Podcast appearances and mentions of dave clarke

Réécoutez Maxximum DJ's avec Dave Clarke du samedi 14 juin 2025

The 2025 NBA Finals have officially gone off-script — and the Indiana Pacers are the story of the postseason. In this episode of Missing the Point, Dave Clarke and Bob Kelly dive into how Indiana now holds a 2-1 series lead over the heavily favored Oklahoma City Thunder.We break down Tyrese Haliburton's incredible rise as the unlikely face of the NBA Finals, his clutch game-winners, and whether he's officially entered the top-10 NBA player conversation. Dave and Bob also examine how Rick Carlisle is coaching circles around the competition — drawing parallels to his 2011 Dallas Mavericks run when he shocked the world against LeBron's Heat.Beyond Haliburton, the Pacers' balanced team-first approach is on full display. We spotlight the huge performances from Andrew Nembhard, Myles Turner, Pascal Siakam, Benedict Mathurin, Obi Toppin, and TJ McConnell — and explain how Indiana's deep bench and unselfish ball movement have become the secret weapon against OKC's youth and athleticism.We also analyze the Oklahoma City Thunder's struggles as Shai Gilgeous-Alexander faces Carlisle's adjustments, Chet Holmgren gets exposed in the post, and Mark Daigneault tries to keep his young roster composed under Finals pressure. Plus, we debate whether OKC's youth and future assets could ironically work against them in this moment.Other topics include:Can Halliburton surpass Reggie Miller as the most important Pacer ever?How Indiana's basketball culture fuels this underdog run.How this NBA Finals compares to historic upsets like the 2011 Mavericks vs Heat.Joe Mazzulla's failures in contrast to Carlisle and Daigneault.Why the NBA Playoffs 2025 may end with one of the biggest Finals shocks in league history.If you're a fan of NBA Finals analysis, NBA Playoffs 2025 coverage, Tyrese Haliburton's rise, Indiana Pacers vs OKC Thunder breakdowns, and NBA history, you don't want to miss this episode.

Dave Clarke's Saga Series Episode 131

Réécoutez le FG mix spécial techno avec Dave Clarke du jeudi 12 juin 2025

Réécoutez Maxximum DJ's avec Dave Clarke du samedi 7 juin 2025

On this episode of Missing the Point, Dave Clarke and Mike Marcangelo break down one of the biggest media shakeups in modern basketball: Inside the NBA is moving from TNT to ESPN. What does this mean for the most beloved sports show in TV history? Will ESPN let Charles Barkley, Ernie Johnson, Shaq, and Kenny do their thing—or will they butcher the format with hot takes and overproduced segments? The guys also debate whether Stephen A. Smith will join the cast—and if so, will he respect the legacy or hijack it?Then we dive into the Knicks' shocking firing of Tom Thibodeau after reaching the Eastern Conference Finals. Could this be about a potential Kevin Durant trade? Plus, we break down Joe Mazzulla's coaching issues in Boston, why Jayson Tatum's injury may close the Celtics' title window, and whether it's time for a rebuild.Also on the docket:Anthony Edwards' polarizing playoff performanceRudy Gobert's future in MinnesotaKevin Durant trade speculationNBA Finals preview: Thunder vs. PacersWhy Halliburton might struggle vs. OKC's lengthCan Shai Gilgeous-Alexander lead OKC to a title?This is one of our most wide-ranging and unfiltered episodes yet—no networks, no fluff, just real basketball talk.

Réécoutez Maxximum DJ's avec Dave Clarke du samedi 31 mai 2025

Réécoutez Maxximum DJ's avec Dave Clarke du samedi 24 mai 2025

On this week's episode of Missing the Point, hosts Dave Clarke, Rayshawn Buchanan, Mike Marcangelo, and Bob Kelly deliver an unfiltered and in-depth breakdown of the 2025 NBA Playoffs. From the Western Conference Finals to the Celtics' crushing playoff exit, we're covering all the biggest headlines in professional basketball.We begin in the West, where the Oklahoma City Thunder continue their incredible postseason run after a dominant Game 1 win over the Minnesota Timberwolves. With Shai Gilgeous-Alexander playing at an MVP level and key role players like Alex Caruso and Chet Holmgren stepping up, the Thunder might just be the favorites to win it all. We also evaluate Anthony Edwards' playoff struggles and what Minnesota needs to adjust to stay competitive.Over in the East, the Indiana Pacers shocked the New York Knicks with a wild Game 1 comeback. The crew discusses Tyrese Haliburton's evolution into a franchise cornerstone, the Knicks' late-game collapse, and how this thrilling series could play out.Then, it's time for a brutally honest postmortem on the Boston Celtics. Jayson Tatum's devastating ankle injury, Joe Mazzulla's controversial coaching decisions, and the looming financial pressure on Boston's roster all come under scrutiny. Is it time to blow it up or regroup for another run?Whether you're a Celtics fan, a Thunder believer, or just a diehard NBA junkie, this is the playoff reaction episode you don't want to miss.

Dave Clarke's Saga Series Episode 130

Another Life  Show - May 2025 presented by Dave Lazenby.Welcome to Another Life: Sheffield's Progressive PulseBorn in 2022, Another Life emerged with a mission to infuse Sheffield's nightlife with the vibrant sounds of melodic techno and progressive house. Founded by local talents Dan Bumby, Jon Towell, and Dave Lazenby, the collective has rapidly become a cornerstone of the city's electronic music scene.Meet the FoundersDan BumbyA seasoned DJ and producer from Sheffield, Dan has shared stages with industry giants like Hot Since 82, Alan Fitzpatrick, Dave Clarke, and Dave Seaman. As part of the techno duo Dan & Dan and house project GoldRed, he's also the co-owner of 64k Recordings Ibiza and Barbershop Recordings. His tracks have graced labels such as Perfecto, Frequenza, and King Street Sounds. Jon TowellJon has carved out a solid reputation on the underground scene over the years. Recently holding summer residencies at Hotel Garbi in Ibiza along with guest slots on Ibiza Sonica Radio, as well as playing legendary venues on the island such as Es Paradis and Ibiza Rocks. In the last 12 months, Jon has been making waves in the Beatport charts with several top 10 positions, gaining support from the likes of John Digweed, Black Coffee, Armin Van Buuren, Damian Lazarus, and Paco Osuna. With a busy schedule of track releases in 2024, Jon has already signed to respected record labels such as Krafted Underground and many more. Dave LazenbyA co-founder of Another Life, Dave has been instrumental in shaping its identity. He's performed at various club nights and festivals across the UK, supporting progressive house luminaries like Dave Seaman, Quivver, Steve Parry, and Lexicon Avenue. Internationally, he's graced stages in Ibiza at venues like Es Paradis and Ibiza Rocks Bar. Venturing into production, Dave has released tracks such as "The Face" and "Underground" in collaboration with Jon Towell. Elevating Sheffield's Electronic SceneAnother Life has been pivotal in bringing world-class DJs to Sheffield. Notable events include performances by legends like Dave Seaman and Steve Parry at Factory Floor in April 2025. Looking ahead, they're set to host a daytime event on August 23rd featuring Anthony Pappa & Four Candles, promising a high-energy experience for attendees. Tune In to PHUKJoin us on PHUK as we delve into the sonic journey of Another Life. Expect a curated mix of their resident DJs' sets, exclusive interviews, and insights into upcoming events. This show is a celebration of Sheffield's thriving electronic music culture and the visionaries propelling it forward.Dave's May Tracklist:DAANN - Natira (Original Mix)[AH Digital]Will DeKeizer - Rocket Jam (Original Mix)[Plattenback] J. Khobb - Sleep Walker (Original Mix)[Future Avenue]Jon Towell - Factory Floor (Original Mix) [Keep Thinking Music]Madloch and Subnode - A Fading Dream (Figueras Remix)[Forwrd Music]DJ Zombie & Guy Maayan - Artificial Vibez (Weird Sounding Dude Remix)[Where The Shadow Ends]Gaston Rodriguez (AR) - Eclipsed (VegaZ SL Remix)[SINCITY]Lucho Bragagnolo - Monochrome (Casnik Remix)[Traful]Morris (AR) - Surge (Original Mix)[Future Avenue]Redspace - Side Effect (Original Mix)[Protagonist Recordings]BRIAN DE SANTIS - Casarena (Iovino Remix) [AH Digital]Shayan Pasha & Redspace - Pantheon (Original Mix) [WARPP]Quivver - The Price of Time (Orignal Mix) [Controlled Substance]

Réécoutez Maxximum DJ's avec Dave Clarke du samedi 17 mai 2025

Tom BourneTom Bourne is the Creative Director of Select First, a small and highly flexible, full-service PR and marketing agency that's been helping interior and built environment brands stand out for over 25 years. Based in Tunbridge Wells in the southeast of the UK, they work with flooring and interiors clients from the UK and across Europe. Involved in direct marketing, electronic campaigns and traditional PR daily, Tom works with clients on numerous specialised projects, including brochure materials, website development, and integrated communications campaigns I spoke to Tom via Zoom in May 2025 a few days before Clerkenwell Design Week.. In this episode, we discover how Tom developed his skills in the publishing industry.  The importance of authenticity in marketing.  Why manufacturers should take responsibility for the full cycle of their products and their environmental impact.  How informed decisions and understanding definitions helps make sustainable choices. And why, if you really want to understand products, you should go on a factory visit.   LinksSelect First website https://www.selectfirst.com/ LinkedIn Tom https://www.linkedin.com/in/tombournepr/?originalSubdomain=uk Select First https://www.linkedin.com/company/select-first-limited/posts/?feedView=all 1% for the Planethttps://www.onepercentfortheplanet.org The Anti-greenwash charterhttps://antigreenwashcharter.org/ Clerkenwell Design Week-The Gallery Clerkenwellhttps://www.clerkenwelldesignweek.com/exhibitors/gallery   How to be a kick-ass Interior Designer. Come and join us on the Interior Design BA(Hons) course at the University of Plymouth. https://www.plymouth.ac.uk/courses/undergraduate/ba-interior-design Thanks to Dave Clarke from @iamthehow (http://www.iamthehow.com) for production support and invaluable advice in the setting up of this Podcast. Kay Hanson (https://www.instagram.com/kay_v_hanson/) for her planning support and co-hosting for these and our educational podcasts for the University of Plymouth Mark Frith (https://www.markfrith.uk/) for composing the music and all your support and advice along the way. I'd really like to hear feedback on the podcast.  Leave a comment or get in touch via the website or Instagram. Website http://www.multistorythinking.com/contact Instagram https://www.instagram.com/forster_jonathan/ Thanks for listening.  Bye for now Research and collaboration

Réécoutez Maxximum DJ's avec Dave Clarke du samedi 10 mai 2025

On this jam-packed episode of Missing the Point, hosts Dave Clarke and Rayshawn Buchanan deliver a passionate, in-depth instant reaction to the Boston Celtics' crushing Game 4 loss to the New York Knicks in the 2025 NBA Playoffs. The 121-113 defeat at Madison Square Garden puts the Celtics down 3-1 in the Eastern Conference Semifinals—and the injury to Jayson Tatum may have just ended their championship dreams.We dissect every pivotal moment of the game, from Tatum's devastating lower leg injury and what it means for his future in the NBA, to Jaylen Brown's lackluster postseason performance, and Kristaps Porzingis' inability to impact the series. With the Celtics' title hopes hanging by a thread, can they bounce back in Game 5 at TD Garden? Or is this the heartbreaking end to their 2025 playoff run?This episode also dives into Boston's long-term future: potential offseason trades, including whether Jaylen Brown should be moved, how Jrue Holiday and Derrick White fit into the big picture, and the chances of Porzingis being part of the plan going forward. We reflect on past NBA postseason injuries that changed the course of franchises and discuss whether the Celtics are witnessing the end of an era.From raw emotion to honest critique, this episode is must-listen content for any Celtics die-hard, NBA fan, or basketball junkie looking for deep playoff analysis and real-time reaction.

Dave Clarke's Saga Series Episode 129

This week on Missing the Point, hosts Dave Clarke, Michael Marcangelo, and Bob Kelly bring you an unfiltered, in-depth breakdown of the 2025 NBA Playoffs — from Nikola Jokic's dominance to the Celtics' catastrophic collapse against the Knicks.We start in the Western Conference, dissecting the Los Angeles Clippers' embarrassing Game 7 loss to the Denver Nuggets. James Harden disappears again when it matters most, while Nikola Jokic puts on a clinic with a monster 42-point, 22-rebound performance that proves why he's the best player on the planet. We also analyze Jamal Murray's resurgence and whether the Oklahoma City Thunder can find any answers for Jokic's unstoppable game. Plus, we show love to Russell Westbrook and debate if his comic relief on the court might be hiding real value in the Nuggets' playoff run.Then we preview the Timberwolves vs. Warriors showdown — Can Anthony Edwards cement his superstar status? Will Draymond Green's volatility derail Golden State? Is Steph Curry still that guy? We also assess Buddy Hield's surprising impact and Jonathan Kuminga's disappearing act.Over in the East, we react to the Boston Celtics blowing a 20-point lead to the New York Knicks. What's going on with Jayson Tatum's shot selection? Can a banged-up Jaylen Brown still lead this team? And is Kristaps Porzingis healthy enough to contribute? We also cover Donovan Mitchell's explosive playoff form in the Cavs vs. Pacers series, Evan Mobley's rise, and whether Tyrese Haliburton and the Pacers are the biggest dark horse in the Eastern Conference.If you're obsessed with NBA Playoff basketball, hot takes, and sharp analysis, this is your episode.

Réécoutez Maxximum DJ's avec Dave Clarke du samedi 3 mai 2025

In this jam-packed episode of Missing the Point, hosts Dave Clarke, Rayshawn Buchanan, and Bob Kelly dive into two of the biggest stories in sports right now: the 2025 NFL Draft and the high-stakes NBA Playoffs. We deliver a full breakdown of the New England Patriots' strong draft strategy, including the selection of offensive tackle Will Campbell, along with analysis of the Chicago Bears, Dallas Cowboys, Jacksonville Jaguars, and more. From team needs to best available talent, we cover all the key picks and assign grades with zero fluff.Then we shift to the NBA Playoffs, where the Boston Celtics have taken control after eliminating the Orlando Magic. Jason Tatum's superstar leap takes center stage, while we question Sam Hauser's playoff impact and discuss Joe Mazzulla's evolution as a coach. In the West, we analyze the Lakers' struggles (pre-elimination), assess the Timberwolves' physicality, and ask whether Anthony Edwards has arrived as a top-tier star. Is Jamal Murray's resurgence enough for Denver? Is James Harden dragging the Clippers down? And has Giannis played his final game in a Milwaukee Bucks uniform?We also debate potential trades, coaching failures, and what's next for teams like the Memphis Grizzlies and Miami Heat.Subscribe for fresh episodes every week with no-nonsense sports talk and sharp analysis.

Réécoutez Maxximum DJ's avec Dave Clarke du samedi 26 avril 2025

Dave Clarke's Saga Series Episode 128

Terence Fixmer's music has the remarkable ability to not only set feet in motion on the dance floor but also resonate deeply with the searching soul, all while maintaining a profound musical depth and integrity. With a career spanning over two decades, he has released numerous albums and EPs on some of the most prestigious techno labels. His remixing talents have extended to tracks from industry giants like Depeche Mode, Yann Tiersen, Sven Väth, Dave Clarke, Front 242, Nitzer Ebb, Indochine, and more. Terence Fixmer is renowned for the quality of his live performances, gracing renowned clubs and festivals worldwide. Chapter 1: 1998-2007. In 1998, Terence established his own label, Planete Rouge. From 1999 to 2007, he gained worldwide recognition with the release of his debut album, "Muscle Machine," under DJ Hell's legendary International Deejay Gigolos imprint. In 2002, Fixmer joined forces with Nitzer Ebb's lead singer, Douglas McCarthy, to form Fixmer/McCarthy. Together, they released two full-length albums that pushed the boundaries of Techno EBM to the maximum. The album "Fixmer McCarthy Between the Devil" has earned its place as a revered classic, and the band has become iconic in the Techno EBM scene.Fixmer/McCarthy earned respect in the global scene for their unique way of creating truly pioneering sound fusions by elegantly blending the aggression of Techno Body Music and the sensuality of Electronica. Chapter 2: 2007-2015 Fixmer continued to expand the horizons of modern techno, releasing albums and EPs under his own name as well as various alter egos. His works found homes on highly respected techno labels such as Electric De Luxe, Prologue, Jealous God, CLR (including the "Depth Charged" album in 2014), Aufnahme + Wiedergabe. Chapter 3: 2015-2020 Terence Fixmer continued to evolve his sound in 2015. His EP "Aktion Mekanik," was reissued on Ostgut Ton, marking his entry into the Ostgut Ton family—the flagship label of Berlin's Berghain club. He subsequently released various EPs on Ostgut Ton ( Force EP, Devil May Care EP) and his album "Through the Cortex LP ." in 2017. Chapter 4: 2020- Terence produced music for Thomas Cohen (formerly singer of Scum) with tracks like "Braid" and "Chain of Love" on Mute Records.Additionally, he signed with the legendary label Mute Records, renowned for its roster of innovative and influential artists.  In 2022, he released his first album on Mute Records titled "Shifting Signals" . His music has been used by Fashion brand, such as Prada, Raf Simons, Zegna... Terence Fixmer's unwavering drive to craft experimental, mind-bending, and relentless sounds continues to transcend the boundaries of the musical mainstream, solidifying his place as a visionary within the techno and electronic music landscape. Tracklist via -Spotify: bit.ly/SRonSpotify -Reddit: www.reddit.com/r/Slam_Radio/ -Facebook: bit.ly/SlamRadioGroup Archive on Mixcloud: www.mixcloud.com/slam/   Subscribe to our podcast on -iTunes: apple.co/2RQ1xdh -Amazon Music: amzn.to/2RPYnX3 -Google Podcasts: bit.ly/SRGooglePodcasts -Deezer: bit.ly/SlamRadioDeezer   Keep up with SLAM: https://fanlink.tv/Slam  Keep up with Soma Records: https://linktr.ee/somarecords    For syndication or radio queries: harry@somarecords.com & conor@glowcast.co.uk Slam Radio is produced at www.glowcast.co.uk

Welcome to "Missing the Point," hosted by Dave Clarke and Michael Marcangelo! In this exciting and in-depth breakdown of the 2025 NBA Playoffs, we dive head-first into every critical first-round series, analyzing all the storylines and superstar performances. Hear our detailed reaction to the Oklahoma City Thunder's record-breaking dominance over the Memphis Grizzlies and why Shai Gilgeous-Alexander could lead them to the NBA Finals. We discuss why LeBron James, Luka Dončić, and the struggling Los Angeles Lakers are in trouble against Anthony Edwards' surging Minnesota Timberwolves. Plus, we examine Nikola Jokic's late-game troubles against Kawhi Leonard and the high-powered LA Clippers.In the Eastern Conference, we cover everything from the Boston Celtics' injury woes with stars Jayson Tatum and Jaylen Brown to how their depth can carry them against the gritty Orlando Magic. Explore detailed analyses of Donovan Mitchell's vintage performance for the Cleveland Cavaliers against Jimmy Butler's Miami Heat, why Tyrese Haliburton and the Indiana Pacers have shocked Giannis Antetokounmpo and the Milwaukee Bucks, and why the Pistons-Knicks series is quickly becoming a must-watch battle featuring Cade Cunningham and Jalen Brunson.Don't miss our expert insights, bold playoff predictions, and hot takes that set the stage for a thrilling postseason!

Réécoutez Maxximum DJ's avec Dave Clarke du samedi 19 avril 2025

Dave Clarke's Saga Series Episode 127

We're officially on the RadCast Network, and we're celebrating by diving headfirst into some delicious NFL Draft madness. This week on Missing the Point, Dave Clarke and Michael Marcangelo break down Mel Kiper's latest mock draft, focusing on how it impacts two franchises in rebuild mode: the Chicago Bears and the New England Patriots.We explore best-case draft scenarios, wild hypotheticals (including Travis Hunter and Abdul Carter falling), and what Dave and Mike think the Pats and Bears should do at picks 4 and 10. You'll also hear strong takes on Tyler Warren, Ashton Jeanty, Cam Ward, Will Campbell, Trayveon Henderson, and why the running back renaissance may be upon us.Plus, the guys debate the end of the 49ers' title window, the Rams' draft strategy, and Dave's irrational hatred for Aaron Rodgers—especially if he ends up quarterbacking the Pittsburgh Steelers to a Super Bowl. You don't want to miss the laughs, takes, and unfiltered chaos as we prep for our upcoming Mock Draft Game Show.⚡ Subscribe now and stay ahead of the curve as the NFL Draft nears.—

The Boston Celtics are officially in playoff mode — riding an 8-game winning streak and going 23-4 since January 30th — and on this week's episode of Missing the Point, hosts Rayshawn Buchanan and Dave Clarke ask the question every NBA fan is thinking: Are the Celtics peaking at just the right time? We dive deep into the Celtics' recent dominance and break down the biggest storylines heading into the NBA Playoffs. From Jayson Tatum's MVP-level performance to Kristaps Porzingis' evolution into the ultimate stretch five, this episode is packed with insight, hot takes, and real analysis for Celtics fans and hoop heads alike.

Despite advances in epilepsy management, disparities and lack of inclusion of many people with epilepsy are associated with increased morbidity and mortality. Improving awareness and promoting diversity in research participation can advance treatment for underserved populations and improve trust. In this episode, Teshamae Monteith, MD, PhD, FAAN speaks Dave F. Clarke, MBBS, FAES, author of the article “Diversity and Underserved Patient Populations in Epilepsy,” in the Continuum® February 2025 Epilepsy issue. Dr. Monteith is a Continuum® Audio interviewer and an associate editor of Continuum® Audio and an associate professor of clinical neurology at the University of Miami Miller School of Medicine in Miami, Florida. Dr. Clarke is the Kozmetsky Family Foundation Endowed Chair of Pediatric Epilepsy and Chief or Comprehensive Pediatric Epilepsy Center, Dell Medical School at the University of Texas at Austin in Austin, Texas. Additional Resources Read the article: Diversity and Underserved Patient Populations in Epilepsy Subscribe to Continuum: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @HeadacheMD Full episode transcript available here Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum, the premier topic-based neurology clinical review and CME journal from the American Academy of Neurology. Thank you for joining us on Continuum Audio, which features conversations with Continuum's guest editors and authors who are the leading experts in their fields. Subscribers to the Continuum Journal can read the full article or listen to verbatim recordings of the article and have access to exclusive interviews not featured on the podcast. Please visit the link in the episode notes for more information on the article, subscribing to the journal, and how to get CME. Dr Monteith: This is Dr Teshamae Monteith. Today I'm interviewing Dr Dave Clarke about his article on diversity and underserved patient populations in epilepsy, which appears in the February 2025 Continuum issue on epilepsy. So why don't you introduce yourself to our audience? Dr Clarke: Sure. My name is Dr Dave Clarke, as alluded to. I'm presently at the University of Texas in Austin, originating from much farther south. I'm from Antigua, but have been here for quite a while working within the field in epilepsy surgery, but more and more getting involved in outreach, access to care, and equity of healthcare in epilepsy. Dr Monteith: And how did you get involved in this kind of work? Dr Clarke: That's an amazing question. You know, I did it in a bit of a inside out fashion. I initially started working in the field and trying to get access to persons in the Caribbean that didn't have any neurological care or investigative studies, but very quickly realized that persons around the corner here in Texas and wherever I've worked have had the exact same problems, getting access via fiscal or otherwise epilepsy care, or geographically getting access, with so few having neurologists close at hand. Therefore, I started working both on a regional, national, and it transcended to a global scale. Dr Monteith: Wow, so you're just everywhere. Dr Clarke: Well, building bridges. I've found building bridges and helping with knowledge and garnering knowledge, you can expand your reach without actually moving, which is quite helpful. Dr Monteith: Yeah. So why don't you tell us why you think this work is so important in issues of diversity, underserved populations, and of course, access to epilepsy care? Dr Clarke: Sure, not a problem. And I think every vested person in this can give you a different spiel as to why they think it's important. So, I'll add in a few facts pertaining to access, but also tell you about why I think personally that it's not only important, but it will improve care for all and improve what you believe you could do for a patient. Because the sad thing is to have a good outcome in the United States presently, we have over three hundred epilepsy centers, but they have about eight or nine states that don't have any epilepsy centers at all. And even within states themselves, people have to travel up to eight hours, i.e., in Texas, to get adequate epilepsy care. So that's one layer. Even if you have a epilepsy center around the corner, independent of just long wait times, if you have a particular race or ethnicity, we've found out that wait may be even longer or you may be referred to a general practitioner moreso than being referred to an epilepsy center. Then you add in layers of insurance or lack thereof, which is a big concern regardless of who you are; poverty, which is a big concern; and the layers just keep adding more. Culture, etcetera, etcetera. If you could just break down some of those barriers, it has been shown quite a few years ago that once you get to an epilepsy center, you can negate some of those factors. You can actually reduce time to access and you can improve care. So, that's why I'm so passionate about this, because something could potentially be done about it. Dr Monteith: That's cool. So, it sounds like you have some strategies, some strategies for us. Dr Clarke: Indeed. And you know, this is a growth and this is a learning curve for me and will be for others. But I think on a very local, one-to-one scale, the initial strategy I would suggest is you have to be a good listener. Because we don't know how, when, where or why people are coming to us for their concerns. And in order to judge someone, if they may not have had a follow-up visit or they may not have gotten to us after five medications, the onus may not have been on that person. In other words, as we learned when we were in medical school, history is extremely important, but social history, cultural history, that's also just as important when we're trying to create bridges. The second major thing that we have to learn is we can't do this alone. So, without others collaborating with us outside of even our fields, the social worker who will engage, the community worker who will discuss the translator for language; unless you treat those persons with respect and engage with those persons to help you to mitigate problems, you'll not get very far. And then we'll talk about more, but the last thing I'll say now is they have so many organizations out there, the Institute of Medicine or the International League Against Epilepsy or members of the American Epilepsy Society, that have ways, ideas, papers, and articles that can help guide you as to how better mitigate many of these problems. Dr Monteith: Great. So, you already mentioned a lot of things. What are some things that you feel absolutely the reader should take away in reading your article? You mentioned already listening skills, the importance of interdisciplinary work, including social work, and that there are strategies that we can use to help reduce some of this access issues. But give me some of the essential points and then we'll dive in. Dr Clarke: OK. I think first and foremost we have to lay the foundation in my mind and realize what exactly is happening. If you are Native American, of African descent, Hispanic, Latinx, geographically not in a region where care can be delivered, choosing one time to epilepsy surgery may be delayed twice, three, four times that of someone of white descent. If you are within certain regions in the US where they may have eight, nine, ten, fourteen epilepsy centers, you may get to that center within two to three years. But if you're in an area where they have no centers at all, or you live in the Dakotas, it may be very difficult to get to an individual that could provide that care for you. That's very, very basic. But a few things have happened a few years ago and even more recently that can help. COVID created this groundswell of ambulatory engagement and ambulatory care. I think that can help to mitigate time to get into that person and improving access. In saying that, there are many obstacles to that, but that's what we have to work towards: that virtual engagement and virtual care. That would suggest in some instances to some persons that it will take away the one-to-one care that you may get with persons coming to you. But I guarantee that you will not lose patients because of this, because there's too big a vacuum. Only 22% of persons that should actually get to epilepsy centers actually get to epilepsy centers. So, I think we can start with that foundation, and you can go to the article and learn a lot more about what the problems are. Because if you don't know what the problems are, you can't come up with solutions. Dr Monteith: Just give us a few of the most persistent inequities and epilepsy care? Dr Clarke: Time to seeing a patient, very persistent. And that's both a disparity, a deficiency, and an inequity. And if you allow me, I'll just explain the slight but subtle difference. So, we know that time to surgery in epilepsy in persons that need epilepsy surgery can be as long as seventeen years. That's for everyone, so that's a deficiency in care. I just mentioned that some sociodemographic populations may not get the same care as someone else, and that's a disparity between one versus the other. Health equity, whether it be from NIH or any other definition, suggests that you should get equitable care between one person and the other. And that brings in not only medical, medicolegal or potential bias, that we may have one person versus the other. So, there's a breakdown as to those different layers that may occur. And in that I'm telling you what some of the potential differences are. Dr Monteith: And so, you mentioned, it comes up, race and ethnicity being a major issue as well as some of the geographic factors. How does that impact diagnosis and really trying to care for our patients? Dr Clarke: So again, I'm going to this article or going to, even. prior articles. It has been shown by many, and most recently in New Jersey, that if you're black, Hispanic, Latin- Latinx, it takes you greater than two times the time to surgery. Reduced time to surgery significantly increases morbidity. It potentially increases mortality, as has been shown by a colleague of mine presently in Calgary. And independent of that, we don't look at the other things, the other socially related things. Driving, inability to work, inability to be adequately educated, the stigma related to that in various cultures, various countries. So, that deficit not only increased the probability of having seizures, but we have to look at the umbrella as to what it does. It significantly impacts quality of life of that individual and, actually, the individuals around them. Dr Monteith: So, what are some of these drivers, and how can we address them, or at least identify them, in our clinic? Dr Clarke: That's a question that's rather difficult to answer. And not because there aren't ideas about it, but there's actually mitigating those ideas or changing those ideas we're just presently trying to do. Although outlines have been given. So, in about 2013, the federal government suggested outlines to improve access and to reduce these inequities. And I'll just give you a few of them. One of those suggestions was related to language and having more improved and readily available translators. Something simple, and that could actually foster discussions and time to better management. Another suggestion was try to train more persons from underserved populations, persons of color. Reason being, it has been shown in the social sciences and it is known in the medical sciences that, if you speak to a person of similar culture, you tend to have a better rapport, you tend to be more compliant, and that track would move forward, and it reduces bias. Now we don't have that presently, and I'm not sure if we'll have that in the near future, although we're trying. So then, within your centers, if you have trainings on cultural sensitivity, or if you have engagements and lectures about how you can engage persons from different populations, those are just some very simple pearls that can improve care. This has been updated several times with the then-Institute of Medicine in 2012, 2013, they came out with, in my mind, a pretty amazing article---but I'm very biased---in which they outline a number of strategic initiatives that could be taken to improve research, improve clinical care, improve health equity through health services research, to move the field forward, and to improve overall care. They updated this in 2020, and it's a part of the 2030 federal initiative not only for epilepsy, but to improve overarching care. All of this is written in bits and pieces and referenced in the article. To add icing on top, the World Health Organization, through advocacy of neurological groups as well as the International League Against Epilepsy and the AES, came out with the Intersectoral Action Plan on Epilepsy and Other Neurological Diseases, which advocates for parallel improvement in overall global care. And the United States have signed on to it, and that have lit a fire to our member organizations like the American Epilepsy Society, American Academy of Neurology, and others, trying to create initiatives to address this here. I started off by saying this was difficult because, you know, we have debated epilepsy care through 1909 when the International League against Epilepsy was founded, and we have continually come up with ways to try and advance care. But this have been the most difficult and critical because there's social dynamics and social history and societal concerns that have negated us moving forward in this direction. But fortunately, I think we're moving in that direction presently. That's my hope. And the main thing we have to do is try to sustain that. Dr Monteith: So, you talked about the importance of these global initiatives, which is huge, and other sectors outside of neurology. Like for example, technology, you spoke about telemedicine. I think you were referring to telemedicine with COVID. What other technologies that are more specific to the field of epilepsy, some of these monitorings that maybe can be done? Dr Clarke: I was just going to just going to jump on that. Thank you so much for asking. Dr Monteith: I have no disclosures in this field. I think it's important and exciting to think how can we increase access and even access to monitoring some of these technologies. That might be expensive, which is another issue, but…. Dr Clarke: So, the main things in epilepsy diagnosis and management: you want to hear from the patient history, you want to see what the seizures look like, and then you want to find ways in which to monitor those seizures. Hearing from the patient, they have these questionnaires that have been out there, and this is local, regional, global, many of them standardized in English and Spanish. Our colleagues in Boston actually created quite a neat one in English and Spanish that some people are using. Ecuador has one. We have created someone- something analogous. And those questionnaires can be sent out virtually and you can retrieve them. But sometimes seeing is believing. So, video uploads of seizures, especially the cell phone, I think has been management-changing for the field of epilepsy. The thing you have to do however, is do that in a HIPAA-compliant way. And several studies are ongoing. In my mind, one of the better studies here was done on the East Coast, but another similar study, to be unnamed, but again, written out in the articles. When you go into these apps, you can actually type in a history and upload a video, but the feed is not only going to you, it may be going to the primary care physician. So, it not only helps in one way in you educating the patient, but you educate that primary care physician and they become extenders and providers. I must add here my colleagues, because we can't do without them. Arguably in some instances, some of the most important persons to refer patients, that's the APPs, the PAs and the nurse practitioners out there, that help to refer patients and share patients with us. So, that's the video uploads they're seeing. But then the other really cool part that we're doing now is the ambulatory world of EEGs. Ceribell, Zeto, to name of few, in which you could potentially put the EEG leads on persons with or without the EEG technologist wirelessly and utilize the clouds to review the EEGs. It's not perfect just yet, but that person that has to travel eight hours away from me, if I could do that and negate that travel when they don't have money to pay for travel or they have some potential legal issues or insurance-related issues and I could read the EEG, discuss with them via telemedicine their care, it actually improves access significantly. I'm going to throw in one small twist that, again, it's not perfect. We're now trying to monitor via autonomic features, heart rate movement and others, for seizures and alert family members, parents, because although about 100,000 people may be affected with epilepsy, we're talking about 500,000 people who are also affected that are caregivers, affiliates, husbands, wives, etcetera. Just picture it: you have a child, let's say three, four years old and every time they have a seizure- or not every time, but 80% of times when they have a seizure, it alerts you via your watch or it alerts you in your room. It actually gives that child a sense of a bit more freedom. It empowers you to do something about it because you can understand here. It potentially negates significant morbidity. I won't stretch it to say SUDEP, but hopefully the time will come when actually it can prevent not only morbidity, but may prevent death. And I think that's the direction we are going in, to use technology to our benefit, but in a HIPAA-compliant way and in a judicious way in order to make sure that we not only don't overtreat, but at the end of the day, we have the patient as number one, meaning everything is vested towards that patient and do no harm. Dr Monteith: Great. One thing you had mentioned earlier was that there are even some simple approaches, efficiency approaches that we can use to try and optimize care for all in our clinics. Give me what I need to know, or do. Give me what I need to do. Dr Clarke: Yeah, I'll get personal as to what we're trying to do here, if you don't mind. The initial thing we did, we actually audited care and time to care delivery. And then we tried to figure out what we could do to improve that access and time to care, triaging, etcetera. A very, very simple thing that can be done, but you have to look at costs, is to have somebody that actually coordinates getting persons in and out of your center. If you are a neurologist that works in private practice, that could potentially be a nurse being associated directly one-and-one with one of the major centers, a third- or fourth-level center. That coordination is key. Educate your nurses about epilepsy care and what the urgent situations are because it will take away a lot of your headache and your midnight calls because they'll be able to know what to do during the day. Video uploads, as I suggested, regardless of the EMR that you have, figure out a way that a family could potentially send a video to you, because that has significantly helped in reducing investigative studies. Triaging appropriately for us to know what patients we can and cannot see. Extenders has helped me significantly, and that's where I'll end. So, as stated, they had many neurologists and epileptologists, and utilizing appropriately trained nurse practitioners or residents, engaging with them equally, and/or social workers and coordinators, are very helpful. So hopefully that's just some low-hanging fruit that can be done to improve that care. Dr Monteith: So why don't you give us some of your major takeaways to how we can improve epilepsy care for all people? Dr Clarke: I've alluded to some already, but I like counts of threes and fives. So, I think one major thing, which in my mind is a major takeaway, is cultural sensitivity. I don't think that can go too far in improving care of persons with epilepsy. The second thing is, if you see a patient that have tried to adequately use medications and they're still having seizures, please triage them. Please send them to a third- or fourth-level epilepsy center and demand that that third- or fourth-level epilepsy center communicate with you, because that patient will eventually come back and see you. The third thing---I said three---: listen to your patients. Because those patients will actually help and tell you what is needed. And I'm not only talking about listening to them medication-wise. I know we have time constraints, but if you can somehow address some of those social needs of the patients, that will also not only improve care, but negate the multiple calls that you may get from a patient. Dr Monteith: You mentioned a lot already. This is really wonderful. But what I really want to know is what you're most hopeful about. Dr Clarke: I have grandiose hopes, I'll tell you. I'll tell you that from the beginning. My hope is when we look at this in ten years and studies are done to look at equitable care, at least when it comes to race, ethnicity, insurance, we'll be able to minimize, if not end, inequitable care. Very similar to the intersectoral action plan in epilepsy by 2030. I'll tell you something that suggests, and I think it's global and definitely regional, the plan suggests that 90% of persons with epilepsy should know about their epilepsy, 80% of persons with epilepsy should be able to receive appropriate care, and 70% of persons with epilepsy should have adequately controlled epilepsy. 90, 80, 70. If we can get close to that, that would be a significant achievement in my mind. So, when I'm chilling out in my home country on a fishing boat, reading EEGs in ten years, if I can read that, that would have been an achievement that not necessarily I would have achieved, but at least hopefully I would have played a very small part in helping to achieve. That's what I think. Dr Monteith: Awesome. Dr Clarke: I appreciate you asking me that, because I've never said it like that before. In my own mind, it actually helped with clarity. Dr Monteith: I ask great questions. Dr Clarke: There you go. Dr Monteith: Thank you so much. I really- I really appreciate your passion for this area. And the work that you do it's really important, as you mentioned, on a regional, national, and certainly on a global level, important to our patients and even some very simple concepts that we may not always think about on a day-to-day basis. Dr Clarke: Oh, I appreciate it. And you know, I'm always open to ideas. So, if others, including listeners, have ideas, please don't hesitate in reaching out. Dr Monteith: I'm sure you're going to get some messages now. Dr Clarke: Awesome. Thank you so much. Dr Monteith: Thank you. I've been interviewing Dr Dave Clarke about his article on diversity and underserved patient populations in epilepsy, which appears in the most recent issue of Continuum on epilepsy. Be sure to check out Continuum Audio episodes from this and other issues. And thank you to our listeners for joining today. Dr Monteith: This is Dr Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use this link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.

Dave Clarke's Saga Series Episode 126

Dave Clarke's Saga Series Episode 125

This episode is all about hard techno: raw, relentless and packed with energy. In this 60-minute journey, I've pushed the boundaries of sound, weaving together pounding rhythms, fierce basslines, and an unapologetic intensity that defines the techno scene. You'll hear music from Sigvard, Cristian Glitch, Off Grid, Dave Clarke and many others. Tracklist 01 A.Morgan - Navigator 02 Flug - Psychopath (Cleric Remix) 03 Arnaud Le Texier - Reversal 04 Viels & Pyramidal Decode - Entropia Variabile 05 Michel Lauriola - Ephemeral Past 06 Sigvard - Isolation Tears 07 Introversion - Memories 08 Olexii - Fake Hill (Paul Birken Remix) 09 Hektor Legion - Echoes of Chaos 10 Cristian Glitch - Forbidden Desires 11 Norberto Lusso - Uytre 12 Off Grid - Renegades 13 Dave Clarke - Way of Life 14 Stef Mendesidis - The Dance Class 15 Sigvard - Echoes of Soltitude 16 Kobosil - Bei Nacht H (178) 17 MSKD - Entropy and Versatile https://www.facebook.com/lowfrequencypodcast https://www.facebook.com/itsmestevedj https://soundcloud.com/st-eve_dj

Dave Clarke's Saga Series Episode 124

The NBA Trade Deadline just shook up the league, and we're here to break it all down! Plus, we're diving deep into Super Bowl LVIII between the Kansas City Chiefs and Philadelphia Eagles—who has the edge, and what will decide the game?

Dave Clarke's Saga Series Episode 123

In this episode, Lyell K. Jones Jr, MD, FAAN, speaks with Jennifer L. Hopp, MD, FAAN, FAES, FACNS, who served as the guest editor of the Continuum® February 2025 Epilepsy issue. They provide a preview of the issue, which publishes on February 3, 2025. Dr. Jones is the editor-in-chief of Continuum: Lifelong Learning in Neurology® and is a professor of neurology at Mayo Clinic in Rochester, Minnesota. Dr. Hopp is a professor in the department of neurology at the University of Maryland School of Medicine in Baltimore, Maryland. Additional Resources Continuum website: ContinuumJournal.com Subscribe to Continuum: shop.lww.com/Continuum More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @LyellJ Guest: @JenHopp71 Full episode transcript available here Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum, the premier topic-based neurology, clinical review and CME journal from the American Academy of Neurology. Thank you for joining us on Continuum Audio, a companion podcast to the journal. Continuum Audio features conversations with the guest editors and authors of Continuum who are the leading experts in their fields. Subscribers to the Continuum Journal have access to exclusive audio content not featured on the podcast. If you're not already a subscriber, we encourage you to become one. For more information, please visit the link in the show notes Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum, Lifelong Learning in Neurology. Today I'm interviewing Dr Jennifer Hopp, who recently served as Continuum's guest editor for our latest issue on epilepsy. Dr Hopp is a professor and executive vice chair in the Department of Neurology at the University of Maryland School of Medicine, where she's also director of the Epilepsy Center. Dr Hopp, welcome. Thank you for joining us today. Why don't you introduce yourself to our listeners?  Dr Hopp: Hi, Dr Jones. Thank you so much for having me on this podcast. I really had so much fun working with you and other authors of this issue and serving as editor. I feel like it was yesterday that I was author of an article in the past. And so, it's really a pleasure to take on this new role and create the content for the issue of Continuum for Epilepsy and really particularly to work with the stellar group of experts and authors that we were able to have us join this year.  Dr Jones: I want to thank you for, really, it's a remarkable issue. And we usually don't get into this a lot with our guest editors, but our last issue on epilepsy came out in 2022. Fantastic issue, guest edited by Dr Natalie Jette. When you were designing the table of contents and article topics for this issue, you had some great ideas. Walk us through your thought process on what was most important to convey in this issue.  Dr Hopp: Sure, I'm happy to do so. I think one of the things about Continuum that is so accessible to everybody is that it really is, to me, preeminent format of updating and educating, whether it's epileptologist, neurologist, trainees in every area of epilepsy, which is obviously an enormous task to really pull together all of these data to make updates and then to make it accessible to all of these different levels of learners as well as people like myself. I really read and always look forward to all the Continuum issues outside of my field. I use it to update my knowledge base, get ready for boards. I also read it as an educator because I want to know what my trainees are reading during their rotations and I want to be able to share materials with them. So, I really tried to go back and look at other issues and think about how we could make it fresh. So, I think one of the first challenges is just making sure that we're updating the content of each article based on the literature and the data we have. That really becomes the task of the authors. And so first of all, selecting the authors was both fun but also really important to me. But the second aspect of it to me was really the question of, how could we make this fresh this year? I think Continuum is always fresh and that it has new data, but I wanted to really think outside the box and I appreciate being able to take a few risks. One of them was really headed by Dave Clarke, who provides this incredibly thoughtful and comprehensive review of access to care and epilepsy. I think for anyone who wants a primer on the issues and language used in discussions of diversity or social determinants of health---you first of all do not have to be in the field of epilepsy to read this. So, you should check that out. But I also thought it was really critical to shed more light on these issues. So, we tried to be mindful of this in threading that through as best as we could each article, but also have a stand-alone section that he headed. And so, he addresses issues of how to think about access to care for people with epilepsy, but actually, interestingly, also thinking about the investigators, providers, and researchers, and how we think about diversity in those viewpoints as well. I think we can always do better. Dave concludes with a wonderful focus on hope in this area with next steps for our community. So, I think that that was certainly one area that I wanted to take a risk and I think it was quite successful.  Dr Jones: Totally agree. I very much enjoyed that article. We have an article on implementation of guidelines and quality measures by Dr Christina Baca. I thought that was a great choice from your perspective, not only because Dr Baca is an expert on this, but it felt very practical, right?  Dr Hopp: Exactly. Exactly. And that was the other area that I thought really is always covered so well by the Academy of Neurology. There's so much work in updating the guidelines, whether it's the guideline that just was updated on people with epilepsy of childbearing potential or others outside of the field of epilepsy. And I thought that we could use Continuum to help educate all of the readers on how to take those guidelines and measures and then really bring them into practice. I think there's a whole field of implementation science that I think shines a light on the gap between the guidelines and the measures and then really what we do with them in practice. And that's actually what's most important for our patients and for the providers. And so Christine does just an amazing job as an expert, not only walking us through the guidelines that are relevant for epilepsy, but then helping us and providing, essentially, a toolkit to take those measures and guidelines and use them in a very feasible, accessible way in day-to-day practice. And I would suggest that it's relevant for anyone from a student level resident to an epileptologist who's been in practice, like me, for many years. And so I hope that's relatable and useful to the reader.  Dr Jones: I think it will be. And let's get right into it. So, I always enjoy talking to the guest editor. You're already an expert and now you've just read a bunch of articles and edited a bunch of articles from people who are really the premier experts in their area of the field, right? They're niche within epilepsy. So, as you've read these articles across the issue, if there were one biggest practice-changing recommendation that you would want to convey to our listeners, what would that be? Dr Hopp: I think that's a fabulous question because again, each of these articles, I think, is designed and written by the author to stand alone. But ideally, they need to all be incorporated in practice. And I think what each author was able to really successfully do is not only review the data, but really take us to the next level with practice of epilepsy. For example, I think as we embark on the next couple of decades, clearly increased technology, AI, personalized medicine are all buzzwords and taking the lead. In reality, with advances, we still have to make sure our care is personalized. And we have to remember seizures are really the symptom, but epilepsy is the disease. What I think our authors do well is make sure that our care is personalized to the patients. You could take that from the first article that Roohi Katyall writes about how to approach the patient with epilepsy, which is still, I think, the seminal way to start to think about these patients. But we need to ask issues pertaining to people with epilepsy of childbearing potential; screen for mood, other comorbidities. Mark Keezer does a great job talking about these. And then as we discussed, Christine Baca, PCU, talks about how to then incorporate those practical considerations into practice. Each author also, I think, emphasizes the need to utilize technology and testing and evaluation to make sure that our care is personalized for our patient. For example, we have a focus on certain special populations. Some patients who we see from the diagnosis of epilepsy end up not having seizures. They may have nonepileptic events. And so, Adriana Bermeo-Ovalle and her co-author talk about how to address those patients. Well, Meriem Bensalem-Owen talks about gender based issues in epilepsy as well. And, and that particular article also was updated and refreshed to really address gender and sex-based issues beyond treating the woman with epilepsy. So, I think in summary, each of them really helps us make sure that we're personalizing the care for patients by emphasizing a very thorough and individualized approach to each of our patients that we see with seizures.  Dr Jones: Now that you put it that way, that really did come across as a consistent theme essentially in every article, right? All the way from the evaluation of the patient suspected of having epilepsy to the treatment options to the context of care. Personalization is really kind of a continuous thread throughout the issue. So, I think that's a great one.  Dr Hopp: I think it's still aspirational in some sense, but hopefully practical in another. For example, we certainly are going to make a medication selection when we see each individual patient based on their comorbidities, perhaps genetic considerations, and how they may respond to medications or have risks of rash. But there are certainly still guidelines that we need to approach and think about when thinking about populations of people who have epilepsy as a whole. I think that what's interesting in the field of epilepsy is that we still don't have as much consensus as I think we could on the best way to treat, for example, a drug-resistant patient with epilepsy. One of, I think, the biggest areas of opportunity in terms of personalized medicine as we move forward is that there's such variability on patient care based on the epilepsy center, the tools that we have on how to treat these patients. And I think an aspiration is for us to, in the future, be able to see a patient who has seizures or a person who has seizures, maybe put an FDA-approved device, as Dan Friedman talks about in his article, to help detect the seizures. Use AI with EEG to detect abnormalities in their studies. And then use imaging processing and genetic or metabolic markers to really end up stratifying the risk and creating a treatment plan much akin to what's done in the world of cancer care. I think what's so exciting in epilepsy is that we have made so many advances in terms of our treatments, but I think there's so much to do to really stratify and personalize care for our patients that we really could take a lot of lessons from the world of cancer and in other fields of medicine to really be able to apply to our area of specialization.  Dr Jones: And I guess that's one of the common tensions in neurology---and medicine, really---is the pull between standardizing and protocolizing. And usually we do better when we're standardized in our care versus that personalization, doing the right thing for that individual person. And I guess expertise lies in the middle, which is why we want people to read these articles, right?  Dr Hopp: Exactly. I think you've hit the nail on the head, and I think the takeaway here is really that we need to do both. There's no question that we can't reinvent the wheel for every person who we see in the office who has epilepsy and not apply the knowledge that we've gained based on all of the research and work that's been done in the field of epilepsy. So, for example, we know that if someone is almost 25 years old, Quantum Brody published that shows that if someone does not respond to a few drugs, anti-seizure medicines, the likelihood that they're not going to respond, it is quite high. So, we need to apply data that we have to patients as a whole. But then, I think, what has changed and evolved over the past twenty-five years is our ability to potentially personalize some of that decision making. And that's where I think the field of epilepsy is right now, and hopefully where it's going to go in the next decade or so.  Dr Jones: So, what do you think the next big thing in epilepsy diagnosis or management will be? Dr Hopp: I think that technology is really going to play a role. Technology, I think, will take many forms. We hear a little bit about some of the new advances in technology in several articles in this issue. One, for example, is in the ability to manage even emergent seizures or clusters of seizures in patients. The ability to provide a nasal spray that works very quickly is so different than the tools that we had to treat seizures even 10 years ago. I think that technology will likely thread through many different areas of epilepsy care, whether it's in the treatment and availability of different medications or in the ascertainment of epilepsy itself. I think that one of the very exciting areas in technology is in pharmacogenomics and genetics, which hopefully will allow us to close the gap in selecting one of the better medications or best medication for a patient earlier in their diagnosis and in their treatment plan. If we are able to get patients treated more quickly, whether it's with medication or in selection of the best surgical treatment, hopefully we will close the gap in reducing the possibility of drug resistant epilepsy, but also have impact in quality of life and getting patients and people with epilepsy and doing that, doing the things that they want to do such as driving, going to work, getting engaged in the things that make them happy. And so, I think our ability to use technology, whether it's in using a watch to make a diagnosis of seizures or pharmacogenomics to make a good medication selection, hopefully this will allow us to speed up our algorithm in making a diagnosis and getting an effective treatment plan for patients earlier. And ultimately that's our goal. Our goal for patients is ideally to have no seizures and no side effects with a good quality of life.  Dr Jones: Yeah, the technology has really been breathtaking. You know, one of the commonalities between your practice and my practice is electrophysiology. I do neuromuscular electrophysiology, which is much simpler than what you do with cerebral electrophysiology. And whenever I sit down next to a colleague who is about to review forty-eight hours' worth of EEG recordings, I always think what a massive amount of data and I always feel sympathy for them. What, about AI? What about automated processing tools? Is that something that our listeners should look forward to in the future?  Dr Hopp: I think so. And I hope it's a blend. I hope that---and I always actually talk about this with trainees because I love EEG so much and I love translating the principles of physics and neurophysiology when we're sitting in front of an EEG with our trainees. I am excited about AI and technology. I will admit that I hope that it doesn't replace human readers because I do think that there is an importance in threading history and semiology and thoughtfulness in a human way with the interpretation of EEG. However, you're absolutely right that the amount of data is just becoming overwhelming for epileptologists and for EEG-ers to be able to synthesize in a reasonable and feasible amount of time. So, we already are seeing the applicability of the AI to, for example, prescreen large, large amounts of EEG data and try to at least give us tools for the ability to screen EEG in a more efficient way. I think some of the more exciting areas of EEG that are coming are in the background, which is in the network analysis in high-density EEG. There are very, very smart mathematicians that currently I'm collaborating with in utilizing network analysis of EEG that will hopefully allow us to apply these algorithms to EEGs that even look normal to the naked eye, but actually may have signals that help us predict who may or may not have seizures. I agree with you wholeheartedly. I think there's so much to come and our collaboration and integration with engineers and mathematicians, I think, is going to be paramount. Dr Jones: Dr Hopp, what was your path to epilepsy?  Dr Hopp: Dr Jones, that is a great question. It was not linear and it really evolved over time, but basically went something like this. I majored in behavioral biology in college, and I was fascinated by the brain and how behavior was controlled by either physiology or anatomy or abnormalities in brain function. And as I moved along in my career and education, I really had a passion for neurology and for behavioral science. But I went to medical school and absolutely loved most of the rotations I did. And in fact, I loved OBGYN so much that I changed my entire career path with the goal of becoming an OBGYN and delivering babies. And I was really torn between two specialties of going into neurology or OB. And I went to a very sage advisor, Greg Kane up at Jefferson. And I said, I really don't know what field to go into. I love aspects of both. I like doing testing. I like making immediate impact. But I also love neurology. And he gave me some of the best advice, I think, that I have ever heard. And I try to share with our trainees all the time. He said, Jenny, I think you'll be successful at either, but which do you like reading about? And I had a relative epiphany at the time, and it was no question that I loved reading about neurology. It was very clear to me that reading about neurology and learning about the brain was just fascinating and led me to do a neurology residency where I was exposed to patients with epilepsy. And it really just continued to pique my interest to read about a field that I felt I could have such an impact. I really could help patients make a diagnosis relatively quickly and have a significant impact, maybe as I would in OBGYN but in a little bit different way. And it really has been, to me, the best choice that I could have made. And on a day-to-day basis, I still love reading about neurology. So, it was some of the best advice that I was given and I try to share that with others. Dr Jones: What a great question for a mentor to ask. And I wonder if he was really thinking, if she likes to read, she probably should be a neurologist to begin with. You like to read, don't we?  Dr Hopp: I think so. I think he was spot on. I think he knew the answer before he asked the question.   Dr Jones: Dr Hopp, thank you for joining us today. Thank you for such a thorough and fantastic discussion on caring for patients with epilepsy and our recent issue on epilepsy for Continuum. Dr Hopp: My pleasure. Thank you for having me. Dr Jones: Again, we've been speaking with Dr Jennifer Hopp, guest editor of Continuum 's most recent issue on epilepsy. Please check it out. And thank you to our listeners for joining today. Dr Monteith: This is Dr Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use this link in the episode notes to learn more and subscribe. Thank you for listening to Continuum Audio.

Dave Clarke's Saga Series Episode 122

Dave Clarke's Saga Series Episode 121

Dave Clarke's Saga Series Episode 120

Dave Clarke's Saga Series Episode 119

This week on Missing the Point, Dave Clarke and Rayshawn Buchanan dive headfirst into the hottest topics shaping the NFL as Week 14 closes and Week 15 looms. The episode kicks off with a bombshell as the duo unpacks Bill Belichick's stunning decision to leave the NFL for UNC, dissecting its seismic implications for his legacy and the league at large. With their signature blend of humor and unfiltered insight, they tackle the week's power rankings, pitting the Lions' meteoric rise against the Chiefs' grit. From bold playoff predictions to the teams who've officially crossed the postseason finish line in defeat, this episode is packed with sharp analysis and bold takes. They also dive into draft scenarios for struggling teams like the Patriots and Cowboys, pondering what it takes to rebuild. With an electric vibe that fuses NFL analysis with hip-hop culture, this episode is a must-listen for fans looking for authentic and engaging commentary. Key Topics: Bill Belichick shocks the NFL by heading to UNC: What's next for his legacy? Lions on fire: Can Detroit secure their place at the top? Teams officially eliminated: What went wrong? Cowboys' embarrassing loss and the Patriots' high-stakes draft decisions Playoff hopefuls: Texans, Dolphins, and others fighting for a spot Predictions for Week 15's biggest matchups Explore more on our website: https://www.MTPshow.com Connect with us on social media: https://linktr.ee/MTPSHOW Meet our hosts: Mike Marcangelo Dave Clarke Rayshawn Buchanan Bob Kelly Produced by Craig D'Alessandro For inquiries, contact Craig at Craig@mtpshow.com Learn more about your ad choices. Visit megaphone.fm/adchoices

Get ready for a deep dive into the biggest NFL headlines and power rankings as we head into Week 14 of the 2024 season! In this episode of Missing the Point, Dave Clarke, Bob Kelly, Rayshawn Buchanan, and Mike Marcangelo analyze the top teams in the league, discuss playoff implications, and debate the future of struggling franchises. From the Lions' incredible season and the Chiefs' dominance to the Bills' resurgence and the Ravens' playoff ceiling, we leave no stone unturned. We also react to the shocking firing of Bears coach Matt Eberflus and the aftermath of Azeez Al-Shaair's controversial hit on Trevor Lawrence. Can the Chargers salvage their season under Harbaugh? Are the Steelers serious contenders in the AFC? Plus, we cross off teams like the Patriots, Cowboys, and Giants from playoff contention and evaluate dark-horse candidates like the Texans, Seahawks, and Packers. Whether you're rooting for the Lions to continue their Cinderella season or wondering what's next for your favorite team, this episode delivers all the insights and laughs you need for your NFL fix. Don't miss this passionate, opinionated, and fun discussion on the current state of the league! Chapters & Timestamps: 0:00

In this jam-packed episode of Missing the Point, Dave Clarke and Mike Marcangelo break down all the action as we dive into Week 13 of the NFL season. This week, the shocking release of Daniel Jones by the New York Giants takes center stage. The hosts dissect the franchise's controversial decision, debating whether this signals a much-needed rebuild or yet another misstep for a team that hasn't found its footing in years. What does this move mean for the Giants' draft strategy? And could they secure the No. 1 overall pick in a year with limited quarterback options? The conversation transitions seamlessly into the updated power rankings. Dave and Mike spotlight the league's top contenders and underdog surprises. Are the Eagles cementing their place as the NFC's best hope for a Super Bowl win? Can the Lions continue their historic playoff push and bring a championship to Detroit? The Broncos' resurgence under Sean Payton gets attention as the team mounts an unlikely comeback after a rocky start to the season. The NFC South's chaos also takes the spotlight, with a heated debate over whether the Saints or Falcons can emerge from a wildly inconsistent division. Who has the edge in this unpredictable race, and what does it mean for their playoff chances? As always, the episode features passionate rants and debates. Dave calls out the Bears' coaching staff for hindering Caleb Williams' development, while Mike takes a hard look at the Patriots' ongoing struggles and the future of current head coach Jerod Mayo and where the future of Bill Belichick might lie in the NFL if he chooses to return. The duo wraps up with bold playoff predictions, analyzing whether teams like the Dolphins, Rams, and even the Cardinals have what it takes to make a deep postseason run. From team analysis and rankings to hot takes and playoff implications, this episode is a must-listen for fans who want to stay ahead of the game as the NFL season reaches its most critical point. Noteworthy Timestamps: 0:00 – Intro & Week 13 Overview: What's at Stake? 2:00 – Giants Release Daniel Jones: Rebuild or Regression? 10:00 – Cross-Off Teams: Jaguars, Panthers, Browns & More 20:00 – Power Rankings Highlights: Eagles, Lions & Broncos Climbing 35:00 – NFC South Showdown: Saints vs. Falcons for Division Lead 45:00 – Bears' Coaching Crisis: Caleb Williams' Future at Risk 55:00 – Where might Bill Belichick Coach next season? 1:05:00 – Playoff Sleepers: Can Dolphins, Rams, or Cardinals Make Noise? ------------------ Explore more on our website: https://www.MTPshow.com Connect with us on social media: https://linktr.ee/MTPSHOW Meet our hosts: Mike Marcangelo Dave Clarke Rayshawn Buchanan Bob Kelly Produced by Craig D'Alessandro For inquiries, contact Craig at Craig@mtpshow.com Learn more about your ad choices. Visit megaphone.fm/adchoices

In this week's episode of Missing the Point, hosts Dave Clarke and guest Matt Wilcox from Check My Oil dive into the biggest stories shaping Week 12 of the NFL season. They start with the fallout in New York, where the Jets are making headlines with sweeping organizational changes. GM Joe Douglas is out, and the future of Aaron Rodgers is hanging in the balance. Dave and Matt debate whether Rodgers' career is defined by brilliance or disappointment, dissecting his legacy in Green Bay and his brief tenure with the Jets. How does he stack up against legendary quarterbacks like Tom Brady, Peyton Manning, and Drew Brees? The hosts shift to this week's power rankings, highlighting cross-off teams and surprise playoff contenders. They break down the struggles of teams like the Jaguars, Browns, and Panthers, questioning whether they're officially out of playoff contention. On the flip side, they spotlight the rise of the Vikings, 49ers, and Cardinals, analyzing their playoff potential and the keys to their recent success. As the NFC South continues to baffle fans, the duo tackles the chaos in the division. Can the Saints separate themselves in a group led by inconsistent quarterbacks like Baker Mayfield and Derek Carr? Will the Bucs or Falcons mount a comeback to take the lead? Dave and Matt provide deep insights into one of the most unpredictable divisions in the NFL. Finally, the conversation turns to broader league storylines, including the Chicago Bears' ongoing rebuild and the bright future of quarterback prospect Caleb Williams. Matt shares a passionate critique of the Bears' coaching staff and leadership, questioning whether a coaching overhaul is the key to unlocking their potential. With bold predictions, detailed analysis, and spirited debates, this episode has something for every NFL fan looking to stay on top of the season's biggest storylines. Noteworthy Timestamps: 0:00 – Introduction & Welcome to Guest Host Matt Wilcox 2:00 – Jets Shake-Up: Joe Douglas Out, Rodgers' Future in Limbo 10:00 – Aaron Rodgers Legacy Debate: Brilliance or Overhyped Career? 15:00 – Week 11 Cross-Off Teams: Jaguars, Browns, Panthers & Others 25:00 – NFC South Chaos: Can Saints Dominate an Unpredictable Division? 35:00 – Power Rankings Spotlight: 49ers, Cardinals, and Vikings Rising 50:00 – League-Wide Concerns: Bears Rebuild, Caleb Williams & Coaching Woes 1:10:00 – Closing Thoughts & Week 11 Playoff Picture Predictions ------------------ Explore more on our website: https://www.MTPshow.com Connect with us on social media: https://linktr.ee/MTPSHOW Meet our hosts: Mike Marcangelo Dave Clarke Rayshawn Buchanan Bob Kelly Produced by Craig D'Alessandro For inquiries, contact Craig at Craig@mtpshow.com Learn more about your ad choices. Visit megaphone.fm/adchoices

This week, host Dave Clarke, Bob Kelly, and Rayshawn Buchanan dive into the latest on NFL Week 11 power rankings, spotlighting the rising contenders and struggling teams as playoff hopes hang. The episode starts with Dave's intense “State of the Sizzle” segment, where he covers the ongoing drama with the Chicago Bears, who recently fired offensive coordinator Shane Waldron. With interim OC Thomas Brown stepping in, will the Bears finally find their footing, or is it time to brace for a tough season end? The hosts share their takes on the coaching shake-ups and discuss what these changes mean for Chicago's future. Next, they shift to cross-off teams, debating if it's time to call it quits on the Giants, Cowboys, and Jets. Are these teams officially out of playoff contention, or could there be a chance for an unexpected comeback? The hosts assess each team's challenges and potential for a late-season turnaround. Dave, Bob, and Rayshawn go deep into the Week 11 power rankings in the episode's heart, focusing on the 49ers, Cardinals, and Vikings. Are the 49ers still a contender despite recent setbacks? Could the Cardinals become a surprise playoff threat? And is the Vikings' impressive 7-2 record sustainable in the long run? As they discuss each team's strengths and weaknesses, they also look at the upcoming Eagles-Commanders matchup, debating if Washington has what it takes to pull off an upset against a top NFC team. Finally, they address growing player health concerns, particularly for quarterbacks, spotlighting Tua Tagovailoa's risky season with the Dolphins and the broader mental and physical toll on players. With everything from predictions to heated debates, this episode is packed with insights on the biggest Week 11 storylines! Noteworthy Timestamps: 0:00 – Dave Returns & “State of the Sizzle” on Bears' Coaching Crisis 2:00 – Bears Fire OC Shane Waldron: Season Impact & Coaching Changes 8:00 – Cross-Off Teams: Giants, Cowboys, and Jets Out of Playoffs? 15:00 – Week 11 Power Rankings Analysis: 49ers' Comeback Potential & Cardinals' Rise 28:00 – Are the Vikings at 7-2 True Playoff Contenders? 40:00 – Eagles vs. Commanders Preview: Can Washington Deliver an Upset? 50:00 – Player Health Debate: Brain Injuries, Tua's Season, and NFL Safety Risks 1:00:00 – Wrap-Up & Final Thoughts on Week 11 Power Rankings and Playoff Hopes ------------------ Explore more on our website: https://www.MTPshow.com Connect with us on social media: https://linktr.ee/MTPSHOW Meet our hosts: Mike Marcangelo Dave Clarke Rayshawn Buchanan Bob Kelly Produced by Craig D'Alessandro For inquiries, contact Craig at Craig@mtpshow.com Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of Missing the Point, hosts Mike Marcangelo, Dave Clarke, and Rayshawn Buchanan bring a fiery discussion on the biggest storylines from both the NBA and NFL in Week 10. Kicking things off, the trio dives deep into the Boston Celtics' recent games, analyzing the intense matchups, especially their nail-biting showdown against the Golden State Warriors at home. The hosts reflect on the atmosphere at TD Garden and break down how new additions like Buddy Heald and Kyle Anderson are elevating the Warriors' bench, making them a real threat in the West. They also examine how Jayson Tatum's game has reached MVP caliber, noting his growth as a leader on the court and how his scoring, rebounding, and playmaking skills have solidified his standing as one of the league's best. Switching gears, the hosts delve into the brewing rivalry between the Celtics and the Milwaukee Bucks. With Giannis Antetokounmpo's heated exchanges with Celtics players, this matchup has become one of the NBA's most intense. Is Giannis getting frustrated with Milwaukee's struggles? The hosts question if the Bucks are in decline after their rough start, dissecting roster issues and whether Coach Doc Rivers can survive the season if Milwaukee can't turn it around. In the second half, Dave delivers an impassioned “State of the Sizzle” segment, an open letter to the Chicago Bears' ownership calling for drastic change. Dave's plea to the McCaskey family to sell the team strikes a chord with frustrated Bears fans as he details the lack of leadership, mismanagement, and issues that have plagued Chicago's franchise for decades. The group then pivots to the Patriots' dominant 19-3 victory over the Bears, debating if this win signifies real progress for New England or is just another example of Chicago's collapse. With a new coaching approach in New England, Mike, Dave, and Rayshawn break down how the Patriots leverage their talent and defensive strategy for a stronger season finish. This episode covers everything from MVP talks and franchise futures to major NFL takeaways, leaving listeners with plenty to think about as the NBA and NFL seasons intensify. Noteworthy Timestamps: 0:00 – Celtics-Warriors Recap: Big Takeaways & Atmosphere at TD Garden 5:00 – Jayson Tatum's MVP Case: Celtics' Core Growth & Potential Weaknesses 10:00 – Celtics vs. Bucks Rivalry: Giannis's Heated Antics & Roster Challenges 20:00 – Milwaukee's Coaching and Roster Issues Under Scrutiny 28:00 – “State of the Sizzle”: Dave's Powerful Open Letter to Bears Ownership 40:00 – Patriots vs. Bears Analysis: Was It New England's Best Game Yet? 50:00 – Breaking Down Patriots' Defensive Coaching & Schemes 1:00:00 – Wrapping Up with NBA and NFL Insights & Season Outlooks ------------------ Explore more on our website: https://www.MTPshow.com Connect with us on social media: https://linktr.ee/MTPSHOW Meet our hosts: Mike Marcangelo Dave Clarke Rayshawn Buchanan Bob Kelly Produced by Craig D'Alessandro For inquiries, contact Craig at Craig@mtpshow.com Learn more about your ad choices. Visit megaphone.fm/adchoices

In this episode of Missing the Point, hosts Dave Clarke, Rayshawn Buchanan, and Bob Kelly dive into the NFL Week 9 power rankings and key storylines shaping the season. The show opens with the highly anticipated power rankings, with a focus on the recent rise of the Ravens and Steelers in the AFC North and the continued dominance of top-tier teams like the 49ers and Chiefs. The hosts also discuss the Patriots' recent win and how QB Drake Maye's concussion against the Jets could impact their game against the Titans. Will Jacoby Brissett have another strong outing, or will Maye return to lead the Pats? The hosts continue with their analysis of the “cross-off teams,” examining which franchises, like the Saints, Giants, and Vikings, are looking at a season beyond repair. The Colts' quarterback change to Joe Flacco stirs up a lively debate—will Flacco bring stability or prove to be a short-term fix? Wrapping up, Dave, Rayshawn, and Bob make bold predictions for Week 9 matchups, highlighting teams like the Eagles, Lions, and Rams as playoff contenders. Tune in for engaging takes, weekly predictions, and in-depth NFL analysis on which teams have what it takes to go the distance in 2024! Timestamp Chapters: 0:00 - Introduction & NFL Week 9 Power Rankings Breakdown 5:00 - Patriots Win, Drake Maye's Concussion & QB Situation 12:00 - Cross-Off Teams: Saints, Giants, Vikings & More 28:00 - AFC North Standouts: Ravens & Steelers Rising 35:00 - Joe Flacco Takes Over Colts Offense: Impact & Outlook 47:00 - Week 9 NFL Picks: Key Matchups and Predictions 59:00 - Final Thoughts: Contenders, Playoffs & NFL Surprises ------------------ Explore more on our website: https://www.MTPshow.com Connect with us on social media: https://linktr.ee/MTPSHOW Meet our hosts: Mike Marcangelo Dave Clarke Rayshawn Buchanan Bob Kelly Produced by Craig D'Alessandro For inquiries, contact Craig at Craig@mtpshow.com Learn more about your ad choices. Visit megaphone.fm/adchoices

In this week's episode of Missing the Point, hosts Dave Clarke, Rayshawn Buchanan, and Bob Kelly dive into an action-packed discussion covering the Celtics' season start and the latest NFL news. They kick off by celebrating the Celtics' powerful 4-0 run, emphasizing Jayson Tatum and Jaylen Brown's impressive performances. The team breaks down Joe Mazzulla's impact on ball movement, Payton Pritchard's development, and key wins over Eastern Conference rivals. Could this early success signal a championship year for Boston? The conversation then shifts to the New England Patriots, fresh off a win but still grappling with uncertainty at quarterback after rookie Drake Maye's concussion. With Jacoby Brissett stepping in, the hosts explore the team's offensive strategy, potential rebuilding options, and what Jerod Mayo's future could hold if the team can't find its footing. They wrap up with NFL Week 8 predictions, offering insights into the most anticipated matchups and which teams might surprise fans with an unexpected playoff push. Join us for in-depth Celtics analysis and all the NFL insights you need this week! Timestamp Chapters: 0:00 - Introduction & Celtics' Hot 4-0 Start 1:05 - Tatum & Brown's Standout Performances 5:00 - Celtics' Defense & Pritchard's Growth 10:38 - Contenders in the Eastern Conference 24:46 - Patriots' Win & Drake Maye's Concussion 42:13 - Jacoby Brissett's Role & Offensive Improvements 47:02 - NFL Week 8 Matchups & Key Predictions 55:00 - Final Thoughts: Celtics & NFL Playoff Contenders ------------------ Explore more on our website: https://www.MTPshow.com Connect with us on social media: https://linktr.ee/MTPSHOW Meet our hosts: Mike Marcangelo Dave Clarke Rayshawn Buchanan Bob Kelly Produced by Craig D'Alessandro For inquiries, contact Craig at Craig@mtpshow.com Learn more about your ad choices. Visit megaphone.fm/adchoices