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Summary In this episode of the Future of Dermatology podcast, Dr. Faranak Kamangar interviews Dr. Natasha Atanaskova Mesinkovska MD PhD, a renowned dermatologist and researcher. They discuss Dr. Mesinkovska's journey in dermatology, her passion for hair research, the challenges of aging in dermatology, and the implications of chemical sunscreens on hair health. The conversation highlights the evolving landscape of dermatology, the importance of patient care, and the need for continued education in the field. In this conversation, the speakers delve into the evolving landscape of scalp care and its intersection with skincare trends, discussing the importance of scalp health and the various treatments available, including PRP and minoxidil. They also engage in a rapid-fire segment addressing treatment approaches for alopecia areata in different age groups, emphasizing the significance of addressing comorbidities and the potential of new treatments like JAK inhibitors. The discussion concludes with an exploration of exciting innovations in dermatology, including advancements in non-invasive imaging and AI technologies. Takeaways Dr. Mesinkovska emphasizes the importance of mentorship in medicine. The podcast aims to create a positive environment for dermatology professionals. Aging affects not just skin but also hair health. Chemical sunscreens may have adverse effects on hair conditions. The landscape of hair research is evolving with new treatment options. Dermatology interfaces with patients' psychological perceptions of aging. The importance of understanding the social aspects of dermatological conditions. Dr. Mesinkovska's journey reflects the American dream in medicine. The role of AI in enhancing dermatological practices is promising. Frontal fibrosing alopecia is a growing concern in dermatology. Scalp care is increasingly recognized as part of skincare. PRP treatments are popular for scalp rejuvenation. Regular hair washing is essential for scalp health. Preservatives in products serve important functions. Oils and ceramides are crucial for scalp hydration. Anti-dandruff shampoos can help maintain scalp balance. Atopy is a significant factor in alopecia in children. Minoxidil can help maintain hair density. New technologies in dermatology are promising. The future of dermatology is bright with innovative treatments. Chapters 00:00 - Introduction to the Future of Dermatology Podcast 02:06 - Meet Dr. Natasha Mesinkovska: A Dermatology Pioneer 05:15 - The Journey of a Dermatologist: Passion and Purpose 09:14 - The Evolving Landscape of Hair Research 12:36 - Aging and Its Impact on Dermatology 14:08 - Chemical Sunscreens and Their Effects on Hair Health 16:56 - Navigating Scalp Care and Skincare Trends 21:23 - Rapid Fire on Alopecia Areata Treatment 29:24 - Exciting Innovations in Dermatology
Join Dr. Renda Knapp, a board-certified OB/GYN, and Dr. Rachel Schultz, a pediatric specialist, as they tackle one of the most common skin conditions affecting infants: eczema (atopic dermatitis). In this informative podcast, our medical experts explain everything parents need to know about managing their baby's sensitive skin. This podcast offers practical guidance for daily management and long-term care. Whether you're a new parent noticing your baby's first patches of dry, irritated skin or looking for better ways to manage your child's established eczema, this podcast delivers compassionate, evidence-based advice to help your little one find relief. Subscribe for weekly episodes.
In this month's episode we welcome back Dr Matthew Muir to talk about PEA and its application in small animal practice. Topics discussed include: What is palmitoylethanolamide (PEA)? Mechanism of actions of PEA. Bioavailability of PEA - which form should we use and why? PEA has been available since the 1950's, why hasn't it been used more in veterinary medicine? CBD vs PEA, how are they similar and how do they differ? When to recommend PEA over CBD. Dr Muir discusses the safety profile of palmitoylethanolamide. Atopy and PEA - should PEA be used long term or short term? Evidence for use of PEA in animals and humans. How Dr Muir uses PEA in his practice? Matt shares some personal experience of ideal doses for certain conditions. See omnystudio.com/listener for privacy information.
Atopic conditions and environmental factors with Dr. Ian Myles - Risk factors for atopy - Second intention? More like second INFECTION! Want to donate to the cause? Do so here! http://www.uofuhealth.org/dermasphere - Check out our video content on YouTube: https://www.youtube.com/@dermaspherepodcast and VuMedi!: https://www.vumedi.com/channel/dermasphere/ The University of Utah's Dermatology ECHO: https://physicians.utah.edu/echo/dermatology-primarycare - Connect with us! - Web: https://dermaspherepodcast.com/ - Twitter: @DermaspherePC - Instagram: dermaspherepodcast - Facebook: https://www.facebook.com/DermaspherePodcast/ - Check out Luke and Michelle's other podcast, SkinCast! https://healthcare.utah.edu/dermatology/skincast/ Luke and Michelle report no significant conflicts of interest... BUT check out our friends at: - Kikoxp.com (a social platform for doctors to share knowledge) - https://www.levelex.com/games/top-derm (A free dermatology game to learn more dermatology!)
The fascinating history of dog food. The danger of modern, ultra-processed dog food. How to reduce your dog's chance of getting cancer. A survey of 12,000 dogs shows how diet affects their health. Atopy in dogs. More on the scientifically proven benefits of a raw diet thanks to research carried out by the University of Helsinki.This series was made with the financial support of the artisan, raw dog food producers Honey's Real Dog Food. Thanks to Pod People Productions.
According to pet insurance companies, the number one reason for bringing your dog to the veterinary hospital is because of allergies!! August is Itchy Pet Awareness Month! More than 30 million households in the United States have a pet who suffers from pruritus, which is the medical term for “itchy”. Reasons for this itchiness includes external parasites, like fleas, food allergies, and a condition known as ATOPY, or allergies to various things in the environment. From Noah's Animal Hospitals and our Investigative Reporter for Pet Pals TV Tom Dock has more.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Welcome to another episode of the Empowered Nutrition podcast! We are so thrilled to have you here. As we bask in the warmth of summer, we're bringing you a series of quick and casual episodes to match those chill summer vibes. So, if you're listening to this as it comes out, get ready for a dose of valuable knowledge while you soak up the sun! Before we dive into today's topic, I want to take a moment to express our heartfelt gratitude. We don't usually ask for it, but your support means the world to us. If you love this podcast as much as we love creating it, please consider leaving a positive review wherever you listen to podcasts. Your feedback helps us spread the message of empowerment and good health to even more listeners! Now, let's unveil the mystery behind a pressing concern: allergies and their unexpected link to gut health. Yes, you heard that right! Allergies are becoming increasingly common, affecting around 10% of adults. But why is this happening, and what can we do about it? Stay tuned as we explore the fascinating world of epidemiology and its connection to your gut health. Prepare to be amazed at the intricate dance between your microbiome and those pesky allergies! So, whether you're lounging at the beach or taking a leisurely stroll, grab your earbuds, and let's embark on this eye-opening journey together! Are you ready to discover the hidden connection between allergies and gut health? Let's dive in!
Immune explains how mast cells, IgE antibody, and the brain collaborate to promote avoidance of certain foods to evade allergic responses. Hosts: Vincent Racaniello, Cynthia Leifer, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts. RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Mast cells and immune avoidance behavior (Nature) Immune sensing of food allergens promotes avoidance (Nature) Immunology that underlies picky eating (Nature) Time stamps by Jolene. Thanks! Music by Steve Neal. Immune logo image by Blausen Medical Send your immunology questions and comments to immune@microbe.tv
VetFolio - Veterinary Practice Management and Continuing Education Podcasts
There's an alphabet soup of medications and therapies available for dogs and cats suffering with atopic dermatitis, so how do you know what therapeutic course to follow to ensure a successful outcome for your itchy canine and feline patients? In this episode of VetFolio Voice, host Dr. Cassi chats with Dr. Kacie Blessing, a veterinary dermatologist, about using every tool in your veterinary toolbox to give your patients relief from this frustrating and challenging condition. Earn CE while learning about blood and skin allergy testing, immunotherapy options, diets for canine atopic dermatitis, topical therapies for dogs, medication options, and how cats present with atopic dermatitis. Want to earn CE from this podcast? Be sure to log into VetFolio and take the quiz to qualify for your CE credit! https://www.vetfolio.com/courses/utilizing-all-the-tools-in-your-caninefeline-atopy-toolbox-podcast-quiz
Don't be rash! Tune in to this discussion on how to TREAT gut conditions caused by food and environmental sensitivities or allergens. Dr. Kapadia recaps testing and dives into her favorite pharmaceutical and natural interventions to curb these pesky symptoms. Topics covered: - Blood testing for food and airborne allergies - Debate on food sensitivities vs intestinal permeability - Home/lifestyle changes to reduce the effects of environmental allergens - Drug options for improving symptoms and lessening reactivity - Do plant-based products work? - ...And a brief tinea tangent #allergies #sensitivities #foodsensitivities #inhalants #IgGFoodtesting #IgEbloodtesting #cromolyn #ketotifen #H1blockers #H2blockers #quercitin #toenailfungus #eliminationdiet Dr. Ami Kapadia, MD, ABFM, ABIHM: https://www.amikapadia.com/ Dr. Rebecca Sand, ND, LAc: https://www.drrebeccasand.com/ Dr. Ilana Gurevich, ND, LAc: https://www.naturopathicgastro.com/
This week we cover an increasingly common diagnosis - eosinophilic esophagitis. We will discuss the clinical presentation, diagnostic criteria, and help you remember the approach to treatment. Written by: Dr. Michael Scaffidi (Internal Medicine Resident)Reviewed by: Dr. Samir Grover (Gastroenterologist) and Dr. Don Thiwanka Wijeratne (General Internist)Support the show
So... you have ruled out flea and food allergy and now it is time for THE talk. The chronic, lifelong, multimodal therapy required atopic dermatitis talk? For such a common disease, how come this spiel can be so difficult? Check out this week's episode of The Derm Vet podcast for tips and tricks!
In this VETgirl online veterinary continuing education podcast, we interview Dr. Alice Jeromin, DACVD on atopy in cats, which has since been renamed Feline Atopic Skin Syndrome (FASS). Are you missing the diagnosis of atopy in cats? Find out what the clinical signs of atopy are in cats, what signalment, age and breed gets it, and most importantly, how to treat Feline Atopic Skin Syndrome in your feline patients!
Diagnosis of canine atopic dermatitis... it can be time consuming to do all the rule outs (though necessary). But there is criteria that can make it very likely (or unlikely) that you are dealing with canine atopic dermatitis. Check out this week's episode of the podcast for the hints!
In this episode, Marshall Animal Clinic mixed animal veterinarian, Dr Tracey Westegaard gives 5 recommendations to help your dog be more comfortable through the allergy season. She will give you actionable steps you can t start immediately...and that does NOT include giving Benadryl. Sorry we are a little late to game publishing this in October.
Managing canine atopic dermatitis long-term can be difficult and frustrating. Between managing flares and client education there can be a lot to juggle. Today's podcast welcomes Fiona Bateman, BVSc, MANZCVS, DACVD. She is a senior veterinary dermatologist for Zoetis.We discuss how to work with clients to manage these chronic cases, long-term anti-pruritic therapy and identifying flare factors. Though these cases can be confusing and hard to manage, there are some key tips that can help navigate this common case presentation.This podcast is sponsored by Zoetis.
I opened it up on Instagram! In this episode, I answer the top questions submitted regarding canine atopic dermatitis. This is a great summary of some of the most important aspects of this chronic, frustrating disease.
Welcome Valerie Fadok, DVM, PhD, DACVD to the podcast to discuss canine allergic and atopic dermatitis! She is a senior veterinary dermatologist with Zoetis.We've come a long way in our ability to manage allergic skin diseases in dogs. Due to our increased knowledge based on research, there are better therapeutics available. We have learned that several Type 2 cytokines such as IL-2, IL-4, IL-6, IL-13, and IL-31 are major players in mediating allergic pruritus and inflammation. These cytokines mediate their action through Janus kinase-1 and appear early in the allergic inflammation cascade. It is so important with the management of allergic and atopic dogs that we continue to have studies showing the effect of therapies on itch and inflammation. Check out this episode of the podcast to learn more!This podcast was sponsored by Zoetis. Zoetis is dedicated to changing the way we approach canine pruritus to protect the bonds between the pet, the owner and the veterinary team. Visit ScienceofStrongerBonds.com for more information.APOQUEL-IMPORTANT SAFETY INFORMATIONDo not use Apoquel in dogs less than 12 months of age or those with serious infections. Apoquel may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse. Consider the risks and benefits of treatment in dogs with a history of recurrence of these conditions. New neoplastic conditions (benign and malignant) were observed in clinical studies and post-approval. Apoquel has not been tested in dogs receiving some medications including some commonly used to treat skin conditions such as corticosteroids and cyclosporines. Do not use in breeding, pregnant, or lactating dogs. Most common side effects are vomiting and diarrhea. Apoquel has been used safely with many common medications including parasiticides, antibiotics and vaccines. For more information, please see the full Prescribing Information at Apoquel.com/pi.Apoquel IndicationsControl of pruritus (itching) associated with allergic dermatitis and control of atopic dermatitis in dogs at least 12 months of age. Cytopoint Indications: Cytopoint has been shown to be effective for the treatment of dogs against allergic dermatitis and atopic dermatitis.
Workup of the allergic dog can be time consuming and difficult. Going through the necessary rule outs is important for allergies, but there are criteria that can heighten your suspicion of atopic dermatitis Check out some criteria that can help you feel more confident about diagnosing a dog with atopic dermatitis!
Welcome to another episode of the Pet Purpose Podcast, the show where my guests and I talk all things pet related… topics that help passionate pet parents take pet parenting to the next level, or topics that are simply of interest for pet parents. Itching in our pets is a very common condition and can be very distressing not only for the affected pet but also for the pet parents. It can be a condition that is emotionally draining, heartbreaking, frustrating, annoying and embarrassing all at the same time.In this episode I unpack:· What an itch is· What the causes of itching are· What some of the signs of itchy skin might look like· How a skin case is worked up· What some of the treatments are· How to manage an itchy pet· And more!Enjoy the episode.This episode is brought to you by Tail Ovation, the online pet store for passionate pet parentsFor show notes and previous episodes, please visit tailovation/podcastLife is better with pets! Disclaimer: The Pet Purpose Podcast contains general information about animal health care conditions and treatments. The information is not advice, and should not be treated as such. You must not rely on the information on the Pet Purpose Podcast as an alternative to animal health care advice from your veterinarian or other professional animal care providers. If you have any specific questions about any animal health care matter you should consult your veterinarian or other professional animal care provider. If you think your pet may be suffering from any animal health condition you should seek immediate veterinary attention specific for your pet. You should never delay seeking veterinary advice specific to your pet, disregard veterinary advice, or discontinue animal health care treatment because of information on the Pet Purpose Podcast. You agree not to hold the representatives, employees, guests or affiliates of the Pet Purpose Podcast, liable for any damages arising from or relating to your reliance on any of the animal health care information provided on the Pet Purpose Podcast. Additionally, you agree not to repeat the animal health care information that you consume on the Pet Purpose Podcast to a third party, as that third party may not have read this disclaimer and understood the caveats involved in receiving the information.
Many people with atopic dermatitis also suffer from allergies and asthma. Kyle Bruner has had all three for as long as he can remember. Kyle joins us with his mother, Jenn Johnson, to share their perspective on living — and thriving — with atopic conditions. National Eczema Association (NEA) NEA is the driving force for an eczema community fueled by knowledge, strengthened through collective action and propelled by the promise for a better future. https://nationaleczema.org/ Contact us: podcast@nationaleczema.org.
Research suggests that the presence of atopy itself may be considered a risk factor for the development of autoimmune diseases in adulthood. Atopic conditions often manifest in the first years of life, so as a clinician treating pediatric patients, how might we intervene in this atopic march during childhood to change outcomes? In this episode of Pathways to Well-Being, our guest Dr. Julie Buckley will discuss the connection between early childhood development, the atopic triad of eczema, allergies, and asthma, and how these atopic conditions might influence autoimmune development later in life.
This episode features Catherine Milley, DVM, Dip ACVD from Animal Dermatology Clinic Portland in Oregon to discuss canine atopic dermatitis. She is my partner in crime in the clinic and passionate about managing complicated canine atopy cases. We go over history, clinical symptoms, antipruritic therapies and allergy testing with immunotherapy.It is a great chat about one of the most common diseases seen by veterinarians!
Halfway up a mountain with his friends, Pikedoo is having a blue day. All of his friends have itchy skin except for him, because he remembered to put on cream.
Pikedoo has virtually no red days at all and he even knows how to control his flare-ups. He feels strong now, and his parents have prepared a great surprise for him...
Pikedoo is on holiday. He spends his time learning to fly, and his feathers become wings. His dream is so close!
Pikedoo learns to live with his eczema and has more and more confidence. He dreams of adventure and of discovering what's on the other side of the green lake.
Pikedoo is at his first dance class, he overcomes his stage fright and learns that there is no shame in having eczema.
It's a red day for Pikedoo today... While pretending to be a scientist he realizes that, to reduce the urge to scratch, he must scratch his skin as little as possible.
It's the second day of the ski trip for Pikédoo and his classmates. When a snow storm leaves them stranded in a shelter, Pikédoo manages his stress perfectly and makes applying the cream into a game.
The day starts badly for Pikedoo, who can't stop scratching, but his teddy Oops is always really creative to distract him.
Pikedoo is a bit scared to go to his friend Pomme's birthday party because of his flare-ups. They are increasingly infrequent, but even so, he is a bit worried. His parents reassure him and he is able to have fun with his friends.
Pikedoo thought it was a blue day, but the itching came back. With Oops, he goes on an investigation to find what is responsible for this unexpected flare-up.
Today Pikedoo is looking forward to reciting his poetry. He is looking forward to it so much that the itching has come back, but luckily his friend Oli reassured him.
This evening Pikedoo tells you how he met Oops, his teddy, who supports him on blue days when he feels good, as well as on red days when he is itchy.
Sometimes we may feel ashamed of our plaques and redness, listen to how Pikédoo explains his disease at playtime in the bamboo forest.
Today, Oops the teddy had a difficult day with lots of itching, discover how Pikédoo relaxed him with a gentle massage.
Pikedoo is very happy today because he's going on a picnic... and he's not itchy anymore. But his friend Oli warns him that he must not lessen his efforts.
Today, discover the first story, the meeting! Get to know Pikedoo, an adorable elephant whose skin plays tricks on him. Not everything is always easy, but the good mood is there!
Ouch! Sometimes when we have a red day, it is difficult to refrain from scratching, but luckily Pikedoo can rely on his friends and his teddy to distract him.
At the school party, Pikedoo is having the time of his life in his french fry costume, but after a day full of emotions, his skin becomes itchy. A soothing massage and everything is better.
Today is a blue day and Pikedoo is having a great time at the beach at the green lake. He puts on cream, and rinses and dries his skin thoroughly after swimming to prevent itching.
Today is the coco football grand final and Pikédoo is worried that sport causes itching. His dad reassures him and tells him that, to be able to run like crazy, all he has to do is hydrate his skin before and after the match.
Pikedoo is at his Grandma's house. There are lots of animals there and he loves playing with them, but his playmates' fur makes him itchy.
Do you think of eczema as “just” a skin rash and that it isn’t that bad? It’s a common viewpoint given the skin doesn’t do what many deem a crucial function each day in the way your bicep might or your knee might, or even your brain might. However, the skin is the body's largest organ and it does in fact serve a crucial function, in fact many, and it is intrinsically connected to everything of which it houses… the gut, the kidney, the intestines, the lungs… It is all connected and today’s episode really dives into how some of those connections can result in skin problems such as eczema.In Today’s Episode We Cover:Why skin creams and steroid solutions cause more harm than goodWhy eczema is really the sign of a dysfunctional immune systemImportant myths and misconceptions for the families and friends of those that suffer from eczema***Join the Facebook Group Here (formerly HH4H): https://bit.ly/IntermittentFastingForHealth***--SOCIAL MEDIA--REBECCA HUGHES BHSc (Nat) CFMP SCU NHAAWebsite: www.melbournefunctionalmedicine.com.auInstagram: https://www.instagram.com/melbournefxmed/--Here is the Bristol ‘poop’ chart: https://www.webmd.com/digestive-disorders/poop-chart-bristol-stool-scale--MATTY LANSDOWNInstagram: https://www.instagram.com/mattylansdown/Linkedin: https://www.linkedin.com/in/matty-lansdown/Join the Facebook Group Here(formerly Health Hacks For Humans):https://bit.ly/IntermittentFastingForHealthWebsite: https://mattylansdown.com/--Got a question? Or maybe even a guest suggestion? Email through - podcast@mattylansdown.com--Thanks for checking out the show. If you enjoyed this episode and want to hear more then please consider subscribing. If you really loved this episode and want to just tell the world about it then please take a screenshot and share it on your Instagram story and be sure to tag me so I know you're tuning in. 5 star ratings and positive reviews really help the podcast too so thank you in advance!......Music credits:Intro/Outro track Tropic Love by "Diviners feat. Contacreast" www.youtube.com/watch?v=DoJfqJsGk8s
Feline allergies can be overwhelming! There are less medications for itchy cats, and a lot of our feline friends won't take oral medications anyway. This emphasizes the importance of working up cat allergies. If we identify the underlying allergy (whether it's flea, food, environmental, or a combination) then we can minimize the use of chronic medications. Making it healthier for the cat, and less frustrating for the owner.Today, Dr. Eva Ganz, DVM, Dip ACVD from the Metropolitan Animal Specialty Hospital in Los Angeles, CA joins me. Dr. Ganz has done research in feline allergies and has a passion for them! We discuss convincing owners to use flea prevention, how to diet trial picky cats, and our take on success of immunotherapy. You wanted more cats, you got it!
Dr Diego Peroni is a specialist in immunology and paediatrics based in Verona, Italy. He is a world-renowned speaker, researcher and author in the field of paediatric immunology, with a specialist interest in childhood respiratory illness and atopic disease.Dr Peroni is the author of more than 250 publications and Associate Editor of a specialist immunology and allergy journal. He is also a member of Società Italiana di Pediatria (SIP), European Respiratory Society (ERS), and the European Academy of Allergy and Clinical Immunology (EAACI), amongst others.Dr Peroni is internationally recognised as a leading expert in paediatric immunology and the gut-immune connection.CLINICAL PEARLS & RESEARCH HIGHLIGHTS FROM THIS PODCAST INCLUDE:· Explore which specific probiotic strains are proven to prevent and treat allergy and atopy· Review mechanistically how the gut microbiota educates and trains an infants' immune system· Discuss early life factors that are critical for establishing risk towards allergy and atopy
VetFolio - Veterinary Practice Management and Continuing Education Podcasts
In this podcast, Dr. Darin Dell, DVM, DACVD reviews key facts about canine atopic dermatitis. The majority of the discussion will be focused on describing current treatment options, providing suggestions for when each option might be best, and explaining how to successfully utilize multi-modal therapy.
Dr Rusty Muse is a registered specialist in veterinary dermatology working both in Perth, in Western Australia, and California, in America. He is an owner and the medical director of the Animal Dermatology Group, a collection of specialist dermatology clinics across the world. He is a diplomat of the American College of Veterinary Dermatology, a member of the American Academy of Veterinary Dermatology, a member of the Dermatology Chapter of the Australian and New Zealand College of Veterinary Scientists, the Southern California Veterinary Medical Association and the Kentucky Veterinary Medical Association. He is also the secretary for the 9th World Congress of Veterinary Dermatology to be held in October 2020 in Sydney. Rusty owns 3 cats. Topics include: Rusty talks us through how he became a veterinarian and how he developed his passion for dermatology. 70% of dogs seen at dermatology clinics have atopic dermatitis. What are the most challenging aspects in managing and treating these cases? The importance of client compliance when it comes to treating allergic dogs. Rusty’s approach to therapy after making a diagnosis of Atopy. The two main defects in atopic dogs are an abnormal immune response and defective skin barrier function. How do we provide short and long term therapies for each of these abnormalities. Dr Muse dives into the ideal way of addressing a defective skin barrier by managing any infections present and using products containing ceramides and oils. Topical or oral use of omega 6 fatty acid. Which one is better? Rusty discusses immunotherapy and explains how allergens are used in his vaccines. The reason Dr Muse recommends a minimum of 3 years of immunotherapy for his patients that may not respond to it in the first year of therapy. How is the world of veterinary dermatology changing in the future? Areas of further research in dermatology. Rusty’s top 3 practical tips to ensure pet owners’ compliance to his treatment plans.
We're back with another dermatological dilemma we confront (nearly) every day: the itching dog! Atopy, insect bite, and food allergies fill our schedules, challenge our teams, and frustrate everyone (especially the poor pet suffering from incessant itching)! This week we're joined by veterinary dermatologist Dr. Candace Sousa. She shares her insights and advice on diagnosing and treating itchy dogs, as well as the latest trends and tips in testing and treatment. Host veterinarians Ernie Ward and Cyndie Courtney have a wide-ranging conversation that will help any veterinary practice more confidently help itching patients. This special podcast episode was brought to you by our friends at Zoetis, makers of Apoquel and Cytopoint. Product information for APOQUEL is available at: www.apoqueldogs.com/apoquel_pi.pdf Zoetis is dedicated to changing the way we approach canine pruritus to protect the bonds that matter most. Visit www.ScienceofStrongerBonds.com for more. Do not use APOQUEL in dogs less than 12 months of age or those with serious infections. APOQUEL may increase the chances of developing serious infections, and may cause existing parasitic skin infestations or pre-existing cancers to get worse.
From the SDPA Annual Summer Dermatology Conference 2018, held June 27 – July 1, 2018 in Seattle, Washington. Topic: Comorbidities in Atopy: Fact or Fiction? Faculty: Robert Sidbury, MD Learning Objectives: 1. Review the components of the atopic march and how to discuss with families 2. Discuss association between ADHD and atopic dermatitis 3. [...]
Have you always wondered what MTHFR means? Today is your lucky day! Welcome the The Tiny Fit Diva Podcast with your host Kylene Terhune! Today Dr. Kendra Becker is joining us on the show. She’s an Integrated Physician practicing in Waterford, Connecticut specializing in the MTHFR gene mutation, Fertility, Autism, Asthma, Allergies and Atopy (eczema).Today’s episode is all about keeping healing at home! She began her career in medicine as a nurse before shifting to a Naturopathic education. Her practice focuses on individuality, pediatrics, and using Epigenetics (the study the environment’s influence on your genes to diagnose and treat). Genes can show whether you have a susceptibility to pesticides, wifi, certain chemicals, anesthesia or pharmaceuticals. This comes down to knowing if you have a sensitivity to and a difficulty processing toxins. Some people do have the ability to detox, so they can get away with eating processed goods like PopTarts. An activated MTHFR, though, means you’ll likely have trouble with Methylation (effectively elimination toxins from the body).Everyone has a bucket to hold toxins that it can’t process and release, and once that bucket gets full, you’ll start to show symptoms of poor health. Everybody is different. Dr. Kendra Becker can help you find out if there is something in your genetic pre-disposition that she could support so that you can live the healthiest life possible based on your environment or help you know how to change your exposures or environment to support your genetics. And, just because you have a certain gene doesn’t mean it’s activated or turned on. The genetics load the gun but the environment pulls the trigger.Dr. Kendra Becker has also written two books:A Delicious Way to Heal the Gut https://www.amazon.com/Delicious-Way-Heal-Gut-Beckers/dp/1519282370/ref=sr_1_1?ie=UTF8&qid=1539022477&sr=8-1&keywords=a+delicious+way+to+heal+the+gutAll You CAN Eat https://www.amazon.com/All-You-CAN-Kendra-Becker/dp/1732297401/ref=sr_1_1?ie=UTF8&qid=1539022527&sr=8-1&keywords=all+you+can+eat+kendra+beckerKylene and Kendra then discuss the recent studies showing links between the MTHFR gene and Down Syndrome. It completely makes sense that if you’re more susceptible to toxicity that we should be able to find this out so we can limit exposure.Kendra talks about her stance on supplements and how they’re not her go-to solution most of the time. For example, if you’re too sensitive to take b12 and folate she knows how to prime the body to be able to absorb those better so you don’t feel sick. You have to introduce things gradually so the person can handle it mentally and their cells can handle it.Links for today’s episode:drkendrabecker.comBe sure to take advantage of Kylene’s free recipe book: 21 Meals in 21 Minutes https://www.thetinyfitdiva.com/21-meals-in-21-minutesThe Tiny Fit Diva Podcast teaches you how to balance your hormones, eat what you want, release the guilt, and have freedom mentally and physically from the restrictive mentality of dieting. Your host, Kylene “The Tiny Fit Diva,” is the right person to help you do it! She is a personal trainer, online health coach, wife, stepmom and a certified FDN practitioner. It’s Kylene's passion to help you achieve and claim your optimum health. Health * Hormones * HappinessEmail Kylene at kylenet@thetinyfitdiva.com
Does living in a 'westernised' country put you at greater risk for allergy and atopy? The science and statistics are saying yes. The major drivers for allergy and atopy are multifactorial and complex but indeed, almost all circumstances relate back to modernisation and the industrial revolution. Society's obsession with sterilisation and being 'germ-free' has put us at risk. Now, in Australia, 25% of the population can expect to be diagnosed with allergy at some point in their life. Today we welcome back Nicole Bijlsma, author of "Healthy Homes; Healthy Families" and leading environmental health expert who takes us through these varied risks and how we can intervene in practical ways to minimise the incidence of allergy and atopy in our modern lives. Find today's show notes and transcript here: https://www.fxmedicine.com.au/content/practical-interventions-allergy-and-atopy-nicole-bijlsma *****DISCLAIMER: The information provided on FX Medicine is for educational and informational purposes only. The information provided is not, nor is it intended to be, a substitute for professional advice or care. Please seek the advice of a qualified health care professional in the event something you learn here raises questions or concerns regarding your health.*****
The ImmuoModulators provide a primer on mucosal defenses, and explain how sensitizing female mice to food allergens prevents allergic reactions in their offspring. Hosts: Vincent Racaniello, Stephanie Langel, and Cynthia Leifer Become a patron of Immune! Links for this episode Food Allergy(Nat Rev Dis Prim) Maternal allergen sensitization(J Exp Med) Image credit Letters readon Immune #5 Music by Steve Neal. Immune logo image by Blausen Medical. Send your immunology questions and comments to immune@microbe.tv
Chemokines and their receptors are involved in many aspects of immunity. Chemokine CX3CL1, acting via its receptor CX3CR1, regulates monocyte migration and macrophage differentiation as well as T cell-dependent inflammation. Two common, nonsynonymous polymorphisms in CX3CR1 have previously been shown to alter the function of the CX3CL1/CX3CR1 pathway and were suggested to modify the risk for asthma. Using matrix-assisted laser desorption/ionization time-of-flight technology, we genotyped polymorphisms Val249Ile and Thr280Met in a cross-sectional population of German children from Munich (n = 1,159) and Dresden ( n = 1,940). For 249Ile an odds ratio of 0.77 (95% confidence interval 0.63-0.96; p = 0.017) and for 280Met an odds ratio of 0.71 ( 95% confidence interval 0.56-0.89; p = 0.004) were found with atopy in Dresden but not in Munich. Neither polymorphism was associated with asthma. Thus, amino acid changes in CX3CR1 may influence the development of atopy but not asthma in German children. Potentially, other factors such as environmental effects may modify the role of CX3CR1 polymorphisms. Copyright (c) 2007 S. Karger AG, Basel.
Background: Maternal atopic background and stimulation of the adaptive immune system with allergen interact in the development of allergic disease. Stimulation of the innate immune system through microbial exposure, such as activation of the innate Toll-like- receptor 2 (TLR2), may reduce the development of allergy in childhood. However, little is known about the immunological effects of microbial stimulation on early immune responses and in association with maternal atopy. Methods: We analyzed immune responses of cord blood mononuclear cells ( CBMC) from 50 healthy neonates ( 31 non-atopic and 19 atopic mothers). Cells were stimulated with the TLR2 agonist peptidoglycan (Ppg) or the allergen house dust mite Dermatophagoides farinae (Derf1), and results compared to unstimulated cells. We analyzed lymphocyte proliferation and cytokine secretion of CBMC. In addition, we assessed gene expression associated with T regulatory cells including the transcription factor Foxp3, the glucocorticoid-induced TNF receptor ( GITR), and the cytotoxic lymphocyte antigen 4 (CTLA4). Lymphocyte proliferation was measured by H-3-Thymidine uptake, cytokine concentrations determined by ELISA, mRNA expression of T cell markers by real-time RT-PCR. Results: Ppg stimulation induced primarily IL-10 cytokine production, in addition to IFN-gamma, IL-13 and TNF-alpha secretion. GITR was increased following Ppg stimulation ( p = 0.07). Ppg- induced IL-10 production and induction of Foxp3 were higher in CBMC without, than with maternal atopy ( p = 0.04, p = 0.049). IL-10 production was highly correlated with increased expression of Foxp3 ( r = 0.53, p = 0.001), GITR ( r = 0.47, p = 0.004) and CTLA4 ( r = 0.49, p = 0.003), independent of maternal atopy. Conclusion: TLR2 stimulation with Ppg induces IL-10 and genes associated with T regulatory cells, influenced by maternal atopy. Increased IL-10 and Foxp3 induction in CBMC of non-atopic compared to atopic mothers, may indicate an increased capacity to respond to microbial stimuli.
Background: The interleukin (IL) 4/IL13 pathway is involved in the regulation of IgE production associated with atopic diseases. Numerous polymorphisms have been identified in the coding region of the IL4 receptor alpha chain (IL4Ra) and previous association studies have shown conflicting results. Based on their putative functional role, polymorphisms A148G, T1432C and A1652G, located in the coding region of IL4Ra, were selected for association and haplotype studies in a large German population sample (n = 1,120). Methods: Genotyping was performed using allele-specific PCR and restriction-enzyme-based assays. Haplotypes were estimated, and population-derived IgE percentiles (50% IgE >60 IU/ml, 66% IgE >115 IU/ml and 90% IgE >457 IU/ml) were calculated as outcome variables in a haplotype trend regression analysis. Results: In our population, only polymorphism T1432C showed a trend for a protective effect against atopic rhinitis ( odds ratio, OR: 0.52, 95% confidence interval, CI: 0.26 - 1.02, p = 0.05). When haplotypes were calculated, one haplotype was significantly associated with elevated serum IgE levels at the 50th percentile ( OR 1.60, 95% CI 1.08 - 2.37, p = 0.02). Conclusions: These data indicate that IL4Ra polymorphisms, although suggested to be functionally relevant by in vitro studies, have only a minor influence on IgE regulation in our large population sample. Copyright (C) 2004 S. Karger AG, Basel.