Podcasts about Jenner Institute

Welcome to The Nonlinear Library, where we use Text-to-Speech software to convert the best writing from the Rationalist and EA communities into audio. This is: Suggestions for Individual Donors from Open Philanthropy Staff - 2023, published by Alexander Berger on December 20, 2023 on The Effective Altruism Forum. In past years, we sometimes published suggestions for individual donors looking for organizations to support. This post shares new suggestions from Open Philanthropy program staff who chose to provide them. Similar caveats to previous years apply: These are reasonably strong options in the relevant focus area, and shouldn't be taken as outright recommendations (i.e., it isn't necessarily the case that the person making a suggestion thinks that their suggestion is the best option available across all causes). The recommendations below fall within the cause areas Open Philanthropy has chosen to focus on. While this list does not expressly include GiveWell's top charities, we believe those organizations to be among the most cost-effective, evidence-backed giving opportunities available to donors today, and expect that some readers of this post might want to give to them. Many of these recommendations appear here because they are particularly good fits for individual donors. This shouldn't be seen as a list of our strongest grantees overall (although of course there may be overlap). Our explanations for why these are strong giving opportunities are very brief and informal, and we don't expect individuals to be persuaded by them unless they put a lot of weight on the judgment of the person making the suggestion. In addition, these recommendations are made by the individual program officers or teams cited, and do not necessarily represent my (Alexander's) personal or Open Philanthropy's institutional "all things considered" view. Global Health and Development 1Day Sooner Recommended by Chris Smith What is it? 1Day Sooner was originally created during 2020 to advocate for increased use of human challenge trials in Covid vaccines, and named on the basis that making vaccines available even one day sooner would be hugely beneficial. 1DS is now expanding its work to look at other diseases where challenge trials could be safe, such as hepatitis C, where Open Philanthropy separately has grants developing new vaccine candidates. Open Philanthropy has supported 1DS from both our GHW and GCR portfolios. Why I suggest it: Recently, 1DS have been working on accelerating the global rollout of vaccines beyond the increased use of challenge trials, such as their current campaign on R21. R21 is an effective malaria vaccine (developed in part by Open Philanthropy Program Officer Katharine Collins while she was at the Jenner Institute) recommended for use by WHO in October 2023 but with plans only to distribute fewer than 20 million doses in 2024, despite the manufacturer claiming the ability to make 100 million doses available. You can read an op-ed on this from Zacharia Kafuko, Africa Director of 1DS, in Foreign Policy. If 1DS can diversify its funding base and find more donors, they'd have the capacity to take on other projects that could accelerate vaccine development and distribution. I've been impressed with their work on both policy and advocacy, and I plan to support them myself this year. (Also, personally, I really enjoy supporting smaller organizations as a donor; I find that this helps me "feel" the difference more than if I'd donated to a large organization.) How to donate: You can donate here. Center for Global Development Recommended by Lauren Gilbert What is it? The Center for Global Development (CGD) is a Washington D.C.-based think tank. They conduct research on and promote evidence-based improvements to policies that affect the global poor. Why I suggest it: We've supported CGD for many years and have recommended it for individual donors in previous years. CGD has an impressive track record, and it continues to do impac...

Show notes and Transcript Today we delve into grass-roots activism, we have all seen the yellow boards pop up at road junctions across the country, joined with a cacophony of car horns in support.  When online censorship tries to curtail the flow of information, it's time to go back to the traditional methods. Billboards.  Francis O'Neill has become known to many of us for his high profile involvement with this new/old medium. He joins Hearts of Oak to discuss why he got involved and what the response has been from the public. The concern has moved on from forced jabs to full covid tyranny and the threat of a cashless society, with control through surveillance now the biggest threat we face to our freedom. Connect with Francis and The Yellow Boards Movement... X:                        https://x.com/FrancisxONeill?s=20                            https://x.com/YellowBoards?s=20 SUBSTACK:       https://francisoneill.substack.com/ LINKS:                https://heylink.me/yellow_boards/ Interview recorded 26.9.23 *Special thanks to Bosch Fawstin for recording our intro/outro on this podcast. Check out his art https://theboschfawstinstore.blogspot.com/ and follow him on GETTR https://gettr.com/user/BoschFawstin and Twitter https://twitter.com/TheBoschFawstin?s=20  To sign up for our weekly email, find our social media, podcasts, video, livestreaming platforms and more... https://heartsofoak.org/connect/ Support Hearts of Oak by purchasing one of our fancy T-Shirts.... https://heartsofoak.org/shop/ Please subscribe, like and share! Transcript (Hearts of Oak) Francis O'Neill. It is wonderful to have you with us.Thanks so much for giving us your time today. (Francis O'Neill) Thank you, Peter. Thanks for having me.  Great. And obviously, wanted you on, seen many of the videos, pictures, the whole thing with yellow boards, trying to get a different narrative, I guess, to what the mainstream put out. But people can find you. There is your Twitter handle @FrancisXONeill. Also, the sub stack, the links are in the description and they're also on your Twitter page. Francis, maybe before we get into what's been happening, how you've been getting a message out, the response from the public, what are the issues which have become a freedom encompasses a lot and it's become much wider than anti-Covid tyranny. Do you just want to maybe introduce yourselves, because we have probably two-thirds US audience actually now, and they may not be aware of who you are. Do that first and then we'll jump onto the yellow boards. Well, I'm actually a self-employed artist and I was teaching just life drawing and portrait painting. I was living in Oxford and making a living doing that. I was teaching from a studio, which I rented as part of a complex with other artists. And that's how I was getting by. I was doing jobs, sometimes teaching in other locations, but I'd become aware that things weren't as presented in the mainstream media due to 9-11. I had questions on the day, but I wasn't really woken up on the day. I just thought that would be resolved by investigations and so on. But as you know, with the prevalence of the internet, I mean, you start to become aware that there are alternative theories out there. I started to look into that quite deeply. And once I became aware that the official story of 9-11 was not true, I started to question other aspects of our society, our history, the way we were being told things, the way information was being presented to us. And you start to question the sources. And so I became, I underwent the process that a lot of people have gone on since 2020. I underwent it probably around from 2003 onwards. And so when 2020 came, I was already aware that this wasn't going to be true. This was another ruse. This was another means of control. It was part of a larger agenda, which we now know is called Agenda 2030, or it's the World Economic Forum calls it The Great Reset, it is a means of removing our wealth and our, sovereignty to control us. From the very beginning in 2020, I thought something needs to be done about this. I also felt a sense of guilt that the 9-11 truth movement, which I had been a part of, had not done enough. I remember the first day, I was waiting for people to arrive for my class and they did not come. This was before the lockdown, a few days before it was officially announced. I thought, oh my gosh, they are all falling for it, we haven't done enough, I was in a classroom and there was nobody here. I was waiting for people to turn up. I thought this is going to be bad. I had a sense of dread and worry on that day. I was thinking they were really falling for it. I started to be very active very quickly. I emailed everybody I knew on my mailing list for my classes. Everybody, my peers who shared the studios with me. I made my position known, which may have been a mistake professionally and it cost me later because people thought you were spreading the plague, they knew you weren't going to be compliant and so I lost, I was actually forced out of the studio mid-2021 because I wasn't complying with any regulations. But I also got out on the street within about a month. I started making videos, I was making posts routinely anyway about the truth movement. But I'd say it was about April, we started to be, I started to do the first outreach in the streets. I started making videos more to wake up my friends and family and they did actually work, I did get through to my family, they didn't actually, I never like to speak about what they didn't do, but you know what, there was an element of success there, I felt. And so, but in short, I became active. I eventually left Oxford because I'd lost my place of work, which was where I was making my income from I lost that studio because I was forced out in 2021. So I ended up in London in 2022, and I became attached to the Yellow Boards, which is what you were referencing there. And this group, the yellow boards, actually I saw first happening in New Zealand. There was a group of people along a street, a video went round, probably around 2021, late 2021, of people questioning the vaccines and they had yellow boards with slogans on them, like every 50 yards along a stretch of road. And the questions would develop as the driver went past and someone had filmed it from a car. Now this took on in England and also with the rebels, we have a thing called rebels in roundabouts, which started in Stockport. One of the guys there actually said that he'd seen my videos from Oxford and it had helped sort of inspire or encourage him to get out and do that sort of thing. One of the guys who set up the Rebels and Roundabouts. But Yellow Boards is not my invention, it's something that I've, got involved with that was already ongoing by the time I arrived in London in 2022 and so what's happened is sort of, I'm not really an organiser or a maker of flyers and boards and things like like that. So there are very hardworking people who do this. And I seem to be the one who, like an unofficial spokesperson, I'll speak to the camera and I'll speak to people. If someone comes to ask a couple of questions, they'll say, go and speak to him. They'll talk to you. And so that's my role. I just talk to people and present the information as best I can. So your name keeps coming up. Francis O'Neill, you know, yellow boards. Oh, yes. So I want to, there are a couple of things I want to pick up on that, But let me just play some of the clips from around London, just to give the viewers and listeners an idea of what happens in case they have not seen it. So let me just, the first one is, the first one, actually, is Shepherds Bush, I think. Let me see. First one, Shepherds Bush, which I know very well, just around the corner in West London. Let me just play this little clip. And then there are two others from London. (cars beeping in support of yellow boards) So that was Shepherd. Let me do just another one up in Harrow. Shepherd Bush is West London. Harrow is kind of North West and it's the same thing and I want to ask you about kind of that response. You obviously hear the horns beeping on the cars, but here is North West London and Harrow. (Music and cars beeping in support of the yellow boards) We could go on, let me, we could show a lot of them. Can I ask you, when you went out, what were you expecting? We are, many people watching, they'll be engaged in trying to change opinion of those around them. You jump out and do something in the wide world with the public. Tell us about kind of the response you've got and obviously we hear the horns beeping. Is that a regular occurrence? When I first started going out in Oxford in 2020, the response was different. We are talking about lockdowns and people were very hostile. Oxford is like an academic town and has a lot of the research facilities like the Jenner Institute. With regard to that, initially it was very hostile but there were people who were very grateful. Thank God there is somebody who is out there on the street. I felt all alone and I didn't realise other people thought like me. You tend to get a range of those emotions. And we do different subjects obviously, so in London with the yellow boards, the ULEZ , obviously with car drivers, is almost universally unpopular. It is restricting car movement and so on. I think it is also serving to waken people up to the wider problems and agendas I mentioned earlier. With the ULEZ, when we put ULEZ boards up, you tend to get a good response. The good thing about it is, not there are some people who will disagree and they may drive cars because they still think it's in their best interest to have less pollution or whatever the tagline is it seems to vary which I think is very strange as well sometimes it's about an environmental emergency and sometimes it's about children with asthma and obviously it could be about both in theory if it's about clean air, but it's not about clean air because actually if you test the air in London in most places it's very very clean and where they do have hot spots they're not doing anything particular to to solve the pollution in those areas and also on the tube it's up to it's, different studies have said different things like it's 40 times dirtier and people tested maybe have made it higher in terms of the contaminants in the air on the tube so they don't do anything about the air on the tube which is where they're trying to push everybody to go into the public transport but they're concerned about the air where it's actually well within safety standards above ground. And I think people are wise to that. I think people in the cars, they've cottoned on to the fact that this isn't true. So when we go out now, particularly, and it has increased over the time I've been involved, and also obviously since the time it started, but as I say, I can speak from my experience from, 2022, probably mid-2022 in London, even the ULEZ, now it's deafening. You go out there, You get constant car horns. We are not always filming. Sometimes you miss the bits where it is ridiculous, the noise and the cacophony of cars going past. It depends on the location. Sometimes you go to a location that is more muted. And you get more conflicts of opinions where people think that... It is usually people... We are always a bit wary of the cyclists because they sometimes hurl abuse at you. You often get people going past on the bikes as well, tinkling bells going, as in because they don't have a horn obviously on the bicycle so they'll show their support tinkling the bell so so you just can never be sure who's going to say what to you, but the pedestrians... Can be interesting and say things to you. And then you get into dialogue. And sometimes people in the cars will say things like, or like they'll say you're crazy, or I had a guy waving his asthma inhaler at me today. You don't care about me. And I'm saying, well, it's not about air. And I try to explain the things I've just mentioned about how the air is worse on the tube. And when you test the air, it's fine. And it's about control. And I try and make them aware of that. But we all try to be as non-confrontational as possible, but sometimes we get told we're killing children, which is ironic if you actually look at what's going on in the world at the moment. So we're the ones killing children. So yeah, so mixed responses, but overwhelmingly positive about the ULEZ. And I'd actually say we went to the COVID inquiry and we, when Abi Roberts got arrested. And I was surprised given the varied reactions we'd had to COVID lockdown and vaccination outreach that we'd done before, the overwhelming-  Tell us about it, because obviously it started, all of this has started in a pushback towards restrictions under the COVID tyranny. And I know you were there, I know Abi was arrested. We had her on just after, and her talking about how you were waiting outside, waiting for her. And I think you realize who your friends are in situations like that, when you get arrested. Where's everyone gone? Oh, they've gone home, and you waited outside. And that camaraderie, that connection, that networking, that standing shoulder to shoulder has been something that I've seen turning develop over the last three years. I met Abi at one of the marches in London where they have these worldwide rallies for freedom and Abi is a regular at those and I had a mutual friend and said, Abi is going you need to say hello to her. So I said hello to her and you never know if you're going to hit it off with people or whatever. Abi and I were interviewed by somebody came up and interviewed us and we just had like a sort of rapport and it was funny, we were making a bit of a joke with the interviewer and things like this. And so we hit it off and we had a nice conversation and then stayed in touch and just said, like, I'm going down to the COVID inquiry. And I knew that she'd be interested because Matt Hancock, who was our health secretary during the lockdown, was gonna be there that day. And she said, okay, I'll come down. And so she came down to hold a yellow board and make her presence and her opinions known. And she only lasted half an hour.  I understand what you mean when you say Abi making her opinions known, it's beautiful. She wasn't actually that bad, I mean I know that she's very, as in from the police or the establishment perspective, she wasn't that bad, it was just kind of hilarious that she probably lasted about 23 minutes and we had a half-past eight in the morning or something like this in there. And anyway, so she, we walked behind a camera with the yellow board, and we'd been told not to encroach on this space where the camera's filmed. The previous time we'd been at the COVID inquiry, which was about a week before, a few days before. And Abi hadn't been there, so she didn't know, so she just marched in behind and held a board behind one of the reporter's heads. And actually it was a station that she'd previously worked for, the GB News one. So I followed her in and put a board up there and just thought we'll stay here until they move us on. And we did it with Sky TV as well. And then, uh... And she said a few things to the ranks of cameramen and photographers. What have you all been doing? Why are you not reporting anything? And she might have used the F word a couple of times, but nothing too severe, nothing they hadn't heard. And then this guy came out and she's told the story anyway. But yeah, it's on film, you can see. So when she started, when they came to arrest her, I just thought I need to keep my mouth shut because I'll speak over the dialogue and I'll just film it and get a really good footage of it. But then I didn't know whether to put the footage out in case they didn't have any incriminating evidence against her. So I had to sit on the footage until she was released. And then she, there was one moment where I thought the police reacted, I haven't mentioned this before, so in the footage you can see the police, one guy's already told her she's arrested and the others are trying to reason with her, so it didn't really make sense, and they seem to be trying to calm her down and she was saying, do you see this? And she showed one of the badges that she wears for Trudy and whose son committed suicide during lockdown and she was saying, you know, and they, the police, in my first impression of it seemed to recoil at that point. And I thought, oh, wow, that was powerful. Like I was filming it and then, and they seemed to, but when I watched the footage back, I think what actually happened though, he thought was, we can't reason with this woman. They gave up trying to like mollify her and settle it down and stuff. That, cause I thought at first it was the power cause that's what it affected me. And I thought, oh wow, that's got to have an effect. But actually I don't think that's what happened. I just thought that she's, we're going to have to, but they'd already arrested her. So, and then they arrested her and they took her away. And I felt a bit, because I'd invited her down, kind of knowing that she'd provide a bit of fireworks, right? So I felt a bit like, what's the guy? Fagin or something, getting her into trouble. And then she was in the cell. So I felt kind of a responsibility as well. And also thought that if I was in the cell and everyone just went home, I'd come out thinking that's not very nice. So I went down to wait. And also she told me it's only going to be a couple of hours because she'd been given that suggestion. And then as I started to wait and it started to get into the evening, she'd been there 12 hours, the police started to say to me, listen, mate, you're going to have a long wait. And they'd obviously changed the way in which they were going to process her because instead of it just being a basic, you know, you've done a minor misdemeanor, let's get you in and out. They just decided to be awkward and hold her in and charge her in a different way. And they let her out at three in the morning just to be, I think, just to make it unpleasant and uncomfortable for her. So the police became aware of this and rather kindly actually said to me, like, you'll be waiting a long time mate, you should probably go home, she's not going to be let out till the morning. So I had to go and that's what happened. Obviously the whole COVID, well COVID whitewash, not inquiry, but tell us how, because whenever you've been out with boards, it's one thing going with those big demos, where it's that spirit of togetherness and everyone is 100% awake, where you go out on the streets, you kind of expect it to be it to be different. I'm sure going to those demos, I'm sure you've got a lot of pat on the backs and a lot of kind of well done and realizing that people appreciate how you're putting the message out.  Well on the bigger demos, you're amongst a lot of people so there's the strength in numbers and as you say that you can have a chat with people who think the same as you, you still get some people even on the bigger ones if you're on the edges on the peripheries of a group of people marching down a street where people will pull faces or say get lost or shout some abuse at you. You occasionally get that, not normally though because of the numbers because they're slightly intimidated by the numbers. People tend to keep their opinions to themselves when they see thousands of people marching down. You are a little bit more exposed if you go out with a board but generally speaking it's okay. I mean, one of the, connected with the Yellow Boards, I should say, in Stockport, a thing called Rebels on Roundabouts started up at one of the roundabouts in Stockport near Manchester in the north of England. And I went down there a few times, because that's where I'm originally from. And we had eggs thrown at us from a passing car and things like that. And that occasionally happens. But to be honest, most of the time, I don't feel like I'm under threat. I know that sometimes people say nasty things to you and that might, other people might bother them more. I don't really, it doesn't really faze me, I don't think, I don't think it really fazes the people who do it. If people, a lot of the time people are not very brave when they confront you, for example, people will sit there in the car at the lights and when the lights change they'll shout something just as they're going, or the same with a cyclist, so, or if they're passing at speed, so sometimes it's quite funny when they say something to you and then the lights change and they have to stop and then they they sit there like that, or me, cause you can come and say something back then. So yeah, there's not, I don't know. It's not something that concerns me really. Like I think you are going to get people who disagree with you. And I would say my goal and the goal of people there is not to have a confrontation. So if somebody's, sometimes you get people really angry saying you're killing children, you know, it's disgusting. And because we say with ULEZ, they see that as saving children with asthma. Or that's what they've been primed to think. And we say, well, can you explain that? Like, or just, I just try and, or if someone's so in such a heightened state, I just let them carry on walking, or if I can, I'll try and reason with them and bring them down because I learned very quickly, that in 2020, if you go out there, if I go out there and I'm angry, which I was initially in 2020, and start shouting and raving. It's not gonna get anyone on your side. And that's the goal, really. So for the most part, we're there to have reasoned discussion and to share our views and to make people at the very, even if we can't change their minds, obviously, and sometimes you can't do that instantly, is just to make people think, realize that we're not crazy, that we are coming from a reasoned position. And I think that's very important. So we're not, because obviously, they'll say to you, you're a right wing conspiracy theorist, or Sadiq Khan said it. He said, like, you're COVID deniers, vaccine deniers, Tories, all this stuff, like, all the things could think of to say that might be words to lodge in people's brains but the interesting I think I've got a line that I always think of that people, everybody thinks that it's everybody else who falls for propaganda and that includes me so I'll think like oh someone else has fallen, has been brainwashed by the state propaganda but they'll think of me I've fallen for right wing propaganda it's always everybody else who falls for propaganda. It's never me or you know the person thinking so I think that if you can make people aware that there is a different way of looking at things and at least consider it even if you reject it. I think that's a that's all we can do with the yellow boards is to make that we're trying to circumvent mainstream, no mainstream media has censored our point of view so we're trying to find a route to introduce that other point of view in a respectable way to the public.  Yeah it is about making people think and not having that argument because that doesn't actually benefit you. But what about you because I mean it's like a political campaign, I mean I remember back in the days of UKIP, knocking doors, flyers, non-stop and it's about getting the message out and you'd see billboards about different political parties and what you're doing, it's kind of getting the message out, it's PR but it's kind of that field. I mean, how did you, are you, have you been involved politically? Are you a massively outgoing person? Because people think I wouldn't want to stand on a road junction with a huge sign. I mean, people want to keep their thoughts to themselves, not to display it to the world. What was that like. Did you have anything politically background that you had engaged a lot with people on different issues? Not all and I as I say, I started online with the 9-11 truth movement and I used to feel like an imperative. So once you become aware that that say for example, there's a great injustice going on like the war in Iraq or Afghanistan. The removal of our freedoms as well, even if you want to be selfish about it with the in the United States it was the Patriot Act and here we had the terrorism act and you could see the trajectory of of the state machinations then you think well if I do nothing that's going to continue and this isn't going to end well even from a selfish point it's not going to end well for me but I also felt like if I was in Iraq or Afghanistan or any of the other countries affected by the 9-11 wars which have been raging for 20 years so it's like northern Pakistan there's places in Africa and every that being bombed and so and also you've got Syria, Libya, Yemen all these places that have been affected I thought well I'd want someone to at least make a few memes on my behalf in the country. So that's what I used to do. I used to try and make posts and raise awareness and use the internet as many of us are now doing since 2020. So that's what I saw as something that I could contribute. And also I saw myself as being someone who could translate some of the dense material into the language or into the format, like a meme that people would engage with. So I'm not like an academic or a scientist or anything like that. I can read that stuff and think what is the kernel of truth we need to pass on and put that into that format. That is what I thought I could contribute to that movement. In 2020 I tried to do the same thing. That would be the role that I was trying to fulfil. So in terms of getting in the street and presenting that thing, I also think I have done a bit of teaching with the art I was talking about. So you get used to presenting information in front of people and being questioned and you know I've taught in front of kids, I've on in front of pensioners and so I'm not that uncomfortable speaking if I feel like I'm informed, in front of people. So there's that side of it. So maybe I was prepared to do a bit of that. But even if we're just holding a board, I think that was, I read, I think, around 2020 about if you're doing a revolutionary movement, you have to have something that other people can do. So like when we were doing the gazebo, one of the mistakes we probably made is that we would speak to and challenge the police and argue with the police and argue with the public. But not everybody feels that they want to do that. Nobody wants a confrontation really in their life. If you can go through your morning without arguing with the police, you'll probably take that, right? So that's not something that everybody can do and engage what wants to do. But if you do it much simpler, it's more passive. It's just like, you can use a yellow board. Everybody can pretend to be a signpost for a couple of hours, right? Everyone can just be like, oh yeah, I'm just holding this in the street. And it's a more passive way. And the cars are going past. Usually you can stand in a place where the cars aren't gonna stop and they're just whizzed by you and they'll just read your placard. And then you don't actually have to have an argument or a fight, you can just say, there's my board. So it's something that everybody can do is hold a board. You don't have to have read the scientific papers. You don't have to have, you know, you're not like you're arguing with Dr. Fauci or Matt Hancock or something. You can just hold the board and say, where's my freedom going or something. So there's that side of it. And that's something that everyone can do. It's easily replicable. And so you can do that. So the yellow boards have been sprouting up. And I think that's the key. got to give something that everybody can do. So it's that kind of thing. It's just making sure that we get the message out, that's the key thing. And it's not about really presenting to an audience, like in the sense of verbally. And something I've certainly seen is nothing is from the top. I think that's why the police, government, the media are so concerned about free thinking because it's a grassroots thing. You see the yellow boards popping up everywhere, some are organized and some are not and you see the change but I'm intrigued with how people came together on the issue of, against COVID here and the issue of freedom but then you realize that encompasses so much and let me actually, let me play one of the videos of you speaking on, is this the use cash one or is this ULEZ? Let me play it and then we can touch on kind of those other issues which have come up and I think as people have thought more about issues over the last three years they're more open to this but let me play this first one.  (Video of Francis plays) Okay we're here today at Harrow Road and if we take things in reverse and just look at things slightly differently and wonder if there was, in the hypothetical situation, that there was a plan or an agenda to deprive us of our freedoms and to change the way we live. What would it look like and how would they encourage us to consent to it? So, if they can't do it by force because maybe there's a smaller number, they would have to get us to believe that it was for our own good and in our best interest. So, they might then tell us, I don't know, like the end of the world's coming unless you all do what we say, like, you know, like the sky is going to fall on your head or something along those lines. And then they might start to say, what we need for you to do is to use less resources and maybe, Maybe not have a car, maybe lock yourself in your home, maybe we'll bring about some measures so that all independent traders lose their small businesses, so that then you're in the sort of grasp of the state, whether it's because you're on the dole, on a universal credit or whether you're working for corporations which seem to have a lot of control in our country at the moment. So, with that in mind then, people often ask me what it is that they should do, like when, we talk to them about the ULEZ, they say, what should we do about it? Now, what guys say to me with their vans, they say, I'm losing my van, I'm going to have to give up my van and because I've not got my van, I won't be able to work, in which, case I'd be in that situation I've just described. So that's a real problem. So, if you then think about it, there's a guy called Alexander Solzhenitsyn, who ended up in a labour camp in Russia, and old Alexander said, I wish we'd have got out there quicker when they first came to us with iron bars and pots and pans and done something about it. Now, I'm not suggesting you do that, but if you're going to lose your van anyway, and you're going to lose your job anyway, and be in state control, what other options have you got? Some people are using the options of taking down the cameras, and some people are not paying the fines. In fact, millions of pounds apparently are unpaid. Now, if everybody who beeps the horn, as you hear there, did not pay and refused to pay, this scheme would not work and we have to consider that if we're all going to lose everything anyway. I think that's a good point, how people respond. That is on ULEZ, which is obviously the ultra low emission zone, which is in London and attacking the motorist. I think I saw a meme somewhere that someone said, we're told that cars, your older vehicle is going to kill children, but if you pay $12.50 it's okay, the child is saved. It's not about money. But tell us about, because there's been massive support for, against the ULEZ with people cutting down cameras. I didn't think I would see that in Britain, that level of opposition and anger and law breaking. I thought, wow, something's broken in the spirit. It's not just the British shrugging their shoulders, which we think we saw in lockdown, but actually people are doing something. I mean, tell us about that in the response and how you see that push back on the attack on the motorists. Okay, so I want to just say something that I should have said in response to your last question, but I forgot, but you're asking me about the yellow boards and what we're doing that is that what we're trying to do with the yellow boards is do what the government did to us from 2020 onwards. So they put signs everywhere, they put arrows on the floor, they put everywhere you went. So we're trying to make it, they made it ubiquitous. It was just everywhere, like the lockdown was everywhere, you were on a bus, it was on the radio, it was on a screen, it was on a post, everything, public transport, shops, everywhere. You couldn't escape it. If you engaged in life outside your house or even inside your house through the screen, you were made aware that it was this virus and this lockdown and all this stuff and that's what you were supposed to believe. So we have to use that sort of tactic against them and make it feel like, and also what they did is they made everybody feel like everybody believed the same thing. So with the yellow boards, what we're doing is we're presenting a constant stream of, like if you're driving past, you'll see not just one, you'll see 2, 3, 4, 5, 6, 7, 8, 9, 10 yellow boards with these messages and repetitive messages and you'll hear the horns which make you think if you don't agree with us why do all these other people agree? Why are all these horns going off? So it makes you feel like you're the minority which is the reverse of what happened in 2020 when you thought you were the minority if you if you didn't believe the government. So we're using the same sort of tactics there. And so there's that side of it. And also, I think what I'm suggesting in that video is that if you can get someone to blow their horn, then that's an act of defiance, like it's just a little act of defiance. But that's how they got you. First of all, it was like, just three weeks to flatten the curve. Just three weeks, okay, or two weeks in the States. And then it's like, okay, just another three weeks, just a mask. So we're starting off with, just blow your horn. Right? And then if you can hear everyone blowing the horn, then you can think, okay, what's the next step then? Okay, maybe everyone agrees with me, everyone else is blowing the horn, so like, then maybe, maybe, then they take the next act of defiance. Now, we can't volunteer that and suggest that people do that because on video or anything else like that, because it's illegal to encourage people to break the law. All we can do is point to the options, right? And so the response there that you're seeing about the defiance in London, people cutting down the cameras. There are some of us who know, some people say we think we know, but we have read the agenda and it is documented, what this plan is. As you said, it is not about money, they print the money anyway, they can print all the money they want. These people are not short of money, they are not short of control in a way. They are trying to change the nature of humanity, they are trying to control us to, the point where they make us into drones that service the elite class who still fly about, use private planes and cars and whatever else they want and have the dominion over the countryside while we live in smart cities and are boxed in like little rabbit hutches. So if you know that, then as I pointed out there, then you take the Solzhenitsyn idea of grabbing your iron poker or your pots and pans and beating them off in whatever way possible. So if you're still in a system where there is a police force and you can get locked in jail, so what are the small acts of defiance you can do? you can not pay your fine and you can spread crazy foam, you can spray crazy foam over the ULEZ camera. So if you actually know that you're going to lose everything, then spraying foam over a camera is not that big a rebellion. And I think the people who know are taking down the cameras. You know, they realize this is a pivotal moment. This is a bridge that we cannot cross. And so that is why you're seeing that. And whilst it's unusual for the British be so rebellious. We don't really have a history of revolution. If you understand what is happening, this is the time to stand up if there's ever been a time. So that is why the cameras are coming down. Now, not everybody is at that level, and which the people who are know something is not right, they know they can't afford it. And the people in the vans are saying I'm being crushed. And I can't, there's people just drive and say, I won't be able to visit my mom, like I need to get them in the car, or she needs a lift or whatever it is. And there's people who are losing their businesses, because they rely on their van for the business to take all their tools to work and so on. So they know they're losing something. So if we can just nudge them along to, you know, a nudge as in the nudge unit, if we can use that same psychological nudging, you're not alone. Loads of people agree with you. You can be defiant. You can stand up. There's solidarity and it's quite fun to blow your horn and hear the mad noise and it's like it's a kind of, it's a little act of freedom. It's kind of weird because most of the time you you drive your car, you have to obey the code of the road, and you have to be, there's speed restrictions which are coming down all the time to lower and lower speeds. And you are, you know, you don't get this, most people are not in a position where they can just rant and rave at work or at home and support, just you can whack your horn, it's a little moment of freedom, and that feels good. Okay, well, maybe I'll try, and there's loads of it. So we're just trying to get people to recognise the numbers and the strengths, and they have the power. And it might not be as, maybe I'm talking that up a little bit, but I think that somebody has to take some steps somewhere and the more rebellious are taking down the cameras and the less rebellious are blowing the horns and we're hoping they can meet in the middle and just throw the whole thing out. I love that a one-pound thing of silly string or shaving foam can shut down a network of cameras that cost billions. It's beautiful to see that. I think, obviously, whenever you've got a system set up there for taking pictures of cars, automatic number plate recognition, and then that's fed in, that then is a whole surveillance system that is set up. And I think that some people realize that can be used and repurposed for anything but many people don't and you're told oh it just takes a picture and then it disappears and no it's part of a gathering of information on all of us. Do you think people realize that and are wakening up to that?  Yeah I think the harder they push and the more extreme and illogical the measures seem to people, more people look for the reasons behind them. More and more often now, if there is a line of cars and you speak to someone and they say it is madness, he is an idiot, Khan, the mayor of London, they will say he is an idiot. It is not just him though, they're like, yeah I know. Its a bigger thing. They know it is a bigger picture. They have to look at the motive for why it is happening. It doesn't make sense to people. Why would they be crushing us in this way? People tend to understand it is not just about money. and they can also see it. I mean, the surveillance is everywhere. In Britain, we have in the supermarkets, they film your face. So it's, and if you ask, you say, oh, it's about shoplifting, but they're not filming your bag or your hands, they're filming your face. And there's, you know, there's, and to do, interact with, you know, buying tickets or anything like that, you have to give your details and, or to get into your bank account, you need a phone and a laptop or two devices, one to verify the other. So people can see the surveillance state coming in and people can see cash being phased out. So I think people have an awareness that there's something bigger than just they're trying to clean the air for kids with asthma, these guys who don't care about the excess deaths or that nobody makes a peep about wars that kill and displace millions, but they really care about your granny and they really care about the kids with asthma down the street. And also I think to some extent, obviously I don't know enough people to know, but my experience at the COVID inquiry when people responded very positively to our questioning of the COVID vaccines and made me think that the vaccines have woken people up because I think some people will, many people know people who have not had the same health since they took the vaccine. So there's a whole variety of things that are coming together where people think maybe that wasn't quite right that lockdown business and maybe those vaccines weren't quite right and maybe this ULEZ isn't quite right and maybe the phasing out of cash is not quite right and maybe there's a link between them all. So I think that people are coming around to that idea for sure.  Let me just finish off on that cash issue, because here's another clip. We'll play a two minute clip and just finish off just touching on that and the response from people. Because I think a lot of these issues, people maybe can feel that it's too big, it's beyond them. But what you're showing, I think, is each individual can play a part and it's that individuals come together as a mass movement, actually changing things. But let me just play this two minute clip and then we'll finish off just chatting over that. (Video of Francis plays) Okay, today we're here in Hampstead and we've just been giving out a few flyers and raising awareness about the dangers of a cashless economy. I had one woman come up to me and she was asking me about how, what's the point, what's the big deal about it, what's the problem with it, because you know carrying cash is a pain and using card is very convenient. And there is like a Benjamin Franklin quote about foregoing a little bit of liberty for safety, but in our generation we seem to be foregoing liberty for convenience almost. The other day when I was out doing, we were talking about ULEZ, people were saying to me about surveillance. They were saying, oh yeah, well, there's already surveillance everywhere. What difference does it make? And I would make the point to them that the surveillance that I have now, although in Britain we have more cameras per head of population than anywhere except China, is a lot. We have a lot of surveillance. But for the most part, the expense they were talking about was like your mobile phone, reading your emails, tracking you everywhere you go. You can put your mobile phone in the bin, but if you start to have like a smart TV monitor your house, you've got smart car which monitors how you travel and then when you step outside you have surveillance at every zone that they put in for the ULEZ and you then they can control whether or not you spend your money and already in this country you've had people's finances stopped for them saying the wrong things that starts to be a problem and I'm starting to realise a little bit I think that people don't actually know what freedom is or how to defend it I mean they're, talking like for example when we had the vaccines people say no you're still free to get the job but you just have to get the vaccine and they're saying you're still free to go where you want but you just have to you know pay a fine or change your car. These are erosions of freedoms, essential freedoms that we've had for a long time that people don't seem to even understand that what is happening while it's happening around them and there's almost like a complacency. You certainly feel it in some areas where people like maybe smirk at you for carrying a board like this or for talking to them about these kind of subjects that they just don't see the trajectory or the [40:54] fact that once these measures are in place it will be too late to contest them. If they don't go the way they want them to, if suddenly it's their money that's getting stopped, it's only their movements that's getting curtailed. And I think that's something very important that people should consider. But in this country, and I think in the West in general, people feel that their freedom is guaranteed for some reason. I think the thing is that, yeah, most people living in the West haven't lived under a communist system and therefore don't understand freedom as being straight. But that looked like a sunnier day in London. But on that, let's just finish off with this because a lot of these things are an act of change of thinking. We're lulled into something often because it is easier, it is simpler, it makes your life easier. So why you have to go and get cash when you can just touch your phone, soon touch your palm, soon you just walk in and it scans you. But it is people thinking actually intentionally how to push back but how kind of what has been the response from people as you've talked to them and highlighted actually maybe something that people have forgotten that actually it's just easier to have a card or a phone actually you really do need to use cash because as you said if you don't use it it'll be gone.  Well cash is a much more neutral issue for people than say what we talk about lockdown vaccines or ULEZ because the climate agenda and the vaccine or lockdown agendas are firmly lodged. People tend to have a preconceived idea before you reach them. But the cash idea, they're just going to think, well, I've not heard much about that. And then, or they'll say, why do you think that? Or the people who've already onto it, who find it difficult to make their transactions through life using online processes. So yeah, the cash is more neutral and people seem to be more willing to listen to you about that because they're curious or because they hadn't really thought about it. Because it is convenient not to have coins. And if we had a benevolent system and a benevolent government, you know, maybe I'd have no problem with it if you could trust the system. But the fact is that we live in a world where every potential misuse has to be factored in and the government will misuse it to the or somebody at some point will misuse it to the extent to which it's it's possible to misuse it and and that will be to our detriment if we don't have the freedom to spend our cash but I also wanted to say in terms of you mentioned the cameras before on on the ULEZ, introducing the surveillance. That that monitoring that is being brought in. I see a potential threat because you said that we've not had an experience of communism or totalitarianism in this country, but we had it the past three years. I mean, in the Derbyshire Hills, they had drones following people around who were going for a walk on their own, and ordering them home or giving them some kind of police notice for walking in the hills in the countryside. So if you bring in cameras that that can surveil your movement, that those can be, again, misused to the extent to which the state has the potential to misuse them. So if you link all, as I said before, if these things are all linked together, and World Health Organization has a treaty coming in, in which it can override national governments and say if there's the potential for a health emergency, they can impose measures like we've had before, like the quarantines, lockdowns, testing, tracking, tracing, the potential, not the reality of it, just a potential for a health crisis, then you have these zones that are surveilled. If we saw the technology that they had with drones that they use for people in the countryside, if they've got the technology to shut down zones, we already know in this country that they shut down what they call tiers. No, they shut down areas into what they call tiers. Then what would stop them from shutting down an area where they said, oh, this area's had an outbreak because the PCR test, which is not fit for purpose, said that one person, two people had a nosebleed already had a, you know, a cold, they could use the surveillance to shut that down. So I think that the experience of totalitarianism over the past three years has made people more alive, to the fact that these powers can be misused. So when we go out and sort of speak about these things like ULEZ or cash, and you say to them, you might need your freedom sometime, you know, you might need to be able to get into that shopping centre. I mean, in some of the shops, they started to use the one-way arrows on the floor, and some of them had doors with traffic lights on them. So you could go in this door and not this door. It's only one step away from locking you out if they see you as a plague carrying vermin, which is kind of the way they characterize you anyway, because both these schemes, the COVID scheme and the ULEZ scheme, characterized, first of all, they make the air out to be poisoned, as in it's dangerous for you to breathe the air, whether it's ULEZ with cars, and both of them, the people, The agent poisoning the air is the human being. So you are the vermin that is the blight upon the earth and essentially when they say they need to stop the spread, they're talking about people, they need to stop the spread of people, we need to stop them driving around, we need to stay in their homes, we need to stay in the smart cities and all these things. Now people might not have it crystallized in that way in their head but they're aware that something happened over the past three years that was a bit weird and they're aware that they would, that they will remember that it wasn't nice to be locked in their homes or, or prevented from going to shops and supermarkets and nightclubs and pubs and clubs and doing all the normal pleasures of life. So if you start to say to them, the cash could be used in a way, or sorry, the absence of cash could be used in a way to control your purchases or your movements. And would you, I say to them a simple question as well, would you like it if I had control over how you spent your money? Or any other person, like an abusive husband or a wife or a father or whatever, just some third party could say whether or not you spend your money or where and when you spend your money. They can connect with that. They don't want a third party involved with their money. Some people think you're mad, obviously there's still always that range of opinions, but I think that's something that people can very easily identify with. And it's not laden with the same belief system that like belief in the global warming is or in the magic cold that didn't exist for some protests. And did for others or that kind of thing. So it's not laden with that kind of propaganda onslaught. You can just say to them, there's something, cash is your freedom, you need to have control over how you spend your money and they'll go, all right, I hadn't thought of that. Francis, I appreciate you coming on and it's a whole range of issues which have sprung up, COVID tyranny, cash, ULEZ, net zero surveillance, huge issues but love what you do with the yellow boards and I've be looking forward to getting you on. I love having people on who I don't know, I don't never met before and have them on chat so thanks so much for coming on today and sharing what you're doing with the yellow boards. Thank you for having me, Peter. It's been a pleasure.

The world has waited decades for a malaria vaccine, and now two have come along in quick succession. On October 2, the World Health Organization (WHO) recommended that a new malaria vaccine developed by the University of Oxford be rolled out for the prevention of malaria in children, just two years after another vaccine, the RTS,S, got their endorsement. We find out why it's been so hard to find a malaria vaccine – and hear from the scientists behind the new breakthrough. We've been waiting for the official announcement to publish this story, so listeners will hear from former hosts Daniel Merino and Nehal El-Hadi.Featuring Faith Osier, co-director of the Institute of Infections at Imperial College London; Adrian Hill, director of the Jenner Institute at Oxford University, and Alassane Dicko, professor of epidemiology and public health at the Malaria Research and Training Center at the University of Bamako.This episode of The Conversation Weekly was produced and written by Katie Flood. The hosts are Dan Merino and Nehal El-Hadi. The executive producer was Mend Mariwany. Sound design was by Eloise Stevens and our theme music is by Neeta Sarl. Full credits for this episode are available here. A transcript will be available soon. Sign up here for a free daily newsletter from The Conversation.Further reading: How genetically modifying mosquitoes could strengthen the world's war on malariaNigeria has Africa's highest malaria death rate - progress is being made, but it's not enoughHope is on the horizon for a malaria-free Africa Hosted on Acast. See acast.com/privacy for more information.

Meet Discovery Maker Mustapha Bittaye, a postdoctoral researcher at the Jenner Institute who helped create the Oxford AstraZeneca vaccine. Born in The Gambia, a scholarship took Mustapha to the UK to study Microbial Proteomics, and from then onwards he has made truly amazing contributions to human health globally. Conor and Dodi examine Mustapha's story, truly brilliant mind, and how he is looking to the future.

Bret and Heather and Ivermectin.  Oh my. IDSG returns from it's 17 year absence with a banger of an episode in which Daniel dishes out THE FUCKING TEA on Bret Weinstein & Heather Heying (again) and their irresponsible spreading (in hushed, reasonable voices) of potentially lethal conspiracy theories and bad science re Covid, Wuhan, vaccines, and Ivermectin.  Content Warnings. Podcast Notes: Please consider donating to help us make the show and stay independent.  Patrons get exclusive access to one full extra episode a month. Daniel's Patreon: https://www.patreon.com/danielharper Jack's Patreon: https://www.patreon.com/user?u=4196618 IDSG Twitter: https://twitter.com/idsgpod Daniel's Twitter: @danieleharper Jack's Twitter: @_Jack_Graham_ IDSG on Apple Podcasts: https://podcasts.apple.com/us/podcast/i-dont-speak-german/id1449848509?ls=1 Show Notes: Bret Weinstein Odysee Bret interviews Yuri Deigin. Yuri Deigin, Lab Made? SARS-CoV-2 Geneaology Through the Lens of Gain of Function Research Indeed, virologists, including the leader of coronavirus research at the Wuhan Institute of Virology, Shi Zhengli, have done many similar things in the past — both replacing the RBM in one type of virus by an RBM from another, or adding a new furin site that can provide a species-specific coronavirus with an ability to start using the same receptor (e.g. ACE2) in other species. In fact, Shi Zhengli's group was creating chimeric constructs as far back as 2007 and as recently as 2017, when they created a whole of 8 new chimeric coronaviruses with various RBMs. In 2019 such work was in full swing, as WIV was part of a $3.7 million NIH grant titled Understanding the Risk of Bat Coronavirus Emergence. Under its auspices, Shi Zhengli co-authored a 2019 paper that called for continued research into synthetic viruses and testing them in vitro and in vivo: Bret and Heather on Real Time with Bill Mahr on the Lab-Leak Hypothesis CLIP (Bret and Heather on BIll Maher Lab Leak) – starts at beginning of clip. Andersen, et al. The proximal origin of SARS-CoV-2 SARS-CoV-2 is the seventh coronavirus known to infect humans; SARS-CoV, MERS-CoV and SARS-CoV-2 can cause severe disease, whereas HKU1, NL63, OC43 and 229E are associated with mild symptoms6. Here we review what can be deduced about the origin of SARS-CoV-2 from comparative analysis of genomic data. We offer a perspective on the notable features of the SARS-CoV-2 genome and discuss scenarios by which they could have arisen. Our analyses clearly show that SARS-CoV-2 is not a laboratory construct or a purposefully manipulated virus. Garry, Robert. [Early appearance of two distinct genomic lineages of SARS-CoV-2 in different Wuhan wildlife markets suggests SARS-CoV-2 has a natural origin](https://virological.org/t/early-appearance-of-two-distinct-genomic-lineages-of-sars-cov-2-in-different-wuhan-wildlife-markets-suggests-sars-cov-2-has-a-natural-origin/691 This Week in Virology 762: SARS-Cov-2 origins with Robert Garry CLIP (Two Covid Lineages in Wuhan Market) – Starts about 39:00 in TWIV762 potholer54, Did SARS-Cov-2 start in a Chinese Lab? potholer54, More “man-made” SARS-CoV-2 lab-leak malarky Scott Gavura, Science Based Medicine, “Ivermectin is the New Hydroxychloroquine” There has been interest in ivermectin since the early days of the COVID-19 pandemic, because it was observed that at high concentrations it had antiviral properties against the SARS-CoV-2 virus. However, there was an important red flag in that finding. A few weeks after the initial finding was published, a short paper appeared in the British Journal of Clinical Pharmacology that described the considerations for using ivermectin as an antiviral. While it acknowledged the antiviral properties of high concentrations of the drug in laboratory (in vitro) experiments, it noted that it would likely not be possible to achieve the same concentrations of the drug in the plasma of the blood, because the drug itself is tightly bound to blood proteins. Even giving 8.5 x the FDA-approved dose (1700mcg/kg) resulted in blood concentrations far below the dose identified that offered antiviral effects: [[Ivermectin-Cmax.png]] This Week in Virology 766: The Corona Project with David Fajgenbaum CORONA project 18:58, 46:32 “How To Save the World in Three Easy Steps” Clip “Ivermectin End the Pandemic” – starts around 3:30 Bret Weinstein, “COVID, Ivermectin, and the Crime of the Century - DarkHorse Podcast with Pierre Kory & Bret Weinstein” With Dr. Robert Malone (invented mRNA vaccine technology) and Mr. Steve Kirsch. Clip “Bret Doctors as Scientists from CotC” – Starts around 19:00 With Pierre Kory Science Based Medicine, Ivermectin is the new hydroxychloroquine, take 2 Last week, über-quack Joe Mercola published an article entitled “COVID, Ivermectin and the Crime of the Century“, naming it after an episode of Bret Weinstein's podcast. It features an interview with Dr. Pierre Kory, one of the most prominent proponents of ivermectin for COVID-19 by evolutionary biologist Bret Weinstein, who has become prominent as a COVID-19 contrarian and spreader of disinformation, particularly about the “lab leak theory” of SARS-CoV-2 origins and now likes to Tweet about “persecution” by Twitter: It also turns out that Dr. Pierre Kory is president of the Frontline COVID-19 Critical Care Alliance (FLCCC) and has testified before Congress. During that testimony, Dr. Kory claimed that ivermectin, used with other medicines such as vitamin C, zinc and melatonin, could “save hundreds of thousands of people,” and cited more than 20 studies. The narrative of Mercola's article is eerily similar to the narratives we heard about hydroxychloroquine a year ago, namely that ivermectin is a cheap, safe, and effective drug that “they” don't want you to know about that could have saved hundreds of thousands of lives if not for doctors' fetish for randomized clinical trials. Ivermectin is the new hydroxychloroquine, part three Before I move on to more of the ivermectin conspiracy theorists and potential reasons for them, I can't help but repeat what I've been saying all along about ivermectin. Combining preclinical studies that show antiviral activity against SARS-C0V-2, the coronavirus that causes COVID-19 in vitro (cell culture) but only at much higher concentrations of ivermectin than can be achieved with safe doses in the bloodstream with the equivocal clinical trial results lead to a conclusion that this drug almost certainly does not work to treat COVID-19. This is particularly likely given that the highest quality existing randomized controlled clinical trials of ivermectin are all basically negative. I note that when I discussed how poor the evidence for hydroxychloroquine for COVID-19 was, I routinely received criticism that I “wanted patients to die” and was “hoping” that the drug didn't work. I'm getting some of the same nonsense now that I've finally been prodded to write about ivermectin. Nothing could be further from the truth. Even though, now that there are safe and effective COVID-19 vaccines, the need for a cheap and effective drug that can treat COVID-19 is not as desperate as it was a year ago, it is still acute given how large swaths of the globe still do not have access to the vaccines. Moreover, now that Oxford University has added ivermectin to the protocol of its massive PRINCIPLE Trial of treatments for COVID-19, it is possible that there might turn out to be a benefit due to ivermectin in treating COVID-19, clearly just not as massive as claimed by advocates and conspiracy theorists. I'd be just fine with that, as I would have been overjoyed if hydroxychloroquine had been shown to be as effective as its advocates had claimed it was. It's just that, right now, the evidence is trending strongly in favor of the conclusion that ivermectin, like hydroxychloroquine before it, doesn't work against COVID-19 in humans. Gideon M-K; Health Nerd What this means is that, if you exclude some of the low-quality research on ivermectin, the paper goes from showing a massive benefit to no benefit at all. On top of this, there's an interesting point — even if you don't agree with these assessments, taking the only three studies that the authors of the meta-analysis considered to be at a “low risk of bias” (i.e. high-quality), you find that these high-quality studies have failed to find any benefit for ivermectin. In other words, while the conclusions the authors came to are very positive, the results section of the paper seems to show that the evidence for ivermectin might not be strong after all. The devil really is in the details with research like this. Jack Lawrence aka TimPoolClips Why Was a Major Study on Ivermectin for COVID-19 Just Retracted? Even if the paper's authors end up providing an innocent explanation for all this it would be puzzling why it took them so long to notice their error. Whether the final story is one of purposeful fabrication or a series of escalating mistakes involving training or test datasets, this research group has still screwed up in a big way. Although science trends towards self-correction, something is clearly broken in a system that can allow a study as full of problems as the Elgazzar paper to run unchallenged for seven months. Thousands of highly educated scientists, doctors, pharmacists, and at least four major medicines regulators missed a fraud so apparent that it might as well have come with a flashing neon sign. That this all happened amid an ongoing global health crisis of epic proportions is all the more terrifying. For those reading this article, its findings may serve as a wake-up call. For those who died after taking a medication now shown to be even more lacking in positive evidence, it's too late. Science has corrected, but at what cost? Ivermectin is the new hydoxychloroquine, take four Of course, as Meyerowitz-Katz observed, just the results of the study raised a lot of red flags. Elgazzar 2020, if you take the authors at their word, enrolled over 400 people with COVID-19 and 200 close personal contacts and allocated them either to ivermectin or placebo groups, reporting that ivermectin treatment decreased mortality from COVID-19 by a whopping 90%. As Meyerowitz-Katz observed, if this were true, that would make ivermectin the “most incredibly effective treatment ever to be discovered in modern medicine.” While as a physician I might quibble about that a bit (we do have treatments that are greater than 90% effective at eliminating the diseases or conditions that they treat, especially a number of vaccines), he is correct if you restricted this to antiviral drugs. If this study's results were accurate and generalizable, ivermectin would be the most most incredibly effective antiviral treatment ever to be discovered. That result alone should have raised a number of red flags, and it did among authors doing meta-analyses who were not ivermectin advocates from the BIRD Group or the FLCCC, which is why they excluded it from their analyses. Meilssa Davey at The Guardian Huge sttudy supporting ivermectin as Covid treatment withdrawn over ethical concerns A medical student in London, Jack Lawrence, was among the first to identify serious concerns about the paper, leading to the retraction. He first became aware of the Elgazzar preprint when it was assigned to him by one of his lecturers for an assignment that formed part of his master's degree. He found the introduction section of the paper appeared to have been almost entirely plagiarised. It appeared that the authors had run entire paragraphs from press releases and websites about ivermectin and Covid-19 through a thesaurus to change key words. “Humorously, this led to them changing ‘severe acute respiratory syndrome' to ‘extreme intense respiratory syndrome' on one occasion,” Lawrence said. The data also looked suspicious to Lawrence, with the raw data apparently contradicting the study protocol on several occasions. “The authors claimed to have done the study only on 18-80 year olds, but at least three patients in the dataset were under 18,” Lawrence said. Dark Horse 85: YouTube and The Truman Faux Medical Show CLIP “DH85 Save Three Kill Two” – Starts Around 50:00 Dark Horse 86: They've Got That Covered CLIP “DH86 Retraction” – Starts around 19:00 “Scientists quit journal board, protesting ‘grossly irresponsible' study claiming COVID-19 vaccines kill” Several reputed virologists and vaccinologists have resigned as editors of the journal Vaccines to protest its 24 June publication of a peer-reviewed article that misuses data to conclude that “for three deaths prevented by [COVID-19] vaccination, we have to accept two inflicted by vaccination.” Since Friday, at least six scientists have resigned positions as associate or section editors with Vaccines, including Florian Krammer, a virologist at the Icahn School of Medicine at Mount Sinai, and Katie Ewer, an immunologist at the Jenner Institute at the University of Oxford who was on the team that developed the Oxford-AstraZeneca COVID-19 vaccine. Their resignations were first reported by Retraction Watch. “The data has been misused because it makes the (incorrect) assumption that all deaths occurring post vaccination are caused by vaccination,” Ewer wrote in an email. “[And] it is now being used by anti-vaxxers and COVID-19-deniers as evidence that COVID-19 vaccines are not safe. [This] is grossly irresponsible, particularly for a journal specialising in vaccines.” The paper is a case of “garbage in, garbage out,” says Helen Petousis-Harris, a vaccinologist who directs the Vaccine Datalink and Research Group at the University of Auckland and who also resigned as a Vaccines editor after reading the paper. Diane Harper, an epidemiologist at the University of Michigan, Ann Arbor, who was founding editor-in-chief of Vaccines, also resigned, as did Paul Licciardi, an immunologist at Murdoch Children's Research Institute in Parkville, Australia, and Andrew Pekosz, a respiratory virologist at the Johns Hopkins University Bloomberg School of Public Health. Epoch Times, Dr. Bret Weinstein, “Perverse Incentives in the Vaccine Rollout and the Censhorship of Science” * Anna Merlan at Vic; two excellent summaries: 1. 'Why Is the Intellectual Dark Web Suddenly Hyping an Unproven COVID Treatment?' https://www.vice.com/en/article/wx5z5y/why-is-the-intellectual-dark-web-suddenly-hyping-an-unproven-covid-treatment 2. 'The Ivermectin Advocates' War Has Just Begun' https://www.vice.com/en/article/y3d5gv/ivermectin-covid-treatment-advocates-rogan-weinstein-hecker Jef Rouner at Houston Press on Bret https://www.houstonpress.com/news/a-possible-new-anti-vaccine-scam-is-on-the-rise-11591162 Decoding the Gurus on Bret & Heather and Ivermectin https://decoding-the-gurus.captivate.fm/episode/brett-heather-weinstein-why-are-they-suppressing-ivermectin-the-miracle-cure Bret platforms Geert Vanden Bossche https://www.youtube.com/watch?v=BNyAovuUxro&t=6s Vaxopedia on Geert Vanden Bossche https://vaxopedia.org/2021/03/14/who-is-geert-vanden-bossche/?fbclid=IwAR3u1myW15pERVxvcopv5NlWBr12QakfzVMHsoHHopLuJWKSUGfockqYhBo ZDoggMD on Geert Vanden Bossche https://www.youtube.com/watch?v=NEyQi__zTuo Potholer54 on Covid and vaccines etc https://www.youtube.com/playlist?list=PL82yk73N8eoWneZjR0wiidhGkAMOeIYAS QAnon Anonymous feat. scientist on 'Lab Leak' theory https://soundcloud.com/qanonanonymous/unlocked-premium-episode-129-lab-leak-hypothesis-feat-dr-alex-greninger Citations Needed Pod vaccine inequality https://citationsneeded.libsyn.com/size/5/?search=vaccine Clip from start; Charlie Kirk cites Bret to Tucker Carlson https://twitter.com/uberfeminist/status/1418033997398020102 Eiynah's panel on 'Mergegate' (feat. D. Harper) Part 1 https://soundcloud.com/politeconversations/panel-24-defending-new-atheism-maybe-just-dont-pt-1 Daniel's guest appearance on Decoding the Gurus https://decoding-the-gurus.captivate.fm/episode/special-episode-interview-with-daniel-harper-on-the-far-right-idw-criticism  

Shuailin Li, a PhD Student at the Jenner Institute in the group of Prof Helen McShane, studies the link between cytomegalovirus (CMV) infection and M.tuberculosis infection or tuberculosis(TB) disease. Infections rarely, if ever, happen in isolation: humans are infected with 10 chronic viruses on average and this imprint shapes our response to other pathogens. On this episode, find out how data from a vaccine study cohort uncovered a detrimental association between CMV infection and TB, the likely immunological mechanisms for this effect and the possible implications of these findings in endemic regions.

A new vaccine could help eliminate the disease. What would that mean for African economies? Manuela Saragosa speaks to the man who led the team behind the new vaccine, which has demonstrated a startling 77% effectiveness in recent drug trials. Adrian Hill of Oxford University's Jenner Institute says it is the culmination of 20 years' work - but how was it all funded? Research suggests malaria has been one of the biggest factors that historically held back African economies, according to Obinna Onwujekwe, professor of health economics at the University of Nigeria. But the big pharmaceutical companies have had no commercial interest in developing a vaccine, says Els Torreele of University College London. Producer: Laurence Knight (Picture: Mosquito; Credit: Getty Images)

Analysis of the 78,0000-year-old fossil of a Kenyan boy reveals he was likely buried with care and attention, the body wrapped and laid to rest supported on a pillow. Maria Martinon-Torres, of the National Research Centre on Human Evolution in Burgos, Spain, and a team from Kenya and Germany used techniques from paleontology and forensic science to reveal his story from the fragile remains. A promising malaria vaccine is to enter trials which could lead to it being used globally to vaccinate children. Merheen Datoo, Oxford University’s Jenner Institute, explains malaria vaccines have been in development for 100 years. Research from these helped covid vaccine development and the success of covid vaccines may now help to speed up the rollout of malaria vaccines. Covid vaccines may also help to treat those who have symptoms of long covid – a range of immune system issues that develop sometimes months after the initial infection. Yale University immunologist Akiko Kawasaki is embarking on a research project to assess the impact. If you’d like to take part, have yet to be vaccinated, and live in Connecticut in the US, email covidrecovery@yale.edu. And in India scientists are calling on the government to make all data on Covid more widely available. At present Indian bureaucracy means statistics on infection rates, variants and recovery are not distributed widely. Science journalist TV Padma says greater access to the data could help more scientists come together to work on solutions to India’s Covid crisis. And, Have you taken classes to learn a new sport or musical instrument or a language? It’s hard work! Why is it that as children we effortlessly absorb new skills and we don’t as adults? That’s what 50-something listener Gary Grief wondered about playing guitar. Do you need to play more frequently as an adult to attain the same level of expertise? Does the 10,000-hours theory still apply? Presenter and budding tabla-player Anand Jagatia embarks on a musical journey to discover what neuroscience can tell us about muscle memory and learning. Do musicians and sportsmen share the same challenges? By understanding what’s happening in the brain, can we learn how to learn better? With tabla-teacher Satvinder Sehmbey, neuroscientist Dr Jessica Grahn, viola-player Dr Molly Gebrian and sports scientist Prof Yannis Pitsiladis. (Image: An artist’s interpretation of Mtoto’s burial Credit: Fernando Fueyo)

Analysis of the 78,0000-year-old fossil of a Kenyan boy reveals he was likely buried with care and attention, the body wrapped and laid to rest supported on a pillow. Maria Martinon-Torres, of the National Research Centre on Human Evolution in Burgos, Spain, and a team from Kenya and Germany used techniques from paleontology and forensic science to reveal his story from the fragile remains. A promising malaria vaccine is to enter trials which could lead to it being used globally to vaccinate children. Merheen Datoo, Oxford University’s Jenner Institute, explains malaria vaccines have been in development for 100 years. Research from these helped covid vaccine development and the success of covid vaccines may now help to speed up the rollout of malaria vaccines. Covid vaccines may also help to treat those who have symptoms of long covid – a range of immune system issues that develop sometimes months after the initial infection. Yale University immunologist Akiko Kawasaki is embarking on a research project to assess the impact. If you’d like to take part, have yet to be vaccinated, and live in Connecticut in the US, email covidrecovery@yale.edu. And in India scientists are calling on the government to make all data on Covid more widely available. At present Indian bureaucracy means statistics on infection rates, variants and recovery are not distributed widely. Science journalist TV Padma says greater access to the data could help more scientists come together to work on solutions to India’s Covid crisis. (Image: An artist’s interpretation of Mtoto’s burial Credit: Fernando Fueyo) Presenter: Roland Pease Producer: Julian Siddle

Stories about the development of COVID-19 vaccines have dominated the news for months, but a huge breakthrough in the prevention of another infectious disease has just been announced. Listen to this episode to learn about a new malaria vaccine developed by researchers at the Jenner Institute at the University of Oxford that is 77 percent effective at blocking the parasite.In this episode, Ayesha also shares the results of a study that gives parents another reason to limit their kids' sugar intake. Research involving rats has identified a mechanistic link between high sugar consumption and impaired learning and memory later in life that involves a specific genus of gut bacteria. The team discusses the challenges of regulating added sugar in processed foods, and the applicability of animal models in understanding human development. Read the full articles here:Malaria Vaccine a Breakthrough Success with 77 Percent Efficacy How Sugar May Impair Brain Development in ChildrenFor more life science and medical device content, visit the Xtalks Vitals homepage.Follow Us on Social MediaTwitter: @Xtalks Instagram: @Xtalks Facebook: https://www.facebook.com/Xtalks.Webinars/ LinkedIn: https://www.linkedin.com/company/xtalks-webconferences YouTube: https://www.youtube.com/c/XtalksWebinars/featured

Adrian Hill, The director of the Jenner Institute at the University of Oxford, discusses how Germany has handled the rollout of the AstraZeneca vaccine.

It’s the science story of the century - how successful vaccines against Covid-19 have been created in under a year. Mark explores the back-story on how they did it so quickly with Dr Anthony Fauci, Director of the NIAID and Sarah Gilbert from the Jenner Institute, Oxford. He gets the low down on the vaccine science from scientist Rob Swanda and he talks vaccines vs. variants with Wendy Barclay from Imperial College London. Hosted by Mark Honigsbaum @honigsbaum With Anthony S. Fauci, M.D., NIAID Director www.niaid.nih.gov/about/director Professor Sarah Gilbert, Saïd Professorship of Vaccinology, Jenner Institute & Nuffield Department of Clinical Medicine www.jenner.ac.uk/team/sarah-gilbert Rob Swanda @ScientistSwanda / Youtube: www.youtube.com/channel/UClU56Y1m8J9w82itIEXEHFQ?view_as=subscriber Professor Wendy Barclay, Action Medical Research Chair Virology, Imperial College London. www.imperial.ac.uk/people/w.barclay Series Producer: Melissa FitzGerald @Melissafitzg Cover art by Patrick Blower www.blowercartoons.com Follow us on Twitter @GoingViral_pod      Follow us on Instagram: goingviral_thepodcast

It’s the science story of the century - how successful vaccines against Covid-19 have been created in under a year. Mark explores the back-story on how they did it so quickly with Dr Anthony Fauci, Director of the NIAID and Sarah Gilbert from the Jenner Institute, Oxford. He gets the low down on the vaccine science from scientist Rob Swanda and he talks vaccines vs. variants with Wendy Barclay from Imperial College London. Hosted by Mark Honigsbaum @honigsbaum With Anthony S. Fauci, M.D., NIAID Director www.niaid.nih.gov/about/director Professor Sarah Gilbert, Saïd Professorship of Vaccinology, Jenner Institute & Nuffield Department of Clinical Medicine www.jenner.ac.uk/team/sarah-gilbert Rob Swanda @ScientistSwanda / Youtube: www.youtube.com/channel/UClU56Y1m8J9w82itIEXEHFQ?view_as=subscriber Professor Wendy Barclay, Action Medical Research Chair Virology, Imperial College London. www.imperial.ac.uk/people/w.barclay Series Producer: Melissa FitzGerald @Melissafitzg Cover art by Patrick Blower www.blowercartoons.com Follow us on Twitter @GoingViral_pod      Follow us on Instagram: goingviral_thepodcast If you enjoy these podcasts, please leave us a rating or review.  Thank you.

Professor Adrian Hill, director of the Jenner Institute at Oxford, speaks to Sarah about the development of the AstraZeneca vaccine.

On New Year’s Eve 2020, Mark took his mum to St Charles’s Hospital in London’s North Kensington to get a shot of the new Pfizer-BioNTech vaccine, almost a year after the coronavirus had emerged in Wuhan. It’s the science story of the century - how successful vaccines against Covid-19 have been created in under a year. Mark explores how they did it so quickly with Adrian Hill, Director of the Jenner Institute in Oxford behind the Oxford-AstraZeneca vaccine. And against the backdrop of global vaccine hesitancy, and as Covid-19 cases surge in Britain’s second wave, Mark speaks to Peter Openshaw from Imperial College London about the magic of vaccines. Hosted by Mark Honigsbaum @honigsbaum With Professor Adrian Hill, Lakshmi Mittal and Family Professorship of Vaccinology; Director of the Jenner Institute; Co-Director, Oxford Martin Programme on Vaccines; Fellow of Magdalen College. www.ox.ac.uk/news-and-events/find-an-expert/professor-adrian-hill Peter Openshaw Professor of Experimental Medicine at Imperial College at Imperial College, London. www.imperial.ac.uk/people/p.openshaw / @p_openshaw Series Producer: Melissa FitzGerald @Melissafitzg Cover art by Patrick Blower www.blowercartoons.com Follow us on Twitter @GoingViral_pod      Follow us on Instagram: goingviral_thepodcast If you enjoy these podcasts please leave us a rating or review - thank you.

On New Year’s Eve 2020, Mark took his mum to St Charles’s Hospital in London’s North Kensington to get a shot of the new Pfizer-BioNTech vaccine, almost a year after the coronavirus had emerged in Wuhan. It’s the science story of the century - how successful vaccines against Covid-19 have been created in under a year. Mark explores how they did it so quickly with Adrian Hill, Director of the Jenner Institute in Oxford behind the Oxford-AstraZeneca vaccine. And against the backdrop of global vaccine hesitancy, and as Covid-19 cases surge in Britain’s second wave, Mark speaks to Peter Openshaw from Imperial College London about the magic of vaccines. Hosted by Mark Honigsbaum @honigsbaum With Professor Adrian Hill, Lakshmi Mittal and Family Professorship of Vaccinology; Director of the Jenner Institute; Co-Director, Oxford Martin Programme on Vaccines; Fellow of Magdalen College. www.ox.ac.uk/news-and-events/find-an-expert/professor-adrian-hill Peter Openshaw Professor of Experimental Medicine at Imperial College at Imperial College, London. www.imperial.ac.uk/people/p.openshaw / @p_openshaw Series Producer: Melissa FitzGerald @Melissafitzg Cover art by Patrick Blower www.blowercartoons.com Follow us on Twitter @GoingViral_pod      Follow us on Instagram: goingviral_thepodcast

The UK has given the green light to the Oxford AstraZeneca Covid19 vaccine. It’s cheaper and easier to store than some of the alternatives - and the hope is that will make it easier to distribute globally. However, there are worries that production capacity and an unwillingness to share intellectual data might mean the poorest in the world won’t get the immunisation. We speak to Anna Marriott of Oxfam. Also on the show we’ll be mulling over the Brexit deal. We get the view from businesses both sides of the Channel about what the future will bring now the UK and EU have a new trade relationship. We also hear from former EU trade commissioner Cecilia Malmstrom who tells us what effect the divorce will have on the rest of the union. As the rest of the world continues to struggle with Covid 19, China is getting back to normal. We hear from Wuhan and Shanghai. Plus, food businesses discuss how they’ve adapted to survive during the pandemic. Business Weekly is presented by Lucy Burton and produced by Clare Williamson. (Image:University of Oxford researcher in a laboratory at the Jenner Institute, working on the coronavirus vaccine. Image credit: John Cairns/University of Oxford/PA Wire)

TESTO DELL'ARTICOLO ➜http://www.bastabugie.it/it/articoli.php?id=6409IL ''NUOVO'' CORONAVIRUS INGLESE CI CONDANNA AD UNA SITUAZIONE DI EMERGENZA FINO AL 2025Stessi sintomi, stesse cure e probabilmente stesso vaccino, ma serve per mantenere il clima di terrore per giustificare nuovi lockdowndi Paolo GulisanoLo scrivevamo poco tempo fa, prendendo spunto da un articolo di Science: la crisi pandemica è destinata a durare fino al 2025.Le notizie arrivate dall'Inghilterra hanno cominciato ad essere utilizzate per aumentare il tasso di paura nella popolazione che è già di per se altissimo: una "variante" del Sars-Cov 2 è stata identificata in Gran Bretagna, e il primo aspetto che è stato enfatizzato è la sua rapidità di trasmissione, che sarebbe fino al 70 per cento più elevata del virus finora dominante. Il condizionale è d'obbligo, perché cosa sappiamo di questa cosiddetta variante inglese del Covid-19? È più mortale o più grave del ceppo originale? Quali sono i sintomi e le differenze tra i due? Al momento le informazioni disponibili suggeriscono che la nuova variante di Covid scoperta in Inghilterra causa gli stessi sintomi del ceppo originale. Chi contrae il virus può quindi avere febbre, tosse secca e stanchezza o anche dolori muscolari, gola infiammata, mal di testa, congiuntivite, diarrea, perdita di gusto e olfatto. Insomma gli stessi sintomi del ceppo virale identificato quasi un anno in Cina. Compresi i sintomi gravi, come la difficoltà respiratorie.Questo è ciò che proviene come informazioni dalle autorità inglesi. Tuttavia la notizia è esplosa in modo psicologicamente devastante proprio perché fa pensare all'opinione pubblica che dall'incubo pandemico non ci libereremo mai. Nuovi ceppi virali vogliono dire nuovi lockdown, nuove emergenze ospedaliere, il reiterarsi insomma degli scenari che abbiamo già conosciuto. E questo nuovo incubo ha un nome che evoca scenari distopici o fantascientifici: mutazioni.LE MUTAZIONI VIRALI SONO NORMALIIn realtà le mutazioni virali sono un evento che non ha nulla di eccezionale, perché sono frequenti, quasi la norma in microbiologia. Di fatto ci sono già state varie mutazioni di Covid-19 che si sono diffuse. Non si vede dunque il perché di questa frettolosa enfatizzazione del pericolo del New British Covid. Semmai questo allarme dovrebbe far riflettere sui rischi di quelle scelte riguardanti le terapie da utilizzare contro il Covid-19 che possono aver selezionato un nuovo ceppo e prodotto la mutazione. Un'ipotesi preoccupante che si fa tra i ricercatori inglesi è che le mutazioni si siano sviluppate in un paziente affetto da Covid-19 per circa due mesi e curato con l'antivirale remdevisir, che potrebbe avere selezionato un virus in grado di sfuggire alle terapie.Posto che - come sembra - la variante d'Oltremanica non sia più grave di quella fattaci pervenire lo scorso anno della Cina, ci sono però una serie di interrogativi riguardanti i nuovi scenari epidemiologici che potrebbero andare a configurarsi. In primo luogo: è possibile riconoscere il nuovo ceppo mutato e distinguerlo da quello originale? Con il test sierologico certamente sì, ma con i tamponi al momento nella stessa Inghilterra non è possibile individuare specificamente la nuova variante.Quindi - almeno per un po' di tempo - il virus venuto da Albione rappresenterà soprattutto una minaccia fantasma, utile però per rinfocolare la paura e giustificare nuovi lockdown. NULLA CAMBIA PER I VACCINILa domanda cruciale poi che molti si pongono è: cosa cambia per i vaccini? Nulla, è la risposta. La road map dell'organizzazione vaccinale prosegue - lei sì - senza alcuna mutazione. Dal presidente del Consiglio superiore di sanità Franco Locatelli al virologo Fabrizio Pregliasco, a Giacomo Gorini, ricercatore dello Jenner Institute dell'Università di Oxford, sono arrivate immediatamente ferme e sicure rassicurazioni: i vaccini predisposti contro il Coronavirus dovrebbero mantenere la loro efficacia.Tuttavia, secondo un importante immunologo, il professor Andrea Cossarizza, è assolutamente prematuro ipotizzare se la mutazione possa inficiare l'effetto del vaccino. «Dobbiamo basarci su evidenze scientifiche di cui oggi non siamo in possesso», ha affermato. In realtà sappiamo bene che esistono virus, come quelli influenzali, che mutano continuamente e che di conseguenza fanno sì che ogni anno si debbano mettere a punto nuovi vaccini. Potrà essere questo lo scenario futuro del Covid? Diventare un virus stagionale che muta anno per anno, e che ogni anno richiede milioni di nuove vaccinazioni? Potrebbe essere. A questo punto però è lecito chiedersi, di fronte ad un virus con queste caratteristiche, se la soluzione vera non stia nella ricerca sui farmaci che possano efficacemente curare il Covid, in tutte le sue possibili versioni mutate. Una soluzione più semplice e a portata di mano con le scoperte e le evidenze scientifiche in materia di terapia che stanno emergendo.Nota di BastaBugie: l'autore del precedente articolo, Paolo Gulisano, nell'articolo seguente dal titolo "Covid fino al 2025, l'assist di Science per il Grande Reset" spiega che tale affermazione non è sostenuta da nessuna evidenza medica e cozza con la storia delle grandi epidemie. Tutto è funzionale a mantenere il clima di terrore, con inevitabili conseguenze sul piano economico, politico e anche antropologico.Ecco l'articolo completo pubblicato su La Nuova Bussola Quotidiana il 19 dicembre 2020:Da qualche tempo si parla di Great Reset: il grande rivolgimento economico, sociale, politico, mondiale che è stato avviato utilizzando l'epidemia di Covid. Complottismo? Decisamente no. Basta andare a guardare il numero del 13 novembre dell'importante rivista Science per capire che il Covid, se non ci fosse, bisognerebbe proprio inventarlo, tanto è utile ai grandi cambiamenti, che necessariamente richiedono tempo. E così Science ci dice che l'emergenza Covid durerà fino al 2025, e che fino a tutto il 2022 si dovranno mettere in atto provvedimenti restrittivi delle libertà.Da un punto di vista strettamente medico, è un'affermazione quantomeno singolare. Le grandi epidemie del passato, dalla Spagnola all'Asiatica, fino alla Sars del 2002, non sono mai durate più di un anno. Per quale motivo questo virus dovrebbe continuare a circolare imperterrito per altri cinque anni? Non viene data alcuna spiegazione scientifica. È una mera ipotesi, che va contro l'evidenza di tutta la storia delle epidemie.Ma il vaccino? Non sarà lui, come ci viene annunciato da tempo, a liberare il mondo dal grande incubo? Non è detto, ci dice Science. Gli esseri umani sono infettati da diversi coronavirus stagionali con reazioni crociate. Nessuno provoca un'immunità completamente protettiva e le infezioni ripetute sono la norma. I vaccini tendono ad essere meno efficaci delle infezioni naturali nel provocare l'immunità e ci sono rischi di reazioni crociate avverse. Un ricercatore, Chadi M. Saad-Roy, ha quindi utilizzato una serie di modelli semplici per una varietà di scenari immunitari per prevedere futuri immunologici per la Sars-Cov-2, con e senza vaccini. I risultati del modello mostrano che la nostra conoscenza imperfetta del panorama immunitario imperfetto del coronavirus può dare origine a scenari divergenti che vanno dalle epidemie gravi ricorrenti all'eliminazione.Sì, alla fine il Covid dovrebbe sparire, ma - ci viene detto - ci vorranno cinque anni. Il tempo di una guerra, più o meno la durata della Prima (1914-1918) e della Seconda Guerra Mondiale (1939-1945). Fino al 2025 dovremmo vivere nella paura, nel terrore. E questo piano quinquennale avrà inevitabili conseguenze economiche e politiche, ma anche psicologiche e perfino antropologiche, a nostro avviso. Il Grande Reset, appunto.Secondo lo studio in questione, le misure di allontanamento sociale come le restrizioni alle riunioni pubbliche potrebbero dover rimanere in atto a intermittenza per almeno un altro paio di anni per contenere la diffusione del Covid-19. Queste dure misure che hanno già spinto l'economia mondiale in recessione potrebbero essere necessarie perché, secondo le proiezioni dei ricercatori, nuovi focolai di Sars-Cov-2 potrebbero (il condizionale è d'obbligo) ripresentarsi ogni inverno.Ancora, e i vaccini? I ricercatori ammettono che potrebbero rivelarsi non sufficientemente efficaci. Almeno fino al 2024. Secondo lo studio, le ricorrenti epidemie invernali di Sars-Cov-2 si verificheranno nel corso dei prossimi anni dopo l'iniziale ondata pandemica più grave. Quindi, secondo le proiezioni dei ricercatori, che curiosamente escludono qualsiasi scoperta farmacologica atta a curare il virus, oltre a negare - ma questo sappiamo che è parte del pensiero mainstream - possibilità di trattamenti già esistenti, e persino mettendo appunto in dubbio l'immediata efficacia dei vaccini, non resta che continuare il distanziamento intermittente.È molto probabile che tali modelli teorici verranno presto tradotti a livello internazionale in strategie di azione sanitaria ma anche in politiche economiche. Ciò avrà come conseguenza uno stato di guerra permanente, uno sconvolgimento della vita di milioni di persone, costrette a vivere con sempre minori libertà, aspettando che si formi un'immunità di gregge tale da far dichiarare cessato il pericolo. Anche se non è da escludere che la micidiale minaccia di nuove sedicenti epidemie non venga continuamente sbandierata da chi ne ha tutto l'interesse. È il caso di Mark Dybul - uno stretto collaboratore del mitico virologo americano Anthony Fauci - che nei giorni scorsi ha parlato di prossime future nuove pandemie.Insomma, il clima di terrore e insicurezza deve continuare, e per i prossimi cinque anni la parola Covid non scomparirà affatto. Il tutto, lo ribadiamo con forza, contro ogni evidenza, perché in realtà il Covid potrebbe estinguersi in breve tempo come hanno fatto prima di lui tutti i virus pandemici.

The head of the World Health Organisation, Tedros Adhanom Ghebreyesus, has welcomed the promising trial results of a new coronavirus vaccine, but says the poor must not be trampled in the stampede for protection. We'll hear from the director of the Africa Centres for Disease Control and Prevention. Also in the programme: Joe Biden has chosen a veteran US foreign policy official with internationalist views, Antony Blinken, to be his Secretary of State; and did the Israeli Prime Minister, Binyamin Netanyahu, fly to Saudi Arabia to meet Crown Prince Mohammed bin Salman? (Picture: A researcher at the University of Oxford's Jenner Institute working on the coronavirus vaccine developed by AstraZeneca and Oxford University. Credit: John Cairns/University of Oxford/PA Wire)

Another promising trial result shows the Oxford AstraZeneca vaccine is highly effective. We hear from Dr Theresa Lambe of the Jenner Institute in Oxford, who was involved in the vaccine's development, that whilst results indicate it is not as effective as two other vaccines, it is likely to be cheaper, and will be easier to distribute. Also in the programme, despite a sharp drop in carbon emissions in the first half of the year as a result of the coronavirus pandemic, overall carbon dioxide levels continue to rise, albeit at a reduced rate. We get reaction from Simon Birkitt, director of the activist organisation Clean Air in London. The BBC's Tamasin Ford reports on a rapidly developing financial technology, or fintech, sector in Africa. Plus, with sales of loungewear up as a result of many people working from home, we find out more from Tamara Sender Ceron, senior fashion analyst at Mintel. (Picture: Vials waiting to be filled with Oxford vaccine. Picture credit: Getty Images.)

Around the world, women are at the forefront of research on a Covid vaccine. One of those scientists is Dr. Alex Spencer, an immunologist at Oxford University's Jenner Institute. Hear what she has to say about research and women in science, and why she's optimistic. Learn more about your ad-choices at https://www.iheartpodcastnetwork.com

Sarah Gilbert started working on a vaccine for Covid-19 just as soon as the virus genome was sequenced. Within weeks, she had a proof of principle. By early April, her team at the Jenner Institute in Oxford had manufactured hundreds of doses ready for use in clinical trials. In phase one of these trials, completed in July, this vaccine was shown to be safe for use in a thousand healthy volunteers, aged between 18 and 55. It also provoked exactly the kind of immune response to Covid-19 that Sarah was hoping to achieve. Larger scale clinical trials are currently underway in the UK, South Africa and Brazil. If everything goes according to plan and the vaccine meets all the necessary regulatory standards, it will be manufactured in multiple locations including the Serum Institute in India and made available for use in low to middle income countries. AstraZeneca has already committed to making two billion doses, each costing about $4. The UK has an order in for 100 million. Sarah talks to Jim Al-Khalili about her life and work. As a young woman, she nearly gave up on a career in science. Now she's in charge of one the most successful vaccine projects in the world. How did Sarah and her Oxford team get so far, so fast in developing a vaccine against Covid-19? Producer: Anna Buckley

In this episode the guest joins me from Spain. We discuss about vaccines and specifically about the oxford vaccine. The paper titled “Safety and Immunogenicity of the ChAdOx1 CoV-19 vaccine against SARS-CoV-2: a preliminary report of phase ½, single-blinded, randomised control trial” was published on the Lancet journal on the 20th of July 2020. Link to the paper: https://www.thelancet.com/action/showPdf?pii=S0140-6736%2820%2931604-4 I have attached the link of the paper with the description. It is based on the results of the Phase 1/2 clinical trial of the oxford vaccine. It would be wonderful if you can have a look at the paper. We have a special episode for our patreon members where we discuss about the results of the trial in more detail and it will get published on patreon page by tonight. In this episode we discuss about the vaccine itself and on how the oxford vaccine group managed to get forward with the vaccine so fast. We also discuss about the results in brief and explore the safety profile of the vaccine. And neither of us are experts in the field of vaccine making but both of us find this process to be very fascinating and would love to share the fascination with all of you. I would also like to request you to send huge applauses to the Jenner Institute and the Oxford vaccine groups and specially the authors of this Lancet paper for such an incredible work. They are real heroes. Let's find out why!

There's been encouraging news about the Oxford Covid-19 vaccine this week from a trial involving about 1,000 people. But how great is the challenge in scaling up from making a few thousand doses of the vaccine to manufacturing two billion by the end of this year? Sandy Douglas of Oxford's Jenner Institute explains how they plan to mass-produce the vaccine safely given the speed and magnitude of the scale up. A new kind of treatment for Covid-19 may come from an unlikely source: llamas and alpacas, the South American relatives of the camel. Camelids produce unusually small and simple antibodies against viruses, including the coronavirus. This feature may make these molecules an effective Covid-19 therapy. Jane Chambers reports on research in Chile and the UK. Also in the programme: what has made just a few mosquito species evolve a preference for biting humans, and the theory that 800 million years ago the Moon and the Earth were bombarded by a shower of asteroids which plunged the Earth into a global ice age - an event which changed the course of the evolution of life. These days we're more acquainted with soap than ever before, as we lather up to help stop the spread of coronavirus. And for CrowdScience listener Sharon, this set off a steady stream of soapy questions: how does soap actually work? How was it discovered in the first place, long before anyone knew anything about germs? Are different things used for washing around the world, and are some soaps better than others? We set up a CrowdScience home laboratory to explore the soap making process with advice from science-based beauty blogger Dr Michelle Wong, and find out what it is about soap's chemistry that gives it its germ-fighting superpowers. Soap has been around for at least 4000 years; we compare ancient soap making to modern methods, and hear about some of the soap alternatives used around the world, like the soap berries of India. And as for the question of whether some soaps are better than others? We discover why antibacterial soaps aren't necessarily a good idea, and why putting a toy inside a bar of soap might be more important than tweaking its ingredients. (Image: A team of experts at the University of Oxford are working to develop a vaccine that could prevent people from getting Covid-19. Credit: Press Association)

There’s been encouraging news about the Oxford Covid-19 vaccine this week from a trial involving about 1,000 people. But how great is the challenge in scaling up from making a few thousand doses of the vaccine to manufacturing two billion by the end of this year? Sandy Douglas of Oxford’s Jenner Institute explains how they plan to mass-produce the vaccine safely given the speed and magnitude of the scale up. A new kind of treatment for Covid-19 may come from an unlikely source: llamas and alpacas, the South American relatives of the camel. Camelids produce unusually small and simple antibodies against viruses, including the coronavirus. This feature may make these molecules an effective Covid-19 therapy. Jane Chambers reports on research in Chile and the UK. Also in the programme: Roland talks to Noah Rose and Lindy McBride of Princeton University about what has made just a few mosquito species evolve a preference for biting humans, and the theory that 800 million years ago. He also talks to Professor Kentaro Terada of Osaka University and David Kring of the Lunar and Planetary Institute in the USA about evidence that the Moon and the Earth were bombarded by a shower of asteroids which plunged the Earth into a global ice age – an event which may have changed the course of the evolution of life. (Image: A team of experts at the University of Oxford are working to develop a vaccine that could prevent people from getting Covid-19 Credit: Press Association) Presenter: Roland Pease Producer: Andrew Luck-Baker

The University of Witwatersrand (WITS) has launched the country’s first vaccination trials. The vaccination, which is technically named ChAdOx1-nCOV-19, is aimed at preventing infection by the virus that causes COVID-19.   The trial is a partnership between WITS and the University of Oxford’s Jenner Institute, in the UK. It’s supported by the national Department of Health and the South Africa Medical Research Council (SAMRC), while the R150 million bill is funded by the Bill and Melinda Gates Foundation.  More than 100 vaccines are currently under development around the world with at least five of them undergoing human trials at the moment. Topic: Vaccine development process Guest: Dr John Woodland, Postdoctoral medicinal chemist with the Drug Discovery and Development Centre  at University of Cape Town Host: Africa Melane, Early Breakfast See omnystudio.com/policies/listener for privacy information.

Covid-19, da Oxford arriva una sperimentazione promettente. Ma i vaccini a cui si sta lavorando sono decine e decine in tutto il mondo

Dr Teresa Lambe from the Jenner Institute at Oxford University, one of the researchers behind the British Covid-19 vaccine trials, joins us on this week's episode. She talks to presenter Sinéad O'Carroll about how the UK trial in particular is going, and gives us an insight into this week's good news that this vaccine was found to be safe and induce an immune reaction in the early stages of the trial. Features a clip from Lancet Voice.

Good news on the vaccine front. Professors Sarah Gilbert, Andrew Pollard, the Jenner Institute and the Oxford Vaccine Group have found their vaccine causes immunity, which is a good first step. The government are of course crowing about it as if Sausage Johnson himself had excreted the cure from his armpit. *Swearing*

shutterstock South African researchers, in collaboration with Oxford University’s Jenner Institute, are trialling a vaccine for the COVID-19. Trials of this nature are important because they give robust data about the safety of vaccines. Being part of the trial will also mean that South Africa won’t lag behind should a vaccine prove to work. But how exactly does the trial work? Who receives the vaccine and the placebo? Are South African volunteers being used as “guinea pigs”? In this episode of Pasha, Shabir Madhi, professor of vaccinology and Director of the MRC Respiratory and Meningeal Pathogens Research Unit at the University of the Witwatersrand, answers these questions and explains the benefits of the trial. Photo: “Vaccine and syringe injection” By joel bubble ben Shutterstock Music “Happy African Village” by John Bartmann, found on FreeMusicArchive.org licensed under CC0 1. “Free Music Background Loop 001” by Slaking_97 found on Freesound licensed under Attribution License.

BizNews — There are nearly 150 vaccines under development in the world for Covid-19. The frontrunner at the moment is the vaccine that is being developed by the Jenner Institute at Oxford University, which is being trialled in humans in the United Kingdom. AstraZeneca, which is producing the vaccine for the university, is so confident it will work that it has started beefing up production to have available 100 million doses in October. One of the concerns about the development of vaccines is that countries like South Africa will be at the back of the queue. South Africa has, however, now been given the opportunity to trial the Oxford Covid-19 vaccine. The University of the Witwatersrand started human trials this week. The Dean of the Faculty of Health Sciences at the University of the Witwatersrand, Prof Martin Veller told Biznews about the importance of trials in African populations and gave a sobering assessment of the timeline for vaccines and how our health services will cope with the rapid increase in coronavirus cases that the country is experiencing. – Linda van Tilburg

BizNews — There are nearly 150 vaccines under development in the world for Covid-19. The frontrunner at the moment is the vaccine that is being developed by the Jenner Institute at Oxford University, which is being trialled in humans in the United Kingdom. AstraZeneca, which is producing the vaccine for the university, is so confident it will work that it has started beefing up production to have available 100 million doses in October. One of the concerns about the development of vaccines is that countries like South Africa will be at the back of the queue. South Africa has, however, now been given the opportunity to trial the Oxford Covid-19 vaccine. The University of the Witwatersrand started human trials this week. The Dean of the Faculty of Health Sciences at the University of the Witwatersrand, Prof Martin Veller told Biznews about the importance of trials in African populations and gave a sobering assessment of the timeline for vaccines and how our health services will cope with the rapid increase in coronavirus cases that the country is experiencing. – Linda van Tilburg

A 150-million rand large-scale clinical trial for a COVID19 vaccine begins in South Africa on today. This has been announced at a virtual media conference hosted by the University of the Witwatersrand. The trial titled "South African Ox1Cov-19 Vaccine VIDA-Trial" is sponsored by the University of Oxford and the Jenner Institute and funded by the South African Medical Research Council and the Bill and Melinda Gates Foundation. The vaccine is made from a weakened version of a common cold virus.

Vaccine 411 061120This is Vaccine 4-1-1, As the race for a COVID-19 vaccine continues, here are the numbers:136 vaccines are in development, according to the World Health Organization. 126 are in pre-clinical trials. 7 are in Phase 1 Clinical Trials2 are in Phase 2 one each from the U.S. and China1 is in Phase 2b/3 in the United KingdomOn this episode of Vaccine 411… a dive in to The University of Oxford and AstraZeneca's leading candidate. First, the news… Good news from Johnson and Johnson, they are ahead of schedule and will begin Phase I early stage human trials in late July as opposed to September. NBC news reports, Johnson and Johnson are using the same technology they employed in their experimental Ebola vaccine in late 2019. If the vaccine is a success, they intend to have 600 to 900 million doses available by April 2021. Reuters reports The Beijing Institute of Biological Products, published a paper in “Cell” medical journal, noting that their vaccine has triggered high level, neutralizing antibodies that can block the virus from infecting cells. And that it raised no safety issues in monkeys. A phase I human trial is under way. Coronavirus Task Force Member Dr. Fauci, told CNN the U.S. Government will help fund three Phase III vaccine studies: Moderna, Johnson and Johnson and Oxford University/AstraZeneca. The Jenner Institute at Oxford University had a bit of a head start in the race for the COVID-19 vaccine. The lab had previously developed the technology needed for the vaccine while working on other viruses, including a close cousin of COVID-19. They were able to adapt and modify a weakened version of the common cold virus with spike glycoprotein from the COVID-19 virus. Tricking the body in to fighting the fake COVID-19 virus and creating antibodies for future protection from the real virus. Phase I trials began in April with over 1,000 participants, Phase II saw an increase in age range, Phase III will add 10,000 participants in the UK, 30,000 in the U.S. and 2,000 in Brazil to monitor how well the vaccine works on the larger sample. Participants will randomly receive one or two doses of the potential vaccine or a licensed vaccine as a “control” for comparison. Results are expected in August, which means there could be a vaccine ready by September. The University partnered with British pharmaceutical company AstraZeneca in April to develop, manufacture and distribute the vaccine if successful. The British and U.S. government are also funding development. If successful, the UK will receive 100 million doses, followed by the U.S. with 300 million. Side note, according to MarketWatch, AstraZeneca has a 7.7% stake in Moderna, the Massachusetts based company that also has a promising vaccine candidate. For the latest updates, subscribe for free to Vaccine 411 on your podcast app or ask your smart speaker to play the Vaccine 411 podcast. See acast.com/privacy for privacy and opt-out information.

Finding a vaccine is, of course, something that everyone would like to see, but it is also a key topic for financial markets. Barclays' Gerald Moser speaks with Adrian Hill, director of the Jenner Institute, on the complixities of developing a vaccine.

BizNews — In the race for a new vaccine against Covid-19, Oxford University’s Jenner Institute has emerged as the front runner among 90 institutions who are developing a vaccine against the virus. The Director of Oxford’s Jenner Institute, prof Adrian Hill told Biznews that the institute was able to move very rapidly into clinical trials because of their experience in developing an Ebola vaccine. Prof Hill also said at the end of March that he was confident that they could do it much faster than the 12 to 18 months that most scientists predicted. This week the institute indicated that they were hoping to get some signal by the middle of June on whether it was working on humans and that they have partnered with pharmaceutical giant AstraZeneca for the manufacturing and distribution of the Oxford Covid-19 vaccine, if their vaccine worked. But AstraZeneca has decided to push ahead with the manufacture of the inoculation and will be producing millions of doses of the trial coronavirus vaccine even before the research is complete in a major show of confidence in the Oxford product. In this news clip published with permission from NBC; the Chief Executive Officer of AstraZeneca, Pascal Soriot tells Richard Engel that the vaccine will be made available during the pandemic at cost price. – Linda van Tilburg

BizNews — In the race for a new vaccine against Covid-19, Oxford University’s Jenner Institute has emerged as the front runner among 90 institutions who are developing a vaccine against the virus. The Director of Oxford’s Jenner Institute, prof Adrian Hill told Biznews that the institute was able to move very rapidly into clinical trials because of their experience in developing an Ebola vaccine. Prof Hill also said at the end of March that he was confident that they could do it much faster than the 12 to 18 months that most scientists predicted. This week the institute indicated that they were hoping to get some signal by the middle of June on whether it was working on humans and that they have partnered with pharmaceutical giant AstraZeneca for the manufacturing and distribution of the Oxford Covid-19 vaccine, if their vaccine worked. But AstraZeneca has decided to push ahead with the manufacture of the inoculation and will be producing millions of doses of the trial coronavirus vaccine even before the research is complete in a major show of confidence in the Oxford product. In this news clip published with permission from NBC; the Chief Executive Officer of AstraZeneca, Pascal Soriot tells Richard Engel that the vaccine will be made available during the pandemic at cost price. – Linda van Tilburg

An Oxford team of scientists led by Professor Adrian Hill, who heads the Jenner Institute, is surging ahead in the global race to find a vaccine to cure COVID-19. Pune-based organisation Serum Institute of India has even partnered with them to begin manufacturing of the vaccine, in anticipation that it will be cleared for safety and efficacy by as early as September. On episode 456 of ThePrint’s #CutTheClutter, Shekhar Gupta explains how this team is managing work at such speed when vaccines usually take years to develop.

#金正恩生死之謎 4/15是北韓紀念金日成的重要節日，這個太陽節的活動金正恩並未出席，也因此網路上開始有金正恩動手術失敗導致植物人的消息流傳，甚至傳言他已離開人世，而還有另一派說法則是他沒有動手術，只是為了防疫而隔離，總之，金正恩沒有出席太陽節，而北韓又是個特別神秘的國家，外界對他的生死之謎相當關注… #美伊關係 4/22伊朗發射軍事衛星，在此之前伊朗革命衛隊的海軍也接近美國在波斯灣的海軍，因此4/22美國總統川普發推特命令海軍可以擊沈騷擾的伊朗船艦，而問題在於，總統的推特算不算正式軍事命令？美伊劍拔弩張的情勢又源自於哪些因素？ #疫情動態 英國牛津大學詹納實驗室（the Jenner Institute）在紐約時報報導，自己在疫苗的研究上領先全球，下個月底將完成六千人的實驗，若一切進展順利，疫苗將在九月問世。在疫苗研發上，各國都在賽跑，看誰能先研發出疫苗…此外，上週美國國務院公佈，原本預算給WHO的經費將轉至其他國際組織或計畫，但卻沒有明確表示哪些組織… 劉必榮教授和風談判學院：negotiation.eletang.com.tw

A vaccine for Covid-19 is seen as the way out to end the lockdowns that are crippling economies around the world - because easing lockdowns without a vaccine in place could see health services overwhelmed with coronavirus cases. But the big question is: when will a vaccine be ready? A global race is happening right now to fast-track efforts to develop one. Among the teams involved is one from the Jenner Institute at the University of Oxford - they plan to start human trials of a vaccine in the coming days.ITV News Science Editor Tom Clarke and ITV News Health Correspondent Emily Morgan spoke to Professor Adrian Hill, Director of the Jenner Institute at the University of Oxford. He told us about the trial he's involved in, and why he thinks it will be the first one to finish testing this summer, and - if all goes well - how GPs could be giving the vaccines to patients by the end of the year. He also explained why waiting for coronavirus cases to drop would actually harm efforts to quickly develop a vaccine. The Oxford trial is receiving funding as part of a government vaccine taskforce announced on Friday.We regularly release new episodes of Coronavirus: What You Need To Know - subscribe to be notified of the latest episodes. For the latest coronavirus news, information and advice, go to www.itv.com/news.

Covid- 19 cases seem to be multiplying daily and there is now a growing body of scientific evidence both on its spread and the effectiveness of measures to try and control it. We look at what’s working, what’s not and why. And we look to the potential for coronavirus drug treatments, why despite the hype there really isn’t anything round the corner. Australia’s recent fire season was intense; a new study looks back over 500 years of the weather pattern partly responsible, the Indian Ocean Dipole. The findings show the most extreme years occurred recently – under the influence of man-made climate change. And we look at life deep below the sea floor, microbes which multiply slowly over centuries and eat their neighbours. Since the outbreak of a new strain of coronavirus late last year, health workers and governments have been rushing to limit transmission by deploying containment tactics and anti-contamination campaigns. But, as the virus spreads around the world, what are scientists doing to help our bodies fight off or resist this new infectious disease? Viruses that cause human disease can be notoriously tricky to tackle. They don’t respond to antibiotics, can spread rapidly between human hosts, and even evolve improved ways of working as they multiply. Presenter Marnie Chesterton heads to the University of Oxford’s Nuffield Department of Medicine to meet the researchers who are urgently searching for solutions. Professor Tao Dong is Director of Chinese Academy of Medical Sciences Oxford Institute, collaborating with colleagues on the ground in China to see how Chinese patients’ immune systems are responding to the virus, which could inform vaccine design. Professor Sarah Gilbert leads the Jenner Institute’s influenza vaccine and emerging pathogens programme. She’s been developing a vaccine against another strain of coronavirus that caused the Middle East Respiratory Syndrome (MERS) outbreak, and is using the same technology to generate a new vaccine against the 2019 coronavirus. And, whilst that’s being developed, there is a possibility that some existing antiviral drugs may even help infected patients – Professor Peter Horby is working with colleagues in China on clinical trials to see what might work. CrowdScience goes into the laboratories using cutting edge science to combat coronavirus. (Image: Coronavirus test. Credit: iStock / Getty Images Plus)

Since the outbreak of a new strain of coronavirus late last year, health workers and governments have been rushing to limit transmission by deploying containment tactics and anti-contamination campaigns. But, as the virus spreads around the world, what are scientists doing to help our bodies fight off or resist this new infectious disease? Viruses that cause human disease can be notoriously tricky to tackle. They don’t respond to antibiotics, can spread rapidly between human hosts, and even evolve improved ways of working as they multiply. Presenter Marnie Chesterton heads to the University of Oxford’s Nuffield Department of Medicine to meet the researchers who are urgently searching for solutions. Professor Tao Dong is Director of Chinese Academy of Medical Sciences Oxford Institute, collaborating with colleagues on the ground in China to see how Chinese patients’ immune systems are responding to the virus, which could inform vaccine design. Professor Sarah Gilbert leads the Jenner Institute’s influenza vaccine and emerging pathogens programme. She’s been developing a vaccine against another strain of coronavirus that caused the Middle East Respiratory Syndrome (MERS) outbreak, and is using the same technology to generate a new vaccine against the 2019 coronavirus. And, whilst that’s being developed, there is a possibility that some existing antiviral drugs may even help infected patients – Professor Peter Horby is working with colleagues in China on clinical trials to see what might work. CrowdScience goes into the laboratories using cutting edge science to combat coronavirus. Presented by Marnie Chesterton Produced by Jen Whyntie for the BBC World Service (Photo: Coronavirus Credit: Getty Images)

Anna Fowler, from the Lunter group at the WTCHG, speaks about how the patterns around a close-call in the desert makes her think about her work. This is the second part of our evening of storytelling and music, where researchers from the Wellcome Trust Centre for Human Genetics, the Jenner Institute, and Cancer Research UK, came together to tell stories about their lives as scientists, with live musical accompaniment from Oxford-based folk group “James Bell and the Half Moon All Stars”. It took place under the dinosaurs at the Oxford University Museum of Natural History.

Irina Pulyakhina, from the Julian Knight group at the WTCHG, speaks about her time helping a Masters student through an important presentation. This is the first part of our evening of storytelling and music, where researchers from the Wellcome Trust Centre for Human Genetics, the Jenner Institute, and Cancer Research UK, came together to tell stories about their lives as scientists, with live musical accompaniment from Oxford-based folk group “James Bell and the Half Moon All Stars”. It took place under the dinosaurs at the Oxford University Museum of Natural History.

An evening of storytelling and music where researchers from the Wellcome Trust Centre for Human Genetics, the Jenner Institute, and Cancer Research UK came together to tell stories about their lives as scientists, with live musical accompaniment. On the 10th of October 2015, The Wellcome Trust Centre for Human Genetics, with support from Cancer Research UK and The Wellcome Trust, put on an evening of storytelling and music where researchers from the Centre, the Jenner Institute, and Cancer Research UK came together to tell stories about their lives as scientists, with live musical accompaniment from Oxford-based folk band “James Bell and the Half Moon All Stars”. It took place under the dinosaurs at the Oxford University Museum of Natural History, and our speakers were Irina Pulyakhina (WTCHG), Anna Fowler (WTCHG), Erwan Atcheson (Jenner), Portia Westall (WTCHG), and Daniel Bulte (CRUK). This track contains the entire evening, but you can listen to specific sections of it in the other tracks in this series.

Erwan Atcheson, from the Jenner Institute, speaks about his time studying parasitic worms, and the worries that come with it. This is the third part of our evening of storytelling and music, where researchers from the Wellcome Trust Centre for Human Genetics, the Jenner Institute, and Cancer Research UK, came together to tell stories about their lives as scientists, with live musical accompaniment from Oxford-based folk group “James Bell and the Half Moon All Stars”. It took place under the dinosaurs at the Oxford University Museum of Natural History.

Daniel Bulte, from the Department of Oncology, speaks about what happens when they discover an ‘incidental finding’. This is the final part of our evening of storytelling and music, where researchers from the Wellcome Trust Centre for Human Genetics, the Jenner Institute, and Cancer Research UK, came together to tell stories about their lives as scientists, with live musical accompaniment from Oxford-based folk group “James Bell and the Half Moon All Stars”. It took place under the dinosaurs at the Oxford University Museum of Natural History.

Portia Westall, from the Donnelly group at the WTCHG, speaks about how she thinks about music when working on DNA sequences. This is the fourth part of our evening of storytelling and music, where researchers from the Wellcome Trust Centre for Human Genetics, the Jenner Institute, and Cancer Research UK, came together to tell stories about their lives as scientists, with live musical accompaniment from Oxford-based folk group “James Bell and the Half Moon All Stars”. It took place under the dinosaurs at the Oxford University Museum of Natural History.

Weatherall lecture 2015, delivered by Professor Adrian Hill. Adrian Hill trained at Trinity College Dublin and Oxford and is now Professor of Human Genetics and Director of the Jenner Institute at Oxford University. He has published over 350 research papers, is a Fellow of the UK Academy of Medical Sciences and the Royal College of Physicians, and a NIHR Senior Investigator. He leads research programmes in genetic susceptibility to tropical infectious diseases and in vaccine design and development. The Weatherall lecture series was named in honour of the Regius Professor Emeritus, Sir David Weatherall, physician and medical researcher whose work focused on molecular genetics, haematology, pathology and clinical medicine. This talk is part of the Medical Sciences Division Events series.

Meet our Insectary at the Jenner Institute. The Jenner Institute Insectary at the Old Road Campus Research Building is used to test vaccines against malaria, targeting the liver and blood stages of malaria infection. The facility is also used to test transmission-blocking malaria vaccines that aim to halt the sexual development of the malaria parasite in the mosquito.

Dr Sumi Biswas talks about the development of a vaccine aimed at the mosquito stage of the malaria parasite cycle. Malaria transmission-blocking vaccines aim to induce immunity against the parasites that infect mosquitoes. Such vaccines will prevent malaria transmission on a wider scale, focusing on the community rather than the individual. Dr Sumi Biswas is working on the development of transmission-blocking vaccines to prevent the spread of malaria.

Dr Sumi Biswas talks about the development of a vaccine aimed at the mosquito stage of the malaria parasite cycle. Malaria transmission-blocking vaccines aim to induce immunity against the parasites that infect mosquitoes. Such vaccines will prevent malaria transmission on a wider scale, focusing on the community rather than the individual. Dr Sumi Biswas is working on the development of transmission-blocking vaccines to prevent the spread of malaria.

Dr Sumi Biswas talks about the development of a vaccine aimed at the mosquito stage of the malaria parasite cycle. Malaria transmission-blocking vaccines aim to induce immunity against the parasites that infect mosquitoes. Such vaccines will prevent malaria transmission on a wider scale, focusing on the community rather than the individual. Dr Sumi Biswas is working on the development of transmission-blocking vaccines to prevent the spread of malaria.

Dr Sumi Biswas talks about the development of a vaccine aimed at the mosquito stage of the malaria parasite cycle. Malaria transmission-blocking vaccines aim to induce immunity against the parasites that infect mosquitoes. Such vaccines will prevent malaria transmission on a wider scale, focusing on the community rather than the individual. Dr Sumi Biswas is working on the development of transmission-blocking vaccines to prevent the spread of malaria.

Professor Sarah Gilbert talks about her work on viral vectored vaccines. Viral vectored vaccines combine a safe virus with a disease protein to protect against specific diseases. These vaccines have the potential to drastically improve public health. Professor Sarah Gilbert has been making and testing vaccines designed to induce T cell responses for ten years, chiefly using antigens from malaria and influenza. Based at the Jenner Institute, several of the vaccines developed in Professor Gilbert's laboratory have progressed into clinical trials.

Professor Sarah Gilbert talks about her work on viral vectored vaccines. Professor Sarah Gilbert has been making and testing vaccines designed to induce T cell responses for ten years, chiefly using antigens from malaria and influenza. Based at the Jenner Institute, several of the vaccines developed in Professor Gilberts laboratory have progressed into Clinical Trials.

Professor Sarah Gilbert talks about her work on viral vectored vaccines. Professor Sarah Gilbert has been making and testing vaccines designed to induce T cell responses for ten years, chiefly using antigens from malaria and influenza. Based at the Jenner Institute, several of the vaccines developed in Professor Gilberts laboratory have progressed into Clinical Trials.

Dr George Warimwe talks about his research on Rift Valley Fever. Dr George Warimwe is working with the International Livestock Research Institute (ILRI) A Centre of Excellence in Africa, and the Jenner Institute to develop a vaccine against Rift Valley Fever in humans, that will also be useful as a vaccination against the disease in livestock.

Dr George Warimwe talks about his research on Rift Valley Fever. Dr George Warimwe is working with the International Livestock Research Institute (ILRI) A Centre of Excellence in Africa, and the Jenner Institute to develop a vaccine against Rift Valley Fever in humans, that will also be useful as a vaccination against the disease in livestock.

Dr George Warimwe talks about his research on Rift Valley Fever. Rift Valley Fever is a mosquito-borne virus, which affects both livestock and humans in Africa and parts of the Middle East. There is currently no licensed vaccine for use in humans. Amid fears that the virus may spread to Europe, Dr George Warimwe is working with the International Livestock Research Institute (ILRI) in Africa, and the Jenner Institute to develop a vaccine against Rift Valley Fever for both humans and livestock.

Dr George Warimwe talks about his research on Rift Valley Fever. Rift Valley Fever is a mosquito-borne virus, which affects both livestock and humans in Africa and parts of the Middle East. There is currently no licensed vaccine for use in humans. Amid fears that the virus may spread to Europe, Dr George Warimwe is working with the International Livestock Research Institute (ILRI) in Africa, and the Jenner Institute to develop a vaccine against Rift Valley Fever for both humans and livestock.

Meet the Jenner Institute. The Jenner Institute focuses both on diseases of humans and livestock. One of the founding principles of the Institute is the exploitation of synergies in the development of human and veterinary vaccines whereby new vaccine approaches can be tested in parallel in different species.

What are the best ways to control the global problem of tuberculosis? Professor Helen McShane from the Jenner Institute tells us about the MVA85A tuberculosis vaccine from her lab that’s currently undergoing large-scale clinical trials and the impact it could have on the incidence of TB around the world. This episode of Microbe Talk has been produced for World TB Day on Saturday 24 March.

Professor Adrian Hill talks about recent developments of vaccines against malaria. Around half of the world's population is at risk of contracting malaria. After studying malaria susceptibility in African children for many years, Professor Adrian Hill is now developing a vaccine against malaria by inducing cellular immune responses (T lymphocytes), instead of taking the more common research approach of stimulating antibodies. Prophylactic vaccines developed in Oxford are now showing great promise in clinical trials.

Professor Adrian Hill talks about recent developments of vaccines against malaria. Around half of the world's population is at risk of contracting malaria. After studying malaria susceptibility in African children for many years, Professor Adrian Hill is now developing a vaccine against malaria by inducing cellular immune responses (T lymphocytes), instead of taking the more common research approach of stimulating antibodies. Prophylactic vaccines developed in Oxford are now showing great promise in clinical trials.