Podcasts about texas southwestern medical center

In this Leveling Up episode of the PRS Global Open Deep Cuts podcast, Dr. Christopher Attinger discusses how to build a successful wound center, the benefits of including psychiatry in a wound care service, the importance of removing all indurated tissues during a debridement, why placing a skin graft on granulation tissue is actually a bad idea, the benefits of bypass surgery over angioplasty, how to know when Integra has good take, his go-to local flaps for the foot and ankle and why he doesn't like reverse sural flaps. He also discusses the nuances of performing a TMA and a BKA, why he never uses deep sutures in any wound closure, how TMR has been a game changer in his practice, the rating system for medial arterial calcinosis that predicts the risk of complications, and how he has structured the service to maximize resident education. Read a classic PRS Global Open article by Dr. Attinger and his colleagues, “The Effect of Positive Postdebridement Cultures on Local Muscle Flap Reconstruction of the Lower Extremity”: https://bit.ly/DebridementFXLE  Dr. Christopher Attinger is a Professor in the Plastic and Reconstructive Surgery Department at Georgetown University Medical Center, and the Director of the Center for Wound Healing at MedStar Georgetown University Hospital. He served two tours of duty in Vietnam, as a lieutenant in the 82nd Airborne and the 101st Airborne divisions, and was honorably discharged with a Purple Heart and Bronze Star. He received his medical degree from Yale University, and then completed a residency in general surgery and fellowship in vascular surgery at Brigham and Women's Hospital in Boston, and a plastic surgery residency and hand surgery fellowship at New York University. After completing his training, he joined the faculty at Georgetown, and has been there ever since. In 2007, Dr. Attinger started an annual limb salvage conference to bring together all the members of the limb salvage community to exchange ideas and innovations.  Your host, Dr. Puru Nagarkar, is a board-certified plastic and hand surgeon, and Associate Professor of Plastic Surgery at the University of Texas Southwestern Medical Center in Dallas. The views expressed by hosts and guests are their own and do not necessarily reflect the official policies or positions of ASPS. #PRSGlobalOpen #DeepCutsPodcast #PlasticSurgery #LevelingUp

Support your health journey with our private practice! Explore comprehensive lab testing, functional assessments, and expert guidance for your wellness journey. Find exclusive offers for podcast listeners at nutritionwithjudy.com/podcast. _____Dr. Peter McCullough and I delve into the efficacy of vaccines, COVID-19 shots, the role of early treatment protocols, and much more. Listen to the full interview to learn more.Dr. Peter A. McCullough is an American internist, cardiologist, and epidemiologist. He earned his Bachelor of Science from Baylor University in 1984 and his Doctor of Medicine from the University of Texas Southwestern Medical Center in 1988. Throughout his career, Dr. McCullough has been recognized for his extensive research, particularly in the fields of cardiovascular and kidney diseases.Bird flu outbreak and rising egg pricesMeasles vaccine efficacy and safetyConcerns about vaccine side effectsEarly intervention in vaccineAutism studies and vaccinesInjury from standard medical interventions and immune differencesUpdates on COVID-19Thoughts on booster shotsWuhan leak mistake cover-up or profit Where to find Dr. Peter McCullough_____EPISODE RESOURCESNwJ COVID-19 and Vaccine Research Studies2018-19 Flu Vaccine Effectiveness in ages 50-651964 Smoking - Surgeon GeneralJapan Bans MMR Vaccine (Measles, Mumps, Rubella Vaccine)Reduced Risk of Glioma Brain Cancer with Chickenpox Exposure: Here and Here Infant Mortality Risks and Vaccines: Here and HereVaricella Vaccine RisksLive Attenuated Vaccines Risk vs Reward _____DR. PETER MCCULLOUGH RESOURCES- X  - McCullough Foundation - Publications - America Out Loud Talk Radio- The Wellness Company - The Focal Points- The Courage to Face COVID-19 _____WEEKLY NEWSLETTER 

In this Leveling Up episode of the PRS Global Open Deep Cuts podcast, Dr. Scott Hansen talks about his new role as Chair of Plastic Surgery at UCSF, his experience as a program director, and his leadership approach to resident training. He also shares insights on performing awake hand surgeries, his role as a team hand surgeon for the San Francisco Giants, and the unique considerations when treating hand injuries in professional athletes. Dr. Hansen explores the surprising differences between college women's basketball and Major League Baseball, how his practice of hand surgery has evolved, the field of spinoplastic surgery, and why he finds treating hidradenitis rewarding. He also reflects on the lessons he's learned from Drs. Steve Mathes, Neil Ford Jones, and Prosper Benhaim. Read a recent PRS Global Open article by Dr. Hansen and his colleagues, “A Pilot Randomized Clinical Trial of Early Ambulation after Groin Reconstruction with Sartorius Muscle Flaps“: https://bit.ly/WalkingAfterGroinRecon  Dr. Scott Hansen is a Professor, Chief of the Division of Plastic Surgery, and the Program Director for the Plastic Surgery Residency at the University of California San Francisco. He also serves as the Chief of Hand and Microvascular surgery and the Director of the Microsurgery fellowship. He graduated from Eastern Virginia Medical School, and then completed a Plastic Surgery residency and a post-doctoral research fellowship at UCSF followed by a Hand and Microvascular surgery fellowship at UCLA. He joined UCSF as full-time faculty, and recently became the Chief of the Division of plastic surgery there. He is the Hand and Microsurgery section editor for the Annals of Plastic Surgery. He is the team hand surgeon for the San Francisco Giants. He has remained involved in basic science research, with a focus in wound healing, hemangiomas, and limb development. Your host, Dr. Puru Nagarkar, is a board-certified plastic and hand surgeon, and Associate Professor of Plastic Surgery at the University of Texas Southwestern Medical Center in Dallas. #PRSGlobalOpen #DeepCutsPodcast #PlasticSurgery #LevelingUp

Just a couple of weeks ago, 1,800 scientists, clinicians, postdoctoral fellows, and medical residents gathered in West Palm Beach, Florida, for the Americas Committee for Treatment and Research in Multiple Sclerosis annual meeting, better known as the ACTRIMS Forum. Dr. Darin Okuda is the Director of the Multiple Sclerosis and Neuroimmunology Imaging Program, the Director of  Neuroinnovation, and the Deputy Director of the Multiple Sclerosis Program and Clinical Center for Multiple Sclerosis at University of Texas Southwestern Medical Center. At the ACTRIMS Forum, we talked with Dr. Okuda about the impact of artificial intelligence on MS care, how to go about preventing MS, and a frightening case study of what went wrong with an MS patient's generic disease-modifying therapy.  We have a lot to talk about! Are you ready for RealTalk MS??! SHARE THIS EPISODE OF REALTALK MS Just copy this link & paste it into your text or email: https://realtalkms.com/actrims01 ADD YOUR VOICE TO THE CONVERSATION I've always thought about the RealTalk MS podcast as a conversation. And this is your opportunity to join the conversation by sharing your feedback, questions, and suggestions for topics that we can discuss in future podcast episodes. Please shoot me an email or call the RealTalk MS Listener Hotline and share your thoughts! Email: jon@realtalkms.com Phone: (310) 526-2283 And don't forget to join us in the RealTalk MS Facebook group! LINKS If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com RealTalk MS on YouTube https://www.youtube.com/@RealTalkMS Join the RealTalk MS Facebook Group https://facebook.com/groups/realtalkms Download the RealTalk MS App for iOS Devices https://itunes.apple.com/us/app/realtalk-ms/id1436917200 Download the RealTalk MS App for Android Deviceshttps://play.google.com/store/apps/details?id=tv.wizzard.android.realtalk Give RealTalk MS a rating and review http://www.realtalkms.com/review Follow RealTalk MS on Twitter, @RealTalkMS_jon, and subscribe to our newsletter at our website, RealTalkMS.com. RealTalk MS Bonus Episode Guest: Dr. Darin Okuda Privacy Policy

Can you believe it's been 3 YEARS since we first had a conversation with Dr. Shin Beh about vestibular migraine? Dr. Abbie Ross, PT, NCS, and Dr. Danielle Tolman, PT catch up and discuss some new updates in vestibular migraine treatment approaches. About Dr. BehDr. Beh completed his neurology residency training at the University of Texas Southwestern Medical Center. His fellowship training consisted of: Neuroimmunology & Multiple Sclerosis, Neuro-otology, and Neuro-ophthalmology. His fellowship training was completed at three centers – the University of Texas Southwestern Medical Center, Johns Hopkins University Hospital, and New York University Medical Center. After completion of his fellowship training, he returned to the University of Texas Southwestern Medical Center to to set up its very first Vestibular & Neuro-Visual Disorders Clinic. This Clinic was built to help care for the many people suffering from neurological disorders that caused vertigo, dizziness, and imbalance. Initially, he divided his time between multiple sclerosis and vestibular disorders. After realizing there was a far greater need among people with vestibular disorders, he focused solely on this area, and joined the Headache & Facial Pain Program. Where to find Dr. Beh: https://www.vestibularmd.com/ Hosted by:

In this Leveling Up episode of the PRS Global Open Deep Cuts podcast, Dr. David Song discusses several key topics. He highlights the unique role that plastic surgeons can play as leaders within surgery and the broader medical system. Dr. Song emphasizes that being an excellent clinician with "street cred" is essential for effective leadership. He also talks about how to create and guide change effectively, and the importance of active listening in both surgery and patient care. Additionally, Dr. Song shares insights on preoperative and anesthetic modifications that can improve patient recovery after microsurgery. He explains why he always uses two separate venous systems in a DIEP flap and provides technical details on arterial anastomosis. He also discusses the latissimus immediate fat transfer flap for non-microsurgical autologous breast reconstruction. Finally, Dr. Song reflects on how being right and cultivating durable relationships can sometimes be at odds with each other. Read a classic PRS Global Open article by Dr. Song and Dr. James Economides, “Latissimus Dorsi and Immediate Fat Transfer (LIFT) for Complete Autologous Breast Reconstruction:”  https://bit.ly/LIFT_Breast_Recon_GOX Dr. David Song is the Chief Medical Officer and Vice President of Medical Affairs for MedStar Georgetown University Hospital, as well as a Professor and former Chairman of the Department of Plastic Surgery, and the former Chief of Surgery at Georgetown University School of Medicine. He completed residencies in general surgery and plastic surgery as well as a microsurgery fellowship at the University of Chicago, where he stayed on first as a faculty member, and then as the Chief of Plastic Surgery. He moved to Georgetown to become the Chair of Plastic Surgery in 2017, before recently moving into the role of Chief Medical Officer and VP of Medical Affairs. Among his many leadership roles in plastic surgery, he is a former President of the American Society of Plastic Surgeons, former Chair of the American Board of Plastic Surgery, and current chair of the ACGME Plastic Surgery Residency Review Committee. Your host, Dr. Puru Nagarkar, is a board-certified plastic and hand surgeon, and Associate Professor of Plastic Surgery at the University of Texas Southwestern Medical Center in Dallas. #PRSGlobalOpen #DeepCutsPodcast #PlasticSurgery #LevelingUp

Guest: Dr. Richard Noel, MDEarn 0.1 ASHA CEU for this episode with Speech Therapy PD: https://www.speechtherapypd.com/course?name=The-Medical-Domain-of-Pediatric-Feeding-DisorderIn this episode, Dr. Richard Noel joins the discussion to shed light on Pediatric Feeding Disorder (PFD) and its medical domain. Dr. Noel shares his journey to becoming a pediatric GI specialist and explores the critical components of managing PFD. Key topics include the importance of growth and nutrition, management of upper GI tract issues, and the significance of airway and lung concerns. Dr. Noel also addresses common misconceptions about reflux in infants and the use of various appetite stimulants such as ciproheptadine and mirtazapine. Viewers will gain valuable insights into constipation management, the role of scheduled toileting, and the importance of multidisciplinary care in treating PFD. The conversation underscores the need for better medical understanding and care strategies for children with PFD.Timeline:00:00 Introduction and Guest Welcome01:41 Journey to Becoming a Pediatric Gastroenterologist05:32 Understanding Pediatric Feeding Disorders06:51 Medical Domain of PFD: Key Considerations08:24 Addressing Nutritional Concerns14:17 Managing Constipation in PFD21:39 Behavioral Strategies for Feeding23:36 Family Involvement in Feeding Therapy26:04 Family Routines and Feeding Therapy26:47 Medications for Appetite Stimulation27:03 Ciproheptadine: Uses and Effects31:18 Mirtazapine: An Appetite Stimulant34:49 Megastrol: A Powerful Appetite Stimulant37:07 Managing GI Issues in Children38:03 Reflux and Vomiting in Infants43:09 Cyclical GI Disorders: Abdominal Migraines and More47:20 The Role of Multidisciplinary Teams in Pediatric Care48:56 Challenges in Pediatric Feeding Disorder Education53:46 Advocacy and Access to Multidisciplinary CareAbout the Guest: Dr. Richard Noel was born in Mexico City and grew up in San Antonio, TX. He has MD/PhD degrees from the University of Texas Southwestern Medical Center in Dallas and did a residency in Pediatrics at Wake Forest University in NC. He trained in Pediatric Gastroenterology at Cincinnati Children's Hospital Medical Center, where he developed an interest in working with children with pediatric feeding disorders. He worked for 10 years at the Children's Hospital of Wisconsin with Dr. Colin Rudolph and then transitioned to Duke University, where is currently Division Chief for Pediatric Gastroenterology, Hepatology, and Nutrition.Watch this Interview on YouTube: https://youtu.be/NVGPdIzfobs

Dr. Joseph S. Takahashi is Professor and Chair of Neuroscience and the Loyd B. Sands Distinguished Chair in Neuroscience at the University of Texas Southwestern Medical Center. He is also an Investigator in the Howard Hughes Medical Institute. Joe and his lab members are trying to better understand the biological clocks in our bodies that control our 24-hour schedules. Within each of us are internal clocks that are genetically controlled. A special set of genes within nearly all of our cells turns on and off each day to regulate a wide variety of biological functions, and Joe is studying these genes and how they contribute to our biological rhythms. Functions influenced by our biological clocks include our sleep schedules, blood sugar, body temperature, liver metabolism, and many other aspects of our physiology. When Joe isn't at work, he enjoys playing tennis, skiing, hiking, eating delicious food, and drinking great wine. Joe received his B.A. in biology from Swarthmore College and he was awarded his Ph.D. in neuroscience from the University of Oregon in Eugene. Afterwards, he conducted postdoctoral research as a pharmacology research associate at the National Institute of Mental Health. Before moving to UT Southwestern, Joe served on the faculty of Northwestern University for 26 years. Over the course of his career, Joe has received numerous awards and honors including the Honma Prize in Biological Rhythms Research, the NSF Presidential Young Investigator Award, the Searle Scholars Award, the Bristol-Myers Squibb Unrestricted Grant in Neuroscience, the C. U. Ariens Kappers Medal, the Outstanding Scientific Achievement Award from the Sleep Research Society, the W. Alden Spencer Award in Neuroscience from Columbia University, and the Peter C. Farrell Prize in Sleep Medicine from the Harvard Medical School Division of Sleep Medicine. He has also been elected as a Fellow of the American Academy of Arts and Sciences, a Fellow of the American Association for the Advancement of Science, a Member of the National Academy of Sciences, a Member of the National Academy of Medicine, and an Honorary Member of The Japanese Biochemical Society. In our interview, Joe shared his experiences in life and science.

In today's episode, we had the pleasure of speaking with David Gerber, MD, a professor in the Department of Internal Medicine at the University of Texas Southwestern Medical Center, a member of its Division of Hematology/Oncology, and co-director of Education and Training for the Harold C. Simmons Comprehensive Cancer Center in Dallas. In our exclusive interview, Dr Gerber discussed the evolving role of antibody-drug conjugates (ADCs) in non–small cell lung cancer (NSCLC), focusing on findings from key clinical trials. He highlighted results from the phase 3 TROPION-Lung01 trial (NCT04656652), which demonstrated a modest improvement in progression-free survival with datopotamab deruxtecan-dlnk (Datroway), a TROP2-directed ADC, compared with docetaxel in patients with previously treated advanced NSCLC. He also emphasized the toxicity profile of TROP2-directed ADCs, particularly gastrointestinal toxicities and myelosuppression. Dr Gerber also reviewed the phase 2 HERTHENA-Lung01 trial (NCT04619004) evaluating patritumab deruxtecan in patients with EGFR-mutant NSCLC and the phase 2 DESTINY-Lung02 trial (NCT04644237) assessing fam-trastuzumab deruxtecan-nxki (Enhertu) in those with HER2-mutant NSCLC. Dr Gerber reflected on the shared DXd payload of these ADCs, highlighting its implications for toxicity and efficacy, as well as open questions regarding treatment sequencing and resistance mechanisms.

In this Leveling Up episode of the PRS Global Open Deep Cuts, Dr. Michael Bentz discusses connecting with patients and building trust and rapport, the changes in pediatric plastic surgery over the last few decades, his approach to the syndactyly patient and the use of full thickness skin grafts, the nuances of placing upper and lower extremity splints in kids, teaching and giving feedback to residents, interviewing and selecting applicants for the residency program, what he considers to be a successful resident, and the lessons he learned from his mentors at PIttsburgh and Wisconsin.  Read a classic PRS Global Open article by Dr. Bentz and colleagues, “What Influences a Plastic Surgery Resident to Pursue an Academic Career?”: https://bit.ly/PSAcadCareerInfluences_GOX    Dr. Michael Bentz is a Professor of Surgery, Pediatrics, and Neurosurgery at the University of Wisconsin School of Medicine and Public Health in Madison, Wisconsin. He recently stepped down as the chief of the Division of Plastic after 24 years and continues to serve as the Vice Chair in the Department of Surgery. A native of Pennsylvania, Dr. Bentz completed medical school and a General Surgery residency at Temple University in Philadelphia, followed by a plastic surgery residency and a microvascular research fellowship at the University of Pittsburgh Medical Center. He stayed on at Pitt and became the residency program director, but left for Wisconsin in 1999 and has remained a fixture at the University of Wisconsin for the last 25 years, building a broad reconstructive practice including pediatric hand surgery; cleft lip and palate surgery; and general reconstruction of the chest, abdominal wall, extremity and head and neck in adults and children.  Dr. Bentz has served as Chair of the American Board of Plastic Surgery, as an executive committee member for the Association of Academic Chairmen in Plastic Surgery, and has co-edited the two-volume book, Principles and Practice of Pediatric Plastic Surgery. He received the Honorary Citation Award from the American Society of Plastic Surgeons in 2018. Your host, Dr. Puru Nagarkar, is a board-certified plastic and hand surgeon, and Associate Professor of Surgery at the University of Texas Southwestern Medical Center in Dallas. #PRSGlobalOpen #DeepCutsPodcast #PlasticSurgery #LevelingUp

In this Leveling Up episode of the PRS Global Open Deep Cuts Podcast, Dr. Azari discusses the nuances of bread and butter hand surgery procedures like carpal tunnel and Dupuytren's fasciectomies, his approach to providing trainees with gradually increasing levels of responsibility and autonomy, how he builds rapport with patients and personalizes his approach to each patient's needs and goals, why it's sometimes important to go against your instincts when dealing with problematic patients, his interest in and lessons learned from hand transplantation, and why patients can be a bit like circling helicopters.   Dr. Kodi Azari is a Professor of Orthopaedic Surgery and Plastic Surgery at UCLA Medical center in Los Angeles, California. He serves as the Chief of Reconstructive Transplantation as well as the Medical Co-Director of Operation Mend which is a UCLA program aimed at providing complex reconstructive surgery for wounded service members injured in Operations Enduring Freedom and Iraqi Freedom.   Dr. Azari completed General Surgery and Plastic Surgery training at the University of Pittsburgh Medical Center, a Tissue Engineering Fellowship at Carnegie Mellon University, and a Hand and Microsurgery Fellowship at UCLA. He has been one of the lead surgeons on 7 hand transplantation operations including the first double hand transplantation and first arm transplantation performed in the United States.   He is a founding member of the American Society for Reconstructive Transplantation, and has served as an Associate Editor for the “Annals of Plastic Surgery,” Guest Editor for “Current Concepts in Organ Transplantation,” and contributing editor for the “Yearbook of Hand and Upper Limb Surgery.”   Your host, Dr. Puru Nagarkar, is a board-certified plastic and hand surgeon, and Associate Professor of Surgery at the University of Texas Southwestern Medical Center in Dallas.   #PRSGlobalOpen #DeepCutsPodcast #PlasticSurgery #LevelingUp

Send us a textIn this episode, Ben and Daphna are joined by Dr. Vishal Kapadia, neonatologist at the University of Texas Southwestern Medical Center, to discuss oxygen use in the delivery room and the “Goldilocks principle” of finding the right balance—not too much, not too little. Dr. Kapadia shares insights from his research on oxygen targets, the challenges of defining evidence-based practices, and the role of personalized care for preterm and term infants. With emerging studies and ongoing trials, this conversation sheds light on how precision in oxygen delivery can impact neonatal outcomes.As always, feel free to send us questions, comments, or suggestions to our email: nicupodcast@gmail.com. You can also contact the show through Instagram or Twitter, @nicupodcast. Or contact Ben and Daphna directly via their Twitter profiles: @drnicu and @doctordaphnamd. The papers discussed in today's episode are listed and timestamped on the webpage linked below. Enjoy!

Dr. Antonio is Chief Executive Officer and Co-founder of the International Society of Sports Nutrition, an academic nonprofit dedicated to the science and application of sports nutrition and supplementation. In addition, he is the Co-founder and Vice President of the Society for Neurosports, an academic nonprofit with a focus on sports neuroscience. Dr. Antonio earned his PhD and completed a post-doctoral research fellowship at the University of Texas Southwestern Medical Center in Dallas. He has published over 100 peer-reviewed papers as well as 15 books. His current areas of research include: dietary supplements (e.g., creatine, protein, etc.), sports neuroscience and human performance. He is currently a Professor at the Nova Southeastern University in Davie, Florida and serves on the Advisory Board of Forbes Health. - www.sportsnutritionsociety.org Work with RAPID Health Optimization Links: Dr. Jose Antonio on Instagram Anders Varner on Instagram Doug Larson on Instagram Coach Flavia Pereira on Instagram

A high-profile committee hearing at the Texas Capitol proceeded Monday without its main attraction: Robert Roberson, a man on death row whose execution was delayed last week after a bipartisan group of lawmakers issued a subpoena compelling his testimony. In other news, Federal labor regulators said Monday that the University of Texas Southwestern Medical Center has agreed to pay $900,000 to resolve complaints that the school systemically discriminated against 6,100 Black applicants over a two-year period; Early voting for the Nov. 5 election began yesterday and ends Friday, Nov. 1. In Texas, all registered voters can cast a ballot in person during the early voting period. Dallas Morning News journalists visited most of the 70 early voting centers to check on the conditions of buildings and access to parking and mass transit.  For resources to help you cast your ballot with confidence, subscribe to Back to the Ballot, a personalized voter education newsletter, and view The Dallas Morning News voter guide; And after weeks of wondering, Mavericks fans who need a streaming option to watch the team's local broadcasts are getting their wish, albeit for a price. Learn more about your ad choices. Visit podcastchoices.com/adchoices

BUFFALO, NY- October 22, 2024 – A new #research paper was #published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 19 on September 26, 2024, entitled, “Use of the senolytics dasatinib and quercetin for prevention of pelvic organ prolapse in a mouse animal model.” Pelvic organ prolapse is a common condition among women in the U.S., with a 13% estimated risk of requiring surgery by age 80. Senolytic agents like dasatinib and quercetin (D+Q) target age-related cellular senescence and reduce senescent cell activity in various disease processes. In their paper, researchers Erryn Tappy, Haolin Shi, Jessica Pruszynski, and Maria Florian-Rodriguez from the University of Texas Southwestern Medical Center, Department of Obstetrics and Gynecology in Dallas, utilized a mouse model of pelvic organ prolapse, Fibulin-5 knockout (Fbln-5-/-) mice, to assess the ability of D+Q to prevent development of prolapse. The D+Q injections administered did not result in significant differences in prolapse development but did reduce cellular senescence markers in Fbln-5-/- mice. This suggests senolytic agents may help mitigate the role of cellular senescence in tissue dysfunction associated with prolapse. The researchers suggest that further studies are needed to determine optimal timing, dosage, and delivery of senolytics for prolapse prevention. "This study represents one of the first to evaluate the impact of senolytic agents D+Q on the clinical development of pelvic organ prolapse and expression of proteins associated with cellular senescence in a mouse model.” DOI - https://doi.org/10.18632/aging.206120 Corresponding author - Maria Florian-Rodriguez - Maria.Florian-Rodriguez@UTSouthwestern.edu Video short - https://www.youtube.com/watch?v=kTQfjhubx_4 Sign up for free Altmetric alerts about this article - https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206120 Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts Keywords - aging, pelvic organ prolapse, cellular senescence, senolytic agents, animal model About Aging-US The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population. The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.) Please visit our website at https://www.Aging-US.com​​ and connect with us: Facebook - https://www.facebook.com/AgingUS/ X - https://twitter.com/AgingJrnl Instagram - https://www.instagram.com/agingjrnl/ YouTube - https://www.youtube.com/@AgingJournal LinkedIn - https://www.linkedin.com/company/aging/ Pinterest - https://www.pinterest.com/AgingUS/ Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc MEDIA@IMPACTJOURNALS.COM

Are seed oils harming your health? In today's episode of the NTI PodTalk, we are shedding some light on a topic that has a lot of conflicting information around it. Listen in as Dr. Chris Knobbe explains the critical role of industrial seed oils in contributing to chronic diseases. The discussion uncovers the pervasive presence of these oils in modern diets and their link to health issues such as cardiovascular diseases, diabetes, and Alzheimer's. Drawing on Dr. Chris Knobbe's extensive research and collaborations with nutrition experts worldwide, we examine compelling data that underscores the detrimental health impacts of seed oils. Learn how avoiding industrial seed oils and embracing a diet rooted in ancestral nutrition principles can lead to significant health benefits. About Chris: Chris Knobbe, MD, is a physician, researcher, ophthalmologist, and Associate Clinical Professor Emeritus, formerly of the University of Texas Southwestern Medical Center in Dallas, Texas. Dr. Knobbe believes his most important role today is being a public health advocate. Dr. Knobbe is known primarily for his research, publications, and presentations connecting Westernized diets causally to numerous chronic diseases, including coronary heart disease, hypertension, stroke, cancers, type 2 diabetes, metabolic syndrome, obesity, Alzheimer's disease, autoimmune diseases, and age-related macular degeneration (AMD). Dr. Knobbe's research has focused greatly on ‘vegetable oil' (seed oil) dangers and their unequaled contributions to Westernized disease. **Timestamps for the topics discussed can be found on this episode's NTI PodTalk page. Are you ready to start your journey as a Nutrition Therapist Master or Natural Food Chef? To learn more about NTI's Nutrition Therapist Master Certification, visit ntischool.com for more information, or call 303-284-8361 to speak with our admissions team. This discussion is not intended to provide Medical Nutrition Therapy, nor in any way imply that Nutrition Therapists who graduate from NTI are qualified to provide Medical Nutrition Therapy. The scope of practice for graduates of NTI is to deliver therapeutic nutrition guidance to our clients which helps support their natural biology to achieve optimal function in whatever wellness path they are on.

Just like people declutter their homes to prevent the accumulation of broken or unwanted items, cells use autophagy to maintain homeostasis. This essential cleaning process enables them to capture and degrade unnecessary or dysfunctional macromolecules, such as damaged organelles, protein aggregates, and microbial pathogens. As a result, autophagy is a fundamental defense mechanism employed by cells to control and clear viral infections. In this episode, Charlene Lancaster from The Scientist spoke with Josephine Thinwa, an assistant professor in the departments of internal medicine and microbiology at the University of Texas Southwestern Medical Center, to learn more about the importance of autophagy in mitigating viral infections and how understanding this process could help physicians treat a rare neurodevelopmental disorder. More on this topic: Macrophages Curtail Tuberculosis The Scientist Speaks is a podcast produced by The Scientist's Creative Services team. Our podcast is by scientists and for scientists. Once a month, we bring you the stories behind news-worthy molecular biology research.

In the summer of 2024, the National Institute of Standards and Technology (NIST) released a Hemp Plant Reference Material to help labs accurately measure the amount of THC, CBD, toxic elements and other compounds in cannabis products. It will also help producers and state regulators ensure that cannabis products are safe to use and accurately labeled. Today, we're going to talk about NIST's Hemp Plant Reference Material and about improving cannabis science with leading experts in the field of cannabis medicine. Our guests are Dr. Bryon Adinoff, president of the Doctors for Drug Policy Reform, and Dr. Leslie Mendoza Temple, former Chair of the Medical Cannabis Advisory Board for the Illinois Department of Public Health. Dr. Adinoff is an addiction psychiatrist, neuroscientist, academician, and advocate. He was appointed Clinical Professor at the University of Colorado School of Medicine following his retirement as Distinguished Professor of Alcohol and Drug Abuse Research in the Department of Psychiatry at the University of Texas Southwestern Medical Center and as a psychiatrist for 30 years with the Department of Veterans Affairs. He has published over 200 papers and book chapters on the neurobiology and treatment of addiction and is Editor-in-Chief of The American Journal of Drug and Alcohol Abuse. Dr. Temple is a Clinical Associate Professor for NorthShore University HealthSystem's Department of Family Medicine and Medical Director of the NorthShore Integrative Medicine Program. She was recently appointed as an endowed Chair of Integrative Medicine by the Owen L. Coon Foundation. She is also a Clinical Associate Professor in Family Medicine at the University of Chicago Pritzker School of Medicine. ◘ Related Content NIST's New Hemp Reference Material Will Help Ensure Accurate Cannabis Measurements https://bit.ly/3XWruef NIST Tools for Cannabis Laboratory Quality Assurance https://bit.ly/3Bq0lau ◘ Transcript https://bit.ly/3THgP4F ◘ This podcast features the song “Follow Your Dreams” (freemusicarchive.org/music/Scott_Ho…ur_Dreams_1918) by Scott Holmes, available under a Creative Commons Attribution-Noncommercial (01https://creativecommons.org/licenses/by-nc/4.0/) license. ◘ Disclaimer: The content and information shared in GW Integrative Medicine is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in GW Integrative Medicine represent the opinions of the host(s) and their guest(s). For medical advice, diagnosis, and/or treatment, please consult a medical professional.

The news of Texas covered today includes:Our Lone Star story of the day: Dr. Merrill Matthews joins us to talk about the 2024 presidential election and we work from several of his columns that have recently appeared in The Hill, including: For Democrats, ‘Freedom' is Just Another Word for Mandate Are You Ready for ‘Kamalanomics?' What ‘Evangelicals for Harris' Gets Terribly Wrong Merrill Matthews, Ph.D., is a health policy expert and regular columnist at The Hill. He has worked with the Institute for Policy Innovation, a research-based, public policy “think tank” in the Metroplex for many years.Dr. Matthews is a past president of the Health Economics Roundtable for the National Association for Business Economics, the largest trade association of business economists. Dr. Matthews also served for 10 years as the medical ethicist for the University of Texas Southwestern Medical Center's Institutional Review Board for Human Experimentation, co-author of On the Edge: America Faces the Entitlements Cliff, and has contributed chapters to several books, including Physician Assisted Suicide: Expanding the Debate and The 21st Century Health Care Leader and Stop Paying the Crooks (on Medicare fraud).  He has been published in numerous journals and newspapers, including The Wall Street Journal, Investor's Business Daily, Barron's, USA Today, The Hill, Forbes magazine and the Washington Times. He was an award-winning political analyst for the USA Radio Network.  Dr. Matthews received his Ph.D. in Humanities from the University of Texas at Dallas.Our Lone Star story of the day is sponsored by Allied Compliance Services providing the best service in DOT, business and personal drug and alcohol testing since 1995.Listen on the radio, or station stream, at 5pm Central. Click for our radio and streaming affiliates.www.PrattonTexas.com

In this episode of Run with Fitpage, we have Dr Joseph Watso with us to speak about the heart. Dr Joe discusses lifestyle factors that affect the cardiovascular system and alot more with our host, Vikas Singh. Dr. Joseph Watso is an Assistant Professor and the Director of the Cardiovascular & Applied Physiology (CAP) Laboratory at Florida State University in the Department of Health, Nutrition, and Food Sciences. With a focus on cardiovascular health and physiology, Dr. Watso leads research aimed at understanding and preventing cardiovascular disease, particularly in clinical populations such as those with obesity, hypertension, and older adults. His work also explores strategies to mitigate the impact of environmental stressors, like heatwaves, on heart and blood vessel health. Dr. Watso's research journey began as an undergraduate at Salisbury University's Laboratory for Human Performance (2013-2015). He later completed graduate research in the Cardiovascular Physiology Laboratory at the University of Delaware (2015-2019), where he examined the effects of high dietary salt and dehydration on blood pressure regulation during exercise. As a postdoctoral fellow at the University of Texas Southwestern Medical Center (2019-2022), he led studies on how pain medications impact the nervous system, heart, and blood vessels, and contributed to research on cooling strategies for vulnerable populations.Passionate about science communication, Dr. Watso also writes to make cutting-edge health research accessible to the public. His mission is to bridge the gap between academic science and practical health advice, empowering people to better understand and improve their cardiovascular health. The long-term goal of the CAP Lab is to advance prevention and treatment strategies for cardiovascular disease and improve public health outcomes. Dr. Watso's commitment to cardiovascular health research and public education continues to shape his work, ensuring his contributions have a lasting impact both in academia and beyond.Follow Dr Joe's work at www.caplaboratory.comAbout Vikas Singh:Vikas Singh, an MBA from Chicago Booth, worked at Goldman Sachs, Morgan Stanley, APGlobale, and Reliance before coming up with the idea of democratizing fitness knowledge and helping beginners get on a fitness journey. Vikas is an avid long-distance runner, building fitpage to help people learn, train, and move better.For more information on Vikas, or to leave any feedback and requests, you can reach out to him via the channels below:Instagram: @vikas_singhhLinkedIn: Vikas SinghTwitter: @vikashsingh101Subscribe To Our Newsletter For Weekly Nuggets of Knowledge!

In this episode of AGE BETTER with Barbara Hannah Grufferman, I dive into a groundbreaking conversation about heart health with one of the world's leading experts on cholesterol and heart disease prevention, Dr. Ann Marie Navar. Dr. Navar is an Associate Professor of Medicine and preventive cardiologist at the University of Texas Southwestern Medical Center, with a research focus on preventing heart disease through cholesterol management. She also serves on the Executive Committee of the American Society of Preventive Cardiology.    KEY TAKEAWAYS:    Understanding ApoB: Dr. Navar explains what ApoB is and why it's a more accurate marker for assessing heart disease risk than traditional cholesterol measurements like LDL-C.    Why ApoB Testing Matters: Learn why measuring ApoB can provide a clearer picture of your heart disease risk, especially if you have metabolic risk factors like obesity, diabetes, or high triglycerides, or even if you appear metabolically healthy.    Current Guidelines and Future Recommendations: Dr. Navar discusses the limitations of the current guidelines that focus primarily on LDL-C and the need to revise these guidelines to include routine ApoB testing for a more comprehensive assessment of heart health.    The Role of Coronary Artery Calcium Score: Discover the importance of the coronary artery calcium score test in evaluating plaque buildup in the arteries and how it can complement ApoB testing for a more thorough evaluation of cardiovascular risk.    Join us for this essential discussion to learn how to take proactive steps in managing your heart health with the latest insights from cutting-edge research.    KEY LINKS:  Learn more about Dr. Ann Marie Navar here.   Read more about Dr. Navar's research on ApoB here.    Get more insights in the Coronary Artery Calcium Score Test here.   More information about lipoprotein (a) here.     Don't forget to subscribe to AGE BETTER with Barbara Hannah Grufferman for more expert advice on how to age better!  Learn more about your ad choices. Visit megaphone.fm/adchoices

In this Leveling Up Episode of the PRS Global Open Deep Cuts Podcast, Dr. John Semple discusses his unusual pathway into medicine, three dimensional thinking, prepectoral breast reconstruction, the use of allograft and synthetic meshes, fat grafting in radiated breasts, some tips to make fat harvest easier, how to be a good mentor and a good leader, and how he got involved in climate science. Read a recent classic PRS Global Open article by Dr. Semple and co-authors, “Patient Outcomes after Fat Grafting to the Radiated Chest Wall before Delayed Two-stage Alloplastic Breast Reconstruction”: https://bit.ly/SempleFatGrafting  Dr. John Semple is a Professor in the Department of Surgery at the University of Toronto, and the head of the division of plastic surgery at Women's College Hospital. He is also an adjunct faculty member at the wilderness Medicine Program at Mass General Hospital in Boston, and an adjunct professor at the Ontario College of Art and Design, where was a former chair of the Board of Governors. He trained in art at OCAD and became a fully trained medical illustrator, then went into medicine, training in plastic surgery at the University of Toronto and then completing a microsurgery fellowship at the Toronto General Hospital. He is a past president of the Canadian Society of Plastic Surgeons, and received the Lavina Lickley Lifetime achievement award form the department of surgery at the University of Toronto. He also has a keen interest in mountaineering - and has been to Everest North Col 4 times, and has published numerous papers on the effects of climate change in the Himalayas.  Your host, Dr. Puru Nagarkar, is a board-certified plastic and hand surgeon, and Assistant Professor of Surgery at the University of Texas Southwestern Medical Center in Dallas. #PRSGlobalOpen #DeepCutsPodcast #PlasticSurgery #LevelingUp

Dean's Chat hosts Drs. Jeffrey Jensen and Johana Richey are joined by Dr. Lawrence Lavery, a world authority in researching the Diabetic Foot, and a member of the International Working Group on the Diabetic Foot. Today's discussion is fascinating, as we delve into the mindset, idea generation, priorities, personality and inquisitiveness that have enabled Dr. Lavery, over the past 30 years, to be a world expert in researching the diabetic foot.   Lawrence A. Lavery is transitioning to a new role to enhance his incredible research career, A former Professor in the Department of Plastic Surgery, as well as Director of Clinical Research, at the University of Texas Southwestern Medical Center, he is now moving to the University of Texas, San Antonio.  His research group has published 320 peer reviewed papers and has received extramural funding from the Veterans Administration, National Institute of Health, Agency for Healthcare Research and Quality, American Diabetes Association, and the American College of Foot and Ankle Surgeons.     Dr. Lavery's H-Index is 108.  This means that Dr. Lavery has 108 publications that have each been sited over 108 times in other peer reviewed papers. To put this into perspective, Nobel prize winners have H-Indexes of less than 70!  Wow!  Enjoy!   https://iwgdfguidelines.org/lavery/ https://deanschat.com/ https://bakodx.com/ https://bmef.org/ www.explorepodmed.org

Welcome back to the podcast! In today's must-listen episode, Chantel got to speak with Chris Knobbe   Dr. Knobbe is clinical associate professor emeritus at the University of Texas Southwestern Medical Center in Dallas. He practiced general ophthalmology from 1994 to 2015 and remained on the active volunteer faculty at the University of Texas Southwestern Medical Center from 2001 to 2015, before retiring from active practice.   Enjoy!   Heart and Soil: Website: http://chantelrayway.com/liver  Use Coupon Code: Chantelray10   Today's Episode Is Sponsored By BiOptimizers Masszymes: http://masszymes.com/waistawayfree    Use code waistaway10 for a special discount!   Today's Episode Is Sponsored By BiOptimizers Magnesium Breakthrough: Visit https://magbreakthrough.com/waistaway and enter code waistaway for 10% off any order. https://magbreakthrough.com/rf_special?rfsn=7678975.73fd57&utm_source=refersion&utm_medium=affiliate&utm_campaign=7678975.73fd57     Masszymes - https://bioptimizers.com/shop/products/masszymes?rfsn=7678975.73fd57&utm_source=refersion&utm_medium=affiliate&utm_campaign=7678975.73fd57   HCL (Hydrochloric Acid) - https://bioptimizers.com/shop/products/hcl-breakthrough?rfsn=7678975.73fd57&utm_source=refersion&utm_medium=affiliate&utm_campaign=7678975.73fd57     Sleep Breakthrough - https://bioptimizers.com/shop/products/sleep-breakthrough?rfsn=7678975.73fd57&utm_source=refersion&utm_medium=affiliate&utm_campaign=7678975.73fd57    Join Our Non-Toxic Family MasterClass: Website: https://nontoxicfamily.com/masterclass/ Join Our Facebook Group: https://www.facebook.com/groups/TheChantelRayWay/   Order One Meal And A Tasting: https://chantelrayway.com/onemeal/    Order All The Books: Waist Away: The Chantel Ray Way - 2nd Edition:  https://www.amazon.com/gp/product/0999823116/ref=dbs_a_def_rwt_hsch_vapi_tpbk_p1_i0    Fasting to Freedom: The Gift of Fasting: https://www.amazon.com/Fasting-Freedom-Gift-Chantel-Ray/dp/0999823132/ref=tmm_pap_swatch_0?_encoding=UTF8&qid=&sr=    Freedom From Food: A Six Week Bible Study Course: https://www.amazon.com/Freedom-Food-Bible-Study-Course/dp/0999823159/ref=pd_bxgy_img_3/135-7722513-4171815?_encoding=UTF8&pd_rd_i=0999823159&pd_rd_r=91d59435-2126-4f9d-867e-00646964e3e4&pd_rd_w=mg3U0&pd_rd_wg=FcVwL&pf_rd_p=fd3ebcd0-c1a2-44cf-aba2-bbf4810b3732&pf_rd_r=NWM3687GJSRKKQ4BYQP4&psc=1&refRID=NWM3687GJSRKKQ4BYQP4    Connect With Us:   Leave us a review: https://chantelrayway.com/review/    Share YOUR Story: https://chantelrayway.com/contact/   Contact directly through email at questions@chantelrayway.com    Enjoy refreshing, all-natural wine: https://chantelrayway.com/wine/   Listen to the new audiobook as a podcast HERE: https://chantelrayway.com/purchase-audio-book/   Free Video Preview: https://chantelrayway.com/top-12-thin-eater-tips-free-video/   Check out the VIDEO COURSE here: https://chantelrayway.com/video-course/   Purchase on Amazon Here: https://www.amazon.com/shop/intermittentfastingthechantelrayway   Strengthen your immune system with Vitamin C: https://chantelrayway.com/vitaminc/    Enjoy a FREE smoothie recipe book: https://chantelrayway.com/freerecipe/   Re-energize with nutritious algae Energybits: https://chantelrayway.com/energybits    Castor Oil: https://chantelrayway.com/castoroil   Connect with us on Social Media:   YouTube Channel Link: https://www.youtube.com/channel/UCteFjiVaY6n0SOAixcyZbWA   Like us on Facebook at https://www.facebook.com/TheChantelRayWay       Things we love: https://chantelrayway.com/things-i-love-2/   Facebook group: https://www.facebook.com/groups/TheChantelRayWay   ***As always, this podcast is not designed to diagnose, treat, prevent or cure any condition and is for information purposes only. Please consult with your healthcare professional before making any changes to your current lifestyle.***

If you have questions or concern about your childrens' screen time, this is the episode for you. I'm joined by pediatrician and clinical researcher Dr. John Hutton, and we dive into health concerns regarding digital media use in children, impacts on caregiver-child connection, brain development and alternatives to digital media. Dr. Hutton is an Associate Professor, Division of General & Community Pediatrics at University of Texas Southwestern Medical Center and Attending Physician, Children's Health, Dallas. Dr. Hutton is also an author of over 40 children's books. I especially loved the Baby Unplugged series which you can browse here. Dr. Hutton's published research This episode is sponsored by Bark Technologies. Learn about the Bark App for iPhones and Androids: *Use code SCROLLING2DEATH FOR 10% OFF Check out the Bark Phone --- Support this podcast: https://podcasters.spotify.com/pod/show/scrolling2death/support

Audible Bleeding contributor and 5th year general surgery resident Richa Kalsi (@KalsiMD) is joined by first-year vascular surgery fellow Zach Mattay (@ZMatthay), fifth-year general surgery resident Naveed Rahman (@naveedrahmanmd), JVS editor Dr. Thomas Forbes (@TL_Forbes), and JVS-CIT editor Dr. Matthew Smeds (@mattsmeds) to discuss two great articles in the JVS family of journals. The first article discusses national trends in surgeon-modified graft utilization for complex and thoracoabdominal aortic aneurysms. The second article discusses a novel technique, transcatheter electrosurgical aortic septotomy, to treat chronic dissecting aortoiliac aneurysms.  This episode hosts Dr. Thomas O'Donnell (@tfxod) and Dr. Carlos Timaran (@ch_timaran), the authors of these two papers. Articles: Part 1:“National Trends in utilization of surgeon-modified grafts for complex and thoracoabdominal aortic aneurysms” by Dr. O'Donnell and colleagues. Mentioned during the discussion:  “Application of Investigational Device Exemptions regulations to endograft modification” by Abel and Farb.  Part 2: “Early results of transcatheter electrosurgical aortic septotomy for endovascular repair of chronic dissecting aortoiliac aneurysms” by Dr. Timaran and colleagues. Mentioned during discussion: “Transcatheter Electrosurgery: JACC State-of-the-Art Review” by Khan and colleagues. “A Novel Way to Fenestrate a Type B Dissection Flap Using Endovascular Electrocautery” by Dr. Kabbani and colleagues.  Show Guests  Dr. Thomas O'Donnell: Assistant professor of surgery in the aortic center at New York Presbyterian/Columbia University Irving Medical Center. Dr. Carlos Timaran: Professor and Chief of Endovascular Surgery at University of Texas Southwestern Medical Center's Department of Surgery.   Follow us @audiblebleeding Learn more about us at https://www.audiblebleeding.com/about-1/ and provide us with your feedback with our listener survey.

Dean's Chat Co-hosts, Dr. Jeffrey Jensen and Dr. Johanna Richey are joined by Dr. Paul Kim, Medical Director at the University of Texas – Southwestern Medical Center. Dr. Kim received his undergraduate degree from CU-Boulder and then went to the Kent State College of Podiatric Medicine. He completed his 3-year surgical residency at Inova Medical Center and also received a Master's Degree in Clinical Research Management. His career in academics has spanned from the Arizona College of Podiatric Medicine to Georgetown University School of Medicine prior to his UT-Southwestern position. His passion for surgery, research, and self-discovery is evident in this episode as we discuss life transitions, passion when to make a professional career move, and career fulfillment. Tune in for a fascinating conversation about podiatric medicine! Dr. Paul Kim stresses the importance of defining success for oneself and remaining open to adjusting goals as one progresses and changes. He emphasizes the need to be flexible in defining success and to adapt to new circumstances and personal growth. Dr. Kim shares his journey of setting and resetting goals throughout his career, noting how his goals and definition of success have shifted as he moved from residency to different academic centers. Dr. Kim discusses the significance of being realistic in goal-setting and understanding one's limitations. He highlights the role of mentors in helping individuals recognize both strengths and limitations, guiding them toward achievable goals. Dr. Kim and Dr. Richey discuss the concept of work-life balance and propose focusing on work-life alignment or harmony instead. Dr. Kim suggests that the pursuit of a perfect work-life balance is unrealistic and can lead to stress and anxiety. He suggests that the term "work-life balance" can create undue pressure on individuals to evenly distribute their time and energy between work and personal life. Dr. Richey adds to this by emphasizing the importance of defining success and setting goals that align with core values and bring joy to life. She notes that the journey towards success is not linear and that definitions of success may evolve over time.  The conversation between Dr. Kim and Dr. Richey highlights that work-life alignment or harmony may be a more practical and sustainable approach than striving for a perfect balance. By aligning actions with values and priorities at different life stages, individuals can adapt to shifting priorities and maintain flexibility. A wonderful discussion – Enjoy! https://explorepodmed.org/ Dean's Chat Website Dean's Chat Episodes Dean's Chat Blog Why Podiatric Medicine?  Become a Podiatric Physician https://lelandjaffedpm.com https://higherlearninghub.com  

*The award lecture and its accompanying slides are also available to watch here: https://youtu.be/fM6aPNO8MxY. The Herbert Tabor Research Award is given for outstanding, innovative accomplishments in biological chemistry and molecular biology and contributions to the community of scientists. Margaret Phillips is chair of the biochemistry department at the University of Texas Southwestern Medical Center, where her research focuses on metabolism in protozoan parasites. Her lab studies essential enzymes controlling pyrimidine biosynthesis in the parasite that causes malaria and polyamine synthesis in the trypanosome that causes sleeping sickness. Her lab has used structural-guided drug design to optimize and develop pyrimidine synthesis inhibitors with potential to become antimalarial drugs. Learn more: https://www.asbmb.org/asbmb-today/people/081623/asbmb-names-2024-award-winners.

Raeann Wilson was born in Cabot, AR. As a breast cancer survivor, IV therapy was an integral part of Raeann's recovery, and she became passionate about giving the same level of care to other post-operation patients. As the surgical coordinator at Shewmake Plastic Surgery, Raeann has extensive knowledge in surgical processes and patient care. This all gave her the skill and inspiration to create Zen Infusion, offering mobile, on-demand IV infusion therapy that serves a number of needs for the people of Central Arkansas. Kris Shewmake, M.D., FACS was born in Pine Bluff, AR. He earned his bachelor's degree in biology from Hendrix College in Conway and a master's degree in natural science from the University of Arkansas at Fayetteville. He received his medical degree from UAMS, where he also completed a residency in general surgery. He was president of his class and elected into the Alpha Omega Alpha Medical Honor Society (top 10% of the class). His eight years of surgical training after medical school included a General Surgery residency at the University of Arkansas for Medical Sciences (UAMS) Medical Center and a Plastic and Reconstructive Surgery residency in Dallas at the University of Texas-Southwestern Medical Center. Dr. Shewmake entered private practice in 1996 and was named Best Plastic Surgeon in Arkansas by his colleagues in 1999 and 2009.

On this episode of JHLT: The Podcast, the JHLT Digital Media Editors explore two studies from the May issue of The Journal of Heart and Lung Transplantation. Digital Media Editor David Schibilsky, MD, a cardiothoracic surgeon from Freiburg, Germany, hosts this episode.   First, Dr. Schibilsky and Digital Media Editor Erika Lease, MD, interview their first guest, Helen A. Hannan, the podcast's first-ever undergraduate pre-medical guest, from the University of Michigan. Helen was the lead author on the study “Racial and Gender Disparities in Transplantation of Hepatitis C+ Hearts and Lungs.” The study noted that prior research in utilization of kidneys from donors with Hepatitis C had shown disparities due to gender and education—and wanted to see if this was the case in heart and lung donors as well.   Drs. Schibilsky and Lease chat with Helen about the findings of the study, including some of the interesting differences shown between heart and lung recipients, and the ramifications for better patient discussions at the clinical level.   Next, Dr. Schibilsky and Digital Media Editor Marty Tam, MD, interview their next guest, Lauren Truby, MD, of the University of Texas Southwestern Medical Center in Dallas. Dr. Truby is the podcast's first return guest, having appeared on the show near the end of 2021. This time, she's featured as first author on the study “Metabolomic profiling during ex situ normothermic perfusion before heart transplantation defines patterns of substrate utilization and correlates with markers of allograft injury.” The paper explores cardiac metabolism of donor hearts during recovery using an ex situ normothermic perfusion system (NRP).   Dr. Truby provides an in depth look at the project's logistics—which she calls a “labor of love”—its multi-point findings, and what's next in this line of research.   Follow along at www.jhltonline.org/current, or, if you're an ISHLT member, access your Journal membership at www.ishlt.org/jhlt.   Don't already get the Journal and want to read along? Join the International Society of Heart and Lung Transplantation at www.ishlt.org for a free subscription, or subscribe today at www.jhltonline.org.    

Doctors James Ferriss, Linda Duska, and Jayanthi Lea discuss the promise and the challenges of targeting the immune system with immune checkpoint inhibitors, or ICIs, in cervical and endometrial cancers. They also examine emerging data that support the use of ICIs in recurrent cervical cancer, the potential for curing some patients with advanced endometrial cancer, and molecular factors that make cervical cancer a good target for immunotherapy. TRANSCRIPT Dr. James Stuart Ferriss: Hello, and welcome to the ASCO Daily News Podcast. I'm Dr. James Stuart Ferriss, your guest host of the ASCO Daily News Podcast today. I'm an associate professor of gynecology and obstetrics and the Gynecologic Oncology Fellowship Program Director at Johns Hopkins Medicine. In today's episode, we'll be discussing the use of immunotherapy in cervical and endometrial cancers to advance the treatment of these malignancies. I'm delighted to be joined by two acclaimed experts in this space, Dr. Linda Duska and Dr. Jaya Lea.   Dr. Duska is a professor of obstetrics and gynecology and serves as the associate dean for clinical research at the University of Virginia School of Medicine. Dr. Lea is a professor of obstetrics and gynecology and chief of gynecologic oncology at the University of Texas Southwestern Medical Center.  Our full disclosures are available in the transcript of this episode, and disclosures related to all episodes of the podcast are available at asco.org/DNpod. Drs. Duska and Dr. Lea, it's great to have you on the podcast today.  Dr. Linda Duska: Thanks, Dr. Ferriss.  Dr. Jayanthi Lea: Thanks, Dr. Ferriss.  Dr. James Stuart Ferriss: So, let's get started. In recent years, we've had a revolution in the treatment of advanced endometrial and cervical cancers with improved outcomes for patients treated with immunotherapy. And when we say immunotherapy, we're specifically talking about immune checkpoint inhibitors today. A few of these agents have actually been approved in the United States for the management of these diseases. In our discussion, I'd like to review the promise and challenges of targeting the immune system in patients with advanced endometrial and cervical cancers, as well as review the most recent evidence we have in these spaces.  Let's start with cervix. We've had a lot of improvements in outcomes here, Dr. Lea, and with cervical cancer, we've seen improved overall survival with the incorporation of immunotherapy along with chemotherapy and anti-angiogenic therapy for advanced and recurrent disease. Can you remind us why cervical cancer is a good target for immunotherapy?  Dr. Jayanthi Lea: Yes, Dr. Ferriss. Immunotherapy for cervical cancer is supported by several molecular factors. And I think first and foremost, it's so important to remember that the majority of cervical cancers are HPV-positive. And HPV-positive cancers can induce a high level of inflammation, but this high level of inflammation actually contributes to evasion of immune surveillance. What it also does is that it's responsible for the induction of PD-L1. And we've seen several studies that have shown that cervical cancers express PD-L1 anywhere from 50 to 90 percent of cases. Other pertinent factors to consider are that cervical cancer can be considered a tumor with a high tumor mutational burden. So, the number of somatic mutations that we see in the DNA can be considered as a proxy for neoantigens. And so the higher the level of neoantigens, the more immunogenic the tumor. And then lastly, about 1 in 10 cervical cancers present with microsatellite instability, which is an already established key biomarker for the response team in care.  Dr. James Stuart Ferriss: So, thinking about targeting PD-L1, what clinical evidence do we have that supports the use of immune checkpoint inhibitors in recurrent cervical cancer?  Dr. Jayanthi Lea: We now have several studies that have shown a benefit for immune checkpoint inhibitors. For example, KEYNOTE-158 was a phase 2 basket [trial] that investigated the antitumor activity of pembrolizumab, which is a PD-1 inhibitor, in multiple cancer types. And specifically for patients with previously treated advanced cervical cancer, we were able to see an overall response rate of about 15% in those patients who had PD-L1 positive. And similarly, the EMPOWER CERVICAL-1 study, which was a phase 3 randomized trial that investigated the efficacy of cemiplimab, which is another PD-1 inhibitor, versus investigator's choice of single agent chemotherapy, showed a significant difference in median overall survival and progression-free survival in the cemiplimab group. There are several other studies that have investigated the efficacy of PD-1 or PD-L1 inhibitors in cervical cancer. One specific PD-1 inhibitor is nivolumab. In CHECKMATE-358, nivolumab was associated with an overall response rate of 26% in women who had recurrent/metastatic cervical cancer.  Dr. James Stuart Ferriss: Dr. Duska, do you have any thoughts?  Dr. Linda Duska: I'm really interested in PD-L1 as a biomarker because in the KEYNOTE-A18 study, which we're going to get to, 95% of patients were PD-L1 positive by CPS, which is the scoring system that we use in cervix cancer. And some of the studies that you already mentioned, including BEATcc, which we're also going to talk about, reported results where PD-L1 wasn't even considered. And so it begs the question, since PD-L1 is actually – again, depending on when in the course of disease you look at it, but more recent studies suggest 95% of cervical cancers express PD-L1, and – agnostic is the word I was looking for – it seems at least in BEATcc and similar trials that PD-L1 is agnostic, but I wonder if PD-L1 is really a good biomarker for response to checkpoint inhibitor therapy and I wonder what your thoughts are.  Dr. Jayanthi Lea: I think that's an excellent question. To your point, that's correct that we saw in KETYNOTE-A18 that more than 90% of the patients had PD-L1 positivity and the result is sort of generalizable to all comers. That's still a matter of debate as to how we see PD-L1 as a biomarker to incorporate checkpoint inhibitors in the treatment of patients.  Dr. James Stuart Ferriss: So, let's talk about the use of immune checkpoint inhibitors in the frontline setting. Until recently, we haven't seen much improvement in overall survival since the introduction of anti-angiogenic therapy to the chemotherapy backbone, and that was in GOG 240. Let's talk about the changes that have recently occurred in this space.  Dr. Jayanthi Lea: So, we've had some very exciting data specifically from initially KEYNOTE-826 and its primary metastatic or first line salvage settings. So, KEYNOTE-826, which was a phase 3 randomized, controlled trial was very practice-changing for us because it showed that incorporation of pembrolizumab to the first-line treatment of patients with metastatic or recurrent cervical cancer, really changed the landscape for treatment in this group of patients. So, keep in mind that prior to the study, the standard of care was carboplatin, or cisplatin with paclitaxel plus or minus bevacizumab, which yielded a median overall survival range in anywhere from 13 to 17 months depending on whether you use bevacizumab or not. And then adding pembrolizumab to that regimen, increase the median overall survival to 24 months, which is very promising.  Dr. James Stuart Ferriss: If I remember correctly, KEYNOTE-826 allowed investigators choice, use of bevacizumab, and initially we were unsure about which regimen was best. Has there been additional data since?  Dr. Jayanthi Lea: There has been additional data since. And another study that was done in the same vein was the BEATcc trial, which also looked at the different checkpoint inhibitors, atezolizumab in combination now with bevacizumab and platinum-based chemotherapy. And the control arm for this study was the GOG 240 regimen, which included bevacizumab. And this study showed both a progression-free and overall survival difference. The median overall survival in this study was 32 months with the incorporation of the checkpoint inhibitor to the bevacizumab and platinum-based chemotherapy. So, the way that I look at it is that the BEATcc trial basically confirmed the findings of KEYNOTE-826 and highlights that it is important for us to incorporate checkpoint inhibition with immunotherapy along with bevacizumab when we're treating patients with a recurrence.  Dr. James Stuart Ferriss: Also, folks with primary advanced treatment for cervical cancer, this would be a great regimen, is that right?  Dr. Jayanthi Lea: Absolutely. Primary advance, we would want to use the same regimen for that.  Dr. James Stuart Ferriss: Okay. What about locally advanced in primary treatment? What advances have we seen?  Dr. Jayanthi Lea: So we've had some major changes in that field as well, especially with the recent KEYNOTE-A18 data where pembrolizumab was administered in combination with external beam radiation and concurrent chemotherapy. And this study showed that there was significant and clinically meaningful improvement in progression-free survival compared to chemoradiation alone. Specifically, the progression-free survival at 24 months using pembrolizumab with chemoradiation was 68%, and 57% when in the placebo group. The hazard ratio for disease progression was 0.7 and no new safety signals were observed, which is fantastic, especially given the 0.7 hazard ratio that received PFS.  Dr. James Stuart Ferriss: Yeah, absolutely. These patients with locally advanced cervical cancer often are quite symptomatic, and the prospect of adding chemo, radiation, and now immunotherapy on top of that is really encouraging to see that it was such a well-tolerated regimen. I believe that there were patient-reported outcomes recently reported at SGO.  Dr. Jayanthi Lea: Absolutely. So, the safety profile of pembrolizumab and chemoradiation was consistent with the known profile of the individual treatment components. And no new safety signals emerged in the pembrolizumab chemoradiation arm. So, you're right. It was very well tolerated.  Dr. James Stuart Ferriss: What would you say are the takeaways for folks who are seeing these patients in the community? These locally advanced cervical cancer patients that are now adding immunotherapy in a space that we have not used routinely in the past in terms of combining it with chemo radiation in gynecologic cancer. What are some things they should be looking out for?  Dr. Jayanthi Lea: Well, I think that with the hazard ratio of 0.7 and the patient-reported outcomes showing no new signal, I think we can say that there is a positive benefit-to-risk profile of adding pembrolizumab in combination with chemoradiation, and that we should feel comfortable using this regimen. Now, of course, we have individualized patient care, and be able to know when to use bevacizumab, when to use immunotherapy. So, taking the whole patient into consideration becomes important. But for those individuals who are able to receive these drugs who don't have concrete issues to not receive these drugs [then I'd say we could] incorporate them since the safety profile is set.  Dr. Linda Duska: I would add to that, Dr. Ferriss, that right now we only have FDA approval in the U.S. for stage 3-4A disease, and that's 2014 staging. Mind you, we are now in 2018, so we should be very careful in and follow the correct FIGO staging. But the FDA only gave approval for stage 3-4A disease, even though the study included patients with earlier stage disease and positive nodes.  Dr. James Stuart Ferriss: That's a great point, thank you.  So, Dr. Duska, thinking about endometrial cancer and advanced endometrial cancer, we have seen a similar revolution in the care of patients over the past few years, with major shifts in our approach. Can you remind us how we got here?  Dr. Linda Duska: Yes, I would say in the ‘90s and before, and maybe even in the early 2000s, we used a lot of radiation for endometrial cancer as adjuvant therapy following surgery. The general consensus and what we were all taught was that this was a chemotherapy-resistant disease. And then we learned from a variety of GOG at the time, Gynecologic Oncology Group trials, that this disease is actually chemosensitive. And we went through a series of chemotherapy drugs, ranging from adriamycin cisplatin to taxel adriamycin cisplatin, and finally to taxel and carboplatin, demonstrating that this disease is actually quite chemosensitive.  With this realization came the idea that maybe it would be important to combine chemotherapy and radiation particularly in high-risk endometrial cancer cases, so those with positive nodes or patients with high-risk histology such as clear cell or serous cancers. So two very important trials were done, one of them was PORTEC-3 and the other was GOG-258, which looked at combining chemo and radiation together to see if we could do better than one or the other alone. And they were very different trials, and they looked at different populations of patients and they looked at different things. For example, PORTEC-3 randomized patients to receive chemotherapy and radiation versus radiation alone, while 258 looked at chemotherapy and radiation versus chemotherapy alone. Without going into a great amount of detail, I think what we learned from both of those studies, and I think surprised many of us, that the arms that included chemotherapy, those patients did better.  In fact, the results of GOG-258 can be interpreted – and this is somewhat controversial – but can be interpreted that many of these high-risk patients don't need radiation at all, or perhaps need tumor-directed radiation. For example, chemotherapy followed by tumor-directed radiation either to the vaginal cuff, because the vaginal cuff is at risk for recurrence, or perhaps to an area of concern, maybe the cervix if there were cervical involvement or if there is a particular concern for local recurrence in a particular patient. So, I think the pendulum has swung from almost always using radiation alone to, in more modern day, using chemotherapy and using radiation much more sparingly, and then comes immunotherapy.  Dr. James Stuart Ferriss: So, update us on the results of NRG-GY018 and RUBY?  Dr. Linda Duska: So, we've already talked about the KEYNOTE basket trials, which really contributed a lot to our understanding of the importance of MMR deficiency and microsatellite unstable disease. The KEYNOTE-158 study and the GARNET study showed us how important it was for women with MMRd and MSI endometrial cancer to receive checkpoint inhibition, and actually with remarkable response rates to women who had already been pretreated. But we also learned from the GARNET trial, which included MMRp patients, that the response rates in MMRp were not that great. And that led to KEYNOTE-775, which looked to combine pembrolizumab with a VEGF inhibitor, lenvantinib, to see if we could make the cold tumor hot. And indeed, we could. And not only could we improve the response rate in patients with MMRp tumors, but we could also improve the response rate in patients with MMRd tumors. They did better with the combination than they did with pembro alone.  That led to the idea of combining checkpoint inhibitors with chemo upfront. The idea there was we were going to take paclitaxel and carboplatin, which were our backbone for advanced or recurrent endometrial cancer, and add immunotherapy to that. And to your point, GY018 and RUBY trials did just that. And they allowed MMRd and MMRp patients and combined paclitaxel and carboplatin, either with dostarlimab in the case of RUBY, or pembrolizumab in the case of GY018. These studies, both of which were reported and published in the New England Journal of Medicine last year, showed remarkable findings in the upfront setting and potentially in the curable setting. And the OS data for RUBY were presented at SGO this year and were remarkable for MMRd patients. In the whole population, in the whole group in RUBY, there was a 16.4-month improvement in overall survival with the addition of dostarlimab which is just huge.  When you look at the MMRd group, I think Dr. Powell described the overall survival improvement as unprecedented. I believe that was the word that he used. Also, he called it very robust, with a hazard ratio of 0.32 for the group that got dostarlimab, and a median OS that was not reached. So really remarkable. In addition, in the MMRp group, there was a seven-month improvement in OS that was significant. So that's really amazing in the RUBY trial. It's also of note that the RUBY trial allowed carcinosarcomas, whereas the GY018 study did not. So, I think it's fair to say that these results apply to carcinosarcomas.  It's also really important to note that many of the patients in the immunotherapy group who received placebo, 41% of them got IO in a later treatment line, and these OS data still stand. So that's really interesting and hypothesis-generating. For GY018, we don't have mature OS data yet, so we can't talk about OS. But we saw a similar improvement in PFS in both arms, in the d and the pMMR, with an OS trend in both arms that was also reported at SGO. GY018 was a little bit different though, because they unblinded at the time of the PFS reporting last year, and so those patients were unblinded a lot earlier than the RUBY patients were. So, to interpret the data in that vein, the OS data is not mature, but we anticipate looking at the PFS curves and the preliminary OS curves, that the OS data will also be statistically significantly improved in core pembrolizumab in GY018.  What's also really interesting, and we haven't talked about molecular subtypes, is that when we look at the molecular subtypes in RUBY, and I'm sure we're going to see data on the molecular subtypes in GY018 coming up, different molecular subtypes of endometrial cancer respond differently to IO. And so, there's going to be lots of really interesting data coming our way soon that we're really excited to see, and that will help us triage patients appropriately into treatment regimens.  Dr. James Stuart Ferriss: Dr. Lea, did you have a thought?  Dr. Jayanthi Lea: Yeah, I just wanted to comment that looking at the dMMR survival curve in the file that was presented recently, one thing that really strikes me is the importance of adding the IO at the time of initial treatment. The separation of the curves persists. And, like you just mentioned, Dr. Duska, I mean, some of those patients who received placebo then later on went to get an IO treatment, but at the same time, we still see a vast separation of those curves. So, I think it's really important to note that immunotherapy should be used upfront, especially in dMMR.  Dr. Linda Duska: Yeah, I completely agree with that. And I think that might be– I mean, this is just a hypothesis, but I think that that might be why we saw a difference with the addition of immunotherapy in the MMRp group, because it's possible that the chemotherapy created an immune environment that made the checkpoint inhibitor work more successfully than it would have otherwise. So, a really good point. You definitely need to include dostarlimab or pembrolizumab with the chemotherapy and then as maintenance therapy after.  Dr. James Stuart Ferriss: So, you mentioned, we're increasingly thinking about endometrial cancer in smaller and smaller buckets of patients with very prescribed molecular profiles. We don't yet have enough information to specifically tailor treatment. How are you approaching that today in patients that you see in clinic?  Dr. Linda Duska: Well, the MMR, and I'm interested in what you both are doing also, it's easy with the MMRd and MSI high patients. Those patients all should receive a checkpoint inhibitor, no question. The patients that are p53 mut, I test them for HER2, because we do have data to suggest that atezolizumab or TDX-d might be useful in those individuals, HER2 positive. And then the remaining patients, also called the NSMPs. That's a difficult group. I'm interested to know how you all manage them. I think that's the group where more clinical research is really needed to determine what the best treatment regimen for them is. But I'm interested in both of your thoughts on that.  Dr. James Stuart Ferriss: Dr. Lea?  Dr. Jayanthi Lea: I would have to say that I do exactly like you do, Dr. Duska.  Dr. James Stuart Ferriss: And I would say our approach is very similar. And we have a robust discussion always about the use of immunotherapy with chemotherapy and in patients who are proficient MMR. But I think that most of us believe that the PFS data is certainly compelling. And now the OS data from RUBY, very compelling in both groups. And so, we are routinely recommending the use of immunotherapy along with chemotherapy in these advanced patients.  Dr. Linda Duska: I've heard the argument made that GY018 required measurable disease, and so does not necessarily apply to patients without measurable disease. I'm not sure that I agree with that. I think there were clinical trial reasons why that was a requirement rather than biologic reasons. In addition, as we already discussed, RUBY included carcinosarcomas and GY018 did not. I don't think there's a reason to only use dostarlimab for carcinosarcomas, but that said, I don't know that pembrolizumab has an indication for carcinosarcomas. The devil's in the details, don't get too lost in the weeds. I think the take-home message here is that it's really important to use IO, particularly for the MMRd patients with endometrial cancer, upfront. And based on the OS that we saw in both RUBY and preliminarily in GY018, we may be curing some people with this regimen, and I think we should focus on that. The overall survival for advanced endometrial cancer is not great, and if we can improve that and potentially cure some people, that's a huge advance for our patients.  Dr. James Stuart Ferriss: Do you envision a day that we might even ask the question, “Do we need to do surgery?”  Dr. Linda Duska: So, the rectal data would support that assertion. I'm not sure that endometrial cancer and rectal cancer are the same thing. And I think that taking out a postmenopausal woman's uterus is a lot less morbid than potentially radiating or taking out somebody's rectum. I think a different question would be, is there a day when we would stop doing no dissection? We could definitely debate that, but I don't see that happening. Do you see that happening anytime soon? A stopping of hysterectomy for endometrial cancer? Dr. Jayanthi Lea: I don't see that happening anytime soon. And I think, as you said, taking out the uterus, tubes, and ovaries, it does provide us with some information about whether you're even dealing with a secondary primary. But also, it's from a quality-of-life standpoint. If a woman has a large uterus, that's uncomfortable. Postmenopausal bleeding, avoiding bleeding during the course of treatment, so many reasons why I wouldn't be in too much of a hurry to want to not do surgery for these patients. Dr. James Stuart Ferriss: So, we'll put a plug in for our fellow gynecologic oncologists that we still have a role to play in the incorporation of treatment regimens for patients with advanced uterine cancer. So it's not just medicine, there's still a role for surgery.  Dr. Linda Duska: I think that's very fair, yeah. Dr. James Stuart Ferriss: Okay. I think that's all the time we have for today.  I want to thank our listeners for their time, and you'll find the links to all the studies we've discussed today in the transcript of this episode. And finally, if you value the insights that you hear on the ASCO Daily News Podcast, please take a moment to rate, review, and subscribe wherever you get your podcasts. Thank you.  Dr. Linda Duska: Thank you. Dr. Jayanthi Lea: Thank you. Disclaimer: The purpose of this podcast is to educate and to inform. This is not a substitute for professional medical care, and is not intended for use in the diagnosis or treatment of individual conditions. Guests on this podcast express their own opinions, experience, and conclusions. Guest statements on the podcast do not express the opinions of ASCO. The mention of any product, service, organization, activity, or therapy should not be construed as an ASCO endorsement.    Find out more about today's speakers: Dr. James Stuart Ferriss Dr. Linda Duska @LDuska Dr. Jayanthi Lea   Follow ASCO on social media:  @ASCO on Twitter  ASCO on Facebook  ASCO on LinkedIn    Disclosures: Dr. James Stuart Ferriss: Honoraria: National Board of Medical Examiners Dr. Linda Duska: Consulting or Advisory Role: Regeneron, Inovio Pharmaceuticals, Merck, Ellipses Pharma Researching Funding (Inst): GlaxoSmithKline, Millenium, Bristol-Myers Squibb, Aeterna Zentaris, Novartis, Abbvie, Tesaro, Cerulean Pharma, Aduro Biotech, Advaxis, Syndax, Pfizer, Merck, Genentech/Roche, Cerulean Pharma, Ludwig Institute for Cancer Research, Leap Therapeutics Patents, Royalties, Other Intellectual Property: UpToDate, Editor, British Journal of Ob/Gyn Dr. Jayanthi Lea: Consulting or Advisory Role: Roche

In this episode, Lillian Erdahl, MD, FACS is joined by Dai Chung, MD, FACS, from the University of Texas Southwestern Medical Center. They discuss Dr Chung's recent study, which demonstrates that poor health outcomes among pediatric solid tumor patients are associated with minority race and residence in rural or border regions, and that the 5-year rate mortality rises with increasing area deprivation score.   Disclosure Information: Drs Erdahl and Chung have nothing to disclose.   To earn 0.25 AMA PRA Category 1 Credits™ for this episode of the JACS Operative Word Podcast, click here to register for the course and complete the evaluation. Listeners can earn CME credit for this podcast for up to 2 years after the original air date.   Learn more about the Journal of the American College of Surgeons, a monthly peer-reviewed journal publishing original contributions on all aspects of surgery, including scientific articles, collective reviews, experimental investigations, and more.   #JACSOperativeWord

Dr. Rena Malik is an accomplished urologist specializing in Female Pelvic Medicine and Reconstructive Surgery (Urogynecology). She completed her medical schooling at New York University School of Medicine, followed by urologic residency at the University of Chicago and a fellowship at the University of Texas Southwestern Medical Center. Currently, she serves as an Associate Professor of Surgery in the Division of Urology and as the Director of Female Pelvic Medicine and Reconstructive Surgery at the University of Maryland School of Medicine.She is also actively involved in medical education through her YouTube channel, "Rena Malik, M.D.," which has amassed over 1.9 million subscribers.In this episode we cover:- Ways to boost testosterone naturally, and its broad impacts on health and vitality.- Common myths around sexual phenomena, clarifying their normalcy and health implications.- The role of health literacy and its importance in post-surgical care and overall health outcomes.- Causes of sexual dysfunction, both psychological and physiological factors affecting men and women.- Practical advice for enhancing sexual health and intimacy, including effective communication strategies and lifestyle tips.Sponsors for this episode: Bon Charge- Use code NEURO for 15% off - https://boncharge.com/collections/red-light-therapy-devices?rfsn=7851803.209b11Inside Tracker - Use code LOUISA20 for 20% off - https://insidetracker.com/louisaConnect with Dr. Rena Malik: Instagram: instagram.com/renamalikmdYouTube: https://www.youtube.com/@RenaMalikMD(00:00) Preview and Introduction(01:51) Dr. Rena Malik's Background(05:54) Debunking Sexual Health Myths(09:49) Impact of Testosterone on Men and Women(13:19) Testosterone Deficiency Epidemic: Causes and Solutions(16:15) How To Boost Testosterone(21:56) Stigmas Around Sexual Arousal (25:52) Does Size Really Matter?(28:27) Addressing Sexual Dysfunction In Men and Women(31:15) Root Causes for Low Sexual Desire (36:43) How To Improve Sexual Relationships(37:58) Link bw Ejaculation and Prostate Cancer(40:35) Dr. Rena Malik's Tips for Better Sexual HealthThe Neuro Athletics Newsletter Instagram: @louisanicola_Twitter : @louisanicola_YouTube: @Louisa NicolaThe Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner.

Save 20% on all Nuzest Products WORLDWIDE with the code MIKKIPEDIA at www.nuzest.co.nz, www.nuzest.com.au or www.nuzest.comThis week on the podcast Mikki speaks to Dr Jose Antonio about protein, caffeine, myths in sport science and nutrition, and his hot take on protein for endurance athletes.Jose Antonio earned his PhD and completed a postdoctoral research fellowship at the University of Texas Southwestern Medical Center in Dallas. He's the CEO and co-founder of the International Society of Sports Nutrition as well as the co-founder of the Society for Sports Neuroscience. He is a Professor in Exercise and Sport Science at Nova Southeastern University in Davie Florida. His research agenda includes work on high-protein diets, sports neuroscience, and sports supplements. He is also an author of 15 books and over 180 peer-reviewed publications.Jose https://healthsciences.nova.edu/faculty/human-performance/antonio-jose.htmlPaper https://healthsciences.nova.edu/faculty/human-performance/antonio-jose.htmlResearch gate: https://www.researchgate.net/profile/Jose-Antonio-22/2 ISSN link: https://www.sportsnutritionsociety.org/Sport Science Dudes https://podcasts.apple.com/us/podcast/sports-science-dudes/id1670156526  Contact Mikki:https://mikkiwilliden.com/https://www.facebook.com/mikkiwillidennutritionhttps://www.instagram.com/mikkiwilliden/https://linktr.ee/mikkiwillidenCurranz supplement: MIKKI saves you 25% at www.curranz.co.nz or www.curranz.co.uk off your first order

Estás escuchando #JUNTOSRadio ¿Qué enfermedades cardiacas son más comunes en la comunidad latina?, ¿Qué medicamentos o sustancias pueden alterar mi ritmo cardiaco?, El Dr. Rigoberto Ramírez, Profesor Asistente de Medicina en el Departamento de Medicina Cardiovascular del Centro Médico de la Universidad de Kansas, nos responde a estas y otras preguntas.       Sobre nuestro invitado:   El Dr. Rigoberto Ramírez obtuvo su título de médico en 2011 en el Centro Médico de la Universidad de Kansas. Su programa de residencia en medicina interna se completó en 2014 en la Universidad de Texas Southwestern Medical Center. A partir de ahí, completó una beca en enfermedades cardiovasculares en junio de 2017, además de una beca en electrofisiología en 2019 en el St. Luke's Hospital de Kansas City. Tras su formación, se incorporó al Centro Médico de la Universidad de Kansas en 2019.      Recursos informativos en español:    U.S. Department of Health and Human Services (HHS)   https://health.gov/espanol/myhealthfinder/problemas-salud/salud-corazon/manten-sano-tu-corazon  National Heart, Lung, and Blood Institute (NIH)   https://www.nhlbi.nih.gov/es/salud/vida-cardiosaludable     Facebook: @juntosKS      Instagram: juntos_ks      YouTube: Juntos KS   Twitter: @juntosKS      Página web: http://juntosks.org      Suscríbete en cualquiera de nuestras plataformas de Podcast: Podbean, Spotify, Amazon Music y Apple Podcast - Juntos Radio      Centro JUNTOS Para Mejorar La Salud Latina      4125 Rainbow Blvd. M.S. 1076,      Kansas City, KS 66160     No tenemos los derechos de autor de la música que aparece en este video. Todos los derechos de la música pertenecen a sus respectivos creadores.   

The NACE Journal Club with Dr. Neil Skolnik, provides review and analysis of recently published journal articles important to the practice of primary care medicine. In this episode Dr. Skolnik and guests review the following publications:1. Aspirin and Cardiovascular Risk in Individuals With Elevated Lipoprotein(a) Guest:Brad Rivotto, MDResident – Family Medicine Residency ProgramJefferson Health – Abington 2. Triple – Hormone-Receptor Agonist Retatrutide for Obesity — A Phase 2 TrialJulio Rosenstock, MDSenior Scientific Advisor for Velocity Clinical Research,Director of Velocity's site at Medical City Dallas,Clinical Professor of Medicine at the University of Texas Southwestern Medical Center, Dallas.3. Healthy weight loss maintenance with exercise, GLP-1 receptor agonist, or both combined followed by one year without treatment: a post-treatment analysis of a randomised placebo-controlled trial.Amrin Syed, DO Resident – Family Medicine Residency Program Jefferson Health – AbingtonMedical Director and Host, Neil Skolnik, MD, is an academic family physician who sees patients and teaches residents and medical students as professor of Family and Community Medicine at the Sidney Kimmel Medical College, Thomas Jefferson University and Associate Director, Family Medicine Residency Program at Abington Jefferson Health in Pennsylvania. Dr. Skolnik graduated from Emory University School of Medicine in Atlanta, Georgia, and did his residency training at Thomas Jefferson University Hospital in Philadelphia, PA. This Podcast Episode does not offer CME/CE Credit. Please visit http://naceonline.com to engage in more live and on demand CME/CE content.Please visit http://naceonline.com to engage in more live and on demand CME/CE content.

In this episode, Dr. Ashleigh Halderman, Rhinologist and Associate Professor at the University of Texas Southwestern Medical Center, discusses chronic invasive fungal sinusitis with hosts Dr. Gopi Shah and Dr. Ashley Agan, First, Dr. Halderman outlines her advocacy work as President of the Texas Association of Otolaryngology. Then, the discussion transitions to chronic invasive fungal sinusitis. Dr. Halderman defines the disease, describes typical patient presentation, and reviews concerning imaging findings. Until biopsy can clinch the diagnosis, she maintains a high index of suspicion in cases of bizarre clinical presentation or facial paresthesia. The surgeons then shift their attention to management, which consists of culture-directed antifungals and judicious surgical intervention. Dr. Halderman wraps up the episode by sharing her pearls for operative management and long-term surveillance. --- SHOW NOTES 00:00 - Introduction 02:10 - Exploring the Texas Association of Otolaryngology 05:58 - Understanding Chronic Invasive Fungal Sinusitis: Types & Treatments 20:25 - Diagnostic Challenges and Imaging Insights 27:07 - Navigating Diagnostic Challenges and Treatment Options 29:40 - The Role of Biopsy in Confirming Fungal Infections 30:52 - Surgical Considerations and Pre-Operative Strategies 40:29 - Surveillance Strategies: Managing Chronic Invasive Fungal Sinusitis 46:34 - The Future of Surgical & Antifungal Therapies for Chronic Invasive Fungal Sinusitis --- RESOURCES Dr. Ashleigh Halderman's UT Southwestern Profile: https://utswmed.org/doctors/ashleigh-halderman/ BackTable ENT Episode 30, “Revision Endoscopic Sinus Surgery" https://www.backtable.com/shows/ent/podcasts/30/revision-endoscopic-sinus-surgery Texas Association of Otolarynogology: https://www.taohns.org/

Host Maureen A. Madden, DNP, RN, CPNP-AC, CCRN, FCCM, FAAN, is joined by Dr. Lakshmi Raman, MD, to explore critical insights into pediatric ECMO, addressing neurological complications and their potential mitigation strategies and other topics associate with the article "Early Changes in Arterial Partial Pressure of Carbon Dioxide and Blood Pressure After Starting Extracorporeal Membrane Oxygenation in Children: Extracorporeal Life Support Organization Database Study of Neurologic Complications" (Pedtr Crit Care Med. July 2023; 24(7):541-550). Dr. Raman is Professor of Pediatrics and Medical Director of ECMO at the University of Texas Southwestern Medical Center and Children's Medical Center in Dallas, Texas.

For this episode of “Ask the Expert: Research Edition,” "Increased Intracranial Pressure in Pediatric MOG Antibody Disease," Krissy Dilger of SRNA was joined by Dr. Cynthia Wang and Dr. Linda Nguyen. They discussed MOG antibody disease and the significance of MOG antibodies in diagnosis (00:00:02-00:03:36). Dr. Nguyen highlighted the background of the study and how this research focused on determining the impact of elevated intracranial pressure on patient outcomes (00:03:52-00:06:56). She reviewed the implications of the findings for patient management, emphasizing the importance of early recognition and intervention to mitigate disability (00:10:34-00:14:02). Dr. Wang and Dr. Nguyen anticipated future studies and stressed the collaborative effort required for better patient outcomes and the need for ongoing research in this field (00:17:16-00:20:30). Dr. Linda Nguyen completed her MD, PhD training at West Virgina University in 2017, and then pediatric neurology residency at University of California San Diego in 2022. Currently, she is a neuroimmunology fellow at University of Texas Southwestern. Dr. Cynthia Wang received her medical degree from University of Texas Southwestern Medical Center in Dallas, Texas and completed a pediatrics and pediatric neurology residency at Mott Children's Hospital, University of Michigan Health System in Ann Arbor, Michigan. Dr. Wang completed her James T. Lubin Fellowship under the mentorship of Dr. Benjamin Greenberg at The University of Texas Southwestern and Children's Health. Her research study was a prospective, longitudinal study on acute disseminated encephalomyelitis (ADEM) to identify the clinical characteristics, treatment methods, and follow-up interventions that are associated with better and worse patient-centered outcomes.

Feedback or suggestions for this retirement podcast?  Leave a voice message here Today's Building Block: Wellness What does an emotionally intelligent retirement look like? In this 4th edition of the Retirement Roundtable, two of our favorite previous guests, Kate Schroeder & Nick Wignall, return to discuss the questions to ask yourself now to be well prepared for the emotional aspects of the transition to retirement. ________________________ Bios Kate Schroeder is a psychotherapist in private practice. She is a Licensed Professional Counselor, Nationally Certified Counselor, and owner of Transformation Counseling, LLC. With over 25 years in the mental health field, her clinical background includes experience as a school counselor, mental health therapist in an urban university's counseling center, individual, couples, group, and family therapist, and clinical researcher. Within these settings, Kate has provided individual, group and family counseling for clients experiencing difficulties in areas including depression and anxiety, adjustment and transitional concerns, C-PTSD, acculturation and multicultural issues, family and childhood conflicts, interpersonal relationships, grief and trauma, eating disorders, LGBTQ issues, self-efficacy, career exploration and various other interpersonal conflicts. Kate also holds certification as a massage therapist, physical trainer and physical education teacher. In addition to her private practice, she also teaches graduate courses to counselors in training. Kate joins us again from St Louis. Nick Wignall is a licensed clinical psychologist who is Board-certified in behavioral and cognitive psychology. He's the founder of the popular newsletter, The Friendly Mind, with practical, evidence-based advice for emotional health and wellbeing. The newsletter is read by 50,000+ people each week and his writing has been featured in media outlets like NBC, Business Insider, Inc Magazine, Aeon and Medium. Nick is the author of Find Your Therapy: A Practical Guide to Finding Quality Therapy, .a guide to learning about the most important factors in choosing a therapist and how to go about finding a good one, either for yourself or someone you love. He did his doctoral training in clinical psychology at the University of Texas Southwestern Medical Center in Dallas, including research in human genetics and psychopharmacology. Prior to that, Nick earned his Masters in Social Sciences from the University of Chicago and a bachelor's in English Literature from the University of Dallas. Nick joins us again form Albuquerque, New Mexico. _________________________ For More on Kate Schroder & Nick Wignall Kate Schroeder Nick Wignall First Visits to the Podcast: The Emotional Side of Retiring – Kate Schroeder Coping Strategies & Moving Forward – Nick Wignall & Verla Fortier __________________________ Retiring? Check our recommendations on the Best Books About Retirement __________________________ Mentioned in This Podcast Episode Source: Our World in Data   Who do we spend time with across our lifetime? ____________________________ Podcast Episodes You May Like The Self-Healing Mind – Gregory Scott Brown, M.D. The Portfolio Life – Christina Wallace Chatter & Your Inner Voice – Ethan Kross Edit Your Life – Elisabeth Sharp McKetta ____________________________ Other Retirement Roundtable podcast episodes Michelle Pannor Silver Ted Kaufman, and Bruce Hiland  Fritz Gilbert, Dr. Barbara O'Neill, and Mark Shaiken Melissa Davey, Richard Haiduck and Thelma Reese ____________________________ Wise Quotes from This Retirement Roundtable On Exploring Who You Are "So much research out there now shows that adjusting to retirement has its own set of difficulty and challenges for many, many people, especially for a lot of people who've identified a lot with their work and they've gotten a lot of accolades and self-este...

CardioNerds Dr. Rick Ferraro (cardiology fellow at Johns Hopkins Hospital) and Dr. Eunice Dugan (cardiology fellow at the Cleveland Clinic) join episode lead Dr. Tiffany Brazile (cardiology fellow at the University of Texas Southwestern Medical Center and postdoctoral fellow at the Institute for Exercise and Environmental Medicine) to discuss the impact of obesity on cardiovascular disease risk, differential risk in specific populations, and effective strategies for counseling patients. They are joined by expert Dr. Jaime Almandoz, Medical Director of the Weight Wellness Program and an Associate Professor of Medicine at the University of Texas Southwestern Medical Center. Audio editing was performed by CardioNerds Academy Intern, student Dr. Tina Reddy. This episode was produced in collaboration with the American Society of Preventive Cardiology (ASPC) with independent medical education grant support from Novo Nordisk. See below for continuing medical education credit. Claim CME for this episode HERE. CardioNerds Prevention PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls and Quotes - Obesity & Cardiovascular Disease Risk The durability of metabolically healthy obesity (i.e., normal A1c, lipids, LFTs, BMP, normotensive) is limited. Within 5 years, a third of adults with “metabolically healthy” obesity will develop a cardiometabolic complication. The biomechanical and psychosocial complications of obesity are just as important as the cardiometabolic complications. Biomechanical and psychosocial complications, including obstructive sleep apnea, joint pain, and mood disorders also influence cardiovascular disease risk. Weight loss is not always the patient's goal. Meet patients where they are and understand their challenges, concerns, and long-term goals with respect to their cardiovascular health and obesity. This information provides an opportunity to frame the conversation in a supportive and engaging way that allows for patient education. Body mass index (BMI) is a screening tool for obesity, but is not sufficient for providing individualized care. Obesity management methods that result in rapid weight loss may not be appropriate for all patients. These methods, such as bariatric surgery and GLP1-receptor agonists, require regular monitoring, follow-up, and multidisciplinary care (e.g., nutritionist, exercise physiologist, endocrinologist, cardiologist, psychologist, etc.). Show notes - Obesity & Cardiovascular Disease Risk Is it possible to be healthy at any size? Whether an individual can be healthy at any size depends on the definition of health and its durability.Approximately 10-15% of adults with obesity are metabolically healthy.The risk for developing cardiometabolic disease is higher in obese versus non-obese adults. One in three adults with metabolically healthy obesity will develop cardiometabolic complications (i.e., insulin resistance/diabetes, hyperlipidemia, hypertension) within five years. Thus, metabolically healthy obesity may represent a transient phenotype with adverse long-term consequences. Consider non-metabolic health consequences of obesity that also influence cardiovascular disease risk. Obstructive sleep apnea, joint pain leading to decreased physical activity, and mood disorders are key considerations here and encompass the biomechanical and psychosocial consequences of obesity. Does large, rapid weight loss result in poorer long-term weight loss than slower, gradual weight loss? When approaches to weight loss are not sustainable, such as extremely low-calorie diets or extreme fitness regimens, the results and associated health benefits are less likely to be durable. Rapid, large-magnitude weight loss is appropriate for some adults with obesity and can be achieved throug...

We sit down with Dr. Jose Antonio, the cofounder of the International Society of Sports Nutrition, researcher, and professor to talk about various aspects of dietary protein intake.  Our discussion includes: The origin story of the International Society for Sports Nutrition (ISSN) and its mission Some of his research findings in trained athletes who followed various high protein diets The role of protein in body composition change and in the aging process Links: Some of Dr. Antonio's research studies in protein include: https://pubmed.ncbi.nlm.nih.gov/26778925/ https://pubmed.ncbi.nlm.nih.gov/24834017/ https://pubmed.ncbi.nlm.nih.gov/30244609/ https://pubmed.ncbi.nlm.nih.gov/27807480/ The International Society of Sports Nutrition More about our guest:   Dr. Antonio is Chief Executive Officer and Co-founder of the International Society of Sports Nutrition, an academic nonprofit dedicated to the science and application of sports nutrition and supplementation. In addition, he is the Co-founder and Vice President of the Society for Neurosports, an academic nonprofit with a focus on sports neuroscience. Dr. Antonio earned his PhD and completed a post-doctoral research fellowship at the University of Texas Southwestern Medical Center in Dallas. He has published over 100 peer-reviewed papers as well as 15 books. His current areas of research include: dietary supplements (e.g., creatine, protein, etc.), sports neuroscience and human performance. He is currently a Professor at the Nova Southeastern University in Davie, Florida and serves on the Advisory Board of Forbes Health. Check out his podcast, the Sports Science Dudes, with his co-host Tony Ricci EdD. The Sports Science Dudes can be found on YouTube and Spotify. Twitter @JoseAntonioPhD --- This episode is brought to you by All Around Snack Co. which features tasty snacks that are low in added sugars, contain zero dyes, colorings or additives and help control blood sugar for steady energy levels throughout the day.  Use code ISNPODCAST24 to save 15% on your purchase. We'd love to connect with you on social! Follow the podcast on Instagram @isnpodcast, and you can follow Dina at @nutritionmechanic and Bob at @enrgperformance. You can learn more about Bob and Dina's nutrition and coaching services and programs at www.enrgperformance.com and www.nutritionmechanic.com. 

Dr. Chris Knobbe is a returning guest on our show! Be sure to check out his first appearance on episode 73 of Boundless Body Radio, and also his latest appearance on episode 459 on our show!  Suzanne Alexander is also a returning guest on our show, appearing in episode 541 of Boundless Body Radio! Chris Knobbe, MD is an ophthalmologist and Associate Clinical Professor Emeritus, formerly of the University of Texas Southwestern Medical Center, in Dallas, Texas. Dr. Knobbe has a deep interest in general nutrition and seed oils, particularly as they relates to chronic degenerative disease, though his primary area of expertise is with the disorder age-related macular degeneration, aka AMD, which is the leading cause of irreversible vision loss and blindness in people over the age of 65. Suzanne Alexander, M.Ed., is a multi-award-winning educator with over 30 years of experience in the classroom and a highly accomplished health and nutrition researcher with over 40 years of research to her credit.Dr. Knobbe's research efforts and revolutionary hypothesis for the nutritional basis of AMD have resulted in published scientific papers, his first book titled Ancestral Dietary Strategy to Prevent and Treat Macular Degeneration, and the website CureAMD.org, a nonprofit organization dedicated to the prevention of vision loss from AMD. His latest book, written with Suzanne, is titled The Ancestral Diet Revolution: How Vegetable Oils and Processed Foods Destroy Our Health- and How to Recover!Find Dr. Knobbe and Suzanne at-IG- @ancestoralhealthfoundationAmazon- The Ancestorial Diet Revolutionhttps://www.cureamd.org/YT- @chrisknobbemdFind Boundless Body at- myboundlessbody.com Book a session with us here!

In this episode, Dr. Ashley Agan and Dr. Gopi Shah cover in-office laryngology procedures with Dr. Lesley Childs, Associate Professor of Laryngology, Neuro-Laryngology, and Professional Voice at the University of Texas Southwestern Medical Center. The surgeons cover laryngologic diseases commonly treated in the clinic. Dr. Childs describes procedures she performs, including video stroboscopy for mucosal wave assessment, steroid injections for subglottic stenosis, and Botox injections for neurologic voice disorders. She also speaks to the benefits of treating patients in-office, anesthesia for in-office procedures, and the role her medical assistants play during various in-office procedures. --- EARN CME Reflect on how this Podcast applies to your day-to-day and earn free AMA PRA Category 1 CMEs: https://earnc.me/GrOWrn --- SHOW NOTES 00:00 Introduction 02:58 In-Office Laryngology Procedures Overview 03:49 Understanding Video Stroboscopy 05:27 Preparing for In-Office Procedures 08:09 Procedure Techniques and Patient Positioning 13:40 Anesthetic Protocol for Different Procedures 15:11 Handling Patient Reactions and Complications 26:11 Botox Injections and Anesthetic Considerations 29:08 Understanding False Vocal Folds and Abraham Cannula 35:01 Understanding the Process of Vocal Fold Botox Injections 36:06 The Risks and Challenges of Vocal Fold Injections 40:41 The Process of Vocal Fold Augmentation 52:33 The Use of Lasers in Vocal Fold Procedures 53:40 The Evolution of Vocal Fold Procedures Over Time

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Former Oklahoma police officer Nate Tarver recounts his law enforcement career path from the 1970s to present. He begins as the first Black officer in Moore, OK facing racism. Later he joined the Oklahoma City force, rising in rank and mentoring others who became high-ranking officers. Tarver shares how he created a school liaison program and taught DARE, influencing youth like Rob Allen who later credited Tarver for impacting his career. Tarver becomes Deputy Chief at the University of Oklahoma before accepting the Chief of Police role at University of Texas Southwestern Medical Center in Dallas. Throughout his career, Tarver values mentoring other officers and seeing the positive impact he made on people's lives.

In this episode, hosts Drs. Jennifer Lee and Jason Silverman talk to Dr. Norberto Rodriguez-Baez about Hepatitis B. We discuss diagnosis, treatment options, and the importance of vaccinations to prevent transmission of this virus.Dr. Rodriguez-Baez is a professor of pediatrics at University of Texas Southwestern Medical Center and hepatologist at Children's Health in Dallas, Texas. He is program director of the pediatric GI fellowship at UT Southwestern and associate Dean for Student Affairs. He is the NAPSGHAN 2022 awardee for the Master Educator Award.This episode is eligible for CME credit!  Once you have listened to the episode, click this link to claim your credit.  Credit is available to NASPGHAN members (if you are not a member, you should probably sign up).  And thank you to the NASPGHAN Professional Education Committee for their review!Learning Objectives:Outline hepatitis B serologic markers, diagnosis, phases, and treatmentReview importance of primary vaccination series in hepatitis BUnderstand when to test for immunity and consider re-vaccination against hepatitis BSupport the showMerch website As always, the discussion, views, and recommendations in this podcast are the sole responsibility of the hosts and guests and are subject to change over time with advances in the field.Follow us on Twitter, Facebook and Instagram for all the latest news and upcoming episodes! Support the show As always, the discussion, views, and recommendations in this podcast are the sole responsibility of the hosts and guests and are subject to change over time with advances in the field.Follow us on Twitter, Facebook and Instagram for all the latest news and upcoming episodes!

Is your child acting entitled and selfish? Are you worried they are showing signs of narcissism? Some warning signs can include constantly wanting to be the center of attention, never compromising, and continually insisting that things can only be their way.  However, as a parent, how can you tell the difference between a budding narcissist and a child throwing a tantrum? After all, healthy children push boundaries and act out as part of typical development. Join us as our guest, renowned early childhood narcissism expert Dr. Mary Ann Little, explains the difference between usual childhood behavior and potential warning signs. To learn more -- or read the transcript -- please visit the official episode page. Our guest, Mary Ann Little, PhD, is a clinical psychologist who has been in private practice for over four decades. She is currently an adjunct professor at the University of Texas Southwestern Medical Center at Dallas and has served as an adjunct professor in the departments of psychology and special education at the University of Texas at Dallas. Dr. Little authored Loving Your Children Better: Matching Parenting Styles to the Age and Stage of Your Children; Cooperation Station, an educational toy for kids and families; and the Competent Kids Series. Her latest book, Childhood Narcissism: Strategies to Raise Unselfish, Unentitled, and Empathetic Children, is out now. Dr. Little has been a consultant to numerous educational and psychiatric facilities and frequently lectures to both lay and professional audiences. When not in her Dallas office, she can be found with her husband cooking, cycling back roads in Europe, or hiking trails near Santa Fe. Visit her online at drmaryannlittle.com. Our host, Gabe Howard, is an award-winning writer and speaker who lives with bipolar disorder. He is the author of the popular book, "Mental Illness is an Asshole and other Observations," available from Amazon; signed copies are also available directly from the author. Gabe makes his home in the suburbs of Columbus, Ohio. He lives with his supportive wife, Kendall, and a Miniature Schnauzer dog that he never wanted, but now can't imagine life without. To book Gabe for your next event or learn more about him, please visit gabehoward.com. Learn more about your ad choices. Visit megaphone.fm/adchoices

Chris Knobbe, MD, is a physician, researcher, ophthalmologist, public health advocate, and Associate Clinical Professor Emeritus, formerly of the University of Texas Southwestern Medical Center in Dallas, Texas.  Dr. Knobbe is known primarily for his research, publications, and presentations connecting Westernized diets and highly polyunsaturated vegetable oils to numerous chronic diseases, including coronary heart disease, hypertension, stroke, cancers, type 2 diabetes, metabolic syndrome, obesity, Alzheimer's disease, autoimmune diseases, and age-related macular degeneration (AMD).  Dr. Knobbe's research has focused greatly on the “vegetable oil hypothesis” as the primary driver of overweight and chronic disease.  In 2016, Knobbe formally introduced the hypothesis that processed foods and vegetable oils are the primary drivers of AMD, which is the leading cause of irreversible vision loss and blindness in people over the age of 50, worldwide.   GET THE MEAT: http://NosetoTail.org FREE SAPIEN FOOD GUIDE: http://sapien.org   SHOW NOTES (3:06) Dr. Chris Knobbe's latest publication: Ancestral Diet Revolution (4:54) How Dr. Knobbe left his ophthalmologist practice in 2015 to pursue the topic of seed oils (6:10) The connection between age-related macular degeneration and diet (12:06) Dr. Chris Knobbes impactful use of data and graphs (14:43) Why are seed oils more concerning than other processed foods? (41:31) Dietary changes in populations across the globe and prevalence of disease- the modern displacement of foods (1:04:49) The effect of sugar vs. vegetable oils on the rate of incidence in the United States (1:18:30): Dietary lipid profile is a determinant of tissue phospholipid fatty acid composition and rate of weight gain in rats (https://pubmed.ncbi.nlm.nih.gov/8463854/) (1:26:40) Seeds oils and poor diet as a driver for cancer (1:34:23) Diet and lifestyle is crucial in determining health outcomes regardless of genetics   GET THE MEAT: http://NosetoTail.org FREE SAPIEN FOOD GUIDE: http://sapien.org   Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg        

Dr. Cynthia Li is a leading expert in ecosystem medicine, Qigong, efficient healing, and intuition, and in this episode, she shares with you the journey to optimal health. Dr. Li takes you on a guided tour of the many facets of optimal health, from food and lifestyle choices to physical and emotional health.  Purchase Brave New Medicine: https://amzn.to/3UX3G55 (Amazon Link) What I Discuss with Dr. Cynthia Li About Intuitive Healing Are you looking for an alternative to traditional medical treatments? Do you want to explore more holistic approaches to health and well-being? If so, you'll want to listen to this interview. Dr. Cynthia Li received her medical degree from the University of Texas Southwestern Medical Center in Dallas. She's practiced as an internist in many settings, including Kaiser Permanente Medical Center, San Francisco General Hospital, and St. Anthony Medical Clinic serving the homeless. She currently has a private practice in Berkeley, CA, and recently published her first book, Brave New Medicine: A Doctor's Unconventional Path to Healing Her Autoimmune Illness. Full show notes and resources can be found here: https://passionstruck.com/dr-cynthia-li-on-intuitive-healing-using-qigong/  Brought to you by MasterClass, Omaha Steaks, and POM Wonderful. --► For information about advertisers and promo codes, go to: https://passionstruck.com/deals/  --► Prefer to watch this interview: https://youtu.be/kQp6Phdoh1c  Like this show? Please leave us a review here -- even one sentence helps! Consider including your Twitter or Instagram handle so we can thank you personally! --► Subscribe to Our YouTube Channel Here: https://www.youtube.com/c/JohnRMiles Want to find your purpose in life? I provide my six simple steps to achieving it - passionstruck.com/5-simple-steps-to-find-your-passion-in-life/ Did you miss my interview with NYU Stern School marketing professor Scott Galloway? Listen to episode 218 on why America is adrift and how to fix it. ===== FOLLOW ON THE SOCIALS ===== * Instagram: https://www.instagram.com/passion_struck_podcast * Gear: https://www.zazzle.com/store/passion_sruck_podcast Learn more about John: https://johnrmiles.com/