Podcasts about ios devices

Last week, the National Multiple Sclerosis Society and the European Committee for Treatment and Research in Multiple Sclerosis convened a meeting in Dublin, Ireland, to dive deeper into what a new framework for describing MS might look like.   There's still a tremendous amount of work to be done here. But, considering that whatever language is eventually adopted will affect every person living with MS, I want to keep you fully informed on this important work. So I'm devoting this entire episode of the podcast to sharing conversations I had with three of the attendees at the meeting in Dublin.    First, you'll hear from Dr. Bruce Bebo, the National MS Society's Executive Vice President of Research. Then, you'll hear from Dr. Daniel Ontaneda, a neurologist specializing in MS at the Cleveland Clinic, and, finally, you'll hear from Kathy Smith, who's lived with MS for the past 20 years.   As you listen to these conversations, I think you'll hear three slightly different perspectives, but you'll also hear some of the broad concepts and ideas around which there was a high level of agreement at our meeting. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: A meeting to discuss moving to a biologically based description of MS  :22 Dr. Bruce Bebo discusses how a new framework for describing MS could impact MS research and people living with MS  3:45 Dr. Daniel Ontaneda describes some of the shortcomings of the current MS course descriptors and discusses how a new framework for describing MS could impact   people living with MS  17:34 Kathy Smith explains how current MS course descriptors fail to fully capture her experience as someone living with MS, and explains how new course descriptors could benefit people living with MS  26:24 What's next in the work to develop new course descriptors for MS  35:20 Share this episode  35:44 Have you downloaded the free RealTalk MS app?  36:03 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/403 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS Episode 279: A New Framework for Researching, Diagnosing, and Treating MS with Professor Tanja Kuhlmann https://realtalkms.com/279 RealTalk MS Episode 280: How the Proposed Framework for Diagnosing and Treating MS Will Affect You with Dr. Tim Coetzee https://realtalkms.com/280 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 403 Guests: Dr. Bruce Bebo, Dr. Daniel Ontaneda, Kathy Smith Privacy Policy

If you're living with MS, you might experience days when it feels like you're losing your sense of who you are, as your sense of self gets redefined by your symptoms. Reasserting your personal style can be a powerful way to rediscover joy in who you are while reclaiming your identity.    Jeri Zink Denz lives with MS and works in the luxury fashion industry. She's always been passionate about fashion and personal style, and Jeri joins me to discuss how you can find and define your personal style, despite the challenges that MS may present. We'll also explain the hidden outcome of the massive agency layoffs and drastic cuts in federal funding for healthcare research, and this is the outcome that can affect research for decades to come. We're sharing the results of a study that may have identified a biomarker for rapid MS progression. We'll tell you about the game-changing artificial intelligence project that received a $750,000 investment from the International Progressive MS Alliance. And you'll find out how and where you can register for the upcoming Hispanic/Latinx MS Experience Summit. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Reasserting your personal style can be a powerful way to rediscover joy in who you are in spite of the challenges that MS may present.   :22 Layoffs + funding cuts = brain drain  1:08 Have researchers found a biomarker for rapid MS progression?  4:51 The International Progressive MS Alliance has invested $750,000 in what could be a game-changing AI project  9:09 The National MS Society's Hispanic/Latinx MS Experience Summit is just 8 days away  10:59 Jeri Zink Denz discusses why it's especially important (and even therapeutic!) to assert your personal style when you're living with MS  12:22 Share this episode  29:31 Have you downloaded the free RealTalk MS app?  29:50 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/402 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Become an MS Activist Web: https://nationalmssociety.org/advocacy Email: msactivist@nmss.org STUDY: Broad Rim Lesions are a New Pathological and Imaging Biomarker for Rapid Disease Progression in Multiple Sclerosis https://nature.com/articles/s41591-025-03625-7 International Progressive MS Alliance https://progressivemsalliance.org Hispanic/Latinx MS Experience Summit Info & Registration https://nationalmssociety.org/resources/get-support/education-programs-and-library/hispanic-latinx-ms-experience Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 402 Guest: Jeri Zink Denz Privacy Policy

Most people living with MS don't see their neurologist often. For many, it might be only once or twice a year. A lot of important things take place during that appointment. Symptoms are assessed. Decisions about disease-modifying therapies are made or, sometimes, changed. Questions get asked and, hopefully, answered.   Dr. Barbara Giesser returns to the podcast, this time, to review the things that should be discussed and followed up on at your appointment with your neurologist or MS specialist. We're also sharing some good news about MS research funding from the National MS Society and the International Progressive MS Alliance. We'll tell you how you can catch the replay of the International Progressive MS Alliance's webcast focused on putting people with MS at the center of MS research. We're sharing the encouraging outcome of the Phase 2 clinical trial for vidofludimus calcium and progressive MS. We'll tell you how you or a family member can participate in the GEMS study. And we'll tell you about a new AI tool that can accurately diagnose a patient's transition from relapsing-remitting MS to secondary progressive MS, often before a clinician can! We have a lot to talk about! Are you ready for RealTalk MS??! This Week: What (should) happen during your appointment with your neurologist  :22 National MS Society invests $18.1 million in new research  1:04 International Progressive MS Alliance funds 3 clinical trial development projects  3:53 Catch the replay of the International Progressive MS Alliance webcast focused on putting people with MS at the center of research  6:56 Immunic Therapeutics announces positive results from the Phase 2 clinical trial evaluating vidofludimus calcium for progressive MS  7:45 You or a family member may qualify to participate in the GEMS study  10:00 AI tool can accurately diagnose the transition from relapsing-remitting MS to secondary progressive MS  12:01 Dr. Barbara Giesser discusses the kinds of conversations you should be having during your appointment with your neurologist  16:49 Share this episode  30:38 Have you downloaded the free RealTalk MS app?  31:00 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/401 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Become an MS Activist Web: https://nationalmssociety.org/advocacy Email: msactivist@nmss.org National MS Society Commits $18.1 Million for Research (Projects Being Funded) https://cdn.sanity.io/files/y936aps5/production/a788b2e3d8409173a4de417fcf3bebcfbddddc41.pdf International Progressive MS Alliance https://progressivemsalliance.org International Progressive MS Alliance Webcast: Putting People with MS at the Center of Research https://youtube.com/watch?v=uacSJ7ZxuRM Participate in MS Research: The GEMS Study https://recruit.cumc.columbia.edu/studyinfopage/1419 GEMS Study Contact: Juliana Oyegunle Email: gems_neuro@cumc.columbia.edu Phone: (212) 305-2434 STUDY: Conformal Prediction Enables Disease Course Prediction And Allows Individualized Diagnostic Uncertainty in Multiple Sclerosis https://www.nature.com/articles/s41746-025-01616-z Multiple Sclerosis Progression Tracker https://msp-tracker.serve.scilifelab.se/ Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 401 Guests: Dr. Barbara Giesser Privacy Policy

Welcome to the 400th episode of RealTalk MS! Over the past nearly eight years, it's been my absolute honor to bring you insights from leading experts, researchers, advocates, and, perhaps most importantly, from people living with MS themselves. And we have no intention of stopping here! We're excited to continue bringing you the information and conversations that matter most to the MS community.   In this episode of the podcast, Dr. Tim Coetzee, President and CEO of the National MS Society, looks back at a significant milestone that took place eighty years ago. Tim also shares his detailed vision of the future for people living with MS, and discusses some of the cutting-edge MS research that he's most excited about. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Welcome to episode 400!  :18 Dr. Tim Coetzee, President and CEO of the National MS Society, looks back at the past, shares his vision of the future, and discusses the MS research that he's most excited about  2:32 Share this episode  30:31 Have you downloaded the free RealTalk MS app?  30:50 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/400 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Become an MS Activist Web: https://nationalmssociety.org/advocacy Email: msactivist@nmss.org Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 400 Guests: Dr. Tim Coetzee Privacy Policy

Research shows that spirituality can benefit mental health and improve overall well-being. And it can play a meaningful role in helping people cope with life's challenges, like living with MS. This week, Dr. Mana Ali Carter, a rehabilitation psychologist at MedStar National Rehabilitation Hospital in Washington D.C., joins me to discuss the positive effects that spirituality can have on the mind and body, and how it's been shown to make a difference for people living with MS.   We're also sharing encouraging initial reports from a Phase 1 clinical trial for KYV-101, Kyverna's investigational CAR-T therapy for MS. We'll tell you about a positive report on two years of data from a Phase 2 clinical trial extension study for Frexalimab, a novel investigational disease-modifying therapy from Sanofi. We'll explain how the decision to discontinue federal matching funds for designated state health programs will have a direct impact on some people living with MS. And we'll tell you how you can register for the National MS Society's webinar in support of restoring federal funding for the MS Research Program. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: How spirituality can make a difference if you're living with MS  :22 Initial reports from a Phase 1 clinical trial for a CAR-T therapy are encouraging  1:15 Two years of data from a Phase 2 extension study of Frexalimab are positive  3:07 The federal government will no longer provide matching funds for designated state health programs  5:47 The National MS Society is hosting a virtual event to support restoring federal funding for the MS Research Program  8:38 Dr. Mana Ali Carter explains how spirituality can make a difference in your life if you're living with MS  11:27 Share this episode  30:40 Have you downloaded the free RealTalk MS app?  31:01 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/399 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Become an MS Activist Web: https://nationalmssociety.org/advocacy Email: msactivist@nmss.org Participate in a Sanofi Clinical Trial https://sanofistudies.com Register for a Virtual Event: Restore the MS Research Program https://nmss.quorum.us/event/23043 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 399 Guests: Dr. Mana Ali Carter Privacy Policy

Last week, at the American Academy of Neurology annual meeting, Dr. Amit Bar-Or received the John Dystel Prize for Multiple Sclerosis Research for his multiple achievements that have advanced our knowledge of neuroimmunology, precision medicine, and biomarkers in MS. We talked with Dr. Bar-Or about how some of the latest discoveries in MS research would impact patient care.   Tolebrutinib, an investigational disease-modifying therapy, is currently making its way through the FDA's regulatory process. Last week, the results of the Phase 3 clinical trials for Tolebrutinib were published, and we're sharing the details. We'll also tell you about MindGlide, an AI-powered tool for analyzing MRI scans that will significantly reduce MRI exam times. We're talking about the results of the Phase 3 clinical trial for high-dose Ocrevus. And we'll tell you about a cell therapy that doesn't use stem cells that successfully repaired myelin in the mouse model of MS -- twice!  We have a lot to talk about! Are you ready for RealTalk MS??! Congratulations to Dr. Stephen Hauser and Dr. Alberto Ascherio  :22 This Week: The impact of breakthrough MS research on MS care  2:17 Results of the phase 3 clinical trials for Tolebrutinib have been published  3:07 An AI-powered tool for analyzing MRI scans will significantly reduce MRI exam times for patients  4:21 Results of the phase 3 clinical trial for high-dose Ocrevus  8:13 A cell therapy that doesn't use stem cells has successfully repaired myelin in the mouse model of MS -- twice!  10:14 Dystel Prize winner Dr. Amit Bar-Or discusses how some of the latest discoveries in MS  research will impact MS care  12:39 Share this episode  22:36 Have you downloaded the free RealTalk MS app?  22:56 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/397 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Become an MS Activist Web: https://nationalmssociety.org/advocacy Email: msactivist@nmss.org RealTalk MS Episode 310: The Face Laughs While The Brain Cries: The Education of a Doctor with Dr. Stephen Hauser https://realtalkms.com/310 RealTalk MS ECTRIMS Extra: Results from the Phase 3 Clinical Trial for Tolebrutinib and Relapsing-Remitting MS with Dr. Jiwon Oh https://realtalkms.com/ectrims244 VIDEO: RealTalk MS ECTRIMS Extra: Results from the Phase 3 Clinical Trial for Tolebrutinib and Relapsing-Remitting MS with Dr. Jiwon Oh https://youtu.be/zcBmAHRTotA VIDEO: RealTalk MS ECTRIMS Extra: Results from the Phase 3 Clinical Trial for Tolebrutinib and Nonrelapsing Secondary Progressive MS with Dr. Robert Fox https://youtu.be/tJQ93qdlXrU STUDY: Tolebrutinib Versus Teriflunomide in Relapsing Multiple Sclerosis https://nejm.org/doi/full/10.1056/NEJMoa2415985 STUDY: Tolebrutinib in Nonrelapsing Secondary Progressive Multiple Sclerosis https://nejm.org/doi/full/10.1056/NEJMoa2415988 Enabling New Insights from Old Scans By Repurposing Clinical MRI Archives for Multiple Sclerosis Research https://www.nature.com/articles/s41467-025-58274-8 Fibroblast Technology https://fibrobiologics.com/technology/#cnsms Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 398 Guests: Dr. Amit Bar-Or Privacy Policy

For many people, it can be difficult to talk about the feelings of loss that can accompany MS. For some, it's the loss of the way they imagined their life would turn out. For others, it's the more specific loss of function. Perhaps the loss of their mobility. Or a decline in their cognitive skills. It's painful to imagine any of these scenarios, let alone experience them in real life.    The human response to loss is grief. And grieving itself can affect your physical, emotional, and cognitive health. Joining me today to discuss how grieving can affect you, along with ways to best manage grief, is Dr. Mary-Frances O'Connor. Dr. O'Connor is a professor of psychology at the University of Arizona, where she directs the Grief, Loss, and Social Stress Lab, investigating the effects of grief on the brain and the body. Dr. O'Connor also lives with MS, and the title of her new book is The Grieving Body: How the Stress of Loss Can Be an Opportunity for Healing. We'll also share the results of a study on MS fatigue in Finland. We'll tell you about a study that focused on sexual dysfunction among women living with MS in Iran. You'll learn what a research team discovered when they connected sick days from work with the prodromal phase of MS. And we're sharing a new resource from the MS International Federation that will help you assess which wellness practices and complementary therapies may be beneficial for you. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Managing the grief that comes from living with MS  :22 Results from a Finnish study adds further evidence to what we know about MS fatigue  1:36 Results of a study that focused on sexual dysfunction among women living with MS in Iran  3:13 Can job-related sick days help researchers better understand the prodromal phase of MS?  5:48 The MS International Federation has produced a very worthwhile guide to wellness practices and complementary therapies for people with MS  10:49 Dr. Mary-Frances O'Connor discusses managing the grief that accompanies being diagnosed with MS  12:42 Share this episode  34:02 Have you downloaded the free RealTalk MS app?  34:22 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/397 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Become an MS Activist Web: https://nationalmssociety.org/advocacy Email: msactivist@nmss.org STUDY: Evaluation of Patient-Perceived Fatigue in Multiple Sclerosis Using the Finnish MS Registry https://journals.sagepub.com/doi/10.1177/20552173251325098 STUDY: The Prevalence of Sexual Dysfunction and Its Contributors Among the Women with Multiple Sclerosis https://bmcwomenshealth.biomedcentral.com/articles/10.1186/s12905-025-03653-y STUDY: The Prodromal Phase of Multiple Sclerosis: Evidence from Sickness Absence Patterns Before Disease Onset -- A Matched Cohort Study https://jnnp.bmj.com/content/early/2025/03/25/jnnp-2024-335279.full STUDY (PLAIN ENGLISH VERSION): The Prodromal Phase of Multiple Sclerosis: Evidence from Sickness Absence Patterns Before Disease Onset -- A Matched Cohort Study https://tremlettsmsresearchexplained.wordpress.com/2025/03/26/the-prodromal-phase-of-multiple-sclerosis-evidence-from-sickness-absence-patterns-before-disease-onset-a-matched-cohort-study-explained DOWNLOAD: Wellness Practices and Complementary Therapies in MS https://msif.org/resources/wellness-practices-and-complementary-therapies/ Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 397 Guests: Dr. Mary-Frances O'Connor Privacy Policy

Managing MS means staying focused not only on your MS but also on your overall health. That includes getting routine health screenings to stay ahead of potential complications. Recent research has shown that, compared to healthy people, people with MS are more likely to develop some cancers.    Clinician-scientist Dr. Ruth Ann Marrie joins me to discuss which cancers pose a greater risk to someone with MS, why you need to make those appointments for cancer screenings, where you can find low-cost or no-cost cancer screenings, and things you can do to further minimize your risk of developing cancer. Dr. Marrie is a professor of medicine and the Multiple Sclerosis Clinical Research Chair at Dalhousie University in Canada. She's a past recipient of the Barancik Prize for Innovation in MS Research and is recognized as one of the world's leading MS experts. We'll also explain how and why we're going to be discussing the impact of those devastating federal budget cuts and mass layoffs in the federal agencies responsible for healthcare and MS research on this podcast. We'll tell you about the FDA's decision to grant priority review to Tolebrutinib. (We'll also explain why Tolebrutinib isn't just another DMT. We're even sharing the projected date when the FDA will make its approval decision!) And you'll learn what happened when a research team set out to identify the diversity-related characteristics of the MS population in Canada. We have a lot to talk about! Are you ready for RealTalk MS??! How we'll be talking about the impact of public policy on people affected by MS (and why we must)  :22 Hear what's on the minds of some of the attendees at last week's National MS Society Public Policy Conference  3:55 This Week: The importance of cancer screenings for people with MS  12:52 Tolebrutinib, an investigative DMT from Sanofi, is granted priority review by the FDA  13:44 What happened when researchers set out to identify the diversity-related characteristics of the MS population in Canada  17:56 Dr. Ruth Ann Marrie discusses the importance of cancer screenings for people living with MS  20:02 Share this episode  30:03 Have you downloaded the free RealTalk MS app?  30:23 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/396 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Become an MS Activist Web: https://nationalmssociety.org/advocacy Email: msactivist@nmss.org VIDEO: Tolebrutinib and Non-Relapsing Secondary Progressive MS with Dr. Robert Fox https://realtalkms.com/tolebrutinib1 VIDEO: Tolebrutinib and Relapsing-Remitting MS with Dr. Jiwon Oh https://realtalkms.com/tolebrutinib2 VIDEO: RealTalk MS 2025 ACTRIMS Forum YouTube Playlist https://realtalkms.com/actrims STUDY: Characterizing the Diversity of the Multiple Sclerosis Population in Canada: A Scoping Review https://journals.sagepub.com/doi/10.1177/20552173251321814 STUDY (PLAIN ENGLISH VERSION): Characterizing the Diversity of the Multiple Sclerosis Population in Canada: A Scoping Review https://tremlettsmsresearchexplained.wordpress.com/2025/03/20/characterizing-the-diversity-of-the-multiple-sclerosis-population-in-canada-a-scoping-review-explained Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 396 Guests: Dr. Ruth Ann Marrie Privacy Policy

When you look at a list of the typical symptoms associated with perimenopause, you'd think you were looking at a list of MS symptoms. And, for women living with MS, that's where the confusion begins. With an estimated 30% of the current MS population now in peri- or post-menopause, researchers are beginning to focus on how menopause and MS interact and the best ways to treat symptoms.   Dr. Riley Bove, a neurologist and founding director of the Sex and Gender-Enriched (SAGE) Neurology Program at the University of California San Francisco, joins me to talk about the things you need to know when you're managing MS while you're managing menopause. We'll also tell you about this year's winner of the John Dystel Prize for Multiple Sclerosis Research. We'll share a deeply personal poem written by a friend who's been living with MS since 1988. And we'll tell you about the results of a study that should be a reminder of the importance of starting disease-modifying therapy and the value of early intervention. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: We're in Washington, D.C., at the National MS Society's Public Policy Conference  :22 Dr. Amit-Bar-Or is the winner of the 2025 John Dystel Prize for Multiple Sclerosis Research  2:26 Magician Wayne Dobson's poem  7:07 STUDY: Cognitive impairment is prevalent among people living with untreated MS  10:23 Dr. Riley Bove talks about the things you need to know when you're managing MS while you're managing perimenopause and menopause  14:18 Share this episode  32:56 Have you downloaded the free RealTalk MS app?  33:16 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/395 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Become an MS Activist Web: https://nationalmssociety.org/advocacy Email: msactivist@nmss.org RealTalk MS 2025 ACTRIMS Forum YouTube Playlist https://www.youtube.com/playlist?list=PLATxgj1uHpxNEoc2-9_7-Wzmr96B7wt2C Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 395 Guests: Dr. Riley Bove Privacy Policy

Next week, a couple of hundred MS activists will gather in Washington, D.C. for the National MS Society's Public Policy Conference. As we're seeing devastating cuts in funding for MS research, layoffs in every major governmental agency that impacts our healthcare, including the National Institutes of Health, the FDA, CDC, Health and Human Services, and the Department of Veterans Affairs, and even Medicaid funding is at serious risk, advocacy has never been more important than it is right now.    I'm devoting this entire episode to a conversation with Steffany Stern, the National MS Society's Vice President for Advocacy, who joins me to assess the current legislative climate in Washington, D.C., and give us a preview of the issues that will take center stage at this year's Public Policy Conference.  We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Is there anything more urgent and important to discuss than advocacy?  :22 Steffany Stern discusses the current legislative climate in our nation's capitol, and gives us a sneak peek at next week's National MS Society Public Policy Conference  2:16 Share this episode  25:40 Have you downloaded the free RealTalk MS app?  26:08 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/394 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Become an MS Activist Web: https://nationalmssociety.org/advocacy Email: msactivist@nmss.org RealTalk MS 2025 ACTRIMS Forum YouTube Playlist https://www.youtube.com/playlist?list=PLATxgj1uHpxNEoc2-9_7-Wzmr96B7wt2C Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 394 Guests: Steffany Stern Privacy Policy

Just a couple of weeks ago, 1,800 scientists, clinicians, postdoctoral fellows, and medical residents gathered in West Palm Beach, Florida, for the Americas Committee for Treatment and Research in Multiple Sclerosis annual meeting, better known as the ACTRIMS Forum. Dr. Emanuelle Waubant is a neurologist who specializes in treating patients with MS, and she is the Director of the UCSF Regional Pediatric Multiple Sclerosis Center. At the ACTRIMS Forum, we talked with Dr. Waubant about advances in pediatric MS treatment and care, and the importance of the International Women in Multiple Sclerosis organization. We have a lot to talk about! Are you ready for RealTalk MS??! SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/actrims07 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Bonus Episode Guest: Dr. Emanuelle Waubant Privacy Policy

Just a couple of weeks ago, 1,800 scientists, clinicians, postdoctoral fellows, and medical residents gathered in West Palm Beach, Florida, for the Americas Committee for Treatment and Research in Multiple Sclerosis annual meeting, better known as the ACTRIMS Forum. Kristine Werner Ozug lives with MS and, full disclosure, she's a member of the RealTalk MS team. After the ACTRIMS Forum, Kristine shared her impressions of the conference. We have a lot to talk about! Are you ready for RealTalk MS??! SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/actrims08 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Bonus Episode Guest: Kristine Werner Ozug Privacy Policy

Just a couple of weeks ago, 1,800 scientists, clinicians, postdoctoral fellows, and medical residents gathered in West Palm Beach, Florida, for the Americas Committee for Treatment and Research in Multiple Sclerosis annual meeting, better known as the ACTRIMS Forum. Dr. Mikael Simons is a neurologist and researcher at Technical University Munich and the Centre for Neurodegenerative Diseases in Munich, Germany, and he's this year's recipient of the Barancik Prize for Innovation in MS Research. At the ACTRIMS Forum, we talked with Dr. Simons about his research in myelin repair. We have a lot to talk about! Are you ready for RealTalk MS??! SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/actrims06 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Bonus Episode Guest: Dr. Mikael Simons Privacy Policy

Just a couple of weeks ago, 1,800 scientists, clinicians, postdoctoral fellows, and medical residents gathered in West Palm Beach, Florida, for the Americas Committee for Treatment and Research in Multiple Sclerosis annual meeting, better known as the ACTRIMS Forum. Dr. Daniel Reich is a neurologist and neuroradiologist. He is the Director of the Translational Neuroradiology Section at the NIH National Institute of Neurological Disorders and Stroke. In his clinical practice, Dr. Reich cares for people living with MS and other neurological diseases, and he leads several clinical trials focused on multiple sclerosis. At the ACTRIMS Forum, we talked with Dr. Reich about myelin repair, how improvements in imaging have impacted diagnosing and treating MS, and what he sees in MS research today that has him excited. We have a lot to talk about! Are you ready for RealTalk MS??! SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/actrims05 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Bonus Episode Guest: Dr. Daniel Reich Privacy Policy

Just a couple of weeks ago, 1,800 scientists, clinicians, postdoctoral fellows, and medical residents gathered in West Palm Beach, Florida, for the Americas Committee for Treatment and Research in Multiple Sclerosis annual meeting, better known as the ACTRIMS Forum. Dr. Christina Azevedo is an Associate Professor of Neurology at the University of Southern California. At the ACTRIMS Forum, we talked with Dr. Azevedo about updates to the McDonald criteria, which are the criteria used to diagnose MS, and the benefits of getting an early MS diagnosis. We have a lot to talk about! Are you ready for RealTalk MS??! SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/actrims04 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Bonus Episode Guest: Dr. Christina Azevedo Privacy Policy

Just a couple of weeks ago, 1,800 scientists, clinicians, postdoctoral fellows, and medical residents gathered in West Palm Beach, Florida, for the Americas Committee for Treatment and Research in Multiple Sclerosis annual meeting, better known as the ACTRIMS Forum. Dr. Peter Calabresi is the Director of the Division of Neuroimmunology and the Director of the Multiple Sclerosis Center at Johns Hopkins Medicine, focusing on the diagnosis and management of MS. He is the principal investigator on several clinical trials and oversees research projects focused on creating new anti-inflammatory and neuroprotective therapies for MS. At the ACTRIMS Forum, we talked with Dr. Calabresi about updates to the criteria used to diagnose MS, the importance and benefit of identifying biomarkers for MS, and what he sees in MS research today that has him excited. We have a lot to talk about! Are you ready for RealTalk MS??! SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/actrims03 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Bonus Episode Guest: Dr. Peter Calabresi Privacy Policy

It's MS Awareness Week, and the National MS Society is asking everyone in the MS community to tell MS exactly what they think of it. We're kicking off MS Awareness Week by introducing you to two difference-makers in the MS community who have each found their own way of talking back to MS.   Case Jernigan is an experimental animator, narrative gamemaker, and educator. His short animated documentary, Noggin, is currently making the rounds of the film festival circuit, raising awareness of how Case reacted and responded to his early symptoms of MS. Suni Conway is an MS activist who has lived with MS for nearly 13 years. Suni uses her social media platform to raise awareness about MS diagnosis and treatment, and the need for healthcare reform.  Be sure to follow RealTalk MS all week long, as we celebrate MS Awareness Week with bonus episodes featuring conversations with leading MS experts from the 2025 ACTRIMS Forum! We have a lot to talk about! Are you ready for RealTalk MS??!   This Week: It's MS Awareness Week!  :22 Case Jernigan explains how his short animated documentary, Noggin, reflects the early parts of his MS journey  1:02 Suni Conway discusses the motivation behind her social media efforts and why advocacy is so important     12:05 Share this episode  35:52 Don't miss RealTalk MS bonus episodes all week long during MS Awareness Week!  36:12 Have you downloaded the free RealTalk MS app?  36:32 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/393 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS VIDEO: Noggin https://vimeo.com/casejernigan/noggin Suni Conway on Instagram https://www.instagram.com/sunisideupproject Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 393 Guests: Case Jernigan and Suni Conway Privacy Policy

Just a couple of weeks ago, 1,800 scientists, clinicians, postdoctoral fellows, and medical residents gathered in West Palm Beach, Florida, for the Americas Committee for Treatment and Research in Multiple Sclerosis annual meeting, better known as the ACTRIMS Forum. Dr. Darin Okuda is the Director of the Multiple Sclerosis and Neuroimmunology Imaging Program, the Director of  Neuroinnovation, and the Deputy Director of the Multiple Sclerosis Program and Clinical Center for Multiple Sclerosis at University of Texas Southwestern Medical Center. At the ACTRIMS Forum, we talked with Dr. Okuda about the impact of artificial intelligence on MS care, how to go about preventing MS, and a frightening case study of what went wrong with an MS patient's generic disease-modifying therapy.  We have a lot to talk about! Are you ready for RealTalk MS??! SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/actrims01 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Bonus Episode Guest: Dr. Darin Okuda Privacy Policy

Just a couple of weeks ago, 1,800 scientists, clinicians, postdoctoral fellows, and medical residents gathered in West Palm Beach, Florida, for the Americas Committee for Treatment and Research in Multiple Sclerosis annual meeting, better known as the ACTRIMS Forum. Dr. Nara Michaelson is a Multiple Sclerosis Fellow at Harvard's Massachusetts General Hospital. We first talked with Dr. Michaelson last summer when her article, The Unraveling, was published in the journal, Neurology.  At the ACTRIMS Forum, we talked with Dr. Michaelson about how she uses arts therapy with her patients, and how lessons learned studying piano when she was 8 years old continue to serve her today in her work as an MS specialist.  We have a lot to talk about! Are you ready for RealTalk MS??! SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/actrims02 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Bonus Episode Guest: Dr. Darin Okuda Privacy Policy

Last week, 1,800 scientists, clinicians, postdoctoral fellows, and medical residents arrived in West Palm Beach, Florida, for the Americas Committee for Treatment and Research in Multiple Sclerosis annual meeting, better known as the ACTRIMS Forum. I'm kicking off our coverage of this important conference by sharing two of the conversations I had at ACTRIMS 2025. First, I talked with Dr. Lilyana Amezcua about the Alliance for Research in Hispanic Multiple Sclerosis, and her just-published paper, The Impact of Person-Centered Social Determinants and Neighborhood Deprivation Associated with Disability in Hispanic People with Multiple Sclerosis. I also talked with Dr. John Corboy about aging and MS, and what he learned as the Principal Investigator of DISCO-MS, the largest clinical trial to focus on the question of whether it makes sense for someone over the age of 55 or 60 to discontinue their disease-modifying therapy.  We have a lot to talk about! Are you ready for RealTalk MS??! This Week: From the 2025 ACTRIMS Forum  :22 Dr. Lilyana Amezcua discusses the Alliance For Research in Hispanic Multiple Sclerosis, and her paper focused on the impact of person-centered social determinants and neighborhood deprivation associated with disability in Hispanic people with multiple sclerosis  2:06 Dr. John Corboy discusses aging and MS, and what he learned as the Principal Investigator of DISCO-MS, the largest clinical trial to focus on the question of whether it makes sense for someone over the age of 55 or 60 to discontinue their disease-modifying therapy.   12:05 Share this episode  21:37 Next Week: Look for special episodes of the podcast with lots more interviews from the ACTRIMS Forum, featuring some of the leading MS experts in the world  21:57 Have you downloaded the free RealTalk MS app?  22:10 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/392 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS RESEARCH PARTICIPATION OPPORTUNITY: The Global PROMS Initiative eHealth Survey https://proms-initiative.org Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 392 Guests: Dr. Lilyana Amezcua and Dr. John Corboy Privacy Policy

In this episode, Scott Davert explores the different ways to access the Home Screen on iPhones without a Home Button. With the launch of the iPhone 16e, Apple has fully transitioned to a buttonless design, changing how users interact with their devices. For those accustomed to the tactile feedback of the Home Button, this shift may feel challenging. However, several alternative methods can replicate its functionality.1. Using the Default Gesture:To return to the Home Screen without a physical button:Place a finger at the bottom center of the screen.Quickly swipe upward until you feel a slight vibration or hear a "pop" sound.Release your finger to navigate to the Home Screen.Tip: Using the charging port as a reference point can help with finger placement. Adding a small tactile marker, such as a bump dot, on your case near the swipe area can also provide a reliable guide.2. Customizing VoiceOver Gestures:VoiceOver users can assign the Home function to a different gesture for easier navigation:Assigning Home to a Two-Finger Swipe Right:Open Settings > Accessibility > VoiceOver > Commands > Touch Gestures.Choose a gesture, such as a two-finger swipe right.Under the "System" section, select "Home".If the gesture is already assigned, iOS will notify you. Confirm the reassignment by selecting "Assign".Note: The two-finger swipe right is typically used for grouped navigation, so choose another gesture if this conflicts with your existing setup.3. Enabling Back Tap:Back Tap allows users to activate specific functions by tapping the back of their iPhone:Setting Up Back Tap for Home Screen Access:Go to Settings > Accessibility > Touch > Back Tap.Toggle "Back Tap" on.Choose "Triple Tap".From the options, select "Home".Observation: If you use a thick phone case, Back Tap may not work as effectively. Adjust your tapping technique or consider using a thinner case if needed.4. Using the Action Button with Siri Shortcuts:On certain iPhone models with an Action Button, you can program it to bring you to the Home Screen using a Siri Shortcut:Configuring the Action Button for Home:Download the shortcut, courtesy of AppleVis' very own AnonyMouse. on a compatible iPhone.If the shortcut doesn't run automatically, tap "Add Shortcut" to enable it.Navigate to Settings > Action Button.Select "Shortcut" from the menu.Choose "Go to Home Screen" from the list of shortcuts.Now, pressing and holding the Action Button will return you to the Home Screen.Reminder: To maintain security, only download shortcuts from reputable sources.By utilizing these methods, users can easily adjust to Apple's buttonless design, ensuring a smooth and intuitive experience on modern iPhones.If you'd like to read this in a written guide, you can find it here: Finding Your Way Home in a (Home) Buttonless World: Using an iOS Device Without a Home ButtonTranscript…

Today's show: Jason and Lon break down the latest trends shaping AI training, the evolving job market, and the shifting landscape of social media. A tribute to Steve Jobs on what would have been his 70th birthday explores his lasting impact, Apple's massive $500 billion AI investment, and the future of US manufacturing. The conversation dives into Outlier's role in AI training data, its effects on journalism, and broader job market implications. Jason also shares insights on autonomous vehicles, Apple's AI strategy, and the latest in crypto—covering meme coins, regulatory battles, and the state of angel investing. Plus, a look at Oscar season and the cultural moments making waves.*Timestamps:(0:00) Jason and Lon kick off the show!(2:59) TikTok discussion and Steve Jobs' 70th birthday tribute(4:36) Jason's history with Steve Jobs and impact of blogging(8:56) Jason's interaction with Steve Jobs about podcast monetization(10:13) Squarespace. Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(11:27) Steve Jobs' legacy and Apple's innovation(14:12) Apple's $500 billion investment in AI and TSMC chip manufacturing(20:08) Vanta. Get $1000 off your SOC 2 at https://www.vanta.com/twist(21:18) Geopolitical implications of Apple's US manufacturing investments(24:06) Outlier's role in AI training data and legal risks(27:02) Journalists in AI training and job market implications(30:40) Vapi. Go to https://www.vapi.ai and use code Twist200 to get $200 in credits(32:39) Outlier's AI training recruitment and global reach(34:14) AI's future in various industries(36:53) Experiences with autonomous vehicles and Waymo(37:23) Hot-swappable LLMs and Apple's AI integrations(41:03) Commercial implications of AI deals for Apple(43:08) Public access to podcast docket and meme coins discussion(47:03) Milei's meme coin and libertarian views on crypto(52:15) Crypto trader's tragic incident and dangers of investing on margin(58:19) Jason's gambling habits and future of crypto regulation(1:01:05) Angel investing and Oscar season discussion*Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcp*Follow Lon:X: https://x.com/LonsLinkedIn: https://www.linkedin.com/in/lonharris*Follow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanis*Thank you to our partners:(10:13) Squarespace. Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(20:08) Vanta. Get $1000 off your SOC 2 at https://www.vanta.com/twist(30:40) Vapi. Go to https://www.vapi.ai and use code Twist200 to get $200 in credits*Great TWIST interviews: Will Guidara,Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta,Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland*Check out Jason's suite of newsletters: https://substack.com/@calacanis*Follow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com*Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

MS can limit your ability to get around and do the things you like to do. And when that happens, the right mobility device can be a game-changer when it comes to staying safe, staying active, and improving your quality of life. This week, Dr. Evan Cohen joins me to discuss how to know when it's time to consider a mobility device, and how to choose the right mobility device for you. We're also presenting findings from two separate studies that shed significant light on how the gut microbiome interacts with the brain and how its composition varies among individuals with MS. We'll tell you what happened when a research team gave a multiple-choice "test" measuring MS expertise to neurologists and neurology residents and then gave the same test to the leading artificial intelligence platforms. And we'll share an opportunity for you to participate in MS research by taking the PROMS Initiative's eHealth survey. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Choosing the right mobility device  :22 Differences in the gut microbiome of people with MS  1:28 Evidence shows the vagus nerve is the connection between the gut and the brain  3:53 Who won the "MS expertise" showdown between neurologists and AI?  6:18 Your opportunity to participate in MS research by taking the PROMS initiative survey  8:31 Dr. Evan Cohen shares everything you need to know about choosing a mobility device  10:27 Share this episode  30:57 Have you downloaded the free RealTalk MS app?  31:15 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/391 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS STUDY: Alterations in Gut Microbiome-Host Relationships After Immune Perturbation in Patients with Multiple Sclerosis  https://neurology.org/doi/10.1212/NXI.0000000000200355 STUDY: Select Microbial Metabolites In the Small Intestinal Lumen Regulates Vagal Activity Via Receptor-Mediated Signaling https://cell.com/iscience/fulltext/S2589-0042(24)02926-2 STUDY: Artificial Intelligence Versus Neurologists: A Comparative Study on Multiple Sclerosis Expertise https://sciencedirect.com/science/article/abs/pii/S030384672500068X RESEARCH PARTICIPATION OPPORTUNITY: The Global PROMS Initiative eHealth Survey https://proms-initiative.org Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 391 Guest: Dr. Evan Cohen Privacy Policy

More than half of the people living with MS live with pain. And, too often, the distraction and discomfort of MS-related pain can stop you from fully engaging in every aspect of your life. Dr. Bianca Weinstock-Guttman joins me to discuss treatment options for managing MS pain. Dr. Weinstock-Guttman is a neurologist and professor of neurology at the Jacobs School of Medicine and Biomedical Sciences at the University of Buffalo, where she also serves as the Director of the Jacobs Multiple Sclerosis Center for Treatment and Research. We're also taking a moment to respond to all your questions and concerns about the state of healthcare policy and administration in the U.S. federal government. MS experts in Australia and New Zealand have released recommendations for MS care in those countries. We're sharing all the details.  We'll tell you about the National MS Society's initiative designed to improve access to MS care in rural communities in the U.S. And we'll share the details of a study that shows that, together, obesity and smoking worsen MS symptoms faster. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Managing MS pain  :22 Responding to your concerns about healthcare in the U.S.  :57 Recommendations published for treating MS in Australia and New Zealand  7:16 National MS Society has launched an initiative designed to improve access to MS care in rural communities in the United States  9:09 Together, smoking and obesity worsen MS physical and cognitive symptoms faster  12:46 Dr. Bianca Weinstock-Guttman shares treatment options for managing MS pain  14:14 Share this episode  29:19 Have you downloaded the free RealTalk MS app?  29:38 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/390 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS Consensus Recommendations on Multiple Sclerosis Management in Australia and New Zealand https://mja.com.au/journal/2025/222/7/consensus-recommendations-multiple-sclerosis-management-australia-and-new STUDY: Smoking and Obesity Interact to Adversely Affect Disease Progression and Cognitive Performance in Multiple Sclerosis https://onlinelibrary.wiley.com/doi/10.1111/ene.70058 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 390 Guest: Dr. Bianca Weinstock-Guttman Privacy Policy

Living your best life with MS means learning to overcome the stigma of having a disability, successfully navigating social relationships, and learning how to ask for and accept help. Joining me to share their perspectives and their experiences in overcoming some of these social obstacles are Denise Schnieders, who was diagnosed with MS just about a year ago, and Fox Rigney, who's been living with MS since 2012. We're also applauding a forward-thinking caregiver leave benefit that's just been announced by EMD Serono. We're sharing results of a study that show MS lesions dynamically change over time and explains why those changes aren't apparent on MRI scans.  We'll tell you about an AI-powered drug repurposing platform that has identified a potential treatment for MS. We'll also share an announcement from the CEO of Google's artificial intelligence company,  DeepMind, that we will see pharmaceutical drugs developed by artificial intelligence in clinical trials by the end of this year. And we'll share the details of a Phase 2 clinical trial that you may qualify to participate in. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Overcoming the stigma of disability, navigating social situations, and how to ask for and receive help  :22 EMD Serono implements caregiver leave benefit (And we're applauding!)  1:04 Imaging study reveals that T-2 lesions expand and contract "invisibly"  3:16 Has an AI drug repurposing platform discovered a new treatment for MS?  6:22 We will see pharmaceutical drugs developed by artificial intelligence in clinical trials this year  8:06 Your opportunity to participate in MS resesarch  10:54 Denise Schnieders and Fox Rigney discuss overcoming the stigma of MS  14:04 Share this episode  32:46 Have you downloaded the free RealTalk MS app?  33:06 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/389 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS Dynamic Expansion and Contraction of Multiple Sclerosis T-2 Weighted Hyperintense Lesions Are Present Below the Threshold of Visual Perception https://www.ajnr.org/content/early/2025/01/16/ajnr.A8453 Contact Information for Obexelimab Phase 2 Clinical Trial Phone: (833) 269-4696 Email: clinicaltrialsinfo@zenasbio.com Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 389 Guests: Denise Schnieders and Fox Rigney Privacy Policy

When we talk about myelin damage, most of us typically think of the brain. After all, that myelin is located in your central nervous system. But the inflammation that causes myelin damage may be triggered by activity that's taking place well south of your central nervous system, in your gut microbiome, the colony of trillions of bacteria and microorganisms that live in your intestines.  Dr. Ashutosh Mangalam joins me to help us understand what this gut-brain connection is all about, how that connection impacts MS, and what you can do to change the makeup of your gut microbiome. Dr. Mangalam is an Associate Professor of Pathology at the Carver College of Medicine at the University of Iowa, where his research is focused on studying the gut microbiome and the immune system in multiple sclerosis. We're also talking about the newly published guidance from the European Committee for Treatment and Research in MS and the European Society for Blood and Marrow Transplantation, recommending autologous hematopoietic stem cell transplantation (aHSCT) for treating some cases of relapsing-remitting MS. We'll tell you about an experimental drug that may resolve MS-related vision issues through remyelination.  And we'll introduce you to this year's winner of the Barancik Prize for Innovation in MS Research. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: The gut-brain connection (and what it means if you're liviing with MS)  :22 The European Committee for Treatment and Research in MS and the European Society for Blood and Marrow Transplantation issue a recommendation for stem cell therapy to treat relapsing-remitting MS  1:35 Researchers develop a drug that may resolve MS-related vision issues through remyelination  4:44 National MS Society names this year's winner of the Barancik Prize for Innovation in MS Research  7:23 Dr. Ashutosh Mangalam explains how (and why) the brain-gut connection impacts MS    11:14 Share this episode  35:38 Have you downloaded the free RealTalk MS app?  35:58 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/388 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS Autologous Hematopoietic Stem Cell Transplantation for Treatment of Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorder -- Recommendations from ECTRIMS and EBMT https://www.nature.com/articles/s41582-024-01050-x National MS Society Releases Recommendations for aHSCT-Bone Marrow Transplant for MS https://nationalmssociety.org/news-and-magazine/news/national-ms-society-releases-recommendations STUDY: Incomplete Remyelination Via Therapeutically Enhanced Oligodendrogenesis Is Sufficient to Recover Visual Cortical Functionhttps://www.nature.com/articles/s41467-025-56092-6 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 388 Guest: Dr. Ashutosh Mangalam Privacy Policy

The TEAAMS study examines the effects of a remotely delivered, racially-tailored exercise training program among African-Americans with MS, who are living in low-income areas of the Southeastern United States, which is a part of the country that doesn't have many primary care or MS clinics that provide full exercise and rehabilitation services for patients with MS. Ashli, who lives with MS and has completed the TEAAMS program, and Victoria, a behavioral coach who has worked with several study participants, join me this week to share their experiences in the study. We're also talking about a new Phase1/2 clinical trial for another investigative CAR-T therapy. (And we'll explain what a Phase 1/2 trial is) We'll tell you about TG Therapeutics' plans for Briumvi, as well as their investigative CAR-T therapy. We'll tell you about the Phase 2 clinical trial for Contineum Therapeutics' oral remyelination therapy. We'll share the details of a study that shows ballroom dancing delivers both physical and psychological benefits to people with MS.  We'll share some potentially good news about managing MS-related fatigue. And we'll give you a new opportunity to participate in MS research. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Inside the TEAAMS study  :22 Cabaletta Bio announces Phase 1/2 trial for CAR-T therapy  1:45 TG Therapeutics will develop an injectable formulation for Briumvi  5:45 Contineum Therapeutics completes recruitment for Phase 2 trial for an oral remyelination therapy  7:52 Study shows that ballroom dancing delivers physical and psychological benefits for people with MS  9:05 Study shows that Elevida, an online German fatigue intervention, significantly reduces MS-related fatigue   11:32 Ashli and Victoria share their experience in the TEAAMS study    15:37 Share this episode  32:57 Have you downloaded the free RealTalk MS app?  33:17 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/387 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS STUDY: Ballroom Dancing for People with Multiple Sclerosis: Perceptions of the Experience https://meridian.allenpress.com/ijmsc/article/26/Q4/355/504470/Ballroom-Dancing-for-People-With-Multiple PARTICIPATE IN MS RESEARCH: Targeted Exercise for African-Americans with Multiple Sclerosis (TEAAMS) https://projectteaams.ahs.uic.edu/ PARTICIPATE IN MS RESEARCH: Confirmatory Trial for Alleviating Fatigue in MS (CAFE-MS)https://cafems.iconquerms.org/ Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 387 Guests: Ashli and Victoria Privacy Policy

MS symptoms can worsen, and relapses can occur. And when that happens, how do you know whether you require immediate medical care? When is it time to go to the hospital? Dr. Kalina Sanders joins me to talk about when it's time to seek immediate medical care for MS. Dr. Sanders is a board-certified neurologist who specializes in multiple sclerosis and spasticity management at Baptist Health in Jacksonville Beach, Florida. We're also talking about MS care in the United Arab Emirates with Professor Bassem Yamout, the President of the Middle East North Africa Committee for Treatment and Research in Multiple Sclerosis. We'll explain why Bayer's new MRI contrast agent is good news for people with MS. We'll tell you about a new Federal Trade Commission report that calls out Pharmacy Benefit Managers for inflating the price of generic specialty drugs by thousands of percent. We'll share the details of a study that shows the profound impact of menopause on MS. And we're sharing two different opportunities for you to participate in MS research. We have a lot to talk about! Are you ready for RealTalk MS??! A word about Facebook posts  :22 This Week: Worsening symptoms? Relapse? When is it time to go to the Emergency Room?  1:46 FTC reports Pharmacy Benefit Managers have marked up generic specialty drugs 1000s of percent  2:20 Bayer's new MRI contrast agent contains 60% less gadolinium  4:57 Professor Bassem Yamout discusses MS in the United Arab Emirates  6:48 Study reveals menopause significantly increases the speed of disability worsening and brain cell damage in women with MS  15:08 Two opportunities for you to participate in MS research  17:38 Dr. Kalina Sanders explains when it's time to seek immediate medical care for MS     19:54 Share this episode  31:42 Have you downloaded the free RealTalk MS app?  32:02 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/386 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS Federal Trade Commission Interim Report on Pharmacy Benefit Managers and Specialty Generic Drugs https://www.ftc.gov/reports/specialty-generic-drugs-growing-profit-center-vertically-integrated-pharmacy-benefit-managers Bayer Announces MRI Contrast Agent Gadoquatrane Meets Primary and Main Secondary Endpoints in Pivotal Phase III Studies https://www.businesswire.com/news/home/20250109869429/en/Bayers-investigational-MRI-contrast-agent-gadoquatrane-meets-primary-and-main-secondary-endpoints-in-pivotal-Phase-III-studies STUDY: Association of Menopause with Functional Outcomes and Disease Biomarkers in Women with Multiple Sclerosis https://www.neurology.org/doi/10.1212/WNL.0000000000210228 PARTICIPATE IN MS RESEARCH: Psychometric Properties of Sexual Difficulties Scales in People Living with Multiple Sclerosis https://qualtrics.kcl.ac.uk/jfe/form/SV_br1fVoYGqXnLooK PARTICIPATE IN MS RESEARCH: Efficacy and Safety Study of Frexalimab in Adults with Nonrelapsing Secondary Progressive Multiple Sclerosishttps://www.sanofistudies.com/SR0A/ Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 386 Guests: Professor Bassem Yamout, Dr. Kalina Sanders Privacy Policy

The new year brings with it several significant benefits for many people affected by MS. We're reviewing how the nearly 400,000 people with MS who rely on Medicare for their health insurance will save thousands of dollars, how people with MS who currently have medical debt will see a big improvement on their credit report, and how people who fly with their mobility device will see major improvements in how the airlines treat them. We're also talking with Craig Bianco about his experience as a member of the Care Partner Advisory Board creating the MS Care Partner Connection web portal. And we'll tell you about the Phase 1 clinical trial for the Epstein-Barr Virus vaccine that's getting underway. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Where to get support if you have MS and you're a victim of the Southern California fires   :22 Here's where and how 2025 is delivering new and improved benefits for many people with MS  2:06 Department of Transportation adopts new rules to improve flying for people with disabilities  10:26 Modex Therapeutics, in collaboration with Merck, announces Phase 1 clinical trial for Epstein-Barr Virus vaccine  14:03 Craig Bianco talks about his experience as a member of the Care Partner Advisory Board creating the MS Care Partner Connection web portal     17:26 Share this episode  29:12 Have you downloaded the free RealTalk MS app?  29:32 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/385 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS MS Care Partner Connection https://mscarepartnerconnection.com Find Out How You Can Become an MS Activist https://nationalmssociety.org/advocacy RealTalk MS Episode 302: De-Stressing Air Travel if You're Living with MS with Dr. Scott Crawford https://realtalkms.com/302 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 385 Guest: Craig Bianco Privacy Policy

There are genetic risks associated with MS, there are demographic risks of experiencing a more severe disease course, and there are also behavioral and lifestyle risks that will increase the chance that someone will be diagnosed with MS. Joining me today to discuss behavioral and lifestyle MS risk factors and how they can be mitigated are Doctor Jared Bruce and Dr. Amanda Bruce. Dr. Jared Bruce is a neuropsychologist and the director of psychiatric research at the University of Missouri-Kansas City School of Medicine. Dr. Amanda Bruce is a clinical psychologist and an assistant professor in the Department of Behavioral Pediatrics at the University of Kansas Medical Center. We're also reviewing the details of the Inflation Reduction Act, which means, beginning in 2025, significantly lower out-of-pocket costs for prescription medications for the quarter-million people with MS who are on Medicare.  We'll tell you about study results for a novel drug that was effective in remyelination and restoring lost function to mice with the mouse model of MS. We'll share the details of a study that shows how specific comorbidities affect specific MS outcomes. We'll review results of a study that shows men with MS who start a high-efficacy disease-modifying therapy experience fewer relapses. And we'll tell you how an artificial intelligence chatbot soundly beat human experts in predicting the results of neuroscience studies. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Behavioral and Lifestyle risk factors for MS (and how to mitigate them)   :22 It's 2025, and that means significant out-of-pocket savings on prescription medications for people with MS on Medicare  1:20 Novel drug shows effectiveness in remyelination and restoring function in mouse model of MS  3:26 Study shows how specific comorbidities affect specific MS outcomes  5:17 Study shows men on high-efficacy disease-modifying therapies experience fewer MS relapses  8:46 Study shows AI beats human experts in predicting results of neuroscience studies  12:22 Dr. Jared Bruce and Dr. Amanda Bruce discuss behavioral and lifestyle MS risk factors   16:43 Share this episode  32:13 Have you downloaded the free RealTalk MS app?  32:33 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/384 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS STUDY: Selective Retinoid X Receptor Agonism Promotes Functional Recovery and Myelin Repair in Experimental Autoimmune Encephalomyelitis https://actaneurocomms.biomedcentral.com/articles/10.1186/s40478-024-01904-x STUDY: Comorbidities and Their Association with Outcomes In the Multiple Sclerosis Population: A Rapid Review https://msard-journal.com/article/S2211-0348(24)00519-4/fulltext STUDY EXPLAINED (Plain English): Comorbidities and Their Association with Outcomes In the Multiple Sclerosis Population: A Rapid Review https://tremlettsmsresearchexplained.wordpress.com/2024/10/29/comorbidities-and-their-association-with-outcomes-in-the-multiple-sclerosis-population-a-rapid-review-explained STUDY: Comparative Effectiveness of High-Efficacy and Moderate-Efficacy Disease-Modifying Agents in Reducing the Annualized Relapse Rates Among Multiple Sclerosis Patients in the United States https://sciencedirect.com/science/article/abs/pii/S0091743524003359 STUDY: Large Language Models Surpass Human Experts in Predicting Neuroscience Results https://nature.com/articles/s41562-024-02046-9 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 384 Guests: Dr. Jared Bruce and Dr. Amanda Bruce Privacy Policy

One of the most important MS research events every year is the annual European Committee for Treatment and Research in MS Scientific Congress, usually referred to by its acronym, ECTRIMS.    You've made our podcast episode that followed ECTRIMS the most downloaded episode of the year. So, this week, I'm revisiting the two conversations that I had immediately after the ECTRIMS conference ended. In what has become an annual tradition, it's my privilege to sit down with the National MS Society's Executive Vice-President of Research, Dr. Bruce Bebo, just minutes after the conclusion of ECTRIMS to get his first impressions of the news and presentations that caught his eye.   This year, I also wanted to bring you the perspective of someone who's living with MS, who attended ECTRIMS for the very first time.  So, less than an hour after the conference concluded, I had a conversation with Kristine Werner Ozug. (Full disclosure, Kristine is a member of the RealTalk MS team.) We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Revisiting ECTRIMS 2024   :22 Dr. Bruce Bebo shares the announcements and presentations that caught his eye at ECTRIMS  1:59 Kristine Werner Ozug shares a patient's perspective on attending the largest MS research conference in the world  14:07 Share this episode  26:54 Have you downloaded the free RealTalk MS app?  27:14 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/383 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS at ECTRIMS on YouTube https://www.youtube.com/playlist?list=PLATxgj1uHpxPOTklQKDkASWTEBoHXVGH1 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 383 Guests: Dr. Bruce Bebo and Kristine Werner Ozug Privacy Policy

The holiday season provides me with an opportunity to indulge in what's become a RealTalk MS tradition. I reserve the last two episodes of the year to revisit the most compelling and important conversations that I've had over the past year. This week, I'm revisiting two conversations I had with two experts on MS and women's health issues. MS affects women almost 3 times more frequently than it affects men, which should make understanding how MS might impact other women's health issues a priority. Unfortunately, that hasn't really been the case. The good news is we're seeing that situation change and you can expect to hear much more about MS and women's health in the coming year.    This brings me to two conversations that I had this past year when I talked with Dr. Rhonda Voskuhl and Dr. Anna Shah.    Dr. Shah is an Associate Professor of Neurology and Associate Clinic Director of Outpatient Neurology at the University of Colorado School of Medicine.   Dr. Voskuhl is the Director of the UCLA Multiple Sclerosis Program, she holds the Jack H. Skirball Chair in MS, and Dr. Voskuhl also serves as Faculty Neurologist of the UCLA Comprehensive Menopause Care Program. We have a lot to talk about! Are you ready for RealTalk MS??! Happy Holidays!  :22 This Week: Revisiting our deep dive into women's health and MS   :44 Dr. Rhonda Voskuhl discusses her research looking at why MS affects men and women differently  2:34 Dr. Anna Shah discusses how MS can affect women's health issues and how those health issues can affect MS  13:30 Share this episode  32:18 Have you downloaded the free RealTalk MS app?  32:38 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/382 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS at ECTRIMS on YouTube https://www.youtube.com/playlist?list=PLATxgj1uHpxPOTklQKDkASWTEBoHXVGH1 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 382 Guests: Dr. Anna Shah, Dr. Rhonda Voskuhl Privacy Policy

There's an alarming shortage of neurologists in the United States. That shortage makes it hard to be seen by a neurologist and, in some regions of the U.S., you may not even find an MS specialist without having to travel hundreds of miles. The good news is now there's an app for that! Joining me to talk about how an app called BeCare is already changing the game when it comes to MS care is the Chief Medical Officer of BeCareLink, Dr. Charisse Litchman. The FDA has designated Tolebrutinib as a Breakthrough Therapy for the treatment of adults with non-relapsing secondary progressive MS. We're sharing the details. We'll tell you where you can participate in a phase 2 clinical trial that's designed to test the efficacy of Foralumab, an investigational disease-modifying therapy formulated as a nasal spray, among adults with non-relapsing secondary progressive MS. We'll share the details of a report that provides some frustrating data about out-of-pocket costs for MS prescription medications. Dr. Alicyn Magruder reviews the risks and benefits of using off-label medications to manage MS. And we'll share the results of a study that focused on how socioeconomic status impacts disease severity among kids and teens living with MS. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: An app that can tell you if your MS is worsening   :22 FDA awards Tolebrutinib Breakthrough Therapy designation  1:04 Phase 2 clinical trial for Foralumab adds 6 additional sites  3:13 Study compares out-of-pocket costs of MS DMTs with meds for other neurologic conditions  5:55 Dr. Alicyn Magruder discusses using off-label medications to manage MS  9:51 Study analyzes the impact of socioeconomic status on disease severity in pediatric-onset MS  15:27 Dr. Charisse Lichtman explains how the BeCare MS app is changing the game and providing an important bridge to better MS care   19:52 Share this episode  30:53 Have you downloaded the free RealTalk MS app?  31:13 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/381 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.msif.org/webcast-clinical-trials CLINICAL TRIAL: A Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients https://clinicaltrials.gov/study/NCT06292923 STUDY: Costs Are Still On the Rise for Commonly Prescribed Branded Neurologic Medications https://neurology.org/doi/10.1212/WNL.0000000000210029 STUDY: Association of Social Determinants of Health with Brain MRI Outcomes in Individuals with Pediatric Onset Multiple Sclerosis https://neurology.org/doi/10.1212/WNL.0000000000210140 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 381 Guests: Dr. Alicyn Magruder, Dr. Charisse Litchman Privacy Policy

If you're living with MS, you've probably already learned that hot weather, hot baths, or anything that causes your body temperature to increase can quickly cause your symptoms to worsen. But winter can also be a challenging time. Less daylight, frigid temperatures, ice, and snow can all have an impact on MS. Dr. Lisa Doggett returns to the podcast with tips and strategies for enjoying winter while staying healthy, safe, and warm.  We'll also remind you that the International Progressive MS Alliance global webcast is happening tomorrow -- Dec. 11th! And we'll share the details you'll need to sign up. We'll tell you about study results from Sweden that show that experiencing serious COVID-19 makes it twice as likely that someone will develop MS. (And we'll tell you why those study results aren't as scary as they may sound!) We're sharing research that has uncovered evidence of nerve damage in the central nervous system up to 9 years before someone experiences MS symptoms. We'll tell you about a team of biomedical engineers who are creating a tiny implantable device that will warn you if your MS is worsening or if you're heading for a relapse. And if you're over 55, you're living with MS, and you have 15 minutes to spare, we'll tell you about an online survey that we hope you'll decide to participate in. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Winning against winter when you're living with MS   :22 Don't miss the International Progressive MS Alliance global webcast on Dec. 11  1:46 A study shows that serious COVID-19 doubles the likelihood that someone will develop MS  2:42 Research reveals that nerve damage can occur in the central nervous system up to 9 years before you can experience any symptoms of MS  6:13 Imagine a tiny device implanted in your arm that can alert you if your MS is worsening or you're headed for a relapse   8:48 If you're 55 years old or older and you've been diagnosed with MS, there's a survey just for you  10:56 Dr. Lisa Doggett shares tips and strategies for thriving in cold weather when you're living with MS  12:29 Share this episode  26:14 Have you downloaded the free RealTalk MS app?  26:33 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/380 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com REGISTER FOR THE WEBCAST: What We're Learning from Clinical Trials https://www.msif.org/webcast-clinical-trials STUDY: SARS-CoV-2 Infection and Risk of Subsequent Demyelinating Diseases: National Register-Based Cohort Study https://academic.oup.com/braincomms/article/6/6/fcae406/7909395 STUDY: Temporal Dynamics of Plasma Neurofilament Light In Blood Donors with Preclinical Multiple Sclerosis https://neurology.org/doi/10.1212/NXI.0000000000200335 SURVEY: If you are 55 years old or older and living with MS, please complete https://illinois.qualtrics.com/jfe/form/SV_5oM7xmdpdSphTiC Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 380 Guests: Dr. Lisa Doggett Privacy Policy

Disease-modifying therapies work, and, as a result, people with MS are living longer. With half the MS population over the age of 55, it's never been more urgent to understand how the process of aging impacts MS and how MS impacts the process of aging. In this special episode of RealTalk MS, Dr. Leorah Freeman discusses the many factors associated with aging with MS. This special episode of RealTalk MS is sponsored by Viatris. SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/V202 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode V202 Guests: Dr. Leorah Freeman Privacy Policy

Apple @ Work is exclusively brought to you by Mosyle, the only Apple Unified Platform. Mosyle is the only solution that integrates in a single professional-grade platform all the solutions necessary to seamlessly and automatically deploy, manage & protect Apple devices at work. Over 45,000 organizations trust Mosyle to make millions of Apple devices work-ready with no effort and at an affordable cost. Request your EXTENDED TRIAL today and understand why Mosyle is everything you need to work with Apple. In this episode of Apple @ Work, I talk with Mike McNeil from Fleet about its recent upgrade to iPhone and iPad device management. Links Popular Apple TV digital signage tool launches new 2.0 version Connect with Bradley Twitter LinkedIn Listen and subscribe Apple Podcasts Overcast Spotify Pocket Casts Castro RSS Listen to Past Episodes

More effective treatments and even cures for MS can only happen as a result of clinical research. And clinical research can only happen when people living with MS choose to become research participants. But what are the pros and cons that you should consider when you're thinking about participating in MS research? The National MS Society's Associate Vice President of Research, Dr. Kathy Zackowski, returns to the podcast to discuss the risks and benefits of participating in clinical research. We're also joined by Mimi Brown, who lives with primary progressive MS. Mimi will share her experiences as a participant in several MS research studies. We'll also remember Professor Giancarlo Comi, a true giant in the MS research community who passed away last week. We'll discuss the updated Brain Health -- Time Matters report. We'll tell you about a research collaboration between the National MS Society, Breakthrough T1D (formerly the Juvenile Diabetes Research Foundation), and the Lupus Research Alliance. And we're sharing the details about the International Progressive MS Alliance's upcoming global webcast. We have a lot to talk about! Are you ready for RealTalk MS??! Remembering Professor Giancarlo Comi  :22 This Week: Participating in MS research   3:28 Experts release the Brain Health -- Time Matters report  4:10 The National MS Society teams up with Breakthrough T1D and the Lupus Research Alliance to fund research in common mechanisms that drive autoimmunity  6:35 The International Progressive MS Alliance is hosting a global webcast on Dec. 11  9:27 Dr. Kathy Zackowski and Mimi Brown discuss the risks and benefits of participating in MS research  10:58 Share this episode  29:52 Have you downloaded the free RealTalk MS app?  30:11 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/379 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com REPORT: Brain Health -- Time Matters https://www.msbrainhealth.org/wp-content/uploads/2024/09/Brain-Health-Time-Matters-2024.pdf VIDEO: Brain Health -- Time Matters https://www.msbrainhealth.org/launch-videos Decoding Immunity: Common Mechanisms of Autoimmunity https://decodingautoimmunity.org REGISTER FOR THE WEBCAST: What We're Learning from Clinical Trials https://www.msif.org/webcast-clinical-trials Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 379 Guests: Dr. Kathy Zackowski and Mimi Brown Privacy Policy

Too often, care partners remain invisible as they deal with the emotional, physical, and even financial burdens that go along with supporting a loved one who's living with multiple sclerosis.  November is National Family Caregivers Month, and I'm devoting this entire episode to a roundtable discussion with four remarkable care partners as they share their insights, experiences, and lessons learned caring for a loved one with MS. You won't want to miss my conversation with Barbara, Marina, Maiya, and Matt. We have a lot to talk about! Are you ready for RealTalk MS??! Giving thanks  :22 This Week: A roundtable discussion with four amazing MS care partners   1:31 Barbara, Marina, Maiya, and Matt discuss their roles as care partners  1:58 Share this episode  33:22 Have you downloaded the free RealTalk MS app?  33:43 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/378 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com The MS Care Partner Connection https://mscarepartnerconnection.com Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 378 Guests: Barbara, Marina, Maiya, and Matt Privacy Policy

There are some people who, once you meet them, it's impossible to forget them. They seem to leave an indelible impression. Lydia Emily is one of those people. Whether it's through her art that occasionally escapes the canvas to be expressed as massive urban murals proclaiming End MS, or through her outspoken MS advocacy. Lydia Emily is a force. Now, along with co-author Lenlee Keep, Lydia Emily has channeled that energy into a book entitled, The Art of Hope: The Life and Art of Lydia Emily. Lydia Emily and her co-author, Lenlee Keep, join me this week to talk about the process of writing the book and some of the issues affecting people with MS that Lydia Emily is passionate about. We'll also tell you about study results that provide an answer to how nerve cells die in MS. We'll share results from a study that shows MS progression may not be directly connected to the number of lesions someone may have. And we'll tell you about research that provides evidence for continuing your MS disease-modifying therapy, no matter your age. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: The Art of Hope   :22 A study uses a novel mouse model to explain how nerve cells die in MS  2:17 Study results show that MS progression may have less to do with the number of lesions and more to do with what's happening inside those lesions  5:23 Study results provide evidence for continuing your DMT, even as you age  9:15 Artist Lydia Emily and co-author Lenlee Keep discuss The Art of Hope: The Life and Art of Lydia Emily  14:17 Share this episode  34:50 Have you downloaded the free RealTalk MS app?  35:11 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/377 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com STUDY: Remyelination Protects Neurons from DLK-Mediated Neurodegeneration https://www.nature.com/articles/s41467-024-53429-5 STUDY: Advanced MRI Measures of Myelin and Axon Volume Identify Repair in Multiple Sclerosis https://onlinelibrary.wiley.com/doi/10.1002/ana.27102 STUDY: Impact of Discontinuing Disease-Modifying Therapies On Healthcare Utilization Among Midlife Patients with Multiple Sclerosis in the United States https://www.jmcp.org/doi/10.18553/jmcp.2024.30.11.1248 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 377 Guests: Lydia Emily and Lenlee Keep Privacy Policy

MS affects almost 3 times as many women as men, often affecting women of childbearing age. In this special episode of RealTalk MS, Dr. Riley Bove answers some of the important questions about the impact of MS on a woman's pregnancy and the impact of pregnancy on a woman's MS. This special episode of RealTalk MS is sponsored by Viatris. SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/V201 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode V201 Guests: Dr. Riley Bove Privacy Policy

On this podcast, we tend to talk a lot about new technologies, emerging treatments, the most recently approved disease-modifying therapies, and even some DMTs that haven't yet been approved.   And in the midst of all that cutting-edge research and evolving science, it's easy to lose sight of the fact that expressive therapies like dance and movement therapy, music therapy, and art therapy have all been shown to help promote self-efficacy, emotional well-being, and motor control in people living with MS. Dr. Francois Bethoux joins me on today's episode to discuss the benefits of integrating dance and movement therapy, music therapy, and art therapy into your treatment plan to help manage your MS symptoms and enhance your well-being. November is National Family Caregivers Month, and we're sharing a neat piece of tech that can not only make life easier for MS caregivers but can make life better for their care recipients, as well. CEO Costin Tuculescu introduces us to his company's new device, OnScreen. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Adding expressive therapies to your MS treatment plan  :22 OnScreen CEO Costin Tuculescu explains how OnScreen can help people with MS and their caregivers  1:34 Dr. Francoi Bethoux discusses the benefits of dance therapy, music therapy, and art therapy for people living with MS  17:45 Share this episode  31:47 Have you downloaded the free RealTalk MS app?  32:06 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/376 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com OnScreen https://onscreeninc.com Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 376 Guests: Costin Tuculescu and Dr. Francois Bethoux Privacy Policy

Being a teenager is hard. So, imagine for a moment that in addition to everything else that teenagers have to endure, you're a teenager who's been diagnosed with MS. Your ability to participate in after-school activities or just hang out with your friends is impacted by MS-related fatigue. The typical adolescent anxiety over something someone posted on social media evolves into depression. And cognitive issues begin to make it harder for you in the classroom. This is an unfortunate reality for many adolescents who are living with MS. Joining me to discuss how MS affects adolescents and how families can help manage MS is Dr. Ann Yeh. Dr. Yeh is a Professor of Pediatric Neurology at the University of Toronto and the director of the MS and Neuroinflammatory Disorders Program and Fellowship Program at the University of Toronto's Hospital for Sick Children, known as SickKids.  We'll also tell you about a new online resource for MS care partners. We'll share the results of a study that explored how different symptom management responsibilities impact MS care partners. We'll share details of a study that demonstrated positive results in improving MS-related fatigue. We'll tell you about the discovery of a plant-based molecule that is showing promise in promoting myelin repair. And we're sharing surprising research results that have more than doubled the prevalence of MS in Australia. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Managing Teenage MS  :22 November is National Family Caregivers Month  1:47 You're invited to preview MS Care Partner Connection  3:40 A study reveals the most challenging MS symptoms for care partners to manage  6:33 Study results show Modafinil and cognitive behavioral therapy are both effective in managing MS fatigue  7:25 Researchers discover a plant-based molecule that may be effective in promoting myelin repair  9:46 Prevalence of MS in Australia more than doubled over an 11-year period   12:54 Dr. Ann Yeh discusses the challenges of MS among adolescents  16:05 Share this episode  31:15 Have you downloaded the free RealTalk MS app?  31:36 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/375 ADD YOUR VOICE TO THE CONVERSATION I've always considered the RealTalk MS podcast a conversation. This is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com The MS Care Partner Connection https://mscarepartnerconnection.com Addressing the Needs of Multiple Sclerosis Caregivers from Diagnosis Onward: The Development of a Comprehensive Online Caregiver Protocol https://meridian.allenpress.com/ijmsc/article/25/6/273/496788/Addressing-the-Needs-of-Multiple-Sclerosis STUDY: Symptom Management Among Multiple Sclerosis Care Partners in Canada https://meridian.allenpress.com/ijmsc/article/25/6/281/496792/Symptom-Management-Among-Multiple-Sclerosis-Care STUDY: Comparative Effectiveness of Cognitive Behavioural Therapy, Modafinil, and Their Combination for Treating Fatigue in Multiple Sclerosis (COMBO-MS): A Randomised, Statistician-Blinded, Parallel-Arm Trial https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(24)00354-5/abstract STUDY: Distinct Chemical Structures Inhibit the CEMIP Hyaluronidase and Promote Oligodendrocyte Progenitor Cell Maturationhttps://www.jbc.org/article/S0021-9258(24)02418-9/fulltext STUDY: Significantly Increasing Multiple Sclerosis Prevalence in Australia from 2010 to 2021 https://journals.sagepub.com/doi/10.1177/13524585241265890 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 375 Guest: Dr. Ann Yeh Privacy Policy

Learning to live with MS is learning to live with loss. For some, those losses may be minor and seem relatively insignificant. For others, those losses can be huge and life-altering. The definition of grief is an emotional response to a significant loss. It's not unusual to grieve over those things in your life that have been lost due to MS. In fact, healthy grieving is a necessary emotional step to moving forward in life. Dr. Holly Hendin, a faculty physician and psychiatrist at St. Joseph's Hospital Medical Group Outpatient Behavioral Health in Phoenix, Arizona, joins me to explore grieving when you live with MS. We'll also share the results of a study that show other health conditions can have a negative impact on MS disease activity, like relapses and disability worsening. And we're sharing the details of the $4.6 million dollar investment the National MS Society is making in research focused on myelin repair. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Grieving when you're living with MS  :22 A study shows how other health conditions may cause MS to worsen  2:00 The National MS Society is investing $4.6 million dollars in research focused on myelin repair  6:21 Dr. Holly Hendin helps us understand the importance of healthy grieving when you're living with MS  9:39 Share this episode  35:30 Have you downloaded the free RealTalk MS app?  35:50 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/374 ADD YOUR VOICE TO THE CONVERSATION I've always considered the RealTalk MS podcast a conversation. This is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com STUDY: Comorbidity and Disease Activity in Multiple Sclerosis https://jamanetwork.com/journals/jamaneurology/fullarticle/2823966 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 374 Guest: Dr. Holly Hendin Privacy Policy

Now that he's had a chance to digest all of the research presented at ECTRIMS, Dr. Bruce Bebo, the National MS Society's Executive Vice President of Research, is back to share the key research presented at the largest MS research conference in the world. This episode of RealTalk MS is the perfect follow-up to my initial conversation with Bruce, which occurred just minutes after ECTRIMS ended. (If you missed our conversation, you may want to check out Episode 369 of RealTalk MS.) We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Part 2 of our coverage of ECTRIMS 2024  :22 Dr. Bruce Bebo shares the key research presented at ECTRIMS  1:06 Share this episode  26:13 Have you downloaded the free RealTalk MS app?  26:31 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/373 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS Episode 369: ECTRIMS 2024 with Kristine Werner Ozug and Dr. Bruce Bebo https://realtalkms.com/369 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 373 Guest: Dr. Bruce Bebo Privacy Policy

Open enrollment is underway! And if you're one of the 25% of people living with MS who get their coverage through Medicare, there are some major changes coming in 2025. So, it's especially important that you review your prescription drug coverage to make sure you're enrolled in the Medicare Part D plan that's best for you.   Sarah Anderson, pharmacist and senior director of clinical resources and programming at the National MS Society, joins me to help us decipher those changes and navigate the sometimes confusing world of health insurance. We'll also tell you about a research team that's editing human DNA to promote myelin repair. We'll share the results of a study that offers some surprising evidence about the quality of MS care for women in France.  We'll explain why a study that shows people with MS are at a higher risk for being diagnosed with cancer may not be as scary as it sounds. In my conversation with Dawn Schottlandt, you'll hear the story of In My Running Shoes and learn how people with MS and other disabilities can benefit from their work. And we'll give you all the details about artist Elizabeth Jameson's exhibition, An Intimate Journey, which opens in New York on Saturday, October 19th. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: Open Enrollment has begun  :22 Researchers succeed in editing human DNA to promote myelin repair  1:14 Research reveals women with MS are often undertreated in France  3:38 Are people with MS more likely to develop cancer?  6:18 Dawn Schottlandt explains why she founded In My Running Shoes and how you might benefit  9:12 Elizabeth Jameson's art exhibition, An Intimate Journey, opens in New York on Saturday  16:01 Sarah Anderson explains the changes to Medicare in 2025  18:04 Share this episode  27:56 Have you downloaded the free RealTalk MS app?  28:16 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/372 ADD YOUR VOICE TO THE CONVERSATION I've always considered the RealTalk MS podcast a conversation. This is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com STUDY: CRISPR-Edited ES-Derived Oligodendrocyte Progenitor Cells Improve Remyelination in Rodents https://www.nature.com/articles/s41467-024-52444-w STUDY: Cancer Risk Among Patients with Multiple Sclerosis https://www.neurology.org/doi/10.1212/WNL.0000000000209885 In My Running Shoes https://inmyrunninigshoes.org Elizabeth Jameson exhibition at the Positive Exposure Gallery https://positiveexposure.org/event/41014 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 372 Guests: Dawn Schottlandt and Sarah Anderson Privacy Policy

In the seven years that I've been hosting RealTalk MS, no one has ever described a mobility device as life-changing. That is until listener Dee Ecklund reached out to tell me about her experience with the Alinker.  One of my goals in producing this podcast is to introduce the RealTalk MS listener community to people who are difference-makers. And Dee's initial DM led to my conversation with Dee and the inventor of the Alinker, a true difference-maker, BE Alink.  The National MS Society's 3rd annual Hispanic/Latinx MS Experience Summit is just two days away! We're sharing all the details, including how you can register for this free virtual event. And I'm sharing my thoughts following attending the University of Pittsburgh's bi-annual caregiver research conference. We have a lot to talk about! Are you ready for RealTalk MS??! The Hispanic/Latinx MS Experience Summit is two days away!  :22 Don't miss our ECTRIMS Extra Conversations  1:38 Thoughts following attending the caregiver research conference at the University of Pittsburgh  2:15 Dee and BE discuss all things Alinker (including how you can get yours!)  9:26 Share this episode  37:02 Have you downloaded the free RealTalk MS app?  37:23 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/371 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Hispanic/Latinx MS Experience Summit https://nationalmssociety.org/resources/get-support/education-programs-and-library/hispanic-latinx-ms-experience MS Care Partner Connection https://mscarepartnerconnection.com The Alinker https://thealinker.com Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 371 Guests: Dee Ecklund and BE Alink Privacy Policy

With more than 9,000 MS researchers and clinicians in attendance, the 2024 ECTRIMS meeting in Copenhagen was the largest MS research conference in the world. During the meeting, I had an opportunity to talk with some of the best and brightest minds in MS research and clinical practice. This is your invitation to listen in on my ECTRIMS EXTRA conversation with Dr. Jiwon Oh. Dr. Oh is a neurologist, scientist, and the Medical Director of the Barlo Multiple Sclerosis Program at St. Michael's Hospital in Ontario, Canada. Dr. Oh is also the Principal Investigator in Gemini, the Phase 3 clinical trial for Tolebrutinib and relapsing-remitting MS. At ECTRIMS, Dr. Oh shared the outcome of the Gemini clinical trial. We have a lot to talk about! Are you ready for RealTalk MS??! SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/ectrims244 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS ECTRIMS Extra Guest: Dr. Jiwon Oh Privacy Policy

In 2020, the National MS Society convened the Pathways to Cures Think Tank. I shared news and interviews from what I considered a historic meeting back in Episode 125 of RealTalk MS.  The information shared and the work generated by that Think Tank led to the Pathways to Cures Global Summit in 2023. In Episodes 297and 298 of RealTalk MS, I shared news and interviews from what I described as yet another historic meeting. The Pathways to Cures Research Roadmap has been updated, and I'm devoting this week's episode of RealTalk MS to my conversation with the National MS Society's Executive Vice-President of Research, Dr. Bruce Bebo, and the MS Society's Vice-President of Global Initiatives, Shawna Golden, to bring us up to date on how this global MS research initiative has been refined and enhanced and how it's resetting the global MS research agenda. We have a lot to talk about! Are you ready for RealTalk MS??! This Week: The Pathways to Cures research roadmap has been updated  :22 Dr. Bruce Bebo and Shawna Golden discuss the refined and enhanced Pathways to Cures research roadmap  2:34 Share this episode  29:58 Have you downloaded the free RealTalk MS app?  30:18 SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/370 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS Episode 125: From the Pathways to Cures Think Tank https://realtalkms.com/125 RealTalk MS Episode 297: From the Pathways to Cures Global Summit (Part 1) https://realtalkms.com/297 RealTalk MS Episode 298: From the Pathways to Cures Global Summit (Part 2) https://realtalkms.com/298 Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Episode 370 Guests: Dr. Bruce Bebo, Shawna Golden Privacy Policy

With more than 9,000 MS researchers and clinicians in attendance, the 2024 ECTRIMS meeting in Copenhagen was the largest MS research conference in the world. During the meeting, I had an opportunity to talk with some of the best and brightest minds in MS research and clinical practice. This is your invitation to listen in on my ECTRIMS EXTRA conversation with Dr. Peter Calabresi. Dr. Peter Calabresi is the Director of the Division of Neuroimmunology and the Director of the Multiple Sclerosis Center at Johns Hopkins Medicine. He is the principal investigator on several clinical trials and oversees research projects focused on developing new anti-inflammatory and neuroprotective therapies for MS. At ECTRIMS, Dr. Calabresi co-chaired what was probably the most highly anticipated presentation at this year's conference: the unveiling of updated criteria for diagnosing MS. We have a lot to talk about! Are you ready for RealTalk MS??! SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/ectrims243 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS ECTRIMS Extra Guest: Dr. Peter Calabresi Privacy Policy

With more than 9,000 MS researchers and clinicians in attendance, the 2024 ECTRIMS meeting in Copenhagen was the largest MS research conference in the world. During the meeting, I had an opportunity to talk with some of the best and brightest minds in MS research and clinical practice. This is your invitation to listen in on my ECTRIMS EXTRA conversation with Rachel Horne and Professor Kerstin Hellwig. Professor Kerstin Hellwig is the 2024 recipient of the Rachel Horne Prize for Women's Research in MS. Professor Hellwig was honored at ECTRIMS for her pioneering research into understanding and navigating the safety of approved treatments for women with MS before, during, and after pregnancy.  Professor Hellwig is a senior consultant at St Josef Hospital, Ruhr University, Bochum,  Germany, specializing in MS and neuroimmunology, and is a leading clinician-scientist in the field of MS and family planning. We have a lot to talk about! Are you ready for RealTalk MS??! SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/ectrims242 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS ECTRIMS Extra Guests: Rachel Horne, Professor Kerstin Hellwig Privacy Policy