Podcast appearances and mentions of Reid Hoffman

How do you create authentic partnerships to build scale? In this archival episode, Reid Hoffman talks with the iconic entrepreneur and Shark Tank star Daymond John about how he built FUBU from scratch. Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today's show:*Zach Dell of Base Power joins us at the top of today's show to talk about building batteries in Austin, that $1 billion investment, and why an “all of the above” energy strategy is the only way forward.PLUS Jason and Alex's thoughts on that Tesla non-upside down car announcement, growing resentments toward AI datacenters, Chinese robots actually going on sale, Tim Cook's potential Apple exit, xAI's Nvidia agreement and MUCH MORE.Timestamps:(00:02:10) A MAJOR GUEST! Zach Dell of Base Power joins us from the top of the show.(00:03:31) The basics of Base Power's business model: the best electron is the cheapest electron(00:08:38) Zach teases Base's new, time-saving approach to battery installation(00:10:32) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist(00:18:12) How Base's grid can help drive down overall energy prices(00:21:17) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(00:30:12) Sentry - New users get 3 months free of the Business plan (covers 150k errors). Go to http://sentry.io/twist and use code TWIST(00:36:20) Tesla did not announce an upside fan car… Oh well…(00:44:27) Buy your Chinese robot TODAY on Walmart dot com? Or not!(00:48:12) Is Tim Apple EXITING Apple? Who's next?(00:59:22) ANOTHER mega-deal? Now xAI is circling a Nvidia investment…Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twistSquarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWISTSentry - New users get 3 months free of the Business plan (covers 150k errors). Go to http://sentry.io/twist and use code TWISTGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

How can AI really help advance medicine? Should patients and care teams be seeking second opinions from LLMs? This week, Reid and Aria sit down with physician-scientist Dr. David Fajgenbaum, who repurposes existing drugs to save lives—including his own. David shares his journey from receiving last rites as a young medical student to co-founding Every Cure, a nonprofit using AI to come up with ways existing drugs can be repurposed to treat every disease and every patient possible. On this special episode, filmed live in New York City, David, Reid, and Aria explore the circuit of hope, action, and impact that drives medical discovery; the technical and ethical challenges around accelerating AI in healthcare; “agent optimization” as the new “search engine optimization;” and what a future of faster diagnoses and treatment could look like. The result is a conversation about resilience, innovation, and unlocking cures that are already within our reach. For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/  Topics: 3:00 - Hellos and intros 3:29 - A promise to his mother and the origin of AMF 6:23 - From grief support to medical school 9:18 - Near-death experiences and founding a research network 14:38 - What kept David going at death's door 16:19 - Discovering a potential treatment and testing it on himself 19:42 - Why drug repurposing is a faster, cheaper complement to drug discovery 22:14 - Co-founding Every Cure and scaling discovery with AI 25:20 - Demo: Building MATRIX and how the algorithm makes predictions 28:41 - Breast cancer and Lidocaine as a case study 30:07 - Why human review is essential in AI for medicine 34:08 - Car exhaust fumes example and FDA pathways 37:31 - Reid's surprise million-dollar donation for Every Cure compute 39:24 - What AI can unlock across healthcare 41:46 - Building an impact team to close the repurposing loop 47:32 - Improving systemic incentives for generics 54:58 - FDA approval pathways and label change challenges 57:21 - Three life-saving repurposing stories 1:02:20 - Rapid-fire questions Select mentions:  Hidden Potential by Adam Grant Chasing My Cure by Dr. David Fajgenbaum Every Cure  David's TED Talk: https://youtu.be/sb34MfJjurc?si=GcVleWHZuJ9MqLgS Manas AI Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Each episode seeks to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.

In this encore episode of Rapid Response, we chart OLIPOP's surging popularity. As Gen Z and millennials ditch sugary sodas, OLIPOP is leading the prebiotic beverage trend, sparking the likes of Coca-Cola and PepsiCo to enter the fray. OLIPOP's co-founder, CEO, and formulator, Ben Goodwin, shares how the brand is navigating the turbulence of rapid growth and rising competition, what leadership lessons he's had to embrace along the way, and whether healthy soda is actually healthy or just a TikTok-fueled fad.Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today's show:*How many weirdly circular mega-deals is OpenAI going to sign this year?On a new TWiST, Jason and Alex consider OpenAI's latest agreement with AMD, how the biggest American companies keep trading cash and chips back and forth, and whether or not the entire AI economy might be a house of cards.PLUS what kind of fan/leafblower tech is Tesla working on… what can Jevons Paradox tell us about the AI landscape… how easy is it to master games in the YC Arena… and WHY has NASA never built a base on the moon? We're asking the TOUGH QUESTIONS so you don't have to, only on the #1 tech podcast, “This Week in Startups.”Timestamps:(0:00) Jason and Alex open the show discussing hunting and traditional Texas meat exchanges(2:16) ANOTHER weirdly circular OpenAI mega-deal? How many mega-deals can one company MAKE?(3:50) Are all these “bizarre” OpenAI deals creating a house of cards?(10:00) Stripe Startups - Stripe Startups offers early-stage, venture-backed startups access to Stripe fee credits and more. Apply today on stripe.com/startups.(20:00) Oracle - Try OCI and save up to 50% on your cloud bill at https://oracle.com/twist⁠⁠⁠(21:14) Is the Tesla Roadster 2 coming soon? Or maybe a leaf blower?!(22:00) Datacenters in space! Is it getting crowded up there?(26:22) Why no moon base yet? Jason demands a moon base.(27:00) We're playing games in the YC Arena… Can Jason guess which pitches got accepted?(30:00) Coda - Empower your startup with Coda's Team plan for free—get 6 months at https://www.Coda.io/twist(32:00) How Jason picks companies to invest in, based on a few signals and metrics(04500) We found out what Figure's bots are actually doing for BMW(53:00) Sharpies figured out how to make their pens here in the US… who's next?!(57:00) Could ChatGPT really replace Deloitte consultants? Considering the latest controversy…(01:03:29) It's another Gamma Pitch: Welcome Ryan Yannelli of NextVisit AI, which helps therapists take notesSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Stripe Startups - Stripe Startups offers early-stage, venture-backed startups access to Stripe fee credits and more. Apply today on stripe.com/startups.Oracle - Try OCI and save up to 50% on your cloud bill at https://oracle.com/twist⁠⁠⁠Coda - Empower your startup with Coda's Team plan for free—get 6 months at https://www.Coda.io/twistGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

Today's show:Is Sora not just a copyright-killer but a TikTok-killer? Hear our review!The “This Week in Startups” team has been playing around inside OpenAI's viral app, which just hit #1 in the iOS Store. See all of Lon's creations, explore the land beyond the Uncanny Valley, and find out why the hottest new social app could stand to be a bit more social.PLUS Brave surpasses 100M MAUs… why Jason would sell ALL his OpenAI shares right away, Apple pulls the ICEBlock app from the App Store, AND how one founder hacked his local coffee shop to network and even get face time with a few VCs! It's all happening of a fast-paced Friday TWiST.Timestamps:(0:00) Why Jason started an Executive Training program at LAUNCH(05:17) Perplexity's Comet browser is now FREE to use; Jason unpacks their strategy(10:02) Monarch Money - Get 50% Off Monarch Money, the all-in-one financial tool at www.monarchmoney.com/TWIST(13:42) PLUS browser/search engine Brave passed 100M MAUs!(17:44) How a founder “hacked” his local coffee shop(20:06) Alphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at https://www.alpha-sense.com/twist(21:35) You need to make it EASY for people to give you feedback!(25:41) A look at the leanest startups around and how companies are doing more with less(30:11) LinkedIn Ads: Start converting your B2B audience into high quality leads today. We'll even give you a $100 credit on your next campaign. Go to http://LinkedIn.com/ThisWeekinStartups to claim your credit.(30:38) Why Jason would sell ALL his OpenAI shares right away!(38:56) Lon stops by to review the Sora app; the good, the bad, and the remixes!(48:45) Apple pulled the ICEBlock app… is this a free speech issue?(56:11) A new startup wants to fight gov't corruption… and keep a share of the proceedsSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Monarch Money - Get 50% Off Monarch Money, the all-in-one financial tool at www.monarchmoney.com/TWISTAlphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at https://www.alpha-sense.com/twistLinkedIn Ads: Thanks to our partner @LinkedInMktg. Start converting your B2B audience into high quality leads today. We'll even give you a $100 credit on your next campaign. Go to http://LinkedIn.com/ThisWeekinStartups to claim your credit.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

A daily quote to inspire the mind, gratitude to warm the soul, and guided breathing to energize the body. Quote: If you are not embarrassed by the first version of your product, you've launched too late.' - Reid Hoffman. Gratitude: All my five senses Guided Breathing: Equal Breathing. Visit TheDailyRefresh.com to share your unique piece of gratitude which will be featured on an upcoming episode, and make sure to watch the tutorial of how to make The Daily Refresh part of your Alexa Flash Briefings! Call to action: If you're ready to accomplish your #1 goal in 100 days, visit TheFreedomJournal.com and you'll be on your way. Use promo code 'refresh' as a thank you for listening to The Daily Refresh.

This week, the boys sling hot takes like baristas slinging lattes, diving into HR tech, AI, and corporate shenanigans with their signature wit. Kicking things off, they set the stage with a vibe check, chuckling over the wild ride of recruitment tech while side-eyeing the economic chaos of startups chasing venture capital like kids chasing ice cream trucks. No military leadership talk here, but they roast corporate missteps with the gusto of drill sergeants. The spotlight lands on JuiceBox, an AI-powered recruiting tool that snagged $36 million, including a $30 million Sequoia-led Series A. Chad's jazzed, calling it the “Capri Sun of HR tech” for its catchy name and $10 million revenue rocket. He wonders if they'll build a platform or get gobbled up in an acquisition faster than you can say “merger margarita.” Joel, the grumpy cat of the duo, sniffs history repeating, comparing JuiceBox to 2010s sourcing flops like Entelo. “Build fast, sell faster, or get squashed by LinkedIn,” he grumbles, predicting a big-tech beatdown. Next, they geek out over AI agents revolutionizing recruitment. Chad raves about Hackajob's agents that dig through applicant databases like treasure hunters, saving cash and recruiter sanity. Joel dreams of Chrome's new free Gemini AI turning browsers into job-search genies, scaring HR tech vendors like a horror flick. Chad warns, “Free? You're the product, kids!” as they lament job scams and hope AI security saves the day. LinkedIn's new Learning Career Hub gets a roasting—Chad calls it a “half-baked LinkedIn loaf” compared to slick competitors like Degreed. Joel likens it to Apple's VR headset: a panicked hedge against being left behind. They also torch Reid Hoffman's claim that work-life balance is a “red flag,” with Chad snapping, “Want me to work like a CEO? Pay me like one!” Joel laughs it off as Silicon Valley hot air, like a CEO dropping truth bombs after one too many kombuchas. Ford's CEO Jim Farley's $5 million pledge to train 15,000 workers by 2026 gets a collective eye-roll. Chad calls it “couch cushion change,” comparing it to Apple and Tesla's billion-dollar China training sprees. “Farley's begging for government handouts like a kid at a candy store,” he scoffs. Joel agrees, noting it's chump change next to a Super Bowl ad, and both warn U.S. companies are losing the EV race to China's manufacturing muscle. Finally, a Waymo self-driving car's illegal U-turn leaves cops stumped—no driver, no ticket! Chad, fresh off a Spanish speeding ticket by camera, wonders why the U.S. can't keep up with “Star Trek-level” tech. Joel predicts local governments will milk Google for fines to fund football fields. With automation on the rise, they're all in—just don't expect Robocop to sort it out anytime soon. Chapters 00:00 - Introduction 02:21 - Reflections on Current Events and Military Leadership 05:19 - Job Market Insights and Economic Concerns 09:13 - Cultural Commentary and Sports Events 16:11 - Tech Innovations in Recruitment 22:56 - Closing Thoughts and Future Outlook 25:06 - Evolving Market Strategies 27:13 - The Role of Agents in Recruitment 31:00 - Google's AI Integration and User Behavior 40:10 - LinkedIn's Challenges and Opportunities 46:32 - Ford's Workforce Development and EV Challenges 52:26 - Accountability in Autonomous Vehicles

Chomps co-founders Rashid Ali and Pete Maldonado had an unusual side hustle: selling meat sticks online. The co-founders join host Jeff Berman to reveal the phone call from Trader Joe's that changed everything, how they used lessons from failed startups, and how they built Chomps into a snack empire.Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Bulwark Capital https://KnowYourRiskPodcast.comHear directly from Zach Abraham as he shares insights in this FREE “Back To Basics” Webinar, TODAY at 3:30 Pacific.  Register now at Know Your Risk Podcast dot com. Bizable https://GoBizable.comUntie your business exposure from your personal exposure with BiZABLE.  Schedule your FREE consultation at GoBizAble.com today. Renue Healthcare https://Renue.Healthcare/ToddYour journey to a better life starts at Renue Healthcare. Visit https://Renue.Healthcare/Todd Alan's Soaps https://www.AlansArtisanSoaps.comUse coupon code TODD to save an additional 10% off the bundle price.Bonefrog https://BonefrogCoffee.com/toddThe new GOLDEN AGE is here!  Use code TODD at checkout to receive 10% off your first purchase and 15% on subscriptions.LISTEN and SUBSCRIBE at:The Todd Herman Show - Podcast - Apple PodcastsThe Todd Herman Show | Podcast on SpotifyWATCH and SUBSCRIBE at: Todd Herman - The Todd Herman Show - YouTubeEpisode Links:Terry Moran on Trump: “It's an administration of trolls, led by trolls… because we're a nation of trolls now”WATCH: Jon Ossoff admits that he knowingly lied to the nation about Joe Biden's cognitive decline because beating President Trump was more important to him. Georgia, your Senator lied to you—  because he cares more about Democrats having power than our state's best interests.Jay Inslee - “who is antifa?” Soros and Reid Hoffman are targets of investigation for funding radical left wing organizations‘50501' is a name you might not know right now, but must learn ASAP…WHITEHOUSE EO: “Countering Domestic Terrorism and Organized Political Violence.”These are not revolutionaries. These are all regular leftists you see every day, outright advocating for murder.BREAKING: UK government makes Digital IDs mandatory: 'You will not be able to work in the United Kingdom if you do not have a digital ID, it's as simple as that.'Years have passed, but the vision remains unchanged—and more chilling than ever. A clip of WEF founder Klaus Schwab recounts a discussion with the mayor of Los Angeles. In it, he fantasizes about a 2030 where the city is "private car-driven free," with highways converted into parks. This was never a fleeting comment. It was an early blueprint.

Today's show:Sora 2 will generate a video of whatever you like and respects no IP (unless they opt out)On a brand new TWiST, Jason and Alex check out Sora 2, the latest text-to-video app from TWiST 500 mainstays OpenAI, and look at some of the video videos that have already emerged from the TikTok-style scrolling video app. (TikSlop?)THEN we're considering the case of “AI actress” Tilly Norwood, and whether her big debut is a legit shift in the world of entertainment or just a marketing gimmick-slash-sales pitch.PLUS Jason's thoughts on the Wealthfront IPO, how Spotify shifted the entire music economy, Jason's pitch for making bets with stock purchases, why Americans need more financial literacy, AND another check-in with the sharps over at Polymarket.Timestamps:(0:00) What does the government shutdown mean for startups? Not much?(04:21) Jason's an investor in Wealthfront… hear his thoughts on their potential IPO(08:14) Why Jason thinks the death of Boomers will boost crypto(10:21) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(17:26) Why is everyone so excited for Sora… but not Meta's app?(19:49) CLA - Get started with CLA's CPAs, consultants, and wealth advisors now at https://claconnect.com/tech(28:38) Is Tilly Norwood just a gimmick or Hollywood's next hot ingenue?(29:15) Perspective.ai - Real insights, straight from your customers, and your first two months are on us. Just go to getperspective.ai/twist.(35:58) POLYMARKET: When is OpenAI's browser coming out?!(40:17) How Spotify changed the entire economy of music… and when a Founder/CEO should hang it up.(47:24) Why Jason thinks Americans need better financial education and literacy(49:39) Audience Q: What's the best place to buy secondaries?(52:49) Why you should bet small while you're learningSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!CLA - Get started with CLA's CPAs, consultants, and wealth advisors now at https://claconnect.com/techPerspective.ai - Real insights, straight from your customers, and your first two months are on us. Just go to getperspective.ai/twist.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

How do you find joy in your life? For entrepreneur, venture capitalist, and author Reid Hoffman, it's through the act of genuine, honest, and intimate conversations with friends. Once a self-described misfit, in college, Reid finds his place. He connects with people who share not necessarily his interests but his curiosity, and his dedication to asking big questions. It is in asking the big questions, in discussing the answers, that Reid learns and grows – and begins to discover the meaning of his life.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Figma burst into the public eye in 2022 after Adobe was blocked from buying the design startup for $20 billion. This chapter set the stage for an even bigger milestone at Figma: a splashy IPO this summer at nearly double that valuation. Dylan Field, Figma's co-founder and CEO, joins Rapid Response to share what distinguishes Figma from competitors, and why design is increasingly at the center of every industry in today's software-driven economy. Field also reflects on the pressures and opportunities of leading as a next-generation, tech-native CEO, and offers practical advice on upskilling in an AI-powered world.Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today's show:How do you get investors excited about jets when they're hyper-focused on new AI tools?In a fresh TWiST 500 interview, Alex sits down with Blake Scholl of Boom Supersonic to talk about the Overture, the world's fastest plane that recently broke the sound barrier over the Mojave Desert. (That's a first for a private company, rather than a military or government.)Hear about the secrets to avoiding a noisy and disruptive sonic boom, using satellites to set the most efficient routes, designing the Overture's complex engine, dispelling the common myth that hardware startups are money pits and much much more.PLUS we've got two brand new companies entering our Gamma Pitch Deck Competition. Time to see how they stack up to our first impressive entrant, Where2Wheel.Timestamps:(02:22) Introducing Blake Scholl from Boom Supersonic(04:03) How Boom is improving on the classic Concorde experience(08:29) How hyper-fast Overture flights could change passenger behavior(10:02) Gusto. Check out the online payroll and benefits experts with software built specifically for small business and startups. Try Gusto today and get three months FREE at Gusto.com/twist.(11:10) The long road to breaking the speed barrier(14:34) How satellites could help guide Boom's planes(16:37) The next milestones to check off Blake's list(19:13) Breaking up the jet engine duopoly(20:57) Nexos.ai Stop Shadow AI in its tracks with the unified platform for secure AI adoption and productivity. Try it with a free 14-day trial at nexos.ai/twist.(24:28) How 3D printing speeds up the R&D process(30:26) DevStats translates complex engineering metrics into a shared language everyone at your company can understand. Get 20% off by going to https://www.DevStats.com/twist(34:10) Gamma Pitch Deck Competition: Confy vs. The Drive AISubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Gusto. Check out the online payroll and benefits experts with software built specifically for small business and startups. Try Gusto today and get three months FREE at Gusto.com/twist.Nexos.ai Stop Shadow AI in its tracks with the unified platform for secure AI adoption and productivity. Try it with a free 14-day trial at nexos.ai/twist.DevStats translates complex engineering metrics into a shared language everyone at your company can understand. Get 20% off by going to https://www.DevStats.com/twistGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

Travis and producer Eric break down one of the most polarizing topics in entrepreneurship: is it better to bootstrap a business, or raise outside capital? Drawing on personal experience and lessons from startup culture, Travis reveals the biggest mistakes founders make when chasing VC funding, why Silicon Valley's obsession with investment misleads so many, and the first principles everyone should use to decide how to launch any new company. On this episode we talk about:   The dangers and downsides of raising funding too early—even if the “checklist” seems to fit your business   Why bootstrapping builds discipline, pressure, and actual proof of concept (and how to get creative when money is tight)   When venture capital makes sense—and all the hidden costs of taking outside money, from loss of control to preferential contracts   How AI is changing the software startup equation, and shrinking the need to raise massive amounts of funding   Lessons learned from infamous failures (like Quibi) and the right ways to audit your business before chasing investment Top 3 Takeaways 1.  Bootstrapping is almost always the better first move; it boosts discipline, real market feedback, and keeps control in the founder's hands.2.  Raising outside capital adds pressure, complex contracts, and doesn't guarantee success; cash alone never fixes a business that lacks product-market fit.3.  Use trusted frameworks (like Reid Hoffman's Blitzscaling checklist), consult experienced founders, and remember: don't give away control unless it's truly required for growth. Notable Quotes   “If at all possible, bootstrap first—even just to prove your concept. Outside money makes everything more complicated.”   “Cash doesn't solve all your problems. There are usually bigger issues at play—product, marketing, market fit—that have nothing to do with funding volume.”   “The moment you take other people's money, it gets harder, not easier; discipline and focus will always win.” Connect with Travis Chappell:   LinkedIn: Travis Chappell on LinkedIn   Twitter/X: @travischappell   Instagram: @travischappell   Website: travischappell.com ✖️✖️✖️✖️

Today's show:Friend's new AI pendant just wants to be your new pal. So why do New Yorkers hate them?On a brand-new TWiST, Jason and Alex consider the Friend AI pendant, which listens to everything you say all day and then sends you snarky texts about it.WIRED says it's unhelpful and will make your friends hate you. New Yorkers are so sick of their aggressive subway ads, they're tagging them with graffiti. But what do Jason and Alex think of the wearable companion?PLUS the value of bringing your last team with you to your new project… why partnerships often lead to purchases… Producer Claude got an upgrade… two fresh TWiST 500 companies… the rise and fall and further fall of Tai Lopez… AND Jason explains the rules of private jets.Timestamps:(0:00) Jason congratulations the Eagles while wondering what's going on with Philly fans(03:23) New Yorkers are not in love with these Friend AI pendants and their subway ads(10:08) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(11:28) Show Continues…(13:49) Are people actually using AI agents? Is it still too early?(17:01) Startup Lesson: The value of bringing your last team with you(19:27) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(20:43) Anthropic released the new Claude… can they catch back up with Grok?(27:13) Why Circle's community app is blowing up all of the sudden(29:23) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit https://www.aws.amazon.com/startups/credits(30:48) How startups SHOULD measure growth and profitability. And why you need to show your work.(36:42) Why human writers are about to be MORE valuable in the age of AI Slop.(42:20) TWO new startups are joining the TWiST 500… Jason's thoughts on Phia and Huxe(46:23) Influencer and bookshelf haver Tai Lopez is under investigation by the SEC! A look back at a viral superstar…(54:11) Jason explains the rules of flying in private jetsSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWISTLemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twistAWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit https://www.aws.amazon.com/startups/creditsGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

Reid Hoffman is the co-founder of LinkendIn, Manas AI, and Inflection AI. As an investor at Greylock, he is one of the leading figures in the tech industry, working at the forefront of AI development. In this episode, Reid and Robinson talk all about the future of AI. They begin by covering the worst case scenario—doomsday—and why Reid is optimistic about our chances. From there, they turn to how AI could help us cure cancer, replace therapists, enable us to be more powerful agents, and make our lives better. Reid's most recent book is Superagency: What Could Possibly Go Right with Our AI Future (2025).Reid's Website: https://www.reidhoffman.orgSuperagency: https://a.co/d/hdSZeCYOUTLINE00:00:00 Introduction00:01:09 Why Won't AI Destroy Humanity?00:06:39 Will AI Be Good or Bad for Employment?00:08:20 On Optimism00:10:10 It Isn't Inevitable that AI Will Wipe Out Human Life00:19:03 How to Align AI with Human Interests00:24:40 Reid's Interest in Friendship00:32:13 Why AI Can't be Our Friends00:36:33 Could AI Replace Therapists?00:45:18 Using AI to Cure Cancer00:52:04 Will AI Extinguish Humanity with a Virus?01:00:02 How Will AI Make Us More Powerful Agents?01:07:06 Will Academia Be Revolutionized by AI?01:15:10 Are You an AI Native?01:17:36 How to Invest in AIRobinson's Website: http://robinsonerhardt.comRobinson Erhardt researches symbolic logic and the foundations of mathematics at Stanford University, where he is also a JD candidate in the Law School.

In this episode of Pioneers of AI, Jeffrey Katzenberg and ChenLi Wang of the venture capital firm WndrCo share why storytelling is essential for building transformative companies and how AI shapes their work. Learn more about Pioneers of AI: http://pioneersof.ai/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today's show:Factory, a Sequoia-backed producer of AI agents for programming, raised $50 million at a $300 million valuation. So Jason and Alex are wondering… how much capital is TOO MUCH?We're going deep on a question that often perplexes founders: How would weigh a HUGE potential market against STIFF pre-existing competition.PLUS that Neon app that records your calls deleted itself, why AI ISN'T taking away all the radiology jobs yet, how inherent biases impact everyone's view of the economy, ChatGPT may be getting ads very soon, and MUCH MUCH MORE.Timestamps:(0:00) The Neon app: why would anyone let an app record all of their phone calls?(04:43) Another -slop term… What is THINKSLOP?!(09:46) .TECH: Say it without saying it. Head to get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.(11:25) Why is TikTok US only worth $14 billion?!(17:10) Wait, why ISN'T AI taking jobs away from radiologists?(20:06) Public - Take your investing to the next level with Public. Build a multi-asset portfolio and earn 4.1% APY on your cash—with no fees or minimums. Start now at public.com/twist(28:38) How can xAI afford to sell AI to the US gov't for 42 cents?(29:37) Alphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at https://www.alpha-sense.com/twist(33:44) How inherent biases impact everyone's view of the economy.(46:29) Why is everyone dunking on Meta's new SlopTok app?(53:37) It certainly seems like ChatGPT is going to get ads soon…(03:49) The first entry in our Gamma Pitch Deck Competition is II off-roading marketplace Where2WheelSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:.TECH: Say it without saying it. Head to get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.Public - Take your investing to the next level with Public. Build a multi-asset portfolio and earn 4.1% APY on your cash—with no fees or minimums. Start now at public.com/twistAlphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at https://www.alpha-sense.com/twistGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

Mark talks about Trump's appearance at the UN; the Obama Presidential library in Chicago; Reid Hoffman's funding of protests; Staten Island priciest home sold; Johnny Carson former house is for sale for $110 million; the NYC Mayoral race; Netanyahu's powerful speech at the UN; Trump vs. Curtis Sliwa and Jack Schlossberg running for Jerry Nadler's seat in Congress.

Mark talks about Trump's appearance at the UN; the Obama Presidential library in Chicago; Reid Hoffman's funding of protests; Staten Island priciest home sold; Johnny Carson former house is for sale for $110 million; the NYC Mayoral race; Netanyahu's powerful speech at the UN; Trump vs. Curtis Sliwa and Jack Schlossberg running for Jerry Nadler's seat in Congress. See omnystudio.com/listener for privacy information.

What happens when your team doesn't trust each other? How can you repair damaged trust at work? How has technology changed the way we decide who to trust? Author and trust researcher Rachel Botsman joins host Jeff Berman to tackle these questions and more. Her latest book is How to Trust and Be Trusted: https://www.rachelbotsman.com/work/how-to-trust-and-be-trustedSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today's show:What is “workslop”? And is it already slowing you down at the office?On a new This Week in Startups, we've got full co-host quorum with JCal, Alex, AND Lon tackling a meaty docket of news at the cross-section of tech, startups, and pop culture.For starters: A new Harvard/Stanford study suggests that AI isn't massively improving workplace efficiency because SOME workers aren't using it properly. Are low-quality, lazily-assembled AI outputs costing US enterprises millions in lost productivity? It's certainly possible based on these results.PLUS, why YouTube invited back all those banned creators… a deep-dive into CA's new social media law that's dividing tech and civil rights advocacy groups… what we can learn from Stripe's mega-share buyback… a look at what Polymarket's sharps think will happen with the US TikTok deal… and much more.Timestamps:(0:00) Intro. What will South Park have to say about prediction markets?(06:06) Alibaba's new AI model will turn you into any celebrity… can you still believe what you see?(09:49) Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twist(11:03) Show Continues…(19:42) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit https://www.aws.amazon.com/startups/credits(21:02) Is CA's new proposed law a boon for civil rights, or a weapon against free speech?(29:47) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(32:21) Why YouTube invited banned creators back(41:24) What is Workslop? And is it costing companies MILLIONS?(48:42) PolyMarket asks… when will the US TikTok deal go down?(52:27) Would Jason invest in Tether?(01:01:29) Why Stripe is buying back so many shares… and what the future may hold.(01:12:16) Another Reddit Rapid Response: should startups do pilot programs?Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Vanta - Get $1000 off your SOC 2 at https://www.vanta.com/twistAWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit https://www.aws.amazon.com/startups/creditsNorthwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

What's the role of semiconductors—and the companies that make them—in powering human progress? What does it look like to innovate thoughtfully in a landscape where the demand for power may be higher than the supply? With AI evolving faster and faster, how can we keep up?  Advanced Micro Devices (AMD) CEO Lisa Su joins the show to talk about hardware, global manufacturing, and risk-taking. She shares what she has learned leading AMD from near-bankruptcy a decade ago to its current standing as one of the world's leading chipmakers. Lisa also weighs in on geopolitics, the AI arms race, startups, what makes her want to hire someone, and AI's enormous potential to advance healthcare for humankind.  For more info on the podcast and transcripts of all the episodes, visit https://www.possible.fm/podcast/  Topics: 2:46 - Hellos and intros 2:54 - The origins of Lisa's interest in hardware 4:19 - Deciding to bet on chips 6:06 - MIT and early engineering days 6:28 - Google Gemini defines "bunny suits" 8:25 - Differences between AMD and NVIDIA 10:25 - AI's potential to improve healthcare 16:27 - Driving AMDs comeback 19:40 - Making patience and long-term vision a company-wide virtue 22:06 - Vision for the next 10 years 24:59 - Midroll 25:16 - The impact of geopolitics on AMD 28:38 - Environmental implications of chip production   30:41 - Major hardware innovations in the start-up space 32:14 - AI driving coding acceleration 33:47 - How AMD encourages employees to leverage AI 35:22 - Identifying and empowering talent   39:08 - Rapid-fire questions Select mentions:  Liquid.ai The Worlds I See by Dr. Fei-Fei Li  Possible is an award-winning podcast that sketches out the brightest version of the future—and what it will take to get there. Most of all, it asks: what if, in the future, everything breaks humanity's way? Tune in for grounded and speculative takes on how technology—and, in particular, AI—is inspiring change and transforming the future. Hosted by Reid Hoffman and Aria Finger, each episode features an interview with an ambitious builder or deep thinker on a topic, from art to geopolitics and from healthcare to education. These conversations also showcase another kind of guest: AI. Each episode seeks to enhance and advance our discussion about what humanity could possibly get right if we leverage technology—and our collective effort—effectively.

For an organization built around responding to crises around the globe, Mercy Corps now finds itself at the center of its own trauma. Following the Trump administration's aid cuts, two-thirds of Mercy Corps' US-funded programs have been rescinded. CEO Tjada D'Oyen McKenna joins Rapid Response to share how she's leading her team amid immense pressure—scrambling to find new ways to help those in need, even as she resorts to layoffs to keep the business afloat. McKenna reveals what she's hearing from her team of aid workers on the ground in Gaza, and why she isn't running away from burnout but embracing it. Like many business leaders experiencing political or economic volatility right now, McKenna is faced with a complex conundrum: fight, flight, or freeze.Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today's show:New proposal on H-1B visas… and it's pretty similar to Jason's pitch from last month!On a new TWiST, Jason and Lon wonder if the White House is watching the pod and borrowing some of our best ideas! Specifically, the new $100K H-1B visa proposal sounds a lot like Jason's suggestion from August… with a few significant tweaks.PLUS we're looking at the latest news about the US TikTok entity, why Jason's not concerned about the new algorithm, the explosion of major data centers in Scandinavia, the European Commission's scaling back of anti-cookie regulations, AND the first big marketing push from virtual assistant startup Howie! That's a packed show!Timestamps:(0:00) Alex is out today so Jason and Lon introduce the show.(04:11) Did they borrow their new H-1B visa proposal from JCal?(10:10) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(11:28) Show Continues…(19:21) Public - Take your investing to the next level with Public. Build a multi-asset portfolio and earn 4.1% APY on your cash—with no fees or minimums. Start now at public.com/twist(20:28) Show Continues…(26:42) Answering YOUR pressing H-1B questions.(30:13) Stripe Startups - Stripe Startups offers early-stage, venture-backed startups access to Stripe fee credits and more. Apply today on stripe.com/startups.(31:30) Show Continues…(32:51) The Murdochs are likely joining the TikTok deal…(34:38) Why Jason's not concerned about TikTok being in the hands of mostly Trump allies(39:29) A look inside the Nordic data center boom and why it's happening(01:03:32) Checking out Howie's first ad… how much did it cost to make?Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWISTPublic - Take your investing to the next level with Public. Build a multi-asset portfolio and earn 4.1% APY on your cash—with no fees or minimums. Start now at public.com/twistStripe Startups - Stripe Startups offers early-stage, venture-backed startups access to Stripe fee credits and more. Apply today on stripe.com/startups.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

This week we talk about corruption, influencers, and pro-monarchy protests.We also discuss Nepalese modern history, Gen Z, and kings.Recommended Book: Superagency by Reid Hoffman and Greg BeatoTranscriptThe Federal Democratic Republic of Nepal, usually referred to as just Nepal, is a country located in the Himalayas that's bordered to the northeast by China, and is otherwise surrounded by India, including in the east, where there's a narrow sliver of India separating Nepal from Bhutan and Bangladesh.So Nepal is mostly mountainous, it's landlocked, and it's right in between two burgeoning regional powers who are also increasingly, in many ways, global powers. Its capital is Kathmandu, and there are a little over 31 million people in the country, as of 2024—more than 80% of them Hindu, and the country's landmass spans about 57,000 square miles or 147.5 square kilometers, which is little smaller than the US state of Illinois, and almost exactly the same size as Bangladesh.Modern Nepal came about beginning in the mid-20th century, when the then-ruling Rana autocracy was overthrown in the wake of neighboring India's independence movement, and a parliamentary democracy replaced it. But there was still a king, and he didn't like sharing power with the rest of the government, so he did away with the democracy component of the government in 1960, making himself the absolute monarch and banning all political activities, which also necessitated jailing politicians.The country was modernized during this period, in the sense of building out infrastructure and such, but it was pulled backwards in many ways, as there wasn't much in the way of individual liberties for civilians, and everything was heavily censored by the king and his people. In 1990, a multiparty movement called the People's Movement forced the king, this one ascended to the throne in 1972, to adopt a constitution and allow a multiparty democracy in Nepal.One of the parties that decided to enter the local political fray, the Maoist Party, started violently trying to shift the country in another direction, replacing its parliamentary system with a people's republic, similar to what was happening in China and the Soviet Union. This sparked a civil war that led to a whole lot of deaths, including those of the King and Crown Prince. The now-dead king's brother stepped in, gave himself a bunch of new powers, and then tried to stomp the Maoist Party into submission.But there was a peaceful democratic revolution in the country in 2006, at which point the Maoists put down their arms and became a normal, nonviolent political party. Nepal then became a secular state, after being a Hindu kingdom for most of their modern history, and a few years later became a federal republic. It took a little while, and there was quite a bit of tumult in the meantime, but eventually, in 2015, the Nepalese government got a new constitution that divided the country into seven provinces and made Nepal a federal democratic republic.What I'd like to talk about today is what has happened in the past decade in Nepal, and how those happenings led to a recent, seemingly pretty successful, series of protests.—In early 2025, from March through early June, a series of protests were held across Nepal by pro-monarchy citizens and the local pro-monarchy party, initially in response to the former King's visit, but later to basically just show discontentment with the current government.These protests were at least partly politically motivated, in the sense of being planned and fanned into larger conflagrations by that pro-monarchy party—not truly grassroots sort of thing—but they grew and grew, partly on the strength of opposition to the police response to earlier protests.That same distaste carried through the year, into September of 2025, when the Nepalese government announced a ban on 26 social media platforms, including Facebook, Instagram, Reddit, and Youtube, because the companies behind these platforms ostensibly failed to register under the Ministry of Communication and Information Technology's new rules that required, among other things, they have local liaisons that the government could meet with in person, and complain to if a given network failed to remove something they didn't like quickly enough.The general sense about that ban is that while this failure to properly register was used as justification for shutting down these networks, which are incredibly popular in the country, the real reason the government wanted to shut them down at that moment was that a trend had emerged online in which the rich and powerful in the country, and especially their children, many of whom have become online influencers, were being criticized for their immense opulence and for bragging about their families' vast wealth, while everyone else was comparably suffering.This became known as the Nepobaby or Nepo Kid trend, hashtag Nepobaby, which was a tag borrowed from Indonesia, and the general idea is that taxpayer money is being used to enriched a few powerful families at the expense of everyone else, and the kids of those powerful families were bragging about it in public spaces, not even bothering to hide their families' misdeeds and corruption.This, perhaps understandably, led to a lot more discontent, and all that simmering anger led to online outcries, the government tried to stifle these outcries by shutting down these networks in the country, but that shut down, as is often the case in such situations, led to in-person protests, which started out as peaceful demonstrations in Kathmandu and surrounding areas, but which eventually became violent when the police started firing tear gas and rubber bullets at the crowds, causing 19 deaths and hundreds of injuries.The ban was implemented on September 4 and then lifted, after the initial protests, on September 8, but the government's response seems to have made this a much bigger thing than it initially was, and maybe bigger than it would have become, sans that response.It's worth mentioning here, too, that a lot of young people in Nepal rely on social media and messaging apps like Signal, which was also banned, for their livelihood. Both for social media related work, and for various sorts of remittances. And that, combined with an existing 20% youth unemployment rate, meant that young people were very riled up and unhappy with the state of things, already, and this ban just poured fuel on that flame.On that same note, the median age in Nepal is 25, it's a relatively young country. So there are a lot of Gen Zers in Nepal, they're the generation that uses social media the most, and because they rely so heavily on these networks to stay in touch with each other and the world, the ban triggered a mass outpouring of anger, and that led to huge protests in a very short time.These protests grew in scope, eventually leading to the burning of government buildings, the military was called in to help bring order, and ultimately the Home Minister, and then the Prime Minister, on September 8 and 9, respectively, resigned. A lot of the burning of government buildings happened after those resignations; protestors eventually burned the homes of government ministers, and the residences of the prime minister and president, as well.The protestors didn't have any formal leadership, though there were attempts during the protests by local pro-monarchy parties and representatives to position the protests as pro-King—something most protestors have said is not the case, but you can see why that might have worked for them, considering those pro-monarchy protests earlier this year.That said, by September 10, the military was patrolling most major cities, and on the 11th, the president, head general, and Gen Z representatives for the protestors met to select an interim leader. They ended up using Discord, a chat app often used by gamers, to select a former Supreme Court Justice, Sushila Karki, as the interim prime minister, and the first woman to be prime minister in Nepalese history. Parliament was then dissolved, and March 5 was set as the date for the next election. Karki has said she will remain in office for no more than six months.As of September 13, all curfews had been lifted across Nepal, the prime minister was visiting injured protestors in hospitals, and relative calm had returned—though at least 72 people are said to have been killed during the protests, and more than 2,000 were injured.There are currently calls for unity across the political spectrum in Nepal, with everyone seeming to see the writing on the wall, that the youths have shown their strength, and there's a fresh need to toe the new line that's been established, lest the existing parties and power structures be completely toppled.There's a chance that this newfound unity against government overreach and censorship will hold, though it's important to note that the folks who were allegedly siphoning resources for their families were all able to escape the country, most without harm, due to assistance from police and the military, and that means they could influence things, from exile or after returning to Nepal, in the lead-up to that March election.It's also possible that the major parties will do more to favor the huge Gen Z population in Nepal from this point forward, which could result in less unemployment and freer speech—though if the King and the pro-monarchy party is able to continue insinuating themselves into these sorts of conversations, positioning themselves as an alternative to the nepotism and corruption many people in the area have reasonably come to associated with this type of democracy, there could be a resurgent effort to bring the monarchy back by those who have already seen some success in this regard, quite recently.Show Noteshttps://restofworld.org/2025/nepal-gen-z-protest/https://apnews.com/article/nepal-ban-social-media-platform-3b42bbbd07bc9b97acb4df09d42029d5https://apnews.com/article/nepal-new-prime-minister-protests-karki-0f552615029eb12574c9587d8d76ec46https://www.bbc.com/news/articles/crkj0lzlr3rohttps://kathmandupost.com/visual-stories/2025/09/08/gen-z-protest-in-kathmandu-against-corruption-and-social-media-banhttps://en.wikipedia.org/wiki/2025_Nepalese_Gen_Z_protestshttps://en.wikipedia.org/wiki/2025_Nepalese_pro-monarchy_protestshttps://en.wikipedia.org/wiki/Nepal This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit letsknowthings.substack.com/subscribe

Today's show:On an action-packed TWiST, Alex and Jason check out Meta's latest wearables, which promise to fix the “constantly staring down at your phone” problem and prevent you from blocking that little light letting others know you're filming them. Think the upgrade is worth $799 of your hard-earned money?PLUS, Lovable CEO Anton Osika stops by to answer YOUR questions, talk about how people are using the iconic vibecoding app, balancing accessibility and user engagement with the need to actually bring in revenue, and why Stockholm has become arguably Europe's leading tech hub.AND Beehiiv joins with Discord, Google bakes Gemini into Chrome, and MORE of the week's biggest tech news. Check out all this and more in a brand-new “This Week in Startups”!Timestamps:(0:00) Why Jason thinks Meta's new $799 Smart Ray Bans, which covertly record people in 3K, are creepy!(04:14) Why, in the technology business, not quitting is how you succeed.(09:47) .TECH: Say it without saying it. Head to get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.(10:54) Show Continues…(17:02) Anton Osika from Lovable calls in from Stockholm: Why he thinks it's Europe's biggest tech hub.(20:37) Sentry - New users get 3 months free of the Business plan (covers 150k errors). Go to http://sentry.io/twist and use code TWIST(21:44) A look at Lovable's new security features, to make founders feel more confident in their vibe coding(27:31) How Lovable is balancing engagement with the need to make money(29:55) Alphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at https://www.alpha-sense.com/twist(31:03) Show Continues…(42:29) Anton's tactical advice for founders who want to build a community around their product.(49:14) A viewer asks: Is vibe coding CHEATING?(59:01) Google is baking Gemini into Chrome… but how will it work? And what about privacy?(01:05:05) Beehiiv links up with Discord. Why Alex has a few concerns!(01:11:01) Responding to some of YOUR comments. (Leave us reviews and comments on Apple and Spotify!)Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:.TECH: Say it without saying it. Head to get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.Sentry - New users get 3 months free of the Business plan (covers 150k errors). Go to http://sentry.io/twist and use code TWISTAlphasense - Get deeper insights into your business with the power of AI search and market intelligence. Start with a free trial at https://www.alpha-sense.com/twistGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

A great mentor can supercharge your career. That's why author and entrepreneur Janice Omadeke wanted to make it easier for people to connect with the best possible mentors. She joins host Jeff Berman to reveal the insights from her book, Mentorship Unlocked, and lessons from her own journey as the founder of a tech platform for corporate mentorship.Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today's show:Hear why Eric Jackson thinks Opendoor is the new Carvana, and how he's planning to bring Drake on board as an investor (plus Jason's Bestie Chamath).On a brand-new TWiST, Jason and Alex are chatting with Jackson of EMJ Capital about his hunt for elusive 100 baggers (stocks that return 100-to-1).PLUS we're chatting with Weave Robotics' Kaan Doğrusöz about designing practical domestic robots RIGHT NOW, rather than prototypes for 2030. Hear about how they got Isaac to fold laundry like a pro.All that and… how Jason would turn around TechCrunch, why board members should always have skin in the game, that Waymo motorcycle accident, AND Uber and Tesla's first team-up to haul freight!Timestamps:(0:00) Jason is worried about the next generation facing the end of apprenticeship; here's his advice for young workers(10:24) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(11:30) Kaan Doğrusöz of Weave Robotics joins to talk about getting his laundry-folding robot, Isaac, into customer's homes(18:01) Isaac doesn't have hands; here's how Weave makes it work with grippers(20:44) Stripe Startups - Stripe Startups offers early-stage, venture-backed startups access to Stripe fee credits and more. Apply today on stripe.com/startups.(21:48) Show Continues…(24:51) Checking out some of Weave's competitors… how did they settle on Isaac's design?(30:01) Miro - Help your teams get great done with Miro. Check out miro.com to find out how!(31:10) What's going on with TikTok?(36:15) Jason's pitch is “BOYA”: Bring Your Own Algorithm(38:54) Eric Jackson of EMJ Capital stops by to talk up $OPEN and why he wants Drake to invest(40:14) Eric's early YouTube career as an activist Yahoo! Investor(44:42) Lessons Eric learned from Carvana and how that informed his $OPEN bet(01:00:30) Why bringing Keith Rabois back was Eric's ultimate dream for Opendoor(01:03:02) Why board members should always have “skin in the game” and why $OPEN wants Chamath back(01:07:26) Tesla and Uber are finally working together… They said it was impossible!(01:09:31) A look at YouTube's new AI podcasting featuresSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!Stripe Startups - Stripe Startups offers early-stage, venture-backed startups access to Stripe fee credits and more. Apply today on stripe.com/startups.Miro - Help your teams get great done with Miro. Check out miro.com to find out how!Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

Download this week's deck: http://diamandis.com/wtf  Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends   Grab dinner with MOONSHOT listeners: https://moonshots.dnnr.io/  Salim Ismail is the founder of OpenExO Dave Blundin is the founder & GP of Link Ventures Dr. Alexander Wissner-Gross is a computer scientist and founder of Reified, focused on AI and complex systems. Reid Hoffman is an entrepreneur, investor, and LinkedIn co-founder focused on AI and human progress. – My companies: Reverse the age of my skin using the same cream at https://qr.diamandis.com/oneskinpod   Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding   – Connect with Peter: X Instagram Connect with Dave: X LinkedIn Connect with Salim: X Join Salim's Workshop to build your ExO: https://openexo.com/10x-shift?video=PeterD062625 Connect with Alex Website LinkedIn X Email Connect with Reid X LinkedIn Listen to MOONSHOTS: Apple YouTube – *Recorded on September 11th, 2025 *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice. Learn more about your ad choices. Visit megaphone.fm/adchoices

Pablos Holman is a hacker and inventor and the author of Deep Future: Creating Technology that Matters, the indispensable guide to deep tech. Previously, Pablos worked on spaceships at Blue Origin and helped build The Intellectual Ventures Lab to invent a wide variety of breakthroughs. Pablos also hosts the Deep Future Podcast and is managing partner at Deep Future.This episode is brought to you by:Cresset prestigious family office for CEOs, founders, and entrepreneurs: https://cressetcapital.com/timMaui Nui Venison​, delicious, nutrient-dense, and responsible red meat: https://mauinuivenison.com/lp/timAG1 all-in-one nutritional supplement: https://drinkag1.com/timTimestamps:00:00 Intro02:12 The hacker mindset33:05 Nuclear52:35 Autonomous ships58:48 Pragmatic optimism01:00:29 Risk tolerance01:04:50 Blue Origin01:11:59 Zero Effect philosophy01:34:43 China01:43:07 Taiwan01:45:04 AI01:50:42 Salsa02:08:44 Deep tech investing*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissPast guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, Margaret Atwood, Mark Zuckerberg, Peter Thiel, Dr. Gabor Maté, Anne Lamott, Sarah Silverman, Dr. Andrew Huberman, and many more.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

As the fashion world navigates an unprecedented wave of turnover from Chanel to Dior, WSJ. Magazine's Editor in Chief, Sarah Ball joins Rapid Response to explore the most closely watched New York Fashion Week in years — what she calls "a September to remember." Ball also shares insights about how Vogue is poised to take shape post-Anna Wintour, the shockwaves from Georgio Armani's recent passing, AI's impact on fashion creatives, and how the role of influencers and social media is noticeably reshaping where the industry is headed.Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

The future is something we create, not just something that happens. To guide progress toward real good, we need bold, optimistic visions of what society can become.Reid Hoffman makes the case for better science fiction - stories that don't just entertain, but illuminate the futures we can strive for. As a serial entrepreneur and cofounder of LinkedIn, Reid brings a unique perspective on how storytelling shapes technology, society, and innovation. He argues that imagining optimistic futures is essential if we want to create them.In this episode, we also explore how technology like AI is changing the way our brains work and how our faculties will evolve, why humanity has shifted from focusing on external threats to internal ones, and how optimism isn't blind faith—it's a clear-eyed strategy for shaping a better world.This is... A Bit of Optimism. Check out Reid's new book here: https://www.superagency.ai/SUPERAGENCY: What Could Possibly Go Right with Our AI Future

Today's show:On a special edition of TWiST, Alex presents a trio of TWiST 500 interviews.First up, Medium CEO Tony Stubblebine on the company's new Really Simple Licensing (or RSL) initiative, and how it's helping to compensate writers for their content.THEN, Human Native CEO Dr. James Smith joins for an even deeper dive on AI licensing, why a writer's content isn't just DATA to them, and why the company is pivoting away from its old marketplace model.FINALLY, Jason Marks of TELO Trucks stops by to show off his EV mini-truck, walk us through why people need a powerful but tiny truck, and explain why they're building trucks right here in the US of A.Timestamps:(0:00) Intro: It's a trio of TWiST 500 interviews today!(02:57) Alex chats with Medium CEO Tony Stubblebine(04:54) Why Medium's more worried about HIDING from AI than anything else(10:24) Nexos.ai. Stop Shadow AI in its tracks with the unified platform for secure AI adoption and productivity. Try it with a free 14-day trial at nexos.ai/twist.(11:27) Show Continues…(15:02) What is RSL and why aren't AI companies offering publishers a good value?(19:58) Gusto. Check out the online payroll and benefits experts with software built specifically for small business and startups. Try Gusto today and get three months FREE at Gusto.com/twist.(20:59) Show Continues…(22:03) How Medium calculates its revenue split with writers(26:57) Alex welcomes Human Native CEO/founder Dr. James Smith.(27:34) Writers see their content as their life's work, but tech co's just see DATA(30:01) DevStats translates complex engineering metrics into a shared language everyone at your company can understand. Get 20% off by going to DevStats.com/twist(31:06) Show Continues…(33:01) Why H.N. is pivoting away from licensing and the marketplace model(47:23) TELO Trucks CEO Jason Marks joins the show(48:25) What is a “mini-truck” and why they're TELO's focus(52:28) Why TELO is building their EV trucks right here in the US(54:42) Why towing capacity still matters, even on a mini-truckSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Nexos.ai. Stop Shadow AI in its tracks with the unified platform for secure AI adoption and productivity. Try it with a free 14-day trial at nexos.ai/twist.Gusto. Check out the online payroll and benefits experts with software built specifically for small business and startups. Try Gusto today and get three months FREE at Gusto.com/twist.DevStats translates complex engineering metrics into a shared language everyone at your company can understand. Get 20% off by going to DevStats.com/twistGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

Today's show:There are new LAUNCH Accelerator and Founder U cohorts this week, and Jason's running down some of his favorite new startups.PLUS Alphabet is the latest member of the $3T club, why Eric Schmidt was SO RIGHT about remote work, Robinhood is opening up private companies to more investors, Polymarket adds earnings reports, how Jason wagered on The Emmys this year, and MORE!Timestamps:(0:00) It's kickoff day for LAUNCH Accelerator 35 AND Founder University!(02:32) Let's talk about some new companies. Jason runs down the LA35 line-up and why he's excited about these awesome startups.(10:33) OpenPhone - Streamline and scale your customer communications with OpenPhone. Get 20% off your first 6 months at https://www.openphone.com/twist(11:57) Show Continues…(19:50) Squarespace - Turn your idea into a beautiful website! Go to http://www.squarespace.com/twist for a free trial. When you're ready to launch, use offer code TWIST to save 10% off your first purchase of a website or domain.(21:05) Show Continues…(27:43) Lemon.io - Hire pre-vetted remote developers and get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(28:58) Looking back at Jason's solar energy rematch vs. Energy Sec. Chris Wright.(31:23) Why Jason thinks solar power (+nuclear) is the future.(41:03) Why Alphabet is the latest member of the $3 trillion market cap club.(46:40) Jason says Eric Schmidt was right about work from home culture(48:51) How Robinhood is giving everyday investors access to private companies(51:44) Polymarket introduces prediction markets for corporate earnings.(53:58) Why Jason loves prediction markets… and how he gambled on the Emmys this year.Subscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:OpenPhone - Streamline and scale your customer communications with OpenPhone. Get 20% off your first 6 months at https://www.openphone.com/twistSquarespace - Turn your idea into a beautiful website! Go to http://www.squarespace.com/twist for a free trial. When you're ready to launch, use offer code TWIST to save 10% off your first purchase of a website or domain.Lemon.io - Hire pre-vetted remote developers and get 15% off your first 4 weeks of developer time at https://Lemon.io/twistGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

On the latest episode of Reid Hoffman's Possible podcast, he and Aria talk with comedian Stephen Colbert. They discuss how J.R.R. Tolkien helps The Late Show host make sense of AI, whether technology will ever be able to replicate the ‘micronutrients' of human interaction, and more. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today's show:On Friday's TWiST, Jason, Alex, and Lon look back at some highlights from this week's big All-In Summit in Los Angeles, including a fiery, no holds barred presentation from Palantir CEO Alex Karp, Elon Musk delving into the key challenges facing Optimus, and Tucker Carlson debating Mark Cuban on Ukraine. PLUS… why schools may start blocking social media apps, the FTC's new investigation into social chatbots, AND omnidirectional Zoox robotaxis are headed to Las Vegas.Timestamps:Welcome back to TWiST!(1:52) Jason's thoughts on the killing of Charlie Kirk(10:34) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(10:52) Show Continues …(12:15) Reacting to All-In Summit highlights (Elon Musk, Alex Karp, Tucker Carlson, Mark Cuban)(21:23) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit https://www.aws.amazon.com/startups/credits(22:18) Show Continues …(26:09) Palantir, Alex Karp, and debate dynamics(31:03) Public - Take your investing to the next level with Public. Build a multi-asset portfolio and earn 4.1% APY on your cash—with no fees or minimums. Start now at public.com/twist(32:13) Show Continues …(45:03) How the internet used AI tools to make sense of Charlie Kirk's death(56:22) Why Jason thinks it's smart to block social media during school hours(1:03:43) The FTC chatbot investigation leaves out Anthropic's Claude… here's why(1:13:27) Zoox robotaxis make their Vegas debut… Here's how they're different from Waymo(1:19:38) Are Tesla robotaxis headed for CA soon? Polymarket says… maybe(1:27:21) Closing remarks and banterSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWISTAWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit https://www.aws.amazon.com/startups/creditsPublic - Take your investing to the next level with Public. Build a multi-asset portfolio and earn 4.1% APY on your cash—with no fees or minimums. Start now at public.com/twistGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

Podcast description: Matthew Pohlson's dreams of building a company were almost cut short by a near-death experience. The CEO and co-founder of Omaze reveals how it changed his mindset, and unlocked new ways to scale his business. Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

God's Debris: The Complete Works, Amazon https://tinyurl.com/GodsDebrisCompleteWorksFind my "extra" content on Locals: https://ScottAdams.Locals.comContent:Politics, Charlie Kirk, Van Jones, Governor Pritzker, Elizabeth Warren, Matthew Dowd, Republicans Hunted, President Obama, Stephen Miller, Terry Wilson BLM, TMZ Cheer, Hypnotized democrat Celebrations, Mike Cernovich, Reid Hoffman, Risk Tolerance, democrat Leadership, Elon Musk, Matt Von Swol, President Trump, Code Pink Protesters, PM Netanyahu, Risk Management, Recency Bias, Palmer Luckey, Ryan Routh Trial, Scott Adams~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~If you would like to enjoy this same content plus bonus content from Scott Adams, including micro-lessons on lots of useful topics to build your talent stack, please see scottadams.locals.com for full access to that secret treasure.

Today's show:In this founder-focused episode of This Week in Startups, we sit down with Republic's Kendrick Nguyen to learn more about the company's efforts to make the private markets accessible to the common investor. Best known for its work in equity crowdfunding, the Valor-backed startup now offers access to secondary shares, tokenized assets, and much more. Following, TWiST spoke with Positron CEO Mitesh Agrawal to learn more about his company's inference-focused AI compute hardware. Related to fellow TWiST500 company Etched, Positron is building custom chips to take on the computing work required to deliver your AI query results faster and with less power draw than what GPUs can offer. With AI inference compute demand rising, the fellow Valor-backed startup has even more powerful systems coming to market in 2026 that have our hopes up that the AI cost curve can continue to point downward.Timestamps:0:00 - A future with more efficient and accessible intelligence0:41, the following sponsors are mentioned: AlphaSense, Vanta, and Oracle Cloud Infrastructure1:26 - Introduction to the episode and the two featured companies, Republic and Positron2:43 - The history and purpose of Republic, a financial crowdfunding platform5:39 - Discussion of the current state and growth of equity crowdfunding9:19 - Kendrick Nguyen explains Republic's role as a financial infrastructure company, not a competitor to venture capital firms11:17 - Sponsor: Oracle Cloud Infrastructure12:25 - Republic's different products, Republic Capital and Republic Venture, are explained14:00 - The challenges and progress of secondary trading for non-accredited investors20:14 - Sponsor: Vanta21:21 - The concept of a unified "e-finance" infrastructure is introduced25:45 - Positron CEO Mitesh Agarwal discusses the future of AI chips and the limitations of current GPUs for inference workloads31:12 - Sponsor: AlphaSense32:22 - Discussion on the inefficiency of GPUs for inference and how Positron's Atlas system addresses it38:30 - Positron's strategy of using their Atlas system to prove their technology and generate revenue42:51 - The market shift from AI training to inference and the future of Positron's chips51:14 - The confidence in Positron's capital efficiency and their ability to compete with NVIDIA52:47 - Positron's focus on linear algebra acceleration rather than just transformersSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(09:04) Netsuite - Download the ebook CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twist(21:20) Coda - Empower your startup with Coda's Team plan for free—get 6 months at https://www.Coda.io/twist(31:43) .TECH: Say it without saying it. Head to get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

This episode is a solo Q&A session where I answer a bunch of questions. We covered a ton of ground, from personal health protocols to professional frameworks and creative projects. This episode is brought to you by:Eight Sleep Pod Cover 5 sleeping solution for dynamic cooling and heating: EightSleep.com/Tim (use code TIM to get $350 off your very own Pod 5 Ultra.)Monarch Money track, budget, plan, and do more with your money: MonarchMoney.com/Tim (50% off your first year at monarchmoney.com with code TIM)Shopify global commerce platform, providing tools to start, grow, market, and manage a retail business: https://shopify.com/tim (one-dollar-per-month trial period)Timestamps: [00:00:00] Start[00:06:00] Coyote retail distribution challenges and data gathering.[00:09:12] Elbow surgery recovery: sequencing, decongestion, Marc Pro device, peptides, BFR training.[00:16:14] California vs. Austin for builders, mechanical engineers, and tech startups.[00:19:06] Using AI for medical advice workflow (and cross-referencing with professionals).[00:23:51] Current supplement regimen and PAGG/AGG status.[00:31:54] California vs. Texas considerations for aspiring parents.[00:32:48] Saying "No" to good things for "Hell, yes" moments.[00:34:34] Philanthropy lessons learned since starting Saisei Foundation.[00:37:45] Something I've changed my mind about recently: intermittent fasting.[00:42:44] Precious items from childhood I still keep: D&D relics and marine biology books.[00:43:03] Bucket list hike: Glacier National Park.[00:43:42] How the catalytic chaos of publishing The 4-Hour Chef led to launching this podcast.[00:45:52] Bringing delight vs. sixth-gear, high-performance focus.[00:49:05] Thoughts on extended human fasting research from the Soviet era.[00:52:58] Most magical New Mexico experience: Mountain Cloud Zen Center meditation retreat.[00:53:22] Meta skills for the AI era: Hyper-adaptability and world-class learning.[00:54:01] The (real and ideal) future of CØCKPUNCH/Legends of Varlata.[00:59:47] Competitive chess training enhancement: glucose management, intermittent fasting, MCT oil.[01:06:31] Behind-the-scenes projects: Fusion, algae feed additives, meat alternatives.[01:08:32] Countries I wish I had visited earlier, and places I'd still like to see.[01:11:06] "Not yet" vs. "No" in early growth phases.[01:14:14] Post Coyote, do I have any future games in the works?[01:14:46] Over-ear vs. in-ear headphones for podcasting.[01:15:16] What's the uncrowded channel right now?[01:16:17] Recommendations for Dr. Mindy Pelz.[01:16:58] Robert Rodriguez and project juggling.[01:17:24] Fast neutron reactors and the Bugatti of ketones.[01:19:05] Extended family outings and Mahonk Mountain House.[01:20:31] NO BOOK meetup plans?[01:20:54] Parting thoughts.*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissPast guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, Margaret Atwood, Mark Zuckerberg, Peter Thiel, Dr. Gabor Maté, Anne Lamott, Sarah Silverman, Dr. Andrew Huberman, and many more.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Sunday's MTV Video Music Awards shone a light on some of the biggest storylines in the music business today – from the TikTokification of newly minted stars, to the evolving relationship between artists and brands. Music journalist and author Sowmya Krishnamurthy joins Rapid Response to break down business and cultural lessons from the show and what it reveals about the state of the industry. Krishnamurthy also explores Taylor Swift's enduring dominance, the role of AI in music, and the latest twists in the streaming war between Spotify and Apple Music.Visit the Rapid Response website here: https://www.rapidresponseshow.com/Find Sowmya's book Fashion Killa here: https://www.simonandschuster.com/books/Fashion-Killa/Sowmya-Krishnamurthy/9781982176327See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today's show:In this TWiST founder triple-shot, Alex digs into the real-world rollout of AI agents: Paid.ai's Manny Medina explains agent economics and value-based pricing, iTruckr's Camilo Ramirez shows agents booking loads and coordinating drivers, and Tenax's Elise Myrans demos computer vision + drones that score a single home's wildfire/flood risk for smarter underwriting—plus live office-hours on winning enterprise pilots without getting stuck in PoC purgatory.Timestamps:(00:00) Brainstorming hacks for sales cycles in regulated industries — castles, moats & alligators!(03:50) Meet Paid.ai: tracking costs & monetization for AI agents(04:35) Paid.ai's Manny Medina on the “year of agents” & early enterprise traction(09:04) Netsuite - Download the ebook CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twist(11:06) The tough economics of AI agents vs SaaS — margins squeezed by tokens(18:20) How Paid.ai gets granular: tracking signals & agent activity with OpenTelemetry(21:20) Coda - Empower your startup with Coda's Team plan for free—get 6 months at https://www.Coda.io/twist(29:16) Enter iTruckr: Camilo Ramirez brings AI dispatch to the freight industry(31:43) .TECH: Say it without saying it. Head to get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.(39:02) Scaling from small fleets to mid-sized trucking companies — lessons from AI Trucker(55:59) Tenax ai helps homeowners & insurers manage wildfire, flood & climate riskSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(09:04) Netsuite - Download the ebook CFO's Guide to AI and Machine Learning for free at https://www.netsuite.com/twist(21:20) Coda - Empower your startup with Coda's Team plan for free—get 6 months at https://www.Coda.io/twist(31:43) .TECH: Say it without saying it. Head to get.tech/twist or your favorite registrar to get a clean, sharp .tech domain today.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

Today's show:Jason heard Lina Khan on The Bulwark and got a little fired up.Plus Google doesn't have to invest in Chrome… or basically do much of anything… Atlassian picked up not just any browser company but THE Browser Company… Follow-up thoughts on that MIT “companies aren't using AI” study… AND Jason's “two stock markets” theory. It's a can't-miss Friday TWiST.Timestamps:(00:00) Sony responds to Kpop Demon Hunters success… but Jason's not buying it!(10:44) Sentry - New users get 3 months free of the Business plan (covers 150k errors). Go to http://sentry.io/twist and use code TWIST(11:10) Jason heard Lina Khan on The Bulwark and he has THOUGHTS(12:40) Google doesn't have to divest Chrome! So what ARE the remedies?(18:31) Atlassian's buying a browser company? Which one? THE Browser Company.(20:57) CLA - Get started with CLA's CPAs, consultants, and wealth advisors now at https://claconnect.com/tech(21:22) When early DPI is better than NO DPI.(26:58) AI that helps you GET a job?! What a twist!(29:46) Jason and Alex have questions about that MIT AI study…(30:57) Public - Take your investing to the next level with Public. Build a multi-asset portfolio and earn 4.1% APY on your cash—with no fees or minimums. Start now at public.com/twist.(32:07) More Browser News! Why Jason's bullish on Brave.(35:10) Perplexed by “Perplexity”: Jason's rules for domain names(39:54) The path is cleared for Polymarket's return to the US(47:06) Jason's “Two Stock Markets” theory(53:02) Mistral looking to raise 2 billion… euro!(56:08) Jason's political philosophy: More joy and happiness(59:18) Stripe's new stablecoin blockchain has no native token! So what's it for?(01:04:12) Jason's tips for lowering your churn rate(01:11:56) How to use Reddit to uncover pain pointsSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(10:44) Sentry - New users get 3 months free of the Business plan (covers 150k errors). Go to http://sentry.io/twist and use code TWIST(20:57) CLA - Get started with CLA's CPAs, consultants, and wealth advisors now at https://claconnect.com/tech(30:57) Public - Take your investing to the next level with Public. Build a multi-asset portfolio and earn 4.1% APY on your cash—with no fees or minimums. Start now at public.com/twist.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

As the NFL season kicks off this week, host Jeff Berman talks with a serial entrepreneur known for innovating in fantasy sports. Jeremy Levine is the founder and CEO of Underdog, a rapidly scaling unicorn. Levine reveals how a relentless focus on product helps his company break through entrenched competition.Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribeSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Today's show:Jason and Alex are joined by Nuro's Dave Ferguson to unpack the Lucid–Uber–Nuro deal aiming to launch fully driverless Gravity SUVs on Uber by 2026. They dig into why off-the-shelf sensors and Nvidia's Thor chip drive costs down, how mapping 150 cities improves safety, and why lidar still matters for night and edge cases. Plus: lessons from Cruise's collapse, how regulators think about safety multiples, and why autonomy could finally make rides cheaper than owning a car.Timestamps:(00:00) Show intro…(06:23) Uber x Lucid x Nuro: why this 2026 robotaxi deal matters(09:57) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(11:13) What the self-driving “cost stack” really looks like in 2025(14:08) Road-mapping at scale: Nuro's 150-city data collection push(15:38) Can AVs handle snow & rain? Weather rollout and Uber Black positioning(20:05) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(21:07) Show Continues…(24:24) Probabilistic vs. deterministic driving models — and the DARPA roots(30:08) Stripe Startups - Stripe Startups offers early-stage, venture-backed startups access to Stripe fee credits and more. Apply today on stripe.com/startups.(31:08) Show Continues…(35:38) Post-Cruise reality check: transparency, regulators & trustSubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(09:57) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist(20:05) Northwest Registered Agent - Form your entire business identity in just 10 clicks and 10 minutes. Get more privacy, more options, and more done—visit https://www.northwestregisteredagent.com/twist today!(30:08) Stripe Startups - Stripe Startups offers early-stage, venture-backed startups access to Stripe fee credits and more. Apply today on stripe.com/startups.Great TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

Today's show:Find out why it's important to “get curious,” and more deep founder insights on a new TWiST.Jason and Alex are back with a look at Robot vs. Human violence spilling out into the streets, Elon Musk's vision for humanoid robots, and a reconsideration of Apple's open-source AI models. Is the hardware giant not getting enough credit for its smaller-scale innovations?Plus Grok has another hit model, AND a chat with Scale Social founder Runbin Dong about the importance of knowing your worth.Timestamps:(0:00) Robot vs. Human violence in the streets! Is anti-clanker behavior inevitable?(05:13) Producer Claude's company Anthropic is growing FAST, raising BIG money(09:21) More on why Jason is convinced Tesla's Optimus robots are the future(10:35) Monarch Money - Get 50% Off Monarch Money, the all-in-one financial tool at www.monarchmoney.com/TWIST(11:50) Show Continues…(20:00) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(21:19) Show Continues…(23:31) Ask Jason: Should you get a ticket for messing with an autonomous vehicle?(27:04) Is Apple not getting enough credit for its open-source AI models?(30:30) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit aws.amazon.com/startups/credits(31:55) Show Continues…(38:08) Grok has another hit AI model… how can anyone even keep track of this?!(40:27) Runbin Dong of Scale Social stops by from ICELAND(42:54) How Runbin's job delivering homemade dumplings inspired his startup(47:05) Why founders need to know their WORTH when pricing their products(59:21) Jason's advice for companies that are creating their own categorySubscribe to the TWiST500 newsletter: https://ticker.thisweekinstartups.comCheck out the TWIST500: https://www.twist500.comSubscribe to This Week in Startups on Apple: https://rb.gy/v19fcpFollow Lon:X: https://x.com/lonsFollow Alex:X: https://x.com/alexLinkedIn: ⁠https://www.linkedin.com/in/alexwilhelmFollow Jason:X: https://twitter.com/JasonLinkedIn: https://www.linkedin.com/in/jasoncalacanisThank you to our partners:(10:35) Monarch Money - Get 50% Off Monarch Money, the all-in-one financial tool at www.monarchmoney.com/TWIST(20:00) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST(30:30) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit aws.amazon.com/startups/creditsGreat TWIST interviews: Will Guidara, Eoghan McCabe, Steve Huffman, Brian Chesky, Bob Moesta, Aaron Levie, Sophia Amoruso, Reid Hoffman, Frank Slootman, Billy McFarlandCheck out Jason's suite of newsletters: https://substack.com/@calacanisFollow TWiST:Twitter: https://twitter.com/TWiStartupsYouTube: https://www.youtube.com/thisweekinInstagram: https://www.instagram.com/thisweekinstartupsTikTok: https://www.tiktok.com/@thisweekinstartupsSubstack: https://twistartups.substack.comSubscribe to the Founder University Podcast: https://www.youtube.com/@founderuniversity1916

Grab is a rideshare service-turned superapp, not available in the US but rapidly growing in Southeast Asia. It's even outmaneuvered global players like Uber to reach a valuation north of $20 billion. Grab's co-founder and CEO Anthony Tan joins Rapid Response to share how the platform has successfully expanded into food delivery and fintech, while also investing in the future of electric vehicles and autonomous driving. For any leader looking to bolster their company culture to meet the moment, Tan shares how his team set in motion an ambitious project to study and creatively implement AI — channeling both the hunger and humility to win in a competitive and chaotic market.Visit the Rapid Response website here: https://www.rapidresponseshow.com/See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Kevin J. Tracey, MD is president and CEO of the Feinstein Institutes for Medical Research at Northwell Health, a pioneer of vagus nerve research and author of the recent book, The Great Nerve: The New Science of the Vagus Nerve and How to Harness Its Healing Reflexes. This episode is brought to you by:Eight Sleep Pod Cover 5 sleeping solution for dynamic cooling and heating: EightSleep.com/Tim (use code TIM to get $350 off your very own Pod 5 Ultra.)AG1 all-in-one nutritional supplement: https://DrinkAG1.com/Tim (1-year supply of Vitamin D plus 5 free AG1 travel packs with your first subscription purchase.)Wealthfront high-yield cash account: https://Wealthfront.com/Tim (Start earning 4.00% APY on your short-term cash until you're ready to invest. And when new clients open an account today, you can get an extra fifty-dollar bonus with a deposit of five hundred dollars or more.) Terms apply. Tim Ferriss receives cash compensation from Wealthfront Brokerage, LLC for advertising and holds a non-controlling equity interest in the corporate parent of Wealthfront Brokerage. See full disclosures here.Timestamps:00:00 Tim's intro: why he dismissed vagus-nerve hype06:34 What the vagus nerve actually is, plus common myths11:31 Breaking news: FDA approval for SetPoint's RA implant + Kelly Owens's turnaround21:11 Inflammation 101: when healing turns harmful31:37 Bioelectronic medicine: from lab insight to real devices55:26 TNF, IL-1, and IL-6: immune drivers and what VNS modulates56:06 Exercise & recovery: vagal signals, IL-6, and adaptation56:30 Cold exposure & breathwork: sympathetic spike, parasympathetic payoff59:04 Chronic inflammation today: prevalence, diagnostics, and uncertainty59:53 Autoimmunity: genes, environment, infections01:01:08 Stress hormones, personality traits, and metabolic fallout01:05:41 VNS tech landscape: implants, focused ultrasound, and what's just TENS01:11:14 Ear maps, revisited: the real science behind auricular stimulation01:27:52 Ulf Andersson: auricular TENS, famotidine, and a depression turnaround01:36:48 Depression & inflammation: where VNS helps (and where it doesn't)01:41:38 Body-brain loop: how inflammation signals ride the vagus nerve01:42:56 Why VNS can lift mood: a working theory01:43:22 Ulf's setup: electrode placement and twice-daily routine01:44:37 Acupuncture, fertility, and plausible vagal links01:47:23 Chronic pain through an inflammation lens01:48:34 Neural “engrams”: how the brain can store inflammatory memories02:02:35 Cervical TENS vs. true VNS: mechanisms and open questions02:12:15 On stage with the Dalai Lama: blue energy and two vagus nerves02:16:55 Closing thoughts: self-care vs. medical devices, and what's next*For show notes and past guests on The Tim Ferriss Show, please visit tim.blog/podcast.For deals from sponsors of The Tim Ferriss Show, please visit tim.blog/podcast-sponsorsSign up for Tim's email newsletter (5-Bullet Friday) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim's books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissYouTube: youtube.com/timferrissFacebook: facebook.com/timferriss LinkedIn: linkedin.com/in/timferrissPast guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, Margaret Atwood, Mark Zuckerberg, Peter Thiel, Dr. Gabor Maté, Anne Lamott, Sarah Silverman, Dr. Andrew Huberman, and many more.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.