Podcasts about dq8

Even though we have a DQ movie already with YOUR STORY, we keep hearing from fans asking us about who we think should play in all sorts of movies. So we decided that this week we would give our dream fan casting for DQ8! Let us know what you think and who we got right and wrong and who you'd have in each role!Find us on Bluesky at https://bsky.app/profile/dragonquest.fm, on Twitter at https://twitter.com/dragonquestfm, and YouTube at https://youtube.com/@dqfm. If you'd like to be exceptionally awesome, our Patreon is http://patreon.com/dragonquestfmThis podcast is not associated with nor endorsed by Square Enix. Music and Sound effects copyright Square Enix.

It took us a while but we finally beat DQ8. This game has memorable characters, monsters with charm, fun mini games, and a skill tree leveling system and fun combat. It definetly stands among the best jrpgs. DISCORD LINK BELOW!!! https://discord.gg/KUbsS448

Jump to the FULL Episode Show Notes here:https://innatopiler.com/podcasts/5-pivotal-hashimotos-hacks-the-empowered-approach-to-thyroid-health/As soon as you find out that you have a thyroid issue, or that you're diagnosed with Hashimoto's, your instinct is to learn as much as you can. As the internet becomes more and more crowded with information, it can be so difficult to find useful information. And, it can be hard to determine who to trust as you try to navigate your way to overcoming your Hashimoto's and hyperthyroid symptoms. I know because I was once in this position and because I've spent the last decade helping Hashimoto's and hypothyroid patients regain their health. A lot has changed in this time - and more changes are coming (more on that at the end of these show notes) but over the years, I've discovered that there are 5 key drivers of success when it comes to overcoming your thyroid issues and Hashimoto's symptoms. I share them in this episode along with a big announcement about this show and support for anyone dealing with autoimmunity, Hashimoto's, and hypothyroidism. The 5 Keys to Overcoming Hashimoto'sThese five proven strategies have made a huge difference for me and many of my clients struggling with Hashimoto's.1. Diet: Balancing Blood Sugar Is Key It all starts with food! While everyone's needs are unique, there's one common thread: balanced blood sugar. Eating a balanced diet with all the macronutrients – carbs, proteins, and fats – is crucial. Avoid blood sugar spikes by avoiding excessive carbs at once and pair your meals with protein and healthy fats. Remember, stress can be physical too! Unbalanced blood sugar creates stress on the body, hindering progress.2. Clean Eating: Ditching Chemicals and Going OrganicOur world is full of chemicals like pesticides and herbicides. Research shows these chemicals can negatively impact our health. So, the cleaner you eat, the better. Prioritize whole, unprocessed foods straight from the earth. Consider going organic, especially for the "Dirty Dozen" – the foods most heavily laden with pesticide residues (check the Environmental Working Group's list). Organic meats and dairy are also beneficial to avoid added hormones and antibiotics.3. Identify and Address Food Sensitivities Gluten is a common culprit for many with Hashimoto's. Not everyone needs to be gluten-free, but some may have the DQ2 and DQ8 genes, making gluten processing difficult. When you consume gluten, even without immediate symptoms, the immune system attacks it. This can lead to accidental attacks on the thyroid due to molecular similarities between gluten and thyroid molecules (cross-reactivity).I personally struggled with gluten for years, but identifying it as a trigger made a significant difference. Consider exploring food sensitivities to see what might be hindering your progress.4. Targeted Supplements for Personalized Support Supplements can be extremely helpful, but a one-size-fits-all approach doesn't work. Our immune triggers and thyroid types vary. However, some supplements have been particularly beneficial for me and my clients:SPM (Specialized Proresolving Mediators): Helps reduce inflammation and calm the immune system.Glutathione: An amazing antioxidant that supports detoxification and promotes immune balance. I recommend the APEX Trizoma Glutathione brand for its liquid form and good taste.Vitamin D: Another immune balancer and natural anti-inflammatory. I recommend Designs for Health's Vitamin D Synergy or Vitamin D Supreme.Remember: These are just a few suggestions. It's important to find what works best for you.5. Calm the Nervous System The nervous system has a powerful influence on the immune system. A calmer nervous system translates to a more balanced immune system. Here are some ways to achieve this:MeditationMovementVisualizationReframing negative thoughtsReleasing negativitySetting positive intentionsAffirmationsFaithMantrasSelf-worth exercises (like clearing feelings of "not enoughness")I find meditation and movement particularly helpful. Experiment and find what works for you.Bonus Tip #1: Building a Morning Practice Can Make a Big DifferenceMornings can be tough, but incorporating a self-care routine can shift the entire day. I recommend starting your day a little earlier, even before the kids wake up (believe me, I get it, I'm not a morning person either!).The book "The Miracle Morning" by Hal Elrod offers great tips on establishing a morning practice and provides ideas to optimize your early-start time. It's hard to believe but the benefits of improved sleep quality and stress reduction outweigh the initial sacrifice of a little extra sleep.Bonus Tip #2: Increase Your Capacity to ReceiveThis may sound surprising, but it's incredibly powerful. We all want optimal health, vibrant energy, and freedom from Hashimoto's. But sometimes, we struggle to allow ourselves to truly receive these things. My question for you is, can you allow all of the things you picture when you see yourself in optimal health? Take a moment and really feel this question in your body. How much good health can you really receive without feeling like, ‘Oh, gosh, this is too much'? All the things that you want to be able to do when you are feeling better; when you have more energy; when you lose that weight – how much of that joy can you actually allow and take in? This might feel like a strange concept, but explore it. Notice any tightness or resistance in your body when you imagine complete freedom from symptoms. Do you feel undeserving of such good health?We often have subconscious beliefs about deservingness. We may feel good things like joy, love, and health need to be earned. This can block our ability to receive the very things we desire.You've heard the stories about lottery winners who lose their winnings quickly. This is often due to a deep-seated feeling of not deserving it. They sabotage their own success.The same can happen with health. If you don't feel deserving of good health, your nervous system won't feel safe receiving it. This can lead to unconscious sabotage of your healing journey.Learning to receive is crucial for overcoming Hashimoto's and any chronic health issues. I have entire programs dedicated to overcoming these blocks: "Clear Your Thyroid Blocks" and my signature program "Thyroid Mystery Solved." You can find more information on my website … which brings me to my important announcement!New Podcast Name and New Website - More Focus on YOUR NeedsIn this episode, I share some exciting updates - including a new name for the show. As you may have noticed from the new podcast cover, the show has transformed!&nb...

This week, it's a special episode of DQFM where Austin recounts his friend Wade, the guy who got him into RPGs back in the '90s and who sadly passed away. From FF7 to DQ8 and Xenosaga, there's a bunch of games mentioned in this episode that will be sure to get your nostalgia bones tingling. You can support this podcast at Patreon.com/DragonQuestFM --- Send in a voice message: https://podcasters.spotify.com/pod/show/dragonquest/message Support this podcast: https://podcasters.spotify.com/pod/show/dragonquest/support

The Investigation It's common for people with Hashimoto's to feel like their thyroid is to blame for their issues. But, it's not the thyroid - it's the immune system. The immune system is attacking the thyroid and causing it to function less than optimally. It's the same with other autoimmune diseases - the immune system is what is malfunctioning.  So, if you have an autoimmune disease and you want to feel better and healthier then you need to support your immune system in a very specific way so that it will stop or slow attacks on your thyroid or any other organ.  As well as supporting the thyroid or other organ involved. In this episode of Health Mysteries Solved, I share more details on this two-fold approach for supporting the thyroid and the immune system. It's definitely for you if you have Hashimoto's but please note that these tips are useful for anyone dealing with autoimmunity.   I also offer a more in depth training on this twofold message. Please be sure you are following me on Instagram so you are the first to know about the next upcoming training. Four Ways to Support the Immune System if you have Autoimmunity Let's start by supporting the immune system. There are many things you can do but in this episode, I share four strategies that have the most impact in supporting your immune system when you have autoimmunity or Hashimoto's. Before we talk about supplements that are generally supportive for Hashimoto's, it's important to note that knowing your own biochemical balances can provide further insights and a more customized approach to supporting your immune system and decreasing your Hashimoto's symptoms.   Immune Calming Supplements There are a few supplements that tend to work well for most people with Hashimoto's and autoimmunity because they have a balancing and calming effect on the immune system. A calmer immune system is less likely to attack! Here are the three best immune calming supplements:   SPM Supreme by Designs for Health. SPM stands for specialized pro resolving mediator. I typically recommend six per day for the first week to quickly down-regulate inflammation. After that, continue with 2-3 per day for maintenance. My listeners save 10% when using this link and entering code DFH10 at checkout.  Trizomal Glutathione. I recommend one teaspoon of this liquid supplement per day. You will need to create an account and login to order this supplement or you can choose the over the counter option of Therasomal Glutathione by Quicksilver. This is a pump liquid and I recommend four to six pumps as a single daily dosage and I find it works best not taken with food. Vitamin D. I especially like Vitamin D Supreme by Designs for Health because it includes vitamin K which is important to take with vitamin D. Remember to use the listener code DFH at checkout to save 10%. Please note that vitamin D should be monitored to determine your dosage because it can fluctuate depending on how much sunshine you are getting and your diet. The lab range is from 31 to 100 (which is very wide). I like to stay between 50 and 70. If your levels are low, you'll want to supplement up to 5000 IU per day but if you are in range, your supplementation can be around 2000 IU daily. It's worth maintaining a good level because I've seen Vitamin D in particular make a huge difference in thyroid antibodies.     These three supplements are the power trio in calming your immune system so it can address the inflammation and viruses it should be attacking instead of your thyroid or other organs.    Immune Calming Mindset Your thoughts, beliefs, past traumas, and the way you support your nervous system play a huge role in your immune system's health. The nervous system is directly tied to your immune system so it makes sense that when our nervous system is challenged, our immune system suffers.   So, what can you do to support your nervous system (and therefore your immune system)? The good news is that little things make a difference. Here are a few small shifts you can make in your daily life that can add up to big changes in your mindset and the state of your nervous system. Start your day with two minutes of intentional breathing  End your day with two minutes of gratitude before you go to bed Thank your body for holding you up all day Believe in the infinite wisdom that your body has this amazing gift that it can heal and give it a chance.  Shift your thoughts and language to the possible, for example instead of saying ‘I have to' try saying ‘I want to', ‘I get to', ‘I choose to.'  The most important thing to remember is that our bodies are not net neutral, they're net positive. Anything you can do to help calm and down-regulate your nervous system will have a huge effect on your immune system.    Immune Calming Diet A lot of people living with Hashimoto's or autoimmunity ask me about what diet to follow because they hear so much about going gluten-free, grain-free, dairy-free or following the AIP (Autoimmune Protocol) diet. There are a lot of choices out there and each person is going to have their unique food intolerances and sensitivities. In my experience, working with thousands of people at this point, I find that gluten and dairy tend to really be the big things that move the needle. Now again, for some people they may need to do grain free or they may need to do low lectin or AIP. And when you start out, sometimes doing a little bit more is helpful and then you can narrow down exactly what can be added back in safely. Some people find that eliminating too much is too much so for them, I do suggest eliminating gluten and dairy to see significant changes.  Food tests can be very helpful to identify specific individual issues. On the genetic front, you can also test the DQ2 and DQ8 will identify if you struggle to process gluten. My other go-to test is the Vibrant America Zoomer test that will identify sensitivities with dairy as well as foods like soy, eggs, nuts, and even other grains. It's very comprehensive because they look at different immunoglobulins (IgG and IGA) and they also break out the gluten and the dairy into a lot of metabolites of those foods. This is a test that I use in my practice all the time. If you are interested in doing this test, please contact us. Getting more information about your body and how it functions will allow you to make the right choices with your diet so that your immune system isn't triggered by your food.    Immune Calming Physical Activity Losing weight is usually one of the big goals with almost all of my clients and the students in my Thyroid Mystery Solved Program. And, I understand that because Hashimoto's and hypothyroidism often leads to unwanted weight gain and can make it harder to lose weight.  The go to solution is often to exercise more but workouts that are too intense can actually make things worse and upregulate the immune system even more. This is because overtraining feels like stress to the body and that elevates your cortisol which can make you hold on to pounds instead of dropping them.  The other side effect of excessive workouts is that they leave you feeling tired which can put a strain on your immune system.  The key to immune calming physical exercise is to do it but not overdo it. Exercise is good but if it leaves you feeling stressed or tired the next day, it's too much.  Next Steps After listening to my episode, I hope you are seeing that small, simple shifts are all it takes to support the immune system and reduce the symptoms of your autoimmune disease like Hashimoto's.  You can start making these changes right away or you can work with your doctor. I know that doing the research can be overwhelming and time-consuming which is why I created my personalized  Thyroid Mystery Solved Program. It's a one-of-a kind, online self-study program where you get a plan that is actually customized to you and your thyroid type. We identify your type and based on that, we work on the diet, the lifestyle, the nutrients, and the organ support that's specifically for you. Plus, you have access to me.  It's a much more cost-effective way to work with me compared to my one-on-one consulting VIP program. However if you are interested in one on one, I do have this option as well and you can see much more information by clicking here. My goal is to support you however you need that support.    Eliminating Health Mysteries When it comes to reducing the symptoms of Hashimoto's and other autoimmune diseases, we have to support the immune system. Now you have 4 strategies to calm the immune system. Could this be the missing clue for you or someone in your life?  Links: Resources mentioned: Thyroid Mystery Solved Program 6-month, VIP Private Consulting   Suggested Products SPM Supreme by Designs for Health Glutathione Trizomal Glutathione → create an account and login to order  Therasomal Glutathione by Quicksilver Vitamin D Supreme by Designs for Health Remember, Health Mysteries Solved listeners save 10% on Designs for Health products when they use their special code: DFH10   Related Podcast Episodes: The Super Simple Mindset Shift to Help Hashimoto's Top 5 Things I Wish I'd Done Sooner on my Hashimoto's Healing Journey The Biggest Hidden Food Trigger for Hashimoto's and Autoimmune Diseases You Need to Know Top 5 Mistakes When Navigating the Many Symptoms of Hashimoto's The Case of the Stubborn Hashimoto's w/ Dr. Kyrin Dunston The Case of the False Negative Celiac Test w/ Dr. Peter Osborne Thanks for Listening If you like what you heard, please rate and review this podcast. Every piece of feedback not only helps me create better shows, it helps more people find this important information. Never miss an episode -  Subscribe NOW to Health Mysteries Solved with host, Inna Topiler on Apple Podcasts, Spotify, Stitcher or Google Podcasts and remember to rate and review the show! Find out more at http://healthmysteriessolved.com   PLEASE NOTE All information, content, and material on this podcast is for informational purposes only and is not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified physician or healthcare provider. Some of the links provided are affiliate links. This means we may make a very small amount of money should you choose to buy after clicking on them. This will in no way affect the price of the product but it helps us a tiny bit in covering our expenses.

This week, we're trying to answer the age-old question - "Why has Dragon Quest struggled in the West?" And we think we found an answer! This should've been a Questy Boys episode! Oh well, hindsight is 20-20 and all that. Anyway, we talk a lot about the history of Dragon Warrior in the NES days as well as DQ8's launch and why Dragon Quest XI came at JUST the right time. You can support this podcast by visiting Patreon.com/DragonQuest --- Send in a voice message: https://anchor.fm/dragonquest/message Support this podcast: https://anchor.fm/dragonquest/support

There has been a steady rise in autoimmune disease throughout industrialised societies over the last 30 years. Almost 4.5% of the world's population is affected by one of more than 80 different autoimmune diseases.To add to these already alarming statistics, recent studies have revealed that the incidence of autoimmune diseases worldwide is increasing at a rate of 19% per year.While we know that numerous predisposing genetic risk factors have been identified, these only account for a fraction of the overall incidence of autoimmune diseases.There are studies pointing to a strong influence of environmental and lifestyle factors, but translating this into a meaningful therapeutic model is a challenge, especially under the current, prevailing medical paradigm.Nevertheless, there are those who have pioneered this field of research and, through their personal and professional endeavours, have made it all but impossible to ignore how profound an impact diet, lifestyle and mindset can have when faced with seemingly intractable conditions.Dr Terry Wahls is a clinical professor of medicine at the University of Iowa. In 2000, she was diagnosed with relapsing remitting multiple sclerosis and from that point, began to steadily decline. Because of her academic medical training, Terry began a research journey that eventually led her to investigate these under-explored factors and from this she developed a treatment plan that would help restore her health. Today, Dr Terry Wahls is a teacher and mentor to millions of people around the world who are seeking more effective ways to treat multiple sclerosis and other progressive health problems.Her story is truly inspirational and we are so fortunate to have Terry share this on the IMH Patient Journeys podcast. References:Jamka M, et.al. The Effect of the Paleolithic Diet vs. Healthy Diets on Glucose and Insulin Homeostasis. J Clin Med. 2020;9(2):296. Challa HJ, Bandlamudi M, Uppaluri KR. Paleolithic Diet. [Updated 2022 May 2]. Abbott RD, et.al. Efficacy of the Autoimmune Protocol Diet as Part of a Multi-disciplinary, Supported Lifestyle Intervention for Hashimoto's Thyroiditis. Cureus. 2019;11(4)Gauree G. et.al. Efficacy of the Autoimmune Protocol Diet for Inflammatory Bowel Disease, Inflammatory Bowel Diseases, Volume 23, Issue 11, 1 November 2017, Pages 2054–2060Cecilio LA, et.al. The prevalence of HLA DQ2 and DQ8 in patients with celiac disease, in family and in general population. Arq Bras Cir Dig. 2015 Jul-Sep;28(3):183-5.Mangalam, Ashutosh et.al. (2009). HLA-DQ8 (DQB1*0302)-restricted Th17 cells exacerbate experimental autoimmune encephalomyelitis in HLA-DR3-transgenic mice. Journal of immunology.Santoro L, et.al. Looking for celiac disease in Italian women with endometriosis: a case control study. Biomed Res Int. 2014;2014 Małgorzata Królik, et.al. Possible effect of the HLA-DQ2/DQ8 polymorphism on autoimmune parameters and lymphocyte subpopulation in recurrent pregnancy losses, Journal of Reproductive Immunology, Volume 149, 2022,Garcia J, et.al. Social isolation and connectedness as determinants of well-being: Global evidence mapping focused on LGBTQ youth. Glob Public Health. 2020 Apr;15(4):497-519. doi: 10.1080/17441692.2019.1682028. Epub 2019 Oct 28. Rothman, Emily F.et.al. "The Prevalence of Sexual Assault Against People Who Identify as Gay, Lesbian, or Bisexual in the United States: A Systematic Review". Trauma, Violence, & Abuse. 12 (2): 55–66. Brenton JN, et al. Phase II study of ketogenic diets in relapsing multiple sclerosis: safety, tolerability and potential clinical benefits. J Neurol Neurosurg Psychiatry. 2022;93(6):637-644.

It's Valentine's Day week, so this time around, we're discussing romance in the Dragon Quest series. From marriage options in XI S to choosing a bride in DQ5 and romancing a horse in DQ8, we (try) to cover it all. Plus, puff-puff! If you'd like to support this podcast, please visit Patreon.com/DragonQuestFM. Shoutout to all our new and current patrons! We love you! --- Send in a voice message: https://anchor.fm/dragonquest/message Support this podcast: https://anchor.fm/dragonquest/support

The Wide Range of Hashimoto Symptoms Hashimoto's is complex and often misunderstood by mainstream medicine. It's a topic that I have a lot of experience with both personally and professionally and know that so many of you are struggling with its many symptoms. Because of this,  I knew that dedicating the 100th episode of this podcast to the topic was exactly how I wanted to celebrate this milestone.  One of the most common questions I get about Hashimoto's is whether a specific symptom is related to Hashimoto's. Hashimoto's has a wide variety of symptoms and it can be difficult to figure out if something is related to Hashimoto's or if it is a symptom of something else. It's very frustrating.  People ask me about  fatigue, anxiety, GI issues, hair loss, fertility challenges, brain fog, rashes, and even eye twitches. How can all of these be symptoms of Hashimoto's (especially when not everyone with Hashimoto's has these symptoms?  It's important to remember that Hashimoto's is not a thyroid disease but an autoimmune disease that affects the thyroid. And remember, the thyroid may not be the only organ affected by Hashimoto's. This is why there can be such a wide range of symptoms.    The Problem with the Conventional Approach to Hashimoto's The relationship of these various symptoms to Hashimoto's is often missed in conventional medicine. As a result the symptoms aren't supported. Many doctors will focus solely on how the thyroid is affected and simply support thyroid function instead of supporting immune system function. If the thyroid is functioning well, many doctors will tell their patients that there is nothing else they can do about their Hashimoto's and rather just wait until it destroys the thyroid at which point they will then need medicine.  The more integrative approach is to dig into how the immune system got confused in the first place and address each one of those things to help the immune system rebalance while supporting the thyroid.    The Biggest Mistakes with Supporting Hashimoto's Symptoms In this episode, I tackle the biggest mistakes that people with Hashimoto's can make. This is so that you can be aware of the relationship between the many symptoms and your Hashimoto's and so you can be a better advocate for your own health.    Hashimoto's Mistake #1 - Only Focusing on Thyroid while Ignoring the Immune System Many people with Hashimoto's are given thyroid medicine. When thyroid levels are back to normal, the issue is considered in hand without a second thought as to why the immune system got confused and started attacking the thyroid in the first place. This is one of the most common mistakes.  In episode 32 (Solving the Autoimmune Mystery), I go into detail about the connection between the immune system, Hashimoto's and other autoimmune diseases.  In a functional approach, our goal is to figure out the root cause of the issue. With autoimmunity we look at immune triggers. These can be grouped into four categories: Foods Stress Toxins Infections Understanding these triggers can have a profound effect on how your body deals with your symptoms.    Hashimoto's Mistake # 2 - Supporting the Immune System, Not the Thyroid While I just explained the importance of triggers, some people with Hashimoto's will work on reducing triggers with the hope that it will fix their thyroid. If the thyroid is already in a hypo state, it may require medication to bring it to a healthy level. Remember, the thyroid interacts with all cells in the body and many organs. When it is not functioning properly, it can have a profound effect on your overall well being. I understand the hesitation to take medication. I will always try to find a natural solution to any issue, but, when it comes to the thyroid, there is a real danger of harm to our body if it is not functioning.  Your thyroid plays a key role in: Metabolism Blood Sugar Weight Management Body Temperature Mitochondria Muscle Tone Bone Density Membrain Health (specifically in your brain and gut) Inflammation Management Creation of Antioxidants (that control free radicals) Brain Function Immune System Health You can see how many of these things are connected and how a wide variety of symptoms and new health issues can crop up when your thyroid is not properly supported. It's critical that you make sure your thyroid is getting enough support. For more on this, please check out this free guide: Why Is Your Doctor Missing Your Thyroid Issue? which explains how the thyroid really works and how to interpret your thyroid markers.   Hashimoto's Mistake #3 - Not Personalizing your Thyroid Support Supporting the thyroid is not a one size fits all approach. Just because something works for someone else, does not mean it will work for you because there are different types of slow thyroid types.  If you've listened to the show before, you know that I talk a lot about getting the full thyroid panel instead of just testing your TSH levels. This is because your different levels help to identify what type of thyroid issue you have.  For example, you may have enough T4 but it may not be converting to T3. If you are on medication (like Synthroid), it is providing you with T4 but that won't help you if you are not converting to T3.  Plus, with an autoimmune disease like Hashimoto's the immune system could be attacking the thyroid where conversion happens.  The main point here is that your thyroid treatment needs to be personalized to you based on what the data from your lab reports reveal.  Triggers also vary from person to person and should be considered in the treatment plan. Some are general with Hashimoto's, like exposure to chemicals and BPA plastics. Another example of a trigger is gluten which is commonly a trigger for people with Hashimoto's (many have the celiac genotypes DQ2 or DQ8 which you can learn about in Episode 9). Infections, leaky gut, or Epstein Barr Virus can also be triggers that should be considered in a treatment plan.  You want to know what's going on and look at the big picture before determining your personalized plan.    Hashimoto's Mistake #4 - Doing Nothing Because Thyroid Function is Fine This mistake happens all the time because it's exactly what many conventional doctors advise patients to do. Their theory is to wait until the Hashimoto's starts to destroy the thyroid before taking any action.  I don't know if you know this but thyroid destruction can be going on for months, even years before thyroid levels may show it.  Hashimoto's patients may also experience inflammation (in the thyroid or other parts of the body) which can bring on other symptoms even though thyroid levels are fine.  If you know you have Hashimoto's, don't wait for your thyroid to get destroyed, start balancing your immune system right away. This can include working on your diet, checking for gluten or other food sensitivities, reducing your exposure to chemicals in your home and office, keeping stress in check, and paying attention to triggers and symptoms.  Even if you are not working with a functional medicine practitioner, you are not, you can still do a ton on your own to balance and support your immune system.    Hashimoto's Mistake #5 - Not Testing Thyroid Frequently Enough We know that Hashimoto's causes the immune system to attack the thyroid but the strength and frequency of the attack is going to vary from person to person. For some, it might be a mild attack that can be managed by balancing the immune system. For others, the attack might be significantly more severe with destruction of the thyroid happening quickly.  Immune triggers like stress, toxin exposure, or big hormone changes can cause a Hashimoto's flare up. This can result in a swift and severe attack that leads to significant thyroid inflammation. Attacks like this can cause the thyroid to suddenly release stored hormones into the bloodstream. Episodes like this can create dips and spikes as well as an overburdened thyroid as it struggles to correct itself. This comes with it's own set of symptoms.  It's important to test frequently enough to see where you are and support your thyroid as needed. Some people only test tsh and other thyroid labs once a year or even less frequently and they may be missing the flare ups and times where more support is needed. I personally test my thyroid every 3 months. However, if you are someone that has unrelenting symptoms and have noticed that your TSH has fluctuated in the past, testing every quarter or even more often, is going to be very helpful.    Coming Soon - Your Personalized Approach to Solving your Thyroid Mystery I've talked about this in the past and it's been something I've been working on for the past 2 years. And now, I am about to make it available and I can't wait.  Coming later this Fall, I will be releasing an online course that will show you the step by step process of balancing your thyroid and Hashimoto's specifically for you. This course has been a labor of love and the reason it has taken me so long to create is because I recognized how vital it was for it to be customized and this added a lot more material to cover as many possible situations as I could.  But now, it's almost ready. Stay tuned for more on that in the months to come.    Links: Resources mentioned Why Is Your Doctor Missing Your Thyroid Issue? FREE GUIDE   Related Podcast Episodes: Solving the Autoimmune Mystery The Case of the False Negative Celiac Test w/ Dr. Peter Osborne Everything You Need to Know to Interpret Epstein Barr (EBV) Results Thanks for Listening If you like what you heard, please rate and review this podcast. Every piece of feedback not only helps me create better shows, it helps more people find this important information. Never miss an episode -  Subscribe NOW to Health Mysteries Solved with host, Inna Topiler on Apple Podcasts, Spotify, Stitcher or Google Podcasts and remember to rate and review the show! Find out more at http://healthmysteriessolved.com   PLEASE NOTE All information, content, and material on this podcast is for informational purposes only and is not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified physician or healthcare provider. Some of the links provided are affiliate links. This means we may make a very small amount of money should you choose to buy after clicking on them. This will in no way affect the price of the product but it helps us a tiny bit in covering our expenses. 

It's episode four of our deep dive into Dragon Quest VIII! This week, Austin's mic was being weird (so sorry about that), but we sat down to talk about the most memorable bosses and baddies in DQ8. Plus, at the end, we had a nice little pop quiz to see if B.J. remembers any of it. You can support us by visiting Patreon.com/DragonQuestFM You can also find us on Twitter @DragonQuestFM --- Send in a voice message: https://anchor.fm/dragonquest/message Support this podcast: https://anchor.fm/dragonquest/support

This week, real life happened, so we weren't able to meet up and record together. However, we did record this Rocket Slime episode a couple of weeks ago. It actually ties into our Dragon Quest VIII deep dive episodes in a big way, since there are so many references to DQ8 found in Rocket Slime. So if you've never listened to this episode, or if you want a refresher, you can check it out this week! We'll be back next week to continue our deep dive into Dragon Quest VIII! --- Send in a voice message: https://anchor.fm/dragonquest/message Support this podcast: https://anchor.fm/dragonquest/support

This week on DQFM, we're continuing our discussion of characters and placed in Dragon Quest VIII. We talk about plot points like King Pavan in Ascantha, Prince Charmles and hunting for Argon Hearts, and breaking up a wedding like it's the end of a romantic comedy! Plus, we read some of YOUR thoughts on favorite DQ8 moments. You can support this podcast by visiting Patreon.com/DragonQuestFM You can also find us on Twitter @DragonQuestFM --- Send in a voice message: https://anchor.fm/dragonquest/message Support this podcast: https://anchor.fm/dragonquest/support

The Investigation In a previous episode, I revealed what I eat on a regular basis to stay healthy and I was thrilled to get so much positive feedback about it. So, I thought I would pull the curtain back a little further and share what I feed my kids to keep them healthy now and to help them develop a good relationship with nutritious food. In this episode, I walk you through what my 5 year-old son and 9-month old baby daughter eat now and what they ate getting to this age. I know that kids are not easy when it comes to food. I hear, ‘my child is a picky eater!' all the time and mine are too. It can be tough, but remember, that even if they don't like something, it does not mean they won't like it forever. In fact, studies show that kids have to try a food over and over again before they learn to like it so don't give up after one or even a few tries.    Introducing Healthy Foods Early You can expand a child's palate and willingness to try new things by introducing healthy foods and supplements at an early age. For example, I started giving Jake, my 5-year-old, liquid fish oil (Omega Marine Liquid) at such a young age, that he is totally used to the taste. He will even remind me when I've forgotten to give it to him.  And the baby gets excited now whenever I pull that fish oil bottle out of the fridge.  I also introduced Jake to probiotics at an early age by opening up the capsule and sprinkling it into his food. Sometimes you have to get creative!  It's worth it because the more you introduce to them early on, the more they will get used to these foods and it will be easier later.     When to Start Babies on Solid Food There's always been debate over exactly when babies should start eating solid foods. These days, pediatricians recommend introducing solid food between 4 and 6 months (it used to be 6 months). The thinking is that introducing solid food earlier (including potential allergens) may decrease the chances of the child developing food allergies to things like peanuts, dairy, egg etc. I think there are a few sides to this story though.  First, some kids are just not ready for solids so pushing those too early may be stressful for both you and the child. Second, while I understand introducing small amounts of allergens early is sort of like doing allergy shots, you have to remember that babies are born with essentially a leaky gut. It takes time for that to fill in. In my opinion, it's better to wait especially if there's a family history of autoimmune disease.  In my case, I have Hashimoto's and I have the DQ8 gene for gluten so I knew that my kids would be at risk of also having this gene. In fact, I had my kids tested to determine if they inherited this gene (there's no such thing as too early for genetics) and I discovered that they actually had both the DQ2 and DQ8. As a result, I have never given them gluten.  For dairy, I waited until Jake was a year old. If you have a dairy intolerance, be sure to listen to the full episode because I explain how introducing dairy too early could result in cross-reactivity or molecular mimicry with dairy and the islet cells on the pancreas which can lead to an autoimmune reaction for type 1 diabetes. Of course there are many other factors involved but I just personally felt that dairy was not necessary for us and waited till a year after which this may be less likely to happen.   How to Start Babies on Solid Food If you were to follow the conventional recommendations for slowly adding in solid foods, pediatricians suggest putting rice cereal in the breast milk or formula. After that, introducing rice or oats and soft foods like bananas and other fruits.  My recommendations are a bit different.  If they are getting enough calories from breast milk or formula, there is really no need for grains or fruit so early on. Instead of helping them develop a taste for sweet food, encourage them to experience veggies instead. With both Jake and Juliette (the baby), I started with zucchini that I steamed and pureed. I added a bit of breast milk but you could also just add a little water too.    Pureeing Your Own Veggies for Babies I know there are a lot of healthier options for buying pureed baby food but I prefer to make my own because, as I said, I want to avoid the sweeter fruits and veggies early on so I can help the kids develop a palate for things other than sweet.  I started with zucchini (which I peel to avoid too many lectins), avocado, green beans, bok choy, and cauliflower. As the babies got a little older, I added in kale, broccoli, butternut squash, and swiss chard. Next, I started to integrate sweet potato and beans. The next addition was pureed meat, egg, and nuts. All of this was before I introduced fruit around the 8-9 month mark.    Are Puffs Really Good for Babies? Anyone who's had a baby in the last few years knows what puffs are - they're everywhere. The idea is that they help babies develop because they have to pinch them to pick them up s its good for their fine motor skills and they dissolve in the mouth so they're not hard to eat.  I suggest really looking at the ingredients before jumping on this trend. I did find one brand of puffs, Lesser Evil Puffs, that seemed to be not too bad. I prefer to make bite-sized soft foods myself. This might be pressure cooked chicken or lamb, or veggie puree rolled into balls and baked. The baby can still grab it and I know that healthy, whole foods have been used to make them.    Helping Picky Eaters Love Vegetables I know a lot of parents deal with kids who are picky eaters. Often, when we find one healthy food they like, we continue to give it to them until they get bored with it. That doesn't mean they don't like it anymore, it just means it's time for a break. I try to rotate his foods and always have a balanced plate (grains, veggies, and protein) just like I do for us adults.   Another thing you can do is pay attention to what your picky eater does like - it might not be the food they're rejecting but how it's prepared so you can look for patterns. Do they like soft foods, crunchy foods, certain colors or flavors? If so, work with that. I noticed that Jake really likes crunchy foods so I try to make our healthy food crunchy so he'll eat it. For example, I'll bake asparagus tips or zucchini fries in the air fryer.    Meal Plan for a Child Here is a typical day of eating in our house.  Breakfast: Birch Bender Paleo Waffles with cashew butter OR 2 oat and banana muffins with either cashew or almond butter. Sometimes eggs and gluten-free toast or Grain-free Buns from Coco Bakes. Lunch: A protein (grilled chicken, steak, pork chops, lamb), a side (oats, rice, sweet potato, beans) and veggies (asparagus tips, steamed green beans, air fried eggplant, zucchini, broccoli). Dinner: Similar to lunch and we will often rotate these around. If we include a dessert, it's usually frozen berries, NadaMoo! dairy-free ice cream or chocolate (HU Chocolate is low in sugar). Sometimes I'll make muffins or brownies using the SimpleMills mixes. School Lunch: Meat sandwich (turkey or meatballs), side of veggies, and sometimes a protein drink (we like the Paleo Pro Chocolate).  Snack: Jakes likes the Egg White Curls from Lesser Evil as well as SimpleMills' crackers, cauliflower chips, and nut butter. And, of course, fruit.    Healthy, Gluten-Free Brands our Kids Love Birch Bender Paleo Waffles Grain-free Buns from Coco Bakes. Soozy's makes good grain-free bagels Simple Kneads for bread. SimpleMills for snacks and I use their muffin and brownie mix   Supplements for Kids There are a few supplements that most kids can really benefit from: Fish oil  - If you have a picky child, you might try adding OmegAvail Smoothie (by Designs for Health) to their smoothie. There are great flavors like Mango Peach.   Probiotics (starting at 6 months) Bone broth stating around 6-7 months (great for extra hydration) Multivitamin - We like SuperNutes but SmartyPants is also good.  Vitamin C - Kids find C+biofizz fun and tasty Vitamin D (especially if you don't live in a sunny climate) - Emulsi D3 Synergy  Allimax is good to have on hand for when kids feel a little under the weather or there's something going around.    Starting Kids Strong I know nutrition for kids can be a real challenge. I've been successful (or lucky) that introducing healthy foods at an early age has helped my kids maintain a balanced diet. Could my tips help a mom or a mom-to-be feel more confident in their feeding habits? Please share this episode.   Resources mentioned:   Zucchini Fries Recipe INGREDIENTS 1 Tablespoon Avocado Oil ¾ teaspoon salt 1 teaspoon Italian seasoning 1 ½ Tablespoons Gluten Free All purpose flour ¾ cup gluten free breadcrumbs (I use Sogni Dolci brand) 2 medium zucchini, cut in quarters lengthwise and then each quarter halved 2 large egg whites, whipped until frothy (almost soft peaks) DIRECTIONS Preheat oven to 500ºF. In a small bowl, mix together Italian seasoning, flour and salt. Place bread crumbs in another small bowl. Dredge a zucchini fry in flour mixture and then dip into egg whites; dredge in bread crumbs. Place coated zucchini on parchment paper on baking sheet and repeat with remaining ingredients. Roast, turning once, until desired crispness, about 10 minutes. Use this technique with any summer squash or even eggplant. Works great with thick-cut onion rings or even green tomatoes. Related Podcast Episodes: Want to Know What a Nutritionist Eats? Plus Ideas for You The Case of the Toddler Who Won't Sleep w/ Kimberly Walker Thanks for Listening If you like what you heard, please rate and review this podcast. Every piece of feedback not only helps me create better shows, it helps more people find this important information. Never miss an episode -  Subscribe NOW to Health Mysteries Solved with host, Inna Topiler on Apple Podcasts, Spotify, Stitcher or Google Podcasts and remember to rate and review the show! Find out more at http://healthmysteriessolved.com   PLEASE NOTE All information, content, and material on this podcast is for informational purposes only and is not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified physician or healthcare provider. Some of the links provided are affiliate links. This means we may make a very small amount of money should you choose to buy after clicking on them. This will in no way affect the price of the product but it helps us a tiny bit in covering our expenses. 

The Case:  Linda was having trouble with anxiety and sleep Routine blood work revealed a very high TSH (thyroid stimulating hormone) and she was given a medication to treat hypothyroidism. Linda wondered why she didn’t have many of the typical symptoms for hypothyroidism and worried that going on medication might be the wrong move.   Even though Linda was happy to have an answer, something didn’t add up. She was told to get on the medication, regardless of whether she showed typical symptoms or not. Linda wasn’t convinced. That’s when she came to see me.    The Investigation Linda was right to question her results and her treatment even though her numbers were very high. I knew I needed to figure out the root cause of her elevated TSH and determine if there might be a way to get her back into optimal range.    Normal Range for Thyroid Stimulating Hormone (TSH)  The regular lab range for TSH is between .5 and 4.5, but the more functional range that we want to aim for is really between 1.8 and 3 if not medicated. Linda’s TSH was at 19, which was why her doctor was immediately alarmed.    Evaluating Thyroid Markers or Why You Need To Test All Thyroid Markers In order to truly evaluate the thyroid, it is very important to test all of the thyroid markers (as I explained in Episodes 27 & 28). We ran a second blood test with TSH and all the thyroid hormones as well as all 3 antibodies: TPO, thyroglobulin, and TSI antibodies. When the results came back with high TSH (even higher than before!), the interesting thing was that the other actual thyroid hormone markers were completely normal. Linda’s T3 and T4 were at optimal levels. Typically, when those thyroid hormones drop, the body’s signal to correct that would be raising the TSH. We were able to see here that the other hormones had not dropped in the first place, so that was not the reason the TSH was up.    High TSH with High Thyroid Antibodies  In Linda’s case, she didn’t have typical hypothyroid or slow thyroid symptoms and her thyroid hormones were normal. Her TPO antibodies however were 529, which is quite high. Her thyroglobulin antibodies were also slightly elevated at 42 and her TSI antibodies were negative. TSI antibodies are representatives of Graves disease, so she didn’t have that, but TPO and Thyroglobulin antibodies are representative of Hashimoto’s. Linda’s results were positive for TPO and Thyroglobulin, which showed us that she had Hashimoto’s.    Hashimoto’s and Thyroid Inflammation When there is Hashimoto’s there can also be thyroid inflammation. I have found that when the thyroid is inflamed, the TSH can go up without it triggering any low thyroid hormones. This is not what the textbooks say in typical cases, but as we know here at Health Mysteries Solved, many of us are not textbook cases, and issues can be complex!   Misdiagnosed Hypothyroidism  Our bodies have tons of feedback loops and when all the loops work like they are supposed to, then we can follow a textbook pathway to healing. But, in many cases, there are other issues at play from stress to autoimmunity to toxicity, to the foods that we eat. It’s not uncommon that the feedback loops may not work the way we think they should. In this case, High TSH is showing inflammation of the thyroid rather than an actually slow thyroid. This not only explains why she didn’t have hypothyroidism symptoms, but also that the inflammation could have actually been triggering the anxiety and sleep issues.    Medication when Necessary I was so happy that I met Linda so that we could work on the inflammation. In her case, medication was actually not necessary because her thyroid hormones were normal.  Even though I am always trying to find natural solutions, I am not anti-medication when truly necessary. Especially when it comes to thyroid medication. As some of you may know, I take a small dose of compounded thyroid medication because I have hypothyroidism. My perspective is that when the thyroid truly is slow, medication is replacing something that the body can’t make but absolutely needs. This is a very important medication for me to have. However using it when you don't need it is a different story.   The Link Between Hashimoto’s and Hypothyroidism? While many people with Hashimoto’s do in fact have hypothyroidism (because of damage to the thyroid), other times, we can catch the Hashimoto’s and the inflammation it may cause early before the thyroid gets damaged. In this case, if we address the inflammation and underlying immune triggers driving the autoimmune response, it is possible to save the thyroid from being destroyed.  By the time I found out I had Hashimoto's, my thyroid was already affected but even if that is the case for you, there is still a lot you can do to stop the progression of the attack by addressing the triggers.   Next Steps For Linda, we caught the Hashimoto’s early before it actually damaged her thyroid. We worked on lowering inflammation and calming her adrenal glands (the glands that deal with stress), which was one of her triggers. We did a genetic test for gluten, the D2 DQ8 which showed that she was positive for both the DQ8 and D2 (meaning her body was not genetically predisposed to process gluten). There is a big connection between gluten and Hashimoto’s due to molecular mimicry (where there are similar molecules at play so the body attacks all of them by mistake). We took gluten out of her diet and used PS 150 and liquid GABA to help lower her cortisol and support her adrenals and sleep. Stress can be both physical as well as emotional and so for Linda, we reduced the physical stress caused by her body trying to process gluten. She also added mindfulness exercises to further lower her cortisol. This  helped her calm down, relax and feel less anxious which, along with the GABA, improved her sleep.  The better she slept, the more her adrenals were able to heal. We retested her full thyroid panel of markers in 6 weeks and her TSH had returned to normal! We were both thrilled. Eliminating Health Mysteries Can you see how this could have become quite a health mystery had she not explored this further? I am so glad she did reach out for support, and hope you can keep her story in mind in case you ever get similar results. For Linda, we were able to find that missing piece of the health puzzle so she could regain her health. Could this be the missing clue for you or someone in your life?    Links: Suggested Products Liquid GABA PS 150 Related Podcast Episodes: EPISODE #028 Navigating the Thyroid Treatment Mystery with Inna Topiler EPISODE #027 Solving the Thyroid Mystery w/ Inna Topiler EPISODE #080 The Link Between Dry Eyes and Your Thyroid w/ Dr. Rani EPISODE #078 [Ask Inna] Your Thyroid and Hashimoto’s Questions Answered Thanks for Listening If you like what you heard, please rate and review this podcast. Every piece of feedback not only helps me create better shows, it helps more people find this important information. Never miss an episode -  Subscribe NOW to Health Mysteries Solved with host, Inna Topiler on Apple Podcasts, Spotify, Stitcher or Google Podcasts and remember to rate and review the show! Find out more at http://healthmysteriessolved.com   PLEASE NOTE All information, content, and material on this podcast is for informational purposes only and is not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified physician or healthcare provider. Some of the links provided are affiliate links. This means we may make a very small amount of money should you choose to buy after clicking on them. This will in no way affect the price of the product but it helps us a tiny bit in covering our expenses. 

In this episode of the Help For Leaders Podcast, Stacey talks about the complexities of communication. From Verbal to non-verbal and from body language to Tone, we will go over it all! Watch this episode on Youtube here: https://www.youtube.com/watch?v=_DQ8-b-KemQ Take the free work from home assessment here: https://disc-report.com/products/wfh-assessment

This week, we’re talking about translation and localization in Dragon Quest games. It’s a bit of a touchy subject with some fans. I compared it to putting my hand in a beartrap a while back. It’s like, you can’t please everyone, and no matter, you’re losing a few fingers. So let’s put our hands into that bear trap! It all goes back to early Dragon Quest games. Everyone talked in Ye Olde English. Which we both kinda hate. Turns out, Yuji Horii does too! Here's the link to Polygon article where he says this Since then, it’s been a weird contention with a lot of fans. People either think the translators stray too far from a direct translation - or they prefer certain translators over others. Luckily, Austin got to interview an actual DQ translator. So we talk about Austin’s interview with Nob Ogasawara. Not only did he work on DQ, but he also did most of the Pokemon games that made us love the series. Then Paul Handelman came around and basically united everything under a new Western translation canon. That’s how you got Torneko Taloon’s full name and differences in Gabo/Ruff and such. Why do fans get so mad about translation/localization? I kinda get it. I mean, if I’d played a game for sixteen years and then characters I knew and loved suddenly had new names, I might be a little ticked too. But, honestly, I don’t really care. I’m just like...you know what, it’s clear they’re trying to get more involved with localizations now. Yuji Horii has basically said until DQ8 he wasn’t super involved directly with translation, so it’s kinda a George Lucas/Star Wars scenario. Do you say Greedo shot first, or do you go with the creator’s new vision? https://patreon.com/dragonquestfm --- Send in a voice message: https://anchor.fm/dragonquest/message Support this podcast: https://anchor.fm/dragonquest/support

The Investigation Chances are you know someone with a gluten sensitivity despite reports that only 6-7% of the population suffer from it. That’s because testing is tricky and false negatives can make people think their health issues are caused by something else. In this episode, I want to break down what’s going on and help you determine if a gluten sensitivity might be at the root of your health mystery.    Understanding Gluten Intolerance Gluten is a protein found in wheat, rye, barley and oats. A person with gluten intolerance cannot digest the protein portion of these grains which triggers an immune response to what the body deems a foreign substance. This immune reaction causes inflammation in the digestive system and damages the lining tissue which, in turn, can cause symptoms like fatigue, bloating, diarrhea, constipation, gas, and cramping. The compromised lining can leave the person more susceptible to bacteria, parasites, and funguses.  Overtime, if a person who has a gluten intolerance continues to eat gluten, their small intestine may also become damaged which leads to malabsorption of nutrients. This can cause fatigue and weight gain. And, the person will be at an increased risk of insomnia, osteoporosis, hormone imbalances, inability to deal with stress, and mood swings. Over time, additional issues may arise like lactose intolerance, depression, leaky gut syndrome (leading to higher susceptibility to infections and other illnesses.) Gluten Intolerance is the Root Cause of Many Health Issues Symptoms of Gluten Intolerance There are many symptoms that could be the result of a gluten intolerance. How many from this list can you check off?    Weight gain Unexplained fatigue Difficulty relaxing, feel tense frequently Unexplained digestive problems Female hormone imbalances, (PMS, menopausal symptoms) Muscle or joint pain or stiffness of unknown cause  Migraine like headaches Food allergies/sensitivities Difficulty digesting dairy products Tendency to over consume alcohol Overly sensitive to physical and emotional pain, cry easily Cravings for sweets, bread, carbohydrates Tendency to overeat sweets, bread, carbohydrates Abdominal pain or cramping Abdominal bloating or distention Intestinal gas “Love” specific foods Eat when upset, eat to relax Constipation or diarrhea of no known cause Unexplained skin problems/rashes Difficulty gaining weight Anorexia Bulimia Rosacea Diabetes Osteoporosis/bone loss Iron deficiency/anemia hronic fatigue Candida Hypoglycemia If you checked off 4 or less it is very unlikely that you have a gluten sensitivity. If you scored between 5 and 8 there may be a reason to suspect it. If you scored 9 or higher there can be a good chance that you are gluten sensitive.   What is a Gluten-Free Diet? Gluten-free means avoiding all foods containing gluten, including wheat, rye, spelt, bulgar, semolina, couscous, kamut and some oats. Gluten can be hidden in processed foods and thickened products such as sauces and soups so read labels carefully. While this can be an adjustment at first, eating gluten free if you are sensitive will make a huge difference in your health.     What’s the Difference between Celiac and Gluten Sensitivity? Celiac disease is an extreme intolerance to gluten where eating gluten will actually damage the lining of your intestines and cause mal-absorption along with many other symptoms such as all types of GI issues, skin issues, headaches, arthritis, depression and the list goes on and on. A gluten sensitivity is when you do not have full-blown celiac and your intestines are not completely damaged but eating gluten makes you feel worse and can often cause very similar if not the same symptoms of those with celiac disease.   What are the Problems with Celiac Testing (and Why is it so Hard to Get a True Answer)? Testing for this is very tricky because the occurrence of false negatives is often likely. The only way to get a true celiac test is to go to the GI doctor and have a biopsy. Your intestines are lined with hair like structures called villi and in healthy intestines; they stand straight up like a shaggy rug. When a person has celiac disease, gluten causes damage to the intestines and the villi lose their integrity and become flattened. The biopsy looks at the state of the villi and only if they are flattened can there be a true celiac diagnosis. Once gluten is removed from their diet, the villi can be revived fairly quickly and thus the intestines will heal.  Patients who already started a gluten free diet prior to their biopsy can often get a false negative because of this. To get a proper diagnosis, the patient should eat gluten (equivalent to at least 1 slice of wheat bread) every day for 30 consecutive days before the biopsy There is also a blood test that can identify the antibodies the body produces against gluten. Some GI doctors use this as a celiac test. The problem here is that the gluten antibodies are produced in significant numbers only if the person has a good functioning immune. With a weak immune system, antibody production will be low and lead to a false negative result. Furthermore, there are several types of antibodies that can be tested such and some of the main ones include IgE, IgG and IgA. IgE shows an immediate response and this often comes out negative unless someone has an anaphylactic shock type reaction to the food which is far less common. IgG and IgA are the delayed antibodies and are more likely to be found through testing because gluten-containing foods take several hours to several days to show symptoms and inflame the immune system.    Testing for Gluten Sensitivity When a celiac test is negative but someone feels worse after consuming gluten (this can happen from 1-72 hours post consumption) they most likely have a sensitivity to gluten. The reason the other tests are negative is because gluten reactions vary in strength. The easiest way to describe this is if you think of a spectrum from 0 to 100 with 0 being no sensitivity and 100 being extremely sensitive. If someone is all the way at 100 it would equate to celiac disease and/or extreme intolerance and often result in a positive biopsy but anything below that would not show up on those tests. So the problem is what if you are at 95? or 85? These cases would show up negative for celiac but as you can see from the example, 95 is still very high on the spectrum and the person would have a pretty severe sensitivity to gluten with all the same symptoms. Testing for sensitivities is also tricky because people can react to gluten through various allergenic pathways and being able to find a possible reactive pathway is the way to see a true result. The major proven pathways include antibody pathways and inflammatory cell mediated pathways. Antibodies can also be tested in blood, but only the IgA and IgG should be used (not IgE) as those are the delayed ones. IgA and IgG antibodies can also be tested in stool and saliva. There are different opinions on what is best (some say gluten is in contact with stool more than blood or saliva thus stool may be more accurate) but most likely testing in all 3, (blood, saliva and stool) is probably better. A positive result in any one of these means there is a sensitivity.    A Negative Gluten Sensitivity Test Does Not Rule Out Gluten Sensitivity It is possible that all 3 antibodies tested in all 3 body fluids can turn out negative but a reaction can still be occurring. This is possible because the body can react to gluten on a cellular level without necessarily producing antibodies, or if the antibody response is weakened due to immune weakness and other diseases. Another way to look at gluten sensitivity is through the inflammatory pathway of the white blood cells. The ALCAT technology has made their name in this area and they test by collecting blood, separating out the while blood cells and then introducing gluten to the white blood cells to look for information. If the while blood cell changes shape, the result is positive. The severity of the change in the white blood cell indicates the severity of the sensitivity. If there is no change to the white blood cell, there is no sensitivity. Persistent Gluten-Sensitivity Symptom Despite Negative Tests Another big piece of the gluten puzzle is a gluten intolerance due to the slight genetic change of the seeds of wheat. In Dr. William Davis's book Wheat Belly, he explains how a geneticist (about 50 years ago) was able to slightly modify the wheat seed to allow the wheat plant to grow faster and be harvested more often. This was lauded as a great help in the fight against world hunger but the genetic modification in the seed created a plant that now has a higher gluten content. Plants can naturally mutate from strain to strain over time but this process takes hundreds of years and this was done overnight. The human DNA is not familiar with this new strain of wheat and thus there are many people who are intolerant to this new wheat strain. Dr. Davis uses a wonderful analogy in his book to describe it. The new wheat is 99.9% genetically the same as the old wheat which doesn’t seem like it would be that harmful, but apes are also 99.9% genetically the same as humans and yet we are quite different. Intolerance to this genetically modified strain of wheat is not a blanket intolerance to gluten which is why eating it causes symptoms but a gluten sensitivity is not detectable in tests.   The Role of Genetics in Gluten Sensitivity and Gluten Intolerance Genetics are often ignored in the gluten intolerance discussion. Genes are something that you are born with and are carried down from generation to generation. There are a set of genes recognized as celiac genes and they are called HLA DQ2 and DQ8. We now know that the DQ2 gene has 2 pieces each with 2 alleles for a total of 4 and the DQ8 has 1 allele for a grand total of 5 different alleles. We need to see all of them. Studies show that if you have a specific number of these gene segments, your body is not designed to process certain gluten proteins and therefore you may have celiac disease already or will be likely to become gluten intolerant/sensitive. Gluten sensitivity is not a disease like celiac disease but can be looked at as a state of genetics. If a person is not designed to process gluten properly based on their genetics but eat it anyways, the end result is a constant attack on the immune system which can subsequently lead to autoimmune disease. But, if we knew a person’s propensity was to be gluten sensitive, we can stop the disease before it happens.   Testing for the Gluten Genes Most labs only do 2 of the gene pieces, but it is essential to have a complete profile of all of them. I have been searching for labs and found a panel that does all the pieces. They are a subsidiary of Labcorp so there is a good chance the test may even be covered by insurance which is a huge plus!   Best Test to Determine Gluten Intolerance The only way to know for sure if gluten is an issue for you is to look at all the pathways through various tests and if any are positive then you have an issue with gluten. Please don’t just take one negative result as an absolute - especially if you do not feel well when you eat gluten or if you have an autoimmune disease. After a lot of research, I believe that looking at genetics holds the biggest key in the gluten puzzle. All the other tests measure only a fraction of how a person’s immune system can react to gluten but genetics can actually tell us what the immune system is going to do in the future. You cannot control what genes you are born with, but you can identify them and change your diet and lifestyle to accommodate them to both heal a health issue as well as prevent a potential future health issue.     Eliminating Health Mysteries Could gluten be the root cause of your health mystery or that of someone in your life?  If you find that you don’t feel well when eating wheat at restaurants, this may be your issue. Eating organic wheat would be helpful for you as well as avoiding wheat when going out as most restaurants do not use organic wheat.    Links: Resources mentioned - tests for gluten sensitivity Alcat  Stool Test  Vibrant America Testing Genetic DQ2/DQ8 Testing   Related Podcast Episodes: #60 Demystifying Food Sensitivities (and What You Can do About Them)   Thanks for Listening If you like what you heard, please rate and review this podcast. Every piece of feedback not only helps me create better shows, it helps more people find this important information. Never miss an episode -  Subscribe NOW to Health Mysteries Solved with host, Inna Topiler on Apple Podcasts, Spotify, Stitcher or Google Podcasts and remember to rate and review the show! Find out more at http://healthmysteriessolved.com   PLEASE NOTE All information, content, and material on this podcast is for informational purposes only and is not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified physician or healthcare provider. Some of the links provided are affiliate links. This means we may make a very small amount of money should you choose to buy after clicking on them. This will in no way affect the price of the product but it helps us a tiny bit in covering our expenses.

This week, we’re talking about the many ports of Dragon Quest games! It’s a special request episode from our Patreon patron, Ty Robertson. We’re talking about our favorite (and least favorite) DQ ports, from GBC to DS to mobile to Switch. Whether your flavor is DQIII on the GBC or the new Switch one or even DQ8 on mobile, we want to talk about what these various ports bring to the DQ table. Thanks to Patreon patreon Ty Robertson for the show topic idea! Twitter: https://twitter.com/dragonquestfm Home: https://dragonquest.fm Patreon: https://patreon.com/dragonquestfm --- This episode is sponsored by · Anchor: The easiest way to make a podcast. https://anchor.fm/app --- Send in a voice message: https://anchor.fm/dragonquest/message Support this podcast: https://anchor.fm/dragonquest/support

In a very special episode of the GameBytes Show podcast, Jeremy is joined by one-time podcast cohost of yesteryear, Sean Kirkland from the Tech Gaming podcast! Jeremy and Sean bring that old-timey flair to the GBS podcast, giving "impressions" (the T-G term) of games we played this week. Sean starts the ball rolling with Dragon Quest 11, and we discuss its spiritual predecessor DQ8 and how they relate. Jeremy steers the show into Knights & Bikes, a new co-operative adventure games that embody the 1980s on lonely crummy islands in the North Atlantic. Intro: "I Wanna Ride My Bike" - Knights & Bikes, by Daniel Pemberton Outro: "Village Hidden In A Mountain" - Dragon Quest 11 ("good instruments" version) by Koichi Sugiyama Check out our Discord community at https://discord.gg/ZTzKH8y

The Case: Diana is 36 and suffers from irregular bowel movements and stomach upset. Endoscopies, colonoscopies and genetic testing for celiac disease provided no answers She tried adjusting her diet but nothing has helped and her doctor was stumped. My first suspicion was that her Celiac test was a false negative or that she had some underlying gluten-sensitivity. Gluten is found in wheat, rye, barley and oats and many people may have the sensitivity. It’s estimated that 30 – 40% of people are genetically positive for gluten-sensitivity. Many go undiagnosed. Dr. Peter Osborne is world renown in the field of gluten and grain sensitivity. He is the author   of the highly acclaimed bestseller, ‘No Grain, No Pain’ and is a Doctor of Chiropractic and board certified in clinical nutrition and pastoral medicine. He is the clinical director of Origins Healthcare in Sugarland, Texas and is also an advisor for Functional Medicine University. He joins me in the discussion of this case to share his significant expertise in this field. Confusion Around Gluten Terminology Many people mislabel conditions relating to gluten and mistakenly use gluten-sensitive, gluten-intolerant, gluten allergy, and celiac interchangeably. So, what is the difference between gluten sensitivity and gluten allergy? What’s the difference between gluten intolerance and celiac disease? Dr. Osborne explains that gluten sensitivity is a state of genetics which is not a disease. However, this sensitivity can lead to the development of celiac disease which is an autoimmune disease. Gluten intolerance is a reaction to gluten without the genetic disposition. The body cannot digest gluten properly because it is not producing the necessary enzyme. This can result in irritable bowel, gas, bloating and other intestinal discomforts. An allergy to gluten it very rare. Classically, this would show up as an acute response similar to other food allergies which often have symptoms like hives, swollen lips, and throat constriction. It’s potentially life-threatening. Traditional Testing for Celiac is Insufficient Most doctors will test two genetic markers for celiac disease but there are 5 antibodies that should be tested. Some people, like Diane, are told they don’t have Celiac disease and can eat gluten when that is not the case. Comprehensive tests that specifically include HLA DQ2 and DQ8 as well as the wheat zoomer (see below for links to these tests) are needed to completely rule out gluten issues. These tests are a simple cheek swab and a blood test. Gluten Sensitivity due to Genetics is Permanent While some people may feel better after giving up gluten for a period of time, this does not mean they can return to eating gluten. Dr. Osborne says that it can’t be reversed and his best advice is to stay away from it if they want to maintain their health. Eating gluten (for those that have the gluten genes) is unhealthy for them so if they go back to it, they’ll soon feel the repercussions of their unhealthy ways. Consider the Quality of Grains People who do not have the genetic markers for gluten sensitivity, antibodies to gluten, or the presence of autoimmune disease do not need to follow a gluten-free diet. However, it’s important to look at the quality of the food they’re eating. Grains can have mold or mycotoxins (see episode 006). They may also have trace amounts of pesticides that could include glyphosate which has been linked to cancer, neurodegeneration and fertility issues. In addition to that, many grains have been genetically modified. You Can’t Just Take a Pill There are enzymes available in supplement form that will help the body digest gluten. While this might seem like a ‘get out of jail free’ card, it’s not. If you have a gluten sensitivity or Celiac disease these are meant only to protect you against unwitting exposure (often through cross contamination in non-gluten-free restaurants or homes). It’s not a magic pill that you can take and then go devour a pizza. Sorry, guys. Eliminating Health Mysteries For Diana we were able to get to the real root of the problem and help her regain her health. Could a gluten sensitivity be the missing clue for you or someone in your life? Please share this episode with them so that they can feel better too. Links: Resources mentioned Thanks to my guest Dr. Peter Osborne. You can connect with him through his website: https://drpeterosborne.com/ You can get a copy of his book No Grain, No Pain here: www.glutenfreesociety.com   Thanks for Listening If you like what you heard, please rate and review this podcast. Every piece of feedback not only helps me create better shows, it helps more people find this important information. Never miss an episode –  Subscribe NOW to Health Mysteries Solved with host, Inna Topiler on Apple Podcasts, Spotify, Stitcher or Google Podcasts. Find out more at http://healthmysteriessolved.com   Overcoming Hashimoto’s Summit Claim your free spot to this 7-day virtual summit featuring the top experts in Hashimoto’s and Hypothyroidism so that you can overcome this diagnosis and feel better. https://bit.ly/2KigemW    PLEASE NOTE All information, content, and material on this podcast is for informational purposes only and is not intended to serve as a substitute for the consultation, diagnosis, and/or medical treatment of a qualified physician or healthcare provider. Some of the links provided are affiliate links. This means we may make a very small amount of money should you choose to buy after clicking on them. This will in no way affect the price the product but it helps us a tiny bit in covering our expenses.

Support this Podcast in 3 Clicks! In This Episode: Void is busy with life stuff, so Beej brings in Austin -- who you've probably heard about before. He is going to be blogging on the Geek to Geek site about playing through all of the Dragon Quest games this year, so we thought it would be a great time to bring him on the show to talk about the series. After discovering a love for DQ with the Dragon Quest Heroes games, DQXI grabbed both Austin and Beej and reeled them in hard. Without any previous mainline game experience, Austin decided to get the PS4 platinum trophy. By then he was hooked and was jonesing for as much DQ as he could get.  Dragon Quest XI - What's So Good About It We discuss at great length at why Dragon Quest XI stands out from so many other JRPGs, and why the game itself just works. Right now, it's a very traditional DQ game, but is honestly one of the most accessible RPGs out right now. There is true turn-based combat, a fantastic character named Sylvando you're going to love, and a lot of the jRPG classic gameplay but looks completely new and beautiful. Some folks complain about the music. But...it wasn't a problem for either of us. It was DQ music.  Other Dragon Quest Games Austin is currently playing Dragon Quest VII, which is different from the other games he's played. Right now, the game is very slow (16ish hours in), the characters are kinda obnoxious, but you can tell that it had a lot working against it back in the day when it was released on PS1. The 3DS version is definitely an improvement. DQ 1-3 on iOS are fantastic. And relatively quick to get through. They're known as the Erdrick Trilogy, and when you look at them versus Final Fantasy 1-3, you can actually tell how much more advanced the DQ games are than FF. It's around FFIV that the FF games really take off on their own and make their own way. Beej on Dragon Quest DQVIII was my first one. Saw @13th_story on Twitter post a picture, a single picture, from the 3DS version, and I went out and bought it. It just looked fun, and it was pretty, and I knew I had to play it. It took me a while to get into it, and I almost quit. I am very glad I didn't. Took me a while to get into it. Almost quit. Glad I didn’t. The game is super traditional but in the best way. DQ8 is absolutely a predecessor to DQXI, which is why XI is the better place to start now. It's the most improved of all the DQ games, has the most polish, and it doesn't ruin anything when you go back to the older ones.  Beej imported DQIX from Japan to practice the language. The DS version is the only version that exists. It didn't do so great in America. We both hope that XI's success will make them re-release a lot of these like IX with remasters.  What are your favorite Dragon Quest games? Let us know at @geektogeekcast. Get in touch with Austin at @austinkingbooks on Twitter and tell him what you think, too! Join Our Community! Discord: discord.geektogeekmedia.com Slack: slack.geektogeekmedia.com Reddit: reddit.com/r/geektogeekcast Subscribe iTunes | Overcast | Pocket Casts | Google Play Music | RSS Feed Geek to Geek Podcast Network Geek to Geek Geek Fitness Geektitude Tea Time with Katie and Chelsea TroytlePower CapsuleJay Austin's "Dragon Quest" Quest Music by CarboHydroM  

It had to happen eventually, I venture out on my own to talk about video game music. In this inaugural episode, I talk about some of my favorite introductory themes in games. Was there some things I had to leave out? Absolutely! Would you have wanted to listen to a three hour long podcast? Maybe […]

La Enfermedad Celiaca (EC) es una enfermedad sistémica inmunomediada, provocada por el gluten y prolaminas relacionadas, en individuos genéticamente susceptibles, y se caracteriza por la presencia de una combinación variable de: manifestaciones clínicas dependientes del gluten, anticuerpos específicos de EC, haplotipos HLA DQ2 o DQ8 y enteropatía. Esta definición fue actualizada por la ESPGHAN, Sociedad Europea de Gastroenterología Pediátrica, Hepatología y Nutrición en 2012.Hay diferentes tipos de EC: - Síntomática: Los síntomas son muy diversos pero todos los pacientes mostrarán una serología, histología y test genéticos compatibles con la EC.- Subclínica: En este caso no existirán síntomas ni signos, aunque sí serán positivas el resto de las pruebas diagnósticas.- Latente: Son pacientes que en un momento determinado, consumiendo gluten, no tienen síntomas y la mucosa intestinal es normal. Existen dos variantes:--Tipo A: Fueron diagnosticados de EC en la infancia y se recuperaron por completo tras el inicio de la dieta sin gluten, permaneciendo en estado subclínico con dieta normal.--Tipo B: En este caso, con motivo de un estudio previo, se comprobó que la mucosa intestinal era normal, pero posteriormente desarrollarán la enfermedad.-Potencial: Estas personas nunca han presentado una biopsia compatible con la EC pero, del mismo modo que los grupos anteriores, poseen una predisposición genética determinada por la positividad del HLA-DQ2/DQ8.Sintomatología de la Enfermedad CeliacaLos síntomas más frecuentes son: pérdida de peso, pérdida de apetito, fatiga, náuseas, vómitos, diarrea, distensión abdominal, pérdida de masa muscular, retraso del crecimiento, alteraciones del carácter (irritabilidad, apatía, introversión, tristeza), dolores abdominales, meteorismo, anemia por déficit de hierro resistentes a tratamiento. Sin embargo, tanto en el niño como en el adulto, los síntomas pueden ser atípicos o estar ausentes, dificultando el diagnóstico. La sensibilidad al gluten no celiaca es una nueva patología que sufren personas a las que se les ha descartado padecer la enfermedad celiaca y/o alergia al trigo, y que podrían sufrir entre un 5 y un 10 por ciento de la población. Pese a incluir el término gluten en el nombre de la nueva enfermedad, se desconoce si este componente del trigo, otras proteínas o los hidratos de carbono son los que desencadenan la sintomatología.Desde el punto de vista clínico, los afectados por esta nueva patología experimentan síntomas gastrointestinales como diarrea, dolor o hinchazón abdominal, aunque también predominan las manifestaciones extradigestivas como cansancio, dificultad para concentrarse y dolores musculares o articulares.Los anticuerpos antitransglutaminasa tisular son negativos y la mucosa intestinal muestra, en algunos casos, lesiones del tipo Marsh 1, aunque pueden no presentar ningún tipo de lesión.Los alérgicos al trigo, no lo son al gluten, solo al trigo y por ese motivo solo tendrán que retirar de su dieta este alimento.

La Enfermedad Celiaca (EC) es una enfermedad sistémica inmunomediada, provocada por el gluten y prolaminas relacionadas, en individuos genéticamente susceptibles, y se caracteriza por la presencia de una combinación variable de: manifestaciones clínicas dependientes del gluten, anticuerpos específicos de EC, haplotipos HLA DQ2 o DQ8 y enteropatía. Esta definición fue actualizada por la ESPGHAN, Sociedad Europea de Gastroenterología Pediátrica, Hepatología y Nutrición en 2012.Hay diferentes tipos de EC: - Síntomática: Los síntomas son muy diversos pero todos los pacientes mostrarán una serología, histología y test genéticos compatibles con la EC.- Subclínica: En este caso no existirán síntomas ni signos, aunque sí serán positivas el resto de las pruebas diagnósticas.- Latente: Son pacientes que en un momento determinado, consumiendo gluten, no tienen síntomas y la mucosa intestinal es normal. Existen dos variantes:--Tipo A: Fueron diagnosticados de EC en la infancia y se recuperaron por completo tras el inicio de la dieta sin gluten, permaneciendo en estado subclínico con dieta normal.--Tipo B: En este caso, con motivo de un estudio previo, se comprobó que la mucosa intestinal era normal, pero posteriormente desarrollarán la enfermedad.-Potencial: Estas personas nunca han presentado una biopsia compatible con la EC pero, del mismo modo que los grupos anteriores, poseen una predisposición genética determinada por la positividad del HLA-DQ2/DQ8.Sintomatología de la Enfermedad CeliacaLos síntomas más frecuentes son: pérdida de peso, pérdida de apetito, fatiga, náuseas, vómitos, diarrea, distensión abdominal, pérdida de masa muscular, retraso del crecimiento, alteraciones del carácter (irritabilidad, apatía, introversión, tristeza), dolores abdominales, meteorismo, anemia por déficit de hierro resistentes a tratamiento. Sin embargo, tanto en el niño como en el adulto, los síntomas pueden ser atípicos o estar ausentes, dificultando el diagnóstico. La sensibilidad al gluten no celiaca es una nueva patología que sufren personas a las que se les ha descartado padecer la enfermedad celiaca y/o alergia al trigo, y que podrían sufrir entre un 5 y un 10 por ciento de la población. Pese a incluir el término gluten en el nombre de la nueva enfermedad, se desconoce si este componente del trigo, otras proteínas o los hidratos de carbono son los que desencadenan la sintomatología.Desde el punto de vista clínico, los afectados por esta nueva patología experimentan síntomas gastrointestinales como diarrea, dolor o hinchazón abdominal, aunque también predominan las manifestaciones extradigestivas como cansancio, dificultad para concentrarse y dolores musculares o articulares.Los anticuerpos antitransglutaminasa tisular son negativos y la mucosa intestinal muestra, en algunos casos, lesiones del tipo Marsh 1, aunque pueden no presentar ningún tipo de lesión.Los alérgicos al trigo, no lo son al gluten, solo al trigo y por ese motivo solo tendrán que retirar de su dieta este alimento.

Ep. 293: Do I Have to Be Gluten-Free Forever? In this episode, Stacy and Sarah talk about if a little gluten now and then is so terrible for most people. Plus, they discuss genetic susceptibility to having issues with gluten. Click here to listen in iTunes   If you enjoy the show, please review it in iTunes! The Paleo View (TPV), Episode 293: Do I Have to Be Gluten-Free Forever? Intro (0:00) News and Views (0:40) Get ready listeners, this episode is loaded with bloopers at the end! Stacy is traveling and Sarah has a speaking engagement so they recorded this podcast a week early. Stacy is amazed at how her and Sarah's friendship has lasted because Sarah is so positive and enthusiastic, and Stacy is sardonic and sarcastic! Stacy and family are headed off on a cruise, which was the boys' Christmas gift. They are all unplugging, not getting wifi on the ship. Stacy has been trying to prepare ahead for this! The boys chose Jamaican bobsledding as an excursion, which Stacy is crazy excited for! Sarah is looking forward to nerding-out on Jamaican bobsled history with them! The boys have never been out of the country before, they had to get passports. After the cruise they are going to visit the Kennedy Space Center and then head over to Sarah's house. Sarah is planning Kalua Pork and Stacy requested Ambrosia Salad. Sarah chaperoned a sleep-away field trip a couple weeks ago with her daughter's class. She had an amazing experience and it was great bonding time with her daughter. It was long, exhausting days but she loved the curriculum and everything they learned. She is still catching up on sleep. Listener Question (16:27) Gina asks, "Since late last year I have started listening to your podcast and I LOVE all the information you both share.. I have gone back and listened to so many old podcasts. My question for you is late last year I started seeing a registered dietitian to help lose weight (20 pounds overweight). I am active and eating for the most part a clean diet. I have not adapted a Paleo Diet as I eat very little meat protein. I am obsessed with eating healthy reading labels and trying to feed my family as healthful as possible.I had a Vibrant Wellness sensitivity test done I had 3 positive foods and 9 Moderate foods, Gluten Containing Grains and Gluten Free grains were among that list. With this information I had the gene test done for Celiac and I tested positive for the DQ8. And then also further had a wheat zoomer test done that, that came back showing some high risk for some of these panels. I was told I have leaky gut and to avoid gluten now for LIFE ahhhh.My husband and sister were also tested and both carrying a celiac gene. I just read your post on The Celiac Gene and am still confused. Do I need to avoid gluten forever, can I have some every once and awhile? I never noticed any symptoms that bothered me. When on vacation recently I did have pasta that wasn't GF. I didn't feel great after that but nothing that would stop me from eating again. I feel less bloated but not seeing weight loss. I don't do well with being told NOT to have something. Will I develop Celiac disease if I continue to eat it gluten? Are my kids at risk since my husband and I both carry this gene?I know you both talk about that you and your family are gluten free, I just don't know that I can do this 100% of the time. Is this really going to affect my body if we continue to allow some gluten in our diet? Any help or suggestions would be greatly appreciated!!!!" Stacy says that if it were her and she found out she had a hereditary disposition to gluten, she wouldn't personally eat it. Stacy is also a control freak and doesn't like being told what to do. She tells herself that she is choosing not to eat gluten, not that she "can't." Sarah doesn't subscribe to the dogma of everyone must be 100% gluten free all the time. The idea that we haven't adapted to eating modern foods is oversimplified. She talks in depth in Paleo Principles about a study that compared genes over time, and they did find genetic adaptation in some areas. One example is that some people have adapted to producing lactase into adulthood, called lactase persistence, which depends largely on your heritage. The Celiac genes HLADQ2 and HLADQ8 are genetic adaptations related to the advent of agriculture. This probably indicates we have had some adaptations to modern agriculture. There is an incomplete understanding of how we've adapted to neolithic foods. This suggests that not everyone needs to be gluten free 100% of the time. Gluten-containing foods are not nutrient-dense foods. There is a definitive link now between gluten and weight-gain. There are other inflammatory compounds in gluten. Wheat germ agglutinin can carry across the gut barrier and is highly inflammatory. There isn't a case to be made that gluten is a health food. There is evidence that some people can tolerate gluten. Gluten is inflammatory in all of us. Even if you can tolerate gluten with no obvious affects, it is not a health-promoting food. Gluten can affect people in a multitude of ways, from acne, sinus congestion, headaches, joint pain... it isn't just bloating and gut symptoms. Many people use travel as an excuse to consume gluten, which seems the opposite of what you might want- to feel your best and have a great immune system when exposed to germs. Stacy likes to test the waters with her grey-area foods when she knows she can deal with the consequences like joint pain or skin breakouts. The difference in people who can tolerate gluten on occasion and people who can't touch it with a 10-foot pole is complex and has to do with magnitude of symptoms and recovery time. Implications of gluten consumption in non-Celiacs with Celiac risk genes is an important topic. 97% of Celiac disease sufferers have one or both gene variants. These genes relate to zonulin production. Zonulin is released by the gut cells when we eat gluten (in everyone.) It acts on the tight junctions between the cells of the intestines. This increases intestinal permeability, which allows things to get into the body which shouldn't be in the body. In Celiac disease this response is magnified, which allows all kinds of things into the body. This drives body-wide inflammation. Recent studies have show that those with the Celiac genes but not diagnosed with Celiac disease have the same magnified reaction to gluten with zonulin production. This may happen in everyone with one or both of genes. How prevalent is this? In North America 55% may have one of these genetic variations. These genes are also associated with other autoimmune diseases and health problems. There science is pretty conclusive that this 55% that have genetic susceptibility to Celiac disease are going to have health problems related to gluten consumption. How do you live your life and feed your family 100% gluten free. Reading labels is a great start! Learn to be assertive with eating out and talking to restaurant staff, asking them to double check. Being prepared is important- always pack protein and gluten-free snacks. Stacy's family loves: Rx Bars Beef jerky and meat sticks like Roam and Chommps Paleo Power Balls Epic Pork Rinds Research ahead of time where you are traveling to or will be eating at. Cooking at home and replacing grains with more vegetables, fats and proteins means you will win on the nutrient front. There are gluten-free replacements for just about anything- these make great transitions foods. Know your currency food, if you can just have that one thing, everything else will be easier. For Sarah this is chocolate and coffee. If your currency is a grilled cheese sandwich on gluten-free bread on Sunday afternoon and that's what it takes to keep you going the rest of the week, then that's okay. It does get better and easier the more you eat that way. There are so many tools available for going gluten-free now, that weren't there even 5 years ago. The more you focus on the good that is happening in your body, the purpose, and what you can have, the easier it becomes. We hope you all have a lovely spring break- whether you are traveling or having a staycation. If you've enjoyed the show, please recommend it to someone who might enjoy it. We love when you share and when you leave reviews for us! Thanks for listening! Real Everything The Paleo Mom Support us by shopping through links on our sidebars- thanks!

This time on the ‘Gluten Free RN’ podcast, Nadine explores the connection between gluten intolerance and antibiotic-resistant threats. Because damaged intestines compromise the immune system, undiagnosed celiac patients are more likely to develop infections that necessitate antibiotics.  Nadine summarizes the 2013 CDC report, Antibiotic Resistance Threats in the United States, explaining the three microorganisms identified in the report with a Threat Level of Urgent. Listen and learn how to protect yourself and your family from the public health threat posed by these bacteria!  What’s Discussed:  The prevalence of undiagnosed celiac disease and gluten intolerance 30-50% of the population carry the HLA-DQ2 and/or DQ8 genes The importance of healthy intestinal tissue 70-90% of the immune system is in your intestines The soldier analogy Healthy villi are like rested soldiers with loaded weapons on a clear day who can easily take out antigens that don’t belong Damaged villi are like soldiers on a bender with inadequate weaponry, operating in smoke and fire – they either don’t work at all or fire randomly at antigens The need for a more judicious approach to prescribing antibiotics Overuse of antibiotics wipes out good microbiome along with bad How to rebuild microbiome Kombucha High-quality probiotics Fermented foods Apple cider vinegar The need for IgA and IgG testing to complement a celiac panel The public health threat posed by antibiotic-resistant bacteria The 2013 CDC report details 2 million illnesses and 23,000 deaths yearly The connection between damaged intestines and a higher risk of bacterial infection requiring antibiotics The three microorganisms with a Threat Level of Urgent Clostridium difficile (causes profuse diarrhea, 14,000 deaths/year) Carbapenem-resistant Enterobacteriaceae (50% fatal, 600 deaths/year) Neisseria gonorrhoeae The causes of inflammation in your intestines Gluten Dairy Sugar Why Nadine has concerns about the potential pandemic and huge loss of life presented by large numbers of undiagnosed celiac patients who are susceptible to bacterial infections  Resources Mentioned:   CDC Report: Antibiotic Resistance Threats in the United States, 2013 Enterolab Website Cyrex Laboratories Website PubMed Connect with Nadine:  Instagram Facebook Contact via Email Books by Nadine: Dough Nation: A Nurse's Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism

This time on ‘Gluten Free RN,’ Nadine continues to cover the basics of celiac disease and gluten intolerance, reviewing the consequences of intestinal damage and gluten in the bloodstream and discussing what you can and cannot eat as part of a gluten-free diet. A registered nurse certified in emergency care and a celiac patient herself, Nadine is well-versed in the health complications and symptoms you might experience with undiagnosed celiac disease or gluten intolerance, including neurological disorders, dermatologic difficulties and even mental health issues. Join the Gluten Free RN on this podcast to learn the signs of undiagnosed celiac disease and gluten intolerance so that we can all be healthy and vital for years to come! What’s Discussed:  The definition of celiac disease and its chronic nature Diagnosis requires HLA-DQ2 and/or DQ8 genes and documented villous atrophy The importance of healthy intestinal tissue 70-90% of the immune system is in your intestines Grains to avoid that contain gluten Wheat Barley Rye Oats (due to cross-contamination) Places where gluten may be hiding Gluten-free, nutrient dense foods Complications caused by gluten in patients with celiac disease or gluten intolerance Chronic inflammation (suffering from an -itus of any kind) Autoimmune disorders Damaged immune system Malnutrition/deficiencies The increased risk of cancer in patients with undiagnosed celiac disease Symptoms doctors look for before testing for celiac disease Chronic diarrhea Malabsorption Extreme weight loss or malnutrition Components of the test for celiac disease Blood test (celiac panel) Biopsy of the small intestines The amount of time it takes to regenerate damaged villi in the absence of gluten Nadine recommends you continue the clinical trial of a gluten-free diet for at least six to 12 months Additional signs of a possible gluten intolerance or celiac disease Additional symptoms Nadine has encountered in undiagnosed patients Indicators of gluten intolerance in children and elders Resources Mentioned:  Montana Gluten Free Website Kite Hill Non-Dairy Foods Gluten: Zero Global by Rodney Ford Connect with Nadine:  Instagram Facebook Contact via Email Books by Nadine: Dough Nation: A Nurse's Memoir of Celiac Disease from Missed Diagnosis to Food and Health Activism

Prepare the tea and bring out that fancy gluten-free dessert while you listen to Hamed and Andy talk about the basics of Coeliac disease! **Error during podcast**- HLA DQ2, DQ8 are responsible to create recognition sites for MHC class II.