Podcasts about Essential tremor

Essential tremor is the most common movement disorder, although it is often misdiagnosed. A careful history and clinical examination for other neurologic findings, such as bradykinesia, dystonia, or evidence of peripheral neuropathy, can reveal potential alternative etiologies. Knowledge about epidemiology and associated health outcomes is important for counseling and monitoring for physical impairment and disability. In this episode, Lyell Jones, MD, FAAN, speaks with Ludy C. Shih, MD, MMSc, FAAN, author of the article “Essential Tremor” in the Continuum® August 2025 Movement Disorders issue. Dr. Jones is the editor-in-chief of Continuum: Lifelong Learning in Neurology® and is a professor of neurology at Mayo Clinic in Rochester, Minnesota. Dr. Shih is clinical director of the Parkinson's Disease and Movement Disorders Center at Beth Israel Deaconess Medical Center in Boston, Massachusetts. Additional Resources Read the article: Essential Tremor Subscribe to Continuum®: shop.lww.com/Continuum Earn CME (available only to AAN members): continpub.com/AudioCME Continuum® Aloud (verbatim audio-book style recordings of articles available only to Continuum® subscribers): continpub.com/Aloud More about the American Academy of Neurology: aan.com Social Media facebook.com/continuumcme @ContinuumAAN Host: @LyellJ Guest: @ludyshihmd Full episode transcript available here Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum. Thank you for listening to Continuum Audio. Be sure to visit the links in the episode notes for information about earning CME, subscribing to the journal, and exclusive access to interviews not featured on the podcast. Dr Jones: This is Dr Lyell Jones, Editor-in-Chief of Continuum: Lifelong Learning in Neurology. Today, I'm interviewing Dr Ludy Shih, who recently authored an article on essential tremor for our latest issue of Continuum on movement disorders. Dr Shih is an associate professor of neurology at Harvard Medical School and the clinical director of the Parkinson's Disease and Movement Disorder Center at Beth Israel Deaconess Medical Center in Boston. Dr Shih, welcome, and thank you for joining us today. Why don't you introduce yourself to our listeners? Dr Shih: Thank you, Dr Jones, for having me. It's a real pleasure to be here on the podcast with you. I'm a neurologist, I trained in movement disorders fellowship, and I currently see patients and conduct clinical research. We offer a variety of treatments and diagnostic tests for our patients with movement disorders. And I have developed this interest, a clinical research interest in essential tremor. Dr Jones: And so, as an expert in essential tremor, the perfect person to write such a really spectacular article. And I can't wait for our listeners to hear more about it and our subscribers to read it. And let's get right to it. If you had, Dr Shih, a single most important message for our listeners about caring for patients with essential tremor, what would that message be? Dr Shih: Yeah, I think the takeaway that I've learned over the years is that people with essential tremor do develop quite a few other symptoms. And although we propose that essential tremor is this pure tremor disorder, they can experience a lot of different comorbidities. Now, there is some debate as to whether that is expected for essential tremor or is this some part of another syndrome, which we may talk about later in the interview. But the fact of the matter is, it's not a benign condition and people do experience some disability from it. Dr Jones: And I think that speaks to how the name of this disorder has evolved over time. right? You point out in your article, it used to be called benign essential tremor or benign familial tremor. But it's really not so straightforward as it. And fairly frequently these symptoms, the patient's tremor, can be functionally limiting, correct? Dr Shih: That is correct. In fact, the reason I probably started getting interested in essential tremor was because our center had been doing a lot of deep brain stimulation for essential tremor, which is remarkably effective, especially for tremor that reaches an amplitude that really no oral medication is going to satisfyingly treat. And if you have enough upper limb disability from this very large-amplitude tremor, a surgical option may make a lot of sense for a lot of patients. And yet, how did they get to that point? Do they continue to progress? These were the sort of interesting questions that got raised in my mind as I started to treat these folks. Dr Jones: We'll come back to treatment in just a minute here, because there are many options, and it sounds like the options are expanding. To start with the diagnosis- I mean, this is an extraordinarily common disorder. As you point out, it is the most common movement disorder in the US and maybe the world, and yet it seems to be underrecognized and frequently misdiagnosed. Why do you think that is? Dr Shih: Great question. It's been pretty consistent, with several case series over the decades showing a fairly high rate of quote/unquote “misdiagnosis.” And I think it speaks to two things, probably. One is that once someone sees a postural and kinetic tremor of the arms, immediately they think of essential tremor because it is quite common. But there's a whole host of things that it could actually be. And the biggest one that we also have to factor in is also the heterogeneity of the presentation of Parkinson's disease. Many people, and I think increasingly now these days, can present with not a whole lot of the other symptoms, but may present with an atypical tremor. And it becomes actually a little hard to sort out, well, do they have enough of these other symptoms for me to suspect Parkinson's, or is the nature of their tremor suspicious enough that it would just be so unusual that this stays essential tremor and doesn't eventually develop into Parkinson's disease? And I think those are the questions that we all still grapple with from time to time in some of our clinics. Dr Jones: Probably some other things related to it with, you know, our understanding of the pathophysiology and the availability of tests. And I do want to come back to those questions here in just a minute, but, you know, just the nomenclature of this disorder… I think our clinical listeners are familiar with our tendency in medicine to use words like essential or idiopathic to describe disorders or phenomena where we don't understand the precise underlying mechanism. When I'm working with our trainees, I call these “job-security terms” because it sounds less humbling than “you have a tremor and we don't know what causes it,” right? So, your article does a really nice job outlining the absence of a clear monogenic or Mendelian mechanism for essential tremor. Do you think we'll ever have a eureka moment in neurology for this disorder and maybe give it a different name? Dr Shih: It's a great question. I think as we're learning with a lot of our neurologic diseases---and including, I would even say, Parkinson's disease, to which ET gets compared to a lot---there's already now so much more known complexity to something that has a very specific idea and concept in people's minds. So, I tend to think we'll still be in an area where we'll have a lot of different causes of tremor, but I'm hopeful that we'll uncover some new mechanisms for which treating or addressing that mechanism would take care of the tremor in a way that we haven't been able to make as much progress on in the last few decades as maybe we would have thought given all the advances in in technology. Dr Jones: That's very helpful, and we'll be hopeful for that series of discoveries that lead us to that point. I think many of our listeners will be familiar with the utility---and, I think, even for most insurance companies, approval---for DAT scans to discriminate between essential tremor and Parkinsonian disorders. What about lab work? Are there any other disorders that you commonly screen for in patients who you suspect may have essential tremor? Dr Shih: Yeah, it's a great question. And I think, you know, I'm always mindful that what I'm seeing in my clinic may not always be representative of what's seen in the community or out in practice. I'll give an example. You know, most of the time when people come to the academic Medical Center, they're thinking, gosh, I've tried this or that. I've been on these medicines for the last ten years. But I've had essential tremor for twenty years. We get to benefit a little bit from all that history that's been laid down. And so, it's not as likely you're going to misdiagnose it. But once in a while, you'll get someone with tremor that just started a month ago or just started, you know, 2 or 3 months ago. And you have to still be thinking, well, I've got to get out of the specialist clinic mindset, and think, well, what else really could this be? And so, while it's true for everybody, moreso in those cases, in those recent onset cases, you really got to be looking for things like medications, electrolyte abnormalities, and new-onset thyroid disorder, for example, thyroid toxicosis. Dr Jones: Very helpful. And your article has a wonderful list of the conditions to consider, including the medications that might be used for those conditions that might result or unmask a tremor of a different cause. And I think being open-minded and not anchoring on essential tremor just because it's common, I think is a is a key point here. And another feature in your article that I really enjoyed was your step-by-step approach to tremor. What are those steps? Dr Shih: Well, I think you know first of all, tremor is such common terminology that even lay people, patients, nonclinicians will use the word “tremor.” And so, it can be tempting when the notes on your schedule says referred for tremor to sort of immediately jump to that. I think the first step is, is it tremor? And that's really something that the clinician first has to decide. And I think that's a really important step. A lot of things can look superficially like tremor, and you shouldn't even assume that another clinician knows what tremor looks like as opposed to, say, myoclonus. Or for example a tremor of the mouth; well, it actually could be orolingual or orobuccal dyskinesia, as in tardive dyskinesia. And another one that tremor can look like is ataxia. And so, I think- while they sound obvious to most neurologists, perhaps, I think that---especially in the area of myoclonus, where it can be quite repetitive, quite small amplitude in some conditions---it can really resemble a tremor. And so, there are examples of these where making that first decision of whether it's a tremor or not can really be a good sort of time-out to make sure you're going down the right path to begin with. And I think what's helpful is to think about some of the clinical definitions of a tremor. And tremor is really rhythmic, it's oscillatory. You should see an agonist and antagonist muscle group moving back and forth, to and fro. And then it's involuntary. And so, I think these descriptors can really help; and to help isolate, if you can describe it in your note, you can probably be more convinced that you're dealing with the tremor. The second step that I would encourage people to really consider: you've established it's a tremor. The most important part exam now becomes, really, the nontremor part of the exam. And it should be really comprehensive to think of what else could be accompanying this, because that's really how we make diagnosis of other things besides essential tremor. There really should be a minimum of evidence of parkinsonism, dystonia, neuropathy, ataxia- and the ataxia could be either from a peripheral or central nervous system etiology. Those are the big four or five things that, you know, I'm very keen to look for and will look pretty much in the head, neck, the axial sort of musculature, as well as the limbs. And I think this is very helpful in terms of identifying cases which turn out to have either, say, well, Parkinson's or even a typical Parkinson disorder; or even a genetic disorder, maybe even something like a fragile X tremor ataxia syndrome; or even a spinal cerebellar ataxia. These cases are rare, but I think if you uncover just enough ataxia, for example, that really shouldn't be there in a person, let's say, who's younger and also doesn't have a long history of tremor; you should be more suspicious that this is not essential tremor that you're dealing with. And then the last thing is, once you've identified the tremor and you're trying to establish, well, what should be done about the tremor, you really have to say what kind of tremor it is so that you can follow it, so you can convey to other people really what the disability is coming from the tremor and how severe the tremor is. So, I think an example of this is, often in the clinic, people will have their patients extend their arms and hands and kind of say, oh, it's an essential tremor, and that's kind of the end of the exam. But it doesn't give you the flavor. Sometimes you'll have a patient come in and have a fairly minimal postural tremor, but then you go out, take those extra few seconds to go grab a cup of water or two cups of water and have them pour or drink. And now all of a sudden you see this tremor is quite large-amplitude and very disabling. Now you have a better appreciation of what you really need to do for this patient, and it might not be present with just these very simple maneuvers that you have at bedside without props and items. And then the severity of it; you know, we're so used to saying mild, moderate, severe. I think what we've done in the Tremor Research Group to use and develop the Essential Tremor Rating Assessment Scale is to get people used to trying to estimate what size the tremor is. And you can do that by taking a ruler or developing a sense of what 1 centimeter, 2 centimeters, 3 centimeters looks like. I think it'd be tremendously helpful too, it's very easy and quick to convey severity in a given patient. Dr Jones: I appreciate you, you know, having a patient-centered approach to the- how this is affecting them and being quantitative in the assessment of the tremor. And that's a great segue to a key question that I run into and I think others run into, which is when to initiate therapy? You know, if you see a patient who, let's say they have a mild tremor or, you know, something that quantitatively is on the mild end of the spectrum, and you have, you know, a series of options… from a medication perspective, you have to say, well, when does this across that threshold of being more likely to benefit the patient than to harm the patient? How do you approach that question? What's your threshold for starting medication? Dr Shih: Yeah. You know, sometimes I will ask, because---and I know this sounds like a strange question---because I feel like my patients will come for a couple of different reasons. Sometimes it's usually one over the other. I think people can get concerned about a symptom of a tremor. So, I actually will ask them, was your goal to just get a sense for what this tremor is caused by? I understand that many people who develop tremor might be concerned it might be something like Parkinson's disease. Or is this also a tremor that is bothering you in day-to-day life? And often you will hear the former. No, I just wanted to get checked out and make sure you don't think it's Parkinson's. It doesn't bother me enough that I want to take medication. They're quite happy with that. And then the second scenario is more the, yeah, no, it bothers me and it's embarrassing. And that's a very common answer you may hear, may be embarrassing, people are noticing. It's funny in that many people with essential tremor don't come to see a doctor or even the neurologist for many years. And they will put up with it for a very long time. And they've adopted all sorts of compensatory strategies, and they've just been able to handle themselves very admirably with this, in some cases, very severe tremor. So, for some of them, it'll take a lot to come to the doctor, and then it becomes clear. They said, I think I'm at the point where I need to do something about this tremor. And so, I think those three buckets are often sort of where my patients fall into. And I think asking them directly will give you a sense of that. But you know, it can be a nice time to try some as-needed doses of something like Propranolol, or if it's something that you know that they're going to need something on day-to-day to get control of the tremor over time, there are other options for that as well. Dr Jones: Seems like a perfect scenario for shared decision-making. Is it bothersome enough to the patient to try the therapy? And I like that suggestion. That's a nice pearl that you could start with an a- needed beta blocker, right, with Propranolol. And this is a question that I think many of us struggle with as well. If you've followed a patient with essential tremor for some time and you've tried different medications and they've either lost effectiveness or have intolerable adverse effects, what is your threshold for referring a patient for at least considering a surgical neurostimulator therapy for their essential tremor? Dr Shih: Yeah, so surgical therapies for tremor have been around for a long time now, since 1997, which was when it was approved by the FDA for essential tremor and Parkinson tremor. And then obviously since then, we have a couple more options in the focus ultrasound thalamotomy, which is a lesioning technique. When you have been on several tremor medications, the list gets smaller and smaller. It- and then chance of likely satisfying benefit from some of these medications can be small and small as you pass through the first and second line agents and these would be the Propranolol and the primidone. And as you say, quite a few patients- it's estimated between 30 to 50% of these patients end up not tolerating these first two medications and end up discontinuing them. Some portion of that might also be due to the fact that some of our patients who have been living with essential tremor for decades now, to the point that their tremor is getting worse, are also getting older. And so, polypharmacy and/or some of the potential side effects of beta blockers and anticonvulsants like primidone may be harder to bear in an older adult. And then as you talk about in the article, there's some level of evidence for topiramate, and then from there a number of anticonvulsants or benzos, which have even weaker evidence for them. It's a personal decision. As I tell folks, look, this is not going to likely extend your life or save your life, but it's a quality of life issue. And of course, if there are other things going on in life that need to be taken care of and they need that kind of care and attention, then, you know, you don't need to be adding this to your plate. But if you are in the position where those other things are actually okay, but quality of life is really affected by your being unable to use your upper limbs in the way that you would like to… A lot of people's hobbies and applications are upper limb-based, and enjoying those things is really important. Then I think that this is something- a conversation that we begin and we begin by talking about yes, there are some risks involved, but fortunately this is the data we have on it, which is a fairly extensive experience in terms of this is the risk of, you know, surgery-related side effects. This is the risk of if you're having stimulation from DBS stimulation-related side effects, which can be adjustable. It's interesting, I was talking with colleagues, you know, after focused ultrasound thalamotomy was approved. That really led more people to come to the clinic and start having these discussions, because that seemed like a very the different sort of approach where hardware wasn't needed, but it was still a surgery. And so, it began that conversation again for a bunch of people to say, you know, what could I do? What could I tolerate? What would I accept in terms of risk and potential benefit? Dr Jones: Well, I think that's a great overview of a disorder where, you know, I think the neurologist's role is really indispensable. Right? I mean, you have to have this conversation not just once, this is a conversation that you have over time. And again, I really want to refer our listeners to this article. It's just a fantastic overview of a common disorder, but one where I think there are probably gaps where we can improve care. And Dr Shih, I want to thank you for joining us, and thank you for such a great discussion on essential tremor. I learned a lot from your article, and I learned even more from the interview today. I suspect our readers and listeners will too. Dr Shih: Well, thank you again for the invitation and the opportunity to kind of spread the word on this really common condition. Dr Jones: Again, we've been speaking with Dr Ludy Shih, author of a fantastic article on essential tremor in Continuum's latest issue on movement disorders. Please check it out, and thank you to our listeners for joining today. Dr Monteith: This is Dr Teshamae Monteith, Associate Editor of Continuum Audio. If you've enjoyed this episode, you'll love the journal, which is full of in-depth and clinically relevant information important for neurology practitioners. Use the link in the episode notes to learn more and subscribe. AAN members, you can get CME for listening to this interview by completing the evaluation at continpub.com/audioCME. Thank you for listening to Continuum Audio.

Essential Tremor is the most common brain disease you've never heard of - affecting more than 10 million Americans.   In this special episode, we her the story of Wall Street executive Alexandra Lebenthal, who suffered from Essential Tremor since child hood, and her decision to be one of the first patients in America to undergo a high-tech new, non-invasive treatment using focused ultrasound.     For more information, transcripts, and all episodes, please visit https://thisisyourbrain.com    For more about Weill Cornell Medicine Neurological Surgery, please visit https://neurosurgery.weillcornell.org 

UPMC Neurologist Dr. Priya Cardone discusses essential tremor disorder full 458 Mon, 31 Mar 2025 17:10:13 +0000 KBXWrURCYfwv0t8ZgVFOfZ7kMXrIEDb4 upmc,emailnewsletter,upmc marty,news,a-newscasts,top picks,arts,design Marty Griffin upmc,emailnewsletter,upmc marty,news,a-newscasts,top picks,arts,design UPMC Neurologist Dr. Priya Cardone discusses essential tremor disorder On-demand selections from Marty's show on Newsradio 1020 KDKA , airing weekdays from 10 a.m. to 2 p.m. 2024 © 2021 Audacy, Inc. News News News News news News News News Arts Design News News False https://player.amperwa

Journalist and author Sonya Voumard on the rare neurological condition that has stalked her since a family tragedy during her childhood.Sonya Voumard was on the precipice of teen hood when her father suddenly and unexpectedly died.In the months following his death, Sonya developed a tremor in her right hand, not dissimilar to the shaking she sometimes noticed in her father when he was cutting the top off her boiled egg at breakfast.The tremor got worse as she got older, but working late nights as a dogged journalist, fuelled by coffee and nicotine, it almost became a badge of honour for Sonya.One day, though, a terrifying moment while driving set her off on a decades-long quest through Australia's medical system.This episode of Conversations explores disability, neurological condition, brain surgery, experimental medicine, grief, untimely death, death of a father, journalism, Port Arthur massacre, Mabo, Melbourne, substance abuse, alcohol, shaking, Parkinson's, being queer, unexplained medical anomalies, neurosurgeon, neuroscience, St Vincent's hospital, writing, books, memoir, Dystonia, essential tremor, familial tremor, MS, multiple sclerosis, medical system, medicare, public versus private patients.Tremor: a movement disorder in a disordered world is published by Finlay Lloyd.Learn more about dystonia from the Dystonia Network of Australia.

Essential tremor is the most common movement disorder in humans, and its causes are among the most mysterious. It's a neurological condition that causes involuntary shaking. It can begin in one's 20s or 30s, or much later in life. Dr. Natalie Diaz treats essential tremors. Its origins may be unknown, but there are treatments. The first step is to talk to your doctor to rule out other forms of tremor because there are many.

Dr. Joe Sirven discusses mental sharpness and a breakthrough treatment for essential tremors.

In honor of Essential Tremor Awareness month, this episode of Curing with Sound, features Michael Werner, a healthcare attorney, who has lived with essential tremor most of his life. After years of struggling with increasingly debilitating tremors that affected daily activities like eating and cooking, he chose to have a noninvasive focused ultrasound procedure. Michael's story highlights the critical gap in awareness about focused ultrasound technology, even among healthcare professionals. Despite having tremors since high school that progressively worsened with age, doctors initially recommended only medication or deep brain stimulation surgery without mentioning focused ultrasound as an option. It wasn't until a neurosurgeon at NIH asked why he wasn't considering focused ultrasound that Michael learned about this groundbreaking alternative treatment, which ultimately provided immediate and significant symptom improvements with minimal side effects. Key points include: Immediate Results – Michael's condition improved immediately following the two-hour focused ultrasound procedure, allowing him to write his name and hold objects steadily for the first time in years. Confidence in the Procedure – After successfully treating his right hand nine months ago, Michael plans to return for bilateral treatment to improve his left side. Advocacy & Awareness – As both a patient and healthcare lawyer, Michael participates in advocacy efforts, including a congressional fly-in, to raise awareness about focused ultrasound treatment among policymakers and potential patients. EPISODE TRANSCRIPT ---------------------------- QUESTIONS? Email podcast@fusfoundation.org if you have a question or comment about the show, or if you would you like to connect about future guest appearances.  Email info@fusfoundation.org if you have questions about focused ultrasound or the Foundation.  FUSF SOCIAL MEDIA LinkedIn X Facebook Instagram TikTok YouTube FUSF WEBSITE https://www.fusfoundation.org SIGN UP FOR OUR FREE NEWSLETTER https://www.fusfoundation.org/newsletter-signup/ READ THE LATEST NEWSLETTER https://www.fusfoundation.org/the-foundation/news-media/newsletter/ DOWNLOAD "THE TUMOR" BY JOHN GRISHAM (FREE E-BOOK) https://www.fusfoundation.org/read-the-tumor-by-john-grisham/  

Carolyn McMakin, MA, DC Kim Pittis, LCSP, (PHYS), MT 00:14 Exciting Case Reports and Research Updates 02:03 Technical Glitches and Presentation Preparations 02:42 Deep Dive into Hip and Pelvis Presentation 04:04 Case Studies and Certification Process 07:41 CE Mark and Aftermarket Data 11:41 Metal Allergies in Surgical Implants 17:39 Phantom Gallbladder Pain Case Study 26:42 Listening to Patients' Stories 29:25 Managing Unattended Treatments 30:08 Leaky Gut and CustomCare 31:16 Radiation Treatment and Vagus Nerve 32:08 FSM Patient Monitoring 36:36 Shoulder Pain and Treatment Protocols 38:38 Frozen Shoulder Challenges 41:52 Coracoid Process Surgery 46:45 Liability Concerns with EyeCare 50:46 Essential Tremor and Dopamine Support In the fast-evolving world of integrative medicine, tools and methodologies that confirm positive patient outcomes are invaluable. Frequency-Specific Microcurrent (FSM) stands out as a promising approach, providing noteworthy insights and clinical benefits. Based on recent discussions between Dr. McMakin and Kim Pittis, this post delves into practical applications of FSM and how medical practitioners can incorporate it into their practice for enhanced patient care. ### Standardizing FSM Protocol for Common Conditions Dr. McMakin emphasizes the importance of successful application of FSM protocols, specifically in dealing with complex cases such as frozen shoulder and post-surgical complications. When encountering resistance in increasing shoulder mobility, practitioners must ensure that the nerve has been adequately treated for inflammation and scarring. Start with reducing inflammation in the nerve (40 and 10 frequency) before addressing scar tissue and mechanics. For those dealing with leaky gut syndrome, Dr. Menik suggests a protocol of FSM treatments such as 1and 24 and 22, emphasizing a five-day consecutive treatment regimen. This procedure should be undertaken with adequate supervision and alignment with state laws concerning unattended treatments. It is important to monitor the patient for any signs of discomfort during the treatment to ensure optimal results, especially if running the device unattended. ### Integrating FSM for Complex Cases Dr. McMakin shares a compelling case involving a patient with knee replacements. Understanding the difference in metal types—titanium versus chromium cobalt—can crucially impact postoperative recovery. This differentiation is pivotal due to varying incidences of metal allergies. For patients with known sensitivities or unexplained inflammation post-surgery, practitioners should consider the metal type as a contributing factor to symptoms. In another case involving a patient with phantom gallbladder pain, the presence of metal clips left post-surgery required unique approaches involving FSM for treating metal toxicity. Such cases highlight the importance of considering not just the symptoms, but potentially concealed causal factors. ### Application of FSM in Nervous System Disorders FSM also has significant potential in neurological applications. A notable example involves the treatment of essential tremor, typically tied to basal ganglia function. Here, frequencies such as 81 and 988 come into play, aiming to balance secretions within the basal ganglia. Complementation with nutritional support for dopamine synthesis, including tyrosine and phenylalanine, is recommended. Furthermore, managing post-viral inflammation through the vagus nerve to modulate systemic immune responses demonstrates FSM's versatility and profound potential. Recognizing the interplay between respiratory infections and subsequent systemic inflammation redefines treatment strategies for persistently inflamed joints. ### Practical Advice for Practitioners For practitioners venturing into FSM application, it is crucial to continuously integrate patient feedback and observe both noticeable and subtle changes during the treatment process. Sustained professional development through courses and advanced study helps fine-tune these practices, ultimately leading to greater success rates and patient satisfaction. FSM represents a unique therapeutic tool that extends beyond routine treatment modalities. By refining FSM application approaches, practitioners can ensure patients receive comprehensive care that addresses root causes, not just symptoms. While the application of FSM in clinical settings requires diligence and adherence to safety standards, its potential in elevating patient outcomes makes it an indispensable method in modern integrative medicine.

In this episode, the two souls at the center of the new tremor classification join the MDS Podcast to discuss what essential tremor is. Listen as Prof. Kailash Bhatia and Prof. Günther Deuschl walk you through their clinical methods and future outlook on essential tremor. Do they agree? Disagree?

Title: Staged Focused Ultrasound vs. DBS for Essential Tremor Guest Faculty: G. Rees Cosgrove, MD Hosts: Rushna Ali, MD and Seth F. Oliveria, MD PhD We welcome Dr. Rees Cosgrove to discuss his extensive experience with focused ultrasound and how this compares to deep brain stimulation. We review differences in patient experience and outcome between these two procedures and how to navigate the surge in popularity of FUS when counseling patients of their options.

Dr. Anna Latorre is interviewed by Dr. Sara Schaefer about her study exploring the role of transcutaneous spinal cord simulation for suppression of postural tremor in essential tremor, including the potential pathophysiological mechanisms and implications for therapeutic use. Journal CME is available until October 21, 2025 Read the article.

Dr. Sara Schaefer interviews Dr. Roberto Erro on the phenotypic characteristics of essential tremor, essential tremor with soft dystonic signs, and tremor combined with dystonia through analysis of The Italian tremor Network (TITAN) data. Read the article.

Essential tremor is a common movement disorder. Author Binit B. Shah, MD, of the University of Virginia joins JAMA Deputy Editor Christopher C. Muth, MD, to discuss the diagnostic evaluation and treatment of essential tremor, including pharmacological, nonpharmacological, and surgical treatments. Related Content: Essential Tremor

Dr. Halley Alexander discusses the Neurology Today article, "Prospective Study Presents Longitudinal Trajectory of Cognitive Impairment in Patients With Essential Tremor" by Susan Kreimer, available in the June 20th issue of Neurology Today or at neurologytoday.com.  Show reference:  https://journals.lww.com/neurotodayonline/fulltext/2024/06200/prospective_study_presents_longitudinal_trajectory.2.aspx This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.

Marcio Souza, President and CEO of Praxis Precision Medicines, discusses the challenges in treating central nervous system disorders and is focused on developing life-altering treatments for patients with essential tremor.  Current treatments for epilepsy are often broad-based and not specific to the underlying cause of the disease. Praxis is using insights about genetic epilepsy to understand the underlying imbalances in the brain and develop a precision medicine approach to improve movement disorders.   Marcio explains, "For example, we have four clinical programs right now, four different molecules in the clinic, and many more to come in the future, but four at this given point in time. And one of them is for a very common movement disorder called the essential tremor, which is very common, about 2% of the US population develop this condition. And there is no real understanding of where it comes from. Incredibly debilitating for all the people living with essential tremor. But when you take a step back, and you look into the network, it overlaps with a lot of our understanding of epilepsy." "Other times, we just start in epilepsy, and we end in epilepsy. And I think that's good as well because there is a huge need for better drugs in epilepsy as well. So we're using that as a gateway to either better drugs for epilepsy or new drugs in the case of certain types of epilepsy that don't have any drugs or any treatment available at all. Or to branch out and really understand more mechanistically how to help other diseases. And we think it's only the beginning. There's a lot more to be done there." #PraxisMedicines #EssentialTremor #NeurologicalDiseases #MovementDisorder #FirstinClassMechanism #AtHomeTrial praxismedicines.com Download the transcript here  

Marcio Souza, President and CEO of Praxis Precision Medicines, discusses the challenges in treating central nervous system disorders and is focused on developing life-altering treatments for patients with essential tremor.  Current treatments for epilepsy are often broad-based and not specific to the underlying cause of the disease. Praxis is using insights about genetic epilepsy to understand the underlying imbalances in the brain and develop a precision medicine approach to improve movement disorders.   Marcio explains, "For example, we have four clinical programs right now, four different molecules in the clinic, and many more to come in the future, but four at this given point in time. And one of them is for a very common movement disorder called the essential tremor, which is very common, about 2% of the US population develop this condition. And there is no real understanding of where it comes from. Incredibly debilitating for all the people living with essential tremor. But when you take a step back, and you look into the network, it overlaps with a lot of our understanding of epilepsy." "Other times, we just start in epilepsy, and we end in epilepsy. And I think that's good as well because there is a huge need for better drugs in epilepsy as well. So we're using that as a gateway to either better drugs for epilepsy or new drugs in the case of certain types of epilepsy that don't have any drugs or any treatment available at all. Or to branch out and really understand more mechanistically how to help other diseases. And we think it's only the beginning. There's a lot more to be done there." #PraxisMedicines #EssentialTremor #NeurologicalDiseases #MovementDisorder #FirstinClassMechanism #AtHomeTrial praxismedicines.com Listen to the podcast here  

The presence of a tremor has, in the past, delayed efforts of pilots to become medically certified.  Use of CACI criteria now streamlines the process.  In this episode, we review what is required and touch base on the new FAA reauthorization bill that was signed into law last week.

Fundraising efforts are underway to help give a Clare man back the quality of life he was once used to. Eamon McCormack, originally from Shannon, but now living in Sixmilebridge, was diagnosed with an Essential Tremor, a neurological movement disorder. On Tuesday's Morning Focus Alan Morrissey was joined by Barbara McCormack, organiser of the fundraiser, to help Eamon receive Deep Brain Simulation (DBS) Surgery. To donate, visit: https://www.gofundme.com/f/eamon-mccormack-needs-dbs-surgery?qid=c04b30dfe9e9716f92b792eeaa7e0873

Essential tremor is the most common movement disorder in humans, and its causes are among the most mysterious. It's a neurological condition that causes involuntary shaking. It can begin in one's 20s or 30s, or much later in life. Dr. Natalie Diaz treats essential tremors. Its origins may be unknown, but there are treatments. The first step is to talk to your doctor to rule out other forms of tremor because there are many.

This episode covers benign essential tremor.Written notes can be found at https://zerotofinals.com/medicine/neurology/essentialtremor/ or in the neurology section of the 2nd edition of the Zero to Finals medicine book.The audio in the episode was expertly edited by Harry Watchman.

Essential tremor is a common neurological disorder characterized by involuntary rhythmic shaking, typically in the hands, although it can affect other parts of the body as well. This condition is often hereditary and may worsen with stress or intentional movements. While essential tremor is generally not associated with serious underlying health issues, it can significantly impact an individual's quality of life and may be managed with medication or other treatments to reduce the tremors.

Please Subscribe and Review: Apple Podcasts | RSS Submit your questions for the podcast here News Topic: Salt & Blood Pressure: How Shady Science Sold America a Lie Show Notes: Huberman Lab: What alcohol does to your body, brain and health Questions:    Time to Rethink Alcohol Karen writes: Love you guys!! I would appreciate your take on the effect of alcohol on the body. I am a health coach and I am trying to get as many perspectives as possible so I can offer knowledge to the clients who ask, about the pros and cons of the nightly glass(es) of wine, or the occasional weekend over indulgence. It seems that the deeper I dig on the subject, the more I feel we as a society need to educate ourselves about the potential impact that alcohol can have on our health rather than just look at it as a social acceptance or a “good source of resveratrol”. Please feel free to take a deep dive into the industry as well and a possible comparison to the tobacco industry and the lies that were being told regarding smoking. Are we being told the truth about the effects of alcohol on our body? Please know that your podcast is very much appreciated and I look forward to hearing what is going on in the Wolf household. (Team Home Schooling!!) Thank you for your time. Karen Cauliflower ear and BJJ Kristi writes: Hi Robb and Nicki, Have you found cauliflower ear to be something to worry about in BJJ? I worry about it more as a woman, so I'm curious especially if Nicki has ever thought about it. Do you see a lot of people in classes developing it? Do you do anything like putting binder clips on your ears to prevent it? Thanks, and I appreciate all you both do.   Essential Tremor and GABA connection?    Drew writes: Because I haven't seen a response on the podcast yet re: the potential connection between ET's and a GABA deficiency, I was curious what your thoughts were on that deal. I got diagnosed with ET's about 18 months ago and noticed that my sleep has also been inconsistent in that time. I assumed it was mostly lifestyle (stressful job, two special needs kids, etc), but started to wonder how the sleep inconsistency and ET's could be connected. I know it's a bit of a correlation/causation deal, but based on Doc Parsley's work on sleep and this study (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108714/), I'm curious what your thoughts are on the subject and if you've had any more luck in piecing this whole thing together. If it helps, been Paleo for a more than a decade, and recently leaned into more of Paul Saladino's stuff, especially adding the fruit & honey after jits, which I've been training for 2-3 days a week for about 8 months. I too notice a bit uptick in the ET severity after more than 2 cups of coffee, which is pretty rare nowadays since cutting back the caffeine helps so much with sleep and the ET severity. Thanks, Drew   Sponsor: The Healthy Rebellion Radio is sponsored by our electrolyte company, LMNT. Proper hydration is more than just drinking water. You need electrolytes too! Check out The Healthy Rebellion Radio sponsor LMNT for grab-and-go electrolyte packets to keep you at your peak! They give you all the electrolytes want, none of the stuff you don't. Click here to get your LMNT electrolytes Transcript: Coming soon...    

MedLink Neurology Podcast is delighted to feature selected episodes from BrainWaves, courtesy of James E Siegler MD, its originator and host. BrainWaves is an academic audio podcast whose mission is to educate medical providers through clinical cases and topical reviews in neurology, medicine, and the humanities, and episodes originally aired from 2016 to 2021.Originally released: July 18, 2017Once heralded as "benign" essential tremor, this movement disorder is anything but. And you can see this when you talk with your neurology patients about the difficulties they encounter with dressing, eating, and even speaking--not to mention the social stigmata and cognitive dysfunction. In this BrainWaves episode, we start by describing the fundamentals of tremor and move on to the clinical features, pharmacology, and prognosis of essential tremor. BrainWaves podcasts and online content are intended for medical education only and should not be used to guide medical decision-making in routine clinical practice. Any cases discussed in this episode are fictional and do not contain any patient health-identifying information. REFERENCES Deuschl G, Raethjen J, Hellriegel H, Elble R. Treatment of patients with essential tremor. Lancet Neurol 2011;10(2):148-61. PMID 21256454Louis ED. Diagnosis and management of tremor. Continuum (Minneap Minn) 2016;22(4 Movement Disorders):1143-58. PMID 27495202Sandvik U, Koskinen LO, Lundquist A, Blomstedt P. Thalamic and subthalamic deep brain stimulation for essential tremor: where is the optimal target? Neurosurgery 2012;70(4):840-5; discussion 845-6. Erratum in: Neurosurgery 2021;88(3):707. PMID 22426044Zesiewicz TA, Elble R, Louis ED, et al. Practice parameter: therapies for essential tremor: report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2005;64(12):2008-20. PMID 15972843 We believe that the principles expressed or implied in the podcast remain valid, but certain details may be superseded by evolving knowledge since the episode's original release date.

#BRNAM #1504 | Focused Ultrasound as a treatment for Essential tremor | Stephen Harward II, MD, PhD, Duke Neurosurgery   | #Tunein: broadcastretirementnetwork.com #JustTheFacts

Host Mike Moore & Renee Ryan discuss Cala Health's kIQ™ wearable technology. kIQ™ is the only FDA-cleared, wearable device that delivers effective therapy for action hand tremors in people with essential tremors and Parkinson's disease. kIQ, pronounced “kick,” stands for Kinetic [movement] + IQ [smart] Resources & Links Mike Moore https://www.linkedin.com/in/michaeljeffreymoore/ https://www.linkedin.com/company/thebleedingedgeofdigitalhealth/

Murray Bocian, 76, was prone to spilling things: His hands were so shaky that he had to begin using a child's sippy cup. Murray was battling a condition called essential tremor, and it was impacting many aspects of his daily life. A nervous system disorder, essential tremor starts in the brain and triggers shakiness in the extremities, most often the hands. For most of the 10 million Americans living with essential tremor, lifestyle changes and medications can help manage symptoms. But when the condition interferes with daily activities as it was Murray, more targeted therapies are needed. For decades, the solution has been to open the skull and operate on the brain. Now there's a new incision-less procedure called high-intensity focused ultrasound — HIFU — which can be done with an MRI scanner in a single two-hour outpatient session. And the effects are immediate. On this episode, we hear from Murray and speak with his surgeon, Albert Fenoy, MD, who explains how this new procedure works, who is a candidate, and how HIFU is improving the quality of life for patients living with essential tremor.

Tremors (Episode 90, To Your Health with Dr. Jim Morrow) On this episode of To Your Health, Dr. Jim Morrow covers tremors, the difference between benign essential tremors and Parkinson’s Disease, how they are diagnosed, potential causes, what the doctor might do for treatment, and much more. To Your Health is brought to you by […] The post Tremors appeared first on Business RadioX ®.

Listen as Dr. London Smith (.com) and his producer Cameron discuss Parkinsonism with special guest Dino Withandre (Frankie G of WizWorldLive).  Sponsored by Caldera + Lab (use code "jockdoc" to get 20% off!). Not so boring! https://calderalab.com/pages/podcast-special-offer?show=Jock+Doc&utm_medium=podcast&utm_source=JocDoc https://www.patreon.com/join/jockdocpodcast Hosts: London Smith, Cameron Clark. Guest: Frankie G. Produced by: Dylan Walker Created by: London Smith

In this episode, host Dr. Jacob Fleming interviews one of his attendings Dr. Bhavya Shah about the remarkable features of focused ultrasound technology and its applications. They discuss its dynamic nature, allowing for a wide range of applications. --- SHOW NOTES Dr. Bhavya Shah is a neuroradiologist at UT Southwestern in Dallas, TX and the director of their transcranial-focused ultrasound lab. While in residency at Boston MIT, he studied the radiology applications for nerve regeneration and expanded his scope of practice during his fellowship at Stanford. Dr. Bhavya Shah explains the use of low intensity focused ultrasound (LIFU) and high intensity focused ultrasound (HIFU), particularly in the context of movement disorders including essential tremor and Parkinson's disease. LIFU is used to identify the appropriate targets in the brain in relation to the disease and may be used to alter how neurons behave. In contrast, high intensity focused ultrasound (HIFU) is utilized to ablate and destroy tissues typically after the localization of the intended treatment area. Dr. Shah developed a way to identify targets in the brain for treatment with focused ultrasound with the use of four-tract tractography in cadavers. Using this technology, the brain can be thinly sliced into sections which could then be registered off an MRI back to the path using block face photography, allowing the identification of white matter tracts that enter and leave the thalamus. With these tracts identified, neuroradiologists can first stimulate the localized area with LIFU to confirm the location, then ablate using HIFU. The procedure lasts approximately 30-45 minutes as the patient remains awake. Remarkably, patients with essential tremor usually experience benefit immediately following the procedure as patients with Parkinson's have symptom improvement within days to weeks. After two hours of observation, patients are discharged assuming no side effects. Side effects are uncommon but can include numbness and tingling around the mouth or fingertips as well as muscle weakness. Beyond its use for movement disorders, the adaptable nature of focused ultrasound technology shows promise for a broad range of applications, particularly for the use of neuropsychiatric conditions. Dr. Shah offers the potential for the use of HIFU as a wearable device that delivers constant stimulation modulated by biofeedback, potentially eliminating the need for MRI for the procedure. Dr. Shah and Dr. Fleming end the discussion with how radiology has evolved over the years and the importance of keeping an open mind working in a multidisciplinary team. They emphasize the gravity of patient engagement and the central goal of medicine and improving the standard of care should always be aimed at benefiting the patient. --- RESOURCES MRI–Guided Focused Ultrasound Thalamotomy for Essential Tremor: https://thejns.org/view/journals/j-neurosurg/138/4/article-p1028.xml Trial of Globus Pallidus Focused Ultrasound Ablation in Parkinson's Disease: https://www.nejm.org/doi/10.1056/NEJMoa2202721 Long-term effects of bilateral subthalamic nucleus deep brain stimulation on gait disorders in Parkinson's disease: a clinical-instrumental study https://pubmed.ncbi.nlm.nih.gov/37208527/ Magnetic Resonance Image Guided Focused Ultrasound Thalamotomy. A Single Center Experience With 160 Procedures: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894664/

In this episode, host Dr. Jacob Fleming interviews one of his attendings Dr. Bhavya Shah about the remarkable features of focused ultrasound technology and its applications. They discuss its dynamic nature, allowing for a wide range of applications. --- SHOW NOTES Dr. Bhavya Shah is a neuroradiologist at UT Southwestern in Dallas, TX and the director of their transcranial-focused ultrasound lab. While in residency at Boston MIT, he studied the radiology applications for nerve regeneration and expanded his scope of practice during his fellowship at Stanford. Dr. Bhavya Shah explains the use of low intensity focused ultrasound (LIFU) and high intensity focused ultrasound (HIFU), particularly in the context of movement disorders including essential tremor and Parkinson's disease. LIFU is used to identify the appropriate targets in the brain in relation to the disease and may be used to alter how neurons behave. In contrast, high intensity focused ultrasound (HIFU) is utilized to ablate and destroy tissues typically after the localization of the intended treatment area. Dr. Shah developed a way to identify targets in the brain for treatment with focused ultrasound with the use of four-tract tractography in cadavers. Using this technology, the brain can be thinly sliced into sections which could then be registered off an MRI back to the path using block face photography, allowing the identification of white matter tracts that enter and leave the thalamus. With these tracts identified, neuroradiologists can first stimulate the localized area with LIFU to confirm the location, then ablate using HIFU. The procedure lasts approximately 30-45 minutes as the patient remains awake. Remarkably, patients with essential tremor usually experience benefit immediately following the procedure as patients with Parkinson's have symptom improvement within days to weeks. After two hours of observation, patients are discharged assuming no side effects. Side effects are uncommon but can include numbness and tingling around the mouth or fingertips as well as muscle weakness. Beyond its use for movement disorders, the adaptable nature of focused ultrasound technology shows promise for a broad range of applications, particularly for the use of neuropsychiatric conditions. Dr. Shah offers the potential for the use of HIFU as a wearable device that delivers constant stimulation modulated by biofeedback, potentially eliminating the need for MRI for the procedure. Dr. Shah and Dr. Fleming end the discussion with how radiology has evolved over the years and the importance of keeping an open mind working in a multidisciplinary team. They emphasize the gravity of patient engagement and the central goal of medicine and improving the standard of care should always be aimed at benefiting the patient. --- RESOURCES MRI–Guided Focused Ultrasound Thalamotomy for Essential Tremor: https://thejns.org/view/journals/j-neurosurg/138/4/article-p1028.xml Trial of Globus Pallidus Focused Ultrasound Ablation in Parkinson's Disease: https://www.nejm.org/doi/10.1056/NEJMoa2202721 Long-term effects of bilateral subthalamic nucleus deep brain stimulation on gait disorders in Parkinson's disease: a clinical-instrumental study https://pubmed.ncbi.nlm.nih.gov/37208527/ Magnetic Resonance Image Guided Focused Ultrasound Thalamotomy. A Single Center Experience With 160 Procedures: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894664/

Long-time friend and Austin bassist Cindy Toth (The Reivers, Flying Saucers) discusses her Essential Tremor. Essential listening! Support Friends WIth Deficits: https://www.patreon.com/friendswithdeficits      

Recorded for release W/C 3rd April 2023 This week Scott Bird lets us know about the year ahead on stage at the Wolverhampton Grand, Beth Berwick Lowe shares news of the Starstruck Theatre Production of The Addams Family, we hear about the debut novel from  Wayne M Bailey, David Domony share some gardening tips and we find out about the condition Essential Tremor.

Dr. Melita Petrossian is a neurologist who specializes in movement disorders. When most people hear that term, they think of Parkinson's disease. But Dr. Petrossian sees a number of patients with what's known as essential tremor, a condition that's often mistaken for Parkinson's. It affects eight million Americans, far more than suffer from Parkinson's. The brain has “tremor generators” that help us move. The tremor is natural, but the cerebellum smooths it out, like the steady cam features on our phones, so we don't shake. Babies often jerk their limbs because the cerebellum hasn't mastered the task. In cases of essential tremor, the cerebellum loses the ability to do that work. Listen to this episode to find out why the condition is called “essential” and how Dr. Petrossian helps alleviate the symptoms for people who have it.

On this episode, Jimbo talks about his experience with essential tremor, a progressive neurological disorder that he was born with.  He also chats with Patrick McCartney, executive director of the International Essential Tremors Foundation and gets plenty of eye-opening information about the disorder, its causes, treatments, and more.  Visit essentialtremor.org to learn more.

Lothar Krinke is the CEO and Board Member of Newronika which is an adaptive Deep Brain Stimulator company looking to improve patient outcomes in things like Parkinson's and Essential Tremor. ***This podcast is sponsored by Iris Biomedical, check out their Neurotech Startup Services here*** Top 3 Takeaways: "the one thing we do need to address is really the cost. The cost driver of Deep Brain Stimulation isn't the manufacturing of the system. Now, that's not cheap either it's certainly less than $10,000. How expensive is brain surgery, particularly functional brain surgery? How expensive is it to have all the pre-operation preparation? So I think the field needs to think about how we can lower the cost of Deep Brain Stimulation to make it available to not hundreds of thousands of patients, but literally millions of patients." "I don't think AI or even machine learning has been sufficiently applied in our space. People do it and they talk about it, but if you look at other fields, even EEG, use of AI or machine learning are much more penetrated." "In my mind it is almost unconscionable that only 15% of patients that could benefit from Parkinsons, from DBS do. So somehow we need to have a battle cry. We need to have the responsibility to make this therapy available to more people. And the way to do that is less invasive more automation and lower cost" 0:45 Do you want to introduce yourself better than I just did? 2:15 "Why is Deep Brain Simulation so exciting for you?" 3:15 "Can explain what Deep Brain Stimulation is and what it's a treatment for?" 5:30 "How did you get into the field?" 6:30 Iris Biomedical ad sponsorship 7:15 You thought earlier that DBS was too invasive but now changed your mind, why? 8:15 What are the biggest impediments to DBS? 12:15 Why is the Newronika DBS better than the alternatives? 14:30 Why is adaptive DBS better? 16:30 "What are some of the biggest challenges right now at Newronika?" 20:30 You are in Minneapolis, West Virginia, and Milan, how are you able to travel so much? 21:30 "Why aren't you in Gainesville? I was surprised how big the DBS field is here." 22:15 "For people starting out in the field, do you have any advice?" 25:30 " What's a big mistake or wrong direction that you see researchers or people on your field going down?" 27:45 "Could you explain the beta and gamma waves?" 32:45 "Is there anything that we didn't talk about that you wanted to mention?"

Dr. Vikram Karnik discusses the surgical management of essential tremor. This podcast is sponsored by argenx. Visit www.vyvgarthcp.com for more information.  

In this episode, we review the high-yield topic of Essential Tremor from the Neurology section. Follow Medbullets on social media: Facebook: www.facebook.com/medbullets Instagram: www.instagram.com/medbulletsofficial Twitter: www.twitter.com/medbullets

Deep Brain Stimulation (DBS), an exciting treatment option for people with Parkinson's Disease, Essential Tremor and Dystonia.We are the only center in Ventura County, and one of the few in Southern California to offer this treatment.While the selection process is thorough, we encourage anyone with one of these conditions to come in and discuss this option. Boiled down, when taking more pills is not the answer, come in and learn more. We expect to improve a patient's symptoms while at the same cutting meds in half--and sometimes more!

Huberman Lab Podcast Notes Key Takeaways Episodic therapy via deep brain stimulation delivered at the right time and only as needed at that time may be useful in treating obesity, addiction, and OCD to interrupt circuit dysfunctionObesity is a phenotype often reflective of behavior – there's a compulsion to overeat despite the riskDevelopment of eating disorders: (1) we've become a food-focused society – we're really not meant to have constant stimulation of food; (2) there's high fructose corn syrup in almost everything – processed foods rewire our circuitry to seek more; (3) recurring stressful event or life; (4) patients are embarrassed because society frowns on themRight before people participate in binge eating, there's a moment of feeling down or negative affect that they compensate for by binge eating or “loss of control eating”Deep brain stimulation is currently being studied for use in binge eaters by provoking the craving during surgery and identifying the exact area of the nucleus accumbens where cravings occur – then delivering electrical stimulationAnorexia, bulimia, and binge eating are all distortions in relationship to food where reward and habit are disrupted beyond controlSide note discussed: use power lifting and deadlifts specifically (with impeccable form, under supervision of trainer if needed) to profoundly improve strength & posture Read the full notes @ podcastnotes.orgMy guest is Casey Halpern, M.D., Chief of Stereotactic and Functional Neurosurgery and Professor of Neurosurgery at the Perelman School of Medicine at the University of Pennsylvania. Dr. Halpern's research and clinical practice focus on using deep brain stimulation to treat compulsive and movement disorders (e.g., binge eating disorders, bulimia, obsessive-compulsive disorder (OCD) and Parkinson's disease essential tremor, dystonia). We discuss using deep brain stimulation to help patients who suffer from movement and compulsive disorders and applying this treatment to patients afflicted with binge eating. We also explore applications of this technology to other conditions such as OCD, anorexia and tremor, and the future therapeutic directions of the use of non-invasive brain stimulation approaches, including transcranial magnetic stimulation and ultrasound, for the treatment of other psychiatric illnesses and conditions. This episode will interest those curious about the biology of eating, anorexia, bulimia, compulsive thoughts and behaviors, and movement. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman ROKA: https://www.roka.com/huberman Eight Sleep: https://www.eightsleep.com/huberman InsideTracker: https://insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Casey Halpern & Disordered Eating & Brain Stimulation (00:03:18) ROKA, Eight Sleep, InsideTracker (00:07:19) Momentous Supplements (00:08:28) Neurosurgeon's View of the Brain, Neurosurgery Specialization (00:13:05) Deep Brain Stimulation & Other Unexpected Positive Effects (00:17:20) Obsessive Compulsive Disorder (OCD), Prescriptions & Cognitive Therapies (00:25:40) Brain Areas in OCD, Risk, Rewards & Addiction (00:31:11) AG1 (Athletic Greens) (00:32:27) Facial and Vocal Ticks, Stimulants, Stress & Superstition (00:39:28) Nucleus Accumbens, Reward Circuits, Eating Disorders & Obesity (00:47:18) Stimulation of Nucleus Accumbens, Continuous vs. Episodic Stimulation (00:49:49) Binge Eating Disorder & Loss of Control Eating (00:53:02) Developing Binge Eating Disorder: Predisposition, Environment, Stress (01:02:07) Electrodes in Nucleus Accumbens, Identifying “Craving Cells” (01:11:41) Effects of Stimulation, Interrupting Craving, Intermediate Stimulation (01:16:46) Anorexia, Obesity & Compulsions, Potential Treatments for Anorexia (01:23:14) Non-Invasive Brain Stimulation, Transcranial Magnetic Stimulation (01:32:27) MRI-Guided Focused Ultrasound: Tremor, Essential Tremor & Parkinson's (01:36:40) Future of Non-Invasive Brain Stimulation, Epilepsy & Depression (01:41:51) Pre-Behavioral States in Compulsion & Awareness, Mood Provocation (01:48:02) Machine Learning/Artificial Intelligence & Compulsion Predictions (01:53:05) Neurosurgeon Hands, Resistance Training & Deadlifts (01:59:00) “Neurosurgeon Calm,” Quality Time & Prioritization, Neurosurgeon Training (02:09:53) Daily Habits: Sleep, Exercise, Mediation (02:11:59) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook, LinkedIn  Title Card Photo Credit: Mike Blabac Disclaimer

My guest is Casey Halpern, M.D., Chief of Stereotactic and Functional Neurosurgery and Professor of Neurosurgery at the Perelman School of Medicine at the University of Pennsylvania. Dr. Halpern's research and clinical practice focus on using deep brain stimulation to treat compulsive and movement disorders (e.g., binge eating disorders, bulimia, obsessive-compulsive disorder (OCD) and Parkinson's disease essential tremor, dystonia). We discuss using deep brain stimulation to help patients who suffer from movement and compulsive disorders and applying this treatment to patients afflicted with binge eating. We also explore applications of this technology to other conditions such as OCD, anorexia and tremor, and the future therapeutic directions of the use of non-invasive brain stimulation approaches, including transcranial magnetic stimulation and ultrasound, for the treatment of other psychiatric illnesses and conditions. This episode will interest those curious about the biology of eating, anorexia, bulimia, compulsive thoughts and behaviors, and movement. Thank you to our sponsors AG1 (Athletic Greens): https://athleticgreens.com/huberman ROKA: https://www.roka.com/huberman Eight Sleep: https://www.eightsleep.com/huberman InsideTracker: https://insidetracker.com/huberman Supplements from Momentous https://www.livemomentous.com/huberman For the full show notes, visit hubermanlab.com Timestamps (00:00:00) Dr. Casey Halpern & Disordered Eating & Brain Stimulation (00:03:18) ROKA, Eight Sleep, InsideTracker (00:07:19) Momentous Supplements (00:08:28) Neurosurgeon's View of the Brain, Neurosurgery Specialization (00:13:05) Deep Brain Stimulation & Other Unexpected Positive Effects (00:17:20) Obsessive Compulsive Disorder (OCD), Prescriptions & Cognitive Therapies (00:25:40) Brain Areas in OCD, Risk, Rewards & Addiction (00:31:11) AG1 (Athletic Greens) (00:32:27) Facial and Vocal Ticks, Stimulants, Stress & Superstition (00:39:28) Nucleus Accumbens, Reward Circuits, Eating Disorders & Obesity (00:47:18) Stimulation of Nucleus Accumbens, Continuous vs. Episodic Stimulation (00:49:49) Binge Eating Disorder & Loss of Control Eating (00:53:02) Developing Binge Eating Disorder: Predisposition, Environment, Stress (01:02:07) Electrodes in Nucleus Accumbens, Identifying “Craving Cells” (01:11:41) Effects of Stimulation, Interrupting Craving, Intermediate Stimulation (01:16:46) Anorexia, Obesity & Compulsions, Potential Treatments for Anorexia (01:23:14) Non-Invasive Brain Stimulation, Transcranial Magnetic Stimulation (01:32:27) MRI-Guided Focused Ultrasound: Tremor, Essential Tremor & Parkinson's (01:36:40) Future of Non-Invasive Brain Stimulation, Epilepsy & Depression (01:41:51) Pre-Behavioral States in Compulsion & Awareness, Mood Provocation (01:48:02) Machine Learning/Artificial Intelligence & Compulsion Predictions (01:53:05) Neurosurgeon Hands, Resistance Training & Deadlifts (01:59:00) “Neurosurgeon Calm,” Quality Time & Prioritization, Neurosurgeon Training (02:09:53) Daily Habits: Sleep, Exercise, Mediation (02:11:59) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous Supplements, Neural Network Newsletter, Instagram, Twitter, Facebook, LinkedIn  Title Card Photo Credit: Mike Blabac Disclaimer

Make your health an act of rebellion. Join The Healthy Rebellion Please Subscribe and Review: Apple Podcasts | RSS Submit your questions for the podcast here News topic du jour: https://boriquagato.substack.com/p/eu-physics-denial-has-come-home-to Podcast Questions: 1. LASIK [17:19] Mark says: Hi Robb and Nikki, On last week's episode Robb mentioned getting LASIK. I don't think I've heard this mentioned on the podcast before. I'm short-sighted (-4.00), and have long been considering LASIK. But, something about it just makes me feel squeamish. Robb, how much research into the procedure did you have to do before getting comfortable with it? Are there any major thoughts/findings from your research worth sharing? And, you being someone who's active and does BJJ, did you consider LASEK (ek) over LASIK (ik), which I've read is often preferred by military personnel/police/boxers/the like (anything high impact). From an article in The Times (UK): "Unlike the most common form of laser eye surgery, Lasik, the operation used on military personnel, Lasek, does not involve slicing a flap in the cornea because there is a slim chance that a hard blow could dislodge the flap. Boxers, police officers and those with a very active lifestyle are also advised to opt for Lasek." How was your recovery – being able to get back into physical activity? Any and all thoughts that might help me overcome my squeamishness would be much appreciated! Mark 2. Returning to fitness after cancer [29:48] Greg says: Hey Robb and Nikki, I have a friend who has just finished an extensive round of chemo treatments. He wants to know what would be the best way to pursue getting back in shape and getting his health in order post-chemo. Are there any specific things he should focus on in terms of diet and exercise? Thanks for everything you do. 3. Essential Tremors [32:25] Sandy says: I have heard you mention several times on Podcasts that you are finding some relief from your essential tremors with lions mane. I would love to do my own experiment to see if this would help me. What form of lions mane would you suggest? What dosage would you shoot for? How long did it take until you saw some relief? All of the drugs I have tried for my tremors gave me side effects that were worse than the tremors themselves. So I had given up. This is the first time in a long time I have felt hopeful. Thanks for what you do! Sponsor: The Healthy Rebellion Radio is sponsored by our electrolyte company, LMNT. Proper hydration is more than just drinking water. You need electrolytes too! Check out The Healthy Rebellion Radio sponsor LMNT for grab-and-go electrolyte packets to keep you at your peak! They give you all the electrolytes want, none of the stuff you don't. Click here to get your LMNT electrolytes Transcript: You can find the transcript at this episode's blog page https://robbwolf.com/2022/09/16/lasik-fitness-after-cancer-essential-tremor-thrr123/

Welcome to the NeurologyLive® Mind Moments™ podcast. Tune in to hear leaders in neurology sound off on topics that impact your clinical practice. In this episode, we spoke with Rajesh Pahwa, MD, professor of neurology, and director, Parkinson's Disease and Movement Disorder Center, University of Kansas Medical Center. He spoke about the current state of treatment for essential tremor, including the therapeutic and surgical options for this population, and shared his perspective on the latest advances in clinical care and diagnosis, the role of the patient-physician relationship, and the research into the disease's underlying processes. Episode Breakdown: 1:25 – Overview of the current state of essential tremor care 7:05 – Changes in thinking about essential tremor 9:05 – Potential in the therapeutics pipeline 10:45 – Advances in the understanding of essential tremor 12:40 – Neurology News Minute 15:30 – The role of shared decision-making in care 18:50 – Surgical options for essential tremor treatment 22:00 – Education and diagnosis outside of movement specialists 24:00 – Advances on the horizon Check out Medical World News' Second Opinion only at medicalworldnews.com The stories featured in this week's Neurology News Minute, which will give you quick updates on the following developments in neurology, are further detailed here: Biogen, Alectos Announce Licensing Agreement for Parkinson Disease GBA2 Inhibitor AL01811 FDA Advisory Committee Agrees to Reconvene for Decision on ALS Treatment AMX0035 FDA Accepts BLA for Lecanemab in Alzheimer Disease, Sets PDUFA Date for January 2023 FDA Places Clinical Hold on Phase 2/3 ReMEDy2 Trial of DM199 in Acute Ischemic Stroke Thanks for listening to the NeurologyLive® Mind Moments™ podcast. To support the show, be sure to rate, review, and subscribe wherever you listen to podcasts. For more neurology news and expert-driven content, visit neurologylive.com.

TELL EVERYONE - New mom chat - Kali's article and twitter      - https://www.insider.com/my-child-diagnosed-rare-genetic-condition-syngap1-2022-6       - https://twitter.com/WorthKali - Tavillas: https://syngap.fund/susan (6/22/15)   CHECK OUT THIS CONFERENCE: https://syngap.fund/treat   DRUG CO NEWS - Anglemans and Ionis! https://www.prnewswire.com/news-releases/ionis-treatment-for-angelman-syndrome-receives-orphan-drug-and-rare-pediatric-disease-designations-from-us-fda-301566169.html  - Praxis update: At the end, scroll down.    CIITIZEN - Webinar was awesome https://syngap.fund/virginie - Sign up! https://www.ciitizen.com/syngap1/   PROBABLY GENETIC IS WORKING! - Assessment:  syngap.fund/maybe - https://symptom-checker.probablygenetic.com/syngap/  - Webinar: https://syngap.fund/PG  - Sponsored testing with Mahzi! https://mahzi.com/    REMEMBER NOT TO MISS  - June 2022 https://mailchi.mp/syngapresearchfund.org/june22   - Sign up for the EF Panel: https://bit.ly/efmen      FUNDRAISERS - MDBR: Join us and secure $30k matching funds https://syngap.fund/SRFMDBR22   - MICE: Help us Make 2!  https://syngap.fund/2mice    EVENTS - June 25 in DFW - Join us for a family meeting and hear from Dr. Perry.  Link soon. - September 12-14 in San Diego - #GlobalGenes Meeting.  Link soon. - October 8 in NJ - Caren Leib Gala https://www.syngapresearchfund.org/get-involved/fundraising/caren-leib-gala  - October 8 in SC - Scramble for SYNGAP https://www.syngapresearchfund.org/get-involved/fundraising/scramble-for-syngap   - November 12 in GA - Sparks of Hope Gala https://syngap.fund/soiree  - December 1 in TN - Syngap Science Meeting - https://syngap.fund/treat    This is a podcast: subscribe to and rate this 10 minute #podcast #SYNGAP10 here https://www.syngapresearchfund.org/syngap10-podcast   Apple podcasts: https://podcasts.apple.com/us/podcast/syngap10-weekly-10-minute-updates-on-syngap1-video/id1560389818    Episode 64 of #Syngap10 - June 14, 2022 #F78A1 #Syngap #epilepsy #autism #intellectualdisability #id #anxiety #raredisease #epilepsyawareness #autismawareness #rarediseaseresearch #SynGAPResearchFund #CareAboutRare #PatientAdvocacy #GCchat #Neurology #GlobalCollaboration #EpilepsyFoundation #Praxis #ProbablyGenetic #Mahzi   Copy from letter from Praxis: Monday morning, June 6th, we published an 8K filing announcing news involving multiple programs at Praxis Precision Medicines. One of these announcements pertained to the FDA's clinical hold on our recent IND filing for PRAX-222 in SCN2A, so we wanted to share further context for it. On May 25, 2022, the Company received a communication from the U.S. Food and Drug Administration (the “FDA”) providing additional information on the clinical hold placed on the Company's Investigational New Drug application (the “IND”) for the study of PRAX-222, an antisense oligonucleotide, for the treatment of patients with SCN2A gain-of-function mutations. The communication indicated that our IND could be cleared once we submit additional documentation related to the preclinical non-human primate toxicology study that supports the proposed starting dose in the clinical study. We're requesting a Type A meeting with the FDA to confirm the study design and further clarify the requirements for dose escalation beyond the starting dose. This surely will leave our SCN2A community with questions about the timing of our path forward. While the protocol and the discussions being held with the FDA remain confidential, we will do our best to maintain transparency and responsiveness throughout the process.     We continue to be fully committed to advancing PRAX-222 to clinical study. We also want to restate that this news is specific to PRAX-222, without impact on our PRAX-562 program for SCN2A, SCN8A and TSC. In Monday's press release, we reiterated our focus on driving toward proof of concept for PRAX-562. We'll provide further updates on PRAX-562 as we approach major milestones on this path. In addition, our other programs in PCDH19 and SYNGAP1 remain on-track.     Beyond epilepsy, Monday's 8K filing announced significant news pertaining to our Aria study of PRAX-114 in Major Depressive Disorder (MDD). It is with great regret that we announce the failure of the Aria Study, a study to determine the efficacy of a GABBA PAM extrasynaptic preference medicine to achieve fast-acting, lasting reduction of symptoms of MDD. After reviewing the data and our operational controls and observing failure to achieve our primary endpoint, we determined that PRAX-114 was indeed safe but not efficacious, and no further research and development of PRAX-114 is warranted. This conclusion has a negative impact on the study of PRAX-114 to treat Post-Traumatic Stress Disorder and Essential Tremor. This is a difficult decision for the Praxis team; but our commitment and capacity to researching and developing genetic insight-based treatments for people living with disorders of the CNS is in no way diminished.

What are essential tremors? In this program, Dr. Doris Wang explains that essential tremors are rhythmic, involuntary movements of the head, voice or extremities. Common neurological diseases associated with tremors are cerebellar degeneration, Parkinson's disease, and thalamic hemorrhage. Yang discusses how tremors are diagnosed and treated. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 37859]

What are essential tremors? In this program, Dr. Doris Wang explains that essential tremors are rhythmic, involuntary movements of the head, voice or extremities. Common neurological diseases associated with tremors are cerebellar degeneration, Parkinson's disease, and thalamic hemorrhage. Yang discusses how tremors are diagnosed and treated. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 37859]

What are essential tremors? In this program, Dr. Doris Wang explains that essential tremors are rhythmic, involuntary movements of the head, voice or extremities. Common neurological diseases associated with tremors are cerebellar degeneration, Parkinson's disease, and thalamic hemorrhage. Yang discusses how tremors are diagnosed and treated. Series: "Mini Medical School for the Public" [Health and Medicine] [Show ID: 37859]

Essential Tremor has always been treated by medication that's not guaranteed to work, or brain surgery. A doctor explains the new, non-invasive treatment that can help those suffering with ET. Learn more at: https://radiohealthjournal.org/non-invasive-treatment-for-essential-tremor/

For patients with essential tremor (ET), the uncontrollable shaking of the hand, head, and voice can interfere with nearly all aspects of life. A new outpatient procedure that uses high-intensity ultrasound has been shown to significantly reduce tremor symptoms for years in most patients. Shervin Rahimpour, MD, assistant professor of neurosurgery, explains how the procedure works and how effective it can be to help essential tremor patients.

Prof. Andres Lozano shares the results of the phase 2 clinical trial showing safety and feasibility of the staged bilateral MR-guided focus ultrasound thalamotomy in 10 patients. Read the article.

Susan Marks is a certified family nurse practitioner who focuses on the medical use of cannabis. She's also a daily user for essential tremor. She talks with host Seán Collins about what she calls the treasure trove of medicinal benefits the cannabinoids in marijuana represent. .Susan Marks, CFNPWebsite  |  Twitter  |  Facebook.American Cannabis Nurses AssociationDoctors for Cannabis RegulationMedical Cannabis Laws by State   (National Conference of State Legislatures)WeedMap's directory of dispensaries.------------------------------------------.Are you a healthcare professional with questions about the best practices for using social media? We're interested in hearing from you.  Leave a voicemail message at +1 424-212-5436 or drop us an email at HearMeNowStories@providence.org.