Podcasts about coenzyme q10 coq10

This is a high energy conversation with renowned preventative cardiologist Dr Ross Walker and fx Medicine by BioCeuticals ambassador Dr Michelle Woolhouse. Dr Walker makes the specialist field of preventative cardiology accessible; he does this through his use of insightful explanations and well-crafted analogies from his 45 years of practice. Coenzyme Q10 (CoQ10) and its active form ubiquinol, take centre stage in this discussion, including Dr Ross Walker's use of ubiquinol in cardiovascular disease (CVD), how ubiquinol can be used to reduce the side effects associated with statins, and the research showing CoQ10/ubiquinol to decrease all-cause mortality. Dr Walker talks much more than just ubiquinol, including the importance of measuring calcium coronary artery score in assessing cardiovascular risk, his well-tested protocol for lipoprotein (a), diabobesity and the impact of insulin resistance, and his not to be missed five keys of being healthy. There are practice pearls a plenty: when statins are necessary, the importance of lifestyle and diet interventions for heart health, and the real pandemic of our time; diabobesity. Find today's transcript and show notes here: https://www.bioceuticals.com.au/education/podcasts/ubiquinol-s-role-in-preventative-cardiology-with-dr-michelle-woolhouse-and-dr-ross-walker Sign up for our monthly newsletter for the latest exclusive clinical tools, articles, and infographics: https://pages.blackmores.com.au/FXM-signup.html ***DISCLAIMER: The information provided on fx Medicine by BioCeuticals is for educational and informational purposes only. The information provided is not, nor is it intended to be, a substitute for professional advice or care. Please seek the advice of a qualified health care professional in the event something you learn here raises questions or concerns regarding your health.***

In this episode, Dr. Craig Koniver, M.D., a board-certified physician trained at Brown University and Thomas Jefferson University, discusses the therapeutic application of peptides and hormones for enhancing physical and mental health and performance. We explore GLP-1 analogs for weight loss, BPC-157 for wound healing and reducing inflammation, as well as peptides that increase growth hormone, improve REM sleep, and enhance cognitive function. We also cover testosterone therapy, NAD, NMN, and NR supplementation, methylene blue for mitochondrial health, stem cell therapies, and supplements such as CoEnzyme Q10 and methylated B vitamins. Additionally, we discuss effective dosages, sourcing, safety considerations, and the importance of working with knowledgeable physicians. Whether you're currently using peptides or exogenous hormones, or simply curious about their potential benefits and risks, this episode provides the scientific rationale behind how peptides function, their potential to enhance mental and physical health, and how they can optimize performance. Access the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Joovv: https://joovv.com/huberman BetterHelp: https://betterhelp.com/huberman Function: https://functionhealth.com/huberman Eight Sleep: https://eightsleep.com/huberman Timestamps 00:00:00 Dr. Craig Koniver 00:04:52 Sponsors: Joovv & BetterHelp 00:07:40 What is a Peptide? 00:09:37 GLP-1 Agonists, Semaglutide Weight Loss, Brain Health 00:15:49 GLP-1 Microdoses, Muscle Loss; Inflammation 00:18:43 BPC-157, Inflammation 00:23:27 BPC-157, Injection & Oral Forms; Injury Repair 00:28:43 Sourcing, Anabolic Steroids, Testosterone 00:34:48 Black & Gray Market, Compounding Pharmacies, Purity 00:38:20 Sponsor: AG1 00:39:51 Partnering with a Physician, LPS 00:43:00 BPC-157, Pentadeca Arginate (PDA); Side Effects & Doses 00:46:35 Ipamorelin, GHRP-6, Sleep, Appetite; Tool: Sleep & Growth Hormone 00:54:17 Tesamorelin, Sermorelin, CJC-1295; Stacking Peptides 00:58:45 Sponsor: Function & Eight Sleep 01:01:54 Coenzyme Q10 (CoQ10), Mitochondrial Health 01:05:16 Prescriptions, Physicians & Trust 01:14:09 Agency in Your Health 01:17:13 MK-677, Appetite 01:19:32 Hexarelin; Growth Hormone Secretagogues Dosing 01:21:10 Methylated B Vitamins, Homocysteine 01:24:47 Peptides for Sleep, Pinealon, Epitalon 01:31:03 Glycine, Liver Detoxification; Dosage 01:37:19 GLP-1, Compounding Pharmacies 01:39:03 Stem Cell Therapy, PRP 01:41:18 Thymosin Alpha-1, Cerebrolysin & Brain Health 01:44:17 Peptides for Cognitive Function, Methylene Blue, Doses 01:50:20 Covid, NAD Infusion, NMN & NR Supplements 01:57:13 Nutritional Deficiencies; NAD Dose & Regimen, NMN & NR 02:07:53 PT-141, Vyleesi, Libido; Nausea 02:10:57 FDA Approval & Removal, Pharmaceutical Companies 02:20:17 Positivity, Mindset & Health 02:26:23 Zero-Cost Support, YouTube, Spotify & Apple Follow & Reviews, Sponsors, YouTube Feedback, Protocols Book, Social Media, Neural Network Newsletter Disclaimer & Disclosures

In this episode (video here on YouTube), we explore the potential of Coenzyme Q10 (CoQ10), also known as Ubiquinone, in the treatment of Parkinson's disease symptoms.  CoQ10, a naturally occurring compound found in every cell of the body, plays a crucial role in mitochondrial function and energy production. Research suggests that individuals with Parkinson's disease may have lower levels of CoQ10 in their brains, potentially contributing to mitochondrial dysfunction and oxidative stress.  By supplementing with CoQ10, individuals may be able to bolster mitochondrial function, enhance cellular energy production, and reduce oxidative damage—all of which are key factors in the progression of Parkinson's disease. While more research is needed to fully understand the role of CoQ10 in treating Parkinson's disease, the current evidence is encouraging. Join us as we delve into the science behind CoQ10 and its potential to offer hope to those living with Parkinson's disease. Subscribe to our channel for more informative content on health, wellness, and the latest research on Parkinson's Disease. Start here on Amazon to find supplemental CoQ10. This one is the best rated on Amazon and has a 4 month supply! https://amzn.to/4bnDER3 Join this channel to get access to member's only content and perks: https://www.youtube.com/channel/UC0g3abv8hkaqZbGD8y1dfYQ/join  https://www.patreon.com/pdeducation Medical Disclaimer All information, content, and material of this video is for informational purposes only and not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified physician or healthcare provider. Affiliate disclaimer: Keep in mind that links used for recommended products may earn me a commission when you make purchases. However, this does not impact what products I recommend. If I recommend a specific product it is because it has been vetted by myself or based on personal use #parkinson #parkinsonsawareness #parkinsonsdisease #parkinsons #supplements #coq10 #mitochondria #oxidativestress #antioxidants

Coenzyme Q10 (CoQ10) is a powerful antioxidant made within the body. However, there are a number of circumstances that interfere with its production, leaving the body vulnerable to severe free radical damage. Listen in this week as Dee discusses the role of CoQ10, the conditions that may  benefit from increased amounts of CoQ10, and the best food sources and forms of supplemental CoQ10.Link to CoQ10: https://amzn.to/3nE3vwM

Return podcast guest and Designs for Health Chief Science Officer Dr. Barrie Tan is back on the Conversations for Health podcast for a continuation of our conversation about Vitamin E and  Coenzyme Q10 (CoQ10). Together we discuss Dr. Tan's invention of the combined CoQ10 and GG compound, key differences and similarities of ubiquinone and ubiquinol, and CoQ10 as a memory retention and agent that can counteract adverse effects of statin medications. Dr. Tan details his discovery of the benefits of the annatto plant and highlights the encouraging research findings regarding tocotrienol use in neurological health for those who are dedicated to improving the aging process.  I'm your host, Evelyne Lambrecht, thank you for designing a well world with us. Key Takeaways: [2:32] Dr. Barrie Tan details his invention of the combined CoQ10 and GG compound. [5:13] Key differences and similarities of ubiquinone and ubiquinol. [10:26] The dual benefits of both taking and making ubiquinol with GG to address a mitochondrial dysfunction energy deficit as we age. [12:23] Identifying the functioning location of CoQ10 in particular cells. [16:58] Dr. Tan explains his GG and CoQ10 recommendations for statin users. [27:27] Dosing ranges for GG based on age, MK-4 levels, and other health concerns. [33:23] Future research possibilities on compound GG include body fat, energy transfers, and body temperature regulation. [38:36] Addressing concerns regarding tocopherols that are commonly found in food. [41:35] The environmental impact of sourcing annatto plants. [45:03] Dr. Tan reflects on his experience of finding the annatto plant. [48:56] Research findings regarding tocotrienol use in neurological health. Episode Resources: Dr. Barrie Tan    The Truth About Vitamin E: The Secret to Thriving with Annatto Tocotrienols Design for Health Resources: Designs for Health Tocotrienols White Paper Blog: Combination of Geranylgeraniol + Ubiquinol to Support Mitochondrial Function Blog: CoQ10 Helps Promote Mitochondrial Function Blog: Bisphosphonates and Bone Health: Is There a Role for Geranylgeraniol? Blog: Vitamin E Tocotrienols, Metabolic Health, and Healthy Aging Webinar: Lipid-Soluble Nutrients in Metabolic Syndrome: The Supportive Roles of Tocotrienols, Resveratrol, and Vitamin D Presentation: Dr. Barrie Tan at CASI 2022: Annatto Tocotrienol & Geranylgeraniol Visit the Designs for Health Research and Education Library which houses medical journals, protocols, webinars, and our blog.

Prospects Of Anti-Aging Supplements For 2023 And Beyond Click Here for a FREE 15 min Zoom Consultation With Brad: Dr. Michael Turner - Integrative Medicine Physician www.drturner.substack.com In this podcast episode, host Brad Williams from Over 40 Fitness Hacks interviews Dr. Michael Turner, an Integrative Medicine expert, on the topic of anti-aging supplements in 2023. Dr. Turner begins by explaining the importance of understanding the physiological factors driving the aging process. He introduces the concept of telomeres, which are protective caps on the end of DNA strands. Telomeres naturally shorten with each cell division, eventually causing cells to stop dividing. Dr. Turner then highlights an anti-aging supplement called "Gotu Kola," which has the ability to modify telomere length and help maintain their integrity. This supplement is particularly beneficial for promoting longevity. The conversation shifts to mitochondrial health, emphasizing the significance of well-functioning mitochondria as the powerhouses of cells. Dr. Turner mentions high-intensity exercise as a key strategy to optimize mitochondrial health. Additionally, he discusses the role of Coenzyme Q10 (CoQ10) as a supplement that enhances mitochondrial function, boosts energy production throughout the body, and serves as an antioxidant. He also notes that CoQ10 can benefit various organ systems and individuals with conditions like chronic fatigue and fibromyalgia. The podcast then delves into the importance of DNA repair in the context of aging and cancer risk. Dr. Turner explains that DNA constantly sustains damage and relies on repair mechanisms to prevent cancerous growth. FOXO genes play a crucial role in promoting DNA repair, and he outlines lifestyle practices like intermittent fasting to stimulate their activity. Dr. Turner introduces EGCG (epigallocatechin gallate), a component found in green tea, as a supplement that directly stimulates FOXO gene activity, thus supporting DNA repair. Brad shares his experience with matcha green tea and EGCG supplementation, noting that EGCG supplements can be a convenient alternative for individuals who experience digestive discomfort with green tea. Overall, the podcast provides valuable insights into anti-aging supplements, telomere maintenance, mitochondrial health, and DNA repair, offering listeners practical information to support their holistic approach to longevity and well-being in 2023. If you're interested in online personal training or being a guest on my podcast, "Over 40 Fitness Hacks," you can reach me at projectb36@gmail.com or visit my website at: www.Over40FitnessHacks.com Additionally, check out my Yelp reviews for my local business, Evolve Gym in Huntington Beach, at https://bit.ly/3GCKRzV

A new study entitled, “Coenzyme Q10 + alpha lipoic acid for chronic COVID syndrome” has been published in the journal Clinical and Experimental Medicine which found that supplementation with Coenzyme Q10 (CoQ10) and alpha lipoic acid (ALA) may be helpful in Long COVID. COVID-19 can deplete CoQ10 levels and damage the mitochondria which are important for energy production and immune system function. CoQ10 and alpha lipoic acid can both be helpful in protecting and supporting mitochondrial function by reducing oxidative stress. CoQ10 deficiency can lead to decreased energy production resulting in fatigue and increased free radical production. Fatigue is by far the most common symptom reported in Long COVID so CoQ10 is at the top of the list of supplements to try with this condition. Alpha lipoic acid is a powerful antioxidant, and it is involved in mitochondrial energy production. ALA also has immunomodulatory properties and may actually be an anti-viral as well. The properties of both nutrients in theory make them a promising combination in the treatment of Long COVID. How was the study done? 174 patients (51% male and 49% female) aged 18-81 (mean of 51) who had COVID-19 previously and met the 2015 National Academy of Medicine diagnostic criteria of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). 52% had comorbidities including chronic lung disease (16%, 28/174), diabetes mellitus (13%,23/174), psychiatric diseases (7.5%, 13/174), and rheumatic diseases (9.8%, 17/174). 17.8% (31) of patients had been previously hospitalized for severe respiratory SARS-CoV-2 pneumonia. 82.2% had mild/moderate symptoms during the acute phase. The mean duration of Long COVID symptoms was 5.9 months. The most common symptoms were fatigue (80%), impaired concentration (68%), sleep disorders (85%) disturbed smell and/or taste (60%), memory loss (45%), dyspnea (21%) and arthromyalgias (64%). Patients were divided into two groups. The first one (116 patients) received coenzyme Q10 (ubiquinone form) and alpha lipoic acid taken every day for two months at a dose of 100 mg of CoQ10 and 100 mg of alpha lipoic acid twice a day. The control group of 58 patients did not take either supplement. The characteristics of the patients in the two groups were similar at baseline. Patients in both groups also received a variety of medications including paracetamol, codeine, NSAIDS, antidepressants (duloxetine), anticonvulsants and analgesics (pregabalin and gabapentin). They also undertook psychological and psychiatric counseling, physio-kinesiotherapy, yoga, and Pilates. What were the results? “The primary end-point was to evaluate the effectiveness of the association of coenzyme Q10 and alpha lipoic acid in reducing fatigue, expressed as a reduction in Fatigue Severity Scale (FSS), at the second month (T1), of at least 50% (complete response) from the baseline (T0) or at least 20% (partial response) from the baseline (T0). A reduction in FSS < 20% from baseline at T1 was considered as a non-response. A complete FSS response was reached most frequently in the treatment group compared to the control group. An FSS complete response was reached in 62 (53.5%) patients in the treatment group and in two (3.5%) patients in the control group. A reduction in FSS score < 20% from baseline at T1 (non-response) was observed in 11 patients in the treatment group (9.5%) and in 15 patients in the control group (25.9%) (p < 0.0001).” Author's Conclusion “Despite the short follow-up period, we demonstrated a clinical benefit, suggesting the rapid effect of this therapy. On the other hand, because of the short follow-up duration, we do not know if this clinical benefit persists over time. Our results, all based on subjective indices, were definitely in favor of the treatment group.” Dr. Hedberg's Comments on Long COVID, CoQ10, and Alpha Lipoic Acid This study shows promising results in the use of coenzyme Q10 and...

Videos : New Rule: Let the Population Collapse | Real Time with Bill Maher (HBO) – 8:29 The De-Population Bomb – hoover institution (0:43 – 8:15) THE GREAT AWAKENING: PLANDEMIC 3 PRELAUNCH PARTY – (21:00 – 30:20) Gary Null Speaking Out at the NYS Assembly Hearing  (25:00)   Meta-analysis finds less fatigue with CoQ10 supplementation National Yang Ming Chiao Tung University (Taiwan), September 16 2022. The results of a systematic review and meta-analysis of clinical trials, published in Frontiers in Pharmacology, support an anti-fatigue effect among individuals who supplemented with coenzyme Q10. “Coenzyme Q10 (CoQ10) is a popular nutritional supplement and a lipid-soluble antioxidant that is endogenously produced by the human body,” authors I-Chen Tsai of National Yang Ming Chiao Tung University and associates observed. “CoQ10 supplementation has been successfully applied for reducing fatigue in patients with various conditions, including chronic fatigue and fibromyalgia, as well as in healthy subjects.” For their analysis, Tsai colleagues identified 13 randomized, controlled trials that compared fatigue scores of participants who received CoQ10 or a placebo. The trials included a total of 1,126 participants. Analysis of the 13 trials showed a consistent significant effect for CoQ10 in reducing fatigue. When trials that included healthy participants were analyzed separately from trials that included patients with fatigue-associated diseases, both supplemented populations showed decreases in fatigue, however the effects were significant among the unhealthy participants, who may have more severe CoQ10 depletion. Higher CoQ10 doses and longer duration of supplementation were correlated with increased fatigue reduction. The anti-fatigue effect of CoQ10 is unsurprising, given its role in energy production. Chronic fatigue syndrome patients have lower plasma levels of CoQ10 in comparison with healthy subjects. While the body makes some CoQ10, the authors remarked that studies have provided evidence that supplementing with CoQ10 does not affect the body's synthesis of the coenzyme. Researchers identify a potential new approach with a dietary supplement to treat HER2 positive breast cancer Mayo Clinic, September 9, 2022 Researchers at Mayo Clinic have identified an important new pathway by which HER2 positive breast cancers grow and have discovered that a dietary supplement called cyclocreatine may block the growth of HER2 positive breast cancer. Their findings were published in Cell Metabolism. “The HER2 receptor tyrosine kinase, which functions as an ‘on' or ‘off' switch in cellular functions, is a key driver of breast cancer, and is overexpressed in about a quarter of all breast cancers,” says Taro Hitosugi, Ph.D., a pharmacologist at Mayo Clinic and corresponding author of the paper. Dr. Hitosugi and his colleagues decided to explore ways to resolve an unmet clinical need. Their strategy was to develop a treatment to target tumor mitochondrial energy metabolism, which is the process cancer cells use to manipulate energy during cell metabolism in order to grow. Dr. Hitosugi and his colleagues discovered that cyclocreatine, a dietary supplement used in sports drinks, effectively targets mitochondrial creatine kinase 1 enzyme and reduces cancer growth without toxicity. This finding was confirmed in mice models where a patient-derived, trastuzumab-resistant HER2 positive tumors were administered to the mice. “Mitochondrial creatine kinase 1 may be a new drug target for the treatment of HER2 positive breast cancer,” says Matthew Goetz, M.D., director of the Mayo Clinic Breast Cancer research program. “Future clinical trials will be necessary to determine the effectiveness of this drug for HER2 positive breast cancer resistant to standard therapies.” Excessive smartphone screen time linked to earlier puberty onset Gazi University (Turkey), September 16, 2022 Exposure to blue light, via regular use of tablets and smartphones, may alter hormone levels and increase the risk of earlier puberty, according to data from a rat study presented at the Annual European Society for Paediatric Endocrinology Meeting. Longer duration of blue light exposure was associated with earlier puberty onset in the female rats, which also showed reduced levels of melatonin, increased levels of some reproductive hormones and physical changes in their ovaries. Use of blue light-emitting mobile devices has previously been linked to disrupted sleeping patterns in children but these findings suggest there could be additional risks for childhood development and future fertility. The escalating use of blue light-emitting devices, such as tablets and smartphones, has previously been implicated in reducing sleep quality in both children and adults. This is thought to be through disruption of our body clock as blue light inhibits the evening rise in levels of the hormone, melatonin, which prepares our bodies for rest and sleep. Melatonin levels are overall higher during pre-puberty than in puberty, which is believed to play a role in delaying the start of puberty. Puberty is a complex process that involves co-ordination of several body systems and hormones. In recent years, several studies have reported increases in early puberty onset for girls, particularly during the COVID-19 pandemic. The link between blue light exposure and reduced melatonin levels suggests that increased screen time, such as during the pandemic restrictions, may be playing a role in this reported increase. However, it is very difficult to assess this in children. In this study, Dr. Aylin Kilinç Uğurlu and colleagues in Ankara, Turkey, used a rat model to investigate the effects of blue light exposure on reproductive hormone levels and the time of puberty onset. Female rats were divided into three groups of six and exposed to either a normal light cycle, 6 hours or 12 hours of blue light. The first signs of puberty occurred significantly earlier in both groups exposed to blue light, and the longer the duration of exposure, the earlier the onset of puberty. Rats exposed to blue light also had reduced melatonin levels and elevated levels of specific reproductive hormones (estradiol and luteinizing hormone), as well as physical changes in their ovarian tissue, all consistent with puberty onset. At the 12-hour exposure, rats also showed some signs of cell damage and inflammation in their ovaries. Dr. Aylin Kilinç Uğurlu comments, “We have found that blue light exposure, sufficient to alter melatonin levels, is also able to alter reproductive hormone levels and cause earlier puberty onset in our rat model. In addition, the longer the exposure, the earlier the onset.” Fitness trackers reveal links among exercise, memory, and mental health Dartmouth College, September 15, 2022 Exercise can improve your cognitive and mental health—but not all forms and intensities of exercise affect the brain equally. The effects of exercise are much more nuanced, as specific intensities of exercise over a long period of time are associated with different aspects of memory and mental health, according to a new Dartmouth study. The findings are published in Scientific Reports and provide insight into how exercise could be optimized. “Mental health and memory are central to nearly everything we do in our everyday lives,” says lead author Jeremy Manning, an assistant professor of psychological and brain sciences at Dartmouth. “Our study is trying to build a foundation for understanding how different intensities of physical exercise affect different aspects of mental and cognitive health.” The researchers asked 113 Fitbit users to perform a series of memory tests, answer some questions about their mental health, and share their fitness data from the previous year. They expected that more active individuals would have better memory performance and mental health, but the results were more nuanced. People who tended to exercise at low intensities performed better at some memory tasks while those who exercised at a high intensities did better on other memory tasks. Participants who were more intensely active also reported higher stress levels, whereas people who regularly exercised at lower intensities showed lower rates of anxiety and depression. Participants who had been more active over the prior year tended to show better memory performance overall, but the specific areas of improvement depended on which types of activity people did. The researchers found that participants who often exercised at moderate intensities tended to perform better on the episodic memory tasks while participants who often exercised at high intensities did better on the spatial memory tasks. Sedentary participants who seldom exercised tended to perform worse on the spatial memory tasks. The researchers also identified connections between participants' mental health and their memory performance. Participants with self-reported anxiety or depression tended to perform better on the spatial and associative memory tasks, while those with self-reported bipolar disorder tended to perform better on the episodic memorytasks. Participants who reported higher levels of stress tended to perform worse on the associative memory tasks. Positive psychological well-being can improve overall heart health Northwestern University, September 10, 2022 Maintaining positive thoughts and feelings through intervention programs can help patients achieve better overall outcomes when it comes to their cardiovascular health, according to a review paper published in the Journal of the American College of Cardiology. “We addressed how social environment, psychological well-being and the effectiveness of intervention strategies can help strengthen a patient's outlook,” said Darwin R. Labarthe, MD, MPH, Ph.D., professor of Preventive Medicine at Northwestern University Feinberg School of Medicine and the review's lead author. “We focused on whether psychological well-being can be consistently related with a reduced risk of heart disease.” In this review, the authors looked at a growing body of research to examine whether psychological well-being might lead to reduced risk of heart disease. Prospective studies have shown a positive relationship between optimism (one facet of psychological well-being) and heart disease, including a study showing older women in the highest quartile of optimism had a 38 percent reduced risk of heart disease mortality. Additional studies since 2012 have associated a perceived higher purpose in life with lower odds of having a stroke. Optimistic patients sustained healthier diets by consuming more fruits and vegetables, and less processed meats and sweets, leading patients to maintain a healthy BMI. The review authors found that psychological well-being influenced heart health through biological processes, health behaviors and psychosocial resources. Having a strong network of social support also gives patients confidence about their future health and helps them act readily on medical advice, engage in problem solving and take active preventive measures. A likely link is that favorable social environment, known to influence heart disease risk, has also been shown to predict psychological well-being. Milk thistle protects against COPD caused by secondhand smoke Sichuan University, (China), September 11, 2022 According to the U.S. Centers for Disease Control and Prevention (CDC), 15.7 million people suffer from chronic obstructive pulmonary disease (COPD) – a serious respiratory condition which can cause scarring of the lungs, narrowing of the airway and extreme difficulty breathing. Taking enough milk thistle – on a regular basis – can help protect you from harm. Exposure to tobacco smoke – whether through actively smoking or simply inhaling the smoke from another's cigarette – is the primary cause of COPD. Although Western medicine currently offers no cure for COPD, recent studies generate a ray of hope. Groundbreaking new research suggests that milk thistle extracts may not only prevent COPD but, help to treat it. In a study published in the journal Inflammation, researchers exposed mice to the equivalent of 1.5 packs of cigarettes a day for four weeks, creating drastic increases in peribronchial inflammation, thickening of airway walls and airway obstruction. The team found that pretreating the mice with silymarin – the active component of milk thistle – an hour before exposure dramatically decreased inflammatory changes, and cut production of pro-inflammatory chemicals such as TNF-alpha and interleukin. Encouragingly, silymarin also helped safeguard levels of superoxide dismutase, an important disease-fighting antioxidant produced in the body. A year later, the same team of researchers took another, closer look at the workings of milk thistle. And what they found was encouraging. In a study of human bronchial cells published in Scientific Report, the team explored the molecular and cellular mechanisms of silymarin – and found once again that the flavonoid attenuated cigarette smoke-induced upregulation of pro-inflammatory chemicals. And, researchers discovered for the first time that silymarin modulated a certain pathway – known as MAPK – that governs inflammation. The takeaway? The team concluded that silymarin might be “an ideal agent for treating inflammatory pulmonary diseases.” In a third study, recently published in Food and Chemical Toxicology, researchers treated mice with silibinin (a constituent of silymarin) one hour before exposure to cigarette smoke. The team found that the silibinin caused the mice to not only experience the sharp reductions in inflammatory changes seen in earlier studies – but discovered that it also suppressed the scarring and fibrosis that are typical of COPD in humans. This means that silibinin may not only help prevent COPD – but, reverse it! Intriguingly, the silibinin directly affected the expression of a certain pro-inflammatory protein – transforming growth factor beta-1 – that is activated and spurred on by exposure to smoke, making it appear that this compound is custom-designed to protect against secondhand smoke. Milk thistle extracts are available in the form of pills, powders, extracts, liposomes and teas. Look for a high-quality preparation that is standardized to contain 70 to 80 percent silymarin.

Coenzyme Q10 was first identified in 1957. The "Q10" refers to the chemical make-up of the substance. Coenzyme Q10 (CoQ10) is a natural antioxidant synthesized by the body. It comes in two forms: ubiquinol, the active antioxidant form, and ubiquinone, the oxidized form, which the body partially converts to ubiquinol. Coenzyme Q10 is vital in the chain of metabolic chemical reactions that generate energy within cells. Your cells use CoQ10 for growth and maintenance. Today we look at the health benefits of supplementation of Coenzyme Q10. “Only I can change my life. No one can do it for me.”  Carol Burnett 

Exclusive Interview with Dr. Guy Miller, CEO of Edison Pharma. Is there hope for a cure for Mitochondrial Disease? Perhaps the answer is closer than we thought. On July 15, 2008 Edison Pharma and partner Penwest Pharmaceuticals announced that A0001, an “improved” variant of Coenzyme Q10 (CoQ10), has entered Phase 1 clinical development with healthy volunteers. Edison predicts trials in patients with inherited mitochondrial disease will begin in 2009.

Coenzyme Q10 (CoQ10) is a vitamin-like fat-soluble compound made within the body. It is a crucial component in the production of ATP (our body's main source of energy), and also serves as a powerful antioxidant. However, CoQ10 production in the body declines with age, and there are a number of circumstances that require higher amounts of CoQ10 than what our body can make on its own. Listen in this week as Dee discusses the conditions that can benefit from increased amounts of CoQ10, and the best forms of supplemental CoQ10.Link to CoQ10: https://amzn.to/3nE3vwM

On World Heart Health Day 2019, integrative cardiologist, Dr. Jason Kaplan joins us to discuss cardiovascular health issues in Australia and around the world, and evidence based therapies to support heart health such as Ubiquinol, the active form of the powerful antioxidant, Coenzyme Q10 (CoQ10).

“Our pets give us so much. They go with us on adventures, comfort us when we’re down, and help us heal when we’re broken. Every day, they remind us that life should be lived in the moment and with enthusiasm. And most importantly, they love us unconditionally—no questions asked.” -Dr. Stephen Sinatra How Our Pets Help & Heal Our Hearts By Stephen T. Sinatra, M.D., F.A.C.C., F.A.C.N., C.N.S., C.B.T. We tend not to think of pets as a natural remedy for what ails us, but I have found that pets, both in my personal life and the lives of my patients, to be nothing less than that. They are indeed natural remedies. They work by healing with unconditional love. I have often stopped in my busy tracks to give thanks for the blessing of a happy family life, and that includes the dogs who have enriched my life as well. During a medical conference lecture several years ago, one of the doctors in the audience asked whether I had any experience on the healing benefits of companion animals. Although I couldn’t quantify the degree of benefit, I said that many patients indeed have told me over the years how comforting their pets have been to them and how they considered their animals a vital part of recovery. Some said they couldn’t wait to come back to their animals following surgery or hospitalization. Medical research supports the healing benefits of companion animals. Specifically, they have been found to: Significantly increase longevity among people with coronary artery disease who have a heart attack. Reduce blood pressure. Enhance the opportunity to meet other people as well as permit people to be alone without being lonely. About Dr. Stephen Sinatra Dr. Stephen Sinatra is a highly respected and sought-after cardiologist whose integrative approach to treating cardiovascular disease has revitalized patients with even the most advanced forms of illness. His expertise is grounded in more than 40 years of clinical practice, research, and study beginning as an attending physician at Manchester Memorial Hospital (Eastern Connecticut Health Network). His career there included nine years as chief of cardiology, 18 years as director of medical education, seven years as director of echocardiography, three years as director of cardiac rehabilitation, and one year as director of the weight reducing program. In 1987, Dr. Sinatra founded the New England Heart Center. Through it, he became a well-known advocate of combining conventional medical treatments for heart disease with complementary nutritional, anti-aging, and psychological therapies. Today Dr. Sinatra is active primarily as an author, speaker, and advisor for the research and development of nutritional supplements. He joined the Healthy Directions family of experts in 1995. Websites:  / /  ======================================= Helping Your Pet Age the Healthiest Way Possible As a cardiologist who’s spent a career helping human patients, I’ve learned a lot of things about aging and how to get the most out of our years. One of them is just how important our pets are to our own health. For example, did you know that heart attack survivors have better recoveries when they come home to a pet? Or that pets help keep our stress hormones in check, which protects us from disease? I’ve also learned that much of what I know to be true about keeping people healthy can be used to help keep pets healthy, too. When Chewie started getting up in years, I made sure she got plenty of omega-3 fatty acids from healthy fish and nutritional supplements, to keep her joints flexible. I also started giving her regular doses of Coenzyme Q10 (CoQ10) to support the ability of her cells (especially the ones in her heart) to produce and burn energy. I’d seen incredible results prescribing CoQ10 for my human patients. And though I’m not a veterinarian, I saw a noticeable difference in Chewie, as well. Here at Ageless Paws, it’s my goal to share information like this with you—to help you understand not only the health challenges that your dog or cat may face, but also the healthy, natural options you have for addressing them. ============================ 19 Ways Your Dog Makes Your Life Awesome Share on FacebookTweet about this on TwitterShare on LinkedIn By Stephen T. Sinatra, M.D., F.A.C.C., F.A.C.N., C.N.S., C.B.T. If I could bottle and distribute all the benefits that come from dog ownership, I’d be the most popular doc on the planet. That’s because science has clearly shown that sharing your life with a dog is good for your body, mind, and soul. A dog can lick your face—as well as help you lick a long list of chronic ailments. In a nutshell, dogs are awesome! Here are 19 human reasons why dogs are the best (that’s 133 dog reasons): 1. Dogs Dig Walking. As a cardiologist, I love anything that encourages folks to walk on a regular basis. And I’ve never met a dog that doesn’t want or need to be walked daily. Not coincidentally, research has shown that dog owners walk 22 minutes more a day than people without dogs. All those extra daily steps you take while walking your dog can make a real difference in your health and well-being. Your Pup Protects Your Heart. Just like your dog will protect his favorite toy or his food bowl, he will also protect your heart. Dog ownership has been found to lower your risk of cardiovascular disease and reduce your risk of cardiovascular and all-cause death because dogs encourage us to engage in more outdoor activities, keep us more active throughout the day, and prevent us from being lonely.   Petting Your Pooch Boosts Immunity. Immunoglobulin A (IgA) is one of the most common antibodies in the body. Higher levels of IgA indicate a robust immune system that can help you fight off illnesses. As it turns out, simply petting a dog raises the level of IgA in your saliva. Rex Helps You Relax. Interacting with a dog can increase the amount of oxytocin in your body. Oxytocin plays a key role in relaxation and feelings of well-being. So, after a stressful day at work or when you need some relief from the pressures of caring for a loved one, playing with your dog is a fun and natural way to unwind. Canine Companions Calm the Mind. A dog’s ever-present love can be a calming, reassuring factor in anyone’s life. And particularly for those dealing with post-traumatic stress disorder (PTSD), anxiety, or depression, there is a wealth of evidence suggesting that service dogs or therapy dogs can dramatically improve mental health, enhance sleep quality, and boost feelings of social well-being. Fluffy Will Find You Friends—Or Get You a Date… I have a colleague who owns three Beagles. When she moved to a different city, she says she got to know practically all of her neighbors while on her daily dog walks. Owning a pet makes you seem more social, which can encourage others to stop and strike up a conversation with you. And listen up, single guys: Women are more willing to give their phone numbers to men with dogs. …But Fido Can ALSO Make You Feel Safe. I’ve talked to a lot of women, and even some men, who don’t want to walk or jog outside alone, because they’re worried about their safety. A big dog can be a great deterrent to those who want to harass you. Your Dog Helps You Follow Doctor’s Orders. This one’s great news for me and other doctors—as well as for all dog owners. A study from the American Humane Association shows that dogs motivate children fighting cancer to follow their doctor’s instructions. While this particular study focuses on kids, the concept likely applies to adults as well. Dogs Are Better Than Pain Meds. As opioid addiction becomes an increasingly serious problem, it’s vital that doctors find alternative ways for patients to handle pain. One study has shown that people who’ve undergone total joint replacement surgery needed 28 percent less pain medication when they had contact with therapy dogs. Hounds Keep You Hopping. Because dogs are, by nature, creatures of habit, they love a good routine. They like to get up early in the morning, rain or shine. They often demand food at certain times of the day. And, of course, dogs need to go outside to do their business early and often. Living with a dog will encourage you to follow a regular schedule as well, which improves and enhances your health. Dogs Are Happy to Help Everyone. Giving to others through volunteerism is an important way to connect yourself to your community. Volunteering your time to an important cause also boosts self-esteem and instills a sense of purpose. If you get your pet trained as a therapy dog you can both volunteer at hospitals, schools, prisons, and other places where people might need emotional support. In the process of helping others, you’ll also help yourself. See Spot, Then Smile. As far as I’m concerned, it’s nearly impossible to watch a happy dog at play and not break into a smile. Since smiling offers both psychological and physical benefits, from improving your mood to lowering your heart rate, living with a funny furry friend allows you ample opportunity to turn your frown upside down. No One Hates Dogs—Except Burglars. Home security experts, as well as former burglars themselves, will tell you that the best way to protect your home is with a dog. And it’s not because dogs can bite. It’s because they can bark, alerting you to the fact that someone is invading their territory. So, you don’t need to adopt a giant guard dog to feel more secure in your home. In most cases, it simply takes a barking dog (even a wee little one) to scare off intruders. Trained Dogs Can Do Just About Anything for You! Most dogs are quite trainable and actually like the training process, since it gives them purpose. The range of tasks that a dog can learn to perform for you is truly amazing. Want your dog to fetch you a drink from the fridge? Once properly trained, your bulldog can become your butler! Although it requires specialized training, some dogs can even be used for screening people for lung, bowel, and ovarian cancer. Kids Grow Up Healthier with a Dog Around. Just about every kid wants a dog to love. In return, dogs can actually boost kids’ health, especially if dogs are introduced to the home when children are young. Kids who are at risk of developing eczema have been shown to have a reduced risk if they have a dog living with them. In addition, children at risk of developing allergies and asthma also face a reduced risk when their household includes a dog while they are infants. That means having a family dog can make your whole family healthier and happier. Dogs Bring Out the Adult in You. As great as dogs are, they can’t take care of themselves. In exchange for their unwavering loyalty, dogs need us to be responsible for them and patient with them. Learning how to exercise responsibility and patience for your dog—and throughout the rest of your life—pays huge dividends personally and professionally. You’re Never Alone with a Dog. Loneliness can be downright debilitating. It can actually cause your brain to go haywire. Enough social isolation can even make you hallucinate and imagine that you see ghosts! Luckily, a dog is a constant companion—morning, noon, and night. Even when your friends don’t have time for a visit, your dog always has time for you. Watch Rover Roll Over—And Other Fun Stuff. I’ve always found it much more enjoyable to watch my dogs play in the backyard than to sit in front of the TV. Dogs’ enthusiasm for life is aspirational, and their energy is contagious. It’s even more fun when you also get involved in a game of fetch or tug-of-war. There Is a Reason Dogs Are Called Man’s Best Friend. Perhaps I’ve saved the best for last: Dogs epitomize unconditional love. On a daily basis, dogs will prove their steadfast devotion by greeting you as if you just returned from battle even though you only went to the grocery store or refusing to leave your side when you come down with a cold. Then there’s even one dog who traveled 2,800 miles to reunite with its beloved family. When you have that kind of love walking at your side or resting at your feet, life is awesome and anything is possible! how pets heal your heart, do

If you, a family member or friend have been diagnosed and suffer from migraine headaches, you might want to listen & share this podcast. Dr. Madrid discusses natural approaches he takes with his patients to help prevent and control their migraines. See disclaimer below! Based on my article: https://iherb.co/3pJ5kNUC Some commonly recognized triggers of migraines: -Cheeses (due to the amino acid tyramine) -Wine (due to the presence of sulfites) -Food additives such as MSG, food dyes and preservatives -History of head trauma and concussion -Sleep deprivation -Sleep apnea -Chronic stress -Menstruation/Hormone changes -Caffeine can trigger in some, while preventing in others -Dehydration -Artificial sweeteners such as aspartame (NutraSweet), found in essentially all diet or zero-calorie carbonated beverages. Recommended Supplements: -Riboflavin – Adults - 400 mg daily. Pediatrics - 100 to 400 mg daily. -Magnesium chelate (i.e malate, citrate, etc.) –125 mg to 500 mg daily -Ginger – 250 mg to 500 mg once or twice daily. -Omega 3-Fish Oil – 2,000 to 4,000 mg daily. Divide into twice a day dosing. -Coenzyme Q10 (CoQ10) – 100 mg to 300 mg daily -Alpha Lipoic Acid – 600 to 800 mg daily to prevent migraines, okay to take in divided doses. -Melatonin –3 mg to 10 mg each night 1-2 hours before bed. -Feverfew – 250 mg once or twice per day. -Butterbur – 75 mg once to three times daily. Other Useful Prevention Measures -Clean up your diet, avoid toxins -Optimize Gut health -Regular aerobic exercise -Yoga -Acupuncture -Meditation -Chamomile essential oil has shown benefit when applied to the upper lip or when used with a diffuser -Lavender essential has shown benefit when applied to the upper lip or when used with a diffuser Instagram: @ericmadridmd Twitter: @ericmadridmd Facebook: facebook.com/ericmadridmd DISCLAIMER: This podcast is not intended to provide a diagnosis, treatment or medical advice. Opinions by Dr. Madrid are for INFORMATIONAL purposes only. Please consult with your physician regarding your situation as each person is unique.

After spending years directing urinary and salivary hormone testing, analytical chemist Mark Newman set out to combine the best of both worlds with the DUTCH (Dried Urine Test for Comprehensive Hormones). For the past couple of years, we’ve been happily using the DUTCH as a tool for improving health and performance in athletes as part of our Elite Performance Program. In this interview, Mark discusses the recent expansion and improvement of the DUTCH to include the cortisol awakening response (CAR), and several markers related to hormone and neurotransmitter metabolism. Here’s the outline of this interview with Mark Newman: [00:00:54] DUTCH (Dried Urine Test for Comprehensive Hormones). [00:02:49] Cortisol clearance. Video: Tutorial on cortisol. [00:03:32] 8-Hydroxy-2-deoxyguanosine (8-OH-dG). [00:05:02] Obesity. [00:05:21] Cushing’s syndrome. [00:05:44] Fat sequesters hormones. [00:08:58] Thyroid and cortisol clearance. [00:09:20] Studies: 1, 2, and 3. [00:11:51] Circadian rhythm. [00:12:39] Cortisol awakening response (CAR). [00:14:31] Studies: References 1, 2, 3, 4, and 5.                  [00:16:34] Why you can't see the CAR with urine. [00:18:08] Correlations between glucose, c-peptide, and cortisol. [00:19:50] The CAR is a proxy. [00:21:30] Clinical implications of the CAR. [00:25:28] 8-OH-dG on PubMed. [00:26:43] Joergensen, Anders, et al. “Association between urinary excretion of cortisol and markers of oxidatively damaged DNA and RNA in humans.” PLoS One 6.6 (2011): e20795. [00:27:00] Melatonin is an antioxidant. [00:27:14] 4-OH oestrogen metabolite. Video: Estrogen Tutorial. [00:28:26] Will there be a full OAT? [00:28:53] Neurotransmitters. [00:29:57] Kynurenine pathway. Article: Electrons, Neurotoxins, NAD+, and Mitochondria by Tommy Wood MD, PhD. [00:31:01] NAD and vitamin B6, xanthurenic acid. [00:32:01] MMA, folate. [00:32:52] Article: New Research: Birth Control Pill, Depression and Autoimmunity by Kelly Brogan MD. [00:33:37] Hydroxymethylglutarate (HMG) is the precursor to Coenzyme Q10 (CoQ10) production. [00:35:41] Evidence-based markers. [00:37:09] Doing experiments, DIM. [00:39:14] Adding markers, value vs noise. [00:40:58] Great Plains OAT (Organic Acids Test). [00:41:15] Podcast: The Cortisol Awakening Response with Mark Newman, MS. [00:41:39] Machine Learning. Podcasts: How to Teach Machines That Can Learn with Dr. Pedro Domingos, PhD and How “Machine Learning” Can Predict Your Blood, Urine, Stool, Saliva & More! With Dr. Tommy Wood. [00:42:16] Mass spec, immunoassay test. [00:45:17] Predicting the CAR. [00:45:56] Linear correlations. [00:50:06] Receptor activity, house analogy. [00:51:10] Elite Performance Program and the 7-Minute Analysis. [00:52:11] Getting the DUTCH done. [00:53:50] The Institute for Functional Medicine (IFM). [00:55:07] The process of elimination. [00:55:43] Precision Analytical at dutchtest.com.

Rheumatoid arthritis (RA) is characterized by an immune response that triggers the overproduction of proinflammatory cytokines, causing joint destruction and erosion. Coenzyme Q10 (CoQ10) is an antioxidant which has been studied and shown to protect against inflammation related to coronary artery disease, diabetes, and more. This is the first study to examine whether the benefits of CoQ10 extent to RA.

Heather & Terry talk about the anti-aging properties of Coenzyme Q10 (CoQ10) and the effects of aging on developing wisdom.

The amazing benefits of Coenzyme Q10, Learn the ABCs of motivation,(part 1 of 4), Download the Exercise Routine, Workout Guide and log for Sculpt Cycle#14 Body Fat Blast from Fitness Makeover Program... Proven steps to improve your health, body, productivity, focus and self-esteem! No nonsense tips, advice and instruction in three major subjects: Motivation, Exercise, Nutrition. Stay motivated, workout less, eat more and get the body you want! Visit fitgirlpodcast.com for more. Launched in 2007, FitGirl one of the longest running podcasts! Fitness Guru Kira Langolf has an international following and is best known for her proven body changing programs, personal development seminars and Fitness Makeover Workshops. Author of the groundbreaking book: “MINDSET MAKEOVER: Stay Motivated, Get the Body You Want and Live the Life of Your Dreams!” Kira tells you exactly which exercises and diets are a waste of time and which to use to get your best body ever!

Exclusive Interview with Dr. Guy Miller, CEO of Edison Pharma. On July 15, 2008 Edison Pharma and partner Penwest Pharmaceuticals announced that A0001, an "improved" variant of Coenzyme Q10 (CoQ10), has entered Phase 1 clinical development with healthy volunteers. Edison predicts trials in patients with inherited mitochondrial disease will begin in 2009.