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2 episodes with huygen
Summary In this episode of the Pain Exam Podcast, Dr. David Rosenblum provides a comprehensive review of herpes zoster and postherpetic neuralgia (PHN), focusing on pathophysiology, diagnosis, and treatment options. Dr. Rosenblum explains that postherpetic neuralgia affects approximately 25% of patients with acute herpes zoster, causing debilitating unilateral chronic pain in one or more dermatomes. He discusses the three phases of herpes zoster: acute (up to 30 days), subacute (up to 3 months), and postherpetic neuralgia (pain continuing beyond 3 months). Dr. Rosenblum identifies risk factors for developing PHN, including older age, female sex, immunosuppression, prodromal pain, severe rash, and greater acute pain severity. He details the pathophysiology involving peripheral and central sensitization, and explains different phenotypes of PHN that can guide treatment approaches. For treatment, Dr. Rosenblum reviews various options including antiviral medications (which should be started within 72 hours of onset), corticosteroids, opioids, antidepressants (particularly tricyclics and SNRIs), antiepileptics (gabapentin and pregabalin), topical agents (lidocaine and capsaicin), and interventional procedures such as epidural injections and pulsed radiofrequency. He emphasizes that prevention through vaccination with Shingrix is highly effective, with 97% effectiveness in preventing herpes zoster in patients 50-69 years old and 89% effectiveness in those over 70. Dr. Rosenblum mentions that he's currently treating a patient with trigeminal postherpetic neuralgia and is considering a topical sphenopalatine ganglion block as a minimally invasive intervention before attempting more invasive procedures. Chapters Introduction to the Pain Exam Podcast and Topic Overview Dr. David Rosenblum introduces the Pain Exam Podcast, mentioning that it covers painful disorders, alternative treatments, and practice management. He explains that this episode focuses on herpes zoster and postherpetic neuralgia as board preparation for fellows starting their programs, with ABA boards coming up in September. Dr. Rosenblum notes that he's not only preparing listeners for boards but also seeking the latest information to help treat his own patients with this notoriously difficult disease. Upcoming Conferences and Educational Opportunities Dr. Rosenblum announces several upcoming conferences including Aspen in July, Pain Week in September, and events with NYSIP and the Latin American Pain Society. He mentions he'll be teaching ultrasound and regenerative medicine at these events. Dr. Rosenblum invites listeners to sign up at nrappain.org to access a community discussing regenerative medicine, ultrasound-guided pain medicine, regional anesthesia, and board preparation. He also offers ultrasound training in New York and elsewhere, with upcoming sessions in Manhattan on July 12th and October 4th, plus private shadowing opportunities. Overview of Postherpetic Neuralgia Dr. Rosenblum defines postherpetic neuralgia as typically a unilateral chronic pain in one or more dermatomes after acute herpes zoster infection. He states that the incidence of acute herpes zoster ranges between 3-5 patients per thousand person-years, and one in four patients with acute herpes zoster-related pain will transition into postherpetic neuralgia. Dr. Rosenblum emphasizes that while this condition won't kill patients, it can be extremely debilitating and significantly reduce quality of life. Treatment Options Overview Dr. Rosenblum reviews treatment options according to the WHO pain ladder, including tricyclics like nortriptyline and antiepileptic drugs such as gabapentin. He explains that if pain is not significantly reduced, interventional treatments like epidural injections with local anesthetics and corticosteroids or pulsed radiofrequency of the dorsal root ganglion are options. For postherpetic neuralgia specifically, Dr. Rosenblum notes that preferred treatments include transdermal capsaicin, lidocaine, or oral drugs such as antidepressants or antiepileptics. Phases of Herpes Zoster and Definitions Dr. Rosenblum outlines the three phases during herpes zoster reactivation: acute herpes zoster-related pain (lasting maximum 30 days), subacute herpes zoster-related pain (pain after healing of vesicles but disappearing within 3 months), and postherpetic neuralgia (typically defined as pain continuing after 3 months). He mentions that acute herpes zoster pain often begins with prodromal pain starting a few days before the appearance of the rash. Incidence and Risk Factors Dr. Rosenblum states that the incidence of herpes zoster ranges between 3-5 patients per 1,000 person-years, with approximately 5-30% of cases leading to postherpetic neuralgia. He identifies risk factors including older age, female sex, immunosuppression, prodromal pain, severe rash, and greater acute pain severity. Dr. Rosenblum describes the clinical manifestations as a mosaic of somatosensory symptoms including burning, deep aching pain, tingling, itching, stabbing, often associated with tactile and cold allodynia. Impact on Quality of Life Dr. Rosenblum emphasizes that postherpetic neuralgia can be debilitating, impacting both physical and emotional functioning and causing decreased quality of life. He notes that it leads to fatigue, insomnia, depression, anorexia, anxiety, and emotional distress. Dr. Rosenblum stresses the importance of exploring methods for prevention of postherpetic neuralgia and optimizing pain treatment for both subacute herpes zoster-related pain and postherpetic neuralgia. Literature Review and Pathophysiology Dr. Rosenblum mentions that he's discussing a literature review from 2024 that updates previous practical guidelines published in 2011. He explains the pathophysiology of postherpetic neuralgia, which involves sensitization of peripheral and sensory nerves from damage. Dr. Rosenblum describes how inflammatory mediators reduce the stimulus threshold of nociceptors and increase responsiveness, resulting in pathological spontaneous discharges, lower thresholds for thermal and mechanical stimuli, and hyperalgesia. Central Sensitization and Nerve Damage Dr. Rosenblum explains that central sensitization results from peripheral nociceptor hyperactivity leading to plastic changes in the central nervous system, involving amplification of pain signals and reduced inhibition. He describes how nerve damage in postherpetic neuralgia patients results from neuronal death due to severe inflammatory stimuli or secondary to neuronal swelling. Dr. Rosenblum notes that motor defects occur in 0.05% of patients with herpes zoster, observed as abdominal pseudohernias or motor weakness of limbs limited to the affected myotome. Different Phenotypes and Classification Dr. Rosenblum discusses different phenotypes of postherpetic neuralgia and how phenotyping can determine treatment. He explains that there are several ways to classify the phenotypes, with one categorizing patients into three subtypes: sensory loss (most common), thermal gain, and thermal loss with mechanical gain. Dr. Rosenblum describes the mechanistic categorization, including the irritable nociceptive phenotype characterized by preserved sensation, profound dynamic mechanical allodynia, reduced pressure pain threshold, and relief with local anesthetic infiltration. Deafferentation Phenotype Dr. Rosenblum explains that a deafferentation phenotype may arise from destruction of neurons by the virus in the dorsal root ganglion. This phenotype is characterized by sensory loss, including thermal and vibratory sensation without prominent thermal allodynia. He notes that mechanical allodynia can occur secondary to A-beta fibers activating spinothalamic pathways (known as phenotypic switches), along with pressure hyperalgesia and temporal summation suggesting central sensitization. Dr. Rosenblum mentions that in one study, this phenotype was present in 10.8% of individuals, and for those with deafferentation pain, gabapentinoids, antidepressants, and neuromodulatory therapies like repetitive transcranial magnetic stimulation may be beneficial. Diagnosis and Physical Examination Dr. Rosenblum discusses the diagnosis of herpes zoster and postherpetic neuralgia, emphasizing the importance of physical examination. He explains that diagnosis is based on the rash, redness, papules, and vesicles in the painful dermatomes, with healing vesicles showing crust formation. Dr. Rosenblum notes that the rash is generally unilateral and does not cross the midline of the body. In postherpetic neuralgia patients, he mentions that scarring, hyper or hypopigmentation is often visible, with allodynia present in 45-75% of affected patients. Sensory Testing and Assessment Dr. Rosenblum explains that in patients with postherpetic neuralgia, a mosaic of somatosensory alterations can occur, manifesting as hyperalgesia, allodynia, and sensory loss. These can be quantified by quantitative sensory testing, which assesses somatosensory functions, dermal detection thresholds for perception of cold, warmth, and paradoxical heat sensations. He notes that testing can provide clues regarding underlying mechanisms of pain, impaired conditioned pain modulation, temporal summation suggesting central sensitization, and information about the type of nerve damage and surviving afferent neurons. Prevention Through Vaccination Dr. Rosenblum discusses prevention of acute herpes zoster through vaccination, noting that the risk increases with reduced immunity. He highlights studies evaluating Shingrix, a vaccine for herpes zoster, which showed 97% effectiveness in preventing herpes zoster in patients 50-69 years old with healthy immune systems and 89% effectiveness in patients over 70. Dr. Rosenblum states that Shingrix is 89-91% effective in preventing postherpetic neuralgia development in patients with healthy immune systems and 68-91% effective in those with weakened or underlying conditions. Treatment Objectives Dr. Rosenblum outlines the treatment objectives for herpes zoster and postherpetic neuralgia. For acute herpes zoster, objectives include relieving pain, reducing severity and duration of pain, accelerating recovery of epidermal defects, and preventing secondary infections. For postherpetic neuralgia, the objectives are pain alleviation and improved quality of life. Dr. Rosenblum lists available treatments including psychotherapy, opiates, antidepressants, antiepileptics, NMDA antagonists, topical agents, and interventional treatments such as epidurals, pulsed radiofrequency, nerve blocks, and spinal cord stimulation. Antiviral Medications Dr. Rosenblum emphasizes that antiviral drugs should be started within 72 hours of clinical onset, mentioning famciclovir, valacyclovir, and acyclovir. He notes there is no evidence for effectiveness after 72 hours in patients with uncomplicated herpes zoster. Dr. Rosenblum provides dosing information: for immunocompetent patients, famciclovir 500mg and valacyclovir 1000mg three times daily for seven days; for immunocompromised patients, famciclovir 1000mg three times daily for 10 days, while acyclovir should be given IV in the immunocompromised. Benefits of Antiviral Therapy Dr. Rosenblum explains that antiviral medication accelerates the disappearance of vesicles and crusts, promotes healing of skin lesions, and prevents new lesions from forming. By inhibiting viral replication, he notes that antiviral therapy likely reduces nerve damage, resulting in reduced incidence of postherpetic neuralgia, and should be started as soon as possible. Corticosteroids and Opioids Dr. Rosenblum discusses the use of corticosteroids, noting that when added to antiviral medications, they may reduce the severity of acute herpes zoster-related pain, though increased healing of skin lesions was not observed in one study. He mentions that a Cochrane review found oral corticosteroids ineffective in preventing postherpetic neuralgia. Regarding opioids, Dr. Rosenblum states they are commonly used alongside antivirals for controlling acute herpes zoster pain, with tramadol having a number needed to treat (NNT) of 4.7 and strong opioids having an NNT of 4.3 for 50% pain reduction. Methadone and Antidepressants Dr. Rosenblum discusses methadone as an NMDA receptor antagonist used in acute and chronic pain management, though he notes there are no randomized controlled trials determining its efficacy in acute herpes zoster pain or postherpetic neuralgia. He explains that methadone can modulate pain stimuli by inhibiting the uptake of norepinephrine and serotonin, resulting in decreased development of hyperalgesia and opioid tolerance, but has side effects including constipation, nausea, sedation, and QT prolongation that can trigger torsades de pointes. Dr. Rosenblum identifies antidepressants as first-line therapy for postherpetic neuralgia, including tricyclics and SNRIs, with tricyclics having an NNT of 3 and SNRIs an NNT of 6.4 for 50% pain reduction. Antiepileptics and Pharmacological Treatment Summary Dr. Rosenblum discusses antiepileptics like gabapentin and pregabalin for postherpetic neuralgia. He cites two trials measuring gabapentin's effect, concluding it was effective compared to placebo with a pooled NNT of 4.4, while pregabalin had an NNT of 4.9. Dr. Rosenblum summarizes that pharmacological treatment is well established for subacute herpes zoster pain, though new high-quality evidence has been lacking since the last update in 2011. Topical Agents Dr. Rosenblum discusses local anesthetic topical agents including lidocaine and capsaicin creams and patches. He notes that 8% capsaicin provided significant pain reduction during 2-8 weeks, while 5% lidocaine patches provided moderate pain relief after eight weeks of treatment. Dr. Rosenblum also mentions acute herpes zoster intracutaneous injections, citing a study where single intracutaneous injection with methylprednisolone combined with ropivacaine versus saline alone showed significant difference in VAS score at 1 and 4 weeks post-intervention favoring the intervention group. Intracutaneous Injections Dr. Rosenblum discusses the effect of repetitive intracutaneous injections with ropivacaine and methylprednisolone every 48 hours for one week. He cites a randomized control trial comparing antivirals plus analgesics to antivirals plus analgesics and repeat injections, finding the intervention group had significantly shorter duration of pain, lower VAS scores, and lower incidence of postherpetic neuralgia (6.4% vs 28% at 3 months). Dr. Rosenblum notes that a potential side effect of cutaneous methylprednisolone injection is fat atrophy, though this wasn't reported in the study. Summary of Local Anesthetics Dr. Rosenblum summarizes that there are no new studies reporting the efficacy of capsaicin 8% for postherpetic neuralgia, but it remains widely used in clinical practice and is approved in several countries. He notes that lidocaine patches can reduce pain intensity in patients with postherpetic neuralgia but may be more beneficial in patients with allodynia. Dr. Rosenblum adds that intracutaneous injections may be helpful for short periods, while repetitive injections with local anesthetics may reduce VAS scores for up to six months but can cause subcutaneous fat atrophy. Interventional Treatments: Epidural and Paravertebral Injections Dr. Rosenblum discusses interventional treatments, noting that previous guidelines found epidural injection with corticosteroids and local anesthetic as add-on therapy superior to standard care alone for up to one month in managing acute herpes zoster pain. He mentions a randomized controlled trial showing no difference between interlaminar and transforaminal epidural steroid injections for up to three months after the procedure. Dr. Rosenblum adds that previous guidelines reported high-quality evidence that paravertebral injections of corticosteroids or local anesthetic reduces pain in the active phase of herpes zoster. Comparative Studies on Injection Approaches Dr. Rosenblum discusses a trial comparing efficacy of repetitive paravertebral blocks with ropivacaine versus dexmedetomidine to prevent postherpetic neuralgia, which showed significantly lower incidence of zoster-related pain one month after therapy in the dexmedetomidine group, with effects still significant at three months. He also mentions a study comparing steroid injections administered via interlaminar versus transforaminal approaches, finding both groups had significantly lower VAS scores at 1 and 3 months follow-up compared to baseline, though this could align with the natural course of herpes zoster. Timing of Interventions and Continuous Epidural Blockade Dr. Rosenblum cites a retrospective study showing that transforaminal epidural injections administered for acute herpes zoster-related pain were associated with significantly shorter time to pain relief compared to those performed in the subacute phase. He also mentions a randomized controlled trial finding that continuous epidural blockade combined with opioids and gabapentin reduced NRS pain scores more than analgesic drug treatments alone during three-day follow-up, though both studies were low-quality. Interventions for Postherpetic Neuralgia Dr. Rosenblum discusses interventions specifically for postherpetic neuralgia, citing a small randomized controlled trial that demonstrated decreased NRS pain scores six months post-treatment for repeat versus single epidural steroid injections (15mg vs 5mg dexamethasone) administered over 24 days. The trial also found increased likelihood of complete remission during 6-month follow-up in the group receiving repeat epidural dexamethasone, though this was low-quality evidence. Summary of Epidural and Paravertebral Injections Dr. Rosenblum summarizes that epidural or paravertebral injections of local anesthetic and/or glucocorticoids could be considered in treating acute herpes zoster-related pain. For subacute postherpetic neuralgia pain, he notes low-quality evidence supporting epidural injections, while for postherpetic neuralgia, evidence supports continuous epidural infusion, though also of low quality. Dr. Rosenblum emphasizes that none of the included studies for postherpetic neuralgia investigating epidural or paravertebral injections resulted in decreased pain compared to standard therapy. Pulsed Radiofrequency (PRF) Evidence Dr. Rosenblum discusses pulsed radiofrequency (PRF), noting that previous guidelines indicated moderate quality evidence that PRF of the intercostal nerve reduces pain for 6 months in patients with postherpetic neuralgia, and very low-quality evidence that PRF to the dorsal root ganglion (DRG) reduces pain for 6 months. He mentions that multiple studies have been published since then assessing PRF efficacy. PRF Studies for Acute Herpes Zoster Dr. Rosenblum discusses a randomized controlled trial with 60 patients comparing high-voltage bipolar PRF of the cervical sympathetic chain versus sham, with treatment repeated after three days in both groups. He reports that VAS scores in the PRF group at each post-interventional point (1 day, 2 days, 1 month, 2 months, 3 months) were significantly lower than in the sham group, and at 3 months, the incidence of postherpetic neuralgia was 16.7% in the PRF group compared to 40% in the sham group. PRF for Trigeminal Neuralgia Dr. Rosenblum cites another randomized controlled trial evaluating high-voltage long-duration PRF of the Gasserian ganglion in 96 patients with subacute herpes-related trigeminal neuralgia, which found decreased VAS pain scores at all post-interventional time points (3, 7, 14 days and 1, 3, and 6 months) compared to the sham group. He also mentions a randomized comparative effectiveness study in 120 patients with subacute trigeminal herpes zoster, comparing a single application of high-voltage PRF to the Gasserian ganglion versus three cycles of conventional PRF treatment, finding significantly lower mean VAS pain scores for up to six months in the high-voltage PRF group. PRF Compared to Other Interventions Dr. Rosenblum discusses a randomized controlled trial comparing PRF to short-term spinal cord stimulation, which found decreased pain and improved 36-item short-form health survey scores in both groups at six months. He also mentions a randomized controlled trial in 72 patients where PRF of spinal nerves or peripheral branches of cranial nerves combined with five-day infusion of IV lidocaine resulted in greater pain reduction, less rescue analgesia, and reduced inflammatory cytokines at two months compared to PRF with saline infusions. Dr. Rosenblum notes a major limitation of this study was not accounting for the high natural recovery rate. Summary of PRF and Final Recommendations Dr. Rosenblum summarizes that PRF provides significant pain relief lasting over three months in patients with subacute herpes zoster and postherpetic neuralgia. He notes that since few studies have compared PRF versus sham, it's not possible to calculate an accurate number needed to treat. Dr. Rosenblum mentions there are no comparative studies comparing PRF to the intercostal nerves versus PRF of the DRG, but both preclinical and clinical studies suggest superiority of the DRG approach. He adds that evidence for spinal cord stimulation for postherpetic neuralgia is of low quality, and more research is needed given its invasive nature. Sympathetic Blocks and Conclusion Dr. Rosenblum notes there is low-quality evidence for using sympathetic blocks to treat acute herpes zoster-related pain, but no evidence for their use in postherpetic neuralgia. He mentions that risks of treatment with intrathecal methylprednisolone are unclear and therefore not recommended. Dr. Rosenblum concludes by praising the comprehensive article he's been discussing and mentions it provides insight for treating his patients, including a recent case of trigeminal postherpetic neuralgia. Personal Clinical Approach and Closing Dr. Rosenblum shares that he doesn't currently perform PRF in his practice, partly because it's not standard of care and not well reimbursed, creating barriers to implementation. However, he notes that PRF is a very safe procedure as it doesn't involve burning tissue. For his patient with trigeminal neuralgia pain, Dr. Rosenblum plans to try a topical sphenopalatine ganglion block as the least invasive intervention before considering injecting the trigeminal nerves at the foramen, in addition to pharmacotherapy. He concludes by thanking listeners, encouraging them to check the show notes and links, mentioning institutional memberships and shadowing opportunities, and asking listeners to rate and share the podcast. Q&A No Q&A session in this lecture Pain Management Board Prep Ultrasound Training REGISTER TODAY! Create an Account and get Free Access to the PainExam- NRAP Academy Community Highlights David Rosenblum, MD, currently serves as the Director of Pain Management at Maimonides Medical Center and AABP Integrative Pain Care. As a member of the Department of Anesthesiology, he is involved in teaching, research, CME activities, and was key faculty in developing the anesthesiology residency's regional anesthesia block rotation, as well as institutional wide acute and chronic pain management protocols to ensure safe and effective pain management. He currently is a managing partner in a multi-physician private pain practice, AABP Integrative Pain Care, located in Brooklyn, NY. He is one of the earliest interventional pain physicians to integrate ultrasound guidance to improve the safety and accuracy of interventional pain procedures. Awards New York Magazine: Top Doctors: 2016, 2017, 2018, 2021, 2022, 2023, 2024, 2025 Schneps Media: 2015, 2016, 2017, 2019, 2020 Top Doctors New York Metro Area (digital guide): 2016, 2017, 2018, 2019, 2020, 2021, 2022, 2023 2025 Schneps Media - Brooklyn Courier Life: 2021, 2022, 2023 Dr. Rosenblum written several book chapters on Peripheral Neuromodulation, Radiofrequency Ablation, and Pharmacology. He has published numerous noteworthy articles and most recently is developing the ASIPP Guidelines for Peripheral Neuromodulation in the treatment of chronic pain. He has been named several times in NY Magazine's Best Pain Management Doctor List, Nassau County's Best Pain Physician, has appeared on NY1 News, and has made several appearances on XM Radio's Doctor Talk. He currently is lecturing on a national and international level and has partnered with the American Society of Interventional Pain Physicians (ASIPP), American Society of Pain and Neuroscience (ASPN), IASP Mexican Chapter, Eastern Pain Association (EPA), the North American Neuromodulation Society (NANS), World Academy of Pain Medicine United, as well as various other organizations, to support educational events and develop new courses. Since 2008, he has helped over 3000 physicians pass the Pain Management Boards, and has been at the forefront of utilizing ultrasound guidance to perform pain procedures. He now hosts the PainExam podcast, AnesthesiaExam Podcast, PMRExam Podcasts and uses this platform to promote the safe and effective use of ultrasound in the performance of various procedures such as Peripheral Nerve Stimulation, Caudal Epidurals, Selective Nerve Root Blocks, Cluneal Nerve Blocks, Ganglion impar Blocks, Stellate Ganglion Blocks, Brachial Plexus Blocks, Joint Injections and much more! Doctor Rosenblum created the NRAP (Neuromodulation Regional Anesthesia and Pain) Academy and travels to teach various courses focused on Pain Medicine, Regenerative Medicine, Ultrasound Guided Pain Procedures and Regional Anesthesia Techniques. Dr. Rosenblum is persistent when it comes to eliminating pain and has gained a reputation among his patients for thinking "outside the box" and implements ultrasound guidance to deposit medications, biologics (PRP, Bone Marrow Aspirate, etc.) and Peripheral Nerve Stimulators near pain generators. He is currently treating patients in his great neck and Brooklyn office. For an appointment go to AABPpain.com or call Brooklyn 718 436 7246 Reference Adriaansen, E. J., Jacobs, J. G., Vernooij, L. M., van Wijck, A. J., Cohen, S. P., Huygen, F. J., & Rijsdijk, M. (2025). 8. Herpes zoster and post herpetic neuralgia. Pain Practice, 25(1), e13423.
Summary In this episode of the Pain Exam Podcast, Dr. David Rosenblum provides a comprehensive review of herpes zoster and postherpetic neuralgia (PHN), focusing on pathophysiology, diagnosis, and treatment options. Dr. Rosenblum explains that postherpetic neuralgia affects approximately 25% of patients with acute herpes zoster, causing debilitating unilateral chronic pain in one or more dermatomes. He discusses the three phases of herpes zoster: acute (up to 30 days), subacute (up to 3 months), and postherpetic neuralgia (pain continuing beyond 3 months). Dr. Rosenblum identifies risk factors for developing PHN, including older age, female sex, immunosuppression, prodromal pain, severe rash, and greater acute pain severity. He details the pathophysiology involving peripheral and central sensitization, and explains different phenotypes of PHN that can guide treatment approaches. For treatment, Dr. Rosenblum reviews various options including antiviral medications (which should be started within 72 hours of onset), corticosteroids, opioids, antidepressants (particularly tricyclics and SNRIs), antiepileptics (gabapentin and pregabalin), topical agents (lidocaine and capsaicin), and interventional procedures such as epidural injections and pulsed radiofrequency. He emphasizes that prevention through vaccination with Shingrix is highly effective, with 97% effectiveness in preventing herpes zoster in patients 50-69 years old and 89% effectiveness in those over 70. Dr. Rosenblum mentions that he's currently treating a patient with trigeminal postherpetic neuralgia and is considering a topical sphenopalatine ganglion block as a minimally invasive intervention before attempting more invasive procedures. Chapters Introduction to the Pain Exam Podcast and Topic Overview Dr. David Rosenblum introduces the Pain Exam Podcast, mentioning that it covers painful disorders, alternative treatments, and practice management. He explains that this episode focuses on herpes zoster and postherpetic neuralgia as board preparation for fellows starting their programs, with ABA boards coming up in September. Dr. Rosenblum notes that he's not only preparing listeners for boards but also seeking the latest information to help treat his own patients with this notoriously difficult disease. Upcoming Conferences and Educational Opportunities Dr. Rosenblum announces several upcoming conferences including Aspen in July, Pain Week in September, and events with NYSIP and the Latin American Pain Society. He mentions he'll be teaching ultrasound and regenerative medicine at these events. Dr. Rosenblum invites listeners to sign up at nrappain.org to access a community discussing regenerative medicine, ultrasound-guided pain medicine, regional anesthesia, and board preparation. He also offers ultrasound training in New York and elsewhere, with upcoming sessions in Manhattan on July 12th and October 4th, plus private shadowing opportunities. Overview of Postherpetic Neuralgia Dr. Rosenblum defines postherpetic neuralgia as typically a unilateral chronic pain in one or more dermatomes after acute herpes zoster infection. He states that the incidence of acute herpes zoster ranges between 3-5 patients per thousand person-years, and one in four patients with acute herpes zoster-related pain will transition into postherpetic neuralgia. Dr. Rosenblum emphasizes that while this condition won't kill patients, it can be extremely debilitating and significantly reduce quality of life. Treatment Options Overview Dr. Rosenblum reviews treatment options according to the WHO pain ladder, including tricyclics like nortriptyline and antiepileptic drugs such as gabapentin. He explains that if pain is not significantly reduced, interventional treatments like epidural injections with local anesthetics and corticosteroids or pulsed radiofrequency of the dorsal root ganglion are options. For postherpetic neuralgia specifically, Dr. Rosenblum notes that preferred treatments include transdermal capsaicin, lidocaine, or oral drugs such as antidepressants or antiepileptics. Phases of Herpes Zoster and Definitions Dr. Rosenblum outlines the three phases during herpes zoster reactivation: acute herpes zoster-related pain (lasting maximum 30 days), subacute herpes zoster-related pain (pain after healing of vesicles but disappearing within 3 months), and postherpetic neuralgia (typically defined as pain continuing after 3 months). He mentions that acute herpes zoster pain often begins with prodromal pain starting a few days before the appearance of the rash. Incidence and Risk Factors Dr. Rosenblum states that the incidence of herpes zoster ranges between 3-5 patients per 1,000 person-years, with approximately 5-30% of cases leading to postherpetic neuralgia. He identifies risk factors including older age, female sex, immunosuppression, prodromal pain, severe rash, and greater acute pain severity. Dr. Rosenblum describes the clinical manifestations as a mosaic of somatosensory symptoms including burning, deep aching pain, tingling, itching, stabbing, often associated with tactile and cold allodynia. Impact on Quality of Life Dr. Rosenblum emphasizes that postherpetic neuralgia can be debilitating, impacting both physical and emotional functioning and causing decreased quality of life. He notes that it leads to fatigue, insomnia, depression, anorexia, anxiety, and emotional distress. Dr. Rosenblum stresses the importance of exploring methods for prevention of postherpetic neuralgia and optimizing pain treatment for both subacute herpes zoster-related pain and postherpetic neuralgia. Literature Review and Pathophysiology Dr. Rosenblum mentions that he's discussing a literature review from 2024 that updates previous practical guidelines published in 2011. He explains the pathophysiology of postherpetic neuralgia, which involves sensitization of peripheral and sensory nerves from damage. Dr. Rosenblum describes how inflammatory mediators reduce the stimulus threshold of nociceptors and increase responsiveness, resulting in pathological spontaneous discharges, lower thresholds for thermal and mechanical stimuli, and hyperalgesia. Central Sensitization and Nerve Damage Dr. Rosenblum explains that central sensitization results from peripheral nociceptor hyperactivity leading to plastic changes in the central nervous system, involving amplification of pain signals and reduced inhibition. He describes how nerve damage in postherpetic neuralgia patients results from neuronal death due to severe inflammatory stimuli or secondary to neuronal swelling. Dr. Rosenblum notes that motor defects occur in 0.05% of patients with herpes zoster, observed as abdominal pseudohernias or motor weakness of limbs limited to the affected myotome. Different Phenotypes and Classification Dr. Rosenblum discusses different phenotypes of postherpetic neuralgia and how phenotyping can determine treatment. He explains that there are several ways to classify the phenotypes, with one categorizing patients into three subtypes: sensory loss (most common), thermal gain, and thermal loss with mechanical gain. Dr. Rosenblum describes the mechanistic categorization, including the irritable nociceptive phenotype characterized by preserved sensation, profound dynamic mechanical allodynia, reduced pressure pain threshold, and relief with local anesthetic infiltration. Deafferentation Phenotype Dr. Rosenblum explains that a deafferentation phenotype may arise from destruction of neurons by the virus in the dorsal root ganglion. This phenotype is characterized by sensory loss, including thermal and vibratory sensation without prominent thermal allodynia. He notes that mechanical allodynia can occur secondary to A-beta fibers activating spinothalamic pathways (known as phenotypic switches), along with pressure hyperalgesia and temporal summation suggesting central sensitization. Dr. Rosenblum mentions that in one study, this phenotype was present in 10.8% of individuals, and for those with deafferentation pain, gabapentinoids, antidepressants, and neuromodulatory therapies like repetitive transcranial magnetic stimulation may be beneficial. Diagnosis and Physical Examination Dr. Rosenblum discusses the diagnosis of herpes zoster and postherpetic neuralgia, emphasizing the importance of physical examination. He explains that diagnosis is based on the rash, redness, papules, and vesicles in the painful dermatomes, with healing vesicles showing crust formation. Dr. Rosenblum notes that the rash is generally unilateral and does not cross the midline of the body. In postherpetic neuralgia patients, he mentions that scarring, hyper or hypopigmentation is often visible, with allodynia present in 45-75% of affected patients. Sensory Testing and Assessment Dr. Rosenblum explains that in patients with postherpetic neuralgia, a mosaic of somatosensory alterations can occur, manifesting as hyperalgesia, allodynia, and sensory loss. These can be quantified by quantitative sensory testing, which assesses somatosensory functions, dermal detection thresholds for perception of cold, warmth, and paradoxical heat sensations. He notes that testing can provide clues regarding underlying mechanisms of pain, impaired conditioned pain modulation, temporal summation suggesting central sensitization, and information about the type of nerve damage and surviving afferent neurons. Prevention Through Vaccination Dr. Rosenblum discusses prevention of acute herpes zoster through vaccination, noting that the risk increases with reduced immunity. He highlights studies evaluating Shingrix, a vaccine for herpes zoster, which showed 97% effectiveness in preventing herpes zoster in patients 50-69 years old with healthy immune systems and 89% effectiveness in patients over 70. Dr. Rosenblum states that Shingrix is 89-91% effective in preventing postherpetic neuralgia development in patients with healthy immune systems and 68-91% effective in those with weakened or underlying conditions. Treatment Objectives Dr. Rosenblum outlines the treatment objectives for herpes zoster and postherpetic neuralgia. For acute herpes zoster, objectives include relieving pain, reducing severity and duration of pain, accelerating recovery of epidermal defects, and preventing secondary infections. For postherpetic neuralgia, the objectives are pain alleviation and improved quality of life. Dr. Rosenblum lists available treatments including psychotherapy, opiates, antidepressants, antiepileptics, NMDA antagonists, topical agents, and interventional treatments such as epidurals, pulsed radiofrequency, nerve blocks, and spinal cord stimulation. Antiviral Medications Dr. Rosenblum emphasizes that antiviral drugs should be started within 72 hours of clinical onset, mentioning famciclovir, valacyclovir, and acyclovir. He notes there is no evidence for effectiveness after 72 hours in patients with uncomplicated herpes zoster. Dr. Rosenblum provides dosing information: for immunocompetent patients, famciclovir 500mg and valacyclovir 1000mg three times daily for seven days; for immunocompromised patients, famciclovir 1000mg three times daily for 10 days, while acyclovir should be given IV in the immunocompromised. Benefits of Antiviral Therapy Dr. Rosenblum explains that antiviral medication accelerates the disappearance of vesicles and crusts, promotes healing of skin lesions, and prevents new lesions from forming. By inhibiting viral replication, he notes that antiviral therapy likely reduces nerve damage, resulting in reduced incidence of postherpetic neuralgia, and should be started as soon as possible. Corticosteroids and Opioids Dr. Rosenblum discusses the use of corticosteroids, noting that when added to antiviral medications, they may reduce the severity of acute herpes zoster-related pain, though increased healing of skin lesions was not observed in one study. He mentions that a Cochrane review found oral corticosteroids ineffective in preventing postherpetic neuralgia. Regarding opioids, Dr. Rosenblum states they are commonly used alongside antivirals for controlling acute herpes zoster pain, with tramadol having a number needed to treat (NNT) of 4.7 and strong opioids having an NNT of 4.3 for 50% pain reduction. Methadone and Antidepressants Dr. Rosenblum discusses methadone as an NMDA receptor antagonist used in acute and chronic pain management, though he notes there are no randomized controlled trials determining its efficacy in acute herpes zoster pain or postherpetic neuralgia. He explains that methadone can modulate pain stimuli by inhibiting the uptake of norepinephrine and serotonin, resulting in decreased development of hyperalgesia and opioid tolerance, but has side effects including constipation, nausea, sedation, and QT prolongation that can trigger torsades de pointes. Dr. Rosenblum identifies antidepressants as first-line therapy for postherpetic neuralgia, including tricyclics and SNRIs, with tricyclics having an NNT of 3 and SNRIs an NNT of 6.4 for 50% pain reduction. Antiepileptics and Pharmacological Treatment Summary Dr. Rosenblum discusses antiepileptics like gabapentin and pregabalin for postherpetic neuralgia. He cites two trials measuring gabapentin's effect, concluding it was effective compared to placebo with a pooled NNT of 4.4, while pregabalin had an NNT of 4.9. Dr. Rosenblum summarizes that pharmacological treatment is well established for subacute herpes zoster pain, though new high-quality evidence has been lacking since the last update in 2011. Topical Agents Dr. Rosenblum discusses local anesthetic topical agents including lidocaine and capsaicin creams and patches. He notes that 8% capsaicin provided significant pain reduction during 2-8 weeks, while 5% lidocaine patches provided moderate pain relief after eight weeks of treatment. Dr. Rosenblum also mentions acute herpes zoster intracutaneous injections, citing a study where single intracutaneous injection with methylprednisolone combined with ropivacaine versus saline alone showed significant difference in VAS score at 1 and 4 weeks post-intervention favoring the intervention group. Intracutaneous Injections Dr. Rosenblum discusses the effect of repetitive intracutaneous injections with ropivacaine and methylprednisolone every 48 hours for one week. He cites a randomized control trial comparing antivirals plus analgesics to antivirals plus analgesics and repeat injections, finding the intervention group had significantly shorter duration of pain, lower VAS scores, and lower incidence of postherpetic neuralgia (6.4% vs 28% at 3 months). Dr. Rosenblum notes that a potential side effect of cutaneous methylprednisolone injection is fat atrophy, though this wasn't reported in the study. Summary of Local Anesthetics Dr. Rosenblum summarizes that there are no new studies reporting the efficacy of capsaicin 8% for postherpetic neuralgia, but it remains widely used in clinical practice and is approved in several countries. He notes that lidocaine patches can reduce pain intensity in patients with postherpetic neuralgia but may be more beneficial in patients with allodynia. Dr. Rosenblum adds that intracutaneous injections may be helpful for short periods, while repetitive injections with local anesthetics may reduce VAS scores for up to six months but can cause subcutaneous fat atrophy. Interventional Treatments: Epidural and Paravertebral Injections Dr. Rosenblum discusses interventional treatments, noting that previous guidelines found epidural injection with corticosteroids and local anesthetic as add-on therapy superior to standard care alone for up to one month in managing acute herpes zoster pain. He mentions a randomized controlled trial showing no difference between interlaminar and transforaminal epidural steroid injections for up to three months after the procedure. Dr. Rosenblum adds that previous guidelines reported high-quality evidence that paravertebral injections of corticosteroids or local anesthetic reduces pain in the active phase of herpes zoster. Comparative Studies on Injection Approaches Dr. Rosenblum discusses a trial comparing efficacy of repetitive paravertebral blocks with ropivacaine versus dexmedetomidine to prevent postherpetic neuralgia, which showed significantly lower incidence of zoster-related pain one month after therapy in the dexmedetomidine group, with effects still significant at three months. He also mentions a study comparing steroid injections administered via interlaminar versus transforaminal approaches, finding both groups had significantly lower VAS scores at 1 and 3 months follow-up compared to baseline, though this could align with the natural course of herpes zoster. Timing of Interventions and Continuous Epidural Blockade Dr. Rosenblum cites a retrospective study showing that transforaminal epidural injections administered for acute herpes zoster-related pain were associated with significantly shorter time to pain relief compared to those performed in the subacute phase. He also mentions a randomized controlled trial finding that continuous epidural blockade combined with opioids and gabapentin reduced NRS pain scores more than analgesic drug treatments alone during three-day follow-up, though both studies were low-quality. Interventions for Postherpetic Neuralgia Dr. Rosenblum discusses interventions specifically for postherpetic neuralgia, citing a small randomized controlled trial that demonstrated decreased NRS pain scores six months post-treatment for repeat versus single epidural steroid injections (15mg vs 5mg dexamethasone) administered over 24 days. The trial also found increased likelihood of complete remission during 6-month follow-up in the group receiving repeat epidural dexamethasone, though this was low-quality evidence. Summary of Epidural and Paravertebral Injections Dr. Rosenblum summarizes that epidural or paravertebral injections of local anesthetic and/or glucocorticoids could be considered in treating acute herpes zoster-related pain. For subacute postherpetic neuralgia pain, he notes low-quality evidence supporting epidural injections, while for postherpetic neuralgia, evidence supports continuous epidural infusion, though also of low quality. Dr. Rosenblum emphasizes that none of the included studies for postherpetic neuralgia investigating epidural or paravertebral injections resulted in decreased pain compared to standard therapy. Pulsed Radiofrequency (PRF) Evidence Dr. Rosenblum discusses pulsed radiofrequency (PRF), noting that previous guidelines indicated moderate quality evidence that PRF of the intercostal nerve reduces pain for 6 months in patients with postherpetic neuralgia, and very low-quality evidence that PRF to the dorsal root ganglion (DRG) reduces pain for 6 months. He mentions that multiple studies have been published since then assessing PRF efficacy. PRF Studies for Acute Herpes Zoster Dr. Rosenblum discusses a randomized controlled trial with 60 patients comparing high-voltage bipolar PRF of the cervical sympathetic chain versus sham, with treatment repeated after three days in both groups. He reports that VAS scores in the PRF group at each post-interventional point (1 day, 2 days, 1 month, 2 months, 3 months) were significantly lower than in the sham group, and at 3 months, the incidence of postherpetic neuralgia was 16.7% in the PRF group compared to 40% in the sham group. PRF for Trigeminal Neuralgia Dr. Rosenblum cites another randomized controlled trial evaluating high-voltage long-duration PRF of the Gasserian ganglion in 96 patients with subacute herpes-related trigeminal neuralgia, which found decreased VAS pain scores at all post-interventional time points (3, 7, 14 days and 1, 3, and 6 months) compared to the sham group. He also mentions a randomized comparative effectiveness study in 120 patients with subacute trigeminal herpes zoster, comparing a single application of high-voltage PRF to the Gasserian ganglion versus three cycles of conventional PRF treatment, finding significantly lower mean VAS pain scores for up to six months in the high-voltage PRF group. PRF Compared to Other Interventions Dr. Rosenblum discusses a randomized controlled trial comparing PRF to short-term spinal cord stimulation, which found decreased pain and improved 36-item short-form health survey scores in both groups at six months. He also mentions a randomized controlled trial in 72 patients where PRF of spinal nerves or peripheral branches of cranial nerves combined with five-day infusion of IV lidocaine resulted in greater pain reduction, less rescue analgesia, and reduced inflammatory cytokines at two months compared to PRF with saline infusions. Dr. Rosenblum notes a major limitation of this study was not accounting for the high natural recovery rate. Summary of PRF and Final Recommendations Dr. Rosenblum summarizes that PRF provides significant pain relief lasting over three months in patients with subacute herpes zoster and postherpetic neuralgia. He notes that since few studies have compared PRF versus sham, it's not possible to calculate an accurate number needed to treat. Dr. Rosenblum mentions there are no comparative studies comparing PRF to the intercostal nerves versus PRF of the DRG, but both preclinical and clinical studies suggest superiority of the DRG approach. He adds that evidence for spinal cord stimulation for postherpetic neuralgia is of low quality, and more research is needed given its invasive nature. Sympathetic Blocks and Conclusion Dr. Rosenblum notes there is low-quality evidence for using sympathetic blocks to treat acute herpes zoster-related pain, but no evidence for their use in postherpetic neuralgia. He mentions that risks of treatment with intrathecal methylprednisolone are unclear and therefore not recommended. Dr. Rosenblum concludes by praising the comprehensive article he's been discussing and mentions it provides insight for treating his patients, including a recent case of trigeminal postherpetic neuralgia. Personal Clinical Approach and Closing Dr. Rosenblum shares that he doesn't currently perform PRF in his practice, partly because it's not standard of care and not well reimbursed, creating barriers to implementation. However, he notes that PRF is a very safe procedure as it doesn't involve burning tissue. For his patient with trigeminal neuralgia pain, Dr. Rosenblum plans to try a topical sphenopalatine ganglion block as the least invasive intervention before considering injecting the trigeminal nerves at the foramen, in addition to pharmacotherapy. He concludes by thanking listeners, encouraging them to check the show notes and links, mentioning institutional memberships and shadowing opportunities, and asking listeners to rate and share the podcast. Q&A No Q&A session in this lecture Pain Management Board Prep Ultrasound Training REGISTER TODAY! Create an Account and get Free Access to the PainExam- NRAP Academy Community Highlights David Rosenblum, MD, currently serves as the Director of Pain Management at Maimonides Medical Center and AABP Integrative Pain Care. As a member of the Department of Anesthesiology, he is involved in teaching, research, CME activities, and was key faculty in developing the anesthesiology residency's regional anesthesia block rotation, as well as institutional wide acute and chronic pain management protocols to ensure safe and effective pain management. He currently is a managing partner in a multi-physician private pain practice, AABP Integrative Pain Care, located in Brooklyn, NY. He is one of the earliest interventional pain physicians to integrate ultrasound guidance to improve the safety and accuracy of interventional pain procedures. Awards New York Magazine: Top Doctors: 2016, 2017, 2018, 2021, 2022, 2023, 2024, 2025 Schneps Media: 2015, 2016, 2017, 2019, 2020 Top Doctors New York Metro Area (digital guide): 2016, 2017, 2018, 2019, 2020, 2021, 2022, 2023 2025 Schneps Media - Brooklyn Courier Life: 2021, 2022, 2023 Dr. Rosenblum written several book chapters on Peripheral Neuromodulation, Radiofrequency Ablation, and Pharmacology. He has published numerous noteworthy articles and most recently is developing the ASIPP Guidelines for Peripheral Neuromodulation in the treatment of chronic pain. He has been named several times in NY Magazine's Best Pain Management Doctor List, Nassau County's Best Pain Physician, has appeared on NY1 News, and has made several appearances on XM Radio's Doctor Talk. He currently is lecturing on a national and international level and has partnered with the American Society of Interventional Pain Physicians (ASIPP), American Society of Pain and Neuroscience (ASPN), IASP Mexican Chapter, Eastern Pain Association (EPA), the North American Neuromodulation Society (NANS), World Academy of Pain Medicine United, as well as various other organizations, to support educational events and develop new courses. Since 2008, he has helped over 3000 physicians pass the Pain Management Boards, and has been at the forefront of utilizing ultrasound guidance to perform pain procedures. He now hosts the PainExam podcast, AnesthesiaExam Podcast, PMRExam Podcasts and uses this platform to promote the safe and effective use of ultrasound in the performance of various procedures such as Peripheral Nerve Stimulation, Caudal Epidurals, Selective Nerve Root Blocks, Cluneal Nerve Blocks, Ganglion impar Blocks, Stellate Ganglion Blocks, Brachial Plexus Blocks, Joint Injections and much more! Doctor Rosenblum created the NRAP (Neuromodulation Regional Anesthesia and Pain) Academy and travels to teach various courses focused on Pain Medicine, Regenerative Medicine, Ultrasound Guided Pain Procedures and Regional Anesthesia Techniques. Dr. Rosenblum is persistent when it comes to eliminating pain and has gained a reputation among his patients for thinking "outside the box" and implements ultrasound guidance to deposit medications, biologics (PRP, Bone Marrow Aspirate, etc.) and Peripheral Nerve Stimulators near pain generators. He is currently treating patients in his great neck and Brooklyn office. For an appointment go to AABPpain.com or call Brooklyn 718 436 7246 Reference Adriaansen, E. J., Jacobs, J. G., Vernooij, L. M., van Wijck, A. J., Cohen, S. P., Huygen, F. J., & Rijsdijk, M. (2025). 8. Herpes zoster and post herpetic neuralgia. Pain Practice, 25(1), e13423.
Summary In this episode of the Pain Exam Podcast, Dr. David Rosenblum provides a comprehensive review of herpes zoster and postherpetic neuralgia (PHN), focusing on pathophysiology, diagnosis, and treatment options. Dr. Rosenblum explains that postherpetic neuralgia affects approximately 25% of patients with acute herpes zoster, causing debilitating unilateral chronic pain in one or more dermatomes. He discusses the three phases of herpes zoster: acute (up to 30 days), subacute (up to 3 months), and postherpetic neuralgia (pain continuing beyond 3 months). Dr. Rosenblum identifies risk factors for developing PHN, including older age, female sex, immunosuppression, prodromal pain, severe rash, and greater acute pain severity. He details the pathophysiology involving peripheral and central sensitization, and explains different phenotypes of PHN that can guide treatment approaches. For treatment, Dr. Rosenblum reviews various options including antiviral medications (which should be started within 72 hours of onset), corticosteroids, opioids, antidepressants (particularly tricyclics and SNRIs), antiepileptics (gabapentin and pregabalin), topical agents (lidocaine and capsaicin), and interventional procedures such as epidural injections and pulsed radiofrequency. He emphasizes that prevention through vaccination with Shingrix is highly effective, with 97% effectiveness in preventing herpes zoster in patients 50-69 years old and 89% effectiveness in those over 70. Dr. Rosenblum mentions that he's currently treating a patient with trigeminal postherpetic neuralgia and is considering a topical sphenopalatine ganglion block as a minimally invasive intervention before attempting more invasive procedures. Chapters Introduction to the Pain Exam Podcast and Topic Overview Dr. David Rosenblum introduces the Pain Exam Podcast, mentioning that it covers painful disorders, alternative treatments, and practice management. He explains that this episode focuses on herpes zoster and postherpetic neuralgia as board preparation for fellows starting their programs, with ABA boards coming up in September. Dr. Rosenblum notes that he's not only preparing listeners for boards but also seeking the latest information to help treat his own patients with this notoriously difficult disease. Upcoming Conferences and Educational Opportunities Dr. Rosenblum announces several upcoming conferences including Aspen in July, Pain Week in September, and events with NYSIP and the Latin American Pain Society. He mentions he'll be teaching ultrasound and regenerative medicine at these events. Dr. Rosenblum invites listeners to sign up at nrappain.org to access a community discussing regenerative medicine, ultrasound-guided pain medicine, regional anesthesia, and board preparation. He also offers ultrasound training in New York and elsewhere, with upcoming sessions in Manhattan on July 12th and October 4th, plus private shadowing opportunities. Overview of Postherpetic Neuralgia Dr. Rosenblum defines postherpetic neuralgia as typically a unilateral chronic pain in one or more dermatomes after acute herpes zoster infection. He states that the incidence of acute herpes zoster ranges between 3-5 patients per thousand person-years, and one in four patients with acute herpes zoster-related pain will transition into postherpetic neuralgia. Dr. Rosenblum emphasizes that while this condition won't kill patients, it can be extremely debilitating and significantly reduce quality of life. Treatment Options Overview Dr. Rosenblum reviews treatment options according to the WHO pain ladder, including tricyclics like nortriptyline and antiepileptic drugs such as gabapentin. He explains that if pain is not significantly reduced, interventional treatments like epidural injections with local anesthetics and corticosteroids or pulsed radiofrequency of the dorsal root ganglion are options. For postherpetic neuralgia specifically, Dr. Rosenblum notes that preferred treatments include transdermal capsaicin, lidocaine, or oral drugs such as antidepressants or antiepileptics. Phases of Herpes Zoster and Definitions Dr. Rosenblum outlines the three phases during herpes zoster reactivation: acute herpes zoster-related pain (lasting maximum 30 days), subacute herpes zoster-related pain (pain after healing of vesicles but disappearing within 3 months), and postherpetic neuralgia (typically defined as pain continuing after 3 months). He mentions that acute herpes zoster pain often begins with prodromal pain starting a few days before the appearance of the rash. Incidence and Risk Factors Dr. Rosenblum states that the incidence of herpes zoster ranges between 3-5 patients per 1,000 person-years, with approximately 5-30% of cases leading to postherpetic neuralgia. He identifies risk factors including older age, female sex, immunosuppression, prodromal pain, severe rash, and greater acute pain severity. Dr. Rosenblum describes the clinical manifestations as a mosaic of somatosensory symptoms including burning, deep aching pain, tingling, itching, stabbing, often associated with tactile and cold allodynia. Impact on Quality of Life Dr. Rosenblum emphasizes that postherpetic neuralgia can be debilitating, impacting both physical and emotional functioning and causing decreased quality of life. He notes that it leads to fatigue, insomnia, depression, anorexia, anxiety, and emotional distress. Dr. Rosenblum stresses the importance of exploring methods for prevention of postherpetic neuralgia and optimizing pain treatment for both subacute herpes zoster-related pain and postherpetic neuralgia. Literature Review and Pathophysiology Dr. Rosenblum mentions that he's discussing a literature review from 2024 that updates previous practical guidelines published in 2011. He explains the pathophysiology of postherpetic neuralgia, which involves sensitization of peripheral and sensory nerves from damage. Dr. Rosenblum describes how inflammatory mediators reduce the stimulus threshold of nociceptors and increase responsiveness, resulting in pathological spontaneous discharges, lower thresholds for thermal and mechanical stimuli, and hyperalgesia. Central Sensitization and Nerve Damage Dr. Rosenblum explains that central sensitization results from peripheral nociceptor hyperactivity leading to plastic changes in the central nervous system, involving amplification of pain signals and reduced inhibition. He describes how nerve damage in postherpetic neuralgia patients results from neuronal death due to severe inflammatory stimuli or secondary to neuronal swelling. Dr. Rosenblum notes that motor defects occur in 0.05% of patients with herpes zoster, observed as abdominal pseudohernias or motor weakness of limbs limited to the affected myotome. Different Phenotypes and Classification Dr. Rosenblum discusses different phenotypes of postherpetic neuralgia and how phenotyping can determine treatment. He explains that there are several ways to classify the phenotypes, with one categorizing patients into three subtypes: sensory loss (most common), thermal gain, and thermal loss with mechanical gain. Dr. Rosenblum describes the mechanistic categorization, including the irritable nociceptive phenotype characterized by preserved sensation, profound dynamic mechanical allodynia, reduced pressure pain threshold, and relief with local anesthetic infiltration. Deafferentation Phenotype Dr. Rosenblum explains that a deafferentation phenotype may arise from destruction of neurons by the virus in the dorsal root ganglion. This phenotype is characterized by sensory loss, including thermal and vibratory sensation without prominent thermal allodynia. He notes that mechanical allodynia can occur secondary to A-beta fibers activating spinothalamic pathways (known as phenotypic switches), along with pressure hyperalgesia and temporal summation suggesting central sensitization. Dr. Rosenblum mentions that in one study, this phenotype was present in 10.8% of individuals, and for those with deafferentation pain, gabapentinoids, antidepressants, and neuromodulatory therapies like repetitive transcranial magnetic stimulation may be beneficial. Diagnosis and Physical Examination Dr. Rosenblum discusses the diagnosis of herpes zoster and postherpetic neuralgia, emphasizing the importance of physical examination. He explains that diagnosis is based on the rash, redness, papules, and vesicles in the painful dermatomes, with healing vesicles showing crust formation. Dr. Rosenblum notes that the rash is generally unilateral and does not cross the midline of the body. In postherpetic neuralgia patients, he mentions that scarring, hyper or hypopigmentation is often visible, with allodynia present in 45-75% of affected patients. Sensory Testing and Assessment Dr. Rosenblum explains that in patients with postherpetic neuralgia, a mosaic of somatosensory alterations can occur, manifesting as hyperalgesia, allodynia, and sensory loss. These can be quantified by quantitative sensory testing, which assesses somatosensory functions, dermal detection thresholds for perception of cold, warmth, and paradoxical heat sensations. He notes that testing can provide clues regarding underlying mechanisms of pain, impaired conditioned pain modulation, temporal summation suggesting central sensitization, and information about the type of nerve damage and surviving afferent neurons. Prevention Through Vaccination Dr. Rosenblum discusses prevention of acute herpes zoster through vaccination, noting that the risk increases with reduced immunity. He highlights studies evaluating Shingrix, a vaccine for herpes zoster, which showed 97% effectiveness in preventing herpes zoster in patients 50-69 years old with healthy immune systems and 89% effectiveness in patients over 70. Dr. Rosenblum states that Shingrix is 89-91% effective in preventing postherpetic neuralgia development in patients with healthy immune systems and 68-91% effective in those with weakened or underlying conditions. Treatment Objectives Dr. Rosenblum outlines the treatment objectives for herpes zoster and postherpetic neuralgia. For acute herpes zoster, objectives include relieving pain, reducing severity and duration of pain, accelerating recovery of epidermal defects, and preventing secondary infections. For postherpetic neuralgia, the objectives are pain alleviation and improved quality of life. Dr. Rosenblum lists available treatments including psychotherapy, opiates, antidepressants, antiepileptics, NMDA antagonists, topical agents, and interventional treatments such as epidurals, pulsed radiofrequency, nerve blocks, and spinal cord stimulation. Antiviral Medications Dr. Rosenblum emphasizes that antiviral drugs should be started within 72 hours of clinical onset, mentioning famciclovir, valacyclovir, and acyclovir. He notes there is no evidence for effectiveness after 72 hours in patients with uncomplicated herpes zoster. Dr. Rosenblum provides dosing information: for immunocompetent patients, famciclovir 500mg and valacyclovir 1000mg three times daily for seven days; for immunocompromised patients, famciclovir 1000mg three times daily for 10 days, while acyclovir should be given IV in the immunocompromised. Benefits of Antiviral Therapy Dr. Rosenblum explains that antiviral medication accelerates the disappearance of vesicles and crusts, promotes healing of skin lesions, and prevents new lesions from forming. By inhibiting viral replication, he notes that antiviral therapy likely reduces nerve damage, resulting in reduced incidence of postherpetic neuralgia, and should be started as soon as possible. Corticosteroids and Opioids Dr. Rosenblum discusses the use of corticosteroids, noting that when added to antiviral medications, they may reduce the severity of acute herpes zoster-related pain, though increased healing of skin lesions was not observed in one study. He mentions that a Cochrane review found oral corticosteroids ineffective in preventing postherpetic neuralgia. Regarding opioids, Dr. Rosenblum states they are commonly used alongside antivirals for controlling acute herpes zoster pain, with tramadol having a number needed to treat (NNT) of 4.7 and strong opioids having an NNT of 4.3 for 50% pain reduction. Methadone and Antidepressants Dr. Rosenblum discusses methadone as an NMDA receptor antagonist used in acute and chronic pain management, though he notes there are no randomized controlled trials determining its efficacy in acute herpes zoster pain or postherpetic neuralgia. He explains that methadone can modulate pain stimuli by inhibiting the uptake of norepinephrine and serotonin, resulting in decreased development of hyperalgesia and opioid tolerance, but has side effects including constipation, nausea, sedation, and QT prolongation that can trigger torsades de pointes. Dr. Rosenblum identifies antidepressants as first-line therapy for postherpetic neuralgia, including tricyclics and SNRIs, with tricyclics having an NNT of 3 and SNRIs an NNT of 6.4 for 50% pain reduction. Antiepileptics and Pharmacological Treatment Summary Dr. Rosenblum discusses antiepileptics like gabapentin and pregabalin for postherpetic neuralgia. He cites two trials measuring gabapentin's effect, concluding it was effective compared to placebo with a pooled NNT of 4.4, while pregabalin had an NNT of 4.9. Dr. Rosenblum summarizes that pharmacological treatment is well established for subacute herpes zoster pain, though new high-quality evidence has been lacking since the last update in 2011. Topical Agents Dr. Rosenblum discusses local anesthetic topical agents including lidocaine and capsaicin creams and patches. He notes that 8% capsaicin provided significant pain reduction during 2-8 weeks, while 5% lidocaine patches provided moderate pain relief after eight weeks of treatment. Dr. Rosenblum also mentions acute herpes zoster intracutaneous injections, citing a study where single intracutaneous injection with methylprednisolone combined with ropivacaine versus saline alone showed significant difference in VAS score at 1 and 4 weeks post-intervention favoring the intervention group. Intracutaneous Injections Dr. Rosenblum discusses the effect of repetitive intracutaneous injections with ropivacaine and methylprednisolone every 48 hours for one week. He cites a randomized control trial comparing antivirals plus analgesics to antivirals plus analgesics and repeat injections, finding the intervention group had significantly shorter duration of pain, lower VAS scores, and lower incidence of postherpetic neuralgia (6.4% vs 28% at 3 months). Dr. Rosenblum notes that a potential side effect of cutaneous methylprednisolone injection is fat atrophy, though this wasn't reported in the study. Summary of Local Anesthetics Dr. Rosenblum summarizes that there are no new studies reporting the efficacy of capsaicin 8% for postherpetic neuralgia, but it remains widely used in clinical practice and is approved in several countries. He notes that lidocaine patches can reduce pain intensity in patients with postherpetic neuralgia but may be more beneficial in patients with allodynia. Dr. Rosenblum adds that intracutaneous injections may be helpful for short periods, while repetitive injections with local anesthetics may reduce VAS scores for up to six months but can cause subcutaneous fat atrophy. Interventional Treatments: Epidural and Paravertebral Injections Dr. Rosenblum discusses interventional treatments, noting that previous guidelines found epidural injection with corticosteroids and local anesthetic as add-on therapy superior to standard care alone for up to one month in managing acute herpes zoster pain. He mentions a randomized controlled trial showing no difference between interlaminar and transforaminal epidural steroid injections for up to three months after the procedure. Dr. Rosenblum adds that previous guidelines reported high-quality evidence that paravertebral injections of corticosteroids or local anesthetic reduces pain in the active phase of herpes zoster. Comparative Studies on Injection Approaches Dr. Rosenblum discusses a trial comparing efficacy of repetitive paravertebral blocks with ropivacaine versus dexmedetomidine to prevent postherpetic neuralgia, which showed significantly lower incidence of zoster-related pain one month after therapy in the dexmedetomidine group, with effects still significant at three months. He also mentions a study comparing steroid injections administered via interlaminar versus transforaminal approaches, finding both groups had significantly lower VAS scores at 1 and 3 months follow-up compared to baseline, though this could align with the natural course of herpes zoster. Timing of Interventions and Continuous Epidural Blockade Dr. Rosenblum cites a retrospective study showing that transforaminal epidural injections administered for acute herpes zoster-related pain were associated with significantly shorter time to pain relief compared to those performed in the subacute phase. He also mentions a randomized controlled trial finding that continuous epidural blockade combined with opioids and gabapentin reduced NRS pain scores more than analgesic drug treatments alone during three-day follow-up, though both studies were low-quality. Interventions for Postherpetic Neuralgia Dr. Rosenblum discusses interventions specifically for postherpetic neuralgia, citing a small randomized controlled trial that demonstrated decreased NRS pain scores six months post-treatment for repeat versus single epidural steroid injections (15mg vs 5mg dexamethasone) administered over 24 days. The trial also found increased likelihood of complete remission during 6-month follow-up in the group receiving repeat epidural dexamethasone, though this was low-quality evidence. Summary of Epidural and Paravertebral Injections Dr. Rosenblum summarizes that epidural or paravertebral injections of local anesthetic and/or glucocorticoids could be considered in treating acute herpes zoster-related pain. For subacute postherpetic neuralgia pain, he notes low-quality evidence supporting epidural injections, while for postherpetic neuralgia, evidence supports continuous epidural infusion, though also of low quality. Dr. Rosenblum emphasizes that none of the included studies for postherpetic neuralgia investigating epidural or paravertebral injections resulted in decreased pain compared to standard therapy. Pulsed Radiofrequency (PRF) Evidence Dr. Rosenblum discusses pulsed radiofrequency (PRF), noting that previous guidelines indicated moderate quality evidence that PRF of the intercostal nerve reduces pain for 6 months in patients with postherpetic neuralgia, and very low-quality evidence that PRF to the dorsal root ganglion (DRG) reduces pain for 6 months. He mentions that multiple studies have been published since then assessing PRF efficacy. PRF Studies for Acute Herpes Zoster Dr. Rosenblum discusses a randomized controlled trial with 60 patients comparing high-voltage bipolar PRF of the cervical sympathetic chain versus sham, with treatment repeated after three days in both groups. He reports that VAS scores in the PRF group at each post-interventional point (1 day, 2 days, 1 month, 2 months, 3 months) were significantly lower than in the sham group, and at 3 months, the incidence of postherpetic neuralgia was 16.7% in the PRF group compared to 40% in the sham group. PRF for Trigeminal Neuralgia Dr. Rosenblum cites another randomized controlled trial evaluating high-voltage long-duration PRF of the Gasserian ganglion in 96 patients with subacute herpes-related trigeminal neuralgia, which found decreased VAS pain scores at all post-interventional time points (3, 7, 14 days and 1, 3, and 6 months) compared to the sham group. He also mentions a randomized comparative effectiveness study in 120 patients with subacute trigeminal herpes zoster, comparing a single application of high-voltage PRF to the Gasserian ganglion versus three cycles of conventional PRF treatment, finding significantly lower mean VAS pain scores for up to six months in the high-voltage PRF group. PRF Compared to Other Interventions Dr. Rosenblum discusses a randomized controlled trial comparing PRF to short-term spinal cord stimulation, which found decreased pain and improved 36-item short-form health survey scores in both groups at six months. He also mentions a randomized controlled trial in 72 patients where PRF of spinal nerves or peripheral branches of cranial nerves combined with five-day infusion of IV lidocaine resulted in greater pain reduction, less rescue analgesia, and reduced inflammatory cytokines at two months compared to PRF with saline infusions. Dr. Rosenblum notes a major limitation of this study was not accounting for the high natural recovery rate. Summary of PRF and Final Recommendations Dr. Rosenblum summarizes that PRF provides significant pain relief lasting over three months in patients with subacute herpes zoster and postherpetic neuralgia. He notes that since few studies have compared PRF versus sham, it's not possible to calculate an accurate number needed to treat. Dr. Rosenblum mentions there are no comparative studies comparing PRF to the intercostal nerves versus PRF of the DRG, but both preclinical and clinical studies suggest superiority of the DRG approach. He adds that evidence for spinal cord stimulation for postherpetic neuralgia is of low quality, and more research is needed given its invasive nature. Sympathetic Blocks and Conclusion Dr. Rosenblum notes there is low-quality evidence for using sympathetic blocks to treat acute herpes zoster-related pain, but no evidence for their use in postherpetic neuralgia. He mentions that risks of treatment with intrathecal methylprednisolone are unclear and therefore not recommended. Dr. Rosenblum concludes by praising the comprehensive article he's been discussing and mentions it provides insight for treating his patients, including a recent case of trigeminal postherpetic neuralgia. Personal Clinical Approach and Closing Dr. Rosenblum shares that he doesn't currently perform PRF in his practice, partly because it's not standard of care and not well reimbursed, creating barriers to implementation. However, he notes that PRF is a very safe procedure as it doesn't involve burning tissue. For his patient with trigeminal neuralgia pain, Dr. Rosenblum plans to try a topical sphenopalatine ganglion block as the least invasive intervention before considering injecting the trigeminal nerves at the foramen, in addition to pharmacotherapy. He concludes by thanking listeners, encouraging them to check the show notes and links, mentioning institutional memberships and shadowing opportunities, and asking listeners to rate and share the podcast. Q&A No Q&A session in this lecture Pain Management Board Prep Ultrasound Training REGISTER TODAY! Create an Account and get Free Access to the PainExam- NRAP Academy Community Highlights David Rosenblum, MD, currently serves as the Director of Pain Management at Maimonides Medical Center and AABP Integrative Pain Care. As a member of the Department of Anesthesiology, he is involved in teaching, research, CME activities, and was key faculty in developing the anesthesiology residency's regional anesthesia block rotation, as well as institutional wide acute and chronic pain management protocols to ensure safe and effective pain management. He currently is a managing partner in a multi-physician private pain practice, AABP Integrative Pain Care, located in Brooklyn, NY. He is one of the earliest interventional pain physicians to integrate ultrasound guidance to improve the safety and accuracy of interventional pain procedures. Awards New York Magazine: Top Doctors: 2016, 2017, 2018, 2021, 2022, 2023, 2024, 2025 Schneps Media: 2015, 2016, 2017, 2019, 2020 Top Doctors New York Metro Area (digital guide): 2016, 2017, 2018, 2019, 2020, 2021, 2022, 2023 2025 Schneps Media - Brooklyn Courier Life: 2021, 2022, 2023 Dr. Rosenblum written several book chapters on Peripheral Neuromodulation, Radiofrequency Ablation, and Pharmacology. He has published numerous noteworthy articles and most recently is developing the ASIPP Guidelines for Peripheral Neuromodulation in the treatment of chronic pain. He has been named several times in NY Magazine's Best Pain Management Doctor List, Nassau County's Best Pain Physician, has appeared on NY1 News, and has made several appearances on XM Radio's Doctor Talk. He currently is lecturing on a national and international level and has partnered with the American Society of Interventional Pain Physicians (ASIPP), American Society of Pain and Neuroscience (ASPN), IASP Mexican Chapter, Eastern Pain Association (EPA), the North American Neuromodulation Society (NANS), World Academy of Pain Medicine United, as well as various other organizations, to support educational events and develop new courses. Since 2008, he has helped over 3000 physicians pass the Pain Management Boards, and has been at the forefront of utilizing ultrasound guidance to perform pain procedures. He now hosts the PainExam podcast, AnesthesiaExam Podcast, PMRExam Podcasts and uses this platform to promote the safe and effective use of ultrasound in the performance of various procedures such as Peripheral Nerve Stimulation, Caudal Epidurals, Selective Nerve Root Blocks, Cluneal Nerve Blocks, Ganglion impar Blocks, Stellate Ganglion Blocks, Brachial Plexus Blocks, Joint Injections and much more! Doctor Rosenblum created the NRAP (Neuromodulation Regional Anesthesia and Pain) Academy and travels to teach various courses focused on Pain Medicine, Regenerative Medicine, Ultrasound Guided Pain Procedures and Regional Anesthesia Techniques. Dr. Rosenblum is persistent when it comes to eliminating pain and has gained a reputation among his patients for thinking "outside the box" and implements ultrasound guidance to deposit medications, biologics (PRP, Bone Marrow Aspirate, etc.) and Peripheral Nerve Stimulators near pain generators. He is currently treating patients in his great neck and Brooklyn office. For an appointment go to AABPpain.com or call Brooklyn 718 436 7246 Reference Adriaansen, E. J., Jacobs, J. G., Vernooij, L. M., van Wijck, A. J., Cohen, S. P., Huygen, F. J., & Rijsdijk, M. (2025). 8. Herpes zoster and post herpetic neuralgia. Pain Practice, 25(1), e13423.
Ad Verbrugge in gesprek met Annelies Huygen.--Steun DNW en word patroon op http://www.petjeaf.com/denieuwewereld.Liever direct overmaken? Maak dan uw gift over naar NL61 RABO 0357 5828 61 t.n.v. Stichting De Nieuwe Wereld. Crypto's doneren kan via https://commerce.coinbase.com/pay/79870e0f-f817-463e-bde7-a5a8cb08c09f-- Bronnen en links bij deze uitzending: - Een eerder gesprek met Annelies Huygen: https://www.youtube.com/watch?v=94FbqPXgzy0 en nog een: https://www.youtube.com/watch?v=FPXpp6at3NE- De afscheidsrede van Annelies Huygen: https://energiesamen.blob.core.windows.net/media/190225_Afscheidsrede%20Annelies%20Huygen.pdf--00:00 Introductie00:35 Stroomstoring in Spanje en Portugal4:25 Elektriciteit, decentralisatie, technologische afhankelijkheid24:30 Schaalvergroting en privatisering38:50 Onkunde bij overheid--De Nieuwe Wereld TV is een platform dat mensen uit verschillende disciplines bij elkaar brengt om na te denken over grote veranderingen die op komst zijn door een combinatie van snelle technologische ontwikkelingen en globalisering. Het is een initiatief van filosoof Ad Verbrugge in samenwerking met anchors Jelle van Baardewijk en Marlies Dekkers. De Nieuwe Wereld TV wordt gemaakt in samenwerking met de Filosofische School Nederland. Onze website: https://denieuwewereld.tv/ DNW heeft ook een Substack. Meld je hier aan: https://denieuwewereld.substack.com/
HOUR ONE: More than a hundred years ago, reports described it as “the most weird and gruesome apartment in the world.” Why display an entire room full of grotesque items and open it to the public? (New York Charnel House) *** Kell's Irish Pub in Seattle has a creepy vibe to it, even if the displays and decorations inside aren't meant to be. Perhaps that's because the building started its life as a massive mortuary. (The Beaux Arts Butterworth Building) *** Early one February morning in 1897, John Mars jumped out of bed from a sound sleep, and while the smell of breakfast cooking downstairs wafted up to the second level of the house, he inexplicably grabbed his pistol and went on a shooting spree of his own family. (The Act of a Mad Man) *** A four-year-old has a paranormal experience… and the man he grew into over 60 years later is still unsure of what happened to him. (The Lady Laughing In My Bedroom)==========HOUR TWO: A Malaysian Haunted House To Sell *** The brutal death of an African slave brings a curse upon the wooden chest he was ordered to construct. (The Conjure Chest) *** In Tuscaloosa, Alabama there is a home built by slaves that is considered the most haunted in Alabama. (The Haunting of Drish House) *** Drivers are reporting strange, ghostly orbs following them on dark roads. (Haunted Roads and Spook Lights) ==========SUDDEN DEATH OVERTIME: Dang Tan Ngoc is a well-known conman who has used the names of multiple dead soldiers to con veteran groups into giving him money. One identity he stole created a fascinating but dark story. (The Strange Return Of Master Sgt. John Hartley Robertson) *** A woman comes home to find her visiting sister murdered – and police were convinced she was the one who committed the crime. So what went wrong with the case to allow her to get away with it? (Did Ida Do It?) *** A bordello, pizza, and a haunting. You can find them all at the Red Onion Saloon. (Red Onion Saloon) *** Plus, I'll share two Creepypastas from Weirdo family members. “A Brief History of Egberting” from Louise Latham, and “Dreamality“ from Kara Raisch.==========SOURCES AND REFERENCES FROM TONIGHT'S SHOW:“The Lady Laughing In My Bedroom” by Geof James: (link no longer available)“New York Charnel House”: (site no longer exists)“The Beaux Arts Butterworth Building” by Meg van Huygen: https://tinyurl.com/y7h2mkyr“The Act of a Madman” by Robert Wilhelm: https://tinyurl.com/y9757b7d“A Malaysian Haunted House to Sell” by Brandon Grimes for Paranormality Magazine: (site no longer exists)“The Conjure Chest” for The Unexplained Mysteries: https://tinyurl.com/m9w2ffg“The Haunting of Drish House” by Amanda Penn for Horror Media: (site no longer exists)“Haunted Roads and Spook Lights” by Brent Swancer for Mysterious Universe: https://tinyurl.com/ydfwg875“The Strange Return Of Master Sgt. John Hartley Robertson” by Derek Faraci for The 13th Floor: (site no longer exists)“Did Ida Do It?” by Robert Wilhelm for Murder By Gaslight: https://tinyurl.com/yamhvs69“The Red Onion Saloon” by Amanda Penn for Horror Media: (site no longer exists)==========(Over time links seen above may become invalid, disappear, or have different content. I always make sure to give authors credit for material I use whenever possible. If I have overlooked doing so for a story, or if a credit is incorrect, please let me know and I will rectify it immediately. Some links may benefit me financially through qualifying purchases.)=========="I have come into the world as a light, so that no one who believes in me should stay in darkness." — John 12:46==========WeirdDarkness®, WeirdDarkness© 2025==========To become a Weird Darkness Radio Show affiliate, contact Radio America at affiliates@radioamerica.com, or call 800-807-4703 (press 2 or dial ext 250).
Jules Kleedt Uit - Aflevering 21. Speciale gast Tijl Huygen gaat in gesprek met Jules Tielens over het zeer specifieke onderwerp: Gevangenispsychiatrie.
Ad Verbrugge in gesprek met journalist en bestuurslid van Beter Onderwijs Nederland Felix Huygen over de voorgenomen bezuinigingen op het hoger onderwijs. -- Steun De Nieuwe Wereld en doe mee aan onze eindejaarsactie: http://gofundme.com/dnw2024. Liever direct overmaken? Maak dan uw gift over naar NL61 RABO 0357 5828 61 t.n.v. Stichting De Nieuwe Wereld. Patroon worden kan op http://www.petjeaf.com/denieuwewereld. -- Bronnen en links bij deze uitzending: - De website van Beter Onderwijs Nederland: https://www.beteronderwijsnederland.nl/ - Bestel hier 'Waartoe is de universiteit op aarde': https://www.boom.nl/geschiedenis/100-1213_Waartoe-is-de-universiteit-op-aarde
Darkness Syndicate members get the ad-free version: https://weirddarkness.tiny.us/2p8thfeuIN THIS EPISODE: More than a hundred years ago, reports described it as “the most weird and gruesome apartment in the world.” Why display an entire room full of grotesque items and open it to the public? (New York Charnel House) *** Kell's Irish Pub in Seattle has a creepy vibe to it, even if the displays and decorations inside aren't meant to be. Perhaps that's because the building started its life as a massive mortuary. (The Beaux Arts Butterworth Building) *** Early one February morning in 1897, John Mars jumped out of bed from a sound sleep, and while the smell of breakfast cooking downstairs wafted up to the second level of the house, he inexplicably grabbed his pistol and went on a shooting spree of his own family. (The Act of a Mad Man) *** A four-year-old has a paranormal experience… and the man he grew into over 60 years later is still unsure of what happened to him. (The Lady Laughing In My Bedroom)CHAPTERS & TIME STAMPS (All Times Approximate)…00:00:00.000 = Show Open00:02:28.890 = The Lady Laughing In My Bedroom00:14:52.544 = New York Charnel House00:28:50.792 = The Beaux Arts Butterworth Building00:38:49.139 = The Act of a Madman00:43:10.098 = Show CloseSOURCES AND REFERENCES FROM THE EPISODE…“The Lady Laughing In My Bedroom” by Geof James: https://tinyurl.com/yd4uddnx“New York Charnel House”: (link no longer valid)“The Beaux Arts Butterworth Building” by Meg van Huygen: https://tinyurl.com/y7h2mkyr“The Act of a Madman” by Robert Wilhelm: https://tinyurl.com/y9757b7dWeird Darkness theme by Alibi Music Library.= = = = =(Over time links seen above may become invalid, disappear, or have different content. I always make sure to give authors credit for the material I use whenever possible. If I somehow overlooked doing so for a story, or if a credit is incorrect, please let me know and I will rectify it in these show notes immediately. Some links included above may benefit me financially through qualifying purchases.)= = = = ="I have come into the world as a light, so that no one who believes in me should stay in darkness." — John 12:46= = = = =WeirdDarkness® is a registered trademark. Copyright ©2024, Weird Darkness.= = = = =Originally aired: June 12, 2023CUSTOM LANDING PAGE: https://weirddarkness.com/theladylaughing
WE ARE BACK!!! New Co-Hosts, New Segments, and now featuring our studio band, Dave Matthews playing electronic dance music (EDMB)
HOUR ONE: A Malaysian Haunted House To Sell *** The brutal death of an African slave brings a curse upon the wooden chest he was ordered to construct. (The Conjure Chest) *** In Tuscaloosa, Alabama there is a home built by slaves that is considered the most haunted in Alabama. (The Haunting of Drish House) *** Drivers are reporting strange, ghostly orbs following them on dark roads. (Haunted Roads and Spook Lights) ==========HOUR TWO: More than a hundred years ago, reports described it as “the most weird and gruesome apartment in the world.” Why display an entire room full of grotesque items and open it to the public? (New York Charnel House) *** Kell's Irish Pub in Seattle has a creepy vibe to it, even if the displays and decorations inside aren't meant to be. Perhaps that's because the building started its life as a massive mortuary. (The Beaux Arts Butterworth Building) *** Early one February morning in 1897, John Mars jumped out of bed from a sound sleep, and while the smell of breakfast cooking downstairs wafted up to the second level of the house, he inexplicably grabbed his pistol and went on a shooting spree of his own family. (The Act of a Mad Man) *** A four-year-old has a paranormal experience… and the man he grew into over 60 years later is still unsure of what happened to him. (The Lady Laughing In My Bedroom)==========SUDDEN DEATH OVERTIME: Dang Tan Ngoc is a well-known conman who has used the names of multiple dead soldiers to con veteran groups into giving him money. One identity he stole created a fascinating but dark story. (The Strange Return Of Master Sgt. John Hartley Robertson) *** A woman comes home to find her visiting sister murdered – and police were convinced she was the one who committed the crime. So what went wrong with the case to allow her to get away with it? (Did Ida Do It?) *** A bordello, pizza, and a haunting. You can find them all at the Red Onion Saloon. (Red Onion Saloon) *** Plus, I'll share two Creepypastas from Weirdo family members. “A Brief History of Egberting” from Louise Latham, and “Dreamality“ from Kara Raisch.==========SOURCES AND REFERENCES FROM TONIGHT'S SHOW:“The Lady Laughing In My Bedroom” by Geof James: https://tinyurl.com/yd4uddnx“New York Charnel House” posted at: https://tinyurl.com/ybsfs68x“The Beaux Arts Butterworth Building” by Meg van Huygen: https://tinyurl.com/y7h2mkyr“The Act of a Madman” by Robert Wilhelm: https://tinyurl.com/y9757b7d“A Malaysian Haunted House to Sell” by Brandon Grimes for Paranormality Magazine: http://weirddarkness.com/magazine“The Conjure Chest” for The Unexplained Mysteries: https://tinyurl.com/m9w2ffg“The Haunting of Drish House” by Amanda Penn for Horror Media: https://tinyurl.com/y8bovtwp“Haunted Roads and Spook Lights” by Brent Swancer for Mysterious Universe: https://tinyurl.com/ydfwg875“The Strange Return Of Master Sgt. John Hartley Robertson” by Derek Faraci for The 13th Floor: (site no longer exists)“Did Ida Do It?” by Robert Wilhelm for Murder By Gaslight: https://tinyurl.com/yamhvs69“The Red Onion Saloon” by Amanda Penn for Horror Media: https://tinyurl.com/y7te6wqe==========(Over time links seen above may become invalid, disappear, or have different content. I always make sure to give authors credit for material I use whenever possible. If I have overlooked doing so for a story, or if a credit is incorrect, please let me know and I will rectify it immediately. Some links may benefit me financially through qualifying purchases.)=========="I have come into the world as a light, so that no one who believes in me should stay in darkness." — John 12:46==========WeirdDarkness®, WeirdDarkness© 2024==========To become a Weird Darkness Radio Show affiliate, contact Radio America at affiliates@radioamerica.com, or call 800-807-4703 (press 2 or dial ext 250).
In deze aflevering spreken met een zeer gewaardeerde collega Tijl Huygen. Tijl is een door de wol geverfde psychiater die zijn hele leven in en rondom gevangenissen en in een forensische setting heeft gewerkt. Vanuit zijn ervaring, maar ook zijn uitgebreide wetenschappelijke kennis, bespreken we wat een psychopaat tot psychopaat maakt. Welke soort het psychopaten we kunnen onderscheiden en hoe deze te herkennen zijn en heel belangrijk hoe moeten daarmee omgaan. Met name hoe gaan we daarmee om wanneer we er op een de dag mee te maken krijgen. Hierbij bijvoorbeeld te denken aan teams in gevangenissen of in een forensische setting. Wat doen psychopaten met ons en wat doen wij eigenlijk met hen. Creëren zij rollen voor ons of doen we daar net zo hard aan mee? Kortom weer een boeiende uitzending over deze bijzondere kant van de psychiatrie waar we toch eigenlijk maar weinig over horen. JULES KLEEDT UIT Presentatie: JULES TIELENS, met tafeldames Lieke & Pip Meer informatie en boekingen: www.juleskleedtuit.nl
HOUR ONE: More than a hundred years ago, reports described it as “the most weird and gruesome apartment in the world.” Why display an entire room full of grotesque items and open it to the public? (New York Charnel House) *** Kell's Irish Pub in Seattle has a creepy vibe to it, even if the displays and decorations inside aren't meant to be. Perhaps that's because the building started its life as a massive mortuary. (The Beaux Arts Butterworth Building) *** Early one February morning in 1897, John Mars jumped out of bed from a sound sleep, and while the smell of breakfast cooking downstairs wafted up to the second level of the house, he inexplicably grabbed his pistol and went on a shooting spree of his own family. (The Act of a Mad Man) *** A four-year-old has a paranormal experience… and the man he grew into over 60 years later is still unsure of what happened to him. (The Lady Laughing In My Bedroom)==========HOUR TWO: A Malaysian Haunted House To Sell *** The brutal death of an African slave brings a curse upon the wooden chest he was ordered to construct. (The Conjure Chest) *** In Tuscaloosa, Alabama there is a home built by slaves that is considered the most haunted in Alabama. (The Haunting of Drish House) *** Drivers are reporting strange, ghostly orbs following them on dark roads. (Haunted Roads and Spook Lights) ==========SUDDEN DEATH OVERTIME: Dang Tan Ngoc is a well-known conman who has used the names of multiple dead soldiers to con veteran groups into giving him money. One identity he stole created a fascinating but dark story. (The Strange Return Of Master Sgt. John Hartley Robertson) *** A woman comes home to find her visiting sister murdered – and police were convinced she was the one who committed the crime. So what went wrong with the case to allow her to get away with it? (Did Ida Do It?) *** A bordello, pizza, and a haunting. You can find them all at the Red Onion Saloon. (Red Onion Saloon) *** Plus, I'll share two Creepypastas from Weirdo family members. “A Brief History of Egberting” from Louise Latham, and “Dreamality“ from Kara Raisch.==========SOURCES AND REFERENCES FROM TONIGHT'S SHOW:“The Lady Laughing In My Bedroom” by Geof James: https://tinyurl.com/yd4uddnx“New York Charnel House” posted at: https://tinyurl.com/ybsfs68x“The Beaux Arts Butterworth Building” by Meg van Huygen: https://tinyurl.com/y7h2mkyr“The Act of a Madman” by Robert Wilhelm: https://tinyurl.com/y9757b7d“A Malaysian Haunted House to Sell” by Brandon Grimes for Paranormality Magazine: http://weirddarkness.com/magazine“The Conjure Chest” for The Unexplained Mysteries: https://tinyurl.com/m9w2ffg“The Haunting of Drish House” by Amanda Penn for Horror Media: https://tinyurl.com/y8bovtwp“Haunted Roads and Spook Lights” by Brent Swancer for Mysterious Universe: https://tinyurl.com/ydfwg875“The Strange Return Of Master Sgt. John Hartley Robertson” by Derek Faraci for The 13th Floor: (site no longer exists)“Did Ida Do It?” by Robert Wilhelm for Murder By Gaslight: https://tinyurl.com/yamhvs69“The Red Onion Saloon” by Amanda Penn for Horror Media: https://tinyurl.com/y7te6wqe“A Brief History of Egberting” was written by Louise Latham for Weird Darkness“Dreamality” was written by Kara Raisch for Weird Darkness==========(Over time links seen above may become invalid, disappear, or have different content. I always make sure to give authors credit for material I use whenever possible. If I have overlooked doing so for a story, or if a credit is incorrect, please let me know and I will rectify it immediately. Some links may benefit me financially through qualifying purchases.)=========="I have come into the world as a light, so that no one who believes in me should stay in darkness." — John 12:46==========WeirdDarkness®, WeirdDarkness© 2024==========To become a Weird Darkness Radio Show affiliate, contact Radio America at affiliates@radioamerica.com, or call 800-807-4703 (press 2 or dial ext 250).
Get full-length pulp audiobooks, pulp eBooks, and old-time radio shows ABSOLUTELY FREE FOR IMMEDIATE DOWNLOAD by emailing WeirdDarkness@RadioArchives.com!TONIGHT'S RETRO RADIO SHOWS: Dimension X, “With Folded Hands” (April 15, 1950) *** The Eleventh Hour, “Accident On Curve” *** Escape, “The Vessel of Wrath” (May 10, 1953) *** Murder By Experts, “The Big Money” (July 25, 1949) *** Exploring Tomorrow, “Country Boy” (December 18, 1957) *** Five After The Hour, “The Man Without a Face” (February 23, 1945) *** Hall of Fantasy, “The Tell-Tale Heart” (June 01, 1953)TONIGHT'S WEIRD DARKNESS STORIES: More than a hundred years ago, reports described it as “the most weird and gruesome apartment in the world.” Why display an entire room full of grotesque items and open it to the public? (New York Charnel House) *** Kell's Irish Pub in Seattle has a creepy vibe to it, even if the displays and decorationsinside aren't meant to be. Perhaps that's because the building started its life as a massive mortuary. (The Beaux Arts Butterworth Building) *** Early one February morning in 1897, John Mars jumped out of bed from a sound sleep, and while the smell of breakfast cooking downstairs wafted up to the second level of the house, he inexplicably grabbed his pistol and went on a shooting spree of his own family. (The Act of a Mad Man) *** A four-year-old has a paranormal experience… and the man he grew into over 60 years later is still unsure of what happened to him. (The Lady Laughing In My Bedroom) *** A Malaysian Haunted House To Sell *** The brutal death of an African slave brings a curse upon the wooden chest he was ordered to construct. (The Conjure Chest) *** In Tuscaloosa, Alabama there is a home built by slaves that is considered the most haunted in Alabama. (The Haunting of Drish House) *** Drivers are reporting strange, ghostly orbs following them on dark roads. (Haunted Roads and Spook Lights) *** Dang Tan Ngoc is a well-known conman who has used the names of multiple dead soldiers to con veteran groups into giving him money. One identity he stole created a fascinating but dark story. (The Strange Return Of Master Sgt. John Hartley Robertson) *** A woman comes home to find her visiting sister murdered – and police were convinced she was the one who committed the crime. So what went wrong with the case to allow her to get away with it? (Did Ida Do It?) *** A bordello, pizza, and a haunting. You can find them all at the Red Onion Saloon. (Red Onion Saloon) *** Plus, I'll share two Creepypastas from Weirdo family members. “A Brief History of Egberting” from Louise Latham, and “Dreamality“ from Kara Raisch.SOURCES AND ESSENTIAL WEB LINKS…Get FREE radio shows, audiobooks, and more: WeirdDarkness@RadioArchives.comFind Old Time Radio Show to download: http://RadioArchives.com“The Lady Laughing In My Bedroom” by Geof James: https://tinyurl.com/yd4uddnx“New York Charnel House” posted at: https://tinyurl.com/ybsfs68x“The Beaux Arts Butterworth Building” by Meg van Huygen: https://tinyurl.com/y7h2mkyr“The Act of a Madman” by Robert Wilhelm: https://tinyurl.com/y9757b7d“A Malaysian Haunted House to Sell” by Brandon Grimes for Paranormality Magazine: http://weirddarkness.com/magazine“The Conjure Chest” for The Unexplained Mysteries: https://tinyurl.com/m9w2ffg“The Haunting of Drish House” by Amanda Penn for Horror Media: https://tinyurl.com/y8bovtwp“Haunted Roads and Spook Lights” by Brent Swancer for Mysterious Universe: https://tinyurl.com/ydfwg875“The Strange Return Of Master Sgt. John Hartley Robertson” by Derek Faraci for The 13th Floor: (site no longer exists)“Did Ida Do It?” by Robert Wilhelm for Murder By Gaslight: https://tinyurl.com/yamhvs69“The Red Onion Saloon” by Amanda Penn for Horror Media: https://tinyurl.com/y7te6wqe.= = = = = = = = = = = = = = = = = = = = = = = = = = = = = ="I have come into the world as a light, so that no one who believes in me should stay in darkness." — John 12:46Find out how to escape eternal darkness at https://weirddarkness.com/eternaldarknessWeirdDarkness® - is a registered trademark. Copyright, Weird Darkness, 2024.= = = = = = = = = = = = = = = = = = = = = = = = = = = = = =CUSTOM WEBPAGE: https://weirddarkness.com/WDRRM20240602
Te gast zijn journalist Maarten Huygen en leraar Erik Ex en we spreken over Maartens boek ‘Nog wat geleerd vandaag? Hoe kennis terugkeert in het onderwijs.' In het boek en ons gesprek beschrijft Maarten de lange geschiedenis van progressief onderwijs. Dit zgn. vernieuwingsonderwijs blijkt helemaal niet zo nieuw, want grijpt terug op onderwijsdenkers als Rousseau en Dewey. Progressief onderwijs heeft vaak de vorm van onderzoekend, levensecht leren en een kindgerichte pedagogiek. Het effect daarvan is echter dat het kennisniveau afneemt en de ongelijkheid toeneemt. Progressief onderwijs bevordert individuele kinderen met veel culturele bagage en boet in op gemeenschappelijkheid. Maarten pleit voor kennisgericht onderwijs, gestoeld op wetenschap en vakmanschap. Daar zou de politiek op moeten inzetten, zeker de progressieve partijen. Erik ziet het gemeenschappelijke als de essentie van onderwijs en noemt klassikaal onderwijs juist progressief en democratisch, omdat iedere leerling daarin als gelijk gezien wordt. Dit pleit volgens hem voor het centraal zetten van kennisoverdracht en van de leraar. Leerlingen hebben begeleiding nodig, omdat niet iedereen de benodigde kennis zelfstandig opdoet, een begeleiding die Rousseau volgens Maarten zelf ook gaf als privéleraar. Beiden pleiten ten slotte niet alleen voor kennisrijk onderwijs, maar ook voor een kennis- en instructierijke lerarenopleiding en een schoolleider die een collectieve professionele cultuur faciliteert en stimuleert van en voor ambachtelijke leraren. Deze podcast is mede mogelijk gemaakt door ATTC, schoolleidersopleiding in Hilversum, en De vallei van het goede leven.
Tickets for "The Bear" Pop up are almost sold out! Snag a ticket now at www.exploretock.com/dreamland Meg lists her 3 favorite North Korean restaurants in Dubai. Alex finds the right balance of pretentious. Copine makes a blueberry foil gras dish that makes Dave drink the blood of babies.
'Why It's So Bright at Night' is a periodic episode of Light Pollution News, where host Bill McGeeney sits down and chats to understand the positions of people who advocate for light. The show's intent is to spur conversation and understanding, helping all of us work together to a common unified goal of a better tomorrow for people, plants and animals. This episode, mentioned in the Feb 2024: A Space for Celebration episode, Jennifer Huygen started a petition in Stevenage, England to add lighting to a park. We explore why the lighting is needed, what types of lighting would be deemed acceptable, and seek to understand the cultural issues that are driving the need behind the lights.Support the showLike what we're doing? For the cost of coffee, you can become a Monthly Supporter? Your assistance will help cover server and production costs.
Ad Verbrugge in gesprek met publicist en voormalig redacteur hoger onderwijs bij het NRC Maarten Huygen, over zijn recente boek 'Nog wat geleerd vandaag? Hoe kennis terugkeert in het onderwijs'. Bronnen en links bij deze uitzending: Het boek van Maarten Huygen: https://www.boom.nl/auteur/110-22769_Huygen/100-15025_Nog-wat-geleerd-vandaag Een gesprek met onderwijsadviseur Marcel Schmeier: https://www.youtube.com/watch?v=t-7MIBkXbeU Meester Mark draait door: https://www.scriptum.nl/boeken/meester-mark-draait-door/
Rogier van Bemmel, Jelle van Baardewijk en Maarten van Huygen, schrijver van het boek 'Het nut van de man, de ins en outs van mannelijkheid' en voormalig NRC-journalist, gaan in deze editie van Nieuws van de Week uitvoerig in op de film 'Barbie' en bespreken ook de toekomst van het CDA en de stand van zaken in krantenland. Steun ons op petjeaf.com/denieuwewereld
This is a deep dive conversation on a topic that almost cost me my life. In 2013 I had a near death experience and a long road into recovery after contracting sepsis while in recovery from a burst appendix. I didn't realize how close to death I was until later. Dr Flavia Huygen's 30-year teaching, research and entrepreneurial career has been focused on molecular microbiology, with a particular focus on human pathogens and I want to share with you just how important this research is to our everyday life simply because it could save your life. She is the Founder, Executive Director and Chief Scientific Officer of Microbio, a new paradigm in pathogen detection and identificatio and a Doctor in Molecular Microbiology. Topics discussed: 1) The role of microbiology and how it can transform your life. 2) Can you rely on Captain Google for advice to save your life? 3) How we can navigate recovery from a near death experience tapping into the power of molecular microbiology expertise? 4) How the world of molecular microbiology has changed pre to post covid 5) :How AI can only improve how we navigate our health when matched with the right research 6) Flavia's next powerful step You can connect with Flavia and learn how she can help you navigate your life journey here Flavia and I met through the power of a partnership coffee date via NOva Entertainment. You can learn how you can build your own powerful, personal brand message and amplify your global network by signing up for our online Network Like a Pro Masterclass for $99.See omnystudio.com/listener for privacy information.
Help spread the darkness! VOTE FOR THIS EPISODE at https://weirddarkness.com/vote – you can vote up to 3X per day! Find Weird Darkness in your favorite podcast app at https://weirddarkness.com/listen. PLEASE SHARE WEIRD DARKNESS® in your social media and with others who loves paranormal stories, true crime, monsters, or unsolved mysteries like you do! Want to advertise in Weird Darkness? Visit https://weirddarkness.com/advertise for more info!IN THIS EPISODE: More than a hundred years ago, reports described it as “the most weird and gruesome apartment in the world.” Why display an entire room full of grotesque items and open it to the public? (New York Charnel House) *** Kell's Irish Pub in Seattle has a creepy vibe to it, even if the displays and decorations inside aren't meant to be. Perhaps that's because the building started its life as a massive mortuary. (The Beaux Arts Butterworth Building) *** Early one February morning in 1897, John Mars jumped out of bed from a sound sleep, and while the smell of breakfast cooking downstairs wafted up to the second level of the house, he inexplicably grabbed his pistol and went on a shooting spree of his own family. (The Act of a Mad Man) *** A four-year-old has a paranormal experience… and the man he grew into over 60 years later is still unsure of what happened to him. (The Lady Laughing In My Bedroom)SOURCES AND ESSENTIAL WEB LINKS…“The Lady Laughing In My Bedroom” by Geof James: https://tinyurl.com/yd4uddnx “New York Charnel House” posted at: https://tinyurl.com/ybsfs68x “The Beaux Arts Butterworth Building” by Meg van Huygen: https://tinyurl.com/y7h2mkyr “The Act of a Madman” by Robert Wilhelm: https://tinyurl.com/y9757b7d= = = = = = = = = = = = = = = = = = = = = = = = = = = = = =Weird Darkness theme by Alibi Music Library. Background music provided by Alibi Music Library, EpidemicSound and/or StoryBlocks with paid license. Music from Shadows Symphony (https://tinyurl.com/yyrv987t), Midnight Syndicate (http://amzn.to/2BYCoXZ) Kevin MacLeod (https://tinyurl.com/y2v7fgbu), Tony Longworth (https://tinyurl.com/y2nhnbt7), and Nicolas Gasparini (https://tinyurl.com/lnqpfs8) is used with permission of the artists.= = = = = = = = = = = = = = = = = = = = = = = = = = = = = =(Over time links seen above may become invalid, disappear, or have different content. I always make sure to give authors credit for the material I use whenever possible. If I somehow overlooked doing so for a story, or if a credit is incorrect, please let me know and I will rectify it in these show notes immediately. Some links included above may benefit me financially through qualifying purchases.)= = = = = = = = = = = = = = = = = = = = = = = = = = = = = ="I have come into the world as a light, so that no one who believes in me should stay in darkness." — John 12:46= = = = = = = = = = = = = = = = = = = = = = = = = = = = = =WeirdDarkness™ - is a production and trademark of Marlar House Productions. © 2023, Weird Darkness.= = = = = = = = = = = = = = = = = = = = = = = = = = = = = =TRANSCRIPT: https://weirddarkness.com/archives/15722This show is part of the Spreaker Prime Network, if you are interested in advertising on this podcast, contact us at https://www.spreaker.com/show/3655291/advertisement
Annelies Huygen geldt als een van de belangrijkste autoriteiten op het gebied van de warmtevoorziening in Nederland. Zij pleit voor een modernisering van de warmtenetten. En voor het terugdraaien van de privatisering. In Nederland is de warmtevoorziening van een klein aantal grote bedrijven, die als doel hebben winst maken en die veel te ver afstaan van de burger. Misschien is de huidige energiecrisis wel een uitgelezen moment om de noodzakelijke veranderingen in de wet door te voeren. In Denemarken heeft Huygen gezien dat het fundamenteel anders kan. Daar zijn de prijzen voor energie de laatste tijd zelfs nog gedaald.
Annelies Huygen geldt als een van de belangrijkste autoriteiten op het gebied van de warmtevoorziening in Nederland. Zij pleit voor een modernisering van de warmtenetten. En voor het terugdraaien van de privatisering. In Nederland is de warmtevoorziening van een klein aantal grote bedrijven, die als doel hebben winst maken en die veel te ver afstaan van de burger. Misschien is de huidige energiecrisis wel een uitgelezen moment om de noodzakelijke veranderingen in de wet door te voeren. In Denemarken heeft Huygen gezien dat het fundamenteel anders kan. Daar zijn de prijzen voor energie de laatste tijd zelfs nog gedaald.
This episode has been published and can be heard everywhere your podcast is available. #TataMariusz, czyli Mariusz Rzepka. Czytam dla dzieci, ale jeśli lubisz wiersze, bajki czy opowiadania - zostań ze mną, dla rodziców też się coś znajdzie. ;) A co? Np. wesołe wierszyki (często z przesłaniem), poważniejsze opowiadania i bajki edukacyjne, fragmenty książek, lektury i wiersze pisane przez najmłodszych. W każdym z nas siedzi dziecko. Odkryj je na nowo słuchając moich nagrań! ;) Zapraszam! https://tatamariusz.pl;
#TataMariusz, czyli Mariusz Rzepka. Czytam dla dzieci, ale jeśli lubisz wiersze, bajki czy opowiadania - zostań ze mną, dla rodziców też się coś znajdzie. ;) A co? Np. wesołe wierszyki (często z przesłaniem), poważniejsze opowiadania i bajki edukacyjne, fragmenty książek, lektury i wiersze pisane przez najmłodszych. W każdym z nas siedzi dziecko. Odkryj je na nowo słuchając moich nagrań! ;) Zapraszam! https://tatamariusz.pl;
#TataMariusz, czyli Mariusz Rzepka. Czytam dla dzieci, ale jeśli lubisz wiersze, bajki czy opowiadania - zostań ze mną, dla rodziców też się coś znajdzie. ;) A co? Np. wesołe wierszyki (często z przesłaniem), poważniejsze opowiadania i bajki edukacyjne, fragmenty książek, lektury i wiersze pisane przez najmłodszych. W każdym z nas siedzi dziecko. Odkryj je na nowo słuchając moich nagrań! ;) Zapraszam! https://tatamariusz.pl;
#TataMariusz, czyli Mariusz Rzepka. Czytam dla dzieci, ale jeśli lubisz wiersze, bajki czy opowiadania - zostań ze mną, dla rodziców też się coś znajdzie. ;) A co? Np. wesołe wierszyki (często z przesłaniem), poważniejsze opowiadania i bajki edukacyjne, fragmenty książek, lektury i wiersze pisane przez najmłodszych. W każdym z nas siedzi dziecko. Odkryj je na nowo słuchając moich nagrań! ;) Zapraszam! https://tatamariusz.pl;
Ad Verbrugge in gesprek met Annelies Huygen, hoogleraar ordening van energiemarkten aan de Universiteit Utrecht, over de energietransitie. Doe hier mee met de eindejaarsactie: https://www.gofundme.com/f/decemberactie-de-nieuwe-wereld-2021?utm_source=customer&utm_medium=copy_link&utm_campaign=p_cf+share-flow-1
#TataMariusz, czyli Mariusz Rzepka. Czytam dla dzieci, ale jeśli lubisz wiersze, bajki czy opowiadania - zostań ze mną, dla rodziców też się coś znajdzie. ;) A co? Np. wesołe wierszyki (często z przesłaniem), poważniejsze opowiadania i bajki edukacyjne, fragmenty książek, lektury i wiersze pisane przez najmłodszych. W każdym z nas siedzi dziecko. Odkryj je na nowo słuchając moich nagrań! ;) Zapraszam! https://tatamariusz.pl;
#TataMariusz, czyli Mariusz Rzepka. Czytam dla dzieci, ale jeśli lubisz wiersze, bajki czy opowiadania - zostań ze mną, dla rodziców też się coś znajdzie. ;) A co? Np. wesołe wierszyki (często z przesłaniem), poważniejsze opowiadania i bajki edukacyjne, fragmenty książek, lektury i wiersze pisane przez najmłodszych. W każdym z nas siedzi dziecko. Odkryj je na nowo słuchając moich nagrań! ;) Zapraszam! https://tatamariusz.pl;
#TataMariusz, czyli Mariusz Rzepka. Czytam dla dzieci, ale jeśli lubisz wiersze, bajki czy opowiadania - zostań ze mną, dla rodziców też się coś znajdzie. ;) A co? Np. wesołe wierszyki (często z przesłaniem), poważniejsze opowiadania i bajki edukacyjne, fragmenty książek, lektury i wiersze pisane przez najmłodszych. W każdym z nas siedzi dziecko. Odkryj je na nowo słuchając moich nagrań! ;) Zapraszam! https://tatamariusz.pl;
Like the podcast on Facebook – https://facebook.com/weirddarkness, follow on Twitter – https://twitter.com/weirddarkness, join the Weirdos Facebook Group – https://facebook.com/groups/marlarhouse, and sign up for the FREE email newsletter - https://weirddarkness.com/newsletter! Please SHARE Weird Darkness with someone who loves paranormal stories, true crime, monsters, or unsolved mysteries like you do! Recommending Weird Darkness to others helps make it possible for me to keep doing the show!IN THIS EPISODE: (Dark Archives episode from March 13, 2019) *** More than a hundred years ago, reports described it as “the most weird and gruesome apartment in the world.” Why display an entire room full of grotesque items and open it to the public? (New York Charnel House) *** Kell's Irish Pub in Seattle has a creepy vibe to it, even if the displays and decorations inside aren't meant to be. Perhaps that's because the building started its life as a massive mortuary. (The Beaux Arts Butterworth Building) *** Early one February morning in 1897, John Mars jumped out of bed from a sound sleep, and while the smell of breakfast cooking downstairs wafted up to the second level of the house, he inexplicably grabbed his pistol and went on a shooting spree of his own family. (The Act of a Mad Man) *** A four-year-old has a paranormal experience… and the man he grew into over 60 years later is still unsure of what happened to him. (The Lady Laughing In My Bedroom)SOURCES AND ESSENTIAL WEB LINKS…“The Lady Laughing In My Bedroom” by Geof James: https://tinyurl.com/yd4uddnx “New York Charnel House” posted at: https://tinyurl.com/ybsfs68x “The Beaux Arts Butterworth Building” by Meg van Huygen: https://tinyurl.com/y7h2mkyr “The Act of a Madman” by Robert Wilhelm: https://tinyurl.com/y9757b7d Weird Darkness theme by Alibi Music Library. Background music provided by Alibi Music, EpidemicSound and/or AudioBlocks with paid license. Music from Shadows Symphony (https://tinyurl.com/yyrv987t), Midnight Syndicate (http://amzn.to/2BYCoXZ), Kevin MacLeod (https://tinyurl.com/y2v7fgbu), Tony Longworth (https://tinyurl.com/y2nhnbt7), and/or Nicolas Gasparini/Myuu (https://tinyurl.com/lnqpfs8) is used with permission. = = = = = = = = = = = = = = = = = = = = = = = = = = = = = =(Over time links seen above may become invalid, disappear, or have different content. I always make sure to give authors credit for the material I use whenever possible. If I somehow overlooked doing so for a story, or if a credit is incorrect, please let me know and I will rectify it in these show notes immediately. Some links included above may benefit me financially through qualifying purchases.)= = = = = = = = = = = = = = = = = = = = = = = = = = = = = =WANT TO ADVERTISE ON WEIRD DARKNESS?Weird Darkness has partnered with AdvertiseCast to handle our advertising/sponsorship requests. They're great to work with and will help you advertise on the show. Email sales@advertisecast.com or start the process now at https://weirddarkness.com/advertise = = = = = = = = = = = = = = = = = = = = = = = = = = = = = ="I have come into the world as a light, so that no one who believes in me should stay in darkness." — John 12:46Find out how to escape eternal darkness at https://weirddarkness.com/eternaldarkness WeirdDarkness™ - is a production and trademark of Marlar House Productions. Copyright, 2021.= = = = = = = = = = = = = = = = = = = = = = = = = = = = = =00:25:07.541,
#TataMariusz, czyli Mariusz Rzepka. Czytam dla dzieci, ale jeśli lubisz wiersze, bajki czy opowiadania - zostań ze mną, dla rodziców też się coś znajdzie. ;) A co? Np. wesołe wierszyki (często z przesłaniem), poważniejsze opowiadania i bajki edukacyjne, fragmenty książek, lektury i wiersze pisane przez najmłodszych. W każdym z nas siedzi dziecko. Odkryj je na nowo słuchając moich nagrań! ;) Zapraszam! https://tatamariusz.pl;
#TataMariusz, czyli Mariusz Rzepka. Czytam dla dzieci, ale jeśli lubisz wiersze, bajki czy opowiadania - zostań ze mną, dla rodziców też się coś znajdzie. ;) A co? Np. wesołe wierszyki (często z przesłaniem), poważniejsze opowiadania i bajki edukacyjne, fragmenty książek, lektury i wiersze pisane przez najmłodszych. W każdym z nas siedzi dziecko. Odkryj je na nowo słuchając moich nagrań! ;) Zapraszam! https://tatamariusz.pl;
#TataMariusz, czyli Mariusz Rzepka. Czytam dla dzieci, ale jeśli lubisz wiersze, bajki czy opowiadania - zostań ze mną, dla rodziców też się coś znajdzie. ;) A co? Np. wesołe wierszyki (często z przesłaniem), poważniejsze opowiadania i bajki edukacyjne, fragmenty książek, lektury i wiersze pisane przez najmłodszych. W każdym z nas siedzi dziecko. Odkryj je na nowo słuchając moich nagrań! ;) Zapraszam! https://tatamariusz.pl;
From London: Esta semana el viaje de La Luz del Misterio, en London Radio World, en primer lugar hemos hablado de las declaraciones del expresidente Barack Obama, el pasado lunes, 17 de mayo, en programa de entretenimiento ‘The Late Show with James Corden’, en la cadena de televisión ‘CBS’, donde ha afirmado que militares de Estados Unidos han visto y filmado ovnis. Más tarde conectamos con Tailandia para comunicar con el gran compositor de música electrónica, Michel Huygen, con él conversaremos sobre su apasionante y larga trayectoria de más de 47 años dedicado a ayudar a despertar la conciencia a través de la música. Su amistad y colaboración con el Dr. Jiménez del Oso, en Busca del misterio, El Imperio del Sol y El Otro México. Recordaremos su colaboración con el compositor griego Vangelis que tuvo lugar en 1981 en su estudio, en la ciudad de Londres. Además de sus experiencias con otras realidades. Nuestro último tramo nos llevará a conocer cómo Cáceres se convertirá en la primera tierra sagrada budista del mundo no asiática. Existen cuatro lugares sagrados para el budismo en el mundo, todos ellos se encuentran en Asia. Pero ahora habrá un quinto: Cáceres. La ciudad extremeña ha iniciado el camino hacia la espiritualidad del amor y la compasión. Para ello, ejecutarán un proyecto de construcción de un gran complejo religioso. Tal condición situará a Cáceres y, en concreto, al entorno natural del Cerro de Arropez, en la quinta tierra sagrada budista del planeta, la primera fuera del continente asiático. Conectaremos con Extremadura para hablar de todo ello con José Manuel Vilanova, presidente de Lumbini Garden Foundation. Un viaje apasionante hacia la historia de ser humano que puedes conocer a través de La Luz del Misterio en London Radio World y sus plataformas.——————————————————— Más información sobre Michel Huygen: https://neuronium.com/ Más información sobre Cáceres, Quinta Tierra Santa: https://fundacionlumbinigarden.com/ Síguenos a través de: edenex.es ZTR Radio.online London Radio World En Ivoox Itunes Podomatic Más información: laluzdelmisterioradio.blogspot.com laluzdelmisterio@gmail.com
From London: Esta semana el viaje de La Luz del Misterio, en London Radio World, en primer lugar hemos hablado de las declaraciones del expresidente Barack Obama, el pasado lunes, 17 de mayo, en programa de entretenimiento ‘The Late Show with James Corden’, en la cadena de televisión ‘CBS’, donde ha afirmado que militares de Estados Unidos han visto y filmado ovnis. Más tarde conectamos con Tailandia para comunicar con el gran compositor de música electrónica, Michel Huygen, con él conversaremos sobre su apasionante y larga trayectoria de más de 47 años dedicado a ayudar a despertar la conciencia a través de la música. Su amistad y colaboración con el Dr. Jiménez del Oso, en Busca del misterio, El Imperio del Sol y El Otro México. Recordaremos su colaboración con el compositor griego Vangelis que tuvo lugar en 1981 en su estudio, en la ciudad de Londres. Además de sus experiencias con otras realidades. Nuestro último tramo nos llevará a conocer cómo Cáceres se convertirá en la primera tierra sagrada budista del mundo no asiática. Existen cuatro lugares sagrados para el budismo en el mundo, todos ellos se encuentran en Asia. Pero ahora habrá un quinto: Cáceres. La ciudad extremeña ha iniciado el camino hacia la espiritualidad del amor y la compasión. Para ello, ejecutarán un proyecto de construcción de un gran complejo religioso. Tal condición situará a Cáceres y, en concreto, al entorno natural del Cerro de Arropez, en la quinta tierra sagrada budista del planeta, la primera fuera del continente asiático. Conectaremos con Extremadura para hablar de todo ello con José Manuel Vilanova, presidente de Lumbini Garden Foundation. Un viaje apasionante hacia la historia de ser humano que puedes conocer a través de La Luz del Misterio en London Radio World y sus plataformas.——————————————————— Más información sobre Michel Huygen: https://neuronium.com/ Más información sobre Cáceres, Quinta Tierra Santa: https://fundacionlumbinigarden.com/ Síguenos a través de: edenex.es ZTR Radio.online London Radio World En Ivoox Itunes Podomatic Más información: laluzdelmisterioradio.blogspot.com laluzdelmisterio@gmail.com
'De man is uit de mode', stelt oud-journalist en schrijver Maarten Huygen in zijn onlangs verschenen boek Het nut van de man. Er is volgens hem veel oog voor de schadelijke kanten van mannelijkheid en voor hun oververtegenwoordiging in misdaad, seksueel misbruik en geweld. Maar staan daar ook voordelen tegenover, en wat zijn die dan? Aan de hand van muziek spreekt hij erover met Floortje Smit.
Toen publicist Maarten Huygen (jarenlang journalist en VS-correspondent voor NRC) iemand de titel van zijn nieuwe boek vertelde, Het Nut Van De Man, antwoordde die dat het waarschijnlijk een erg dun boek zou worden. In Oeverloos vertelt Huygen over mannelijkheid na #metoo en in tijden van nieuwe gedachten over gender. Wat blijken keer op keer mannelijke eigenschappen, waarin blinken mannen uit, waarin falen ze steeds opnieuw? En waarom? Huygen vertelt erover, en ondertussen bezingen artiesten de man: The Killers, Thin Lizzy, IDLES, Gorki. En natuurlijk Jeroen van Merwijk, met zijn klassieker 'Alle Mannen Moeten Dood'.
Toen publicist Maarten Huygen (jarenlang journalist en VS-correspondent voor NRC) iemand de titel van zijn nieuwe boek vertelde, Het Nut Van De Man, antwoordde die dat het waarschijnlijk een erg dun boek zou worden. In Oeverloos vertelt Huygen over mannelijkheid na #metoo en in tijden van nieuwe gedachten over gender. Wat blijken keer op keer mannelijke eigenschappen, waarin blinken mannen uit, waarin falen ze steeds opnieuw? En waarom? Huygen vertelt erover, en ondertussen bezingen artiesten de man: The Killers, Thin Lizzy, IDLES, Gorki. En natuurlijk Jeroen van Merwijk, met zijn klassieker 'Alle Mannen Moeten Dood'.
Ad Verbrugge in gesprek met voormalig NRC journalist en correspondent Maarten Huygen.
Join Drs. Jason Pope and Timothy Lubenow for a new episode of Abbott Virtual Scientific Forum Podcast In the Lupe: History of Radiofrequency. List to our esteemed faculty discuss the history and importance of utilizing Radiofrequency in your practice day to day. Cohen SP, Bhaskar A, Bhatia A, et al. Consensus practice guidelines on interventions for lumbar facet joint pain from a multispecialty, international working group. Reg Anesth Pain Med. 2020;45(6):424‐467. doi:10.1136/rapm-2019-101243Juch, J., Maas, E. T., Ostelo, R., Groeneweg, J. G., Kallewaard, J. W., Koes, B. W., Verhagen, A. P., van Dongen, J. M., Huygen, F., & van Tulder, M. W. (2017). Effect of Radiofrequency Denervation on Pain Intensity Among Patients With Chronic Low Back Pain: The Mint Randomized Clinical Trials. JAMA, 318(1), 68–81. https://doi.org/10.1001/jama.2017.7918Manchikanti L. et al. A systematic review and best evidence synthesis of effectiveness of therapeutic facet joint interventions in managing chronic spinal pain. Pain physician. 2015 Jul;18:E535-82. Rx OnlyBrief Summary: Prior to using these devices, please review the User’s Guide for a complete listing of indications, contraindications, warnings, precautions, potential adverse events, and directions for use. The system is intended to be used with leads and associated extensions that are compatible with the system.DRGIndications for Use: US: Spinal column stimulation via epidural and intra-spinal lead access to the dorsal root ganglion as an aid in the management of moderate to severe chronic intractable* pain of the lower limbs in adult patients with Complex Regional Pain Syndrome (CRPS) types I and II.***Study subjects from the ACCURATE clinical study had failed to achieve adequate pain relief from at least 2 prior pharmacologic treatments from at least 2 different drug classes and continued their pharmacologic therapy during the clinical study.**Please note that in 1994, a consensus group of pain medicine experts gathered by the International Association for the Study of Pain (IASP) reviewed diagnostic criteria and agreed to rename reflex sympathetic dystrophy (RSD) and causalgia, as complex regional pain syndrome (CRPS) types I and II, respectively. CRPS II (causalgia) is defined as a painful condition arising from damage to a nerve. Nerve damage may result from traumatic or surgical nerve injury. Changes secondary to neuropathic pain seen in CRPS I (RSD) may be present, but are not a diagnostic requirement for CRPS II (causalgia).International: Management of chronic intractable pain.Contraindications: US: Patients who are unable to operate the system, who are poor surgical risks. Patients who have failed to receive effective pain relief during trial stimulation.International: Patients who are unable to operate the system, are poor surgical risks, are pregnant, or under the age of 18.Warnings/Precautions: Diathermy therapy, implanted cardiac systems or other active implantable devices, magnetic resonance imaging (MRI), computed tomography (CT), electrosurgery devices, ultrasonic scanning equipment, therapeutic radiation, explosive and flammable gases, theft detectors and metal screening devices, lead movement, operation of machinery, equipment and vehicles, pediatric use, pregnancy, and case damage.Adverse Effects: Unpleasant sensations, changes in stimulation, stimulation in unwanted places, lead or implant migration, epidural hemorrhage, hematoma, infection, spinal cord compression, or paralysis from placement of a lead in the epidural space, cerebrospinal fluid leakage, tissue damage or nerve damage, paralysis, weakness, clumsiness, numbness, sensory loss, or pain below the level of the implant, pain where needle was inserted or at the electrode site or at IPG site, seroma at implant site, headache, allergic or rejection response, battery failure and/or leakage. Clinician’s Manual must be reviewed for detailed disclosure.SCSIndications for Use: Spinal cord stimulation as an aid in the management of chronic, intractable pain of the trunk and/or limbs, including unilateral or bilateral pain associated with the following: failed back surgery syndrome and intractable low back and leg pain.Contraindications: Patients who are unable to operate the system or who have failed to receive effective pain relief during trial stimulation.Warnings/Precautions: Diathermy therapy, implanted cardiac systems or other active implanted devices, magnetic resonance imaging (MRI), electrosurgery, explosive and flammable gases, theft detectors and metal screening devices, lead movement, operation of machinery, equipment and vehicles, pediatric use, pregnancy, and case damage. Patients who are poor surgical risks, with multiple illnesses, or with active general infections should not be implanted.Adverse Effects: Unpleasant sensations, changes in stimulation, stimulation in unwanted places, lead or implant migration, epidural hemorrhage, hematoma, infection, spinal cord compression, or paralysis from placement of a lead in the epidural space, cerebrospinal fluid leakage, paralysis, weakness, clumsiness, numbness, sensory loss, or pain below the level of the implant, pain at the electrode or IPG site, seroma at IPG site, allergic or rejection response, battery failure. Clinician’s Manual must be reviewed for detailed disclosure.RFAIndications for Use: The NT2000iXTM generator is intended for lesioning neural tissue. The NT2000iXTM generator is intended to be used for pain management. The NT2000iXTM generator is to be used only with separately cleared/approved lesion/temperature probes (NeuroTherm radiofrequency probes and SPINECATHTM and ACUTHERMTM catheters). The NT2000iXTM generator is indicated for use in the peripheral nervous system. Warnings/Precautions: Hazardous electrical output, electric shock hazard, explosion hazard, fire hazard, pooling hazard, ignition hazard, fuse replacement, risk of RF burns to patient, interference with active implants, interference with other equipment, probes. User’s Guide must be reviewed for detailed disclosure. Indications for Use: US: The IonicRF™ Generator, in combination with approved compatible electrodes and cannulae, is indicated as an aid in the management of pain in the nervous system. Examples include facet denervation, trigeminal rhizotomy, and related functional neurosurgical procedures.International: The IonicRF™ Generator, in combination with approved compatible electrodes and cannulae, is indicated as an aid in the management of pain in the nervous system. Examples include, but are not limited to, facet denervation, rhizotomy, and related functional neurosurgical procedures.Contraindications: The use of this device is contraindicated in patients with systemic infection or local infection in the area of the procedure.Warnings/Precautions: Hazardous electrical output, electric shock hazard, equipment failure, explosion hazard, fire hazard, pooling hazard, ignition hazard, risk of RF burns and unintended stimulation, risk of RF burns to patient, interference with active implants, redirection of high-frequency currents, interference with other equipment, shortwave or microwave equipment, apparent low output or failure of equipment, risk of patient injury, proper device use, non-sterile, accessories, continuity monitoring, inspection, mechanical damage, electrode positioning, use of fluids, dispersive connections, cleaning the generator, emergency stop.Adverse Effects: Damage to surrounding tissue through iatrogenic injury; nerve injury, including thermal injury, or puncture of the spinal cord or nerve roots, potentially resulting in radiculopathy, paresis, and paralysis; pain, pulmonary embolism, hemothorax or pneumothorax, infection, unintended puncture wound, including vascular puncture and dural tear, hemorrhage, and hematoma. User’s Guide must be reviewed for detailed disclosure.Simplicity™ III Disposable Radiofrequency ElectrodePRESCRIPTION AND SAFETY INFORMATIONRead this section to gather important prescription and safety information.INDICATION FOR USEThe Abbott Medical Simplicity™ III Disposable Radiofrequency Electrode is intended for use in the treatment of chronic pain by the ablation of neural tissue.DESCRIPTIONThe Simplicity III electrode is a disposable radiofrequency (RF) device consisting of three isolated electrodes along the shaft. Radiopaque markers are located between the distal and the middle electrodes, between the middle and the proximal electrodes, and below the proximal electrode. These radiopaque markers clearly show the separation of the three electrodes under X-ray. The Simplicity III electrode needs to be connected to an Abbott Medical RF generator using an Abbott Medical adapter cable.WARNINGSSharp; handle carefully.Do not proceed unless all electrodes read body temperature when connected and inserted into the patient.Stop if heat is felt at site of the grounding pad.When the Simplicity III electrode is used to perform lesion procedures in the sacral region, always ensure that the electrode does not enter any of the sacral foramen and that the electrode does not proceed inferior to the inferior border of the sacrum.Do not use the electrode if the package has been opened or damaged.Ensure the most proximal contact on the electrode is not too close to the dermis to prevent skin burn.Use of general anesthesia is not recommended during the procedure. It is advised to use local anesthesia or conscious sedation so patient interaction is possible.The electrode should only be used by physicians trained in the use of the device.The electrode is intended for single-use only. This device is not intended for bilateral use.The electrode should only be used with an Abbott Medical RF generator.During treatment with the Simplicity III electrode, the patient should continuously be monitored and evaluated for any unexpected symptoms.Before starting any thermal treatment with the electrode, ensure no motor nerves are in the vicinity of the electrode.Do not move the electrode while it is activated.Do not use the electrode if any damage is observed.Do not bend or reshape the electrode; this can cause permanent mechanical damage.Use minimal force and torque when manipulating the electrode; the handle has been designed to release if too much torque is applied.Reuse of single-use devices creates a potential risk of patient or user infections. Contamination of the device may lead to injury, illness, or death of the patient.Reprocessing may compromise the structural integrity of the device and/or lead to device failure.Cleaning, disinfection, and sterilization may compromise essential material and design characteristics, leading to device failure.AbbottOne St. Jude Medical Dr., St. Paul, MN 55117 USA, Tel: 1 651 756 2000Neuromodulation.Abbott™ Indicates a trademark of the Abbott group of companies.‡ Indicates a third party trademark, which is property of its respective owner.© 2020 Abbott. All Rights Reserved.MAT-2012132 v1.0| Item is approved for global use.
D Creations - Education, Science, Physics, Audio Books, Teach Learn, Story, Music, Songs, Literature
D Creations Talk Physics Series - Light Episode 3 Huygen's Wave Theory --- Send in a voice message: https://anchor.fm/d0531/message
Segundo día con otros tres temas del reciente "Torneremo ancora" de Franco Battiato: - Il vuoto - Povera patria - Come un camello in una grondaia Sigue Michel Huygen con otros tres temas de "Neo" disco grabado en Abbey Road Studios junto a la London Symphony Orchestra. - Imaginary Movement n⁰ 1, 2 y 3 Luego Lluis Capdevila, el tema "Breeding" que abre su cuarto disco "Ètim" grabado en Nueva York con producción propia y de la Cooperativa Falset Marçà del Priorato. Ayer pusimos un tema de Chema Saiz, de su disco "Solo album volumen 2". Hoy elegimos dos temas mas: Chema Saiz: Trinkle tinkel de Thelonious Monk, y Vals en Dm, del que es autor. Terminamos con - Fernando Lobo, de su disco "Versos robados", la canción "Viaje" con poema de Pilar Paz Pasamar - Dos: Alma de picea (Vals a once tiempos) del disco "Pulso impar" Dos son Esther Sánchez, violín y Pedro Bartolomé, guitarra y percusión. Escuchar audio
Card sharp, horse rider, telescope maker, and puts together some interesting clocks. It is a pity the writers of this article understand so little about Quantum Mechanics. MP4 recording MP3 recording Your browser does not support the audio element.
“THE LADY LAUGHING IN MY BEDROOM” and 3 More Terrifying True Stories! #WeirdDarknessIf you like the podcast, please leave a review in the podcast app you listen from, and share a link to the podcast on Facebook and Twitter to invite others to become Weirdos too!IN THIS EPISODE: (Dark Archives episode from March 13, 2019) *** More than a hundred years ago, reports described it as “the most weird and gruesome apartment in the world.” Why display an entire room full of grotesque items and open it to the public? (New York Charnel House) *** Kell’s Irish Pub in Seattle has a creepy vibe to it, even if the displays and decorations inside aren’t meant to be. Perhaps that’s because the building started its life as a massive mortuary. (The Beaux Arts Butterworth Building) *** Early one February morning in 1897, John Mars jumped out of bed from a sound sleep, and while the smell of breakfast cooking downstairs wafted up to the second level of the house, he inexplicably grabbed his pistol and went on a shooting spree of his own family. (The Act of a Mad Man) *** A four-year-old has a paranormal experience… and the man he grew into over 60 years later is still unsure of what happened to him. (The Lady Laughing In My Bedroom) TRANSCRIPT FOR THIS EPISODE…(Scroll to bottom of blog post): Sorry, there is no transcript for this archive episode.LINKS AND RESOURCES MENTIONED IN THE EPISODE…SUPPORT THE PODCAST…Become a patron: http://www.WeirdDarkness.com/WEIRDO Visit the store: http://www.WeirdDarkness.com/STORE Social media and contact info: http://www.WeirdDarkness.com/CONTACT STORY AND MUSIC CREDITS/SOURCES…(Note: Over time links can and may become invalid, disappear, or have different content.)“The Lady Laughing In My Bedroom” by Geof James: https://tinyurl.com/yd4uddnx “New York Charnel House” posted at: https://tinyurl.com/ybsfs68x “The Beaux Arts Butterworth Building” by Meg van Huygen: https://tinyurl.com/y7h2mkyr “The Act of a Madman” by Robert Wilhelm: https://tinyurl.com/y9757b7d Weird Darkness opening and closing theme by Alibi Music Library. Background music, varying by episode, provided by Alibi Music, EpidemicSound and/or AudioBlocks with paid license; Shadows Symphony (http://bit.ly/2W6N1xJ), Midnight Syndicate (http://amzn.to/2BYCoXZ), and/or Nicolas Gasparini/Myuu (https://www.youtube.com/user/myuuji) used with permission. MY RECORDING TOOLS… * MICROPHONE (Neumann TLM103): http://amzn.to/2if01CL * POP FILTER (AW-BM700): http://amzn.to/2zRIIyK * XLR CABLE (Mogami Gold Studio): http://amzn.to/2yZXJeD * MICROPHONE PRE-AMP (Icicle): http://amzn.to/2vLqLzg * SOFTWARE (Adobe Audition): http://amzn.to/2vLqI6E * HARDWARE (iMac Pro): https://amzn.to/2suZGkA I always make sure to give authors credit for the material I use. If I somehow overlooked doing that for a story, or if a credit is incorrect, please let me know and I’ll rectify it the show notes as quickly as possible. "I have come into the world as a light, so that no one who believes in me should stay in darkness." — John 12:46 Find out how to escape eternal darkness at https://www.youtube.com/watch?v=2IYmodFKDaMWeirdDarkness™ - is a registered trademark. Copyright ©Weird Darkness 2020.= = = = = = = = = = = = = = = = = = = = = = = = = = = = = =
Agradece a este podcast tantas horas de entretenimiento y disfruta de episodios exclusivos como éste. ¡Apóyale en iVoox! Programa emitido el 20 de octubre de 1997. Presentación de su disco "Psykya". Esta entrevista fue grabada telefónicamente y posteriormente editada para intercalar fragmentos de música. La grabación original fue registrada en soporte cassette y se pasó a mp3 mediante técnicas NO profesionales. La calidad de sonido no es todo lo buena que sería deseable, pero creemos que el valor documental de esta grabación suple estas deficiencias. A mitad de la reproducción existe un silencio que se corresponde con el cambio de cara de la cassette (qué tiempos aquellos).Escucha este episodio completo y accede a todo el contenido exclusivo de lostfrontier.org. Descubre antes que nadie los nuevos episodios, y participa en la comunidad exclusiva de oyentes en https://go.ivoox.com/sq/26825
Agradece a este podcast tantas horas de entretenimiento y disfruta de episodios exclusivos como éste. ¡Apóyale en iVoox! Programa emitido el 15 de abril de 1996. Esta entrevista fue emitida y grabada en directo. La grabación original fue registrada en soporte cassette y se pasó a mp3 mediante técnicas NO profesionales. La calidad de sonido no es todo lo buena que sería deseable, pero creemos que el valor documental de esta grabación suple estas deficiencias. A mitad de la reproducción existe un silencio que se corresponde con el cambio de cara de la cassette (qué tiempos aquellos).Escucha este episodio completo y accede a todo el contenido exclusivo de lostfrontier.org. Descubre antes que nadie los nuevos episodios, y participa en la comunidad exclusiva de oyentes en https://go.ivoox.com/sq/26825
Agradece a este podcast tantas horas de entretenimiento y disfruta de episodios exclusivos como éste. ¡Apóyale en iVoox! Programa emitido el 9 de octubre de 1995. Continuación de la entrevista iniciada en el programa anterior y que nos vimos obligados a dividir en 2 debido a su extensión, que excedía la duración de aquél programa (la radio manda). Esta entrevista fue grabada telefónicamente y posteriormente editada para intercalar fragmentos de música. La grabación original fue registrada en soporte cassette y se pasó a mp3 mediante técnicas NO profesionales. La calidad de sonido no es todo lo buena que sería deseable, pero creemos que el valor documental de esta grabación suple estas deficiencias. A mitad de la reproducción existe un silencio que se corresponde con el cambio de cara de la cassette (qué tiempos aquellos).Escucha este episodio completo y accede a todo el contenido exclusivo de lostfrontier.org. Descubre antes que nadie los nuevos episodios, y participa en la comunidad exclusiva de oyentes en https://go.ivoox.com/sq/26825
Agradece a este podcast tantas horas de entretenimiento y disfruta de episodios exclusivos como éste. ¡Apóyale en iVoox! Programa emitido el 9 de octubre de 1995. Primera parte de la entrevista mantenida con Michel Huygen que nos vimos obligados a dividir en 2 debido a su extensión, que excedía la duración de aquél programa (la radio manda). Esta entrevista fue grabada telefónicamente y posteriormente editada para intercalar fragmentos de música. La grabación original fue registrada en soporte cassette y se pasó a mp3 mediante técnicas NO profesionales. La calidad de sonido no es todo lo buena que sería deseable, pero creemos que el valor documental de esta grabación suple estas deficiencias. A mitad de la reproducción existe un silencio que se corresponde con el cambio de cara de la cassette (qué tiempos aquellos).Escucha este episodio completo y accede a todo el contenido exclusivo de lostfrontier.org. Descubre antes que nadie los nuevos episodios, y participa en la comunidad exclusiva de oyentes en https://go.ivoox.com/sq/26825
Maarten Huygen was redacteur hoger onderwijs bij het NRC. Hij schreef een essay over de mode om kinderen zelf te laten bepalen wat ze moeten leren. Ad Verbrugge en Huygen bespreken in dit interview waar dit vandaan komt en welke gevolgen het heeft. Is er ook een middenweg mogelijk? Het idee dat een kind het beste zichzelf kan onderwijzen, tegenovergesteld aan het traditionele idee dat je een kind moet beschaven, “stamt al uit de negentiende eeuw”, aldus Huygen. In verschillende landen is een dergelijke vorm van onderwijs ingevoerd. Zo bespreekt Huygen de gevolgen voor het onderwijs in Amerika, Frankrijk en andere Europese steden. Hoe is het in Nederland gesteld? De kennisbasis is ontzettend belangrijk. “Je hebt kennis nodig om creativiteit te kunnen ontplooien.” Ook leesproblemen komen voort uit een gebrek eraan. Wat zou het verschil in leerprestaties tussen Westerse en Aziatische studenten kunnen verklaren? Of het verschil tussen jongens en meisjes?
The black letter law and articles in this episode are: 2001 AUMF https://www.congress.gov/107/plaws/publ40/PLAW-107publ40.pdf 2002 AUMF https://www.congress.gov/107/plaws/publ243/PLAW-107publ243.pdf NATO Article 5 https://www.nato.int/cps/en/natohq/topics_110496.htm Text of Secretary Colin Powell’s speech to the UN in 2003 on Iraqi WMDs https://www.theguardian.com/world/2003/feb/05/iraq.usa Video of speech https://www.c-span.org/video/?c4716794/user-clip-colin-powells-speech U.S. Defense Department Law of War Manual https://dod.defense.gov/Portals/1/Documents/pubs/DoD%20Law%20of%20War%20Manual%20-%20June%202015%20Updated%20Dec%202016.pdf?ver=2016-12-13-172036-190 Senate Armed Forces Committee Hearing July 13, 2006 “Military Commissions in Light of the Supreme Court Decision in Hamdan V. Rumsfeld” Full Text https://www.govinfo.gov/content/pkg/CHRG-109shrg35144/pdf/CHRG-109shrg35144.pdf Senate Hearing Video https://www.c-span.org/video/?193392-1/military-commissions Hamdan v. Rumsfeld, 548 U. S. 557 (2006) https://www.supremecourt.gov/opinions/05pdf/05-184.pdf Geneva Conventions https://www.icrc.org/en/war-and-law/treaties-customary-law/geneva-conventions Uniform Code of Military Justice https://jsc.defense.gov/Portals/99/Documents/2019%20MCM%20(Final)%20(20190108).pdf?ver=2019-01-11-115724-610 Julie Huygen recently retired from the Air Force Court of Criminal Appeals after 21 years of service as an Air Force Judge Advocate General
The black letter law and articles in this episode are: U.S. Air Force JAG Corps https://www.airforce.com/careers/specialty-careers/jag/overview U.S. Army JAG Corps https://www.goarmy.com/jag.html U.S. Coast Guard JAG Corps https://www.uscg.mil/resources/legal/ U.S. Marine JAG Corps https://www.marines.com/becoming-a-marine/officer/marine-corps-law-program.html U.S. Navy JAG Corps https://www.jag.navy.mil/ “You Can’t Handle the Truth” https://www.youtube.com/watch?v=9FnO3igOkOk Julie Huygen recently retired from the Air Force Court of Criminal Appeals
Van de 1,5 miljoen woningen die het kabinet vóór 2030 van het aardgas wil halen, zal ongeveer de helft op een warmtenet worden aangesloten. Dat vraagt om een nieuw soort, innovatieve warmtenetten én een nieuwe marktordening, aldus mijn gast. Zij is principal consultant bij TNO en hoogleraar ‘regulering van de energiemarkten’ aan de Universiteit van Amsterdam. Over warmtenetten en hun rol in de energietransitie praat ik met Annelies Huygen.
Met het klimaatakkoord en energietransitie spreken de regeringspartijen duidelijk de wens uit te willen werken aan een duurzamere economie waarin fossiele brandstoffen een veel kleinere rol moeten gaan spelen. Tegelijkertijd is er kritiek. Over de kosten maar ook over de uitvoerbaarheid. Uit de uitslag van de afgelopen Provinciale Statenverkiezingen blijkt daarnaast wel dat de Nederlander er op dit moment nog weinig vertrouwen in heeft dat het zomaar goed komt met verduurzaming. Hoe komt dit precies en waar gaat het nog fout met het uitgestippelde beleid?
Sleepy Time Tales Podcast – Creating a restful mindset through relaxing bedtime stories
We join our brave young hero from Episode 001, Buddy, as his adventures get truly fantastical. Join me as I recount his adventure with a group of gnomes where SPOILER nothing really happens. Story: 15:39 Gnomes - The classic 70s work by Huygen and Poortviet: https://amzn.to/2I2WIcW Of how about some classic garden kitsch? Get yourself a gnome or two. https://amzn.to/2HQScyQ Website: Sleepy Time Tales Patreon: https://www.patreon.com/sleepytimetales Twitter: Sleepy Time Tales Podcast Facebook: Sleepy Time Tales Podcast YouTube: Sleepy Time Tales Music: http://loyaltyfreakmusic.com/ Music Patreon: https://tinyurl.com/loyaltyfreak Sources: http://mythology.wikia.com/wiki/Gnome https://www.britannica.com/art/gnome https://en.wikipedia.org/wiki/Gnome
“THE LADY LAUGHING IN MY BEDROOM” and 3 More Terrifying True Stories! #WeirdDarknessIN THIS EPISODE OF #WEIRDDARKNESS: More than a hundred years ago, reports described it as “the most weird and gruesome apartment in the world.” Why display an entire room full of grotesque items and open it to the public? (New York Charnel House) *** Kell’s Irish Pub in Seattle has a creepy vibe to it, even if the displays and decorations inside aren’t meant to be. Perhaps that’s because the building started its life as a massive mortuary. (The Beaux Arts Butterworth Building) *** Early one February morning in 1897, John Mars jumped out of bed from a sound sleep, and while the smell of breakfast cooking downstairs wafted up to the second level of the house, he inexplicably grabbed his pistol and went on a shooting spree of his own family. (The Act of a Mad Man) *** A four-year-old has a paranormal experience… and the man he grew into over 60 years later is still unsure of what happened to him. (The Lady Laughing In My Bedroom) SUPPORT THE PODCAST...Become a patron: http://www.patreon.com/marlarhouseCheck out all of the sponsors: http://www.WeirdDarkness.com/sponsorsAdvertise on Weird Darkness;: http://www.bgadgroup.com or call 770-874-3200Audiobooks narrated by Darren Marlar: http://www.WeirdDarkness.com/audiobooksWeird Darkness store (t-shirts, mugs, etc.): http://www.WeirdDarkness.com/storeWeird Darkness on Twitter: http://www.twitter.com/weirddarknessDarren Marlar on Twitter: http://www.twitter.com/darrenmarlarWeird Darkness Facebook page: http://www.Facebook.com/WeirdDarknessDarren Marlar Facebook page: http://www.Facebook.com/DarrenMarlar WEIRDOS OF MARLAR HOUSE Facebook Group: http://www.Facebook.com/groups/MarlarHouse STORY CREDITS AND/OR SOURCES…“The Lady Laughing In My Bedroom” by Geof James: https://www.myhauntedlifetoo.com/2018/12/17/the-lady-laughing-in-my-bedroom-1951-1952/“New York Charnel House” posted at: http://empiredelamort.com/2016/04/macabre-new-york-the-charnel-house-that-almost-was/“The Beaux Arts Butterworth Building” by Meg van Huygen: https://seattle.curbed.com/platform/amp/2018/10/31/18048486/pike-place-butterworth-haunted-history“The Act of a Madman” by Robert Wilhelm: http://www.murderbygaslight.com/2018/12/the-act-of-mad-man.htmlMusic provided by Midnight Syndicate http://amzn.to/2BYCoXZ and Shadow’s Symphony http://www.facebook.com/shadowssymphony/ - all music used with permission. All rights reserved. All other music provided by AudioBlocks.com with paid license. MY RECORDING TOOLS...* MICROPHONE (Neumann TLM103): http://amzn.to/2if01CL* POP FILTER (AW-BM700): http://amzn.to/2zRIIyK* XLR CABLE (Mogami Gold Studio): http://amzn.to/2yZXJeD* MICROPHONE PRE-AMP (Icicle): http://amzn.to/2vLqLzg* SOFTWARE (Adobe Audition): http://amzn.to/2vLqI6E* HARDWARE (MacBook Pro): http://amzn.to/2vQzD5g I always make sure to give authors credit for the material I use. If I somehow overlooked doing that for a story, or if a credit is incorrect, please let me know and I’ll rectify it the show notes as quickly as possible. Psalm 23:4 ESV = "Even though I walk through the valley of the shadow of death, I will fear no evil, for you are with me; your rod and your staff, they comfort me.” *** How to escape eternal death: https://www.youtube.com/watch?v=2IYmodFKDaM WeirdDarkness™ - © Marlar House Productions, 2019.
In de 17e aflevering zijn Maarten Huygen, Wytske Versteeg en Joost Steins Bisschop te gast, en geven ze antwoord op de vraag: ‘Waar verzet jij je tegen?’ Maarten Huygen is redacteur hoger onderwijs bij NRC Handelsblad, voormalig Chef Opinie en voormalig correspondent in de VS. Wytske Versteeg is auteur van Quarantaine, Boy, De wezenlozen en Dit is geen dakloze. Joost Steins Bisschop is partner bij Jungle Minds, voormalig vaste columnist voor Het Financieele Dagblad, publiceert op Frankwatching en is auteur van Chatten met je dochter, Wie weet of het waar is? en De online scorecard 3.0. Deze tweewekelijkse podcast is een spin-off van ‘Nederland in ideeën’. Een jaarlijks uitgegeven boek door Maven Publishing waarin 100 wetenschappers, ondernemers en kunstenaars jaarlijks één vraag beantwoorden, gesteld door een bekende vragensteller. Dit jaar stelde Anton Corbijn de vraag: ‘Waar verzet jij je tegen?’ In elke aflevering hoor je telkens 3 mensen zelf hun antwoord aan Anton Corbijn voorlezen. Het resultaat is een unieke verzameling prikkelende en originele antwoorden die de luisteraar intrigeert, verrijkt en inspireert. De Nederland in ideeën-podcast is onder redactie van wetenschappers Tim van Opijnen & Mark Geels en uitgever Sander Ruys - zij zullen elke twee weken de gasten introduceren en hun antwoorden bespreken. Intro tune: ‘I dunno’ van Grapes (ccmixter.org/files/grapes/16626_)
In this episode, we look at the work of four men who bridge the period between Galileo Galilei and Isaac Newton: Giovanni Battista Riccioli, Rene Descartes, Christiaan Huygens and Robert Hooke. In this discussion we pay particular attention to each man's work in physics that will set the stage for Newton's great synthesis.
SPOILER ALERT! We will ruin these movies for you (Movies listed Below) Alex has John back on the podcast so they can talk about their favorite Space-Related Movies and other things that happen to pop-up during the episode. Alex also opens with what happened Today in Space: The ISS alarm about a possible leak that occurred @ 4AM EST this morning and what we know What the ESA's Huygens Probe has accomplished and what we know about Titan because of it Enjoy! EXPLICIT MATERIAL Possible Spoiler: Movies that will be ruined for you (Not in order) Total Recall Armageddon Chronicles of Riddick Interstellar Star Trek Aliens Apollo 13 SPACEBALLS NO Star Wars Serenity Gravity Wrath of Kahn Europa Report Alien The Fifth Element Galaxy Quest E.T. Elysium Space Links: http://www.universetoday.com/118175/ammonia-leak-on-the-iss-forces-evacuation-of-us-side-crew-safe/ Links to tweets I refer to in this podcast: @NASA https://twitter.com/NASA/status/555353675418599424 @fcain https://twitter.com/fcain/status/555379135103520768 @AstroSamantha https://twitter.com/AstroSamantha/status/555381253961433088 @csa_asc https://twitter.com/csa_asc/status/555393101465133057 The ESA's Huygens Probe & Titan Accomplishments http://www.esa.int/Our_Activities/Space_Science/Highlights/Ten_years_at_Titan Titan by the numbers Credits: NASA/JPL-Caltech
Mundos Lejanos. Concierto de Michel Huygen, en el VII Congreso Vida después de la Vida, que tuvo lugar los días 25 y 26 de octubre de 2014 en Albacete (España) ___________________________________ Michel es un referente mundial de la música electrónica. Fundador del grupo Neuronium, en 1990 editó el disco OLIM, una música que mucho de nosotros recordamos en los documentales del Dr. Jiménez del Oso. Además Michel forma parte del grupo de amigos que le rendimos homenaje en este congreso. Por todo ello, este concierto es parte del homenaje a Fernando donde, escuchando la música de Michel Huygen, nos trasladaremos con el pensamiento a las pirámides de Egipto, las líneas de Nazca, y otros muchos lugares mágicos de nuestro planeta. MICHEL HUYGEN - NEURONIUM MICHEL HUYGEN, sintesista, crea NEURONlUM en 1976. Graba en 1977 para el sello inglés HARVEST de EMI, el primer álbum de NEURONIUM titulado QUASAR 2C361, también siendo el primer disco de música cósmica jamás grabado en España . Forman también entonces parte de Neuronium , Carlos Guirao y Albert Giménez . El 7 de Mayo de 1978, NEURONIUM participa en el Festival de Ciencia Ficción de Metz (Francia) , representando a España. En Marzo de 1981, el grupo viaja por primera vez a Londres, invitado por VANGELlS, para interpretar juntos música compuesta por Michel Huygen, para un show de televisión, filmado por Televisión Española para su programa MUSICAL EXPRESS. EL resultado es realmente asombroso y la simbiosis es total entre los dos estilos y sonidos . Después del lanzamiento de CHROMIUM ECHOES, el quinto álbum de NEURONIUM, Carlos Guirao deja el grupo y por lo tanto NEURONIUM sigue capitaneado exclusivamente por Michel Huygen, su creador. Michel lanza al mercado y al mismo tiempo que el quinto álbum de NEURONIUM, su primer álbum sólo titulado ABSENCE OF REALlTY, un disco muy relajante e intimista.. En Mayo de 1986, Michel es encargado de ser el responsable del departamento de música electrónica del Centro de Arte Reina Sofía de Madrid, inaugurado por su Majestad la Reina ese mismo mes. En 1988, se están filmando nuevas series de documentales sobre antiguas civilizaciones desaparecidas, en Perú y México. Michel compone la banda sonora completa de los 26 capítulos de media hora cada uno. Entre Octubre de 1989 y Abril de 1990, Michel compone, graba y mezcla su nuevo álbum solo INTlMO, el más profundo, intimista y revelador de todos. Es el complemento especial y emocional de NUMERlCA. En ese período, Michel recibe el encargo para la banda sonora de una nueva serie de FERNANDO JIMENEZ DEL OSO, y JUAN JOSÉ BENITEZ titulada EN BUSCA DEL MISTERIO. En Diciembre de 1995 (en todo el mundo) y Junio de 1996 (España) verá el lanzamiento de ASTRALlA: una invitación al viaje astral con billete de retorno, a través de una suite de 67 minutos...¿ Preparados para el viaje? Será el álbum numero 24 compuesto por Michel Huygen, totalmente cósmico, con la colaboración del Dr. Fernando Jiménez Del Oso... El 1 de Julio de 1995, España pasa a presidir El Consejo de la Unión Europea, y Michel Huygen recibe el encargo de componer el tema musical que sirve de estandarte a un CD ROM titulado "e " España 1995. Michel titula este tema "ESPAÑA EN CLAVE FUTURA". El año 2000 verá la luz de DIRECTO AL CORAZÓN ,el álbum nominado en España por los V premios de la Música ,como mejor álbum del año en todas las categorías (Pop,rock,jaz...),junto a Alejandro Sanz y la Oreja de Van Gogh.. Este álbum,el 28º de la discografía de Michel Huygen , es un álbum de pura música romántica cibernética. El año 2002 ve la creación del sello NEURONIUM RECORDS como sello personal de Michel Huygen y distribuido en todo el mundo por BLANCO y NEGRO Music de Barcelona. La grabación del concierto de Neuronium acaba de ver la luz en Marzo de 2014 bajo el título de NOCNY LOT (VUELO NOCTURNO, en polaco) . En total, y hasta el día de hoy la discografía de Neuronium supera ya los 40 discos editados. http://www.michelhuygen.com/ ------------------------------------------------------------------------------- http://www.vidadespuesdelavida.es http://www.mindalia.com - La Red Social de Ayuda a través del Pensamiento http://www.mindaliaradio.com - La Radio del Pensamiento Positivo http://www.circulosdeayuda.com Los vídeos de esta y otras conferencias y entrevistas de interés en http://www.mindaliatelevision.com Puedes escuchar este y otros audios en http://mindaliacomradio.ivoox.com
Mundos Lejanos. Concierto de Michel Huygen, en el VII Congreso Vida después de la Vida, que tuvo lugar los días 25 y 26 de octubre de 2014 en Albacete (España) ___________________________________ Michel es un referente mundial de la música electrónica. Fundador del grupo Neuronium, en 1990 editó el disco OLIM, una música que mucho de nosotros recordamos en los documentales del Dr. Jiménez del Oso. Además Michel forma parte del grupo de amigos que le rendimos homenaje en este congreso. Por todo ello, este concierto es parte del homenaje a Fernando donde, escuchando la música de Michel Huygen, nos trasladaremos con el pensamiento a las pirámides de Egipto, las líneas de Nazca, y otros muchos lugares mágicos de nuestro planeta. MICHEL HUYGEN - NEURONIUM MICHEL HUYGEN, sintesista, crea NEURONlUM en 1976. Graba en 1977 para el sello inglés HARVEST de EMI, el primer álbum de NEURONIUM titulado QUASAR 2C361, también siendo el primer disco de música cósmica jamás grabado en España . Forman también entonces parte de Neuronium , Carlos Guirao y Albert Giménez . El 7 de Mayo de 1978, NEURONIUM participa en el Festival de Ciencia Ficción de Metz (Francia) , representando a España. En Marzo de 1981, el grupo viaja por primera vez a Londres, invitado por VANGELlS, para interpretar juntos música compuesta por Michel Huygen, para un show de televisión, filmado por Televisión Española para su programa MUSICAL EXPRESS. EL resultado es realmente asombroso y la simbiosis es total entre los dos estilos y sonidos . Después del lanzamiento de CHROMIUM ECHOES, el quinto álbum de NEURONIUM, Carlos Guirao deja el grupo y por lo tanto NEURONIUM sigue capitaneado exclusivamente por Michel Huygen, su creador. Michel lanza al mercado y al mismo tiempo que el quinto álbum de NEURONIUM, su primer álbum sólo titulado ABSENCE OF REALlTY, un disco muy relajante e intimista.. En Mayo de 1986, Michel es encargado de ser el responsable del departamento de música electrónica del Centro de Arte Reina Sofía de Madrid, inaugurado por su Majestad la Reina ese mismo mes. En 1988, se están filmando nuevas series de documentales sobre antiguas civilizaciones desaparecidas, en Perú y México. Michel compone la banda sonora completa de los 26 capítulos de media hora cada uno. Entre Octubre de 1989 y Abril de 1990, Michel compone, graba y mezcla su nuevo álbum solo INTlMO, el más profundo, intimista y revelador de todos. Es el complemento especial y emocional de NUMERlCA. En ese período, Michel recibe el encargo para la banda sonora de una nueva serie de FERNANDO JIMENEZ DEL OSO, y JUAN JOSÉ BENITEZ titulada EN BUSCA DEL MISTERIO. En Diciembre de 1995 (en todo el mundo) y Junio de 1996 (España) verá el lanzamiento de ASTRALlA: una invitación al viaje astral con billete de retorno, a través de una suite de 67 minutos...¿ Preparados para el viaje? Será el álbum numero 24 compuesto por Michel Huygen, totalmente cósmico, con la colaboración del Dr. Fernando Jiménez Del Oso... El 1 de Julio de 1995, España pasa a presidir El Consejo de la Unión Europea, y Michel Huygen recibe el encargo de componer el tema musical que sirve de estandarte a un CD ROM titulado "e " España 1995. Michel titula este tema "ESPAÑA EN CLAVE FUTURA". El año 2000 verá la luz de DIRECTO AL CORAZÓN ,el álbum nominado en España por los V premios de la Música ,como mejor álbum del año en todas las categorías (Pop,rock,jaz...),junto a Alejandro Sanz y la Oreja de Van Gogh.. Este álbum,el 28º de la discografía de Michel Huygen , es un álbum de pura música romántica cibernética. El año 2002 ve la creación del sello NEURONIUM RECORDS como sello personal de Michel Huygen y distribuido en todo el mundo por BLANCO y NEGRO Music de Barcelona. La grabación del concierto de Neuronium acaba de ver la luz en Marzo de 2014 bajo el título de NOCNY LOT (VUELO NOCTURNO, en polaco) . En total, y hasta el día de hoy la discografía de Neuronium supera ya los 40 discos editados. http://www.michelhuygen.com/ ------------------------------------------------------------------------------- http://www.vidadespuesdelavida.es http://www.mindalia.com - La Red Social de Ayuda a través del Pensamiento http://www.mindaliaradio.com - La Radio del Pensamiento Positivo http://www.circulosdeayuda.com Los vídeos de esta y otras conferencias y entrevistas de interés en http://www.mindaliatelevision.com Puedes escuchar este y otros audios en http://mindaliacomradio.ivoox.com
Zur Zeit arbeitet die gelernte Tischlerin auf einer Baustelle in Süddeutschland, davor war sie fünf Jahre auf der Walz, wie die Wanderschaft der Handwerksgesellen heißt. Jetzt will sie sich als Kabarettistin einen Namen machen. Auf der Bühne spielt sie mit den Klischees von Frauen im Handwerk. Nächste Woche tritt sie in ihrer Heimat Bonn auf (13.7., Kult 41).
Huygen’s wave theory, Newton’s corpuscular theory, Young’s double slit experiment, Double slit interference, Diffraction, Single slit interference, The electromagnetic nature of light, The electromagnetic spectrum, Light as electromagnetic radiation
We have considered thus far the diffraction of fields according to Huygen’s principle. We decompose the field at each plane into a superposition of spherical waves, and then we can propagate the fields by allowing those spherical waves to expand. The next step is to consider what happens when we introduce a lens into the optical path. Our treatment of the lens will follow the treatment of Goodman. At every point in the lens we consider the thickness of the lens, and treat the lens as something that introduces a phase delay in the fields that pass through that point.
We look at Fraunhofer diffraction from a slit and for a Gaussian beam. We use Huygen's principle and also discuss Babinet's principle
We Introduce Huygen's principle and Fermat's principle and use them to derive Snell's law and the law of reflection.
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