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Today's show:*Working from 9 am to 9 pm, 6 days a week, might seem like TOO INTENSE a commitment for some, but Jason argues that elite performance — and the mega-compensation that goes along with it — sometimes requires personal sacrifice. While 72-hour weeks might lead to burnout for some, it really comes down to individual choice.PLUS Jason and Alex deep dive the NBA gambling scandal and the sketchy reality behind high-stakes home games of poker. PLUS Presh Kumar takes us behind the scenes, to see how AI apps helped him develop and workshop the video for his new wellness startup, Tempo, and what's with Anthropic buying chips from their AI rivals, Google? It's a can't miss This Week in Startups.Timestamps:(00:06:49) Jason and Alex are poker fans… what do they think about this insane NBA gambling scandal?(10:00) LinkedIn Ads - Start converting your B2B audience into high quality leads today. Launch your first campaign and get $250 FREE when you spend at least $250. Go to http://LinkedIn.com/ThisWeekinStartups to claim your credit.(20:00) Nexos.ai - Stop Shadow AI in its tracks with the unified platform for secure AI adoption and productivity. Try it with a free 14-day trial at https://nexos.ai/twist.(00:25:09) Is working “9-9-6” a reasonable goal? A guarantee of success? Why Jason compares it to being an Olympian.(30:00) Every.io - Running a startup is hard enough. Every takes care of incorporation, banking, payroll, benefits, accounting, taxes and more so that you focus on building, not back-office admin. Visit every.io.(00:38:00) Our old buddy Presh walks us through the process of making his Tempo launch video(00:42:28) Jason and Alex check out some of Ridley Scott's famous storyboards(00:48:03) Anthropic is buying TPUs from Google… Are these companies in LIKE with each other?Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:LinkedIn Ads - Start converting your B2B audience into high quality leads today. Launch your first campaign and get $250 FREE when you spend at least $250. Go to http://LinkedIn.com/ThisWeekinStartups to claim your credit.Nexos.ai - Stop Shadow AI in its tracks with the unified platform for secure AI adoption and productivity. Try it with a free 14-day trial at https://nexos.ai/twist.**Every.io -** Running a startup is hard enough. Every takes care of incorporation, banking, payroll, benefits, accounting, taxes and more so that you focus on building, not back-office admin. Visit every.io.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
Is the stock market in an AI bubble? What happens if it bursts? To understand our current economic moment, it's essential to understand history. That's why journalist and author Andrew Ross Sorkin joined host Jeff Berman onstage at the Masters of Scale Summit in San Francisco in October. His new book is 1929: Inside the Greatest Crash in Wall Street History–and How It Shattered a Nation. Sorkin explains the lessons we can learn from this historical moment – and how they provide cautionary tales.The book: https://www.penguinrandomhouse.com/books/665634/1929-by-andrew-ross-sorkin/Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today's show:*Amazon's dropping a LOT of employees for AI and robots… are Jason's darkest predictions coming true?Legendary investor Elad Gil joins Jason and Alex for the full show today! Together, they're digging into the Amazon news, looking back at Jason's predictions from just last month, and theorizing about just how many people will lose their jobs to computers, and what we're going to do about it. (Is it possible the US hasn't been massively hit by job displacement so far because those gigs already moved overseas?)PLUS… Anthropic's Dario Amodei responds to criticisms from JCal's bestie David Sacks, Sesame emerges from stealth to work on AI wearables, and where will people in the future interact with their favorite apps? A headset? Phones? Somewhere else? The great debate continues.Timestamps:(00:04:04) Our guest is iconic angel investor Elad Gil! What's he working on…(00:04:54) Alexandria AI translates public domain books into all commonly spoken languages… Do people actually prefer AI translations?(00:09:16) Why compute tends to centralize over time… (It's because of economies of scale!)(00:09:29) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(00:12:49) So are we building TOO MANY datacenters? Will AI apps eventually run on your phone anyway?(00:16:39) Jason says “The Age of Efficiency is upon us.”(00:19:24) When companies trade inference for market share(00:19:27) Sentry - New users get 3 months free of the Business plan (covers 150k errors). Go to http://sentry.io/twist and use code TWIST(00:21:57) Why one of the main challenges of adopting AI is buy-in and convincing teams to use it.(00:25:47) Elad's robotics questions: (1) What % of winners will be incumbents?(00:27:50) Jason called the Amazon news last month and we have the receipts!(00:29:36) Pilot - Visit https://www.pilot.com/twist and get $1,200 off your first yea(00:45:33) Jason says Adobe and Figma should abandon the UK entirely.(00:45:55) Time for a Polymarket: The sharps say 80% chance Tesla beats their quarterly earnings(00:51:02) What is Sesame? They just emerged from stealth, they raised $250M, and they're working on AI wearables.(00:53:21) Jason has concerns about AI wearables that are always recording… Does Elad share these concerns?(01:03:17) The crypto industry is now one of the largest purchasers of US government debt… what does that mean? Who owns who?(01:08:53) Anthropic responded to JCal's Bestie David Sacks… Is Dario Amodei a doomer? Fearmongering?(01:19:12) Why Jason thinks AI companies need to self-regulateSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWISTSentry - New users get 3 months free of the Business plan (covers 150k errors). Go to http://sentry.io/twist and use code TWISTPilot - Visit https://www.pilot.com/twist and get $1,200 off your first yeaGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
Are AI tools in the classroom just time-savers, or can they have genuine educational value?In a must-watch TWiST 500 interview, Alex chats with Magic School founder (and former principal) Adeel Khan about how AI tools can make teachers more effective, and keep students inspired, without just doing all the work for them. He talks about turning an AI chatbot into a true assistant teacher, that keeps the lessons balanced yet challenging, and particularly empowers classroom novices and non-professionals.THEN… is 6 years too long for employees to wait to vest? Is this just another founder trying to reinvent EVERYTHING, just because they can't resist? Ramp CEO Eric Glyman joins Jason and Alex to answer pressing founder questions from viewersPLUS there's a new entrant in our Gamma Pitch Deck competition, and it's so compelling, Jason can't wait to invest! Kris Canete of On the Fly Energy tells us about America's fragile power grid and his elegant solution: flywheel energy storage!Timestamps:0:00 - Welcome to TWiST!02:59 - Former principal Adeel Khan of TWiST 500's Magic School AI tells us why “teachers are magic”09:41 - Goldbelly ships America's most delicious, iconic foods nationwide! Get 20% off your first order by going to Goldbelly.com and using the promo code TWiST at checkout.10:50 - How AI tools can particularly help out classroom novices and non-pros who are just getting started20:57 - Check out the online payroll and benefits experts with software built specifically for small business and startups. Try Gusto today and get three months FREE at Gusto.com/twist.26:58 - How Magic School stays ahead of shifting standards across different states and regions32:57 - Zite is the fastest way to build *business software* with AI. Build apps, forms, websites and portals that connect to the tools you already use. Go to *zite.com/twist* to get started.33:30 - Why the best feedback Adeel ever got came from a teenager36:30 - Making AI a true assistant teacher, that keeps lessons balanced yet challenging38:38 - Is a 6-year vesting schedule too aggressive? Eric Glyman responds.41:00 - When even ambitious founders should sometimes just accept a standard deal.57:33 - What IS flywheel energy storage?01:00:00 - Why Jason loves the Fly Energy Gamma pitch and wants to invest right now.01:34:13 - Gamma Outro*Subscribe to the TWiST500 newsletter: [https://ticker.thisweekinstartups.com](https://ticker.thisweekinstartups.com/)Check out the TWIST500: [https://www.twist500.com](https://twist500.com)Subscribe to This Week in Startups on Apple: https://rb.gy/v19fcp*Follow Lon:X: https://x.com/lons*Follow Alex:X: https://x.com/alexLinkedIn: [ / alexwilhelm ]( / alexwilhelm )*Follow Jason:X: / jason LinkedIn: [ / jasoncalacanis ]( / jasoncalacanis )Great TWIST interviews: [Will Guidara,]( • Lessons in Unreasonable Hospitality with W... ) [Eoghan McCabe]( • Great Builders & Success First with Interc... ), [Steve Huffman](https://podcasts.apple.com/us/podcast..., [Brian Chesky](https://podcasts.apple.com/ca/podcast..., [Bob Moesta,]( • Decoding Customer Insights, Trust, and the... ) [Aaron Levie](https://podcasts.apple.com/ca/podcast..., [Sophia Amoruso](https://podcasts.apple.com/ca/podcast..., [Reid Hoffman](https://podcasts.apple.com/ca/podcast..., [Frank Slootman](https://podcasts.apple.com/ca/podcast..., [Billy McFarland](https://podcasts.apple.com/ca/podcast...)*Check out Jason's suite of newsletters: https://substack.com/@calacanis*Follow TWiST:Twitter: / twistartups YouTube: / thisweekin Instagram: [ / thisweekinstartups ]( / thisweekinstartups )TikTok: / thisweekinstartups Substack: [https://twistartups.substack.com](
Can AI help us better understand animals and, if it could, what might we discover? This week's episode was recorded live at the 2025 Masters of Scale Summit where Reid and Aria sat down with Aza Raskin, co-founder and CEO of the Earth Species Project. Aza and his team are using AI to decode the languages and cultures of non-human species. From dolphins that invent new tricks together to crows that raise each other's young in communal “villages,” Aza reveals the startling complexity of animal communication and what it teaches us about our own. During the course of their conversation, Reid, Aria and Aza explore why recognizing the intelligence of the animal kingdom might spark a new Copernican Revolution, one that changes not just science, but who we believe ourselves as a species to be. It's a thought provoking journey through language, empathy, and the limits of human perspective that will make you listen to the natural world a little differently. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/ Topics: 00:00 – Live introduction from the Masters of Scale Summit 00:58 – Aza Raskin explains the Earth Species Project and its mission 03:03 – How AI can decode animal language and culture 05:18 – Crows, whales, and dolphins—evidence of communication and community 07:32 – What we've missed by only “hearing the shouts” of other species 08:30 – Dolphins learning to innovate together and what it reveals about intelligence 09:57 – Elephants' overlapping calls and the idea of “communal grammar” 12:33 – From speaking to listening: the ethics of interspecies understanding 14:23 – Names, self-awareness, and identity across dolphins, elephants, and belugas 16:05 – Animal rituals, drum languages, and AI's early attempts at conversation 18:10 – Animal Language Processing as science's next frontier 20:38 – The moral shift: what animals teach us about empathy, AI, and responsibility Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Each episode seeks to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.
From attacks by President Trump to active lawsuits against Microsoft and OpenAI, The New York Times is engaged in a fierce fight to preserve the future of independent journalism. It also keeps building a multi-faceted, excellence-obsessed brand with more users for games, recipes and podcasts than ever before. President and CEO Meredith Kopit Levien joins Bob Safian live on stage at the Masters of Scale Summit in San Francisco to explore The Times business model, how news coverage relates to the organization's fast-growing lifestyle products, and the impact of AI as a threat and a tool.Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Reid Hoffman has been at the center of every major tech shift, from co-founding LinkedIn and helping build PayPal to investing early in OpenAI. In this conversation, he looks ahead to the next transformation: how artificial intelligence will reshape work, science, and what it means to be human.In this episode, Reid joins Erik Torenberg and Alex Rampell to talk about what AI means for human progress, where Silicon Valley's blind spots lie, and why the biggest breakthroughs will come from outside the obvious productivity apps. They discuss why reasoning still limits today's AI, whether consciousness is required for true intelligence, and how to design systems that augment, not replace, people.Reid also reflects on LinkedIn's durability, the next generation of AI-native companies, and what friendship and purpose mean in an era where machines can simulate almost anything. This is a sweeping, high-level conversation at the intersection of technology, philosophy, and humanity. Resources:Follow Reid on X: x.com/reidhoffmanFollow Alex on X: x.com/arampell Stay Updated: If you enjoyed this episode, be sure to like, subscribe, and share with your friends!Find a16z on X: https://x.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zListen to the a16z Podcast on Spotify: https://open.spotify.com/show/5bC65RDvs3oxnLyqqvkUYXListen to the a16z Podcast on Apple Podcasts: https://podcasts.apple.com/us/podcast/a16z-podcast/id842818711Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.
Deel's growth overshadows SpyGate, Claude learned new skills, and the great “momentum is moat” debate | EXXXToday's show:*Deel's growing fast enough that investors are overlooking the espionage allegations and jumping on board anyway. (LAUNCH now owns a lil taste of Deel, so Jason is on board!)PLUS is the Mag 7 about to become the Mag 70… Why legendary investor Roelof Botha thinks VC is not an asset class… How startups can use capital as a weapon… AND Anthropic gave Claude more skills, which they hope will help pay their bills.Timestamps:(00:01:34) Jason's excited for ski season and checking his favorite powder app, OpenSnow(00:04:02) Why Jason's done with meetings; he's pulling a Doug Leone!(00:06:27) Jason can tell the market's heating up because people are starting to lose their minds.(00:09:31) How much will global AI tools one day be worth? Alex is crunching the numbers.(10:00) Miro - Help your teams get great done with Miro. Check out miro.com to find out how!(00:15:22) PREDICTION: The Mag7 is about to become the Mag70(20:00) Alphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at https://www.alpha-sense.com/twist(00:25:36) Deel's big raise… Why major growth overshadows spying allegations(30:00) LinkedIn Ads: Start converting your B2B audience into high quality leads today. Launch your first campaign and get $250 FREE when you spend at least $250. Go to http://LinkedIn.com/ThisWeekinStartups to claim your credit.(00:33:31) Why Roelof Botha says VC is a “return-free risk,” and not an “asset class.”(00:40:49) The two reasons why VC firms end(00:44:18) How startups can use capital as a weapon(00:57:52) Anthropic gave Claude Skills to pay the bills(01:00:51) Jason's vision for what Grammarly could becomeSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Miro - Help your teams get great done with Miro. Check out miro.com to find out how!Alphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at LinkedIn Ads: Start converting your B2B audience into high quality leads today. Launch your first campaign and get $250 FREE when you spend at least $250. Go to http://LinkedIn.com/ThisWeekinStartups to claim your credit.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
Story of the Week (DR):Blowhard CEOs:Cerebras CEO Andrew Feldman says you can't 'build something extraordinary' working 38 hours a weekSam Altman Says If Jobs Gets Wiped Out, Maybe They Weren't Even “Real Work” to Start WithMarc Benioff Says Trump Should Send Guard Troops to San FranciscoRon Conway skewers Mark Benioff in board resignation after 25 years: ‘I now barely recognize the person I have so long admired'Peter Thiel says he warned Elon Musk to ditch donating to The Giving Pledge because Bill Gates will give his wealth away ‘to left-wing nonprofits'JPMorgan CEO Jamie Dimon Says There's a 'Heightened Degree of Uncertainty'Best Buy's CEO says growing spending power gap between affluent and poor ‘keeps me up at night'Billionaire bosses like Jeff Bezos and Reid Hoffman denounce work-life balance—and some think working nonstop is key to successLogitech CEO Hanneke Faber says she would consider adding an AI agent to her board of directorsPlaid CEO says 'it's inevitable AI will drive our financial lives'Perret graduated from Duke University (BS, Chemistry, Biology) and previously served on the board of trusteesVerizon exec tells unemployed Gen Z they can always volunteer to stand out in the current bleak job market: ‘No one's going to say no to free work'chief talent officer Christina SchellingFigure AI CEO Brett Adcock says the robotics company is building 'a new species'Adcock received a Bachelor of Science in Business Administration from the University of FloridaLendingTree founder and CEO dies unexpectedly in weekend ATV accident at age 55Douglas Lebda: Chair/CEO, 20% shares, 78% influenceLead Independent DIrector Steven Ozonioa: Chairs Audit Committee and Chairs Compensation Committee; now the longest-tenured director (2011)SEC To Discourage ESG Shareholder Proposals MMGlass Lewis to End Share Voting Guidance Opposed by RepublicansGlass Lewis & Co. is ending its decades-long practice of providing recommendations for shareholder votes after receiving criticisms from Republican leaders for promoting pro-environmental, social and governance issues.Starting with the 2027 annual shareholder season, Glass Lewis will no longer give a “house view” on how investors should vote, according to a paper released by the firm.Instead, the firm's more than 1,300 clients who oversee a combined $40 trillion will be making their own decisions on corporate resolutions.Glass Lewis had previously given voting recommendations for more than 30,000 annual meetings on everything from executive pay to climate goals. The research firm said 55% of US investors voted based on its guidance. In Europe, about a quarter followed the house view.Meta removes Facebook page allegedly used to target ICE agents after pressure from DOJDuke University Has Officially Ended Its Full-Ride Scholarship For Black Students In Need Of Financial AssistanceBoard of Trustees (34: 14F20M)Duke President and Students (4):Vincent E. Price, President, Duke UniversityAndrew Greene*Sydney HuntRickard StureborgGod people from the same church (2):*Gregory V. Palmer – Retired Bishop, The United Methodist Church*Connie Mitchell Shelton – Bishop, United Methodist ChurchA journalist who also sits on the board of an insurance company (1):Ann Pelham – director of Canal Insurance Company since 2004Business Bros (27)Adam Silver – Commissioner, National Basketball AssociationMary T. Barra – Chair and CEO, General Motors CompanyEddy H. Cue – SVP of Services, AppleAmy Abernethy – Co-Founder, Highlander HealthMelissa Bernstein – Co-Founder, Melissa & Doug; Co-Founder, LifelinesMichael J. Bingle – Vice Chairman, Silver Lake Group*Lisa M. Borders – CEO, LMB Group, LLCTim Cook – CEO, AppleNancy-Ann DeParle – Managing Partner & Co-Founder, Consonance Capital PartnersAndrew H. Dillon – Attorney and Shareholder, Nathan Sommers Gibson DillonAnne Faircloth – President, Faircloth Farms*Grant H. Hill – Chairman, Hill VenturesKathryn A. Hollister – Retired Partner, Deloitte*Karen M. King – Managing Director & COO, Silver LakeGarheng Kong – Founder & Managing Partner, HealthQuest CapitalThomas H. Lister – Retired Senior Partner and Co-Managing Partner, PermiraSharon Marcil – Managing Director & Senior Partner & North America Regional Chair, Boston Consulting GroupPatricia R. Morton – formerly of JPMorgan and Deutsche BankDavid R. Peeler – Senior Advisor, Berkshire PartnersJ.B. Pritzker – Governor, State of Illinois (public official, but also billionaire businessman)Michael G. Rhodes – CEO, Ally FinancialNancy M. Schlichting – Retired CEO, Henry Ford Health System (corporate/health system executive)Michael R. Stone – Firm Partner, TPG (private equity executive)L. Frederick Sutherland – Retired EVP & CFO, ARAMARK CorporationDavid S. Taylor – Senior Advisor, Clayton Dubilier & Rice LLCJeffrey W. Ubben – Founder & Managing Partner, Inclusive Capital PartnersJames C. Zelter – President, Apollo Global ManagementGoodliest of the Week (MM/DR):DR: CEOs get something right?Mark Cuban Urges Companies To Share Stock Options With Employees Amid Rising CEO Pay GapHome Depot founder Arthur Blank donates $50 million to Atlanta's historically Black colleges and universities via foundationHoward Schultz said he's Worried — 'with a big W' — about AIHe drew parallels between the speed at which social media progressed, how regulation around social media lagged behind, and warned that AI is on the same trajectory.MM: Ron Conway skewers Mark Benioff in board resignation after 25 years: ‘I now barely recognize the person I have so long admired' DRMM: Houston American Energy Declassifies Board of Directors MMAssholiest of the Week (MM):Marc Benioff DRMarc Benioff Says Trump Should Send Guard Troops to San FranciscoDemocrat, Republican - is there an off switch for billionaires?He said it at the Dreamforce conference - the Salesforce conference where they talk about AI and stuffIn 2023, he threatened to take the conference to another city because of homelessness and drug use in the cityAt the time he made the threat, he was worth 8bnPOPULIST MATHThere are an estimated 8,000 or so homeless people in SFThe median home price in Oakland is 800kIf he bought EVERY homeless person a house, including the children, in cash, he would still be worth 4bn todayHe posted this last night - “safest Dreamforce ever” with a picture of him and a cop… so, national guard?: Maybe he meant he needs the National Guard at Salesforce's offices: Salesforce linked security breach fallout escalates with qantas leak - an estimated 1 BILLION records were hackedThe labor con jobVerizon exec tells unemployed Gen Z they can always volunteer to stand out in the current bleak job market: ‘No one's going to say no to free work'Yeah, just work for free, it'll be good for you!Gen Z's misery is real: Most workers in this economy lack a voice and are stuck in low-quality jobs, a massive Gates-backed study findsYeah, but just work for free!There's a shocking disparity between how high-income and low-income earners feel about the economyWhy? Working for free is like, really good for your resume and gap time!Sam Altman Says If Jobs Gets Wiped Out, Maybe They Weren't Even “Real Work” to Start WithRight! Your work was fake, so go work for free! Starving is much realer than your job was.Gavin NewsomGavin Newsom Vetoes Bill to Protect Kids From Predatory AISam AltmanSam Altman says OpenAI isn't 'moral police of the world' after erotica ChatGPT post blows upHeadliniest of the WeekDR: Divorced Tesla Fan Admits That His Cybertruck Is Repulsive to WomenDR: Lay's drastically rebrands after disturbing finding: 42% of consumers didn't know their chips were made out of potatoesMM: DirecTV screensavers will show AI-generated ads with your face in 2026I mostly find it funny that DirecTV still existsMM: Victoria's Secret Fashion Show Is Back to Featuring Hot Women After Failed Woke RebrandNow women of every size and color can be reminded how ugly they are because finally Victoria's Secret's won't put them on a runwayWho Won the Week?DR: Ugly or non-ugly women who divorce men who own CybertrucksMM: Men without cybertrucksPredictionsDR: Glass Lewis rebrands itself simply as GlassMM: Sam Altman is elected Moral Police Sergeant
Author and researcher Brené Brown joined host Reid Hoffman on stage recently in San Francisco for the 2025 Masters of Scale Summit. She reveals insights about how to lead courageously, the underrated skills leaders need to thrive, and why compassion is essential for success – even if it's currently being crowded out of the zeitgeist. Strong Ground: https://brenebrown.com/book/strong-ground/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today's show:*On a very special TWiST, Jason's joined by “one of the greatest investors in in the history of VC,” Steve Jurvetson of Future Ventures.Together, they look back at some of Steve's earliest investments and learnings, the promise and ultimate failure of nanotech, breaking down the AI hype cycle, the primacy of neural networks, the return of nuclear power, why “AI safety” might be illusory, and much more.It's a packed show full of deep insights from one of the greatest minds in technology today. Do not miss this ep!Timestamps:(00:00)Jason's 1-on-1 today with “one of the greatest investors in the history of VC,” Steve Jurvetson(00:03:04) The early origins of Steve's fascination with “deep tech”(00:08:03) Jason and Steve recall playing around with the TRS-80 (“The Trash-80”)(10:00) Perspective AI: Real insights, straight from your customers, and your first two months are on us. Just go to getperspective.ai/twist.(00:15:13) Keeping your portfolio diverse when so many companies look the same(20:00) .TECH: Say it without saying it. Head to get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.(00:20:49) The promise of nanotech and why it fell apart(00:25:46) Breaking down the “hype” cycle and how trends get co-opted(00:26:27) Why Moore's Law and the Power Law are so important for investors(30:00) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(00:33:36) Understanding the rise of GPUs and how they resemble tiny brains(00:51:32) Revisiting a classic clip of Steve talking about robots(00:54:04) How Jason and Steve got their hands on some of the earliest Tesla Roadsters(01:00:09) Flashback Clip: Elon predicts 2025 in 2015… how'd he do?(01:02:46) Why did the world turn SO strongly against nuclear energy?(01:16:06) Can we make AI “safe” in the age of GPT Psychosis? Is it too inscrutable?(01:21:54) Why Steve thinks technology will ultimately doom autocratic regimes.Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:TECH: Say it without saying it. Head to get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!Perspective AI: Real insights, straight from your customers, and your first two months are on us. Just go to getperspective.ai/twist.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
Amid dramatic disruption, what role should business play in building the future? Recorded live at the 2025 Masters of Scale Summit in San Francisco, Airbnb co-founder and CEO Brian Chesky shares his candid perspective on business, politics, creativity, and AI — taking listeners from Airbnb's humble beginnings to bold plans for the company's future. Through a designer's lens, Chesky also reveals the single question leaders must ask themselves, and explores how best to make tricky decisions in a volatile climate. Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this episode of Grow a Small Business, host Troy Trewin interviews Jennifer Ann Johnson, founder of True Fashionistas, Florida's leading lifestyle resale brand. Jennifer shares her inspiring journey from running a wedding planning business to building a thriving fashion resale empire. She talks about overcoming challenges like COVID-19 and hurricanes, the power of core values, and her belief in consistency and passion as keys to success. Jennifer also discusses leadership lessons, team culture, and how resilience and innovation helped her business grow from a small store to a 13,000-square-foot powerhouse. Why would you wait any longer to start living the lifestyle you signed up for? Balance your health, wealth, relationships and business growth. And focus your time and energy and make the most of this year. Let's get into it by clicking here. Troy delves into our guest's startup journey, their perception of success, industry reconsideration, and the pivotal stress point during business expansion. They discuss the joys of small business growth, vital entrepreneurial habits, and strategies for team building, encompassing wins, blunders, and invaluable advice. And a snapshot of the final five Grow A Small Business Questions: What do you think is the hardest thing in growing a small business? According to Jennifer Ann Johnson, the hardest thing in growing a small business is “staying the course.” She explains that it's easy to get distracted by competitors or trends, but true growth comes from staying focused, keeping your blinders on, and competing only with yourself. Her mindset is all about perseverance — focusing on your own path and goals rather than comparing yourself to others. What's your favorite business book that has helped you the most? Jennifer Ann Johnson's favorite business book that has helped her the most is “Begin With We” by Kyle McDowell. She loves it because it focuses on company culture and leadership, emphasizing how standing shoulder-to-shoulder with your employees—rather than above them—creates stronger teams and a more successful business. Are there any great podcasts or online learning resources you'd recommend to help grow a small business? Jennifer Ann Johnson recommends exploring The Confident Entrepreneur, her own podcast focused on leadership, growth, and confidence for business owners. She also provides valuable free tools and resources on her website to help entrepreneurs thrive. Beyond her work, she suggests tuning into other insightful shows like The Small Business Growth Podcast, The How of Business, and Masters of Scale by Reid Hoffman — all offering practical lessons on scaling, marketing, and managing small businesses effectively. What tool or resource would you recommend to grow a small business? Jennifer Ann Johnson recommends using The Confident Entrepreneur Podcast and her online resources as powerful tools for small business growth. Through her podcast, she shares real-world stories, leadership lessons, and actionable strategies on marketing, consistency, and scaling a business. Her website also offers free resources, coaching, and blogs that help entrepreneurs strengthen their mindset, improve operations, and build confidence while avoiding common business pitfalls. What advice would you give yourself on day one of starting out in business? Jennifer Ann Johnson's advice to herself on day one of starting out in business would be simple yet powerful — “You can do hard things.” She believes entrepreneurship is full of challenges, but success comes from trusting your abilities, facing obstacles head-on, and staying resilient no matter how tough things get. Book a 20-minute Growth Chat with Troy Trewin to see if you qualify for our upcoming course. Don't miss out on this opportunity to take your small business to new heights! Enjoyed the podcast? Please leave a review on iTunes or your preferred platform. Your feedback helps more small business owners discover our podcast and embark on their business growth journey. Quotable quotes from our special Grow A Small Business podcast guest: Success isn't about reaching a destination, it's about loving what you do and finding joy in the journey — Jennifer Ann Johnson The moment you stop learning is the moment you stop growing as a leader and as a business owner — Jennifer Ann Johnson Consistency, core values, and courage are the foundation of every thriving business — Jennifer Ann Johnson
Today's show:*Eric Glyman of Ramp joins us to share the fintech unicorn's growth secrets AND their Lab full of research data.On TWiST, Jason and Alex chat with Eric about Ramp's counter-intuitive mission — helping startups spend LESS money — PLUS they take a deep dive into the company's treasure trove of startup trend data. Why is there a huge spike in unemployed recent college trends? Is “static team size” as a big a story as Jason and Alex think? What does it actually take to get companies to adopt AI Agents? The answers all might be in these Ramp numbers.PLUS Eric joins us for some hot Founder Q's, and what's going on with all this Y Combinator drama? We're sifting through the angriest tweets for the inside scoop.FINALLY, Jason recommends some of his favorite startup accelerators of the moment (aside from his own) including…PearXArc from SequoiaAntlerSpeedrun from a16zTimestamps:(00:02:18) The 72-hour rule strikes again: Trump's China's tariff reversal(00:03:10) Why crypto got hit even HARDER than the stock market post-Trump announcement(00:07:32) Market manipulation “at a scale we've never seen before…”; what does this mean for everyday investors?(10:05) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(00:12:55) Ramp CEO Eric Glyman swings by to update us on his fintech unicorn's growth and their “Lab” for research data(20:09) Netsuite - Download the ebook CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twist(00:21:40) Is “static team size” a real trend? What the Ramp data shows…(00:26:25) Ramp's “counter-intuitive” mission: to help companies spend LESS money, not more.(30:24) Paper OS offers the largest library of AI-driven Workflows for both founders & fund managers. Claim your $10K credit at paperos.com/twist(00:38:07) WHY the huge spike in unemployed recent college grads? Especially among the guys?(00:49:16) What it actually takes to get companies to adopt AI agents into their processes(00:52:25) Why Jason thinks Eric is a top-tier TWiST guest. We're going through the metrics…(00:54:05) There's YC drama on social media now… we're spilling the tea.Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWISTNetsuite - Download the ebook CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twistPAPER OS - Building an empire? PaperOS offers the largest library of AI-driven Workflows for both founders & fund managers. Whether you're raising capital, launching a fund, or wading through diligence, PaperOS unlocks simplicity and scale for your ever-growing empire. Claim your $10K credit at paperos.com/twistGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
Reid Hoffman's relationship with Jeffrey Epstein is tenuous, controversial, and wrapped in layers of public explanation and regret. Hoffman has admitted that he invited Epstein to a 2015 dinner in Palo Alto (with luminaries like Elon Musk and Mark Zuckerberg) as part of fundraising efforts for the MIT Media Lab—on the basis that MIT leadership had “vetted” Epstein. He later issued a public apology, saying that while he believed the invitation was appropriate at the time, it was a serious error in judgment to associate with Epstein post-conviction.But deeper reporting has further complicated Hoffman's narrative. Documents indicate that Hoffman visited Epstein's private island, Little St. James, in 2014 (after Epstein's 2008 conviction), apparently connected with MIT-related fundraising. Other records show plans for Hoffman to stay in Epstein's New York townhouse and attend social engagements with him and other tech elites. Hoffman's defenders say his ties were limited to philanthropy and fundraising, but critics argue that even those interactions — especially occurring after Epstein's well-known legal disgrace — raise troubling questions about judgment, complicity, and the degree to which Epstein was able to rehab his social capital among elite tech circles.to contact me:bobbycapucci@protonmail.com
On a recent episode of Reid Hoffman's Possible podcast, he and Aria talk with comedian Stephen Colbert. They discuss how J.R.R. Tolkien helps The Late Show host make sense of AI, whether technology will ever be able to replicate the ‘micronutrients' of human interaction, and more. You can find this episode and more on the Possible podcast feed: https://play.megaphone.fm/awr0uaskrl6m7mfdaaeb0wSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
How do you create authentic partnerships to build scale? In this archival episode, Reid Hoffman talks with the iconic entrepreneur and Shark Tank star Daymond John about how he built FUBU from scratch. Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today's show:*Zach Dell of Base Power joins us at the top of today's show to talk about building batteries in Austin, that $1 billion investment, and why an “all of the above” energy strategy is the only way forward.PLUS Jason and Alex's thoughts on that Tesla non-upside down car announcement, growing resentments toward AI datacenters, Chinese robots actually going on sale, Tim Cook's potential Apple exit, xAI's Nvidia agreement and MUCH MORE.Timestamps:(00:02:10) A MAJOR GUEST! Zach Dell of Base Power joins us from the top of the show.(00:03:31) The basics of Base Power's business model: the best electron is the cheapest electron(00:08:38) Zach teases Base's new, time-saving approach to battery installation(00:10:32) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist(00:18:12) How Base's grid can help drive down overall energy prices(00:21:17) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(00:30:12) Sentry - New users get 3 months free of the Business plan (covers 150k errors). Go to http://sentry.io/twist and use code TWIST(00:36:20) Tesla did not announce an upside fan car… Oh well…(00:44:27) Buy your Chinese robot TODAY on Walmart dot com? Or not!(00:48:12) Is Tim Apple EXITING Apple? Who's next?(00:59:22) ANOTHER mega-deal? Now xAI is circling a Nvidia investment…Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twistSquarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWISTSentry - New users get 3 months free of the Business plan (covers 150k errors). Go to http://sentry.io/twist and use code TWISTGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
Reid Hoffman's relationship with Jeffrey Epstein is tenuous, controversial, and wrapped in layers of public explanation and regret. Hoffman has admitted that he invited Epstein to a 2015 dinner in Palo Alto (with luminaries like Elon Musk and Mark Zuckerberg) as part of fundraising efforts for the MIT Media Lab—on the basis that MIT leadership had “vetted” Epstein. He later issued a public apology, saying that while he believed the invitation was appropriate at the time, it was a serious error in judgment to associate with Epstein post-conviction.But deeper reporting has further complicated Hoffman's narrative. Documents indicate that Hoffman visited Epstein's private island, Little St. James, in 2014 (after Epstein's 2008 conviction), apparently connected with MIT-related fundraising. Other records show plans for Hoffman to stay in Epstein's New York townhouse and attend social engagements with him and other tech elites. Hoffman's defenders say his ties were limited to philanthropy and fundraising, but critics argue that even those interactions — especially occurring after Epstein's well-known legal disgrace — raise troubling questions about judgment, complicity, and the degree to which Epstein was able to rehab his social capital among elite tech circles.to contact me:bobbycapucci@protonmail.comBecome a supporter of this podcast: https://www.spreaker.com/podcast/the-epstein-chronicles--5003294/support.
How can AI really help advance medicine? Should patients and care teams be seeking second opinions from LLMs? This week, Reid and Aria sit down with physician-scientist Dr. David Fajgenbaum, who repurposes existing drugs to save lives—including his own. David shares his journey from receiving last rites as a young medical student to co-founding Every Cure, a nonprofit using AI to come up with ways existing drugs can be repurposed to treat every disease and every patient possible. On this special episode, filmed live in New York City, David, Reid, and Aria explore the circuit of hope, action, and impact that drives medical discovery; the technical and ethical challenges around accelerating AI in healthcare; “agent optimization” as the new “search engine optimization;” and what a future of faster diagnoses and treatment could look like. The result is a conversation about resilience, innovation, and unlocking cures that are already within our reach. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/ Topics: 3:00 - Hellos and intros 3:29 - A promise to his mother and the origin of AMF 6:23 - From grief support to medical school 9:18 - Near-death experiences and founding a research network 14:38 - What kept David going at death's door 16:19 - Discovering a potential treatment and testing it on himself 19:42 - Why drug repurposing is a faster, cheaper complement to drug discovery 22:14 - Co-founding Every Cure and scaling discovery with AI 25:20 - Demo: Building MATRIX and how the algorithm makes predictions 28:41 - Breast cancer and Lidocaine as a case study 30:07 - Why human review is essential in AI for medicine 34:08 - Car exhaust fumes example and FDA pathways 37:31 - Reid's surprise million-dollar donation for Every Cure compute 39:24 - What AI can unlock across healthcare 41:46 - Building an impact team to close the repurposing loop 47:32 - Improving systemic incentives for generics 54:58 - FDA approval pathways and label change challenges 57:21 - Three life-saving repurposing stories 1:02:20 - Rapid-fire questions Select mentions: Hidden Potential by Adam Grant Chasing My Cure by Dr. David Fajgenbaum Every Cure David's TED Talk: https://youtu.be/sb34MfJjurc?si=GcVleWHZuJ9MqLgS Manas AI Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Each episode seeks to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.
In this encore episode of Rapid Response, we chart OLIPOP's surging popularity. As Gen Z and millennials ditch sugary sodas, OLIPOP is leading the prebiotic beverage trend, sparking the likes of Coca-Cola and PepsiCo to enter the fray. OLIPOP's co-founder, CEO, and formulator, Ben Goodwin, shares how the brand is navigating the turbulence of rapid growth and rising competition, what leadership lessons he's had to embrace along the way, and whether healthy soda is actually healthy or just a TikTok-fueled fad.Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today's show:*How many weirdly circular mega-deals is OpenAI going to sign this year?On a new TWiST, Jason and Alex consider OpenAI's latest agreement with AMD, how the biggest American companies keep trading cash and chips back and forth, and whether or not the entire AI economy might be a house of cards.PLUS what kind of fan/leafblower tech is Tesla working on… what can Jevons Paradox tell us about the AI landscape… how easy is it to master games in the YC Arena… and WHY has NASA never built a base on the moon? We're asking the TOUGH QUESTIONS so you don't have to, only on the #1 tech podcast, “This Week in Startups.”Timestamps:(0:00) Jason and Alex open the show discussing hunting and traditional Texas meat exchanges(2:16) ANOTHER weirdly circular OpenAI mega-deal? How many mega-deals can one company MAKE?(3:50) Are all these “bizarre” OpenAI deals creating a house of cards?(10:00) Stripe Startups - Stripe Startups offers early-stage, venture-backed startups access to Stripe fee credits and more. Apply today on stripe.com/startups.(20:00) Oracle - Try OCI and save up to 50% on your cloud bill at https://oracle.com/twist(21:14) Is the Tesla Roadster 2 coming soon? Or maybe a leaf blower?!(22:00) Datacenters in space! Is it getting crowded up there?(26:22) Why no moon base yet? Jason demands a moon base.(27:00) We're playing games in the YC Arena… Can Jason guess which pitches got accepted?(30:00) Coda - Empower your startup with Coda's Team plan for free—get 6 months at https://www.Coda.io/twist(32:00) How Jason picks companies to invest in, based on a few signals and metrics(04500) We found out what Figure's bots are actually doing for BMW(53:00) Sharpies figured out how to make their pens here in the US… who's next?!(57:00) Could ChatGPT really replace Deloitte consultants? Considering the latest controversy…(01:03:29) It's another Gamma Pitch: Welcome Ryan Yannelli of NextVisit AI, which helps therapists take notesSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Stripe Startups - Stripe Startups offers early-stage, venture-backed startups access to Stripe fee credits and more. Apply today on stripe.com/startups.Oracle - Try OCI and save up to 50% on your cloud bill at https://oracle.com/twistCoda - Empower your startup with Coda's Team plan for free—get 6 months at https://www.Coda.io/twistGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
Today's show:Is Sora not just a copyright-killer but a TikTok-killer? Hear our review!The “This Week in Startups” team has been playing around inside OpenAI's viral app, which just hit #1 in the iOS Store. See all of Lon's creations, explore the land beyond the Uncanny Valley, and find out why the hottest new social app could stand to be a bit more social.PLUS Brave surpasses 100M MAUs… why Jason would sell ALL his OpenAI shares right away, Apple pulls the ICEBlock app from the App Store, AND how one founder hacked his local coffee shop to network and even get face time with a few VCs! It's all happening of a fast-paced Friday TWiST.Timestamps:(0:00) Why Jason started an Executive Training program at LAUNCH(05:17) Perplexity's Comet browser is now FREE to use; Jason unpacks their strategy(10:02) Monarch Money - Get 50% Off Monarch Money, the all-in-one financial tool at www.monarchmoney.com/TWIST(13:42) PLUS browser/search engine Brave passed 100M MAUs!(17:44) How a founder “hacked” his local coffee shop(20:06) Alphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at https://www.alpha-sense.com/twist(21:35) You need to make it EASY for people to give you feedback!(25:41) A look at the leanest startups around and how companies are doing more with less(30:11) LinkedIn Ads: Start converting your B2B audience into high quality leads today. We'll even give you a $100 credit on your next campaign. Go to http://LinkedIn.com/ThisWeekinStartups to claim your credit.(30:38) Why Jason would sell ALL his OpenAI shares right away!(38:56) Lon stops by to review the Sora app; the good, the bad, and the remixes!(48:45) Apple pulled the ICEBlock app… is this a free speech issue?(56:11) A new startup wants to fight gov't corruption… and keep a share of the proceedsSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Monarch Money - Get 50% Off Monarch Money, the all-in-one financial tool at www.monarchmoney.com/TWISTAlphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at https://www.alpha-sense.com/twistLinkedIn Ads: Thanks to our partner @LinkedInMktg. Start converting your B2B audience into high quality leads today. We'll even give you a $100 credit on your next campaign. Go to http://LinkedIn.com/ThisWeekinStartups to claim your credit.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
A daily quote to inspire the mind, gratitude to warm the soul, and guided breathing to energize the body. Quote: If you are not embarrassed by the first version of your product, you've launched too late.' - Reid Hoffman. Gratitude: All my five senses Guided Breathing: Equal Breathing. Visit TheDailyRefresh.com to share your unique piece of gratitude which will be featured on an upcoming episode, and make sure to watch the tutorial of how to make The Daily Refresh part of your Alexa Flash Briefings! Call to action: If you're ready to accomplish your #1 goal in 100 days, visit TheFreedomJournal.com and you'll be on your way. Use promo code 'refresh' as a thank you for listening to The Daily Refresh.
This week, the boys sling hot takes like baristas slinging lattes, diving into HR tech, AI, and corporate shenanigans with their signature wit. Kicking things off, they set the stage with a vibe check, chuckling over the wild ride of recruitment tech while side-eyeing the economic chaos of startups chasing venture capital like kids chasing ice cream trucks. No military leadership talk here, but they roast corporate missteps with the gusto of drill sergeants. The spotlight lands on JuiceBox, an AI-powered recruiting tool that snagged $36 million, including a $30 million Sequoia-led Series A. Chad's jazzed, calling it the “Capri Sun of HR tech” for its catchy name and $10 million revenue rocket. He wonders if they'll build a platform or get gobbled up in an acquisition faster than you can say “merger margarita.” Joel, the grumpy cat of the duo, sniffs history repeating, comparing JuiceBox to 2010s sourcing flops like Entelo. “Build fast, sell faster, or get squashed by LinkedIn,” he grumbles, predicting a big-tech beatdown. Next, they geek out over AI agents revolutionizing recruitment. Chad raves about Hackajob's agents that dig through applicant databases like treasure hunters, saving cash and recruiter sanity. Joel dreams of Chrome's new free Gemini AI turning browsers into job-search genies, scaring HR tech vendors like a horror flick. Chad warns, “Free? You're the product, kids!” as they lament job scams and hope AI security saves the day. LinkedIn's new Learning Career Hub gets a roasting—Chad calls it a “half-baked LinkedIn loaf” compared to slick competitors like Degreed. Joel likens it to Apple's VR headset: a panicked hedge against being left behind. They also torch Reid Hoffman's claim that work-life balance is a “red flag,” with Chad snapping, “Want me to work like a CEO? Pay me like one!” Joel laughs it off as Silicon Valley hot air, like a CEO dropping truth bombs after one too many kombuchas. Ford's CEO Jim Farley's $5 million pledge to train 15,000 workers by 2026 gets a collective eye-roll. Chad calls it “couch cushion change,” comparing it to Apple and Tesla's billion-dollar China training sprees. “Farley's begging for government handouts like a kid at a candy store,” he scoffs. Joel agrees, noting it's chump change next to a Super Bowl ad, and both warn U.S. companies are losing the EV race to China's manufacturing muscle. Finally, a Waymo self-driving car's illegal U-turn leaves cops stumped—no driver, no ticket! Chad, fresh off a Spanish speeding ticket by camera, wonders why the U.S. can't keep up with “Star Trek-level” tech. Joel predicts local governments will milk Google for fines to fund football fields. With automation on the rise, they're all in—just don't expect Robocop to sort it out anytime soon. Chapters 00:00 - Introduction 02:21 - Reflections on Current Events and Military Leadership 05:19 - Job Market Insights and Economic Concerns 09:13 - Cultural Commentary and Sports Events 16:11 - Tech Innovations in Recruitment 22:56 - Closing Thoughts and Future Outlook 25:06 - Evolving Market Strategies 27:13 - The Role of Agents in Recruitment 31:00 - Google's AI Integration and User Behavior 40:10 - LinkedIn's Challenges and Opportunities 46:32 - Ford's Workforce Development and EV Challenges 52:26 - Accountability in Autonomous Vehicles
Silicon Valley investor Reid Hoffman and cancer scientist Siddhartha Mukherjee join David Ignatius to discuss their new AI health start-up and the future of scientific discovery. Then, a global roundtable with voices from the Vatican, the United Nations and Kenya on how AI could impact the digital divide, people's everyday lives and human trust. Conversation recorded on Tuesday, September 23, 2025. Event sponsored by the University of Maryland.
Chomps co-founders Rashid Ali and Pete Maldonado had an unusual side hustle: selling meat sticks online. The co-founders join host Jeff Berman to reveal the phone call from Trader Joe's that changed everything, how they used lessons from failed startups, and how they built Chomps into a snack empire.Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Bulwark Capital https://KnowYourRiskPodcast.comHear directly from Zach Abraham as he shares insights in this FREE “Back To Basics” Webinar, TODAY at 3:30 Pacific. Register now at Know Your Risk Podcast dot com. Bizable https://GoBizable.comUntie your business exposure from your personal exposure with BiZABLE. Schedule your FREE consultation at GoBizAble.com today. Renue Healthcare https://Renue.Healthcare/ToddYour journey to a better life starts at Renue Healthcare. Visit https://Renue.Healthcare/Todd Alan's Soaps https://www.AlansArtisanSoaps.comUse coupon code TODD to save an additional 10% off the bundle price.Bonefrog https://BonefrogCoffee.com/toddThe new GOLDEN AGE is here! Use code TODD at checkout to receive 10% off your first purchase and 15% on subscriptions.LISTEN and SUBSCRIBE at:The Todd Herman Show - Podcast - Apple PodcastsThe Todd Herman Show | Podcast on SpotifyWATCH and SUBSCRIBE at: Todd Herman - The Todd Herman Show - YouTubeEpisode Links:Terry Moran on Trump: “It's an administration of trolls, led by trolls… because we're a nation of trolls now”WATCH: Jon Ossoff admits that he knowingly lied to the nation about Joe Biden's cognitive decline because beating President Trump was more important to him. Georgia, your Senator lied to you— because he cares more about Democrats having power than our state's best interests.Jay Inslee - “who is antifa?” Soros and Reid Hoffman are targets of investigation for funding radical left wing organizations‘50501' is a name you might not know right now, but must learn ASAP…WHITEHOUSE EO: “Countering Domestic Terrorism and Organized Political Violence.”These are not revolutionaries. These are all regular leftists you see every day, outright advocating for murder.BREAKING: UK government makes Digital IDs mandatory: 'You will not be able to work in the United Kingdom if you do not have a digital ID, it's as simple as that.'Years have passed, but the vision remains unchanged—and more chilling than ever. A clip of WEF founder Klaus Schwab recounts a discussion with the mayor of Los Angeles. In it, he fantasizes about a 2030 where the city is "private car-driven free," with highways converted into parks. This was never a fleeting comment. It was an early blueprint.
Today's show:Sora 2 will generate a video of whatever you like and respects no IP (unless they opt out)On a brand new TWiST, Jason and Alex check out Sora 2, the latest text-to-video app from TWiST 500 mainstays OpenAI, and look at some of the video videos that have already emerged from the TikTok-style scrolling video app. (TikSlop?)THEN we're considering the case of “AI actress” Tilly Norwood, and whether her big debut is a legit shift in the world of entertainment or just a marketing gimmick-slash-sales pitch.PLUS Jason's thoughts on the Wealthfront IPO, how Spotify shifted the entire music economy, Jason's pitch for making bets with stock purchases, why Americans need more financial literacy, AND another check-in with the sharps over at Polymarket.Timestamps:(0:00) What does the government shutdown mean for startups? Not much?(04:21) Jason's an investor in Wealthfront… hear his thoughts on their potential IPO(08:14) Why Jason thinks the death of Boomers will boost crypto(10:21) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(17:26) Why is everyone so excited for Sora… but not Meta's app?(19:49) CLA - Get started with CLA's CPAs, consultants, and wealth advisors now at https://claconnect.com/tech(28:38) Is Tilly Norwood just a gimmick or Hollywood's next hot ingenue?(29:15) Perspective.ai - Real insights, straight from your customers, and your first two months are on us. Just go to getperspective.ai/twist.(35:58) POLYMARKET: When is OpenAI's browser coming out?!(40:17) How Spotify changed the entire economy of music… and when a Founder/CEO should hang it up.(47:24) Why Jason thinks Americans need better financial education and literacy(49:39) Audience Q: What's the best place to buy secondaries?(52:49) Why you should bet small while you're learningSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!CLA - Get started with CLA's CPAs, consultants, and wealth advisors now at https://claconnect.com/techPerspective.ai - Real insights, straight from your customers, and your first two months are on us. Just go to getperspective.ai/twist.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
How do you find joy in your life? For entrepreneur, venture capitalist, and author Reid Hoffman, it's through the act of genuine, honest, and intimate conversations with friends. Once a self-described misfit, in college, Reid finds his place. He connects with people who share not necessarily his interests but his curiosity, and his dedication to asking big questions. It is in asking the big questions, in discussing the answers, that Reid learns and grows – and begins to discover the meaning of his life.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Figma burst into the public eye in 2022 after Adobe was blocked from buying the design startup for $20 billion. This chapter set the stage for an even bigger milestone at Figma: a splashy IPO this summer at nearly double that valuation. Dylan Field, Figma's co-founder and CEO, joins Rapid Response to share what distinguishes Figma from competitors, and why design is increasingly at the center of every industry in today's software-driven economy. Field also reflects on the pressures and opportunities of leading as a next-generation, tech-native CEO, and offers practical advice on upskilling in an AI-powered world.Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today's show:How do you get investors excited about jets when they're hyper-focused on new AI tools?In a fresh TWiST 500 interview, Alex sits down with Blake Scholl of Boom Supersonic to talk about the Overture, the world's fastest plane that recently broke the sound barrier over the Mojave Desert. (That's a first for a private company, rather than a military or government.)Hear about the secrets to avoiding a noisy and disruptive sonic boom, using satellites to set the most efficient routes, designing the Overture's complex engine, dispelling the common myth that hardware startups are money pits and much much more.PLUS we've got two brand new companies entering our Gamma Pitch Deck Competition. Time to see how they stack up to our first impressive entrant, Where2Wheel.Timestamps:(02:22) Introducing Blake Scholl from Boom Supersonic(04:03) How Boom is improving on the classic Concorde experience(08:29) How hyper-fast Overture flights could change passenger behavior(10:02) Gusto. Check out the online payroll and benefits experts with software built specifically for small business and startups. Try Gusto today and get three months FREE at Gusto.com/twist.(11:10) The long road to breaking the speed barrier(14:34) How satellites could help guide Boom's planes(16:37) The next milestones to check off Blake's list(19:13) Breaking up the jet engine duopoly(20:57) Nexos.ai Stop Shadow AI in its tracks with the unified platform for secure AI adoption and productivity. Try it with a free 14-day trial at nexos.ai/twist.(24:28) How 3D printing speeds up the R&D process(30:26) DevStats translates complex engineering metrics into a shared language everyone at your company can understand. Get 20% off by going to https://www.DevStats.com/twist(34:10) Gamma Pitch Deck Competition: Confy vs. The Drive AISubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Gusto. Check out the online payroll and benefits experts with software built specifically for small business and startups. Try Gusto today and get three months FREE at Gusto.com/twist.Nexos.ai Stop Shadow AI in its tracks with the unified platform for secure AI adoption and productivity. Try it with a free 14-day trial at nexos.ai/twist.DevStats translates complex engineering metrics into a shared language everyone at your company can understand. Get 20% off by going to https://www.DevStats.com/twistGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
Travis and producer Eric break down one of the most polarizing topics in entrepreneurship: is it better to bootstrap a business, or raise outside capital? Drawing on personal experience and lessons from startup culture, Travis reveals the biggest mistakes founders make when chasing VC funding, why Silicon Valley's obsession with investment misleads so many, and the first principles everyone should use to decide how to launch any new company. On this episode we talk about: The dangers and downsides of raising funding too early—even if the “checklist” seems to fit your business Why bootstrapping builds discipline, pressure, and actual proof of concept (and how to get creative when money is tight) When venture capital makes sense—and all the hidden costs of taking outside money, from loss of control to preferential contracts How AI is changing the software startup equation, and shrinking the need to raise massive amounts of funding Lessons learned from infamous failures (like Quibi) and the right ways to audit your business before chasing investment Top 3 Takeaways 1. Bootstrapping is almost always the better first move; it boosts discipline, real market feedback, and keeps control in the founder's hands.2. Raising outside capital adds pressure, complex contracts, and doesn't guarantee success; cash alone never fixes a business that lacks product-market fit.3. Use trusted frameworks (like Reid Hoffman's Blitzscaling checklist), consult experienced founders, and remember: don't give away control unless it's truly required for growth. Notable Quotes “If at all possible, bootstrap first—even just to prove your concept. Outside money makes everything more complicated.” “Cash doesn't solve all your problems. There are usually bigger issues at play—product, marketing, market fit—that have nothing to do with funding volume.” “The moment you take other people's money, it gets harder, not easier; discipline and focus will always win.” Connect with Travis Chappell: LinkedIn: Travis Chappell on LinkedIn Twitter/X: @travischappell Instagram: @travischappell Website: travischappell.com ✖️✖️✖️✖️
Today's show:Friend's new AI pendant just wants to be your new pal. So why do New Yorkers hate them?On a brand-new TWiST, Jason and Alex consider the Friend AI pendant, which listens to everything you say all day and then sends you snarky texts about it.WIRED says it's unhelpful and will make your friends hate you. New Yorkers are so sick of their aggressive subway ads, they're tagging them with graffiti. But what do Jason and Alex think of the wearable companion?PLUS the value of bringing your last team with you to your new project… why partnerships often lead to purchases… Producer Claude got an upgrade… two fresh TWiST 500 companies… the rise and fall and further fall of Tai Lopez… AND Jason explains the rules of private jets.Timestamps:(0:00) Jason congratulations the Eagles while wondering what's going on with Philly fans(03:23) New Yorkers are not in love with these Friend AI pendants and their subway ads(10:08) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(11:28) Show Continues…(13:49) Are people actually using AI agents? Is it still too early?(17:01) Startup Lesson: The value of bringing your last team with you(19:27) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(20:43) Anthropic released the new Claude… can they catch back up with Grok?(27:13) Why Circle's community app is blowing up all of the sudden(29:23) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit https://www.aws.amazon.com/startups/credits(30:48) How startups SHOULD measure growth and profitability. And why you need to show your work.(36:42) Why human writers are about to be MORE valuable in the age of AI Slop.(42:20) TWO new startups are joining the TWiST 500… Jason's thoughts on Phia and Huxe(46:23) Influencer and bookshelf haver Tai Lopez is under investigation by the SEC! A look back at a viral superstar…(54:11) Jason explains the rules of flying in private jetsSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWISTLemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twistAWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit https://www.aws.amazon.com/startups/creditsGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
Reid Hoffman is the co-founder of LinkendIn, Manas AI, and Inflection AI. As an investor at Greylock, he is one of the leading figures in the tech industry, working at the forefront of AI development. In this episode, Reid and Robinson talk all about the future of AI. They begin by covering the worst case scenario—doomsday—and why Reid is optimistic about our chances. From there, they turn to how AI could help us cure cancer, replace therapists, enable us to be more powerful agents, and make our lives better. Reid's most recent book is Superagency: What Could Possibly Go Right with Our AI Future (2025).Reid's Website: https://www.reidhoffman.orgSuperagency: https://a.co/d/hdSZeCYOUTLINE00:00:00 Introduction00:01:09 Why Won't AI Destroy Humanity?00:06:39 Will AI Be Good or Bad for Employment?00:08:20 On Optimism00:10:10 It Isn't Inevitable that AI Will Wipe Out Human Life00:19:03 How to Align AI with Human Interests00:24:40 Reid's Interest in Friendship00:32:13 Why AI Can't be Our Friends00:36:33 Could AI Replace Therapists?00:45:18 Using AI to Cure Cancer00:52:04 Will AI Extinguish Humanity with a Virus?01:00:02 How Will AI Make Us More Powerful Agents?01:07:06 Will Academia Be Revolutionized by AI?01:15:10 Are You an AI Native?01:17:36 How to Invest in AIRobinson's Website: http://robinsonerhardt.comRobinson Erhardt researches symbolic logic and the foundations of mathematics at Stanford University, where he is also a JD candidate in the Law School.
In this episode of Pioneers of AI, Jeffrey Katzenberg and ChenLi Wang of the venture capital firm WndrCo share why storytelling is essential for building transformative companies and how AI shapes their work. Learn more about Pioneers of AI: http://pioneersof.ai/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today's show:Factory, a Sequoia-backed producer of AI agents for programming, raised $50 million at a $300 million valuation. So Jason and Alex are wondering… how much capital is TOO MUCH?We're going deep on a question that often perplexes founders: How would weigh a HUGE potential market against STIFF pre-existing competition.PLUS that Neon app that records your calls deleted itself, why AI ISN'T taking away all the radiology jobs yet, how inherent biases impact everyone's view of the economy, ChatGPT may be getting ads very soon, and MUCH MUCH MORE.Timestamps:(0:00) The Neon app: why would anyone let an app record all of their phone calls?(04:43) Another -slop term… What is THINKSLOP?!(09:46) .TECH: Say it without saying it. Head to get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.(11:25) Why is TikTok US only worth $14 billion?!(17:10) Wait, why ISN'T AI taking jobs away from radiologists?(20:06) Public - Take your investing to the next level with Public. Build a multi-asset portfolio and earn 4.1% APY on your cash—with no fees or minimums. Start now at public.com/twist(28:38) How can xAI afford to sell AI to the US gov't for 42 cents?(29:37) Alphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at https://www.alpha-sense.com/twist(33:44) How inherent biases impact everyone's view of the economy.(46:29) Why is everyone dunking on Meta's new SlopTok app?(53:37) It certainly seems like ChatGPT is going to get ads soon…(03:49) The first entry in our Gamma Pitch Deck Competition is II off-roading marketplace Where2WheelSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:.TECH: Say it without saying it. Head to get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.Public - Take your investing to the next level with Public. Build a multi-asset portfolio and earn 4.1% APY on your cash—with no fees or minimums. Start now at public.com/twistAlphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at https://www.alpha-sense.com/twistGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
Mark talks about Trump's appearance at the UN; the Obama Presidential library in Chicago; Reid Hoffman's funding of protests; Staten Island priciest home sold; Johnny Carson former house is for sale for $110 million; the NYC Mayoral race; Netanyahu's powerful speech at the UN; Trump vs. Curtis Sliwa and Jack Schlossberg running for Jerry Nadler's seat in Congress.
Mark talks about Trump's appearance at the UN; the Obama Presidential library in Chicago; Reid Hoffman's funding of protests; Staten Island priciest home sold; Johnny Carson former house is for sale for $110 million; the NYC Mayoral race; Netanyahu's powerful speech at the UN; Trump vs. Curtis Sliwa and Jack Schlossberg running for Jerry Nadler's seat in Congress. See omnystudio.com/listener for privacy information.
What happens when your team doesn't trust each other? How can you repair damaged trust at work? How has technology changed the way we decide who to trust? Author and trust researcher Rachel Botsman joins host Jeff Berman to tackle these questions and more. Her latest book is How to Trust and Be Trusted: https://www.rachelbotsman.com/work/how-to-trust-and-be-trustedSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today's show:What is “workslop”? And is it already slowing you down at the office?On a new This Week in Startups, we've got full co-host quorum with JCal, Alex, AND Lon tackling a meaty docket of news at the cross-section of tech, startups, and pop culture.For starters: A new Harvard/Stanford study suggests that AI isn't massively improving workplace efficiency because SOME workers aren't using it properly. Are low-quality, lazily-assembled AI outputs costing US enterprises millions in lost productivity? It's certainly possible based on these results.PLUS, why YouTube invited back all those banned creators… a deep-dive into CA's new social media law that's dividing tech and civil rights advocacy groups… what we can learn from Stripe's mega-share buyback… a look at what Polymarket's sharps think will happen with the US TikTok deal… and much more.Timestamps:(0:00) Intro. What will South Park have to say about prediction markets?(06:06) Alibaba's new AI model will turn you into any celebrity… can you still believe what you see?(09:49) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist(11:03) Show Continues…(19:42) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit https://www.aws.amazon.com/startups/credits(21:02) Is CA's new proposed law a boon for civil rights, or a weapon against free speech?(29:47) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(32:21) Why YouTube invited banned creators back(41:24) What is Workslop? And is it costing companies MILLIONS?(48:42) PolyMarket asks… when will the US TikTok deal go down?(52:27) Would Jason invest in Tether?(01:01:29) Why Stripe is buying back so many shares… and what the future may hold.(01:12:16) Another Reddit Rapid Response: should startups do pilot programs?Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twistAWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit https://www.aws.amazon.com/startups/creditsNorthwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
For an organization built around responding to crises around the globe, Mercy Corps now finds itself at the center of its own trauma. Following the Trump administration's aid cuts, two-thirds of Mercy Corps' US-funded programs have been rescinded. CEO Tjada D'Oyen McKenna joins Rapid Response to share how she's leading her team amid immense pressure—scrambling to find new ways to help those in need, even as she resorts to layoffs to keep the business afloat. McKenna reveals what she's hearing from her team of aid workers on the ground in Gaza, and why she isn't running away from burnout but embracing it. Like many business leaders experiencing political or economic volatility right now, McKenna is faced with a complex conundrum: fight, flight, or freeze.Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today's show:New proposal on H-1B visas… and it's pretty similar to Jason's pitch from last month!On a new TWiST, Jason and Lon wonder if the White House is watching the pod and borrowing some of our best ideas! Specifically, the new $100K H-1B visa proposal sounds a lot like Jason's suggestion from August… with a few significant tweaks.PLUS we're looking at the latest news about the US TikTok entity, why Jason's not concerned about the new algorithm, the explosion of major data centers in Scandinavia, the European Commission's scaling back of anti-cookie regulations, AND the first big marketing push from virtual assistant startup Howie! That's a packed show!Timestamps:(0:00) Alex is out today so Jason and Lon introduce the show.(04:11) Did they borrow their new H-1B visa proposal from JCal?(10:10) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(11:28) Show Continues…(19:21) Public - Take your investing to the next level with Public. Build a multi-asset portfolio and earn 4.1% APY on your cash—with no fees or minimums. Start now at public.com/twist(20:28) Show Continues…(26:42) Answering YOUR pressing H-1B questions.(30:13) Stripe Startups - Stripe Startups offers early-stage, venture-backed startups access to Stripe fee credits and more. Apply today on stripe.com/startups.(31:30) Show Continues…(32:51) The Murdochs are likely joining the TikTok deal…(34:38) Why Jason's not concerned about TikTok being in the hands of mostly Trump allies(39:29) A look inside the Nordic data center boom and why it's happening(01:03:32) Checking out Howie's first ad… how much did it cost to make?Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWISTPublic - Take your investing to the next level with Public. Build a multi-asset portfolio and earn 4.1% APY on your cash—with no fees or minimums. Start now at public.com/twistStripe Startups - Stripe Startups offers early-stage, venture-backed startups access to Stripe fee credits and more. Apply today on stripe.com/startups.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
This week we talk about corruption, influencers, and pro-monarchy protests.We also discuss Nepalese modern history, Gen Z, and kings.Recommended Book: Superagency by Reid Hoffman and Greg BeatoTranscriptThe Federal Democratic Republic of Nepal, usually referred to as just Nepal, is a country located in the Himalayas that's bordered to the northeast by China, and is otherwise surrounded by India, including in the east, where there's a narrow sliver of India separating Nepal from Bhutan and Bangladesh.So Nepal is mostly mountainous, it's landlocked, and it's right in between two burgeoning regional powers who are also increasingly, in many ways, global powers. Its capital is Kathmandu, and there are a little over 31 million people in the country, as of 2024—more than 80% of them Hindu, and the country's landmass spans about 57,000 square miles or 147.5 square kilometers, which is little smaller than the US state of Illinois, and almost exactly the same size as Bangladesh.Modern Nepal came about beginning in the mid-20th century, when the then-ruling Rana autocracy was overthrown in the wake of neighboring India's independence movement, and a parliamentary democracy replaced it. But there was still a king, and he didn't like sharing power with the rest of the government, so he did away with the democracy component of the government in 1960, making himself the absolute monarch and banning all political activities, which also necessitated jailing politicians.The country was modernized during this period, in the sense of building out infrastructure and such, but it was pulled backwards in many ways, as there wasn't much in the way of individual liberties for civilians, and everything was heavily censored by the king and his people. In 1990, a multiparty movement called the People's Movement forced the king, this one ascended to the throne in 1972, to adopt a constitution and allow a multiparty democracy in Nepal.One of the parties that decided to enter the local political fray, the Maoist Party, started violently trying to shift the country in another direction, replacing its parliamentary system with a people's republic, similar to what was happening in China and the Soviet Union. This sparked a civil war that led to a whole lot of deaths, including those of the King and Crown Prince. The now-dead king's brother stepped in, gave himself a bunch of new powers, and then tried to stomp the Maoist Party into submission.But there was a peaceful democratic revolution in the country in 2006, at which point the Maoists put down their arms and became a normal, nonviolent political party. Nepal then became a secular state, after being a Hindu kingdom for most of their modern history, and a few years later became a federal republic. It took a little while, and there was quite a bit of tumult in the meantime, but eventually, in 2015, the Nepalese government got a new constitution that divided the country into seven provinces and made Nepal a federal democratic republic.What I'd like to talk about today is what has happened in the past decade in Nepal, and how those happenings led to a recent, seemingly pretty successful, series of protests.—In early 2025, from March through early June, a series of protests were held across Nepal by pro-monarchy citizens and the local pro-monarchy party, initially in response to the former King's visit, but later to basically just show discontentment with the current government.These protests were at least partly politically motivated, in the sense of being planned and fanned into larger conflagrations by that pro-monarchy party—not truly grassroots sort of thing—but they grew and grew, partly on the strength of opposition to the police response to earlier protests.That same distaste carried through the year, into September of 2025, when the Nepalese government announced a ban on 26 social media platforms, including Facebook, Instagram, Reddit, and Youtube, because the companies behind these platforms ostensibly failed to register under the Ministry of Communication and Information Technology's new rules that required, among other things, they have local liaisons that the government could meet with in person, and complain to if a given network failed to remove something they didn't like quickly enough.The general sense about that ban is that while this failure to properly register was used as justification for shutting down these networks, which are incredibly popular in the country, the real reason the government wanted to shut them down at that moment was that a trend had emerged online in which the rich and powerful in the country, and especially their children, many of whom have become online influencers, were being criticized for their immense opulence and for bragging about their families' vast wealth, while everyone else was comparably suffering.This became known as the Nepobaby or Nepo Kid trend, hashtag Nepobaby, which was a tag borrowed from Indonesia, and the general idea is that taxpayer money is being used to enriched a few powerful families at the expense of everyone else, and the kids of those powerful families were bragging about it in public spaces, not even bothering to hide their families' misdeeds and corruption.This, perhaps understandably, led to a lot more discontent, and all that simmering anger led to online outcries, the government tried to stifle these outcries by shutting down these networks in the country, but that shut down, as is often the case in such situations, led to in-person protests, which started out as peaceful demonstrations in Kathmandu and surrounding areas, but which eventually became violent when the police started firing tear gas and rubber bullets at the crowds, causing 19 deaths and hundreds of injuries.The ban was implemented on September 4 and then lifted, after the initial protests, on September 8, but the government's response seems to have made this a much bigger thing than it initially was, and maybe bigger than it would have become, sans that response.It's worth mentioning here, too, that a lot of young people in Nepal rely on social media and messaging apps like Signal, which was also banned, for their livelihood. Both for social media related work, and for various sorts of remittances. And that, combined with an existing 20% youth unemployment rate, meant that young people were very riled up and unhappy with the state of things, already, and this ban just poured fuel on that flame.On that same note, the median age in Nepal is 25, it's a relatively young country. So there are a lot of Gen Zers in Nepal, they're the generation that uses social media the most, and because they rely so heavily on these networks to stay in touch with each other and the world, the ban triggered a mass outpouring of anger, and that led to huge protests in a very short time.These protests grew in scope, eventually leading to the burning of government buildings, the military was called in to help bring order, and ultimately the Home Minister, and then the Prime Minister, on September 8 and 9, respectively, resigned. A lot of the burning of government buildings happened after those resignations; protestors eventually burned the homes of government ministers, and the residences of the prime minister and president, as well.The protestors didn't have any formal leadership, though there were attempts during the protests by local pro-monarchy parties and representatives to position the protests as pro-King—something most protestors have said is not the case, but you can see why that might have worked for them, considering those pro-monarchy protests earlier this year.That said, by September 10, the military was patrolling most major cities, and on the 11th, the president, head general, and Gen Z representatives for the protestors met to select an interim leader. They ended up using Discord, a chat app often used by gamers, to select a former Supreme Court Justice, Sushila Karki, as the interim prime minister, and the first woman to be prime minister in Nepalese history. Parliament was then dissolved, and March 5 was set as the date for the next election. Karki has said she will remain in office for no more than six months.As of September 13, all curfews had been lifted across Nepal, the prime minister was visiting injured protestors in hospitals, and relative calm had returned—though at least 72 people are said to have been killed during the protests, and more than 2,000 were injured.There are currently calls for unity across the political spectrum in Nepal, with everyone seeming to see the writing on the wall, that the youths have shown their strength, and there's a fresh need to toe the new line that's been established, lest the existing parties and power structures be completely toppled.There's a chance that this newfound unity against government overreach and censorship will hold, though it's important to note that the folks who were allegedly siphoning resources for their families were all able to escape the country, most without harm, due to assistance from police and the military, and that means they could influence things, from exile or after returning to Nepal, in the lead-up to that March election.It's also possible that the major parties will do more to favor the huge Gen Z population in Nepal from this point forward, which could result in less unemployment and freer speech—though if the King and the pro-monarchy party is able to continue insinuating themselves into these sorts of conversations, positioning themselves as an alternative to the nepotism and corruption many people in the area have reasonably come to associated with this type of democracy, there could be a resurgent effort to bring the monarchy back by those who have already seen some success in this regard, quite recently.Show Noteshttps://restofworld.org/2025/nepal-gen-z-protest/https://apnews.com/article/nepal-ban-social-media-platform-3b42bbbd07bc9b97acb4df09d42029d5https://apnews.com/article/nepal-new-prime-minister-protests-karki-0f552615029eb12574c9587d8d76ec46https://www.bbc.com/news/articles/crkj0lzlr3rohttps://kathmandupost.com/visual-stories/2025/09/08/gen-z-protest-in-kathmandu-against-corruption-and-social-media-banhttps://en.wikipedia.org/wiki/2025_Nepalese_Gen_Z_protestshttps://en.wikipedia.org/wiki/2025_Nepalese_pro-monarchy_protestshttps://en.wikipedia.org/wiki/Nepal This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit letsknowthings.substack.com/subscribe
Today's show:On an action-packed TWiST, Alex and Jason check out Meta's latest wearables, which promise to fix the “constantly staring down at your phone” problem and prevent you from blocking that little light letting others know you're filming them. Think the upgrade is worth $799 of your hard-earned money?PLUS, Lovable CEO Anton Osika stops by to answer YOUR questions, talk about how people are using the iconic vibecoding app, balancing accessibility and user engagement with the need to actually bring in revenue, and why Stockholm has become arguably Europe's leading tech hub.AND Beehiiv joins with Discord, Google bakes Gemini into Chrome, and MORE of the week's biggest tech news. Check out all this and more in a brand-new “This Week in Startups”!Timestamps:(0:00) Why Jason thinks Meta's new $799 Smart Ray Bans, which covertly record people in 3K, are creepy!(04:14) Why, in the technology business, not quitting is how you succeed.(09:47) .TECH: Say it without saying it. Head to get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.(10:54) Show Continues…(17:02) Anton Osika from Lovable calls in from Stockholm: Why he thinks it's Europe's biggest tech hub.(20:37) Sentry - New users get 3 months free of the Business plan (covers 150k errors). Go to http://sentry.io/twist and use code TWIST(21:44) A look at Lovable's new security features, to make founders feel more confident in their vibe coding(27:31) How Lovable is balancing engagement with the need to make money(29:55) Alphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at https://www.alpha-sense.com/twist(31:03) Show Continues…(42:29) Anton's tactical advice for founders who want to build a community around their product.(49:14) A viewer asks: Is vibe coding CHEATING?(59:01) Google is baking Gemini into Chrome… but how will it work? And what about privacy?(01:05:05) Beehiiv links up with Discord. Why Alex has a few concerns!(01:11:01) Responding to some of YOUR comments. (Leave us reviews and comments on Apple and Spotify!)Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:.TECH: Say it without saying it. Head to get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.Sentry - New users get 3 months free of the Business plan (covers 150k errors). Go to http://sentry.io/twist and use code TWISTAlphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at https://www.alpha-sense.com/twistGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
A great mentor can supercharge your career. That's why author and entrepreneur Janice Omadeke wanted to make it easier for people to connect with the best possible mentors. She joins host Jeff Berman to reveal the insights from her book, Mentorship Unlocked, and lessons from her own journey as the founder of a tech platform for corporate mentorship.Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Pablos Holman is a hacker and inventor and the author of Deep Future: Creating Technology that Matters, the indispensable guide to deep tech. Previously, Pablos worked on spaceships at Blue Origin and helped build The Intellectual Ventures Lab to invent a wide variety of breakthroughs. Pablos also hosts the Deep Future Podcast and is managing partner at Deep Future.This episode is brought to you by:Cresset prestigious family office for CEOs, founders, and entrepreneurs: https://cressetcapital.com/timMaui Nui Venison, delicious, nutrient-dense, and responsible red meat: https://mauinuivenison.com/lp/timAG1 all-in-one nutritional supplement: https://drinkag1.com/timTimestamps:00:00 Intro02:12 The hacker mindset33:05 Nuclear52:35 Autonomous ships58:48 Pragmatic optimism01:00:29 Risk tolerance01:04:50 Blue Origin01:11:59 Zero Effect philosophy01:34:43 China01:43:07 Taiwan01:45:04 AI01:50:42 Salsa02:08:44 Deep tech investing*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissPast guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, Margaret Atwood, Mark Zuckerberg, Peter Thiel, Dr. Gabor Maté, Anne Lamott, Sarah Silverman, Dr. Andrew Huberman, and many more.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
As the fashion world navigates an unprecedented wave of turnover from Chanel to Dior, WSJ. Magazine's Editor in Chief, Sarah Ball joins Rapid Response to explore the most closely watched New York Fashion Week in years — what she calls "a September to remember." Ball also shares insights about how Vogue is poised to take shape post-Anna Wintour, the shockwaves from Georgio Armani's recent passing, AI's impact on fashion creatives, and how the role of influencers and social media is noticeably reshaping where the industry is headed.Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
On the latest episode of Reid Hoffman's Possible podcast, he and Aria talk with comedian Stephen Colbert. They discuss how J.R.R. Tolkien helps The Late Show host make sense of AI, whether technology will ever be able to replicate the ‘micronutrients' of human interaction, and more. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
This episode is a solo Q&A session where I answer a bunch of questions. We covered a ton of ground, from personal health protocols to professional frameworks and creative projects. This episode is brought to you by:Eight Sleep Pod Cover 5 sleeping solution for dynamic cooling and heating: EightSleep.com/Tim (use code TIM to get $350 off your very own Pod 5 Ultra.)Monarch Money track, budget, plan, and do more with your money: MonarchMoney.com/Tim (50% off your first year at monarchmoney.com with code TIM)Shopify global commerce platform, providing tools to start, grow, market, and manage a retail business: https://shopify.com/tim (one-dollar-per-month trial period)Timestamps: [00:00:00] Start[00:06:00] Coyote retail distribution challenges and data gathering.[00:09:12] Elbow surgery recovery: sequencing, decongestion, Marc Pro device, peptides, BFR training.[00:16:14] California vs. Austin for builders, mechanical engineers, and tech startups.[00:19:06] Using AI for medical advice workflow (and cross-referencing with professionals).[00:23:51] Current supplement regimen and PAGG/AGG status.[00:31:54] California vs. Texas considerations for aspiring parents.[00:32:48] Saying "No" to good things for "Hell, yes" moments.[00:34:34] Philanthropy lessons learned since starting Saisei Foundation.[00:37:45] Something I've changed my mind about recently: intermittent fasting.[00:42:44] Precious items from childhood I still keep: D&D relics and marine biology books.[00:43:03] Bucket list hike: Glacier National Park.[00:43:42] How the catalytic chaos of publishing The 4-Hour Chef led to launching this podcast.[00:45:52] Bringing delight vs. sixth-gear, high-performance focus.[00:49:05] Thoughts on extended human fasting research from the Soviet era.[00:52:58] Most magical New Mexico experience: Mountain Cloud Zen Center meditation retreat.[00:53:22] Meta skills for the AI era: Hyper-adaptability and world-class learning.[00:54:01] The (real and ideal) future of CØCKPUNCH/Legends of Varlata.[00:59:47] Competitive chess training enhancement: glucose management, intermittent fasting, MCT oil.[01:06:31] Behind-the-scenes projects: Fusion, algae feed additives, meat alternatives.[01:08:32] Countries I wish I had visited earlier, and places I'd still like to see.[01:11:06] "Not yet" vs. "No" in early growth phases.[01:14:14] Post Coyote, do I have any future games in the works?[01:14:46] Over-ear vs. in-ear headphones for podcasting.[01:15:16] What's the uncrowded channel right now?[01:16:17] Recommendations for Dr. Mindy Pelz.[01:16:58] Robert Rodriguez and project juggling.[01:17:24] Fast neutron reactors and the Bugatti of ketones.[01:19:05] Extended family outings and Mahonk Mountain House.[01:20:31] NO BOOK meetup plans?[01:20:54] Parting thoughts.*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissPast guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, Margaret Atwood, Mark Zuckerberg, Peter Thiel, Dr. Gabor Maté, Anne Lamott, Sarah Silverman, Dr. Andrew Huberman, and many more.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.