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Increasing numbers of people are surviving stroke but with motor impairments that can contribute substantially to long-term disability. Transcranial direct current stimulation has shown promise in reducing motor impairment when combined with rehabilitation therapy. Sarah Passey talks to Wayne Feng (Duke University School of Medicine, Durham, NC, USA) about his latest trial, TRANSPORT2, which assesses transcranial direct current stimulation in combination with modified constraint-induced movement therapy.Read the full article:https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00044-4/fulltext?dgcid=buzzsprout_tlv_podcast_16-04-25_laneurContinue this conversation on social!Follow us today at...https://thelancet.bsky.social/https://instagram.com/thelancetgrouphttps://facebook.com/thelancetmedicaljournalhttps://linkedIn.com/company/the-lancethttps://youtube.com/thelancettv
Lifting the Cloud: Transcranial Magnetic Stimulation and the Treatment of Major DepressionThis episode provides an in-depth exploration of Transcranial Magnetic Stimulation (TMS) and its impact on psychiatric disorders. TMS has demonstrated effectiveness in numerous clinical trials and serves as a valuable adjunct to traditional therapy. Designed for clinicians and mental health professionals and those they serve, this podcast offers insights into:Identifying appropriate patient populations for TMS therapy. Understanding the TMS treatment process from start to finish. Exploring the role of neuromodulation in reshaping brain function for long-term improvement. Reviewing clinical outcome data supporting TMS in the treatment of major depressive disorder. Gain a deeper understanding of how TMS and neuromodulation techniques are advancing the field of functional neuropsychiatry and providing new hope for patients. Objectives: Identify appropriate patient populations for Transcranial Magnetic Stimulation (TMS) treatment of psychiatric disorders.Describe the treatment process of Transcranial Magnetic Stimulation. Describe possible adverse events associated with Transcranial Magnetic Stimulation.Explain how neuromodulation techniques impact long-term changes in brain network functioning.Discuss clinical outcome data for Transcranial Magnetic Stimulation treatment. Guests: Dr. Henry Emerle, MDDr. Rich Whitaker, PhDBios: Dr. Rich Whitaker began his career in the Quad Cities in 1994 as a doctoral intern at the historic Marriage and Family Counseling Service in Rock Island, Illinois as part of his Ph.D. in Marriage and Family Therapy from Brigham Young University. Since that pivotal year, Dr. Whitaker has pursued a career in community mental health, providing services, supervision, and executive administration at community mental health centers in Grand Island, Nebraska (9 years as COO) and Jasper, Indiana (12 years as CFO). Since January 2017, Rich has served as the CEO of Vera French Community Mental Health Center in Davenport, Iowa. In addition to serving as a Director of Region 7 on the Board of the National Council for Mental Wellbeing, Dr. Whitaker also serves as a Government Relations Committee member for the Iowa Association of Community Providers, as a Board member of Churches United in the Quad Cities, and as a member of the Eastern Iowa MHDS Regional Advisory Committee.Rich and Miriam are the parents of 3 daughters and one son and the proud grandparents of a growing number of highly intelligent and multi-talented grandchildren. In his spare time, Rich enjoys family time, all types of sports and exercise, singing with the Quad City Singers, and service in the church and community.Henry Emerle, MD completed his medical school training at the University of Illinois College of Medicine at Urbana-Champaign, IL. He completed Psychiatry Residency training as well as Geriatric Psychiatry Fellowship training at the University of Michigan in Ann Arbor, MI. He is the Medical Director at Vera French Community Mental Health Center. He enjoys spending time with his family exploring the many charming towns in Iowa along the Mississippi River. References: Cash RFH, Cocchi L, Lv J, Fitzgerald PB, Zalesky A. Functional Magnetic Resonance Imaging–Guided Personalization of Transcranial Magnetic Stimulation Treatment for Depression. JAMA Psychiatry. 2021;78(3):337–339. doi:10.1001/jamapsychiatry.2020.3794Jannati, A., Oberman, L.M., Rotenberg, A. et al. Assessing the mechanisms of brain plasticity by transcranial magnetic stimulation. Neuropsychopharmacol. 48, 191–208 (2023). https://doi.org/10.1038/s41386-022-01453-8Pitcher, D., Parkin, B., & Walsh, V. (2021). Transcranial magnetic stimulation and the understanding of behavior. Annual Review of Psychology, 72, 97-121. https://doi.org/10.1146/annurev-psych-081120-013144Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Study (n.d.) https://www.nimh.nih.gov/funding/clinical-research/practical/stard
Suzanne Jessee is with us today to talk about Transcranial Magnetic Stimulation (TMS). TMS is a relatively new treatment, at least in the United States, for individuals who are struggling with depression. Depression is often present in addiction and TMS is something that may help people that are struggling with addiction and treatment-resistant depression. Suzanne Jesse is the CEO and founder of Anew Era TMS in Huntington Beach, California. To start, Suzanne breaks down what TMS stands for. Transcranial means “beneath the cranium,” and magnetic stimulation means “stimulation using magnets.” The technology behind MRI magnets is used in TMS. But the big difference between TMS and MRI magnets is that the TMS magnetic technology creates a field of energy that is fairly intense that penetrates beneath the cranium into the brain. TMS focuses in on the mood center of the brain that is responsible for the depressive symptoms. That area is stimulated to wake up those neurons again so that they are able to fire efficiently and transmit the neurotransmitters across the synaptic gap more efficiently. For patients that have tried psychotherapy, and medications, and they haven't seen the results that they are looking for, TMS may be very beneficial. Even though TMS has been used in Europe and Asia for more than 20 years, it is now being used in the United States. This use is mainly due to TMS being approved by the FDA for depression, but it can also be used to treat conditions like PTSD, OCD, anxiety, smoking cessation. It has also been used to address issues like dementia and Alzheimers. This cutting-edge technology has so many different opportunities for treatment that weren't available before TMS coming to the United States. TMS is completely noninvasive. Patients can drive themselves in, have a 45-minute treatment, and then drive themselves home. The only possible side effects are sometimes a mild headache. Suzanne encourages people to come in for a free consultation and see the equipment. Her team of psychiatrists will do an overall assessment to see if this type of treatment is appropriate for you. Supporting Resources: visit https://aneweratms.com/ Or call (888) 503-1549 NovusMindfulLife.com Episode Credits If you like this podcast and are thinking of creating your own, consider talking to my producer, Emerald City Productions. They helped me grow and produce the podcast you are listening to right now. Find out more at https://emeraldcitypro.com Let them know we sent you. Follow and Review: We'd love it even more if you could drop a review or 5-star rating over on Apple Podcasts. Simply select “Ratings and Reviews” and “Write a Review” then a quick line with your favorite part of the episode. It only takes a second and it helps spread the word about the podcast. Supporting Resources: If you live in California and are looking for counseling or therapy please check out Novus Mindful Life Counseling and Recovery Center NovusMindfulLife.com We want to hear from you. Leave us a message or ask us a question: https://www.speakpipe.com/addictedmind Disclaimer Learn more about your ad choices. Visit megaphone.fm/adchoices
Join Cody Bryant, a brain injury survivor, as he shares his recovery journey, including his accident in Spain, challenges with care, and neuro rehab experience. Cody discusses the changes in his personality, relationships, and emotional regulation post-injury. He emphasizes self-care strategies like meditation and explores topics such as diet, supplements, TMS, physical therapy, and navigating the healthcare system. Cody and Eryn also highlight the importance of community support and vulnerability in the healing process.Keywordsbrain injury, recovery, challenges, care, personality changes, relationships, emotional dysregulation, self-care, meditation, brain injury, rehabilitation, diet, nutrition, supplements, grounding, transcranial magnetic stimulation, TMS, physical therapy, healthcare system, community, vulnerabilityTakeaways· Brain injury survivors often face challenges in receiving proper care, especially when abroad.· Personality changes and emotional dysregulation are common after a brain injury, and it can be difficult for loved ones to adjust to these changes.· Self-care is crucial for brain injury survivors, and finding strategies like meditation can help manage the effects of the injury.· Social engagement can be draining for brain injury survivors, and it's important to find a balance between pushing oneself and avoiding brain fatigue.· Diet and nutrition play a significant role in brain injury recovery, but healthcare professionals often overlook this aspect.· Supplements and grounding techniques can also support brain injury recovery.· Transcranial magnetic stimulation (TMS) may improve social stamina and have positive effects on depression and PTSD.· Neuro IFRAH is a systematic approach to physical therapy that can help regain motor function after a brain injury.· The healthcare system often fails to recognize the long-term nature of brain injury recovery and the need for ongoing support.· Sharing experiences and being part of a supportive community can provide motivation and a sense of purpose in the recovery journey.Sound Bites"I thought everyone was trying to kill me and I thought they were trying to steal my genetics.""I was ripping out my IV and catheter constantly.""People closest to me basically had to grieve the person I used to be.""I started reading that book and that was kind of my initial start of recognizing that nutrition played a big role in recovery.""I do like a urine test every morning to make sure I'm in ketosis.""I wear this helmet that puts these electromagnetic waves through my brain for anywhere from 30 minutes to an hour every day."Chapters00:00 Introduction and Apology for Guest Absence01:07 Guest Introduction: Cody Bryant01:39 Cody's Accident in Spain and Severe Traumatic Brain Injury03:42 Challenges in Receiving Proper Care05:18 Fear and Delirium in the ICU08:35 Transfer to Neuro Rehab and Limited Stay10:08 Difficulties in Recognizing Brain Injury11:49 Struggling with Identity and Personality Changes14:29 Impact on Relationships and Grieving the Old Self17:39 Emotional Dysregulation and Mood Swings19:23 Navigating Relationships and Understanding Triggers21:23 Using Meditation as a Reset and Self-Care Strategy23:25 Balancing Pushing Oneself and Avoiding Brain Fatigue26:52 The Role of Diet and Nutrition29:29 Supplements and Grounding...
I'm honored to have Dr. Richard Bermudez, the National Medical Director at Brainsway, joining us. Dr. Bermudez is a pioneer in transcranial magnetic stimulation (TMS), a groundbreaking treatment for mental health conditions like depression and anxiety. With years of expertise in neuroscience and psychiatry, he has made it his mission to expand the accessibility and efficacy of innovative mental health therapies. Today, he'll share his journey from electrical engineering to medicine and how it shaped his passion for non-invasive brain stimulation treatments. We dive into the science behind TMS and how it differs from traditional mental health treatments like medication and talk therapy. Dr. Bermudez explains the evolution of TMS technology, including its ability to stimulate specific brain networks through advanced coil designs. We'll also discuss the transformative outcomes TMS provides for patients, as well as its potential for treating conditions beyond depression, from obsessive-compulsive disorder to nicotine dependence. Whether you're a clinician, a mental health advocate, or simply curious about this cutting-edge therapy, this discussion promises to be both educational and inspiring. As we explore TMS, Dr. Bermudez highlights its safety, versatility, and unique role in fostering neuroplasticity. He compares TMS with other emerging treatments like ketamine therapy and discusses the collaborative innovations underway at Brainsway. This episode is a must-listen for anyone interested in mental health, neuroscience, or the future of non-invasive treatments. [03:32] We've had great success with TMS at Camelback Integrated Health and Wellness. [04:14] Dr. Bermudes started out as an engineer and ended up switching to biology in college. [05:38] He worked in a physiology lab doing neurophysiology research and brain stimulation. He learned that the brain was an electrochemical organ. [06:22] He ended up going into medicine and psychiatry. He became clinically interested in non-invasive brain stimulation. [08:44] Brainsway is like a family with a very collaborative culture. They want to transition into a true neuroscience technology company. [10:03] It's an exciting time for the organization and for neuroscience. [13:23] How TMS differs from traditional medications or therapies. Transcranial means it's across the skull but it's not invasive. They use a high-powered magnet to induce a small electrical current. [15:40] Brainsway developed their technology in conjunction with the NIH and their coils are what are called complex coils. [16:47] 8 out of 10 patients have had a clinically significant change in their depression score. [19:07] There are three brain networks responsible for our mental health and Brainsway has three different helmets and coils. Each one modulates a different network. [21:47] TMS is safe and good for all of our brains. It induces neuroplasticity. [23:22] Deep TMS and standard TMS. Deep TMS stimulates more areas of the networks. [26:54] Functional MRIs and studies related to TMS. [28:33] Neurological changes that TMS produces in the brain. TMS belongs with the other pillars of substance abuse treatments. [30:01] We learn about conditions that TMS is cleared to treat. [39:58] There are different targets or areas of the brain that need to be modulated to affect different brain networks. There's not a lot of evidence that TMS would work for bipolar mania or autism or ADHD. [43:22] We learn about the typical TMS protocol and how long it takes to start to see results. [51:20] Dr. Bermudes talks about accelerated protocols and the use of TMS and ketamine. [55:00] Avoiding toxic conversations and watching the news. You don't want negative experiences on your plastic brain. The patient experience is important and it's good to have a calm, safe, welcoming environment. [57:17] TMS and psychedelics like ketamine. They both have glutamate which is our excitatory neurotransmitter. [59:06] Things to think about when deciding between TMS or ketamine. [01:03:22] Safety profiles of TMS versus ketamine. Safety concerns for TMS include not having any metal in your head and likelihood of having seizures. [01:12:00] Misconceptions about TMS. [01:14:11] Accessibility and insurance cost for TMS. [01:20:34] A device based treatment that doesn't require a doctor or a psychiatrist will help address the shortage of psychiatric prescribers. [01:21:53] It's surprising how many research articles about TMS are available now. Links mentioned in this episode: Camelback Recovery I Love Being Sober YouTube BrainsWay Knowledge Center Dr. Richard Bermudes Brainsway Dr. Richard Bermudes LinkedIn
An exciting new study has found that red light therapy can help in reversing Hashimoto's! 30-50% of patients could stop their thyroid medication. In this episode, I'll explain how the thyroid is affected by red light therapy, and the best protocol to follow for healing. Learn more! Recommended devices: PlatinumLED Therapy Lights: BIOMAX Series https://platinumtherapylights.com/products/biomax-rlt Mini Red Light Therapy Device: https://us.boncharge.com/products/mini-red-light_device Timestamps: 00:00 Intro 01:16 How red light therapy works 06:25 Proven benefits for Hashimoto's 11:58 Other benefits 13:46 Device recommendations 16:16 Red light therapy protocol 20:56 Efficacy of LEDs vs. lasers
Greg and Matias interview Jay Sanguinetti, founder of Sanmai Technologies, a startup using transcranial focused ultrasound for the treatment of mental health conditions. Jay has a background in academia, having worked at the University of Arizona and started the SEMA Lab (Science Enhanced Mindful Awareness).In this episode, we discuss:The science behind transcranial focused ultrasound and its therapeutic potential for mental healthThe risks and considerations involved in using focused ultrasound technology for mental health treatmentsJay's experience transitioning from academia to founding a mental health technology startupThe regulatory landscape that Sanmai Technologies will navigate as they bring this novel neurotechnology to marketCredits:Created by Greg Kubin and Matias SerebrinskyHost: Matias Serebrinsky & Greg KubinProduced by Jonathan A. Davis, Nico V. Rey & Caitlin NerFind us at businesstrip.fm and psymed.venturesFollow us on Instagram and Twitter!Theme music by Dorian LoveAdditional Music: Distant Daze by Zack Frank
Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: All The Latest Human tFUS Studies, published by sarahconstantin on August 10, 2024 on LessWrong. Transcranial focused ultrasound neuromodulation - altering the brain's activity with low-intensity ultrasound - is really exciting . It allows us to manipulate arbitrary regions of the brain without surgery, potentially replacing the (brain-damaging) electrode implants currently used for serious neurological conditions like epilepsy and Parkinson's, and potentially also expanding applications of brain stimulation to milder conditions not worth the risks of brain surgery, like mental illness, addiction, or chronic pain. The field is rapidly growing, and since I wrote my earlier post series there have been quite a few human studies published. Here's a systematic overview of all the human studies published in 2024, by target brain region. Headline Results This year's papers further confirm, to start with, that ultrasound does things to brain activity, if that was still in doubt, and that it is safe enough to run human experiments with (no adverse effects during experiments with small numbers of participants and brief exposures.) There are notably inconsistent results in whether targeting ultrasound to a given brain area increases or decreases neural activity in that area, even in some cases when the same area is targeted with the same sonication parameters! We clearly need to get a better sense of what ultrasound even does. Most studies don't do the obvious (but admittedly expensive) thing of confirming a change in neural activity via a noninvasive measure like fMRI. Those that do, show different results (more activity in the targeted region, less activity in the targeted region, or neither) depending on which region is targeted; this tells us that "tFUS" as a class doesn't have a globally consistent effect on targeted neural activity. Again, still more to learn. However, despite the primitive state of our understanding of this modality, we do already seem to have some strikingly useful results. Ultrasound stimulation of the thalamus seems to be helpful for essential tremor, stimulation of the posterior insula seems to reduce pain sensitivity, and stimulation of the anterior medial prefrontal cortex seems to have quite strong effects on depression. These are before vs. after results without a control group, not randomized controlled studies, but I think they at least warrant followup. I'm not as excited as I'd want to be about Jay Sanguinetti's default-mode-network-inhibition study. The effects seem subtle and game-able; and anecdotally the stories I hear from people who've tried the protocol from his lab are not "I was in a clearly altered state". But all in all, it continues to be a promising field; tFUS clearly does things, some of those things may be useful, and the more data we get, the closer we'll get to an actual model of what it does. Amygdala Chou, et al1 at Harvard Medical School tested tFUS2 on the left amygdalas of 30 healthy volunteers. Compared to sham stimulation, tFUS resulted in less fMRI-measured activity in the amygdala. The amygdala is involved in fear responses, so reducing amygdala activity could have uses in anxiety disorders and phobias. Hoang-Dang, et al3 at UCLA used tFUS4 on the right amygdala of 21 older adults, and found no effect on state anxiety after tFUS, but did show an increase in negative emotional reaction to viewing negative images. There was also a significant increase in heart rate between trials of this mildly stressful task. Since the amygdala is usually active during fear, this suggests that these stimulation parameters may have activated the amygdala…despite the other study using similar parameters and showing a direct decrease in amygdala activity. The UCLA study doesn't mention the duration of tFUS stimulation, which may be a re...
Link to original articleWelcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: All The Latest Human tFUS Studies, published by sarahconstantin on August 10, 2024 on LessWrong. Transcranial focused ultrasound neuromodulation - altering the brain's activity with low-intensity ultrasound - is really exciting . It allows us to manipulate arbitrary regions of the brain without surgery, potentially replacing the (brain-damaging) electrode implants currently used for serious neurological conditions like epilepsy and Parkinson's, and potentially also expanding applications of brain stimulation to milder conditions not worth the risks of brain surgery, like mental illness, addiction, or chronic pain. The field is rapidly growing, and since I wrote my earlier post series there have been quite a few human studies published. Here's a systematic overview of all the human studies published in 2024, by target brain region. Headline Results This year's papers further confirm, to start with, that ultrasound does things to brain activity, if that was still in doubt, and that it is safe enough to run human experiments with (no adverse effects during experiments with small numbers of participants and brief exposures.) There are notably inconsistent results in whether targeting ultrasound to a given brain area increases or decreases neural activity in that area, even in some cases when the same area is targeted with the same sonication parameters! We clearly need to get a better sense of what ultrasound even does. Most studies don't do the obvious (but admittedly expensive) thing of confirming a change in neural activity via a noninvasive measure like fMRI. Those that do, show different results (more activity in the targeted region, less activity in the targeted region, or neither) depending on which region is targeted; this tells us that "tFUS" as a class doesn't have a globally consistent effect on targeted neural activity. Again, still more to learn. However, despite the primitive state of our understanding of this modality, we do already seem to have some strikingly useful results. Ultrasound stimulation of the thalamus seems to be helpful for essential tremor, stimulation of the posterior insula seems to reduce pain sensitivity, and stimulation of the anterior medial prefrontal cortex seems to have quite strong effects on depression. These are before vs. after results without a control group, not randomized controlled studies, but I think they at least warrant followup. I'm not as excited as I'd want to be about Jay Sanguinetti's default-mode-network-inhibition study. The effects seem subtle and game-able; and anecdotally the stories I hear from people who've tried the protocol from his lab are not "I was in a clearly altered state". But all in all, it continues to be a promising field; tFUS clearly does things, some of those things may be useful, and the more data we get, the closer we'll get to an actual model of what it does. Amygdala Chou, et al1 at Harvard Medical School tested tFUS2 on the left amygdalas of 30 healthy volunteers. Compared to sham stimulation, tFUS resulted in less fMRI-measured activity in the amygdala. The amygdala is involved in fear responses, so reducing amygdala activity could have uses in anxiety disorders and phobias. Hoang-Dang, et al3 at UCLA used tFUS4 on the right amygdala of 21 older adults, and found no effect on state anxiety after tFUS, but did show an increase in negative emotional reaction to viewing negative images. There was also a significant increase in heart rate between trials of this mildly stressful task. Since the amygdala is usually active during fear, this suggests that these stimulation parameters may have activated the amygdala…despite the other study using similar parameters and showing a direct decrease in amygdala activity. The UCLA study doesn't mention the duration of tFUS stimulation, which may be a re...
In this episode Dr. Lyon sits down with Dr. Erik Won, President and Chief Medical Officer of WAVE Neuroscience Biotechnology. Dr. Won shares his journey from being a Navy flight surgeon to leading groundbreaking research in brain health. If you struggle with brain fog, depression, PTSD, or traumatic brain injury, this episode is for you. Learn about innovative treatments that are changing lives and providing hope for those suffering from brain-related conditions. Don't miss this enlightening conversation on the future of neuroscience!Dr. Erik Won is President and Chief Medical Officer of Wave Neuroscience, Inc; a biotechnology company that has innovated breakthrough technologies called Magnetic e-Resonance Therapy (MeRT) and Synchronized Transcranial Magnetic Stimulation (sTMS). These technologies utilize computational neuroanalytics and brain imaging to customize treatment protocols with the aim of restoring optimal neurological function. These modalities represent a form of precision-guided medicine that has been researched or is currently being used by premier institutions such as US Special Operations Command, Stanford University School of Medicine, Duke University - Human Performance Opti-Lab, University of Southern California (USC) Center for Neurorestoration, the University of California Los Angeles (UCLA) - David Geffen School of Medicine, University of Pennsylvania, Brown University, and the Texas A&M Institute for Bioscience and Technology, among others. Erik joined Wave Neuroscience after serving as the Chief Physician and Chief Technology Officer (Health Services) for the Boeing Company. He also served as a US Navy Flight Surgeon for Marine Medium Helicopter Squadron 268, and received the distinction of serving as the ACE Flight Surgeon for the 11th Marine Expeditionary Unit, 1st Marine Expeditionary Force. Dr. Won has been published in numerous peer-reviewed journals, textbooks, and presented in numerous academic conferences. He completed his residency at the Harvard OEM combined residency program and was appointed Chief Resident. He received a Masters in Public Health (MPH) from the Harvard School of Public Health and Masters in Business Administrations (MBA) from the University of Southern California, Marshall School of Business.
Download the 12-Page "Omega-3 Supplementation Guide" Discover my premium podcast, The Aliquot Join over 300,000 people and sign up for my newsletter Become a FoundMyFitness premium member to get access to exclusive episodes, emails, live Q+A's with Rhonda and more Dr. Andrew Huberman is a Stanford professor, neurobiologist, and host of the incredibly popular Huberman Lab Podcast. He's also the guest on this episode of the FoundMyFitness podcast. Our conversation encompasses an in-depth discussion of the brain's dopamine system and provides a toolkit for enhancing motivation and focus. In this episode, we discuss: (00:07:58) Dopamine is a neuromodulator, not a neurotransmitter (00:09:50) Dopamine's role in motivation & pursuit (00:14:56) The dopamine wave pool analogy (00:20:19) Strategies to minimize the dopamine-triggering effects of smartphone use (00:23:53) Why dopamine peaks without effort are dangerous (00:27:13) The number one sign of a highly motivated individual (00:29:20) Dopamine reward prediction error (00:31:39) How effort and anticipation influence dopamine release (00:33:42) Does lacking motivation reflect dopamine system deficits? (00:38:21) Why focus & motivation circuits are like exercise (00:42:37) Why attaching reward to effort itself is the holy grail of learning (00:44:03) Unpacking the concept of “limbic friction” (00:47:53) How setbacks provide crucial feedback to your dopamine system (00:52:09) Why the real reward lies in the process (00:53:12) Why parents should reward verb states instead of providing adjectives (00:55:26) Boosting motivation with visualization of negative outcomes (00:58:12) How to overcome procrastination (01:04:12) How does exercise affect the dopamine system? (01:08:56) Deliberate cold exposure vs. drug highs (01:10:50) The entrainment effect of same-time exercise (01:14:45) Why you shouldn't rely on stimulants when lacking motivation (01:15:29) How caffeine affects motivation (01:16:02) Why Dr. Huberman limits his nicotine consumption and may quit (01:19:26) The pitfalls of artificial stimulants (01:22:13) Why Andrew "counts walls" during deliberate cold exposure (01:27:05) Cold exposure parameters for increasing dopamine (01:29:39) Cold plunge alternatives for replenishing the dopamine pool (01:30:56) Why Andrew limits most workouts to 80-85% intensity (01:33:58) Using exercise & cold exposure as stimuli for the brain (01:36:29) The anterior midcingulate cortex (aMCC) (01:38:52) Transcranial magnetic stimulation (01:41:43) What does Dr. Huberman think of Neuralink? (01:44:49) How non-sleep deep rest (NSDR) replenishes dopamine levels (01:51:24) Why NSDR may teach people to become better at sleeping (01:55:06) Rhonda's experience trying NSDR after a night of poor sleep (01:56:25) Possible creativity & trauma therapy benefits of NSDR (01:59:36) How to cultivate a healthy relationship with social media (02:01:09) Dr. Huberman's insights on social media detachment and usage limits (02:06:05) Dr. Huberman on the unique psychosocial dynamics of X (formerly Twitter) (02:07:26) Andrew's recommended daily use limit for Instagram (02:10:00) Is social media increasing the prevalence of ADHD? (02:11:41) Why Andrew recommends setting social media constraints (02:13:44) Social media makes grown adults behave like teenagers (02:14:53) Is social media increasing divorce rates? (02:17:33) How low solar angle sunlight affects the circadian rhythm (02:27:31) How to limit the adverse effects of late-night artificial light (02:29:18) The light bulb that mimics sunrise and sunset (02:30:30) How to spike morning cortisol by 50% (02:31:42) What's the optimal time to view morning sunlight? (02:32:32) Can light panels replace viewing morning sunlight? (02:33:54) Combatting laptop & phone use with long distance viewing (02:40:27) Why Andrew recommends limiting alcohol to 0-2 drinks per week (02:48:30) How does alcohol affect the dopamine and serotonin systems? (02:54:08) Treating ADHD with prescription drugs, supplements, & behaviors (02:58:51) Factors contributing to the possible overdiagnosis of ADHD (03:02:17) Do people with ADHD lack focus capacity? (03:03:30) Can behavioral modifications replace the need for ADHD drugs? (03:05:21) Andrew's weekly workout routine (03:11:04) Andrew's diet & why his dinners are higher in carbs (03:12:00) Modulating stress with the physiological sigh (03:12:55) Andrew's supplement routine (03:15:21) Andrew's experimentation with peptides (03:17:35) How Andrew gauges supplement, diet, & workout routine effectiveness (03:20:31) How does Andrew deal with negative comments & press? Watch this episode on YouTube Show notes are available by clicking here
This week we are going to cover a wide array of research: Mitophagy's impact on aging (the mitochondria's process of selective degradation of mitochondria by autophagy). If you can't get rid of the garbage mitochondria, that's a rotten deal for your health. Methylene blue's role in combatting oral biofilm (a sticky film that coats teeth and contains bacteria). Our blue friend may actually be playing a beneficial role by temporarily staining your teeth blue. Who wouldn't trade tooth decay, receding gums and bad breath for that? Preconditioning your muscles for improved muscular strength, endurance and recovery. In reality, how beneficial is this strategy for the active population? Transcranial photobiomodulation for children with autism spectrum disorder. Is this an efficacious treatment for children to mitigate symptoms of ASD? If you found the information in today's episode particularly interesting and/or compelling, please share it with a family member, friend, colleague and/or anyone that you think could benefit and be illuminated by this knowledge. Sharing is caring :)As always, light up your health! - Key points: Introduction and New Product Announcement (00:00:00 - 00:01:03) BioCream Stock Update (00:01:03 - 00:01:56): Supply exhausted in four days; restock in one to two weeks; updates on BioLight channels. Mitochondria and Aging Research (00:01:56 - 00:06:00): Mitochondrial dysfunction, oxidative damage, inflammation. Autophagy and mitophagy's role in aging. Benefits of Healthy Mitochondria (00:06:00 - 00:11:57): Healthy mitochondria reduce inflammation and slow aging. BioBlue offer: 15% off with code BIOBLUE15. Microbial Biofilms and Infection (00:11:57 - 00:17:00): Photodynamic therapy (PDT) with methylene blue and red LEDs effective in reducing biofilm activity. Methylene Blue's Biocidal Activity (00:17:00 - 00:21:37): Methylene blue's broad biocidal activity; further studies needed for clinical efficacy in biofilm treatment. Preconditioning with Red Light Therapy (00:21:37 - 00:27:07): Enhances muscle performance, brain function, and skin resistance to UV. Meta-Analysis on Red Light Therapy (00:27:07 - 00:32:00) Benefits for Active Individuals (00:32:00 - 00:34:41): Red muscle fibers benefit more from red light therapy. Study on tPBM in Children with ASD (00:36:41 - 00:37:39): Shows safety, efficacy, and symptom improvement. ASD Pathology and tPBM Benefits (00:37:39 - 00:41:37): Brain abnormalities, neuroinflammation, and mitochondrial dysfunction. tPBM Effectiveness and Safety (00:41:37 - 00:45:09): Improves ASD symptoms with specific near-infrared light parameters; safe and effective. tPBM for Early ASD Intervention (00:45:09 - 00:46:52): Potential in treating ASD; early intervention is crucial; further research needed. Encouragement and Future Content (00:46:52 - 00:50:18): Encouragement to review podcast; upcoming expert interviews and red light therapy research. Appreciation and Staying Informed (00:50:18 - 00:51:27): Appreciation for listener support; stay informed on red light therapy benefits. - Articles referenced: Inflammation and mitophagy are mitochondrial checkpoints to aging Antimicrobial Activity of Methylene Blue Associated with Photodynamic Therapy: In Vitro Study in Multi-Species Oral Biofilm Can pre-exercise photobiomodulation improve muscle endurance and promote recovery from muscle strength and injuries in people with different activity levels? A meta-analysis of randomized controlled trials Transcranial photobiomodulation in children aged 2–6 years: a randomized sham-controlled clinical trial assessing safety, efficacy, and impact on autism spectrum disorder symptoms and brain electrophysiology - Introducing the newest BioBlue product: BioBlue (SR) — a 50/50 blend of methylene blue and leucomethylene blue! For the next week, save 15% on BioBlue (SR) single bottle orders using coupon code "SR15" - Introducing the Red Light Therapy Treatment Protocols Ecosystem! - To learn more about red light therapy and shop for the highest-quality red light therapy products, visit https://www.biolight.shop - Dr. Mike's #1 recommendations: Grounding products: Earthing.com EMF-mitigating products: Somavedic Blue light-blocking glasses: Ra Optics - Stay up-to-date on social media: Dr. Mike Belkowski: Instagram LinkedIn BioLight: Website Instagram YouTube Facebook
In this episode, Dr. Rountree discusses a newly released study detailing photobiomodulation and various brain disorders.Read the full study discussed in this episode --Transcranial photobiomodulation for brain diseases: review of animal and human studies including mechanisms and emerging trendsYouTube ChannelView the many other episodes and videos available here Laser Therapy InstituteFurther Resources:Success with Laser Therapy Flowchart & Checklist InfographicCheck out these FREE Provider ResourcesRead about laser research on the LTI BlogLearn more about what we offer on the LTI websiteFind out how you can Customize your LTI experience
In this enlightening episode of Wellness at the Speed of Light, join Dr. Keerthy Sunder, a trailblazer in the field of psychiatry, as he shares his transformative journey from obstetrics and gynecology to becoming a leading figure in mental wellness. Discover the innovative treatments that are at the core of his practice, including Transcranial Magnetic Stimulation (TMS) and NuCalm, and learn how these technologies are changing the face of mental health care. Dr. Sunder's holistic perspective emphasizes the vital connection between mental and physical health, offering paths to wellness that go beyond conventional methods. This episode is a must-listen for anyone interested in the future of mental health, the science of well-being, and the power of innovative, compassionate care. Keywords: Mental Health, Dr. Keerthy Sunder, Psychiatry, Innovation, TMS, NuCalm, Holistic Care, Wellness, Depression, PTSD, Stress Management
Peter Adams, Senior executive manager with consistent track record of high achievement in Europe, USA and Canada. Depth of experience in the building of technology based organizations, quickly developing and implementing strategies and creating market awareness. Experience developed through blue chip, startup, and consulting organizations plus management of independent business. Consistently exceeds targets within budget limits. Experience spans healthcare, semiconductors, software,IT services,systems and systems integrationSHOWNOTES:
Transcranial magnetic stimulation (TMS) represents an exciting non-medication and noninvasive option for treatment of some brain health conditions, specifically TMS for depression. TMS works by using magnetic therapy in the form of magnetic field pulses to stimulate the brain's nerve cells to alleviate the symptoms associated with depression. In addition, there is growing research exploring the effectiveness of TMS in other neurological conditions, including Alzheimer's disease and other memory disorders.At Pacific Brain Health Center, Dr. David Merrill offers TMS for depression using a MagVenture device. It offers a unique, short, 3 minute TBS (theta burst) protocol for the treatment of Major Depressive Disorder in adult patients who have failed to receive satisfactory improvements from prior antidepressant medication in the current episode.
Join hosts Jaysson T. Brooks, MD and Terrance G. Ishmael, MBBS as they interview M. Wade Shrader, MD regarding their article - "Transcranial electric motor evoked potential monitoring during scoliosis surgery in children with cerebral palsy and active seizure disorder: is it feasible and safe?" - in the July 2023 issue of Spine Deformity, the official journal of SRS.
We take our first look at a Flash-affiliated character with Barry Allen's nemesis EOBARD THAWNE! Things go off the rails pretty quickly, but it's ok, because we can just jump to another timeline where everything is fine, and no one will be any the wiser - except for Eobard... Intro Background (2:05) Eobard Thawne, aka Professor Zoom or the Reverse Flash, created by John Broome and Carmine Infantino in The Flash #139 (Sept. 1963) Eobard Thawne is a scientist from the 25th century, where superheroes are few He becomes obsessed with learning about the Speed Force, but he initially encounters some obstacles until his future self intervenes several times: He was jealous of his younger brother growing up, until his future self prevented Robern from being born and then his future self caused the death of his parents, since they were worried about his obsession He kills another professor who is close to unlocking the secrets of the Speed Force After Eobard falls in love with a reporter, his future self kills her fiance and any man she ever dated - when she still rejected him, his future self went back to her childhood and traumatized her to the point of rendering her mute He becomes obsessed with Barry Allen, to the point of getting cosmetic surgery to resemble him Obtains a Cosmic Treadmill, a copy of the Flash's costume, and replicates the accident to give himself Flash's powers - he traveled back to a few years after Barry's death, and learned that he would become Professor Zoom, the Reverse-Flash, and Barry's greatest nemesis This caused a psychic break, and Thawne became convinced he *was* a resurrected Barry Allen, and even managed to convince several of Barry's friends he was Barry - after attacking several heroes for “forgetting” him, Wally West tricked him into returning to his home time Thawne became obsessed with replacing Barry, to the point of killing Iris West, and when he attacked Fiona Webb, Barry broke his neck and killed him Flash: Rebirth reveals that Thawne is responsible for every tragedy in Barry's life, including the death of his mother - after killing several speedsters, he announces his connection to the Negative Speed Force, and says he will kill Iris before Barry has a chance to meet her - as Barry and Wally travel backwards in time, they merge into the lightning bolt that originally gave Barry his powers #BecauseComics - Thawne is imprisoned in a device that severs his connection to the Speed Force, removing his powers The broken neck version was resurrected during Blackest Night and then purified by a white light Thawne is the central villain of Flashpoint - when Barry travels back to prevent Thawne from killing Nora West, the resulting timeline is drastically different - Thawne is then killed by the new Batman, and Barry goes back to prevent himself from stopping her murder, which creates a new third timeline Rebirth revises his origin - he's met in the 25th century by Barry, who prevents him from carrying out further crimes - he is temporarily rehabilitated, until he travels to the past and learns Barry didn't consider him as much of a friend as he initially thought, so he vows to make Barry miserable until Barry “makes time” for him He's one of the primary villains of the Button, where he has memories of every timeline, and uses this knowledge to torture Barry, Bruce Wayne, and heroes, until he's killed by Dr. Manhattan, although he's resurrected by the negative Speed Force once again Finish Line - Thawne vibrates into Barry, taking over his mind and trapping Barry in the Speed Force - Thawne says he and Barry will forever be trapped in a loop, until Barry forgives him - this confuses Thawne, and Barry is able to reset him in the 25th century, where he is a tour guide at the Flash Museum with no memory of being a villain Issues - “Eobard Thawne. The man who reads the Evil Overlord List and reacts with an oblivious bemusement. The man with an absolute pathological need to prove himself superior to everyone around him to the point where even other villains hate his guts. Thawne has spent the last 60 years elevating the concept of the Villain Ball to an almost comical extent, and is fortunately so ridiculously chatty and forthcoming about himself and his feelings that we can easily mine a ton of his many issues from it to figure out why.” (15:56) Absolute obsession with and desire to replace The Flash. Thawne comes from a time when superheroes are thought of as a quaint anachronism, and striving to be one would be like someone today saying their dream was to be a medieval knight. But he idolized the era and The Flash in particular enough to become obsessed with becoming him. After recreating the accident that gave The Flash his super speed and traveling back in time to meet his hero, he found out that his destiny was instead to become The Flash's greatest enemy, and it simply broke him inside. From then on, his entire reason for being became wrapped around inserting himself into Barry's life, alternating between trying to ruin it and trying to usurp it. He tried getting Barry's wife to fall in love with him, tried to take Barry's place in the original accident and become the original Flash, and ultimately settled on using his time travel ability to become the source of every bad thing that ever happened in Barry's life. It's not an exaggeration to say that Thawne does not have or want a life of his own; he actually does want Barry's for himself. Superiority complex. When you think about Eobard Thawne is actually capable of doing, it's a real wonder why he ever fails at anything at all. The man can move at many times the speed of light. He can cross the room and shred your heart before your eyes can even send the signal to your brain that it's happening. He can kill a room full of a hundred people in a hundred different ways before any of them could react. All of which pales in comparison to his mastery of time travel. If anyone or anything is an obstacle to his objectives or even so much as affronts his sight, he can go back in time and completely erase it from existence. That's an actual thing he does with regularity. There is quite literally no goal on any scale he could not achieve with his powers. But that's simply not enough for him. At the moment of every single one of his triumphs, he has to let everyone in earshot know that it was him who did it. He grandstands and gloats about his success, explaining in great detail everything he did, how he did it, and how powerless everyone is to stop him from keeping on doing whatever he wants. Invariably, this winds up with the heroes either having the time to make their move or having the exact information they need to stop him. Thawne didn't invent Evil Monologuing by any stretch, but he's perfected it to an art form. It's a pathology with this man. He has to have you acknowledge his greatness, or he doesn't consider it a victory. There is no limit to what he could achieve if he just didn't care about getting the credit for it. (22:18) Pettiness on a scale hitherto undreamt of. To paraphrase Billy Beane in Moneyball, there's petty, there's that which petty aspires to be, there's fifty additional magnitudes of petty that the English language doesn't have words for, and then there's Thawne. The man responds to personal slights as if they were absolute declarations of war. He has completely erased his younger brother from existence because he thought his parents loved him more. He got a crush on a woman and erased her husband and all of her ex-boyfriends from existence so she'd have no reason not to date him, then when she still rejected him, he traveled back in time and repeatedly traumatized her as a child to the point where she wound up in a permanent vegetative state for the rest of her life. He found a limiting factor on his time travel that he couldn't kill Barry Allen or do anything that prevents him from becoming The Flash, so instead he settled on simply becoming the direct cause of every bad thing that's ever happened in his life, including things so minor as making him late for class in school and making him miss a catch in a baseball game. He's done this with villains who annoy him as well; Hunter Zolomon owes the entire line of tragedies that led to him becoming Professor Zoom to Thawne traveling through time and causing them. There is no slight so trivial that Thawne won't respond to it with the most disproportionate retribution he can imagine. (28:28) Dozens and dozens of lifetimes worth of memories. Thawne's use of the Negative Speed Force gives him a form of superceding time travel. He can alter history and retain the memories of his life and the world exactly as it was before he changed it. Unfortunately, he has time traveled and altered history so many times and so drastically that his memories now consist of dozens of lifetimes all folded into themselves. He remembers every version of himself in every timeline he's ever existed in, and every version of every other important person in his life and how their histories have changed as well. It all just blends together for him in a way that makes absolutely no linear sense trying to keep it all straight. That has to be absolutely maddening; like a Mandela Effect, but for your entire life, and multiplied by every single time he changes the timeline. No one else remembers anything in the same way that he does, and there's absolutely no way he can convince anyone about the way things used to be. (38:22) Break (45:33) Plugs for Ignorance Was Bliss, Geek Peak, and Gail Simone Treatment (46:46) In-universe - Transcranial magnetic stimulation analogue to help Thawne's brain Out of universe - Use CBT to help people to slow down and notice things more (49:40) Skit (54:34) Hello Mr. Thawne, I'm Dr. Issues. Hmm…you seem out of breath - *heavy breathing* It took a lot for me to get here. But I can't ignore a slight like that. As you know, a doctor should only address a colleague with a title the equivalent to their own. You can't be serio…ow! What was that? -The skin of the areola is incredibly sensitive to certain angular forces. Your nerve endings are actually a bit different based on your scream. Most people have a heightened reaction from the pain itself, but for you, the mere sensation of unexpected touch and pressure were too much for you. *yawn* But as all plebians before you, your nervous system stood no chance in keeping up with my abilities. And that, my dear doctor, was only a sample of what I am capable of. *pause* You just gave a soliloquy on a purple nurple? -I had to demonstrate that you are not superior to me in any aspect of existence. Ok -*pause* That's it? Just, “OK?” You don't protest? Where's the fear? Where's the awe? Anger? Something besides “Ok”? Okaaaaay…Professor? -That's better…wait, still no emotion behind it. What is wrong with you? Do I have to phase through you and shatter your spleen? Needlessly graphic but no…*sigh* Look, I'm not superpowered, you're not controllable, so I'm a sitting duck just for agreeing to meet with you, no matter what safeguards I may have thought of. -That was very naive of you. I'd be insulted if I didn't already feel insulted about the fact that some version of me that I talked with at some point in the future thought this was a good idea. What will I be thinking? Um…was thinking. You get the point. Sure. So, what can I do for you? -There's someone I know that I used to idolize. Now I hate him. He killed me, but I came back. Now I can't destroy him because I want to exist, but I want to ruin every part of his life. You know, “as you do” Are you expecting me to empathize with that? OOOOF; what did you do now? -Matter has multiple phases. Most people will only experience the most basic solid, liquid, and gas. But, as a scientist at heart, I'm sure you're aware of plasma. Under typical Earth conditions, you would only be able to withstand a nanoparticle of any element in a picosecond of time as it sublimates from a liquid format and dissipates instantaneously in some form of biological substrate in an elongated but small cavernous bony structure with a malleable yet firm membrane *Interrupting* You spit in my ear?! What are you, 12?! - Superspeed saliva, sir! It's your privilege. The fact that your head did not disintegrate is only because I can control my mouth and tongue with exquisite precision. You could kill me at any moment, and you torture me with pranks? What's the point? -I've given you a glimpse of my power. Now imagine that for every moment of your life. To know that at any point, I can cause you immeasurable suffering and pain with the slightest show of effort on my part. THAT is what I live for. So you can be the most influential being for every person's life who ever existed, and you choose to make it miserable? Not exactly a way to win friends. -But you're wrong. I've created factions of allies that bring dimensions to their proverbial knees! Until you, what, give them a thermonuclear wedgie? That's what the history books will say. Eobard Thawne, the person who created a black hole constructed out of his own spite and misery. -You do realize that with what you're proposing, there would BE no history books, because I would have wiped out recorded history by definition of Do you have an off switch for that? -My genius? No, unfortunately for you, I don't. Then why don't you find someone else to bounce your evil plans off of? I'm too ethical to help you make things worse for yourself. -*pause* Come again? Ever heard of mimetic thinking? It's the idea that an individual's goals in life are constantly shaped by the goals they've observed set by others. We're unique in our existence, but not in our shared outcomes. You already determined one failpoint, whoever you were talking about -Barry. His name's Barry *dismissive for once* whatever. The point is, you must have gotten this idea, somewhere, from someone, that destroying everything is a positive. But the lack of anything is sure to be a negative when there's nothing left. Will you just do it again? Are you so unoriginal that you just want to run a time loop hamster wheel? -You are NOT getting away with comparing me to a hamster on a wheel, just because I use a treadmill to guide the fate of the universe! I didn't even…uh…wow. That's um…that's a…thing, I guess -You don't even know your own argument. You're bluffing! This is beyond trivial. Hey, you said that at some point, YOU told yourself that talking to me was a good idea. I have no inkling WHY, because you're the self proclaimed genius with the speed to do it all whenever you want, and you make yourself trivial in the process. I don't think you're capable of relating anymore. At least not with someone like me. Go find my evil doppleganger or something in another dimension, I don't know. -*evil laugh* YES! You stupid, foolish brilliant doctor! That makes sense. There must be a negative version of you.I just have to find him. He will unlock the last mysteries of my negative speedforce forever! But I needed you to tell me that. Wait! I *zoom sound, door shut* I guess I should be glad he took the “evil dimensional twin” comment and not the nuclear wedgie one. *more zooming, then door knocking* Um, come in. -*heavy breathing* Hello Mr. Thawne, I'm Dr. Issues. Hmm…you seem out of breath - *heavy breathing* It took a lot for me to get here. But *interrupting* It's still me, Eobard. I think you've got yourself stuck somehow. -*pause* How…I know this is Barry somehow. It has to be. It's his ultimate prank on me. He's getting me back! I'm forced to listen to an incompetent shrink until I find a way out! Hey!…or…ORRRRR…you could try doing some positive coping activities that open your mind so that you end up with a sense of gratitude for what you have, which will lead to better things in the future. Huh/ Huuuuuh? You ever think of that? You're stuck with me until you get it right anyway. -Oh for the love of…how about if I shortcut this whole thing to the end and tell myself that you are worth talking to so we can all get along and I can move on to wrecking Barry's life again. Deal? Isn't that just -Don't care, I'm doing it. Goodbye, Doctor *zoom* Ending (60:22) Recommended reading: Flash: Rebirth Next episodes: Aquaman, Echo, Speedball Plugs for social & GonnaGeek Network References: Timey-wimey ball - Anthony (8:44) Imitute it exarctly - Doc (20:40) “Why do you assume you're the smartest in the room?” - Doc (24:02) “I arranged the menu, the venue, the seating” - Doc (25:40) I Have No Mouth and I Must Scream - Anthony (39:18) Planet of the Apes Simpsons - Anthony (63:04) Apple Podcasts: here Google Play: here Stitcher: here TuneIn: here iHeartRadio: here Twitter Facebook TikTok Patreon TeePublic Discord
In this podcast episode, Dr. Tim Jackson and Dr. Joe Diduro discuss the benefits of light therapy for brain health. They explore how different wavelengths of light can have specific effects, such as red light for dilation and infrared light for neuroprotection. Dr. Diduro explains how photobiomodulation, particularly intranasal, can reduce neuroinflammation and improve sympathetic tone and relaxation. They also discuss the importance of good mitochondrial function and the role of the lymphatic system in brain health. Dr. Diduro shares his personal experience with light therapy, emphasizing its positive impact on his brain function and decision-making. To connect with Dr. Joe DiDuro, read the EPISODE TRANSCRIPT, links mentioned in today's episode, and more, visit: https://healyourbody.org/shedding-light-on-brain-health-an-exploration-of-transcranial-photobiomodulation-with-dr-joe-diduro-d-c/
New developments in the treatment of mental health challenges have been painfully slow to arrive. Talk therapy, lithium, prozac, electroshock therapy have all developed in the past 150 years. There have been a number of new medications developed but each has its own profile of positive and negative benefits. And few are highly effective (i.e., help more than 50% of the population they are intended to serve). In the past 10 years, however, there have been some noticeable improvements from some unsuspecting sources. These include psilocybin, ketamine, vagal nerve stimulation, Transcranial magnetic stimulation (TMS), Electroconvulsive therapy (ECT) and MDMA. Tune in to this fascinating conversation with Dr. Rebecca Allen, who heads up the Seattle Neuropsychiatric Treatment Center which is comprised of 5 treatment centers throughout Washington. Recent research out of Johns Hopkins, published in the prestigious journal Nature, found that critical windows of learning were re-opened in mice for 2,3 and 4 weeks depending on which psychedelic drug they were administered (and no, I have no idea how you discover the proper dosage of psilocybin for a mouse!). The mice were given either ketamine, MDMA, psilocybin, LSD or ibogaine. Ketamine kept the social reward learning period active for 48 hours, psilocybin and MDMA opened the critical learning window for two weeks, LSD for 3 weeks and ibogaine opened it for four weeks. This duration aligns loosely with the self-reported after effects of each psychedelic drug in humans. This post-treatment period could offer a valuable window of opportunity for maintaining the learning state. It appears that these drugs impact the RNA and thus, the genetic level, turning on or off genes associated with social learning. So these drugs seem to be impacting at a spiritual level, an interpersonal level, a cognitive level, a neurological level and at a genetic level. It is research such as this (as well as research in larger mammals, i.e., humans) that has heralded a new age in the treatment now called the Psychedelic Renaissance. Topics Covered In This Episode:Transcranial magnetic stimulation (TMS). For which mental health diagnoses is this treatment used? What is its efficacy?Electroconvulsive therapy (ECT). For which mental health disorders is this prescribed? What is its rate of success?Ketamine therapy. For what has it been shown to be helpful? Effectiveness rates?Psilocybin (magic mushrooms). What disorders show promising results here? What percentage of the population responds positively to them?Vagal nerve stimulation (VNS). What does this help?MDMA (Street names: ecstasy or molly). What about the recent excitement around MDMA for healing? What disorders are responsive to MDMA? About Dr. John's Esteemed Guest - Dr. Rebecca Allen:Dr. Allen is, among many other things,…Partner & Director of Neuropsychiatry and Research at the Seattle Neuropsychiatric Treatment Center Clinical Assistant Professor at the University of Washington Vice President of the Clinical TMS Society and Past President of theWashington State Psychiatric AssociationFind out more at https://seattlentc.com.If you like what you've heard at The Evolved Caveman podcast, support us by subscribing, leaving reviews on Apple podcasts. Every review helps to get the message out! Please share the podcast with friends and colleagues.
Kyle Hartfield, Transcranial Magnetic Stimulation (TMS)A Southern Californian Native. While seeking a better way to help those suffering from addiction he was introduced to TMS. While fighting with the State and Insurance companies trying to utilize a TMS machine inside of his Residential Drug and Alcohol Facility, his best friend of 30+ years took his own life. Dealing with the overwhelming pain of this tragedy, Kyle first turned to drugs and alcohol and then TMS.Today, Kyle owns and operates Inland Empire TMS and started a YouTube channel ITalkTMS.https://inlandempiretms.com/ (https://inlandempiretms.com/)tps://www.youtube.com/channel/UCtw_BGSUByu17wesiEpvstwLINKS:https://nonprofitarchitect.org/combat-vet-vision/https://www.facebook.com/iconutilityservices/photos/pcb.3282304212030773/3282304082030786/https://www.youtube.com/channel/UCqvd5sUEtC9xkm7ejGNK5Zw/featuredhttps://www.facebook.com/aqseiberthttps://www.facebook.com/CombatVetVisionEmail: Aqseibert@yahoo.comThe Warrior Built Foundation - https://warriorbuilt.org/The PTSD Foundation of America - https://ptsdusa.org/Virtual Office(Come see me) Virbella.comSponsorsSitch Radio - https://sitchradio.com/If you would like to become a sponsor or advertiser Call Sitch Radio (714) 643-2500 X 1Be part of the solution or the problem.PTSD FOA Warrior Group Chaptershttps://ptsdusa.org/about-us/chapters/
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.08.01.551431v1?rss=1 Authors: Misselhorn, J., Fiene, M., Radecke, J.-O., Engel, A. K., Schneider, T. R. Abstract: Attentional control over sensory processing has been linked to neural alpha oscillations and related pulsed inhibition of the human cortex. Despite the wide consensus on the functional relevance of alpha oscillations for attention, precise neural mechanisms of how alpha oscillations shape perception and how this top-down modulation is implemented in cortical networks remain unclear. Here, we tested the hypothesis that alpha oscillations in premotor cortex are causally involved in top-down regulation of visual cortex responsivity to contrast. We applied intermittent transcranial alternating current stimulation (tACS) over bilateral premotor cortex to manipulate attentional preparation in a visual discrimination task. tACS was applied at 10 Hz (alpha) and controlled with 40 Hz (gamma) and sham stimulation. Importantly, we used a novel linear mixed modeling approach for statistical control of neurosensory side-effects of the electric stimulation. We found a frequency-specific effect of alpha tACS on the slope parameter, leading to enhanced low-contrast perception and decreased perception of high-contrast stimuli. Side-effects affected both threshold and slope parameters, leading to high variability in parameter estimates. Controlling the impact of side-effects on psychometric parameters by linear mixed model analysis reduced variability and clarified the existing effect. We conclude that alpha tACS over premotor cortex mimicked a state of increased endogenous attention potentially by modulation of fronto-occipital connectivity in the alpha band. We speculate that this network modulation allowed for improved sensory readout from visual cortex which led to a decrease in psychometric slope, effectively broadening the dynamic range for contrast perception. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
In this episode, host Dr. Jacob Fleming interviews one of his attendings Dr. Bhavya Shah about the remarkable features of focused ultrasound technology and its applications. They discuss its dynamic nature, allowing for a wide range of applications. --- SHOW NOTES Dr. Bhavya Shah is a neuroradiologist at UT Southwestern in Dallas, TX and the director of their transcranial-focused ultrasound lab. While in residency at Boston MIT, he studied the radiology applications for nerve regeneration and expanded his scope of practice during his fellowship at Stanford. Dr. Bhavya Shah explains the use of low intensity focused ultrasound (LIFU) and high intensity focused ultrasound (HIFU), particularly in the context of movement disorders including essential tremor and Parkinson's disease. LIFU is used to identify the appropriate targets in the brain in relation to the disease and may be used to alter how neurons behave. In contrast, high intensity focused ultrasound (HIFU) is utilized to ablate and destroy tissues typically after the localization of the intended treatment area. Dr. Shah developed a way to identify targets in the brain for treatment with focused ultrasound with the use of four-tract tractography in cadavers. Using this technology, the brain can be thinly sliced into sections which could then be registered off an MRI back to the path using block face photography, allowing the identification of white matter tracts that enter and leave the thalamus. With these tracts identified, neuroradiologists can first stimulate the localized area with LIFU to confirm the location, then ablate using HIFU. The procedure lasts approximately 30-45 minutes as the patient remains awake. Remarkably, patients with essential tremor usually experience benefit immediately following the procedure as patients with Parkinson's have symptom improvement within days to weeks. After two hours of observation, patients are discharged assuming no side effects. Side effects are uncommon but can include numbness and tingling around the mouth or fingertips as well as muscle weakness. Beyond its use for movement disorders, the adaptable nature of focused ultrasound technology shows promise for a broad range of applications, particularly for the use of neuropsychiatric conditions. Dr. Shah offers the potential for the use of HIFU as a wearable device that delivers constant stimulation modulated by biofeedback, potentially eliminating the need for MRI for the procedure. Dr. Shah and Dr. Fleming end the discussion with how radiology has evolved over the years and the importance of keeping an open mind working in a multidisciplinary team. They emphasize the gravity of patient engagement and the central goal of medicine and improving the standard of care should always be aimed at benefiting the patient. --- RESOURCES MRI–Guided Focused Ultrasound Thalamotomy for Essential Tremor: https://thejns.org/view/journals/j-neurosurg/138/4/article-p1028.xml Trial of Globus Pallidus Focused Ultrasound Ablation in Parkinson's Disease: https://www.nejm.org/doi/10.1056/NEJMoa2202721 Long-term effects of bilateral subthalamic nucleus deep brain stimulation on gait disorders in Parkinson's disease: a clinical-instrumental study https://pubmed.ncbi.nlm.nih.gov/37208527/ Magnetic Resonance Image Guided Focused Ultrasound Thalamotomy. A Single Center Experience With 160 Procedures: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894664/
In this episode, host Dr. Jacob Fleming interviews one of his attendings Dr. Bhavya Shah about the remarkable features of focused ultrasound technology and its applications. They discuss its dynamic nature, allowing for a wide range of applications. --- SHOW NOTES Dr. Bhavya Shah is a neuroradiologist at UT Southwestern in Dallas, TX and the director of their transcranial-focused ultrasound lab. While in residency at Boston MIT, he studied the radiology applications for nerve regeneration and expanded his scope of practice during his fellowship at Stanford. Dr. Bhavya Shah explains the use of low intensity focused ultrasound (LIFU) and high intensity focused ultrasound (HIFU), particularly in the context of movement disorders including essential tremor and Parkinson's disease. LIFU is used to identify the appropriate targets in the brain in relation to the disease and may be used to alter how neurons behave. In contrast, high intensity focused ultrasound (HIFU) is utilized to ablate and destroy tissues typically after the localization of the intended treatment area. Dr. Shah developed a way to identify targets in the brain for treatment with focused ultrasound with the use of four-tract tractography in cadavers. Using this technology, the brain can be thinly sliced into sections which could then be registered off an MRI back to the path using block face photography, allowing the identification of white matter tracts that enter and leave the thalamus. With these tracts identified, neuroradiologists can first stimulate the localized area with LIFU to confirm the location, then ablate using HIFU. The procedure lasts approximately 30-45 minutes as the patient remains awake. Remarkably, patients with essential tremor usually experience benefit immediately following the procedure as patients with Parkinson's have symptom improvement within days to weeks. After two hours of observation, patients are discharged assuming no side effects. Side effects are uncommon but can include numbness and tingling around the mouth or fingertips as well as muscle weakness. Beyond its use for movement disorders, the adaptable nature of focused ultrasound technology shows promise for a broad range of applications, particularly for the use of neuropsychiatric conditions. Dr. Shah offers the potential for the use of HIFU as a wearable device that delivers constant stimulation modulated by biofeedback, potentially eliminating the need for MRI for the procedure. Dr. Shah and Dr. Fleming end the discussion with how radiology has evolved over the years and the importance of keeping an open mind working in a multidisciplinary team. They emphasize the gravity of patient engagement and the central goal of medicine and improving the standard of care should always be aimed at benefiting the patient. --- RESOURCES MRI–Guided Focused Ultrasound Thalamotomy for Essential Tremor: https://thejns.org/view/journals/j-neurosurg/138/4/article-p1028.xml Trial of Globus Pallidus Focused Ultrasound Ablation in Parkinson's Disease: https://www.nejm.org/doi/10.1056/NEJMoa2202721 Long-term effects of bilateral subthalamic nucleus deep brain stimulation on gait disorders in Parkinson's disease: a clinical-instrumental study https://pubmed.ncbi.nlm.nih.gov/37208527/ Magnetic Resonance Image Guided Focused Ultrasound Thalamotomy. A Single Center Experience With 160 Procedures: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894664/
Transcranial magnetic stimulation (TMS) is a technology that uses magnetic fields to stimulate or suppress electrical activity in brain circuits. It's part of a transformation in how psychiatrists are thinking about mental health disorders that today's guest calls psychiatry 3.0. Nolan Williams has recently pioneered a new form of TMS therapy that has just been approved by the FDA to treat patients with treatment-resistant depression. That actually describes a lot of people with serious depression — somewhere between a third to a half. At some point talk therapy doesn't work, drugs don't work, and for most people, there's not much else to try. TMS has been used for depression before, but Williams' team has taken a new, more targeted approach. It's called SAINT, which stands for Stanford Accelerated Intelligent Neuromodulation Therapy. Basically, it uses MRI brain imaging to precisely target intensive TMS stimulation to tweak the function of specific circuits in each patient's brain. Remarkably, after just one week in Williams' SAINT trial, 80% of patients went into full remission. The stories these patients tell about the impact this has had on their lives are incredible. We talked to Williams, who is a faculty director of the Koret Human Neurosciences Community Laboratory at Wu Tsai Neuro, about what makes this approach unique and what it means for the future of psychiatry.Additional ReadingResearchers treat depression by reversing brain signals traveling the wrong way (Stanford Medicine)FDA Clears Accelerated TMS Protocol for Depression (Psychiatric News)Experimental depression treatment is nearly 80% effective in controlled study (Stanford Medicine)An experimental depression treatment uses electric currents to bring relief (NPR) Jolting the brain's circuits with electricity is moving from radical to almost mainstream therapy. Some crucial hurdles remain (STAT News)Episode CreditsThis episode was produced by Webby award-winning producer Michael Osborne, with production assistance by Morgan Honaker, and hosted by Nicholas Weiler. Art by Aimee Garza.Thanks for listening! Learn more about the Wu Tsai Neurosciences Institute at Stanford and follow us on Twitter, Facebook, and LinkedIn.
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.05.03.539327v1?rss=1 Authors: Fujiyama, H., Williams, A. G., Tan, J., Levin, O., Hinder, M. R. Abstract: Background: The efficacy of transcranial alternating current stimulation (tACS) is thought to be brain state-dependent, such that tACS during task performance would be hypothesised to offer greater potential for inducing beneficial electrophysiological changes in the brain and associated behavioural improvement compared to tACS at rest. However, to date, no empirical study has directly tested this postulation. Objective: Here we compared the effects of tACS applied during a stop signal task (online) to the effects of the same tACS protocol applied prior to the task (offline) and a sham control stimulation. Methods: A total of 53 young, healthy adults (32 female; 18-35 yrs) received dual-site beta tACS over the right inferior frontal gyrus (rIFG) and pre-supplementary motor area (preSMA), which are thought to play critical roles in action cancellation, with phase-synchronised stimulation for 15 min with the aim of increasing functional connectivity. Results: EEG connectivity analysis revealed significantly increased task-related functional connectivity following online but not offline tACS. Correlation analyses suggested that an increase in functional connectivity in the beta band at rest following online tACS was associated with an improvement in response inhibition. Interestingly, despite the lack of changes in functional connectivity at the target frequency range following offline tACS, significant improvements in response inhibition were still observed, suggesting offline tACS may still be efficacious in inducing behavioural changes, likely via a post-stimulation early plasticity mechanism. Conclusion: Overall, the results indicate that online and offline dual-site beta tACS are beneficial in improving inhibitory control via distinct underlying mechanisms. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.04.26.538484v1?rss=1 Authors: Henderson, T. T., Taylor, J. L., Thorstensen, J. R., Kavanagh, J. J. Abstract: Serotonin modulates corticospinal excitability, motoneurone firing rates and contractile strength via 5-HT2 receptors. However, the effects of these receptors on cortical and motoneurone excitability during voluntary contractions have not been explored in humans. Therefore, the purpose of this study was to investigate how 5-HT2 antagonism affects corticospinal and motoneuronal excitability with and without descending drive to motoneurones. Twelve individuals (aged 24 {+/-} 4 years old) participated in a double-blind, placebo-controlled, crossover study, whereby the 5-HT2 antagonist cyproheptadine was administered. Transcranial magnetic stimulation (TMS) was delivered to the motor cortex to produce motor evoked potentials (MEPs) and electrical stimulation at the cervicomedullary junction was used to generate cervicomedullary motor evoked potentials (CMEPs) in the biceps brachii at rest and during a range of submaximal elbow flexions. Evoked potentials were also obtained after a conditioning TMS pulse to produce conditioned MEPs and CMEPs (100 ms inter-stimulus interval). Compared to placebo, 5-HT2 antagonism reduced maximal elbow flexion torque (p = 0.004), unconditioned MEP amplitude at rest (p = 0.003), conditioned MEP amplitude at rest (p = 0.033), and conditioned MEP amplitude during contractions (p = 0.020). 5-HT2 antagonism also increased unconditioned CMEP amplitude during voluntary contractions (p = 0.041) but not at rest. Although 5-HT2 antagonism increased long-interval intracortical inhibition, net corticospinal excitability was unaffected during voluntary contractions. Given that spinal motoneurone excitability was only affected when descending drive to motoneurones was present, the current study indicates that excitatory drive is necessary for 5-HT2 receptors to regulate motoneurone excitability but not intracortical circuits. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Transcranial magnetic stimulation (TMS) has been a treatment option for people with major depression since it was approved by the FDA in 2008. Today, it is also used to treat obsessive compulsive disorder and anxiety and for smoking cessation. Sarah “Holly” Lisanby, MD, director of the Noninvasive Neuromodulation Unit at the National Institute of Mental Health, talks about how TMS works and recent advances in TMS treatment, as well as other brain stimulation treatments such as electroconvulsive therapy. Writer Diana Daniele also offers her perspective on how TMS helped her overcome treatment-resistant depression. For transcripts, links and more information, please visit the Speaking of Psychology Homepage.
New research shows that you can treat COVID-19 brain fog with red light therapy by either treating the brain directly OR by doing full-body treatments. How cool is that?! On this week's solosode of The Red Light Report, we will dig into three separate photobiomodulation articles that cover an array of topics and continue to add to the depth of our understanding of red light therapy's potential and, equally important, its potential limitations. As I eluded to above, the first article I will report on comes from one of our good friends and former podcast guests, Praveen Arany, on how brain fog secondary to COVID-19 can be treated with red light therapy either transcranially or via full-body treatments. That's awesome to know, as that gives us options and some flexibility en route to positive benefits for this health malady; as far as I'm concerned, it's nice to have options!The second article is for the women out there and/or those that work in the women's health field: transvaginal red light therapy in order to help reduce pain related to interstitial cystitis/ bladder pain syndrome. For many of you, this may be the first time you have heard about red light therapy inside the vagina. However, this type of a treatment has been an option for women for quite some time with many potential health benefits. This is just the first time I have reported on it on the podcast.The last article is about red light therapy and its potential with treating skin cancer. There is a decent amount of overlap with the article we covered last week on RLT and cancer, but it's always great to hear the information from a slightly different vantage point and different researchers. It's nice to cover several topics in a single episode to help convey red light therapy's many potentials and versatility. At the very least, it goes to show that darn near anyone and everyone can benefit from a little red light therapy in their lives. As always, light up your health and enjoy! - Dr. Mike Belkowski discusses the following: Intro: (0:00) Get 15% off The Glow - BioLight's new handheld device (limited time only): (1:33) COVID-19 brain fog and photobiomodulation: (2:32) Women's health: transvaginal photobiomodulation: (14:03) Skin cancer and photobiomodulation: (21:56) Near-infrared and melanoma: (26:10) - Research article from the episode: Use of either Transcranial or Whole-Body Photobiomodulation Treatments improves COVID-19 Brain Fog Transvaginal Photobiomodulation Improves Pain in Women with Pelvic Muscle Tenderness and Interstitial Cystitis/Bladder Pain Syndrome: A Preliminary Observational Study Responses of melanoma cells to photobiomodulation depend on cell pigmentation and light parametersLearn more about these topics and on how RLT can be beneficial:Brain & Cognitive Health Women's Health Skin Health - Check out BioLight's newest device: the Glow! - Check out the Kindle version of Red Light Therapy Treatment Protocols eBook, 4th Edition - To learn more about red light therapy and shop for the highest-quality red light therapy products, visit https://www.biolight.shop - Stay up-to-date on social media: Dr. Mike Belkowski: Instagram LinkedIn BioLight: Instagram YouTube Facebook
Mohammed Milad, PhD, discusses recent research into fear conditioning, regulation, and extinction. Dr. Milad is a Professor in the Department of Psychiatry at the NYU Grossman School of Medicine and Director of the Behavioral Neuroscience Program.Topics covered:Transcranial magnetic stimulation (TMS)Estrogen and PTSDPost-traumatic stress disorder (PTSD)MeditationDeep brain stimulationVisit our website for more insights on psychiatry.Podcast producer: Jon Earle
On this week's episode of The Red Light Report, I will peel back the curtain on BioLight's newest piece of innovative red light therapy technology: the Adapt System. Many of you likely heard about it when it was officially released a couple of months ago, but I wanted to give an explanation of what makes the Adapt System, which consists of the Adapt Table and the Adapt Panel, so unique, versatile and a must-have for any physician/practitioner, longevity clinic, med spa, recovery/performance center, yoga studio/cross fit gym, etc. that is looking to implement red light therapy for their patients and clients. After that, we will spend the bulk of the episode on one piece of photobiomodulation research that looks at transcranial RLT for treating the brains of four ex-football players with possible chronic traumatic encephalopathy, or CTE. And CTE has become a very hot topic in the NFL, especially ever since the movie, Concussion (starring Will Smith), was released back in 2015. However, the concern regarding CTE in football, other sports and other aspects of life has only grown and remains ever-present to this day.It is also appropriate to recognize that this particular study utilized only four participants, which is very low in the world of research. However, even with that in mind, the results ascertained in this study simply by directing near-infrared light to the brain is unequivocally profound... and the results were achieved in only six weeks!Hopefully you find this episode fascinating and insightful. As always, light up your health (especially your brain)! - Dr. Mike Belkowski discusses the following: 0:16 - The Adapt System - BioLight's new, cutting-edge full-body product 8:33 - Photobiomodulation research on treating concussions 9:40 - CTE disease 15:09 - Treating strokes with photobiomodulation 16:12 - LED vs laser treatment 18:57 - Reactive oxygen species and free radicals 19:29 - How often to use red light therapy 25:12 - Less irratibility & anxiety 26:20 - Transcranial photobiomodulation treatment 27:20 - Increased BDNF 27:46 - Treatment of PTSD 38:31 - The conclusion of the article _ Research article from the episode:Transcranial Photobiomodulation Treatment: Significant Improvements in Four Ex-Football Players with Possible Chronic Traumatic Encephalopathy - Learn more about RLT's benefits for: Brain & Cognitive Health - Check out BioLight's new, cutting-edge full-body product: The Adapt System _ Save 20% via BioLight Bundles all year long! _ Check out the Kindle version of Red Light Therapy Treatment Protocols eBook, 4th Edition _ To learn more about red light therapy and shop for the highest-quality red light therapy products, visit https://www.biolight.shop _ Stay up-to-date on social media: Instagram
Link to bioRxiv paper: http://biorxiv.org/cgi/content/short/2023.02.22.527901v1?rss=1 Authors: Kop, B. R., Shamli Oghli, Y., Grippe, T. C., Nandi, T., Lefkes, J., Meijer, S. W., Farboud, S., Engels, M., Hamani, M., Null, M., Radetz, A., Hassan, U., Darmani, G., Chetverikov, A., den Ouden, H. E. M., Bergmann, T. O., Chen, R., Verhagen, L. Abstract: Transcranial ultrasonic stimulation (TUS) is rapidly emerging as a promising non-invasive neuromodulation technique. TUS is already well-established in animal models, and now stimulation protocols that optimize neuromodulatory efficacy for human application are required. One promising protocol, pulsed at 1000 Hz, has consistently resulted in motor cortical inhibition. At the same time, a parallel research line has highlighted the potentially confounding influence of peripheral auditory stimulation arising from pulsing TUS at audible frequencies. Across four experiments, one preregistered, at three independent institutions, we employed tightly matched control conditions to disentangle direct neuromodulatory effects of TUS from those driven by the salient auditory confound in a combined transcranial ultrasonic and magnetic stimulation paradigm. We replicated motor cortical inhibition following TUS, but showed through both controls and manipulation of stimulation intensity, duration, and auditory masking conditions that this inhibition was driven by peripheral auditory stimulation rather than direct neuromodulation. This study highlights the substantial impact of the auditory confound, invites a reevaluation of prior findings, and calls for appropriate control conditions in future TUS work. Only when direct effects are disentangled from those driven by peripheral confounds can TUS fully realize its potential for neuroscientific research and clinical applications. Copy rights belong to original authors. Visit the link for more info Podcast created by Paper Player, LLC
Ep135There are many controversial topic that divide the bigfoot community but none so much as the “mind speak” phenomena. Experiencers claim that the creature they identify as bigfoot somehow communicates with them via telepathic means. To both proponents of the flesh and blood theory and the paranormal theory these claims have been challenged. But what if we are confusing another phenomena for bigfoot, what if we are misinterpreting these encounters with something other? This is a highly speculative episode, views expressed are our own, we invite everyone to keep and open mind and draw your own conclusions. Join us as we look at the strange phenomena of mind speak.Watch it here:https://youtu.be/R4LC30-iuUkDr Persinger:https://en.wikipedia.org/wiki/Michael_Persingergod helmet:https://en.wikipedia.org/wiki/God_helmetTranscranial magnetic stimulation:https://en.wikipedia.org/wiki/Transcranial_magnetic_stimulationThe Neuropsychiatry of Paranormal Experiences PDFhttps://neuro.psychiatryonline.org/doi/pdf/10.1176/jnp.13.4.515?download=trueCommunication wit ET Intelligence:https://www.nsa.gov/portals/75/documents/news-features/declassified-documents/cryptologic-spectrum/communications_with_extraterrestrial.pdf
Have you ever seen me wearing a crazy, laser-light helmet on my head, with red-flashing nasal probes shoved into my nostrils, and thought... ..."What the heck is that, and why would someone ever choose such a horrific fashion statement?" But stick with me here because there's actually something to the science of this so-called use of "photobiomodulation." A lot of something and a lot of science. The basis of all your thoughts, behavior, and emotions is the communication between your neuronal networks. This interaction leads to the formation of neural electrical signals known as brainwaves. Brain stimulation via photobiomodulation stimulates neuronal mitochondria, which increases cellular energy levels. This results in improved efficiency in neural signaling and communication. The "helmet" red light technology I wear - which I don three to four times per week for 25 minutes - is the first in the world to demonstrate the ability to modulate and alter brainwaves using NIR electromagnetic (light) energy, measured through EEG. Delivering pulsed near-infrared (NIR) light energy into the brain's Default Mode Network (DMN) upgrades brain capability, increases longevity, and improves physiological health. Microchip-boosted cold LED diodes in this setup - made by a company called "Vielight" (use code GREENFIELD to save 10%) - can safely maximize energy transmission into the brain, and intranasal photobiomodulation technology is used for ventral brain stimulation. Transcranial-intranasal systems like this enable comprehensive, non-invasive, and safe brain photobiomodulation. Visit https://bengreenfieldfitness.com/vielight for more info. Show notes for this episode: https://bengreenfieldlife.com/lewlim Episode Sponsors: Naboso: Naboso features sensory-based product lines, created for athletes, fitness enthusiasts, and biohackers as a way to optimize their foot health and foot recovery. Better movement begins now. Visit naboso.com/ben and use code BEN for 10% off. Fresh Pressed: The world's most delicious artisanal olive oils, direct from gold-medal-winning small farms, right at harvest time when the oils' flavor and nutrients are at their peak! Try a bottle for just $1 and taste the difference yourself. Just go to GetFresh38.com BioStack Labs: BioStack Labs have formulated their NAD Regen to increase your energy, enhance your cognitive function, and slow the aging process. Buy 2 NAD Regen for $134 and get 1 FREE (worth $67!) at BioStackLabs.com/Ben. BiOptimizers (Nootopia): Nootopia has some of the most powerful, customizable nootropics on the market today. Go to nootopia.com/ben and use ben10 to receive up to 10% off any order. HVMN: Visit hvmn.me/BenG and use code BENG20 for 20% off any purchase of Ketone-IQ️. This is an exclusive offer for podcast listeners. Six Senses Event: Join me in this beautiful 19th-century wine estate in Portugal and enjoy treatments that go beyond the ordinary in Six Senses Spa. Ten treatment rooms and an indoor pool with chromotherapy and an underwater sound system offer a unique and layered wellness experience. Try delicious food made with local sensitivity and global sensibility. Head over to bengreenfieldlife.com/sixsenses and claim your spot today.
Listen in as Dr. Rountree discusses new research that shows that near-infrared light therapy might improve anxiety, mood, energy, daily routine, sleep, and cognition while reducing the burden on caregivers. Access the full study here.We do a live broadcast of the LTI Podcast every other week on Facebook. Watch this episode here. (Be sure to catch our Healing at the Speed of Light Podcast on Facebook as well!)YouTube ChannelLaser Therapy InstituteFurther Resources:Success with Laser Therapy Flowchart & Checklist InfographicCheck out these FREE Provider ResourcesRead about laser research on the LTI BlogLearn more about what we offer on the LTI websiteFind out how you can Customize your LTI experienceRelated Podcast for PatientsHealing at the Speed of Light
This week on The Red Light Report, we have two more remarkable pieces of photobiomodulation research to cover and, to top it off, both are figuratively hot-off-the-press — being published only this past summer! You've heard me say it before, but I'll say it again... while the information may be on particular topics, the takeaways are far-reaching and can be applicable to virtually everyone. The first article covered has to do with the ability for red light therapy to improve the tissue regeneration capabilities of fibrin application. Who doesn't want more effective and efficient wound healing and tissue/organ healing? The second piece of research is especially interesting, as it has to do with red light therapy's impact on the brain. However, the article goes even deeper and analyzes the benefits of photobiomodulation temporally, meaning the therapeutic affects it has during wakefulness versus asleep. Needless to say, they have some interesting speculations as to how near-infrared light can impact the brain during sleep that has potentially profound implications for the glymphatic system. This new research continues to expand our awareness on some exciting, novel utilities of red light therapy that can positively impact our health. As always, light up your health and enjoy this solosode! - Dr. Mike Belkowski discusses the following: 1:43 - Yoga red light therapy 2:49 - Therasage 5:41 - Improving regeneration in tissue via photobiomodulation 8:34 - Fibrin and photobiomodulation 9:10 - Management of the healing process via photobiomodulation 12:34 - Gold nanoparticles 13:31 - The effect of photobiomodulation during wakefulness and sleep 18:54 - Photobiomodulation influences functional activity 23:32 - Increasing mitochondrial activity 26:29 - Photobiomodulation and sleep 31:16 - Transcranial photobiomodulation 32:17 - Photobiomodulation mechanisms during sleep 35:52 - Mornings vs Day/ night for Increasing mitochondrial function and ATP levels 37:33 - Anti-inflammatory effects during sleep 43:40 - How to use near-infrared light while sleeping - Research articles: Application of Fibrin Associated with Photobiomodulation as a Promising Strategy to Improve Regeneration in Tissue Engineering: A Systematic Review The effect of photobiomodulation on the brain during wakefulness and sleep - Check out the newest innovative device from BioLight... the Matrix! - Check out the Kindle version of Red Light Therapy Treatment Protocols eBook, 4th Edition - To learn more about red light therapy and shop for the highest-quality red light therapy products, visit https://www.biolight.shop - Stay up-to-date on social media: Instagram
Weronika Potok and Nicole Wenderoth discuss their paper, “Transcranial Random Noise Stimulation Acutely Lowers the Response Threshold of Human Motor Circuits,” published in Vol. 41, Issue 17 of The Journal of Neuroscience, with Editor-in-Chief Marina Picciotto. Find our upcoming webinar schedule here. With special guests: Weronika Potok and Nicole Wenderoth Hosted by: Marina Picciotto On Neuro Current, we delve into the stories and conversations surrounding research published in the journals of the Society for Neuroscience. Through its publications, JNeurosci, eNeuro, and the History of Neuroscience in Autobiography, SfN promotes discussion, debate, and reflection on the nature of scientific discovery, to advance the understanding of the brain and the nervous system. Find out more about SfN and connect with us on Twitter, Instagram, and LinkedIn.
My guest, Rico Petrini, was a top defensive player in the country as a linebacker at Oregon State University in the 90's. I connected with Rico in the Facebook support group CTE & Brain Injury Global Support - https://www.facebook.com/groups/164998687455984 In this interview, Rico discusses his numerous concussions, unsafe training practices, and the desire to play through any pain or medical problem. It was over two decades later that his TBI/CTE symptoms reared their head, a cascade of awful symptoms that were kicked off by a very stressful moment in his life. Fortunately, Rico was proactive and began doing anything he could that might help. He volunteered for a study at the University of Utah TBI and Concussion Center, with 49 other football players where they used photobiomodulation, a type of light therapy. This treatment turned Rico's life around and although he will never be the person he once was, he is in such a better place and making a difference helping others with their struggles. We talk about the importance of not fighting CTE or any struggle on your own and how important it is to be part of a supportive group. He also has put together the non-proft 4CTE by CTE which is in its early stages. Includes the short story "Going Dark" taken from Somber Stroll and narrated by Tee Quillin. Here is an article on the Light study - https://www.concussionalliance.org/blog/2022/1/25/light-therapy-study-at-the-university-of-utah
In this week's solosode of The Red Light Report, we will cover two more exciting and important topics in the 4th edition of the Red Light Therapy Treatment Protocols eBook. We will take a dive into Inflammation and Nerve Injuries, covering relevant information on how red light therapy can help each condition along with new, pertinent photobiomodulation research on each topic. Rest assured, you will walk away with a healthier respect for how red light therapy, when implemented appropriately, can be a powerful tool for both circumstances. On the previous solosode, we covered the following topics in the eBook: Hair Health, Heart Health & the Immune System. More exciting new red light therapy information and research is covered and should continue to open your eyes to the exciting potential of this healing modality. Light up your health and enjoy! - BioLight's website is soon to be revamped! - biolight.shop BioLight's brand new full-body red light therapy product 3:49 - Dr. Mike Belkowski will be speaking in Rome at a photobiomodulation symposium 4:49 - The three main mechanisms of photobiomodulation 9:10 - Anti-inflammatory effects of red light therapy 11:45 - Inflammation research 13:33 - Diabetic wound healing 16:06 - Reducing oxidative stress 17:26 - Reducing lung inflammation 18:48 - Reducing acute pain 22:01 - Transcranial photobiomodulation for brain inflammation 32:03 - Research on nerve injury 34:09 - Treating the facial nerve 34:58 - Physical therapy and red light therapy 40:46 - Treating nerve and muscle injury 44:07 - Management of severe nerve injury - Check out the Kindle version of Red Light Therapy Treatment Protocols eBook, 4th Edition - To learn more about red light therapy and shop for the highest-quality red light therapy products, visit https://www.biolight.shop - Stay up-to-date on social media: Instagram YouTube
This week we ask if it ever gets better and talk about Transcranial magnetic stimulation Paper: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993526/ Blog: nirzhor2002.wixsite.com/thinkcreateinspire Contact: seriouslyfunnypodcast@gmail.com Find Seriously Funny On Anchor Apple Podcasts Spotify Google Podcasts PocketCasts Breaker RadioPublic Overcast --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app Support this podcast: https://anchor.fm/seriouslyfunnypodcast/support
Who doesn't know someone dealing with depression, or maybe you are dealing with it right now? Treatment options can be frustrating and it can take a long time to get the help you need. In this episode we talk all things TMS transcranial magnetic stimulation for depression. YES! It can have other indications YES! You will get your questions answered on how this treatment might be right for you. We are talking what it is, how it works, who it's for, how well it works, how long it takes and so much more! This is such a fantastic episode and you will learn so much from Dr. Adam Stern. You will not want to miss this one! Info on The Well-Informed Patient Podcast: Apple Podcast: https://podcasts.apple.com/us/podcast/the-well-informed-patient-podcast/id1531533187 Spotify: https://open.spotify.com/show/2WtflmHho7DpI6qVr1fWTL?si=A-xAOlDfQMGPDq7q042wQg Direct download of The Well-Informed Patient Podcast and subscribe: https://thewellinformedpatientpodcast.libsyn.com/ How to find Dr. Stern: Follow Dr. Stern on Twitter Follow Dr. Stern on Instagram Book: Committed: Dispatches From A Psychiatrist In Training Dr. Stern's Podcast: Characters On The Couch
Parkinson's disease is a progressive neurodegenerative disease with no cure and few treatment options. Cases of Parkinson's disease have increased due to aging populations and longer disease duration. In this episode, Dr. Rountree and Kristi review a 2021 study on how laser and light therapy has been safely used to stimulate neural pathways in the brain. Transcranial light therapy has positive effects on the tissues of the brain; reducing inflammation of the brain and stimulating tissues at the cellular level to help develop new neural pathways. We have begun live-streaming this podcast. Watch this episode on Facebook right here, and see the next episode LIVE in two weeks!Mentioned in this episode:Improvements in clinical signs of Parkinson's disease using photobiomodulation: a prospective proof-of-concept studyVielightVisit the LTI website for more information and to find a laser therapy provider near you. Are you a healthcare provider?Laser Therapy Institute Podcast YouTube ChannelHealing at the Speed of Light
Children with Autism Spectrum Disorder (ASD) face several challenges due to deficits in social function and communication with distinct patterns of behaviors that can be difficult to manage and even disruptive. Laser and light therapy can be used for transcranial photobiomodulation to enhance mitochondrial activity and ATP synthesis, increasing functional activity and cognition. Listen along as Dr. Rountree and Kristi discuss a 2022 study on ASD and laser therapy, how the treatment was administered, what kind of side effects may occur and what the outcomes were for the ASD patients. Also, learn what steps you can take today to help your autistic child. We have begun live-streaming this podcast. Watch this episode on Facebook right here, and see the next episode LIVE in two weeks!Mentioned in this episode:Transcranial Photobiomodulation for the Treatment of Children with Autism Spectrum Disorder (ASD): A Retrospective Study.VielightVisit the LTI website for more information and to find a laser therapy provider near you. Are you a healthcare provider?Laser Therapy Institute Podcast YouTube ChannelHealing at the Speed of Light
The Sonography Lounge Hosts Lori and Trisha Talk with our guest Shannon York from Sky Vascular LLC to discuss Transcranial Doppler Ultrasound. They go into the many uses of the technology, facilities that can benefit from the integration of TCD, case studies, and more. Transcranial Doppler is a facet of vascular ultrasound that is gaining notoriety quickly. With advancements in ultrasound technology and proper training, TCD can now allow us to evaluate the blood flow in the brain without the use of harmful radiation or dye in ways that would previously not have been possible. Today we would like to give you a brief overview of TCD and several of its many applications that are helping to save lives through stroke prevention and treatment. Shannon York, BS, RVT, RDCS President of Clinical Education Clinical Applications & Education Specialist shannon@skyvascular.com 803-463-2155 skyvascular.com linkedin.com/in/skyvascular The American Society of Neuroimaging (ASN) - NVS Examination: https://www.asnweb.org/i4a/pages/index.cfm?pageid=4028 CME and Cross-training resources: Gulfcoast Ultrasound Institute (Training materials and programs): www.gcus.com Societies and Certification Agencies: International Accreditation Commission: https://intersocietal.org/ Society of Vascular Ultrasound: https://www.svu.org/ Society of Vascular Surgery: https://vascular.org/ American College of Radiology: https://www.acr.org/ Sonographer / Physician: American Registry of Diagnostic Medical Sonography (ARDMS): www.ardms.org Physicians: Alliance for Physician Certification & Advancement (APCA): www.APCA.org Point of Care Healthcare Providers: Point of Care Certification Academy (POCUS): www.pocus.org Sonographer / Physician: Cardiovascular Credentialing International (CCI): www.cci-online.org American Institute of Ultrasound in Medicine: https://www.aium.org/ Want to become a Sonographer? Find an accredited long term Ultrasound Program: https://www.caahep.org/Students/Find-a-Program.aspx
Depression remains a major problem in our society but now there is a new outpatient treatment for it called Transcranial magnetic stimulation, or TMS, therapy. Dr. Lou Ann Eads discusses TMS therapy and how it can help improve depression.
The Sonography Lounge Hosts Lori and Trisha dive get the low-down on new technology updates with Michael Talcott, Vice President of Sales with Image Monitoring USA, who is going to share a little bit more about the future of Transcranial Doppler (TCD). Image Monitoring USA: https://imagemonitoringusa.com/ Michael Talcott: mtalcott@imagemonitoring.com CME and Cross-training resources: Gulfcoast Ultrasound Institute (Training materials and programs): www.gcus.com Societies and Certification Agencies: International Accreditation Commission: https://intersocietal.org/ Society of Vascular Ultrasound: https://www.svu.org/ Society of Vascular Surgery: https://vascular.org/ American College of Radiology: https://www.acr.org/ Sonographer / Physician: American Registry of Diagnostic Medical Sonography (ARDMS): www.ardms.org Physicians: Alliance for Physician Certification & Advancement (APCA): www.APCA.org Point of Care Healthcare Providers: Point of Care Certification Academy (POCUS): www.pocus.org Sonographer / Physician: Cardiovascular Credentialing International (CCI): www.cci-online.org American Institute of Ultrasound in Medicine: https://www.aium.org/ Want to become a Sonographer? Find an accredited long term Ultrasound Program: https://www.caahep.org/Students/Find-a-Program.aspx
Dr. Katrina Ignacio discusses the emerging subspecialty of Transcranial Stimulation.
Are meds and talk therapy not getting the job done anymore? Host Dr. Grammer and Co-host Joe explore a different type of treatment for depression: Transcranial Magnetic Stimulation (TMS) therapy. Listen to this eye-opening podcast to learn about the science behind TMS and learn if it could work for you.
Narrator: Shobana Rajan, MD in conversation with Deepak Sharma, MBBS, MD, DM.