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Today's show:*“KPop Demon Hunters” is one of the year's biggest smashes… AFTER Sony sold it off to Netflix for cheap! Hear about what went wrong with one of the year's worst deals…PLUS Grok is counting on SPEED to help it outpace rivals… How Rep. Ritchie Torres (D-NY) ran into trouble on the podcast circuit… Nvidia's big earnings report, and why everyone is watching that company in particular SO closely… PLUS a new Polymarket predicting the future of OpenAI!Timestamps:(0:00) How Sony missed out on “Kpop Demon Hunters”(10:15) .TECH: Say it without saying it. Head to get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.(11:20) Show continues…(13:59) Why some politicians struggle so much on podcasts(19:30) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit aws.amazon.com/startups/credits(20:53) Show continues…(30:24) Alphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at https://www.alpha-sense.com/twist(31:37) Grok is relying on SPEED to outpace rivals… and it's working(41:23) Are AI companies playing a mega-budget game of chicken?(42:31) Why everyone's watching Nvidia's earnings so closely(47:50) Jason says he'll NEVER go back to a non-AI browser(53:32) Polymarket: Is OpenAI going to release their own browser?Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(10:15) .TECH: Say it without saying it. Head to get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.(19:30) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit aws.amazon.com/startups/credits(30:24) Alphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at https://www.alpha-sense.com/twistReady to level up your AI collaborations?Head to www.claude.ai/twistYou can't do everything we're doing without a paid plan…But TWiST listeners get 50% off their first three months of Claude Pro.Just go to Claude dot AI Slash TWiST to get started.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
For our latest Strategy Session, Reid Hoffman and Kickstarter CEO Everette Taylor answer questions from entrepreneurs about how to build more resilient businesses. They share frameworks for taking smarter risks, finding co-founders, and more.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today's show:On a brand-new TWiST, Jason and Alex are asking why there are SO MANY note-taking AI apps?Plus another death has been linked to ChatGPT… is it too easy to get past chatbot guardrails? Why Donald Trump Jr. is joining Polymarket…. How the US Navy could catch up with its international rivals… AND should Apple just buy a big AI company to help them catch up?All that PLUS a visit from Colin Russ, whose viral H1B Visa thread might just inspire Jason to reach out to his good friend, Vice President JD Vance. Check out the full episode!Timestamps:(0:00) Intro, Jason's checking out Notion's new AI note taking app… is it time to cancel Granola?(06:57) How Google Gemini's new 2.5 Flash Image tool (formerly known as “nano-banana”) could change advertising(10:28) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(11:40) Show Continues…(17:50) Another death linked to ChatGPT… is it too easy to get around AI chatbot guardrails?(19:26) Vouched - Trust for agents that's built for builders like you. Check it out at http://vouched.id/twist(20:34) Show Continues…(28:10) Donald Trump Jr. invests in Polymarket and joins the board…(29:45) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(30:49) Show Continues…(33:30) How Jason thinks the US Navy could catch up with China and other rivals, with help from startups(40:01) Do Jason and Alex think Apple might REALLY buy a big, expensive AI company? Would that be admitting defeat?(45:57) Colin Russ (@ThaaatColin) tells us about his viral X thread and why he's worried about H1B visa fraud(55:32) Jason's solution for the H1B system, and a message for VP Vance.(01:08:25) Jason responds to Kara Swisher, who accused him sucking up to power(01:19:07) Jason responds to his old pal Sam Harris, who thinks he's loyal to the wrong peopleSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(10:28) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(19:26) Vouched - Trust for agents that's built for builders like you. Check it out at http://vouched.id/twist(29:45) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
Gains in the quality of America's K-12 education in the late 20th and early 21st century have largely plateaued—and , in several instances, reversed—in the last few decades. This week, Alpha School co-founder MacKenzie Price joins the show to discuss her fast-expanding network of AI-powered private schools, which she says represent the reform the system so badly needs. She explains why Alpha students learn core academics in two hours a day via a personalized learning platform—not human teachers—and then devote the rest of the school day to passion projects, life skills, and real-world learning. Plus, we hear from Alex, a high school senior at Alpha's Austin, TX location, about his experience. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/ Topics: 3:45 - Hellos and intros 4:12 – MacKenzie's path from Stanford psychology to Alpha Schools 6:11 – Updating traditional school systems with AI 7:46 – What makes Alpha Schools different 12:01 – The 2-Hour Learning model 15:40 – Key lessons from AI in classrooms 18:11 – AI supercharges students with the “four C's”: critical thinking, communication, collaboration, creativity 20:47 – Teacher-student connection and mentorship 21:54 – Scaling Alpha Schools & lowering costs 25:47 – AI-driven assessment & personalized learning plans 29:38 – Midroll 29:47 – Alex shares his experience as an Alpha School student and entrepreneur 34:19 – Challenges of scaling 36:09 – Student incentives & using Alpha currency to teach kids financial literacy 38:55 – Alpha students learn life skills & develop entrepreneurial projects 41:44 – GT School for highly accelerated learners 44:55 – “Future of Education” podcast highlights 47:16 – Teachers vs. guides & redefining expertise in education 49:21 – Using AI for public speaking & coaching 51:02 – Rapid fire questions Select mentions: Alpha School, AI-Driven Education Founded in Austin, Is Coming to More Cities — New York Times: https://www.nytimes.com/2025/07/27/us/politics/ai-alpha-school-austin-texas.html Future of Education Podcast: https://futureofeducationpod.com/ Berry: https://berryplush.com/ Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Each episode seeks to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.
AGI is coming. Reid Hoffman just wrote the book on how to prepare.According to Reid, every major tech breakthrough (the written word, the printing press, the telephone) triggered mass fear. But, contrary to our worries, new technology tends to enhance human agency—even more so, if you know how to use it well.Reid is the cofounder of LinkedIn, Inflection AI, and Manas AI; a partner at venture capital firm Greylock Partners; an early backer and board member of OpenAI; and an award-winning podcasterWe spent an hour talking about how to develop a compass for navigating AGI. Here are a few takeaways:Our sense of human agency is not just about external control but an internal stance—how we approach uncertainty & new tech is crucialIn new technology waves, NO blueprint or plan will have the right answers. Instead, adapting to new technology requires broad access, an experimental mindset, and flexibilityIn an AGI world most jobs will transform, not disappear—and how you can prepare with hands-on trial and errorHow certain social norms and ethics should change as AGI changes the landscape—like individual access to personal dataWhy now may be finally be the era where quantified self tools become valuable…and more, including everything in his new book Superagency, out this week.It was a pleasure to have him on the show for a second time. This is a must-watch for anyone who wants to help build a more human future with AI.If you found this episode interesting, please like, subscribe, comment, and share!Want even more? Sign up for Every to unlock our ultimate guide to prompting ChatGPT here: https://every-2.kit.com/ultimate-guide-to-prompting-chatgptIt's usually only for paying subscribers, but you can get it here for free.To hear more from Dan Shipper: Subscribe to Every: https://every.to/subscribe Follow him on X: / danshipperSponsor:Attio is the AI-native CRM built for the next era of companies. With Attio, setup takes minutes. Connect your email and calendar, and it instantly builds a CRM that mirrors your business. Go to https://www.attio.com/every to get 15% off on your first year.Timestamps:00:00:00 — Episode Start00:01:29 — Introduction00:02:50 — Patterns in how we've historically adopted technology00:07:02 — Why humans have typically been fearful of new technologies00:13:25 — How Reid developed his own sense of agency00:20:08 — The way Reid thinks about making investment decisions00:22:00 — Attio: Go to https://attio.com/every and get 15% off your first year on your AI-powered CRM.00:29:40 — AI as a "techno-humanist" compass00:35:30 — How to prepare yourself for the way AI will change knowledge work00:41:39 — Why equitable access to AI is important00:45:15 — Reid's take on why private commons will be beneficial for society00:47:23 — How AI is making Silicon Valley's conception of the "quantified self" a reality00:52:14 — The shift from symbolic to sub-symbolic AI mirrors how we understand intelligence01:03:29 — Reid's new book, SuperagencyLinks to resources mentioned in the episode:Reid Hoffman: @reidhoffmanSuperagency, Reid's newest book: https://www.superagency.ai/
Kevin J. Tracey, MD is president and CEO of the Feinstein Institutes for Medical Research at Northwell Health, a pioneer of vagus nerve research and author of the recent book, The Great Nerve: The New Science of the Vagus Nerve and How to Harness Its Healing Reflexes. This episode is brought to you by:Eight Sleep Pod Cover 5 sleeping solution for dynamic cooling and heating: EightSleep.com/Tim (use code TIM to get $350 off your very own Pod 5 Ultra.)AG1 all-in-one nutritional supplement: https://DrinkAG1.com/Tim (1-year supply of Vitamin D plus 5 free AG1 travel packs with your first subscription purchase.)Wealthfront high-yield cash account: https://Wealthfront.com/Tim (Start earning 4.00% APY on your short-term cash until you're ready to invest. And when new clients open an account today, you can get an extra fifty-dollar bonus with a deposit of five hundred dollars or more.) Terms apply. Tim Ferriss receives cash compensation from Wealthfront Brokerage, LLC for advertising and holds a non-controlling equity interest in the corporate parent of Wealthfront Brokerage. See full disclosures here.Timestamps:00:00 Tim's intro: why he dismissed vagus-nerve hype06:34 What the vagus nerve actually is, plus common myths11:31 Breaking news: FDA approval for SetPoint's RA implant + Kelly Owens's turnaround21:11 Inflammation 101: when healing turns harmful31:37 Bioelectronic medicine: from lab insight to real devices55:26 TNF, IL-1, and IL-6: immune drivers and what VNS modulates56:06 Exercise & recovery: vagal signals, IL-6, and adaptation56:30 Cold exposure & breathwork: sympathetic spike, parasympathetic payoff59:04 Chronic inflammation today: prevalence, diagnostics, and uncertainty59:53 Autoimmunity: genes, environment, infections01:01:08 Stress hormones, personality traits, and metabolic fallout01:05:41 VNS tech landscape: implants, focused ultrasound, and what's just TENS01:11:14 Ear maps, revisited: the real science behind auricular stimulation01:27:52 Ulf Andersson: auricular TENS, famotidine, and a depression turnaround01:36:48 Depression & inflammation: where VNS helps (and where it doesn't)01:41:38 Body-brain loop: how inflammation signals ride the vagus nerve01:42:56 Why VNS can lift mood: a working theory01:43:22 Ulf's setup: electrode placement and twice-daily routine01:44:37 Acupuncture, fertility, and plausible vagal links01:47:23 Chronic pain through an inflammation lens01:48:34 Neural “engrams”: how the brain can store inflammatory memories02:02:35 Cervical TENS vs. true VNS: mechanisms and open questions02:12:15 On stage with the Dalai Lama: blue energy and two vagus nerves02:16:55 Closing thoughts: self-care vs. medical devices, and what's next*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissPast guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, Margaret Atwood, Mark Zuckerberg, Peter Thiel, Dr. Gabor Maté, Anne Lamott, Sarah Silverman, Dr. Andrew Huberman, and many more.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
AI tools are disrupting all types of creative content, and Runway AI is a pioneer making major waves in Hollywood. It's partnering with the likes of Disney and Netflix to revolutionize production. Runway's co-founder & CEO Cristóbal Valenzuela joins Rapid Response to dissect the company's breakneck growth, the risks and responsibilities of AI tool makers, and how AI is redefining both business expectations and our notion of creativity. Cristóbal also reveals why he rebuffed advances from Meta for a highly lucrative acquisition, and how AI video is just a stepping stone to an entirely new media format — one more expansive and transportive than we can realistically comprehend today.Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today's show:On an upbeat and optimistic new TWiST, Jason and Alex are debating why any new innovation or technology gets hit with a wave of bitter cynicism.PLUS Jason defends the government taking shares of Intel, explains the importance of interoperability, and predicts how AirBnB's Joe Gebbia will upgrade the US government's website design.All that PLUS thoughts on the Netskope IPO, Perplexity offering publishers actual revenue share, a deep dive on the new AI-based PAC, thoughts on open-source LLMs, and much much much more.Timestamps:(0:00) Cynicism vs. Optimism and why Jason thinks cynics go after any interesting new technology(10:02) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist(11:04) Show Continues…(14:37) Why Jason supports the Intel deal but worries it will become a trend(20:46) Public - Take your investing to the next level with Public. Build a multi-asset portfolio and earn 4.1% APY on your cash—with no fees or minimums. Start now at public.com/twist.(22:00) Show Continues…(27:02) Is it hypocritical to oppose socialist grocery stores but support the Intel deal? Jason says NO.(29:41) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(30:58) What does xAI hope to get out of this OpenAI/Apple lawsuit? Jason and Alex theorize…(39:12) Why Jason thinks interoperability is so important and how App Stores OUGHT to work(41:12) How AirBnB's Joe Gebbia could potentially upgrade the US government's websites(49:27) What does Netskope do exactly? SASE?! Producer Claude explains…(58:32) Alex and Jason celebrate Perplexity rev sharing with publishers(01:10:02) Jason's thoughts on the Leading the Future PAC, and US AI policySubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(10:02) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist(20:46) Public - Take your investing to the next level with Public. Build a multi-asset portfolio and earn 4.1% APY on your cash—with no fees or minimums. Start now at public.com/twist.(29:41) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWISTGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
AI is not as new as we think, says Gary Rivlin, author of *AI Valley: Microsoft, Google, and the Trillion-Dollar Race to Cash in on Artificial Intelligence.* As our non-artificial guest on *The Resonance Test,* Rivlin tells host Barry Briggs that back in the 1950s, it was thought that AI was always right around the corner. There would be a gathering of technologists who said: “Give us 10 years and we'll have this thing largely solved.” Which meant, says Rivlin: “AI was ‘a decade away' for about 70 years.” Rivlin notes that recommendation engines and Google Translate have been operating for a while. “Google Translate has been around since 2015. That's AI, but no one really thinks of it as AI.” However, when ChatGPT strutted onto the scene, it was something else. Rivlin says: “We were talking to it. Suddenly: AI that you could converse with. It's a whole different beast.” The builders of that beast are his topic in *AI Valley.* Rivlin, who was a reporter for *WIRED* in the dot-com days, returns to his old beat to document the onset of the recent, fast-blooming AI spring. He and Briggs, a former CTO at Microsoft IT, bring years of history into the conversation to offer an assessment at this moment of peak AI in Silicon Valley. They talk, for instance, of Reid Hoffman. Briggs says, “He's the exception to the rule of nice guys finish last.” Rivlin zings back, calling Hoffman: “A billionaire you can root for” and adding “this lonely kid who wanted friends created LinkedIn, which connects the world.” Together they remember the dot-com days of irrational exuberance, getting-rich-by-selling-dog-food-online. “The problem was we tend to overestimate the short-term impact of a technology and underestimate the long term,” says Rivlin, adding we're seeing a similar sort of thinking with AI today. The pair reflect on how people used to joke about autocomplete. “I should have started thinking, ‘this could turn into sentences, this could turn into paragraphs, this could turn into dialogue,'” says Briggs. Rivlin notes that agents aren't “trustworthy” yet. He says that if an agent is going to “make material decisions, it really needs to be trustworthy.” In two, five, 10 years from now, “AI agents are going to be central to the work life of many, maybe perhaps most of us.” We trust that you'll be informed and entertained by this episode. Click on! Host: Alison Kotin Engineer: Kyp Pilalas Producer: Ken Gordon
Today's show:Terra's collapse, Powell's pivot, and OpenAI's explosive growth all collide in this TWiST deep dive.Do Kwon has pled guilty after Terra/Luna's $60B implosion, Fed Chair Powell hints at a September rate cut, and OpenAI has officially crossed $1B in monthly revenue (on a $12B run rate). Jason and Alex unpack what this means for founders, LPs, and the next wave of AI + crypto.They also cover Canva's $42B comeback, Anthropic's doubled $10B fundraise, and the brewing battle between Figma & Canva.Plus: Uber, Nuro & Lucid's $6B robotaxi push — and why drivers are already protesting in Wuhan & Boston.#Startups #Crypto #AI #VentureCapital #OpenAI #Anthropic #Canva #Figma #ThisWeekInStartupsTimestamps:(0:00) INTRO(01:15) Fed rate cut signals & market reaction(05:36) Jason's $400K in new fund bets(10:25) Miro - Help your teams get great done with Miro. Check out miro.com to find out how!(11:30) Show Continues…(16:22) Do Kwon & the Terra/Luna collapse(20:22) Bolt - Don't be left behind. Build apps quickly without knowing how to code with Bolt.new. Try it free at https://www.bolt.new/twist.(21:23) Show Continues…(29:43) Alphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at https://www.alpha-sense.com/twist(30:55) Show Continues…(36:14) OpenAI's $1B/month revenue run rate(42:13) Anthropic's $10B round & AI market sizing(51:31) Canva's $42B valuation & Figma comparisonSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(10:25) Miro - Help your teams get great done with Miro. Check out miro.com to find out how!(20:22) Bolt - Don't be left behind. Build apps quickly without knowing how to code with Bolt.new. Try it free at https://www.bolt.new/twist.(29:43) Alphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at https://www.alpha-sense.com/twistGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
Whether you're building a new product from scratch, growing your team, or trying to find product market fit, every part of scaling a business has one thing in common. It needs to be well designed. That's why we're headed back to school this week – and learning from Stanford d.school executive director Sarah Stein Greenberg. She reveals strategies for using human-centered design to improve everything from your product roadmap to your company culture.Greenberg's book: Creative Acts for Curious PeopleSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Dr. Jeffrey Goldberg is Professor and Chair of Ophthalmology and Director of the Byers Eye Institute at Stanford University, a leading scientist in the development and degeneration of the visual system from eye to brain, and a practicing ophthalmologist and surgeon.This episode is brought to you by: Gamma AI design partner for effortless presentations, websites, social media posts, and more: https://gamma.app (use code TIM at checkout for one month off on their annual plan)Helix Sleep premium mattresses: https://HelixSleep.com/Tim (27% off on all mattress orders)AG1 all-in-one nutritional supplement: https://DrinkAG1.com/Tim (1-year supply of Vitamin D plus 5 free AG1 travel packs with your first subscription purchase.)Timestamps:[00:00:00] Start.[00:05:30] How do you solve a problem like presbyopia?[00:08:34] The athletic benefits of training supranormal (better than 20/20) vision.[00:11:49] Indigenous eye drops and FDA-approved pilocarpine for presbyopia.[00:14:05] Understanding basic eye anatomy.[00:17:27] Exploring AREDS 2, CoQ10, ginkgo, vitamin B3, and other supplements for vision.[00:23:00] Visual training devices and psychedelic-prompted brain plasticity.[00:25:12] Thoughts on visual training effectiveness and motor action requirements.[00:28:29] Concussion rehabilitation and visual perception exercises.[00:32:36] Red light and violet light therapy for myopia and mitochondrial health.[00:36:07] Vision loss correlation with cognitive decline and depression.[00:39:36] Presbyopia progression and psychological dependence on readers.[00:41:15] Cognito Therapeutics headset for Alzheimer's treatment.[00:46:46] Glaucoma basics: neurodegenerative disease and risk factors.[00:48:53] Eye pressure variability and diurnal cycles.[00:50:02] Cannabis effects on eye pressure and compound isolation.[00:51:47] Stem cell research for vision restoration.[00:53:09] Anti-inflammatory effects and immune system role in eye diseases.[00:55:15] Gut microbiome connection to glaucoma in animal models.[00:58:43] Metabolic syndrome and GLP-1 receptor agonists.[01:00:50] Microbiome sharing and future therapeutic possibilities.[01:03:31] Dry eye treatment: preservative-free tears and serum drops.[01:08:43] Vision screening recommendations and UV protection.[01:11:22] Full-spectrum light benefits vs. UV exposure.[01:13:27] Paradigm shifts: irreversible vision loss becoming reversible.[01:17:18] Convergence of neuroscience advances and biotech investment.[01:21:58] Miraculous mitochondria: health, transplants, and three-parent babies.[01:26:24] My family history concerns and metabolic health screening.[01:29:26] Exercise's biggest gain: going from none to some.[01:33:03] Clinical trial participation resources and parting thoughts.*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissPast guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, Margaret Atwood, Mark Zuckerberg, Peter Thiel, Dr. Gabor Maté, Anne Lamott, Sarah Silverman, Dr. Andrew Huberman, and many more.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today's show:In this TWiST 500 double feature, Alex sits down with two breakout founders: Chalk's Marc Freed-Finnegan & Tollbit's Toshit Panigrahi!First, Chalk's CEO Marc Freed-Finnegan is tackling one of AI's biggest bottlenecks—data freshness. Instead of relying on stale batch jobs, Chalk delivers real-time pipelines for inference compute, automatically transpiling Python into C++/Rust so it can run blazing fast in production. Investors are calling it the ‘next Databricks'—and after hearing this convo, you'll see why.Then, Tollbit's CEO Toshit Panigrahi returns after raising a $24M Series A and signing up 1,400+ publishers. With RAG traffic exploding and robots.txt losing its teeth, their ‘bot paywall' could reshape how AI agents pay for the content they consume. Are we heading for a Spotify moment for data licensing?A must-watch if you care about the economics of AI, from data pipelines to publisher monetization.Timestamps:(0:00) Intro + sponsors(1:03) Alex tees up two Twist 500 interviews: Chalk & Tolbert(2:47) Why AI is shifting from training compute to inference compute(4:41) Data freshness & real-time inference explained(10:43) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(12:00) How Chalk transpiles Python into C++/Rust for speed(18:52) Chalk's business model, margins & $500M valuation(20:11) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(21:24) Show Continues…(28:02) Tollbit returns: $24M Series A & the rise of RAG bot traffic(30:37) .TECH: Say it without saying it. Head to get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.(31:41) Show Continues…(36:53) Robots.txt losing relevance & the case for bot paywalls(39:19)Publishers, AI agents & the future economics of the webSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(10:43) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(20:11) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(30:37) .TECH: Say it without saying it. Head to get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
A veteran Pulitzer Prize-winning journalist shadows the top thinkers in the field of Artificial Intelligence, introducing the breakthroughs and developments that will change the way we live and work. Artificial Intelligence has been “just around the corner” for decades, continually disappointing those who long believed in its potential. But now, with the emergence and growing use of ChatGPT, Gemini, and a rapidly multiplying number of other AI tools, many are wondering: Has AI's moment finally arrived? In AI Valley: Microsoft, Google, and the Trillion-Dollar Race to Cash In on Artificial Intelligence (Harper Collins, 2025), Pulitzer Prize-winning journalist Gary Rivlin brings us deep into the world of AI development in Silicon Valley. Over the course of more than a year, Rivlin closely follows founders and venture capitalists trying to capitalize on this AI moment. That includes LinkedIn founder Reid Hoffman, the legendary investor whom the Wall Street Journal once called, “the most connected person in Silicon Valley.” Through Hoffman, Rivlin is granted access to a number of companies on the cutting-edge of AI research, such as Inflection AI, the company Hoffman cofounded in 2022, and OpenAI, the San Francisco-based startup that sparked it all with its release at the end of that year of ChatGPT. In addition to Hoffman, Rivlin introduces us to other AI experts, including OpenAI cofounder Sam Altman and Mustafa Suleyman, the co-founder of DeepMind, an early AI startup that Google bought for $650 million in 2014. Rivlin also brings readers inside Microsoft, Meta, Google and other tech giants scrambling to keep pace. On this vast frontier, no one knows which of these companies will hit it big–or which will flame out spectacularly. In this riveting narrative marbled with familiar names such as Musk, Zuckerberg, and Gates, Rivlin chronicles breakthroughs as they happen, giving us a deep understanding of what's around the corner in AI development. An adventure story full of drama and unforgettable personalities, AI Valley promises to be the definitive story for anyone seeking to understand the latest phase of world-changing discoveries and the minds behind them. Learn more about your ad choices. Visit megaphone.fm/adchoices Support our show by becoming a premium member! https://newbooksnetwork.supportingcast.fm/new-books-network
As young people report feeling lonelier and less connected than ever, the dating app Hinge is driving its users into real life, human experiences. CEO Justin McLeod returns to Rapid Response to share how the platform is combating digital fatigue amongst users, as well as navigating the risks and opportunities of AI in online dating. McLeod also explores Hinge's recent collaboration with renowned psychologist Esther Perel, and offers insider tips to find that special someone in the chaos of modern romance. Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today's show:We're back with two insightful new TWiST founder interviews.First up: Dean Leitersdorf of Decart tells us about squeezing maximum productivity out of your GPUs. But it's not all talk: he also shows us the incredible open world model that can magically transform live footage.THEN! Jason and Alex chat with Syncere AI founder Aaron Tan about Lume, his robotic lamp device that went viral for folding laundry. Hear why Aaron thinks the future of robotics is not necessarily humanoid, and all about his future plans for the Lume arms.Timestamps:(0:00) Alex introduces our TwiST 500 interviews(02:27) TWiST 500 Interview #1: Dean Leitersdorf, CEO and Founder of Decart(04:37) Setting out to build a “kilo-corn,” a trillion dollar company(06:27) How making AI much faster opens up a world of new opportunities(09:48) OpenPhone - Streamline and scale your customer communications with OpenPhone. Get 20% off your first 6 months at https://www.openphone.com/twist(11:00) Why Dean thinks chatbots are the interface of the future(17:24) How Decart builds and trains its models more efficiently (and for less money)(20:01) Netsuite - Download the ebook CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twist(21:14) Show Continues…(24:36) Interview #2: Aaron Tan of Syncere AI(25:13) Behind-the-scenes of that viral Lume “robot lamp folding laundry” video(30:23) Stripe Startups - Stripe Startups offers early-stage, venture-backed startups access to Stripe fee credits and more. Apply today on stripe.com/startups.(31:25) Moving beyond laundry: what else these Lume robots do?Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(09:48) OpenPhone - Streamline and scale your customer communications with OpenPhone. Get 20% off your first 6 months at https://www.openphone.com/twist(20:01) Netsuite - Download the ebook CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twist(30:23) Stripe Startups - Stripe Startups offers early-stage, venture-backed startups access to Stripe fee credits and more. Apply today on stripe.com/startups.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
Ask Me How I Know: Multifamily Investor Stories of Struggle to Success
You've tried everything — the habits, the routines, the resets. But the patterns keep coming back. This episode breaks down why intensity won't get you there — and how to shift with integration instead.You've tried all the right things — early wakeups, new planners, strict morning routines — only to find yourself burned out, frustrated, and falling back into old patterns. In this episode, Julie Holly breaks down the root of sustainable change: integration over intensity.You'll learn how your nervous system, neuroplasticity, and spiritual grounding all play a role in rewiring your life at the identity level. Plus, the story of Reid Hoffman's pivot from chaos at PayPal to calibrated consistency at LinkedIn.We'll link prior episodes for deeper context in the show notes.What We Cover in This Episode:• Why your brain resists rigid habit plans• How over-optimization sabotages long-term growth• What Reid Hoffman learned from the early PayPal chaos• How neuroplasticity works under conditions of safety• The spiritual foundation for integration (Phil. 1:6, NLT)• Vagal tone and why your nervous system needs margin• The difference between short-term sprints and sustainable pace• How to move beyond intensity and embrace integrationToday's Micro-Recalibration:Pick one default response you uncovered in Episode 31 or 32.Ask:• Where does this response show up most often?• What would pausing for 5 seconds look like?• How can I integrate a new response gently — not perfectly?You're not behind. You're becoming.If this episode gave you language you've been missing, please rate and review the show so more high-capacity humans can find it. Explore Identity-Level Recalibration→ Follow Julie Holly on LinkedIn for more recalibration insights → Schedule a conversation with Julie to see if The Recalibration is a fit for you → Download the Misalignment Audit → Subscribe to the weekly newsletter → Join the waitlist for the next Recalibration cohort This isn't therapy. This isn't coaching. This is identity recalibration — and it changes everything.
As we gear up for our 2025 Masters of Scale Summit, we're revisiting one of the stellar on-stage conversations that happened at the 2024 event. Hear Rocket Companies' Dan Gilbert and Detroit Mayor Mike Duggan reveal how their unique public-private partnerships have transformed the struggling city into a growing hub for everything from tech companies to electric vehicle manufacturing. Note: this conversation was recorded in October of 2024, before Duggan announced he would not seek another term as mayor and is instead running for governor of Michigan as an independent.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Our guests this week: Adam Brotman and Andy Sack, co-authors of the book AI First: The Playbook for a Future-Proof Business and Brand. Brotman was Starbucks’ chief digital officer and later co-CEO of J.Crew. Sack is a founder, investor, and longtime advisor to tech leaders. Together, they run Forum3, a company that helps brands rethink loyalty and customer engagement. For their book, they interviewed experts including Bill Gates, Sam Altman, Reid Hoffman and Ethan Mollick, and spent time with companies that have had early success with AI implementation. We talk about their "holy-shit" moment with Sam Altman, how Moderna achieved 80% employee participation through AI contests, the CEO who supercharged sales by using AI to analyze call transcripts, and what leaders should actually be doing to roll out AI within their organizations. With GeekWire co-founder Todd Bishop.See omnystudio.com/listener for privacy information.
It's a Friday TWiST and Jason and Alex are FIRED UP about this internal Meta doc laying out appropriate vs. inappropriate AI behavior… You won't BELIEVE with what Zuck approves for 8-year-old users.PLUS… AI job displacement is HERE, at least in the Big Apple… Jason's getting kind of paranoid about the surveillance state… AI remains frothier than ever through new Cohere and Cognition rounds… and why we're dubious that Sam Altman REALLY plans to spend $1 trillion on OpenAI data centers.It's all happening on a brand-new This Week in Startups. Give it a click!Timestamps:(0:00) Intro - How Opendoor became a meme stock(06:58) When companies have less value than cash on hand… what gives?(10:23) - (11:24) Bolt - Don't be left behind. Build apps quickly without knowing how to code with Bolt.new. Try it free at https://www.bolt.new/twist(19:13) New York's not adding jobs… Jason and Alex dig in and offer some theories.(20:25) - (21:30) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(26:56) AI job displacement is HERE and it's happening, folks…(30:05) Why Jason predicts unemployment will be 20% higher 1 year from today… add it to the TWiST Calendar(30:24) - (31:37) Alphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at https://www.alpha-sense.com/twist(33:02) Wait, Meta AI is having “sensual” chats with children? WHY?(40:00) Will there be fallout to the Meta exposé? Legal? Staffing? Otherwise?(47:47) AI remains frothier than ever with new Cohere and Cognition rounds.(52:33) Sam Altman says he's going to spend $1 trillion on data centers… Jason's dubious.Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(10:23) Bolt - Don't be left behind. Build apps quickly without knowing how to code with Bolt.new. Try it free at https://www.bolt.new/twist(20:25) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(30:24) Alphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at https://www.alpha-sense.com/twistGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
From humble beginnings selling vacuums on late night informercials, SharkNinja has grown to a 6 billion dollar a year business. CEO Mark Barrocas joins host Jeff Berman to reveal how the company keeps coming up with hits like the Ninja Creami, why “educated consumers” are the backbone of their business, and how they're navigating the shifting winds of tariffs.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today's show:We're back with another all-star VC roundtable discussion.Joining Jason are Dave McClure of Practical VC, NVNG's Grady Buchanan, and Tomasz Tunguz of Theory VC. Together, they're having a deep insider discussion of the state of venture, secondary markets, running funds of funds, the legacy of Lina Khan, the difficulty of recruiting, and why the pendulum has potentially swung in founders' favor.Timestamps(0:00) INTRO, The origins of Practical VC and how secondary funds work.(05:44) So… how does Dave decide what to BUY?(09:27) Melanie - Companies are staying private longer… Is this good for fund managers?(10:02) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(11:18) Show Continues…(14:17) We've all heard about unicorns but… what about centaurs?!(16:19) Jacob - Are VC marks… bullsh*t?! How long until your LPs should see DPI? The panel debates.(17:22) Jacob - Is Jason too hard on Lina Khan? Dave says VCs created the problem!(20:07) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit aws.amazon.com/startups/credits(21:30) Show Continues…(30:01) Public - Take your investing to the next level with Public. Build a multi-asset portfolio and earn 4.1% APY on your cash—with no fees or minimums. Start now at public.com/twist.(31:16) Show Continues…(31:34) When it's time to embed an expert into a struggling startup(34:15) How investing in SO MANY COMPANIES gave Dave a trove of data(40:33) Sometimes VCs have to be the “voice of reality”…(45:53) Are stock buybacks the best use of capital?(49:29) Jacob - The End of the ZIRP Era meets the Dawn of the AI Era(51:04) Why running your business on debt, not equity, requires tough choices(58:23) When you need to “take the medicine” on returns and live to fight another day.(01:11:17) Is Grady actively seeking managers that have shown a demonstrated ability to produce liquidity?(01:13:24) Dave says the pendulum has swung into founders' favor.(01:20:25) Dave teases his new secondary podcast, “Trading Places”!Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(10:02) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(20:07) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit aws.amazon.com/startups/credits(30:01) Public - Take your investing to the next level with Public. Build a multi-asset portfolio and earn 4.1% APY on your cash—with no fees or minimums. Start now at public.com/twist.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
How can we take digitally-empowered democracy straight out of science fiction into reality? This week, Reid and Aria are joined by two digital democracy pioneers, Audrey Tang and Divya Siddarth. Audrey Tang is a cyber ambassador-at-large and former inaugural Minister of Digital Affairs for Taiwan. Their pioneering initiatives like the Sunflower Movement, g0v, and vTaiwan have fought misinformation and influenced policy decisions. Audrey is also a senior research fellow for the Collective Intelligence Project, co-founded and directed by Divya Siddarth. Divya leads projects worldwide that give voice to the public in building better AI. Audrey and Divya have spent years investigating how people converge on uncommon ground and how to beat polarization. They discuss the power of collective input and collaboration to create a cycle of collective intelligence. Plus, how AI tools—informed by public input—can enhance governance, digital life, and bring out the best in all of us. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/ Topics: 3:07 - Hellos and intros 3:38 - Audrey and Divya's partnership backstory 7:06 - Challenges and surprises with AI in governance 10:19 - What problems do CIP's projects aim to solve? 13:04 - Breakthroughs in collective intelligence 15:08 - Fighting polarization in the age of social media 16:50 - Capitalizing on innate collective intelligence 18:51 - The difference between collective intelligence and democracy 20:33 - Design principles for democracy-forward AI 23:30 - Involving the public in AI model building 26:18 - Midroll 28:32 - Bringing Taiwan's civic wins worldwide 30:41 - Radical transparency in digital tools 35:18 - Why aren't Taiwan's initiatives landing in the U.S. 38:09 - Creating digital twins 39:52 - Reid and Aria's outlook on AI and democracy relations 42:04 - Who would Reid delegate AI centralization to? 45:05 - Rapid-fire Select mentions: Plurality by E. Glen Weyl, Audrey Tang, and Community Global Dialogues — The Collective Intelligence Project Alignment Assemblies — The Collective Intelligence Project “Anthem” by Leonard Cohen A Half Built Garden by Ruthanna Emrys The Dispossessed: An Ambiguous Utopia by Ursula K. Le Guin Terra Ignota series by Ada Palmer Taiwan's Digital Minister Knows How to Crush Covid-19: Trust | WIRED What Could BG Be? Engaged California How the Sunflower movement birthed a generation determined to protect Taiwan Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Each episode seeks to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.
Zoom out from continuing tariff turmoil and Trump's recent attacks on the Fed and the Bureau of Labor Statistics, and you'll see a broader new economic order is forming. Political economist and Brown University professor Mark Blyth joins Rapid Response to reveal why outdated models still underpin much of our economic understanding, and what we still misunderstand – and underestimate – about China. Blyth also shares why the Democrats struggle to craft an engaging story about the economy, why it's so hard to predict a recession, and what Brown's recent settlement with the Trump Administration tells us about higher education's need to pivot from its reliance on federal funding.Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today's show:On an all-new Monday TWiST, Lon joins Jason and Alex to talk about a whole bunch of stories at the intersection of tech, business, and pop culture.First up, is GPT Psychosis real? And if so, what are the warning signs that your loved ones have been ONESHOTTED.Then, why did Jason get so upset at the NY Times piece about Mark Zuckerberg's Palo Alto compound?PLUS we're discussing Trump's export fees on AMD and Nvidia, Jason's pitch for why the president should work more closely with Congress, a new tool in the search for rare-earth minerals, just how many self-driving trucks are on Chinese roads today, and much much more!Timestamps:(0:00) INTRO, Why Jason hated the NYT story about Mark Zuckerberg's compound.(09:54) Vouched - Trust for agents that's built for builders like you. Check it out at http://vouched.id/twist(11:14) Show continues…(19:54) Coda - Empower your startup with Coda's Team plan for free—get 6 months at https://www.Coda.io/twist(21:01) Show continues…(27:25) GPT Psychosis: Is it real and how widespread is it?(29:13) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist(30:16) Show continues…(45:45) What it means to get “One-Shotted”: is Sam Altman doing this on purpose?(53:56) Jason says working multiple jobs at once is STEALING… is that fair?(01:04:53) Are Trump's Chinese export fees for AMD and Nvidia a justified licensing process? Or a shakedown?(01:09:22) Jason's pitch for working closer with Congress, and why Alex has concerns about clarity(01:12:02) PolyMarket: Will tariffs generate >$250b in 2025?Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(09:54) Vouched - Trust for agents that's built for builders like you. Check it out at http://vouched.id/twist(19:54) Coda - Empower your startup with Coda's Team plan for free—get 6 months at https://www.Coda.io/twist(29:13) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twistGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
What if your tools shared context like your team does?This week on Grit, Shishir Mehrotra shares how the Coda and Grammarly collaboration unlocks context as a “superpower,” reflects on his early days at Google and YouTube, and hints at a future where tools anticipate intent and amplify how we work.He also shares how this paves the way for agent-based workflows and AI-native communication, beginning with Superhuman's email experience.Guest: Shishir Mehrotra, co-founder of Coda and CEO of GrammarlyConnect with ShishirXLinkedInChapters: 00:00 Trailer01:24 Introduction02:09 Zoo vs safari12:02 A TV ahead of its time21:25 Product decisions31:25 The data behind the algorithm37:26 The AI native productivity suite48:06 Agents are digital humans57:55 Pressure trade-off1:12:50 Insulated from judgment1:25:19 Who Grammarly is hiring1:25:51 What “grit” means to Shishir1:29:30 OutroMentioned in this episode: YouTube, Ray William Johnson, Spotify, Twitch, MTV, Chris Cox, Facebook, TikTok, Google TV, Centrata, Google Chrome, Android, Gmail, Microsoft, Super Bowl, Mosaic, Panasonic, Sony, Susan Wojcicki, Rishi Chandra, Apple TV, Amazon Firestick, Comcast, LoudCloud (Opsware), Quest Communications, AT&T Southwestern Bell, Salar Kamangar, Patrick Pichette, Eric Schmidt, OpenAI ChatGPT, Google Gemini, Mark Zuckerberg, Meta Platforms, Sundar Pichai, Larry Page, Sergey Brin, Hamilton, Reid Hoffman, Sam Altman, Tesla, Waymo, Airtable, Notion, Max Lytvyn, Alex Shevchenko, Superhuman, Duolingo, Luis von Ahn, Khan Academy, MrBeast, Facebook Messenger, Snap (Snapchat), WhatsApp, Google+, Meta LLaMa, Satya Nadella, Tim Cook, Daniel GrossConnect with JoubinXLinkedInEmail: grit@kleinerperkins.comLearn more about Kleiner Perkins
Today's show:Jason and Lon recorded a Thursday night special edition, so no Alex this time, but still lots to talk about.First up, Jason thinks it's time for Tim Apple to exit the stage in lieu of a product obsessive innovator. Speaking of new products, GPT-5 is here and the hosts are… not exactly blown away. Are we in the midst of the AI trough of despair?PLUS we're talking Ripple's acquisition of Rail, Donald Trump's new AI chatbot, Bumble's new direction, Airbnb's potential paths forward and MUCH MUCH MORE.Timestamps:(0:00) Why Jason thinks Apple lacks innovation (plus a look back at his 2019 thoughts)(08:54) Sentry - New users get 3 months free of the Business plan (covers 150k errors). Go to http://sentry.io/twist and use code TWIST(09:54) Show continues…(20:10) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(21:18) Is GPT-5 coming for Lovable and Bolt?(29:42) Alphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at AlphaSense.com/Twist.(30:55) Show continues…(35:05) Ripple buying Rail, and why sometimes regulations are GOOD for companies(43:28) Is Ripple about to become the MicroStrategy of XRP?(47:48) Truth Social AI is perplexing, powered by Perplexity(53:27) Should people be using ChatGPT for therapy? What do you think? How does that make you feel?(01:04:42) Anthropic's Dario Amodei recalls his greatest haters(01:11:04) Bumble but… for friendship?(01:12:20) DoorDash's crazy growth, and the guys discuss who should buy AirbnbSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(08:54) Sentry - New users get 3 months free of the Business plan (covers 150k errors). Go to http://sentry.io/twist and use code TWIST(20:10) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(29:42) Alphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at AlphaSense.com/Twist.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
When Rick Shadyac Jr. took over as CEO of the fundraising organization responsible for St. Jude Children's Research Hospital, it was bringing in about 600 million a year. The recently retired leader joins host Jeff Berman to reveal how he built a fundraising machine that is now approaching 3 billion per year, and how that money will have a global impact on kids with cancer. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today's show:It's a brand-new PACKED episode of TWiST. Jason and Alex welcome guest Zach Dive of Adam.new, to tell us why he made a deepfake AI ad starring Jason and the All-In besties.PLUS a rundown of the biggest tech and startup news of the day, including Disney's decision to sunset Hulu, OpenAI's new open-weight models, the Cloudflare vs. Perplexity feud, Uber's newly-announced stock buyback, China's Luckin Coffee coming to Manhattan, and much much more!Timestamps:(0:00) Luckin Coffee hits NYC… along with COMMUNISM?!(09:15) Is China taking on major American brands on PURPOSE?(10:16) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(11:29) Show Continues…(20:17) CLA - Get started with CLA's CPAs, consultants, and wealth advisors now at https://claconnect.com/tech(21:30) Show Continues…(26:02) RIP HULU: Why Disney is sunsetting the iconic app.(28:37) Nostracanis Returns: Jason's 2017 Disney vs. Netflix predictions came true(30:24) .TECH - Say it without saying it. Head to www.get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.(31:28) Show Continues…(35:39) Zach Dive of Adam.new joins to tell us about making a viral deepfake ad starring JCal and the Besties(44:10) Zach shares thoughts on AI and copyright, and why it's a problem for the “big dogs,” not him… yet(48:12) Jason wants to wet his beak… but is there room in the Adam.new seed round?(53:07)OpenAI's new models are open-WEIGHT; how that's different from open-source.(58:36) Do Nvidia and Apple devices NEED kill switches and backdoors? Why it's such a tough question.(01:02:10) GPT-5 arrives TOMORROW?!(01:03:31) Cloudflare vs. Perplexity… let them fight?Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(10:16) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(20:17) CLA - Get started with CLA's CPAs, consultants, and wealth advisors now at https://claconnect.com/tech(30:24) .TECH - Say it without saying it. Head to www.get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
This is a very special episode for me. My brand-new card game, COYOTE, created in collaboration with Elan Lee and Exploding Kittens, is here. It is available in ~8,000 locations worldwide, including Walmart, Target, Amazon, and many others. Learn more: https://coyotegame.com.This episode is brought to you by: Gamma AI design partner for effortless presentations, websites, social media posts, and more: https://gamma.app (use code TIM at checkout for one month off on their annual plan) Shopify global commerce platform, providing tools to start, grow, market, and manage a retail business: https://shopify.com/tim (one-dollar-per-month trial period)Wealthfront high-yield cash account: https://Wealthfront.com/Tim (Start earning 4.00% APY on your short-term cash until you're ready to invest. And when new clients open an account today, you can get an extra fifty-dollar bonus with a deposit of five hundred dollars or more.) Terms apply. Tim Ferriss receives cash compensation from Wealthfront Brokerage, LLC for advertising and holds a non-controlling equity interest in the corporate parent of Wealthfront Brokerage. See full disclosures here.Timestamps (will be updated): 00:00 Intro 05:21 The Journey to Creating a Game05:51 The Creative Process Behind Coyote17:16 The Importance of Constraints in Creativity35:04 The Toronto Sprint41:02 The Evolution of Coyote: From Concept to Prototype47:36 Game Design Principles and Recommendations51:53 Introduction to 'Don't Shoot the Dog'53:25 Simplifying Game Design58:55 Playtesting and Iteration01:08:10 Finding the Sweet Spot in Game Difficulty01:14:35 The Success of 'Hurry Up Chicken Butt'01:22:26 Testing and Feedback Process01:34:49 Pitching to Big Retailers01:36:19 Designing the Perfect Game Box01:36:31 Testing and Validating Game Designs01:41:23 The Road to Retail Success01:43:51 Keys to a Successful Line Review01:44:29 The Role of Agents and Publishers02:07:56 Crowdfunding and Self-Publishing02:19:56 Understanding Game Publishing Deals02:27:40 Common Pitfalls in Game Packaging and Marketing02:38:39 Navigating Retail and Distribution Challenges02:47:25 Final Thoughts and a Tantalizing Offer*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissPast guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, Margaret Atwood, Mark Zuckerberg, Peter Thiel, Dr. Gabor Maté, Anne Lamott, Sarah Silverman, Dr. Andrew Huberman, and many more.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
As the Trump Administration ramps up mass deportations, the American Business Immigration Coalition is advocating for policy reform. Rebecca Shi leads the organization made up of 1,400 current and former CEOs, trade group leaders and more, who heavily rely on an immigrant workforce. Hear how uncertainty over immigration has disrupted daily business and hit the bottom line, as well as the carve-outs and clarity that big employers like Lowe's, Tyson Foods and others seek for the long-term.Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today's show:Jason and Alex are running down the biggest tech, startup, and business stories of the day on a brand-new Monday TWIST.Which countries are leading the AI race, based on academic papers? Why Jason thinks covert agencies are spying on Meta's superintelligence team. Lina Khan's taking a victory lap on the Figma IPO but what did she REALLY accomplish during her Biden administration tenure? PLUS, why we're bringing Founder University to the MENA region.All that and MORE on a packed episode! Find out why we're the #1 podcast for startups and founders.Timestamps:(0:00) Why Jason is attending more TV poker tournaments(4:02) Did you know Founder University is headed to MENA? Calling all Riyadh founders.(10:01) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(11:27) Show Continues…(19:52) Oracle - Try OCI and save up to 50% on your cloud bill at https://www.oracle.com/twist(21:01) Why Jason doesn't think Lina Khan deserves her Figma IPO victory lap.(23:17) Jason thinks Figma is overpriced: how quickly could a rival build a competitor?(27:53) For an investor, there's a huge difference between a home run and a GRAND SLAM.(30:42) Monarch Money - Get 50% Off Monarch Money, the all-in-one financial tool at www.monarchmoney.com/TWIST(31:55) Show Continues…(40:59) Why Jason thinks covert agencies are spying on Meta's global Superintelligence Team…(50:43) Which countries are leading the AI race in terms of research? Producer Claude helps with the answer.(57:12) Fact-checking the viral BYD TikTok: can their self-driving cars really drive themselves off the ship?(59:52) Jason and Alex check out some of their dream carsSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:10:01) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(19:52) Oracle - Try OCI and save up to 50% on your cloud bill at https://www.oracle.com/twist(30:42) Monarch Money - Get 50% Off Monarch Money, the all-in-one financial tool at www.monarchmoney.com/TWISTGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
In this week's episode of the Rich Habits Podcast, Robert Croak and Austin Hankwitz sit down with Reid Hoffman. Reid was part of the "PayPal Mafia" from back in the late-90s. He sold PayPal to eBay for $1.5 billion in 2002. A few months later, Reid co-founded LinkedIn. Microsoft acquired LinkedIn for $26B in 2016. This interview was special. Reid is an incredible bright, kind, and thoughtful human being. We're so grateful to have been able to host him on the show! ---
Today's show:Alex is back with three more awesome interviews with founders on the bleeding edge of innovative tech.Dr. Hon Weng Chong walks us through the basics of biological computing and Cortical Labs' first-ever commercial computer running on living human cells.Turing founder Jonathan Siddarth unpacks the secrets of LLM benchmarking, and explains why even our most advanced tests need to get much much harder right away.Finally, Mercor founder Brendan Foody on how AI is about to reinvent the hiring process, and marrying the effectiveness of recruiters with the ease of online job boards.It's three — count 'em, three — can't miss TWiST interviews guaranteed to make you smarterTimestamps:(0:00) OpenAI's GPT-5: When is it coming out? Is it going to be TOO smart?(08:06) Cortical Labs' Hon Weng Chong on the electric connection between neuroscience and machine learning(10:20) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(11:27) Show Continues…(15:17) The extreme difficulty of going from the lab to a shippable product(20:00) .TECH: Say it without saying it. Head to www.get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.(21:05) Show Continues…(28:15) Why data is a factor of time(29:52) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit aws.amazon.com/startups/credits(31:16) Show Continues…(42:44) Turing CEO Jonathan Siddarth explains why it's so important to keep benchmarking our LLMs(47:24) What it means when a model “saturates” a test, and why benchmarks need to get HARDER(50:22) What happens with the LLMs can answer all of our smartest questions?(53:44) AI Agents train in gyms? Wait, really?(01:01:33) Coding teaches models how to think, and more training mysteries don't understand(01:03:11) Brendan Foody from Mercor explains the “matching problem” that makes hiring such a pain(01:07:02) How Mercor combines a job board's distribution with the value of a recruitment agency(01:10:49) Brendan recalls building his first AI interviewer in his college dorm(01:20:16) Mercor has the opposite of a retention problem and crazy growthSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(10:20) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(20:00) .TECH: Say it without saying it. Head to www.get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.(29:52) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit aws.amazon.com/startups/creditsGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
When Ross Martin and Kern Schireson blended their companies in 2020 to form Known, they knew they wanted to throw out the old rule book about how to succeed in marketing. Now, they're scaling fast and producing jaw-dropping results for clients. They join host Jeff Berman to reveal how their success relies on innovative AI — and kind humans — working together in new ways. Plus, advice for how to get great results from marketing that doesn't break the bank.Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
What can public libraries teach us about finding and sharing trustworthy information in the age of AI? How can—and should—AI build upon the technology that is books? This week, Reid and Aria head to the New York Public Library in Manhattan for a conversation with the storied institution's president and CEO, Tony Marx. They explore the function of libraries in the age of AI, debate the future of work, and discuss what it looks like for civic institutions to embrace transformative technology without sacrificing core values. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/ Topics: 2:54 - Hellos and intros 3:23 - Tony's studies and work in South Africa 5:25 - Taking a job as president of Amherst College 8:43 - Eliminating library fines and fees 9:23 - Visiting the Inwood Library 13:30 - Determining what gets digitized 16:20 - New media 17:42 - AI's function for libraries 23:08 - Navigating hallucinations 27:57 - AI becoming our epistemology 29:36 - Technological advancements at the NYPL 33:54 - Future of work and human costs of AI 39:41 - Can AI close the educational gap? 42:43 - Trust, reliability, and AI 45:18 - Rapid-fire questions Select mentions: Possible | Kim Stanley Robinson on the future of civilization: https://www.youtube.com/watch?v=B6OlJbPDpyc Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Each episode seeks to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.
Cloudflare recently made headlines with breakthrough technology that stops AI companies from scraping online content with impunity. That's major impact, since the company is involved in more than 20 percent of all online traffic. Cloudflare co-founder and CEO Matthew Prince joins Rapid Response to share how the new tools are poised to dramatically impact AI firms, publishers, and the future of the internet. Prince also takes listeners inside the state of cyberwarfare in the age of AI, and why Trump's immigration policy could erode US business dominance for years to come.Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today's show:SYDNEY SWEENEY'S AMERICAN EAGLE AD DIVIDES OUR PANEL!PLUS WHAT STARTUPS CAN LEARN FROM THE VIRAL ASTRONOMER RESPONSEJason, Alex, and Lon are looking at some of the biggest media stories of the day before returning to their favorite topic, tech. Tune in for deep dives on IMAX's new AI film festival, Figma's big IPO and much more!*Timestamps:(0:00) Jason and Alex kick off the show!(3:45) Lon's joining Alex and Lon to discuss the controversial Sydney Sweeney genes/jeans ad(7:20) A look at the polarizing takes on this jeans ad.(10:10) OpenPhone - Streamline and scale your customer communications with OpenPhone. Get 20% off your first 6 months at https://www.openphone.com/twist(11:46) Hear the verdict from Jason, self—proclaimed Chairman of the Interwebs(16:42) Alex points out the economic impact of the controversy(20:26) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist(21:25) Back to the show!(26:35) Paltrow's Astronomer ad, meme-processing and the ideal way to change the conversation(30:04) Vouched - Trust for agents that's built for builders like you. Check it out at http://vouched.id/twist(31:28) Back to the show!(36:48) Netflix and the growing controversy around AI's role in filmmaking(42:53) IMAX/Runway collaboration and Hollywood's shifting attitude toward AI(47:34) Everything that went wrong with the Tea App(54:27) Why Jason thinks app stores should ban “anonymous” forms and message boards(1:04:19) Figma upped its IPO price… what does it mean for the return of liquidity? And is this too high or fairly priced?(1:07:53) Paul Graham says you shouldn't drop out of college to work on a startup… Why Thiel Fellows disagree*Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcp*Follow Lon:X: https://x.com/lons*Follow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelm*Follow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanis*Thank you to our partners:(10:10) OpenPhone - Streamline and scale your customer communications with OpenPhone. Get 20% off your first 6 months at https://www.openphone.com/twist(20:26) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist(30:04) Vouched - Trust for agents that's built for builders like you. Check it out at http://vouched.id/twist*Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarland*Check out Jason's suite of newsletters: https://substack.com/@calacanis*Follow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com*Subscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
How do I learn to delegate? When is it time to expand? How can I find the right partners? Hear two iconic leaders – Sarah Robb O'Hagan and Elan Lee – take on real questions from early stage founders in our Masters of Scale Strategy Session. Robb O'Hagan has led iconic brands like Gatorade, Equinox and Exos. Lee is the founder and CEO of the game company Exploding Kittens.Don't miss our next free, virtual event on Aug 14 with Reid Hoffman and Kickstarter CEO Everette Taylor. Register now: mastersofscale.com/auguststrategysessionMasters of Scale Strategy Sessions are presented by Capital One Business.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Now on Spotify Video! Crafting a winning business offer is one of the most critical and often overlooked steps in building a profitable venture. Without a validated offer, even the most passionate entrepreneurs risk building a business no one needs. In this episode of the Passion to Profit series, presented by Intuit, Hala Taha breaks down the building blocks of an irresistible offer. You'll hear from powerhouse entrepreneurs like Alex Hormozi, Amy Porterfield, and Russell Brunson on how to master the art of giving people exactly what they want. In this episode, Hala will discuss: (00:00) Introduction (00:00) Market Research: The Key to Starting a Business (00:00) How to Position Your Offer for Success (00:00) The Power of Value Selling (00:00) The Psychology of Pricing (00:00) How to Test and Refine Your Business Offer Intuit, the maker of TurboTax and QuickBooks, is expanding its world-class network of tax and bookkeeping experts. Whether you want a side hustle or a career pivot, Intuit offers the tools to help you grow as an entrepreneur. Their supportive team, mission-driven culture, and Intuit Academy—a free, self-paced training platform—mean you're set up to succeed, even if you're just getting started. Learn more or apply now at intuit.com/expert. Sponsored By: Intuit, The Maker of TurboTax and QuickBooks. Learn more or apply now at intuit.com/expert. Resources Mentioned: YAP E199 with Alex Hormozi: youngandprofiting.co/TheValueEquation YAP E244 with Amy Porterfield: https://youngandprofiting.co/QuitMyJobBuiltaBusiness YAP E302 with Cal Fussman: youngandprofiting.co/PowerofQuestions YAP E155 with Kelly Roach: youngandprofiting.co/ConvictionMarketing YAP E312 with Russell Brunson: youngandprofiting.co/Million-DollarSalesFunnel YAP E337 with Adam Schafer: youngandprofiting.co/MindsetEntrepreneursWhoWin YAP E150 with Bob Burg: youngandprofiting.co/Go-GiverSalesStrategy YAP E318 with Rudy Mawer: youngandprofiting.co/PlaybookforScalingBrands YAP E106 with Josh Kaufman: youngandprofiting.co/LaunchingaBusinessSideHustle YAP E332 with Reid Hoffman: youngandprofiting.co/ScalingValuableCompaniesFast Active Deals - youngandprofiting.com/deals Key YAP Links Reviews - ratethispodcast.com/yap YouTube - youtube.com/c/YoungandProfiting LinkedIn - linkedin.com/in/htaha/ Instagram - instagram.com/yapwithhala/ Social + Podcast Services: yapmedia.com Transcripts - youngandprofiting.com/episodes-new Disclaimer: This episode is a paid partnership with Intuit. Sponsored content helps support our podcast and continue bringing valuable insights to our audience. Entrepreneurship, Entrepreneurship Podcast, Business, Business Podcast, Self Improvement, Self-Improvement, Personal Development, Starting a Business, Strategy, Investing, Sales, Selling, Psychology, Productivity, Entrepreneurs, AI, Artificial Intelligence, Technology, Marketing, Negotiation, Money, Finance, Side Hustle, Startup, Mental Health, Career, Leadership, Mindset, Health, Growth Mindset, Entrepreneurship, Entrepreneurship Podcast, Business Podcast, Startup, Passive Income, Online Business, Solopreneur, Founder, Networking
NYU Stern School of Business professor Suzy Welch has designed a framework – “Becoming You” – to help you figure out how to build a career that aligns with your values. She joins host Jeff Berman to dig into what happens when those values are in conflict and how to navigate the fundamental misalignment between Gen Z and the rest of the workforce.To learn more about the “Becoming You” book and values quiz, go to https://lnk.to/suzywelch!MastersOfScale See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today's show:TWiST is back with a three more hugely insightful (and also fun!) founder interviews.First up, Trey Holterman from Tennr tells us why getting in to see a specialist is so time consuming, and how AI is making the entire health care industry more streamlined.THEN Gill Verdon from Extropic AI unpacks deterministic vs. probabilistic computing, and how thermodynamics can make everything from robots to VR more effective.FINALLY, Tyler Denk from our fav newsletter platform Beehiiv walks us through their future roadmap, and explains why they're adding new features SO OFTEN.It's a packed episode full of fresh insights for founders. Check it out!Timestamps:(0:00) Alex opens the show with the venture/investor POV on TWiST 500 med tech company Tennr(03:38) Tennr CEO/co-founder Trey Holterman on the inefficiencies facing medical specialists and why patients are actually “leads”(10:20) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(11:44) Paid Promo END(14:05) How Tennr trained an AI model to comb through clinical histories, medical files, and doctor's notes(18:19) Why automation matters for Tennr but it's not the WHOLE story(20:03) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(21:10) Paid Promo END(22:57) The incredible cultural influence of the Dominos Pizza Tracker(29:57) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit aws.amazon.com/startups/credits(31:20) Gill Verdon from Extropic on the difficulty of keeping up with the demand for compute and the “scaling law”(35:37) Thermodynamic regimes, the differences between deterministic vs. probabilistic computing, and why this matters(41:31) Gill on expanding Extropic's research team while keeping a close eye on burn(52:17) Will robots ever be FULLY autonomous, with no ties or connections back to the fleet? Gill says… maybe!(58:52) Beehiiv's Tyler Denk on hitting $20M ARR while ALSO scaling up their ad network(01:00:35) The practical and psychological importance of product velocity and shipping as many features as possible(01:01:57) Why Tyler says “Substack vs. Beehiiv” is analogous to “Amazon vs. Shopify”(01:08:08) How much larger can the newsletter market still GROW? (And the promise of moving beyond content and into marketing emails.)(01:09:00) Why Tyler thinks the strongest publishers own their audience and distributionSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(10:20) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(20:03) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(29:57) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit aws.amazon.com/startups/creditsGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanis
It's been one of the most consequential weeks ever in the media business, from CBS' Stephen Colbert cancellation, and Trump's lawsuit against the Wall Street Journal, to Congress clawing back more than $1 billion in funding from PBS and NPR. Axios' Media Correspondent Sara Fischer joins Rapid Response to cut through the conspiracy theories and unpack what it all means from here.Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Today's show:WHY DOES @SUBSTACKINC NEED $100M IN NEW FUNDING?HOW DO THEY PLAN TO STAY AHEAD OF @BEEHIIV?Jason and Alex are debating the future of indie publishing on an all-new TWiST, considering the future of these rival platforms, plus Patreon and more.PLUS they're digging into Lovable's latest raise and what it says about the current economics of vibecoding, surveying the automated driving landscape in light of Uber's new agreement Lucid and Euro, explaining Jason's “meme processing” theory of internet humor, AND looking ahead to Christopher Nolan's IMAX epic “The Odyssey.”Join us for the longest-running and most in-depth podcast on Earth for startup founders.Timestamps:(0:00) Intro - Everyone is getting hyped for Nolan's “The Odyssey”(03:49) “Meme Processing,” the Astronomer saga, and giving people a little grace(10:07) INBOUND - Use code TWIST10 for 10% off your General Admission ticket at https://www.inbound.com/register (Valid thru 7/31)(18:49) Substack vs. Patreon vs. Beehive: Who ya got?!(19:43) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(29:39) Public - Take your investing to the next level with Public. Build a multi-asset portfolio and earn 4.1% APY on your cash—with no fees or minimums. Start now at public.com/twist.(37:58) Lovable, vibecoding, and how much AGI might one day be worth(01:00:36) Uber's Lucid/Nuro deal: Alex did the math(01:08:03) Is autonomous driving about to change EVERYTHING? Jason says… YES.Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(10:07) INBOUND - Use code TWIST10 for 10% off your General Admission ticket at https://www.inbound.com/register (Valid thru 7/31)(19:43) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(29:39) Public - Take your investing to the next level with Public. Build a multi-asset portfolio and earn 4.1% APY on your cash—with no fees or minimums. Start now at public.com/twist.All investing involves the risk of loss, including loss of principal. Brokerage services for US-listed, registered securities, options and bonds in a self-directed account are offered by Public Investing, Inc., member FINRA & SIPC. Public Investing offers a High-Yield Cash Account where funds from this account are automatically deposited into partner banks where they earn interest and are eligible for FDIC insurance; Public Investing is not a bank. Cryptocurrency trading services are offered by Bakkt Crypto Solutions, LLC (NMLS ID 1890144), which is licensed to engage in virtual currency business activity by the NYSDFS. Cryptocurrency is highly speculative, involves a high degree of risk, and has the potential for loss of the entire amount of an investment. Cryptocurrency holdings are not protected by the FDIC or SIPC.Alpha is an experimental AI tool powered by GPT-4. Its output may be inaccurate and is not investment advice. Public makes no guarantees about its accuracy or reliability—verify independently before use.*Rate as of 7/18/25. APY is variable and subject to change.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.com
The board game CATAN has sold 45 million copies worldwide since Klaus Teuber invented it 30 years ago. It's Reid Hoffman's favorite board game for business leaders. He sat down with brothers Benjamin and Guido Teuber, who now run the business of CATAN, to talk about how they've kept the game evolving, why its core philosophy of strategic collaboration still resonates, and what entrepreneurs can learn from trading sheep for wood.Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Dan Shipper is the co-founder and CEO of Every. With just 15 people, Every publishes a daily AI newsletter, ships multiple AI products, and operates a million-dollar-a-year consulting arm—all while their engineers write virtually zero code. It's the most radical example of AI-first operations, and Dan is a prolific writer who has become a leading voice on how AI is transforming the way we build and work.Learn:1. Why Dan thinks AI won't steal jobs en masse—and may actually reshore many jobs to the U.S.2. The most underrated AI tool for non-programmers3. An inside look at Every's AI-first workflow4. Why every company needs an “AI operations lead”5. How Dan's team uses an arsenal of AI agents (Claude, Codex, “Friday,” “Charlie”) in parallel, treating each AI like a specialist with unique strengths6. Why generalists will thrive in an AI-first world, as rigid job titles blur and everyone becomes a “manager” of AI tools7. Dan's playbook for making any company AI-first—from the CEO setting the example, to hosting internal prompt-sharing sessions, to upskilling teams on AI tools—Brought to you by:CodeRabbit—Cut code review time and bugs in half. Instantly: https://www.coderabbit.ai/DX—A platform for measuring and improving developer productivity: https://getdx.com/lennyPostHog—How developers build successful products: https://posthog.com/lenny—Transcript: https://www.lennysnewsletter.com/p/inside-every-dan-shipper—Where to find Dan Shipper:• X: https://x.com/danshipper• LinkedIn: https://www.linkedin.com/in/danshipper/• Podcast: https://every.to/podcast—Where to find Lenny:• Newsletter: https://www.lennysnewsletter.com• X: https://twitter.com/lennysan• LinkedIn: https://www.linkedin.com/in/lennyrachitsky/—In this episode, we cover:(00:00) Welcome and introduction(04:04) Hot takes on AI and job reshoring(07:06) The power of Claude Code for non-coders(14:35) The future of AI in business operations(18:45) AI's role in enhancing human skills(22:26) The evolution of AI tools and their applications(25:40) Building an AI-first company(29:50) Innovative AI operations and team dynamics(35:35) Dan's AI stack(41:26) Compounding engineering(48:29) The impact of AI on learning and development(50:10) Accelerating career growth with AI(51:36) Revolutionizing code review and workflow(53:07) The importance of coding knowledge(57:26) Building AI-driven products(01:02:01) Innovative fundraising strategies(01:08:45) Consulting and AI adoption in companies(01:17:01) The allocation economy and future skills(01:20:12) The value of generalists in the AI age(01:24:07) Lightning round and final thoughts—Referenced:• Claude Code: https://www.anthropic.com/claude-code• Gemini CLI: https://blog.google/technology/developers/introducing-gemini-cli-open-source-ai-agent/• Microsoft Copilot: https://copilot.microsoft.com/• Cursor: https://www.cursor.com/• Base44: https://base44.com/• Solo founder, $80M exit, 6 months: The Base44 bootstrapped startup success story | Maor Shlomo: https://www.lennysnewsletter.com/p/the-base44-bootstrapped-startup-success-story-maor-shlomo• The rise of Cursor: The $300M ARR AI tool that engineers can't stop using | Michael Truell (co-founder and CEO): https://www.lennysnewsletter.com/p/the-rise-of-cursor-michael-truell• Plato's Argument Against Writing: https://fs.blog/an-old-argument-against-writing/• From ChatGPT to Instagram to Uber: The quiet architect behind the world's most popular products | Peter Deng: https://www.lennysnewsletter.com/p/the-quiet-architect-peter-deng• Granola: https://www.granola.ai/• Tobi Lutke's post on X about context engineering: https://x.com/tobi/status/1935533422589399127• Tobi Lütke's leadership playbook: Playing infinite games, operating from first principles, and maximizing human potential (founder and CEO of Shopify): https://www.lennysnewsletter.com/p/tobi-lutkes-leadership-playbook• Every: https://every.to/• Cora: https://www.cora.computer/• Sparkle: https://makeitsparkle.co/• Spiral: https://spiral.computer/• Lex: https://lex.page/• Nathan Baschez on LinkedIn: https://www.linkedin.com/in/nbashaw/• Kate Lee on LinkedIn: https://www.linkedin.com/in/kate-lee-506768/• Katie Parrott on LinkedIn: https://www.linkedin.com/in/katieparrott/• Animalz: https://www.animalz.co/• Rachel Woods on X: https://x.com/rachel_l_woods• Nityesh Agarwal on LinkedIn: https://www.linkedin.com/in/nityeshaga• Claude Opus 4: https://www.anthropic.com/claude/opus• Codex: https://openai.com/index/introducing-codex/• Superwhisper: https://superwhisper.com/• Wispr Flow: https://wisprflow.ai/• Notion: https://www.notion.com/• Kieran Klaassen on LinkedIn: https://www.linkedin.com/in/kieran-klaassen/• Friday: https://www.friday.run/• Charlie: https://www.gocharlie.ai/product/ai-agents/• Avengers: https://en.wikipedia.org/wiki/Avengers_(Marvel_Cinematic_Universe)• Alex Duffy on LinkedIn: https://www.linkedin.com/in/alex-d/• Danny Aziz on LinkedIn: https://www.linkedin.com/in/dannyaziz/• Dia: https://www.diabrowser.com/• Reid Hoffman's website: https://www.reidhoffman.org/• Starting Line VC: https://www.startingline.vc/• Walleye Capital: https://walleyecapital.com/• At This $10 Billion Hedge Fund, Using AI Just Became Mandatory: https://every.to/podcast/at-this-10-billion-hedge-fund-using-ai-just-became-mandatory• Reflexive AI usage is now a baseline expectation at Shopify: https://x.com/tobi/status/1909251946235437514• Klarna CEO Sebastian Siemiatkowski on Getting AI to Do the Work of 700 Customer Service Reps: https://www.sequoiacap.com/podcast/training-data-sebastian-siemiatkowski/• The Pin Factory: https://www.adamsmithworks.org/pin_factory.html• Deadwood on HBO: https://www.hbo.com/deadwood• Joel Spolsky on X: https://x.com/spolsky• Jason Fried's website: https://world.hey.com/jason• Jason Fried challenges your thinking on fundraising, goals, growth, and more: https://www.lennysnewsletter.com/p/jason-fried-challenges-your-thinking• Sam Harris's website: https://www.samharris.org/• Bill Simmons on X: https://x.com/billsimmons—Recommended books:• War and Peace: https://www.amazon.com/War-Peace-Vintage-Classics-Tolstoy/dp/1400079985• Anna Karenina: https://www.amazon.com/Anna-Karenina-Leo-Tolstoy/dp/0143035002• Playing and Reality: https://www.amazon.com/Playing-Reality-Routledge-Classics-86/dp/0415345464• The Death of Ivan Ilyich: https://www.amazon.com/Death-Ivan-Ilyich-Leo-Tolstoy/dp/1468014315• A Swim in a Pond in the Rain: https://www.amazon.com/Swim-Pond-Rain-Russians-Writing/dp/1984856022• The Master and His Emissary: The Divided Brain and the Making of the Western World: https://www.amazon.com/Master-His-Emissary-Divided-Western/dp/0300245920/—Production and marketing by https://penname.co/. For inquiries about sponsoring the podcast, email podcast@lennyrachitsky.com.Lenny may be an investor in the companies discussed. To hear more, visit www.lennysnewsletter.com
Today's show:Jason and Alex tackle a full tech and business news docket on today's show, including Jason's big SF trip with Launch Accelerator's 34th cohort, some peculiar social media posts from VC Geoff Lewis, a look inside the HUGE seed rounds being commanded by early-stage AI startups, crunching the numbers on how much compute data centers need to sell before they're profitable, Polymarket asks who will be the next CEO of X and MUCH MUCH MORE.Join us for the longest-running and most in-depth podcast on Earth for startup founders.Timestamps:(00:00) INTRO(01:31) Jason's in SF with LAUNCH Accelerator cohort 34… His take on the mood in Silicon Valley.(07:52) Odd X posts from Bedrock Capital's Geoff Lewis… what does it all mean?(10:09) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist(14:44) Ask JCal: What founders can do to guard their own mental health and well-being(20:17) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(22:04) Thinking Machines Lab set a new record for a seed round: what's going on with these MEGA deals?(28:51) Alex (and Kabir from LAUNCH's research team) investigated the economics of data centers… just HOW MUCH can you make from selling compute? And how long does it TAKE to turn a profit?(30:52) Bolt - Don't be left behind. Build apps quickly without knowing how to code with Bolt.new. Try it free at https://www.bolt.new/twist.(37:09) Superintelligence vs. AGI: Jason thinks we're still more than 2-3 years away…(39:52) GPx is not a traditional VC fund: here's what industry vet Brian Singerman is up to(49:37) The importance of setting your own corporate culture… before it gets set for you!(58:15) Polymarket has ideas for the next X CEO… see where Jason ranks on the list!(01:03:18) Reddit wants to know… Do investors judge founders negatively who rely on lots of AI tools?Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(10:09) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist(20:17) Northwest Registered Agent. Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(30:52) Bolt - Don't be left behind. Build apps quickly without knowing how to code with Bolt.new. Try it free at https://www.bolt.new/twist.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916
After 16 years as Editor-in-Chief of Harvard Business Review, Adi Ignatius is handing the role over to a new leader, and he joins Rapid Response for a more-than-an-exit interview. A longtime friend and colleague of host Bob Safian, Ignatius shares some of the most critical lessons he's learned in decades of covering business and leadership, as well as dissecting the most hot button issues today — from Elon Musk's conflicting priorities, to AI's impact on media, and what Americans most misunderstand about China. Plus, Ignatius takes us inside Harvard's response to Trump's attacks, and why such stories are leaving business leaders in fear of speaking out against the government. Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
Van Leeuwen Ice Cream is one of the fastest growing dessert brands in the country. It's known for its seriously delicious classic flavors and its wacky collaborations. (Kraft Mac and Cheese ice cream, anyone?) Co-founder and CEO Ben Van Leeuwen talks with Jeff Berman to reveal how it grew from his love of simple ingredients and driving an ice cream truck as a teenager into a rapidly scaling company with about 2,000 employees.Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.
In this special episode, my friend—and fan-favorite guest—Dr. Peter Attia takes the mic as guest host. Peter sits down with legendary trader John Arnold, widely considered the greatest energy trader of all time. Today, through his foundation Arnold Ventures, John applies the same rigorous thinking to some of America's toughest social challenges—criminal justice reform, healthcare policy, and K–12 education, to name just a few. This interview originally aired on Peter's excellent podcast The Drive. You can check it out at PeterAttiaMD.com, or subscribe to The Drive wherever you get your podcasts.This episode is brought to you by:Vanta trusted compliance and security platform: https://vanta.com/tim ($1000 off)Eight Sleep Pod Cover 5 sleeping solution for dynamic cooling and heating: EightSleep.com/Tim (use code TIM to get $350 off your very own Pod 5 Ultra.)Wealthfront high-yield cash account: https://Wealthfront.com/Tim (Start earning 4.00% APY on your short-term cash until you're ready to invest. And when new clients open an account today, you can get an extra fifty-dollar bonus with a deposit of five hundred dollars or more.) Terms apply. Tim Ferriss receives cash compensation from Wealthfront Brokerage, LLC for advertising and holds a non-controlling equity interest in the corporate parent of Wealthfront Brokerage. See full disclosures here.Timestamps:[00:00:00] Start.[00:05:37] Peter Attia's intro: who is John Arnold?[00:08:38] John's background, upbringing, and early entrepreneurial tendencies.[00:21:16] John's time and rise at Enron.[00:33:40] Characteristics that made John an exceptional natural gas trader and how they translate to his philanthropic work.[00:41:10] The collapse of Enron.[00:46:46] The success of John's hedge fund, and his early interest in philanthropy.[01:02:03] The infamous 2006 trade that brought down Amaranth Advisors.[01:08:28] John's analytical prowess and emphasis on fundamentals.[01:15:13] The decision to become a full-time philanthropist and the founding of Arnold Ventures.[01:25:03] Education — John's quest to fundamentally change K-12 education.[01:30:36] Strategic philanthropy — preventing problems by attacking root causes and creating structural change.[01:37:50] The criminal justice system — structural changes needed to address mass incarceration, policing practices, and recidivism.[01:55:07] Re-imagining prisons to reduce recidivism.[02:02:27] US health care policy — John's focus on drug prices, and the severe consequences of not making system changes.[02:20:00] Climate change — the bipartisan role of John's foundation.[02:23:52] Advice for young adults interested in philanthropy.[02:30:52] Parting thoughts.*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissPast guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, Margaret Atwood, Mark Zuckerberg, Peter Thiel, Dr. Gabor Maté, Anne Lamott, Sarah Silverman, Dr. Andrew Huberman, and many more.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.