv sat down at the MTV News offices to perform 'Changes,' 'Tattoos Together,' and 'Modern Loneliness' in front of a live audience. He also spoke with MTV News correspondent B. Dot and answered fan questions. 0:25 - Lauv talks about his new album 'How I'm Feeling' 0:58 - Collaborating with BTS 1:48 - Plans for future albums 2:14 - What's do you write for you and what's for the listener? 2:36 - 'Changes' performance 7:03 - 'Tattoos Together' performance 11:15 - Lauv's favorite song on 'How I'm Feeling' 11:56 - Plans for the 'Modern Loneliness' music video 13:13 - 'Modern Loneliness' performance #Lauv #OfficeHours #MTVNews Team UNPLUGGED.
When and why did we forget to take responsibility for ourselves? Or did we relinquished the responsibility to someone else? Tonight we have such questions for the P.S. Youniverse. Music credit... Charles Bradley performs soulful cover of Black Sabbath's 'Changes' Tom MacDonald - "Brainwashed" --- Send in a voice message: https://anchor.fm/ps-you-got-this/message
In her fourth episode of Series 2 Maddy takes a deep dive into: mime and silent comedy, modern comedians, the decline of sitcom and the rise of stand-up, Steptoe & Son - and her favourite comedy roles... In conversation with Bill Lawrance
Liberated from a self-destructive past and born anew in sobriety, Francis has captured an inspired collection of songs steeped in New Orleans rhythms and early 70s rock n' roll. His music evokes a bygone era of R&B's heyday while simultaneously forging a new path on the musical landscape. We chat about his past with addiction, his sobriety and how it related to his music. The journey from a hospital bed to launching his solo career was neither predictable nor straightforward. There were musical fits and starts, relapses, and broken relationships. Yet the overwhelming passion driving Francis in this second act has been an abundance of creative energy. We also talk about growing up, various day jobs, working with soul musicians on the road, and his past bands that led up to his album 'Changes' and his new record due out soon. Visit the website: https://www.bedroombeethovens.com/ Support the show on Patreon: https://www.patreon.com/bedroombeethovens
Seth Godin suggests that 'Changes in the culture often happen when someone is gutsy enough to reorganize the time stack.' We've established generally accepted time frames for things in our life. This is how long a doctor's appointment will be. This is how long a spa treatment will be. This is how long it will take to build a new house or a new car. And if you, in your business, spend about the same amount of time as everyone else is spending to do those things, you'll end up with roughly the same result. The way to stand out, says Seth, is to change the Time Stack. Maybe you spend a lot MORE TIME making your product or delivering your service. And in so doing, you can hopefully now charge more for the high quality you have created. Or, you spend LESS TIME. Get it done quickly. Then move on to other things. new innovations and ideas. Or marketing your thing to a wider market. Either is fine. But, if you want to create a significantly different value proposition, you'll probably need to choose one. #time #valueproposition #thinkdifferently
In this podcast Ulrica Jonsson discusses her paper 'Changes in walking ability, intellectual disability, and epilepsy in adults with cerebral palsy over 50 years: a population-based follow-up study'. The paper is available here: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.14871 ___ DMCN Journal: Developmental Medicine & Child Neurology (DMCN) has defined the field of paediatric neurology and childhood-onset neurodisability for over 60 years. DMCN disseminates the latest clinical research results globally to enhance the care and improve the lives of disabled children and their families. DMCN Journal - https://onlinelibrary.wiley.com/journal/14698749 ___ Watch DMCN videos on our YouTube channel: https://bit.ly/2ONCYiC
Lydia, Kalki - Liberation (Original mix) Liberation - Iboga Records http://musicshop.iboga.dk/store/view_release?release=1639 IBOGADIGITAL694 1. Lydia, Kalki - Liberation (Original mix) 2. Kalki - Changes Feat. Lydia (Original mix) A first ever collaboration from Kalki and Lydia invites listeners to discover the elegant fusion of their sounds. This emotive 2 track EP starts with the title track 'Liberation' – an absolute dance floor banger with sensual vocals by Lydia. Kalki steers the second track of the EP towards a more progressive groove with 'Changes', once again featuring contemplative words and vocals from Lydia. Quite rare to find such a well balanced blend of banging basslines, progressive melodics and emotive vocals. But Lyida and Kalki have delivered this so effortlessly. Thibault Fontaine,Lidia Pivarski 2021 Iboga Records Iboga Records Publishing,Iboga Records Publishing
Kalki - Changes Feat. Lydia (Original mix) Liberation - Iboga Records http://musicshop.iboga.dk/store/view_release?release=1639 IBOGADIGITAL694 1. Lydia, Kalki - Liberation (Original mix) 2. Kalki - Changes Feat. Lydia (Original mix) A first ever collaboration from Kalki and Lydia invites listeners to discover the elegant fusion of their sounds. This emotive 2 track EP starts with the title track 'Liberation' – an absolute dance floor banger with sensual vocals by Lydia. Kalki steers the second track of the EP towards a more progressive groove with 'Changes', once again featuring contemplative words and vocals from Lydia. Quite rare to find such a well balanced blend of banging basslines, progressive melodics and emotive vocals. But Lyida and Kalki have delivered this so effortlessly. Thibault Fontaine,Lidia Pivarski 2021 Iboga Records Iboga Records Publishing,Iboga Records Publishing
The first episode is here to explain what 'Nexus Nights' is all about.Get in contact, follow, subscribe and share on social media if you like what you hear.The Intro and Outro Music, 'The Dust Clears' and 'Changes' used are by Jim Hall on freemusicarchive.org
The first episode is here to explain what 'Nexus Nights' is all about. Get in contact, follow, subscribe and share on social media if you like what you hear. The Intro and Outro Music, 'The Dust Clears' and 'Changes' used are by Jim Hall on freemusicarchive.org
Arthur of CAPTAIN NAYSAYER and Jon chat about Canada, Callebaut, jay walking; two tracks 'Living Again', and 'Changes' the stories behind the songs, the writing process, and a sneak peak into what they have coming up! 'Living Again' https://youtu.be/LvviRUkC3dg Find out more about CAPTAIN NAYSAYER at: https://captainnaysayer.com -------------------------------------------------------------------------------------------------------------------------- Jon Harris of The Rock Metal Podcast interviews rock and metal bands to get the scoop on their latest two songs and news! Want to be on The Rock Metal Podcast? Email Jon at TheRockMetalPodcast@gmail.com Want to support The Rock Metal Podcast? Donate here: https://www.paypal.me/JonJHarris Want to be on our newsletter list? Provide your email address at https://mailchi.mp/af7a2332e334/therockmetalpodcastnewsletter
"Of course I have a fond affection for that song obviously for personal reason," Bruce Hornsby says of Tupac's 'Changes,' one of his six protest songs of choice on this week's People Have The Power. "That song is my song, 'The Way It Is,' with new words. I love the lyrics, such a positive message, such a soulful message. And now again it's achieved this pantheon status where I've been sent several videos from around the world, one of the most beautiful ones came from New Zealand, where there are these protests and Tupac's ;Changes' is playing and hundreds of people are singing along, they know every word. "
As Annie Mac, she is the globetrotting DJ who's been shaping our music tastes since 2006, as part of Radio 1's evening line-up. Going by her full name, she is also host of the 'Changes' podcast. Her first novel is called 'Mother Mother'.
'Changes occur all the time. They can be identifiable and dramatic, or they can emerge imperceptibly, creeping up on you until one day you realise your foundations are less solid than you imagined. At this point in your life you need to find a new path.' Coping with transition can be hard at every stage of life, but it presents unique challenges as we come to the time of our lives when we are facing the end of full-on, full-time work. Changing Gear looks at why work is such an important part of a person's identity, and how challenging it can be when it's time to change gear, whether that's to explore a new path or take a step back from our careers entirely. Offering insight, advice and practical exercises to help you make the right decisions, this valuable guide gives you the tools to navigate complicated situations, identify what's most important, and develop the skills you need to cope with change.
Mugambi landed his first acting gig at age 5, as the little drummer boy in his nursery school Nativity. The reviews were excellent. His career would really begin decades later, with appearances in plays and musicals in different stages in Nairobi. It's when he found himself jobless in America in the middle of the 2008 recession that things got exciting. He joined Philadelphia's acting scene, appearing in independent stage plays and short films, and telling stories about American history to tourists in the summer. On returning to Nairobi, he landed principal roles in M-Net's pan-African TV drama 'Changes', and the celebrated Kenyan films 'Nairobi Half Life' and 'Stories Of Our Lives'. After gaining some writing experience on the 'Village Series' of comedy musicals, he created, co-wrote and co-directed 'Groove Theory', a musical drama TV series that ran for two seasons on regional cable TV. In 2014, Mugambi curated and directed 'Stories From The Mall', a theatre tribute to the events of the 2013 Westgate terrorist attack. In 2015, he co-wrote 'Kati Kati' a feature film co-written and directed by Mbithi Masya. Kati Kati premiered at the Toronto International Film Festival 2016 where it was awarded the FIPRESCI Prize. It went on to win the award for Best Film at Sweden's CinemAfrica Festival, a New Voices/New Visions Special Mention at the Palm Springs International Film Festival and the award for Best East African Film at the Africa Magic Viewers' Choice Awards. In 2017, he co-wrote 'Supa Modo', a family film directed by Likarion Wainaina, which premiered at the 68th Berlin International Film Festival 2018, and was awarded a Special Mention from the Generation Kplus Jury. Supa Modo continues a spirited worldwide festival run and is still winning the adoration of viewers and critics.
Mugambi landed his first acting gig at age 5, as the little drummer boy in his nursery school Nativity. The reviews were excellent. His career would really begin decades later, with appearances in plays and musicals in different stages in Nairobi. It's when he found himself jobless in America in the middle of the 2008 recession that things got exciting. He joined Philadelphia's acting scene, appearing in independent stage plays and short films, and telling stories about American history to tourists in the summer. On returning to Nairobi, he landed principal roles in M-Net's pan-African TV drama 'Changes', and the celebrated Kenyan films 'Nairobi Half Life' and 'Stories Of Our Lives'. After gaining some writing experience on the 'Village Series' of comedy musicals, he created, co-wrote and co-directed 'Groove Theory', a musical drama TV series that ran for two seasons on regional cable TV. In 2014, Mugambi curated and directed 'Stories From The Mall', a theatre tribute to the events of the 2013 Westgate terrorist attack. In 2015, he co-wrote 'Kati Kati' a feature film co-written and directed by Mbithi Masya. Kati Kati premiered at the Toronto International Film Festival 2016 where it was awarded the FIPRESCI Prize. It went on to win the award for Best Film at Sweden's CinemAfrica Festival, a New Voices/New Visions Special Mention at the Palm Springs International Film Festival and the award for Best East African Film at the Africa Magic Viewers' Choice Awards. In 2017, he co-wrote 'Supa Modo', a family film directed by Likarion Wainaina, which premiered at the 68th Berlin International Film Festival 2018, and was awarded a Special Mention from the Generation Kplus Jury. Supa Modo continues a spirited worldwide festival run and is still winning the adoration of viewers and critics.
Mugambi landed his first acting gig at age 5, as the little drummer boy in his nursery school Nativity. The reviews were excellent. His career would really begin decades later, with appearances in plays and musicals in different stages in Nairobi. It's when he found himself jobless in America in the middle of the 2008 recession that things got exciting. He joined Philadelphia's acting scene, appearing in independent stage plays and short films, and telling stories about American history to tourists in the summer. On returning to Nairobi, he landed principal roles in M-Net's pan-African TV drama 'Changes', and the celebrated Kenyan films 'Nairobi Half Life' and 'Stories Of Our Lives'. After gaining some writing experience on the 'Village Series' of comedy musicals, he created, co-wrote and co-directed 'Groove Theory', a musical drama TV series that ran for two seasons on regional cable TV. In 2014, Mugambi curated and directed 'Stories From The Mall', a theatre tribute to the events of the 2013 Westgate terrorist attack. In 2015, he co-wrote 'Kati Kati' a feature film co-written and directed by Mbithi Masya. Kati Kati premiered at the Toronto International Film Festival 2016 where it was awarded the FIPRESCI Prize. It went on to win the award for Best Film at Sweden's CinemAfrica Festival, a New Voices/New Visions Special Mention at the Palm Springs International Film Festival and the award for Best East African Film at the Africa Magic Viewers' Choice Awards. In 2017, he co-wrote 'Supa Modo', a family film directed by Likarion Wainaina, which premiered at the 68th Berlin International Film Festival 2018, and was awarded a Special Mention from the Generation Kplus Jury. Supa Modo continues a spirited worldwide festival run and is still winning the adoration of viewers and critics.
Mugambi landed his first acting gig at age 5, as the little drummer boy in his nursery school Nativity. The reviews were excellent. His career would really begin decades later, with appearances in plays and musicals in different stages in Nairobi. It's when he found himself jobless in America in the middle of the 2008 recession that things got exciting. He joined Philadelphia's acting scene, appearing in independent stage plays and short films, and telling stories about American history to tourists in the summer. On returning to Nairobi, he landed principal roles in M-Net's pan-African TV drama 'Changes', and the celebrated Kenyan films 'Nairobi Half Life' and 'Stories Of Our Lives'. After gaining some writing experience on the 'Village Series' of comedy musicals, he created, co-wrote and co-directed 'Groove Theory', a musical drama TV series that ran for two seasons on regional cable TV. In 2014, Mugambi curated and directed 'Stories From The Mall', a theatre tribute to the events of the 2013 Westgate terrorist attack. In 2015, he co-wrote 'Kati Kati' a feature film co-written and directed by Mbithi Masya. Kati Kati premiered at the Toronto International Film Festival 2016 where it was awarded the FIPRESCI Prize. It went on to win the award for Best Film at Sweden's CinemAfrica Festival, a New Voices/New Visions Special Mention at the Palm Springs International Film Festival and the award for Best East African Film at the Africa Magic Viewers' Choice Awards. In 2017, he co-wrote 'Supa Modo', a family film directed by Likarion Wainaina, which premiered at the 68th Berlin International Film Festival 2018, and was awarded a Special Mention from the Generation Kplus Jury. Supa Modo continues a spirited worldwide festival run and is still winning the adoration of viewers and critics.
Mugambi landed his first acting gig at age 5, as the little drummer boy in his nursery school Nativity. The reviews were excellent. His career would really begin decades later, with appearances in plays and musicals in different stages in Nairobi. It's when he found himself jobless in America in the middle of the 2008 recession that things got exciting. He joined Philadelphia's acting scene, appearing in independent stage plays and short films, and telling stories about American history to tourists in the summer. On returning to Nairobi, he landed principal roles in M-Net's pan-African TV drama 'Changes', and the celebrated Kenyan films 'Nairobi Half Life' and 'Stories Of Our Lives'. After gaining some writing experience on the 'Village Series' of comedy musicals, he created, co-wrote and co-directed 'Groove Theory', a musical drama TV series that ran for two seasons on regional cable TV. In 2014, Mugambi curated and directed 'Stories From The Mall', a theatre tribute to the events of the 2013 Westgate terrorist attack. In 2015, he co-wrote 'Kati Kati' a feature film co-written and directed by Mbithi Masya. Kati Kati premiered at the Toronto International Film Festival 2016 where it was awarded the FIPRESCI Prize. It went on to win the award for Best Film at Sweden's CinemAfrica Festival, a New Voices/New Visions Special Mention at the Palm Springs International Film Festival and the award for Best East African Film at the Africa Magic Viewers' Choice Awards. In 2017, he co-wrote 'Supa Modo', a family film directed by Likarion Wainaina, which premiered at the 68th Berlin International Film Festival 2018, and was awarded a Special Mention from the Generation Kplus Jury. Supa Modo continues a spirited worldwide festival run and is still winning the adoration of viewers and critics.
Mugambi landed his first acting gig at age 5, as the little drummer boy in his nursery school Nativity. The reviews were excellent. His career would really begin decades later, with appearances in plays and musicals in different stages in Nairobi. It's when he found himself jobless in America in the middle of the 2008 recession that things got exciting. He joined Philadelphia's acting scene, appearing in independent stage plays and short films, and telling stories about American history to tourists in the summer. On returning to Nairobi, he landed principal roles in M-Net's pan-African TV drama 'Changes', and the celebrated Kenyan films 'Nairobi Half Life' and 'Stories Of Our Lives'. After gaining some writing experience on the 'Village Series' of comedy musicals, he created, co-wrote and co-directed 'Groove Theory', a musical drama TV series that ran for two seasons on regional cable TV. In 2014, Mugambi curated and directed 'Stories From The Mall', a theatre tribute to the events of the 2013 Westgate terrorist attack. In 2015, he co-wrote 'Kati Kati' a feature film co-written and directed by Mbithi Masya. Kati Kati premiered at the Toronto International Film Festival 2016 where it was awarded the FIPRESCI Prize. It went on to win the award for Best Film at Sweden's CinemAfrica Festival, a New Voices/New Visions Special Mention at the Palm Springs International Film Festival and the award for Best East African Film at the Africa Magic Viewers' Choice Awards. In 2017, he co-wrote 'Supa Modo', a family film directed by Likarion Wainaina, which premiered at the 68th Berlin International Film Festival 2018, and was awarded a Special Mention from the Generation Kplus Jury. Supa Modo continues a spirited worldwide festival run and is still winning the adoration of viewers and critics.
Mugambi landed his first acting gig at age 5, as the little drummer boy in his nursery school Nativity. The reviews were excellent. His career would really begin decades later, with appearances in plays and musicals in different stages in Nairobi. It's when he found himself jobless in America in the middle of the 2008 recession that things got exciting. He joined Philadelphia's acting scene, appearing in independent stage plays and short films, and telling stories about American history to tourists in the summer. On returning to Nairobi, he landed principal roles in M-Net's pan-African TV drama 'Changes', and the celebrated Kenyan films 'Nairobi Half Life' and 'Stories Of Our Lives'. After gaining some writing experience on the 'Village Series' of comedy musicals, he created, co-wrote and co-directed 'Groove Theory', a musical drama TV series that ran for two seasons on regional cable TV. In 2014, Mugambi curated and directed 'Stories From The Mall', a theatre tribute to the events of the 2013 Westgate terrorist attack. In 2015, he co-wrote 'Kati Kati' a feature film co-written and directed by Mbithi Masya. Kati Kati premiered at the Toronto International Film Festival 2016 where it was awarded the FIPRESCI Prize. It went on to win the award for Best Film at Sweden's CinemAfrica Festival, a New Voices/New Visions Special Mention at the Palm Springs International Film Festival and the award for Best East African Film at the Africa Magic Viewers' Choice Awards. In 2017, he co-wrote 'Supa Modo', a family film directed by Likarion Wainaina, which premiered at the 68th Berlin International Film Festival 2018, and was awarded a Special Mention from the Generation Kplus Jury. Supa Modo continues a spirited worldwide festival run and is still winning the adoration of viewers and critics.
Mugambi landed his first acting gig at age 5, as the little drummer boy in his nursery school Nativity. The reviews were excellent. His career would really begin decades later, with appearances in plays and musicals in different stages in Nairobi. It's when he found himself jobless in America in the middle of the 2008 recession that things got exciting. He joined Philadelphia's acting scene, appearing in independent stage plays and short films, and telling stories about American history to tourists in the summer. On returning to Nairobi, he landed principal roles in M-Net's pan-African TV drama 'Changes', and the celebrated Kenyan films 'Nairobi Half Life' and 'Stories Of Our Lives'. After gaining some writing experience on the 'Village Series' of comedy musicals, he created, co-wrote and co-directed 'Groove Theory', a musical drama TV series that ran for two seasons on regional cable TV. In 2014, Mugambi curated and directed 'Stories From The Mall', a theatre tribute to the events of the 2013 Westgate terrorist attack. In 2015, he co-wrote 'Kati Kati' a feature film co-written and directed by Mbithi Masya. Kati Kati premiered at the Toronto International Film Festival 2016 where it was awarded the FIPRESCI Prize. It went on to win the award for Best Film at Sweden's CinemAfrica Festival, a New Voices/New Visions Special Mention at the Palm Springs International Film Festival and the award for Best East African Film at the Africa Magic Viewers' Choice Awards. In 2017, he co-wrote 'Supa Modo', a family film directed by Likarion Wainaina, which premiered at the 68th Berlin International Film Festival 2018, and was awarded a Special Mention from the Generation Kplus Jury. Supa Modo continues a spirited worldwide festival run and is still winning the adoration of viewers and critics.
Mugambi landed his first acting gig at age 5, as the little drummer boy in his nursery school Nativity. The reviews were excellent. His career would really begin decades later, with appearances in plays and musicals in different stages in Nairobi. It's when he found himself jobless in America in the middle of the 2008 recession that things got exciting. He joined Philadelphia's acting scene, appearing in independent stage plays and short films, and telling stories about American history to tourists in the summer. On returning to Nairobi, he landed principal roles in M-Net's pan-African TV drama 'Changes', and the celebrated Kenyan films 'Nairobi Half Life' and 'Stories Of Our Lives'. After gaining some writing experience on the 'Village Series' of comedy musicals, he created, co-wrote and co-directed 'Groove Theory', a musical drama TV series that ran for two seasons on regional cable TV. In 2014, Mugambi curated and directed 'Stories From The Mall', a theatre tribute to the events of the 2013 Westgate terrorist attack. In 2015, he co-wrote 'Kati Kati' a feature film co-written and directed by Mbithi Masya. Kati Kati premiered at the Toronto International Film Festival 2016 where it was awarded the FIPRESCI Prize. It went on to win the award for Best Film at Sweden's CinemAfrica Festival, a New Voices/New Visions Special Mention at the Palm Springs International Film Festival and the award for Best East African Film at the Africa Magic Viewers' Choice Awards. In 2017, he co-wrote 'Supa Modo', a family film directed by Likarion Wainaina, which premiered at the 68th Berlin International Film Festival 2018, and was awarded a Special Mention from the Generation Kplus Jury. Supa Modo continues a spirited worldwide festival run and is still winning the adoration of viewers and critics.
This week Davis discusses People's 'Sexiest Man Alive 2020' Michael B. Jordan joining Onlyfans, The Grammy's, Justin Bieber's "R&B" Plea and The Five Things He's Thankful For. ‘Sexiest Man Alive' Michael B. Jordan Is Joining OnlyFans For A Cause [Video] | lovebscott.com https://carmndv.us/378cH4y The Recording Academy Invites 2,300 New Members - Rolling Stone https://carmndv.us/3m7wFm1 Justin Bieber is unhappy with the Grammys' pop classification of his album 'Changes' | NME https://carmndv.us/2KIKF87
Laat Je Horen! is een podcast van Kargadoor Podium, uit hartje Utrecht. We gaan in gesprek met de bijzondere stemmen uit Utrecht. Toffe verhalen, inspirerende bijdragen aan ons stadsie en de toekomst; what's next? Deze aflevering spreken we Joep Jansen, artiest en initiatiefnemer van U-RAP, de hiphop open mic van Utrecht. We praten over zijn tijd in New York, krijgen een beginnerscursus in rap en hiphop én hebben partner in crime Elvis David over de vloer voor een akoestische versie van hun nummer 'Changes'. Kargadoor Podium komt elke woensdag om 11.00 uur met een nieuwe aflevering van Laat Je Horen!. Wil jij bijdragen of heb je een tip voor een gast uit Utrecht die we moeten spreken? Mail ons naar pr@kargadoor.nl! www.kargadoor.nl @dekargadoor Joep Jansen: @juhpyther Elvis David: @groovvy_e Luister naar 'Changes': https://www.youtube.com/watch?v=Dw9naA4NG00
Co-hosts Caitlin White and Eric Fulcher's seventh episode of the first season of State Of Grace is a doozy. Justin Bieber has a new album out called Changes, but the music is more than overshadowed by the advent of his new marriage to Hailey Baldwin. Is the new album any good? Why was "Yummy" a flop?Which songs on the album should’ve actually been the singles?And does it bode well for his marriage to release an album devoted to it just a few months after? We answer all this and more in the episode.
Billie Eilish releases James Bond theme, Madonna is a record queen and Justin Bieber drops 'Changes.' This is Billboard New Now rounding out the top stories for Friday, February 14.
We are back with another ‘Bakery Bears Radio Show'. This second episode of the show is entitled ‘Changes'. Join your hosts, Kay and Dan on another country walk. This time they are discussing the changes Dan's battle with cancer brought for both of them. But the focus of the show very much is on the realisation they wanted to drastically change their every day lives, but they weren't quite sure how they were going to do it! You can visit our ‘Radio Show' website page here www.bakerybears.com/listen/ - You'll find information about the show, a link to our brand new ‘The Bakery Bears Radio Show' Facebook page and more. Follow the Bakery Bears on Twitter https://twitter.com/bakerybears Follow the Bakery Bears on Facebook https://www.facebook.com/bakerybears/
Help Host BRichie Welcome Guest Of The Week Chicago Entrepreneurs &&. Clothing Designer, Chuck Moo Of Icon The Collection. Listen As BRichie Talks About The 'Changes Happen'. Find Out About Icon The Collection &&. Everything Chuck Moo Has In Store For The Brand. Listen As They Talk About Being Entrepreneurs In Chicago, His Brand Icon The Collection, Posting Your Significant Other On Social Media &&. Much More. Check Out This Week's Episode Of BroCode By BRichie &&. Don't Break The Code! --- Support this podcast: https://anchor.fm/brocodebybrichie/support
Hey gang! Here we have The Tritones from Santa Ana, CA. Right from the heart of where we film and record. Check out the full post on our website for more content including a FREE download of the podcast with an extra song: https://bit.ly/2OWOC6R Follow and Like The Tritones on the internet: https://www.instagram.com/tritonesband/ https://thetritones5.bandcamp.com/releases Click like, subscribe, follow, etc on all of our websites: https://www.facebook.com/kilsonstreettv https://www.instagram.com/kilsonstreet https://www.twitter.com/kilsonstreet https://www.soundcloud.com/kilsonstreet https://www.stitcher.com/podcast/kilson-street See ya hasta luego muchachos and muchachas.
¡Bienvenido a los Vinilos de Barbarella! El podcast donde sólo se escucha música en formato de vinlo. Este el programa número 1, dedicado al disco 'ChangesOneBowie' de David Bowie, en la edición limitada 40 aniversario en color transparente. Los datos de dicha edición son: Código de barras: 0190295994082 Label Code: LC30419 Los temas que reseñamos son: 'Changes'; 'Rebel, Rebel'; 'Fame'; 'Golden Years' y 'John, I'm Only Dancing'. Incluimos la reseña del vinilo y los apartados de noticias y efemérides. Los enlaces que aparecen en el Podcast son los siguientes: Web Oficial de David Bowie: http://www.davidbowie.com Museo online de Prince: http://princeonlinemuseum.com No olvides dejar tu comentarios. Ponte en contacto con nosotros: e-mail: info@barbarellavinyls.com Web: http://www.barbarellavinyls.com Facebook: http://facebook.com/barbarellavinyls2 Twitter: @barbarellavinyl Flickr: https://www.flickr.com/photos/116847885@N05/show/
No Shirt, No Shoes, Pants Optional, the comedy podcast that doesn't care if you are wearing pants, or not. On our sixth show, the theme is aliens. The show features an interview with an alien from another planet, another Pants Optional podcast first. Plus the usual assortment of interviews with experts, This Week in Animal Behaviour, John's Word A Day and the continuing dramatic nonsense entitled 'Changes at the Office.'
No Shirt, No Shoes, Pants Optional, the comedy podcast that doesn't care if you are wearing pants, or not. On our sixth show, the theme is aliens. The show features an interview with an alien from another planet, another Pants Optional podcast first. Plus the usual assortment of interviews with experts, This Week in Animal Behaviour, John's Word A Day and the continuing dramatic nonsense entitled 'Changes at the Office.'
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